CN116008532A - Fecal immediate detection device for realizing transfer of reaction reagent through position switching - Google Patents
Fecal immediate detection device for realizing transfer of reaction reagent through position switching Download PDFInfo
- Publication number
- CN116008532A CN116008532A CN202211666941.XA CN202211666941A CN116008532A CN 116008532 A CN116008532 A CN 116008532A CN 202211666941 A CN202211666941 A CN 202211666941A CN 116008532 A CN116008532 A CN 116008532A
- Authority
- CN
- China
- Prior art keywords
- fecal
- groove
- sealing
- reagent tube
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 87
- 230000002550 fecal effect Effects 0.000 title claims abstract description 70
- 238000001514 detection method Methods 0.000 title claims abstract description 51
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 19
- 238000012546 transfer Methods 0.000 title claims abstract description 10
- 238000007789 sealing Methods 0.000 claims abstract description 85
- 238000005070 sampling Methods 0.000 claims abstract description 53
- 238000012360 testing method Methods 0.000 claims abstract description 47
- 239000007788 liquid Substances 0.000 claims abstract description 25
- 239000000376 reactant Substances 0.000 claims abstract description 8
- 210000003608 fece Anatomy 0.000 claims description 11
- 238000007790 scraping Methods 0.000 claims description 11
- 239000002274 desiccant Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 230000008569 process Effects 0.000 claims description 6
- 230000009471 action Effects 0.000 claims description 3
- 230000013011 mating Effects 0.000 claims description 2
- 238000004891 communication Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 abstract description 3
- 238000011002 quantification Methods 0.000 abstract description 3
- 238000009423 ventilation Methods 0.000 description 7
- 238000013461 design Methods 0.000 description 4
- 210000002700 urine Anatomy 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 108010025899 gelatin film Proteins 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 239000000741 silica gel Substances 0.000 description 3
- 229910002027 silica gel Inorganic materials 0.000 description 3
- 241000590002 Helicobacter pylori Species 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 229940037467 helicobacter pylori Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
Images
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention provides a fecal immediate detection device for realizing reactant transfer through position switching, which comprises: a device body having a sealed cavity in which a test paper is accommodated; the reagent tube is inserted into the sealing cavity and is a hollow tube body; the sampling rod is in sealing connection with the second opening of the hollow tube body, the sampling rod comprises a rod body, the first end of the rod body is provided with a fecal accommodating structure, the fecal accommodating structure is provided with a first position and a second position, when the fecal accommodating structure is positioned at the first position, the fecal accommodating structure is positioned in a reaction reagent in the reagent tube, and when the fecal accommodating structure is positioned at the second position, the fecal accommodating structure can puncture the sealing structure so that the reaction reagent flows into the sealing cavity through the flow passage. The user of the invention adopts the sampling rod to sample and then inserts the sampling rod into the reagent tube, and realizes the transfer of the reaction reagent and the detection by switching the fecal accommodating structure from the first position to the second position, and the quantification of the sample liquid entering the sealing cavity is realized by the displacement and the movement amount from the first position to the second position.
Description
Technical Field
The invention belongs to the technical field of instant detection, and particularly relates to a fecal instant detection device for realizing transfer of a reaction reagent through position switching.
Background
With the improvement of the living standard of people and the development of biotechnology, the pursuit and the attention of people to health are also more prominent, and the fecal detection which is one of three general detection is an alarm for various digestive tract diseases. Recently, helicobacter pylori is more alert to people, and mainly the risk of gastric cancer of the infected people can be increased by 4-6 times compared with normal people, the infection rate in the people in China exceeds 50%, and as a detection method, the accuracy rate of detecting helicobacter pylori by feces can reach more than 98%, so that the method has wide application prospect in the future.
The existing fecal detection method, such as colloidal gold, has the advantages of convenient operation, rapid detection and capability of meeting the requirement of home self-test, but has the defects of difficult sampling, incapability of quantification and relatively complex device operation.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to provide the fecal immediate detection device for realizing the transfer of the reaction reagent through position switching, so as to overcome the defect that the device is complicated to operate during fecal detection in the prior art.
