CN115902281A - Automatic quantitative liquid injection method for blood culture bottle - Google Patents
Automatic quantitative liquid injection method for blood culture bottle Download PDFInfo
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- CN115902281A CN115902281A CN202211443532.3A CN202211443532A CN115902281A CN 115902281 A CN115902281 A CN 115902281A CN 202211443532 A CN202211443532 A CN 202211443532A CN 115902281 A CN115902281 A CN 115902281A
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- 239000007924 injection Substances 0.000 title claims abstract description 186
- 239000007788 liquid Substances 0.000 title claims abstract description 170
- 238000009640 blood culture Methods 0.000 title claims abstract description 97
- 238000000034 method Methods 0.000 title claims abstract description 35
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 17
- 230000007246 mechanism Effects 0.000 claims description 26
- 230000002572 peristaltic effect Effects 0.000 claims description 20
- 230000005540 biological transmission Effects 0.000 claims description 14
- 238000001802 infusion Methods 0.000 claims description 14
- 238000009434 installation Methods 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 13
- 238000001514 detection method Methods 0.000 claims description 6
- 239000003638 chemical reducing agent Substances 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 claims description 3
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- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
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- 230000035484 reaction time Effects 0.000 description 2
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- 238000012546 transfer Methods 0.000 description 2
- 238000011179 visual inspection Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010067268 Post procedural infection Diseases 0.000 description 1
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- 238000011002 quantification Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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Abstract
The invention discloses an automatic quantitative liquid injection method for a blood culture bottle, which comprises the following steps: firstly, placing a blood culture bottle on a rotating table, driving a liquid injection needle to descend to a preset height by a first power source, inserting the liquid injection needle into the blood culture bottle below, starting a liquid injection pump, and injecting a reagent into the blood culture bottle; secondly, the first power source drives the clamping unit to ascend and reset; thirdly, the second power source drives the rotating platform to rotate so that the next blood culture bottle rotates to a position right below the liquid injection needle, and quantitative liquid injection operation is carried out; and fourthly, repeating the first step to the third step to finish the continuous automatic quantitative operation of a plurality of blood culture bottles. According to the invention, the reagent is automatically and quantitatively injected into the blood culture bottle by using the liquid injection pump, so that the liquid injection efficiency is improved, and the liquid injection precision is also improved; the first power source can realize the plugging and unplugging of the liquid injection needle without manual plugging and unplugging, so that the operation safety is improved; the blood culture bottles are driven to rotate by the second power source, continuous quantitative liquid injection of the blood culture bottles is achieved, and working efficiency is improved.
Description
Technical Field
The invention relates to the field of blood culture, in particular to an automatic quantitative liquid injection method for a blood culture bottle.
Background
Blood culture is widely used for the detection processes such as high fever and persistent fever of children, postoperative infection and the like, a blood culture bottle is usually adopted for culture, a blood sample is added into the culture bottle, then a reagent required by bacterial growth is added, the whole operation process requires sterility and can not enter air, and blood culture scrapping can be caused once air or mixed bacteria enter the air. Thus, the priming operation is required to be aseptic and air cannot be introduced during the blood culture. In addition, the amount of injected reagent is one of the important indexes affecting the blood culture result, and when the amount of reagent in the bottle is too large, the amount of bacteria participating in the culture is increased, that is, the amount of bacteria participating in the culture is increased within a predetermined reaction time, so that a false positive report is generated; when the amount of reagent in the flask is small, the amount of bacteria participating in culture in a given reaction time is reduced, and a false negative report is generated. Therefore, before the blood culture bottle leaves the factory, the function of the blood culture bottle is required to be verified by injecting culture reagents into the blood culture bottle in a fixed amount; in the subsequent blood culture process, reagents are also required to be injected into the culture bottle in a fixed amount to obtain a desired culture result.