In order to solve the above problems, the present invention provides an instant fecal testing device, comprising:
the device comprises a device body, a detection device and a control unit, wherein the device body is provided with a sealing cavity, detection test paper is contained in the sealing cavity, and the sealing cavity is provided with a first opening;
the reagent tube is internally provided with a reaction reagent, is inserted into the sealing cavity through the first opening, is a hollow tube body, and has a sealing structure at the first end and a second opening at the second end;
the sampling rod is in sealing connection with the second opening, the sampling rod comprises a rod body, a first end of the rod body is provided with a fecal accommodating structure, a flow passage is formed in the fecal accommodating structure, the fecal accommodating structure is provided with a first position and a second position, when the fecal accommodating structure is positioned at the first position, the fecal accommodating structure is positioned in the reaction reagent in the reagent tube, when the fecal accommodating structure is positioned at the second position, the fecal accommodating structure can puncture the sealing structure so that the reaction reagent in the reagent tube flows into the sealing cavity through the flow passage, the sealing structure is in sealing contact with the rod body, the inlet of the flow passage is positioned in the reagent tube, and the outlet of the flow passage is positioned in the sealing cavity.
In some embodiments, the rod body has a sealing connection section, and the sealing connection section is in sealing connection with the second opening in a state that the fecal accommodation structure is inserted into the reagent tube.
In some embodiments, a scraping plate extending from outside to inside along the radial direction of the hollow tube body is further configured in the hollow tube body, and the scraping plate can scrape off excessive feces accommodated by the feces accommodating structure in the process of inserting the feces accommodating structure into the reagent tube; and/or one side of the sealing connection section far away from the excrement containing structure is provided with a handheld part.
In some embodiments, the reagent tube is snap-fit with the first opening; and/or the sealing structure is a sealing flexible film.
In some embodiments, the area of the sealing cavity corresponding to the reagent tube is a second area, the remaining area of the sealing cavity is a first area, the test paper is located in the first area, the bottom wall of the sealing cavity is provided with a drainage surface based on the orientation of the device in the use state, and the sample liquid flowing out of the reagent tube flows from the second area to the first area under the action of the drainage surface.
In some embodiments, the fecal immediate detection device further comprises a test paper fixing plate inserted in the first area, and the detection test paper is fixed on the test paper fixing plate.
In some embodiments, the test strip fixing plate has an assembly groove in which a desiccant is assembled.
In some embodiments, the second opening of the reagent tube is provided with an assembly matching structure, the assembly matching structure comprises a guide groove configured on the inner wall of the second opening, the guide groove comprises a first vertical groove, a second vertical groove and a first horizontal groove, the first vertical groove and the first horizontal groove are communicated with the bottom end of the first vertical groove and the top end of the second vertical groove, the extending direction of the groove body of the first vertical groove is consistent with the inserting direction of the sampling rod and penetrates through the assembly matching structure, the assembly matching structure is far away from one side end surface of the sealing cavity, the sampling rod is provided with a guide protrusion, and the guide protrusion is matched with the guide groove.
In some embodiments, the assembly mating structure further comprises a positioning groove configured on an inner wall of the second opening, and the sampling rod is provided with a positioning protrusion, and the positioning protrusion is matched with the positioning groove.
In some embodiments, the guide groove further includes a second transverse groove parallel to the first transverse groove and one end of which communicates with the second vertical groove, the second transverse groove being adapted to the positioning protrusion.
According to the fecal immediate detection device for realizing the transfer of the reaction reagent through position switching, when the fecal immediate detection device is used for detection, a user adopts the sampling rod to sample and inserts the sampling rod into the reagent tube, the transfer of the reaction reagent is realized and the detection is completed through the switching from the first position to the second position of the fecal accommodating structure, the professional operations such as the assembly of a plurality of parts and the pipetting are not involved in the operation, the operation is simple and convenient, the assembled parts are fewer, the production cost can be reduced, the inlet and the outlet of the flow passage are respectively positioned in the reagent tube and the sealing cavity in the second position, and the quantification of sample liquid entering the sealing cavity is realized by the displacement and movement amount from the first position to the second position, so that the detection result of the subsequent detection test paper can be more accurate.
Drawings
Fig. 1 is a schematic view of an embodiment of an apparatus for detecting feces in real time;
FIG. 2 is a schematic diagram showing the internal structure of the fecal immediate detection device of FIG. 1;
fig. 3 is a schematic view of the internal structure of the device body in fig. 2;
FIG. 4 is a schematic view showing the external structure of the reagent vessel in FIG. 2;
FIG. 5 is a top view of FIG. 4;
FIG. 6 is a schematic view (in section) showing the internal structure of the reagent vessel in FIG. 2;
FIG. 7 is a schematic view of the appearance of the sampling rod in FIG. 2;
FIG. 8 is a schematic diagram of the structure of the test strip fixing plate in FIG. 2;
FIG. 9 is a top view of FIG. 8;
fig. 10 is a schematic diagram of a structure of assembling a test strip and a desiccant on the test strip fixing plate in fig. 2.
The reference numerals are expressed as:
1. a device body; 11. sealing the cavity; 12. a drainage surface; 13. a clamping groove; 2. detecting test paper; 3. a reagent tube; 31. scraping a sample plate; 321. a first vertical groove; 322. a second vertical groove; 323. a first transverse slot; 324. a second transverse slot; 33. a positioning groove; 34. a second airtight ring groove; 341. a second seal ring; 35. a third seal ring; 351. a third airtight ring groove; 36. a sealing structure; 37. a buckle; 4. a sampling rod; 41. a rod body; 411. a first airtight ring groove; 412. a first seal ring; 42. a fecal accommodating structure; 421. a flow-through channel; 46. a hand-held part; 47. a guide protrusion; 48. positioning the bulge; 51. test paper fixing plate; 511. an assembly groove; 512. a test paper clamping groove; 52. a drying agent; 100. a first region; 101. a second region; 102. a first ventilation channel; 103. and a second ventilation channel.
Detailed Description
Referring now to fig. 1 to 10 in combination, according to an embodiment of the present invention, there is provided a fecal immediate detection device including: the device comprises a device main body 1, wherein the device main body 1 is provided with a sealing cavity 11, the detection test paper 2 is contained in the sealing cavity 11, and the sealing cavity 11 is provided with a first opening; the reagent tube 3 is provided with a reaction reagent, the reagent tube 3 is inserted into the sealing cavity 11 through the first opening, the reagent tube 3 is a hollow tube body, the first end of the hollow tube body is provided with a sealing structure 36, and the second end of the hollow tube body is provided with a second opening; the sampling rod 4 is in sealing connection with the second opening, the sampling rod 4 comprises a rod body 41, a first end of the rod body 41 is provided with a fecal accommodating structure 42, a through-flow channel 421 is arranged at the fecal accommodating structure 42, the fecal accommodating structure 42 is provided with a first position and a second position, when the fecal accommodating structure 42 is in the first position, the fecal accommodating structure 42 is positioned in the reactant in the reagent tube 3, when the fecal accommodating structure 42 is in the second position, the fecal accommodating structure 42 can puncture the sealing structure 36 to enable the reactant in the reagent tube 3 to flow into the sealing cavity 11 through the through-flow channel 421, the sealing structure 36 is in sealing contact with the rod body 41 to prevent sample liquid from entering the sealing cavity 11 from the puncture position, the inlet of the through-flow channel 421 is positioned in the reagent tube 3, the export of the overflow channel 421 is in sealed chamber 11, sampling rod 4 is in the unset state, its cartridge in the second opening part forms sealedly to the second opening, prevent the leakage of the reactant in the reagent pipe 3, and when sampling rod 4 is used for taking a sample, the user pulls out sampling rod 4 from the second opening part and takes a sample, insert sampling rod 4 again at second opening part after the sample makes excrement and urine containment structure 42 be in the first position, excrement and urine containment structure 42 submerges in the reaction fully and reacts, the user switches excrement and urine containment structure 42 into the second position after the reaction finishes, reactant gets into sealed chamber 11 and with the test paper 2 contact chromatography in it through overflow channel 421 realizes the detection purpose. In this technical scheme, when detecting, the user adopts sample rod 4 sample back cartridge to put into in reagent pipe 3 and through the switching of excrement and urine holding structure 42 from first position to second position to realize reagent's transfer and accomplish the detection, do not involve the equipment of a plurality of parts and professional operations such as pipetting during the operation, easy operation, convenient, and the part of equipment is less, can reduce manufacturing cost, more importantly, under the second position, the import and the export of overflow channel 421 are in reagent pipe 3 and sealed chamber 11 respectively, and rely on the displacement amount of first position to the second position to realize the ration of sample liquid (i.e. reagent and sample's mixed solution) that gets into sealed chamber 11, and then can make the testing result of follow-up test paper 2 more accurate.