At present, in the blood culture process, the common culture reagent injection mode is manual injection, namely, the reagent is manually injected into a blood culture bottle by a syringe manually, and the injection amount is determined by visual inspection through scale marks on the syringe. However, when the injector is used for manual injection, the operator is injured if the operation is improper, and even the wound of the operator is polluted by the reagent, and the manual injection efficiency is low, so that the requirement of rapid quantification of a large number of blood culture bottles cannot be met; in addition, the operator judges the injection amount by visual inspection in the injection process, so that the error is large, the precision is low, and the determination of the culture reagent amount in the blood culture bottle is influenced.
Disclosure of Invention
In view of the above, the invention provides an automatic quantitative liquid injection method for a blood culture bottle, which realizes continuous liquid injection of a plurality of blood culture bottles, has high liquid injection efficiency and high liquid injection precision, is helpful for manufacturers to quickly determine the reagent injection amount of the blood culture bottle, and is also suitable for blood culture of a blood culture detection mechanism.
In order to realize the purpose, the invention adopts the following technical scheme:
the invention relates to an automatic quantitative liquid injection method for a blood culture bottle, which adopts a special quantitative injection device for the blood culture bottle, wherein the quantitative injection device for the blood culture bottle comprises a base; and also comprises
The mounting frame body is provided with a first mounting unit which is vertically arranged, a second mounting unit and a third mounting unit which are horizontally arranged, and the second mounting unit and the third mounting unit are arranged on the first mounting unit at intervals;
the quantitative injection system is provided with a liquid storage container, a liquid injection pump and a liquid injection needle which are sequentially connected through a liquid injection pipeline, the liquid injection pump is arranged on the second mounting unit, and the liquid storage container is arranged on the third mounting unit;
the lifting mechanism is arranged on the first mounting unit and is provided with a first power source and a clamping unit for fixing the liquid injection needle, and the clamping unit is in transmission connection with the first power source; and
the culture bottle bearing mechanism is arranged on the base and is provided with a second power source and a rotating platform which is driven by the second power source to rotate and is used for bearing the culture bottle;
the detection unit is provided with a first sensor arranged on the installation frame body and a second sensor used for recording the liquid injection times of the liquid injection needle, and a trigger piece matched with the first sensor is arranged on a lifting piece of the lifting mechanism;
the electric control system is provided with a control unit, the signal input end of the control unit is respectively connected with the signal output ends of the first sensor and the second sensor, and the control output end of the control unit is respectively connected with the control input ends of the first power source and the second power source;
the automatic quantitative liquid injection method for the blood culture bottle comprises the following steps:
firstly, placing a blood culture bottle on a rotating table, sending an injection instruction to a first power source by a control unit, receiving the instruction of the control unit by the first power source, driving an injection needle to descend to a preset height and inserting the injection needle into the blood culture bottle below; after the liquid injection needle is in place, the control unit controls the liquid injection pump to start and injects a reagent into the blood culture bottle;
secondly, after liquid injection is finished, the control unit controls the liquid injection pump to stop working, and respectively sends a rotation instruction to the second power source and a reset instruction to the first power source, the first power source drives the clamping unit to ascend and reset, the first sensor detects a signal of the trigger sheet and transmits the signal to the control unit, and the control unit generates an instruction that the clamping unit reaches an original position according to the acquired information and controls the lifting mechanism to stop working;
thirdly, the second power source receives a rotation instruction of the control unit to drive the rotating platform to rotate by a preset angle, so that the next blood culture bottle rotates to a position right below the liquid injection needle, and the first step and the second step are repeated to finish the automatic quantitative liquid injection operation of the second blood culture bottle;
fourthly, repeating the first step to the third step to finish the continuous automatic quantitative operation of a plurality of blood culture bottles;
in the process of reciprocating the clamping unit, the second sensor acquires a reciprocating signal of the clamping unit and transmits the reciprocating signal to the control unit, the control unit generates a reciprocating frequency and a liquid injection frequency according to the received reciprocating signal of the clamping unit, when the liquid injection frequency exceeds a preset value, the control unit generates an alarm signal and sends the alarm signal to the alarm unit, and the alarm unit gives an alarm.