The foregoing through-flow channel 421 can specifically drill a blind hole along the axial direction of the rod 41, and then drill a corresponding inlet and outlet from the side surface of the rod 41, and after that, it is preferable to fill and seal the axial process port of the through-flow channel 421, so as to prevent the problem of large deviation of the quantitative sampling caused by the sample entering the through-flow channel 421 during sampling.
In a specific embodiment, the rod 41 has a sealing connection section, and in a state that the fecal storage structure 42 is inserted into the reagent tube 3, the sealing connection section is in sealing connection with the second opening, as shown in fig. 7, a plurality of circles of first airtight ring grooves 411 are configured on the outer peripheral wall of the rod 41 corresponding to the sealing connection section, and a first sealing ring 412 is respectively sleeved on the outer peripheral wall of the rod 41, and is in elastic sealing contact with the inner wall of the second opening, so that the gas in the reagent tube 3 can be compressed more reliably and stably in the process that the sampling rod 4 is switched from the first position to the second position, and the reaction reagent in the reagent tube 3 can flow out into the sealing cavity 11 accurately and quantitatively. It should be noted that, in this case, the sealing connection section will force the sample liquid in the reagent tube 3 to enter the sealing chamber 11 through the flow channel 421 in an injection manner during the position switching, and in the state where the sampling rod 4 is switched to the second position, since the sampling rod 4 is no longer pushed down, the sample liquid in the reagent tube 3 lacks the drive of the necessary compressed gas, and the sample liquid no longer enters the sealing chamber 11 through the flow channel 421 even if the liquid level of the sample liquid remaining in the reagent tube 3 is above the inlet of the flow channel 421 in this state.
Referring to fig. 6, a scraping plate 31 extending from outside to inside along the radial direction is further configured in the hollow tube body, and in the process that the fecal accommodating structure 42 is inserted into the reagent tube 3, the scraping plate 31 can scrape the excessive fecal accommodated by the fecal accommodating structure 42, so that quantitative sampling of a fecal sample can be realized, the fecal sampling amount is matched with the reagent preassembling amount (2 mL in a specific embodiment), and the accuracy of the detection result is ensured. In a specific embodiment, the maximum outer diameter of the fecal accommodating structure 42 is not greater than the outer diameter of the rod body 41, the scraping plate 31 is a circular ring structure, and the central through hole aperture of the circular ring structure is equal to the outer diameter of the rod body 41, so that when the fecal accommodating structure 42 passes through the central through hole, the central through hole of the circular ring structure scrapes the portion attached to the outside Zhou Duoyu of the fecal accommodating structure 42 and remains outside the scraping plate 31 (i.e. the side far away from the fecal accommodating structure 42), and the structural design is simple and convenient.
The specific design of the feces receiving structure 42 may be varied, for example, the feces receiving structure 42 is a rectangular groove arranged along the circumferential array of the rod 41; alternatively, the feces accommodating structure 42 is a screw groove provided along the circumferential direction of the rod body 41; or, the excrement containing structure 42 is a spoon body with sharp corners extending along the axial direction of the rod body 41, so that the excrement is conveniently inserted into the spoon body for sampling by using the sharp corner structure, and the volume of each excrement containing structure 42 is designed reasonably according to the required volume of a sample.
In order to prevent the sample liquid (the mixture of the reaction reagent and the sample) from leaking out of the gap between the reagent tube 3 and the chamber wall of the apparatus main body 1, in one preferred embodiment, the outer circumferential wall of the reagent tube 3 is formed with a second airtight ring groove 34, on which a second seal ring 341 is fitted.
In a specific embodiment, the reagent vessel 3 is snap-connected to the first opening, as shown in fig. 3 and 4, and the corresponding clamping groove 13 is configured on the first opening, and the corresponding clamping groove 37 is provided on the corresponding outer wall of the reagent vessel 3, so that the reagent vessel 3 and the device body 1 can be reliably and conveniently connected by the snap fit between the clamping groove 13 and the clamping groove 37.
The sealing structure 36 is a sealing flexible film, for example, may be a silica gel film adhered to the first end of the hollow tube body, so that when the sampling rod 4 is switched from the first position to the second position, that is, after the tip of the tail end of the fecal accommodating structure 42 pierces the silica gel film, the silica gel film will be tightly adhered to the outer circumference side of the rod body 41 by using its own elastic force to form a seal, so that the sample liquid in the reagent tube 3 is prevented from entering the sealing cavity 11 through the pierced gap, and the quantitative entry of the sample liquid through the flow channel 421 is ensured.
It can be understood that the seal chamber 11 has ventilation holes, in which ventilation and hydrophobic films are provided to prevent the liquid from flowing out of the seal chamber 11 while allowing the liquid in the seal chamber 11 to smoothly flow, and the ventilation holes may be formed by, for example, the first ventilation channel 102 formed in the device body 1 and the second ventilation channel 103 formed at the top position of the reagent tube 3.
In order to conveniently check the detection result of the detection test paper 2 in the device main body 1, the device main body 1 should have an observation structure, such as an observation window, and in a preferred embodiment, the device main body 1 is made of transparent materials such as PP plastic, so that the structural design of the device main body 1 is simplified.
Referring to fig. 2 and 3, the area of the sealing cavity 11 corresponding to the reagent tube 3 is the second area 101, the remaining area of the sealing cavity 11 is the first area 100, the test paper 2 is located in the first area 100, the bottom wall of the sealing cavity 11 is provided with a drainage surface 12 based on the direction of the device in use, the sample liquid flowing out of the reagent tube 3 flows from the second area 101 to the first area 100 under the action of the drainage surface 12, the drainage surface 12 is specifically an inclined surface with the height being lower from the second area 101 to the first area 100, and a quantitative and small amount (300 microliters in a specific embodiment) of the sample liquid is guided and collected to the first area 100 for the purpose of contact chromatography with the test paper 2, so that the test result is more accurate.
Referring to fig. 2 and 8, the fecal immediate detection device further includes a test paper fixing plate 51 inserted in the first area 100, and the test paper 2 is fixed on the test paper fixing plate 51, so that the test paper 2 is reliably fixed in the sealed cavity 11, in a specific embodiment, the test paper fixing plate 51 is provided with a test paper clamping groove 512, and in a specific application, the test paper 2 is inserted in the test paper clamping groove 512, fig. 8 shows two test paper clamping grooves 512, so that one test paper 2 can be respectively inserted in the two test paper clamping grooves 512, and the detection items of the two test papers 2 can be different. Referring to fig. 2 and 9 in combination, the test paper fixing plate 51 further has an assembling groove 511, a drying agent 52 is assembled in the assembling groove 511, the assembling position of the drying agent 52 is determined according to the volume of the sample liquid required for detection of the test paper 2, and when the volume of the sample liquid entering the first area 100 exceeds a preset amount, the redundant sample liquid is absorbed by the drying agent 52, so that the accuracy of the detection result is further ensured.