In the scheme, the reagent is automatically and quantitatively injected into the blood culture bottle by using the injection pump, so that the injection efficiency is improved, and the injection precision is also improved; in addition, in the liquid injection process, the lifting mechanism can drive the liquid injection needle to lift, so that the liquid injection needle can be plugged and unplugged without manual plugging and unplugging, and the operation safety is improved; moreover, the blood culture bottle is driven to rotate by the second power source during liquid injection, so that an operator can conveniently take away the blood culture bottle after quantitative liquid injection in time and place another blood culture bottle to be injected with liquid, continuous quantitative liquid injection of a plurality of blood culture bottles is realized, and the working efficiency is improved;
according to the invention, the second sensor and the control unit are used for recording the liquid injection times of the liquid injection needle, and when the liquid injection times exceed the preset value, the control unit generates an alarm signal, so that an alarm of the control unit gives an alarm to remind an operator to replace the liquid injection needle in time, thereby ensuring normal liquid injection.
Preferably, the base is an electronic control base, the control unit is arranged in the electronic control base, and the alarm unit (the alarm unit can be a buzzer or a display lamp or the combination of the buzzer and the display lamp) is arranged on the electronic control base. More preferably, the electronic control base is further provided with a control panel with a display screen and an emergency stop switch. When the device works, the liquid injection amount can be set through the control panel; when an emergency occurs, the liquid injection operation can be stopped suddenly through the sudden stop switch.
In a preferred embodiment of the present invention, the infusion pump is a peristaltic pump, and a control input end of the infusion pump is connected with a control output end of the control unit. During operation, the control unit can automatically control the starting and closing conditions of the liquid injection pump, so that automatic quantitative liquid injection of each blood culture bottle is realized, and the liquid injection accuracy is improved.
In another preferred embodiment of the present invention, the infusion pump has a foot switch for controlling the on and off of the infusion pump. When the device works, the opening and closing of the liquid injection pump can be controlled by the pedal switch.
Preferably, the first power source is a screw stepping motor, or a first motor and a transmission screw driven by the first motor, or a screw driven by a synchronous belt transmission mechanism, or an electric push rod, or a linear motor; the second power source is a second motor, or a motor reducer with a reduction ratio, or a gear transmission mechanism, or a chain transmission mechanism, or a belt transmission mechanism. In actual installation, the first power source and the second power source can be determined according to actual conditions (such as installation space, cost and the like). More preferably, the first power source is a linear motor, and the lifting member is a sliding block of the linear motor. In the invention, the first power source is preferably a linear motor with a guide rail, so that the linear motion track and the motion precision of the raw clamping unit are ensured. In the present invention, the second power source is preferably a second motor.
Preferably, the first mounting unit is a vertical beam vertically arranged, the second mounting unit is a first cross beam horizontally arranged on the vertical beam, and the third mounting unit is a second cross beam horizontally arranged on the vertical beam. The second cross beam is located above the first cross beam, and the liquid storage container is located above the injection pump.
In a preferred embodiment of the present invention, a silicone hose with a connection joint is disposed on the peristaltic pump, the liquid injection pipeline is a liquid injection hose, and the liquid injection hose connects the liquid storage container, the silicone hose and the liquid injection needle together. More preferably, the liquid injection hose is a disposable infusion apparatus with a luer connector. The invention adopts the disposable sterile infusion apparatus with the luer connector to connect the liquid storage container, the peristaltic pump and the liquid injection needle together, is cheap, easy to obtain and sterile, is simple and convenient to replace, is convenient to operate and reduces the automatic liquid injection cost of the blood culture bottle; in addition, the luer connector and the liquid injection pipeline are combined to effectively ensure the air tightness, the water tightness and certain negative pressure in the liquid injection process, ensure the negative pressure liquid injection and avoid the gas entering the culture bottle. In addition, the liquid injection hose can be also provided with accessories such as an infusion heater, an infusion bag and the like.