Referring to fig. 4 to 7, the second opening of the reagent tube 3 is provided with an assembling structure (not shown) which comprises a guiding groove formed on the inner wall of the second opening, the guiding groove comprises a first vertical groove 321, a second vertical groove 322 and a first horizontal groove 323 which are arranged in parallel, the bottom end of the first vertical groove 321 is communicated with the top end of the second vertical groove 322, the extending direction of the groove body of the first vertical groove 321 is consistent with the inserting direction of the sampling rod 4 and penetrates through the end face of one side of the assembling structure far away from the sealing cavity 11, the first horizontal groove 323 is perpendicular to the first vertical groove 321 and the second vertical groove 322, the sampling rod 4 is provided with a guiding protrusion 47, the guiding protrusion 47 is matched with the guiding groove, in particular, the sampling rod 4 inserts the excrement containing structure 42 into the second opening after sampling, and further inserting the guide protrusion 47 downward along the axial direction of the reagent vessel 3, wherein the sample rod 4 is in the first position due to the blocking of the bottom end of the first vertical groove 321, the sample in the fecal accommodating structure 42 is fully contacted and reacted with the reactant, then after waiting for a certain reaction time, the user continues to rotate and apply force to the sample rod 4 to horizontally deflect the guide protrusion 47 along the first transverse groove 323 by a certain angle (for example, 45 degrees, the specific angle is determined by the interval between the first vertical groove 321 and the second vertical groove 322), when the guide protrusion 47 enters the second vertical groove 322, the guide protrusion can be further moved downward along the vertical guide direction of the second vertical groove 322 until the bottom end of the second vertical groove 322 is blocked from being further moved downward, thereby reaching the second position, the fecal accommodating structure 42 pushes the sealing structure open, the sample liquid enters the sealing cavity 11 to realize the subsequent detection, according to the technical scheme, the first position and the second position of the sampling rod 4 are switched through axial force application and circumferential force application, and the operation is simple and convenient.
In some embodiments, the assembly and matching structure further comprises a positioning groove 33 configured on the inner wall of the second opening, the sampling rod 4 is provided with a positioning protrusion 48, the positioning protrusion 48 is matched with the positioning groove 33, so that the position of the sampling rod 4 relative to the reagent tube 3 can be relatively stable through the matching buckle of the positioning protrusion 48 and the positioning groove 33, the sampling rod 4 is prevented from being switched from the first position to the second position due to false touch of a user, and it can be understood that the force of combining the positioning protrusion 48 and the positioning groove 33 with each other can meet the requirement that the user can apply axial force to separate from the combination, so that the position of the sampling rod 4 can be switched conveniently, and the adjustment of the combined force can be realized through the design of the protrusion height of the positioning protrusion 48 and the concave depth of the positioning groove 33.
In some embodiments, the guiding groove further comprises a second transverse groove 324, the second transverse groove 324 is parallel to the first transverse groove 323, one end of the second transverse groove 324 is communicated with the second vertical groove 322, the second transverse groove 324 is matched with the positioning protrusion 48, specifically, when the sampling rod 4 is switched to the second position, the positioning protrusion 48 is located in the second transverse groove 324, so that the sampling rod 4 cannot move along the axial direction of the reagent tube 3 in the position, and the positions of the two parts are more stable and reliable.
The bottom end face of the assembly and matching structure is also provided with a third airtight ring groove 351, and a third sealing ring 35 is sleeved in the third airtight ring groove to seal the matching position of the reagent tube 3 and the top of the device main body 1.
The following describes the use process of the fecal immediate detection device of the present invention as follows:
after the user uses the sampling rod 4 to sample, when the excrement containing structure 42 is inserted into the scraping plate 31 inside the reagent tube 3, the excessive excrement sample is left above the scraping plate 31 (the orientation shown in fig. 2 is a reference), and does not enter the reagent below, so that sampling and quantitative measurement are realized, the guide protrusion 47 on the sampling rod 4 enters the first vertical groove 321 and is pushed to the bottom end of the first vertical groove 321 along the axial direction of the reagent tube 3, the positioning protrusion 48 is combined with the positioning groove 33 to form positioning, the sampling rod 4 is at the first position, after the sample is fully mixed with the reaction reagent, the user rotates the sampling rod 4 by a certain angle (for example, 45 degrees), the sampling rod 4 enters the top end of the second vertical groove 322 under the guidance of the first transverse groove 323, and is pushed downwards again along the axial direction of the reagent tube 3 towards the end where the excrement containing structure 42 is located, the sampling rod 4 is switched to the second position, the lower end of the sampling rod 4 passes through the sealing structure 36, the sample liquid in the reagent tube 3 flows into the flow channel 421 through the inlet of the flow channel 421 and then flows out from the outlet to the second area 101 below, enters the first area 100 under the guidance of the drainage surface 12 and is in contact with the detection test paper 2 in the first area 100 for chromatographic development, and the result can be directly observed through an outer window (for example, a wall body made of transparent material), and it is required to be specifically noted that the sample liquid above the inlet of the flow channel 421 flows into the second area 101 due to the sealing contact between the sealing structure 36 and the rod body 41, and the part below the inlet is reserved in the reagent tube 3, so that the quantitative control of the sample liquid in contact with the detection test paper 2 is realized.
It will be readily appreciated by those skilled in the art that the above advantageous ways can be freely combined and superimposed without conflict.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the invention. The foregoing is merely a preferred embodiment of the present invention, and it should be noted that it will be apparent to those skilled in the art that modifications and variations can be made without departing from the technical principles of the present invention, and these modifications and variations should also be regarded as the scope of the invention.
Claims (10)
1. An immediate fecal testing device for effecting transfer of a reagent by site switching, comprising:
a device main body (1), wherein the device main body (1) is provided with a sealing cavity (11), a detection test paper (2) is contained in the sealing cavity (11), and the sealing cavity (11) is provided with a first opening;
the reagent tube (3) is internally provided with a reaction reagent, the reagent tube (3) is inserted into the sealing cavity (11) through the first opening, the reagent tube (3) is a hollow tube body, the first end of the hollow tube body is provided with a sealing structure (36), and the second end of the hollow tube body is provided with a second opening;
the sampling rod (4) is in sealing connection with the second opening, the sampling rod (4) comprises a rod body (41), a first end of the rod body (41) is provided with a fecal accommodating structure (42), the fecal accommodating structure (42) is provided with a through-flow channel (421), the fecal accommodating structure (42) is provided with a first position and a second position, when the fecal accommodating structure (42) is in the first position, the fecal accommodating structure (42) is positioned in the reactant in the reagent tube (3), when the fecal accommodating structure (42) is in the second position, the fecal accommodating structure (42) can puncture the sealing structure (36) so that the reactant in the reagent tube (3) flows into the sealing cavity (11) through the through-flow channel (421), and the sealing structure (36) is in sealing contact with the rod body (41), the inlet of the through-flow channel (421) is positioned in the reagent tube (3), and the outlet of the through-flow channel (421) is positioned in the sealing cavity (11).
2. The fecal immediate detection device of claim 1 wherein,
the rod body (41) is provided with a sealing connection section, and the sealing connection section is in sealing connection with the second opening in a state that the excrement containing structure (42) is inserted into the reagent tube (3).
3. The fecal immediate detection device of claim 2 wherein,
a scraping plate (31) extending from outside to inside along the radial direction of the hollow tube body is also arranged in the hollow tube body, and the scraping plate (31) can scrape off excessive feces accommodated by the feces accommodating structure (42) in the process that the feces accommodating structure (42) is inserted into the reagent tube (3); and/or the side of the sealing connection section far away from the excrement containing structure (42) is provided with a handheld part (46).
4. The fecal immediate detection device of claim 1 wherein,
the reagent tube (3) is in buckling connection with the first opening; and/or the sealing structure (36) is a sealing flexible membrane.
5. The fecal immediate detection device according to claim 1, characterized in that the area of the sealing cavity (11) corresponding to the reagent tube (3) is a second area (101), the remaining area of the sealing cavity (11) is a first area (100), the detection test paper (2) is positioned in the first area (100), the bottom wall of the sealing cavity (11) is provided with a drainage surface (12) based on the orientation of the device in the use state, and the sample liquid flowing out of the reagent tube (3) flows from the second area (101) to the first area (100) under the action of the drainage surface (12).
6. The fecal immediate detection device according to claim 5, characterized in that it further comprises a test paper fixing plate (51) inserted in said first area (100), said detection test paper (2) being fixed on said test paper fixing plate (51).