Compared with the prior art, the invention only needs an operator to place the culture bottle on the rotating platform or take the blood culture bottle on the rotating platform away, does not need to manually insert and pull the liquid injection needle, can ensure quantitative liquid injection of each blood culture bottle, realizes continuous liquid injection and improves the liquid injection efficiency. Specifically, the method comprises the following steps:
the liquid injection needle is driven to lift by the lifting mechanism, so that the liquid injection needle is plugged and unplugged without manual plugging and unplugging, and the operation safety is improved; in addition, reagents are automatically and quantitatively injected into the blood culture bottle by using the injection pump during injection, so that the injection efficiency is improved, and the injection precision is also improved;
in the liquid injection process, the blood culture bottle is driven to rotate by the second power source, so that an operator can conveniently take the blood culture bottle after quantitative liquid injection in time and place another blood culture bottle to be injected with liquid, continuous quantitative liquid injection of a plurality of blood culture bottles is realized, and the working efficiency is improved.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a circuit diagram of the metered dose injection system of the present invention.
Fig. 3 is a schematic block diagram of the circuit of the present invention.
FIG. 4 is a schematic view of the connection of the injection needle and the holding unit according to the present invention.
Fig. 5 isbase:Sub>A schematic view of the directionbase:Sub>A-base:Sub>A of fig. 4.
Detailed Description
The following describes embodiments of the present invention in detail with reference to the drawings, which are implemented on the premise of the technical solution of the present invention, and detailed embodiments and specific operation procedures are provided, but the scope of the present invention is not limited to the following embodiments.
It should be noted that in the following description of the embodiments, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" when they are presented are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; either directly or indirectly through intervening media, or may be interconnected between two elements. The specific meanings of the above-mentioned terms in the present invention can be understood by those skilled in the art through specific situations.
In addition, it should be noted that in the following description of the embodiments, the terms "front", "back", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be configured in a specific orientation, and operate, and thus, should not be construed as limiting the present invention.
The invention provides an automatic quantitative liquid injection method for blood culture bottles, which realizes automatic injection of culture liquid in each blood culture bottle, improves liquid injection accuracy and liquid injection efficiency, and liberates two hands.
Specifically, the automatic quantitative liquid injection method for the blood culture bottle adopts a special quantitative injection device for the blood culture bottle. As can be seen from fig. 1-2, the quantitative injection device for blood culture bottles comprises a base 1, a mounting frame, a quantitative injection system, a lifting mechanism, a culture bottle supporting mechanism, an electric control system and a detection assembly;
the installation support body sets up in one side of base 1, and it has the first installation unit of vertical setting (being perpendicular roof beam 2.1 promptly) and the second installation unit (being first crossbeam 2.2) and the third installation unit (being second crossbeam 2.3) of level setting on perpendicular roof beam 2.1, and second crossbeam 2.3 is located first crossbeam 2.2's top. During actual installation, the vertical beam 2.1 is preferably fixedly installed on the base 1, and the base 1 can be moved to realize integral transfer, so that the transfer is convenient;
the quantitative injection system comprises a liquid storage container 3.1, an injection pump 3.2 (the injection pump 3.2 is preferably a peristaltic pump) and an injection needle 3.3 (a commercially available infusion needle or an injection needle is adopted) which are sequentially connected through an injection pipeline, wherein the injection pump 3.2 is arranged on a first cross beam 2.2, and the liquid storage container 3.1 is arranged on a second cross beam 2.3;
the lifting mechanism is provided with a first power source arranged on the first mounting unit, a sliding piece and a clamping unit (namely a clamping unit 4) for fixing the liquid injection needle 3.3, and the clamping unit 4 is connected with the first power source through the sliding piece; the up-and-down reciprocating of the lifting mechanism realizes the automatic plugging and unplugging of the liquid injection needle 3.3 on the soft plug of the blood culture bottle;
the culture bottle supporting mechanism is arranged on the base 1 and is provided with a second power source 5.3 and a rotating platform 5.1 which is driven by the second power source 5.3 to rotate and is used for supporting the culture bottle; every time liquid is injected, the second power source 5.3 drives the rotating platform 5.1 to rotate by a preset angle, so that the other blood culture bottle to be injected is rotated to be right below the liquid injection needle 3.3, the continuous liquid injection of the blood culture bottle is further realized, and the working efficiency is improved;
the detection assembly comprises a first sensor 7.1 (preferably a groove-type photoelectric switch, the installation height of which is the initial height) and a second sensor 7.3 which are arranged on one side of the vertical beam 2.1, a trigger piece 7.2 matched with the groove of the first sensor 7.1 is arranged on the sliding piece, and when the trigger piece 7.2 triggers the first sensor 7.1 along with the rising of the sliding block 6.2, the sliding block 6.2 and the clamping unit 4 are indicated to rise to the initial height; a second sensor 7.3, preferably an infrared sensor, is arranged on the first cross beam 2.2 near the vertical beam 2.1. In the automatic liquid injection process, the reciprocating times of the sliding piece or the lifting unit are detected through the second sensor 7.3, and the liquid injection times of the liquid injection needle 3.3 are determined;
the electric control system is provided with a control unit (namely a single chip microcomputer) arranged in the base and an alarm unit (namely an alarm and a preferable buzzer) arranged on the base (namely the electric control base), the signal input end of the single chip microcomputer is respectively connected with the signal output ends of the first sensor 7.1 and the second sensor 7.3, the control output end of the single chip microcomputer is respectively connected with the linear motor 6.1, the second power source 5.3 and the control input end of the peristaltic pump, the signal output end of the single chip microcomputer is connected with the signal input end of the alarm, the first sensor 7.1 and the second sensor 7.3 transmit detected information to the controller, the highest rising position of the sliding block 6.2, the injection times and the rotation of the rotating table 5.1 are determined through the controller, further quantitative injection of each blood culture bottle on the rotating table 5.1 is realized, the automatic continuous injection of a plurality of blood culture bottles is improved, and the injection efficiency is improved.
In actual installation, as can be known by referring to fig. 2, the liquid injection pipeline is a disposable output device, and includes a first flexible pipe 3.4 communicated with the liquid storage container 3.1, and a second flexible pipe 3.5 communicated with the liquid injection needle 3.3 (a commercially available liquid injection needle or an injection needle is selected), and the first flexible pipe 3.4 and the second flexible pipe 3.5 are both connected with a peristaltic pump flexible pipe 3.6 (generally, a silicone tube) of the peristaltic pump through paired luer connectors. The invention adopts the disposable sterile infusion apparatus with the luer connector to connect the liquid storage container, the peristaltic pump and the liquid injection needle together, is cheap, easy to obtain (the cost is as low as below two yuan), is sterile, is simple and convenient to replace and convenient to operate, and reduces the automatic liquid injection cost of the blood culture bottle; in addition, the luer connector and the liquid injection pipeline are combined to effectively ensure the air tightness, the water tightness and certain negative pressure in the liquid injection process, ensure the negative pressure liquid injection and avoid the gas entering the culture bottle. In addition, the liquid injection hose can be also provided with accessories such as an infusion heater, an infusion bag and the like.
It can be known by combining fig. 1 that the linear electric motor 6.1 that has the guide rail is preferred to elevating system's first power supply, linear electric motor 6.1 has one along the gliding elevating part of guide rail (sliding block 6.2 promptly), clamping unit (clamping unit 4 promptly) is fixed on sliding block 6.2, linear electric motor 6.1 drives clamping unit 4 up-and-down reciprocating motion through sliding block 6.2, can not only realize the reciprocal lift from top to bottom of annotating liquid needle 3.3, can also guarantee the motion precision of annotating liquid needle 3.3, and then satisfy the plug demand when blood culture bottle ration annotates liquid.
In actual installation, the linear motor 6.1 in this embodiment may be replaced by other power sources capable of realizing linear lifting of the clamping unit 4, such as a lead screw stepping motor, a lead screw in transmission connection with the motor, a lead screw driven by a synchronous belt transmission mechanism, an air cylinder, a hydraulic cylinder, an electric push rod, and the like.
The automatic quantitative liquid injection method for the blood culture bottle comprises the following steps of:
firstly, hanging a liquid storage container 3.1 on a second cross beam 2.3, fixing a pump body of a peristaltic pump on a first cross beam 2.2, inserting an inlet end of a first hose 3.4 into the liquid storage container 3.1, then respectively inserting the first hose 3.4 and a second hose 3.5 on a hose 3.6 of the peristaltic pump, and then clamping a liquid injection needle 3.3 on a clamping unit 4 to finish the installation of a quantitative injection system;
secondly, setting the liquid injection flow and time of the blood culture bottle according to the specification of the blood culture bottle, and uniformly placing four blood culture bottles (five or six bottles, etc.) on a rotating table 5.1 at intervals in the circumferential direction;
the single chip microcomputer sends a liquid injection instruction to the linear motor 6.1, the linear motor 6.1 drives the sliding block 6.2 to descend so as to drive the clamping unit 4 and the liquid injection needle 3.3 to descend, and the lower part of the liquid injection needle 3.3 penetrates through a soft plug of the blood culture bottle; the single chip microcomputer sends a liquid injection instruction to the peristaltic pump, and the peristaltic pump is used for accurately injecting liquid into the blood culture bottle;
thirdly, after the liquid injection is finished, the single chip microcomputer controls the peristaltic pump to stop working, a reset instruction is sent to the linear motor 6.1, the sliding block 6.2 of the linear motor 6.1 rises to reset, the needle head of the liquid injection needle 3.3 is pulled out of the blood culture bottle and rises synchronously with the sliding block 6.2, and when the trigger piece 7.2 on the sliding block 6.2 moves into the first sensor 7.1, the single chip microcomputer controls the linear motor 6.1 to stop working;
meanwhile, the single chip microcomputer sends a rotation instruction to the second power source 5.3, the second power source 5.3 drives the rotating platform 5.1 to rotate by a preset angle (if the rotating platform only has four culture positions, the second power source rotates by 90 degrees every time; similarly, if the rotating platform has six culture positions in the circumferential direction, the second power source rotates by 60 degrees every time), so that the other blood culture bottle rotates to be right below the liquid injection needle 3.3, and the second step is repeated to complete liquid injection of the second culture bottle;
so repeatedly, can realize the liquid operation is annotated to the automation in succession ration of a plurality of blake bottles, and whole only need the staff can take the blood culture bottle after accomplishing the ration and annotate liquid away and supply the new blood culture bottle of waiting to annotate the liquid, need not the manual work and annotate liquid, and degree of automation is high, can realize the operation of annotating liquid in succession of blood culture bottle in batches, has improved work efficiency.
In the liquid injection process, the liquid injection needle 3.3 is a consumable material and can be damaged after being used for multiple times, and the singlechip records the round trip times of the clamping unit 4 through the second sensor 7.3 to determine the liquid injection times of the liquid injection needle 3.3; when the number of times of using the liquid injection needle 3.3 exceeds 20 (or 25, 30 and the like), the alarm gives an alarm to prompt and remind a worker to replace the second hose 3.5 and the liquid injection needle 3.3 so as to ensure normal operation of liquid injection.
When the actual installation, blake bottle supporting mechanism is still including fixing support 5.2 on base 1, and second power supply 5.3 is for fixing the motor speed reducer on support 5.2, and revolving stage 5.1 is fixed on the motor shaft of motor, and revolving stage 5.1 is used for a plurality of blood blake bottle F of placing along its circumferencial direction of bearing, and then realizes blood blake bottle F's continuous liquid operation of annotating, has improved and has annotated liquid efficiency, specifically as shown in fig. 1.
In order to facilitate the operation, the electric control base is further provided with a control panel 7.4 (see figure 1) with a display screen and an emergency stop switch, the liquid injection flow and the liquid injection time of each blood culture bottle can be set through the control panel 7.4, the automatic injection of each blood culture bottle is ensured, manual auxiliary operation is not needed, and the accuracy is high. When an emergency occurs, the emergency stop of the liquid injection operation can be realized through the emergency stop switch, so that the sample and the device are protected.
As can be seen from fig. 4 and 5, the clamping unit 4 includes a first fixing block 4.1 fixed on the sliding block 6.2 and a second fixing block 4.2 fixed on the first fixing block 4.1 by bolts, and an arc-shaped snap ring for clamping the liquid injection needle 3.3 is arranged in a gap between the first fixing block 4.1 and the second fixing block 4.2. When in use, the upper part of the liquid injection needle 3.3 can be clamped in the arc-shaped clamping ring 4.3, so that the liquid injection needle 3.3 is fixed.
In other embodiments of the invention, the peristaltic pump is provided with a foot switch for controlling the opening and closing of the peristaltic pump, and the opening and closing of the foot switch are controlled by a driver of the peristaltic pump, so that flexible control of the peristaltic pump is realized. When the device leaves a factory, whether the foot switch is equipped or not is selected according to the requirements of a user.
Finally, it should be emphasized that the above-described embodiments are merely preferred embodiments of the present invention, and not limitations of the invention are intended to be imposed on the scope of the present invention, and although the invention has been described in detail with reference to the above-described embodiments, it will be apparent to those skilled in the art that modifications and equivalents may be made to the embodiments described in the foregoing embodiments without inventive faculty, or that equivalents may be substituted for some of the features. Therefore, any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. An automatic quantitative liquid injection method for a blood culture bottle is characterized by comprising the following steps: a special blood culture bottle quantitative injection device is adopted, and the blood culture bottle quantitative injection device comprises a base; also comprises
The mounting frame body is provided with a first mounting unit which is vertically arranged, a second mounting unit and a third mounting unit which are horizontally arranged, and the second mounting unit and the third mounting unit are arranged on the first mounting unit at intervals;
the quantitative injection system is provided with a liquid storage container, a liquid injection pump and a liquid injection needle which are sequentially connected through a liquid injection pipeline, the liquid injection pump is arranged on the second mounting unit, and the liquid storage container is arranged on the third mounting unit;
the lifting mechanism is arranged on the first mounting unit and is provided with a first power source and a clamping unit for fixing the liquid injection needle, and the clamping unit is in transmission connection with the first power source; and
the culture bottle bearing mechanism is arranged on the base and is provided with a second power source and a rotating platform which is driven by the second power source to rotate and is used for bearing the culture bottle;
the detection unit is provided with a first sensor arranged on the installation frame body and a second sensor used for recording the liquid injection times of the liquid injection needle, and a trigger piece matched with the first sensor is arranged on a lifting piece of the lifting mechanism;
the electric control system is provided with a control unit and an alarm unit, the signal input end of the control unit is respectively connected with the signal output ends of the first sensor and the second sensor, and the control output end of the control unit is respectively connected with the control input ends of the first power source and the second power source;
the automatic quantitative liquid injection method for the blood culture bottle comprises the following steps:
firstly, placing a blood culture bottle on a rotating table, sending an injection instruction to a first power source by a control unit, receiving the instruction of the control unit by the first power source, driving an injection needle to descend to a preset height and inserting the injection needle into the blood culture bottle below; after the liquid injection needle is in place, the control unit controls the liquid injection pump to start and injects a reagent into the blood culture bottle;
secondly, after liquid injection is finished, the control unit controls the liquid injection pump to stop working, and respectively sends a rotation instruction to the second power source and a reset instruction to the first power source, the first power source drives the clamping unit to ascend and reset, the first sensor detects a signal of the trigger sheet and transmits the signal to the control unit, and the control unit generates an instruction that the clamping unit reaches an original position according to the acquired information and controls the lifting mechanism to stop working;
thirdly, the second power source receives a rotation instruction of the control unit to drive the rotating platform to rotate by a preset angle, so that the next blood culture bottle rotates to a position right below the liquid injection needle, and the first step and the second step are repeated to finish the automatic quantitative liquid injection operation of the second blood culture bottle;
fourthly, repeating the first step to the third step to finish the continuous automatic quantitative operation of a plurality of blood culture bottles;
in the process of reciprocating the clamping unit, the second sensor acquires a reciprocating signal of the clamping unit and transmits the reciprocating signal to the control unit, the control unit generates a reciprocating frequency and a liquid injection frequency according to the received reciprocating signal of the clamping unit, when the liquid injection frequency exceeds a preset value, the control unit generates an alarm signal and sends the alarm signal to the alarm unit, and the alarm unit gives an alarm.
2. The automatic quantitative filling method for the