7. The fecal immediate detection device according to claim 6, characterized in that the test paper fixing plate (51) has an assembly groove (511), wherein a desiccant (52) is assembled in the assembly groove (511).
8. The fecal immediate detection device according to claim 1, characterized in that the second opening of the reagent tube (3) is provided with an assembly matching structure, the assembly matching structure comprises a guiding groove constructed on the inner wall of the second opening, the guiding groove comprises a first vertical groove (321), a second vertical groove (322) and a first transverse groove (323) which are mutually arranged in parallel and are communicated with the bottom end of the first vertical groove (321) and the top end of the second vertical groove (322), the extending direction of the groove body of the first vertical groove (321) is consistent with the inserting direction of the sampling rod (4) and penetrates through the assembly matching structure to be far away from one side end surface of the sealing cavity (11), the sampling rod (4) is provided with a guiding protrusion (47), and the guiding protrusion (47) is matched with the guiding groove.
9. The fecal immediate detection device according to claim 8, characterized in that the assembly mating structure further comprises a positioning groove (33) configured on the inner wall of the second opening, the sampling rod (4) having a positioning protrusion (48) thereon, the positioning protrusion (48) being adapted to the positioning groove (33).
10. The fecal immediate detection device according to claim 9, characterized in that the guiding groove further comprises a second transversal groove (324), the second transversal groove (324) being parallel to the first transversal groove (323) and one end of the second transversal groove (324) being in communication with the second vertical groove (322), the second transversal groove (324) being adapted to the positioning protrusion (48).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211666941.XA CN116008532A (en) | 2022-12-22 | 2022-12-22 | Fecal immediate detection device for realizing transfer of reaction reagent through position switching |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211666941.XA CN116008532A (en) | 2022-12-22 | 2022-12-22 | Fecal immediate detection device for realizing transfer of reaction reagent through position switching |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116008532A true CN116008532A (en) | 2023-04-25 |
Family
ID=86029135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211666941.XA Pending CN116008532A (en) | 2022-12-22 | 2022-12-22 | Fecal immediate detection device for realizing transfer of reaction reagent through position switching |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN116008532A (en) |
-
2022
- 2022-12-22 CN CN202211666941.XA patent/CN116008532A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2020192711A1 (en) | Integrated device for medical sampling and testing | |
US4585623A (en) | Device for performing quantitative chemical and immunochemical assays | |
JP5400907B2 (en) | Needle-bulk interface for fluid analyzers | |
JP5400908B2 (en) | Fluidless interface for fluid analyzers | |
UA74071C2 (en) | Method of assay; device for the realization of the method (variants); assay cartridge (variants) | |
CN102072951B (en) | Reaction cassette, assay device, and assay method | |
JP2009521701A (en) | Fluid detection and control in fluid analyzers | |
CN109557295A (en) | Vim and vigour test method, vim and vigour test host, reagent packet and vim and vigour test card | |
CN101389965A (en) | Rapid test apparatus | |
CN114585442A (en) | Detection device and reception device | |
CN115902210A (en) | Device for detecting analyte in fluid sample | |
CN113945709A (en) | Urine test instrument, closestool and urine test method | |
CN113820480A (en) | Urine examination instrument | |
CN216284948U (en) | Sampling and detecting device | |
CN210427333U (en) | On-chip laboratory detection device | |
WO2021027082A1 (en) | Sample collection and detection device and method | |
CN219348877U (en) | Fecal immediate detection device for realizing transfer of reaction reagent through position switching | |
CN116008532A (en) | Fecal immediate detection device for realizing transfer of reaction reagent through position switching | |
CN219201612U (en) | Medical detection device capable of being integrated for in-vitro diagnosis | |
CN219109460U (en) | Accurate quantitative sampling device of blood | |
CN219348647U (en) | Fecal instant detection device | |
CN112795470B (en) | Detection device | |
CN211669206U (en) | Biological fluid detection device and detection system | |
CN210401430U (en) | Fecal occult blood detection device | |
CN112014553B (en) | Fecal occult blood detection device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |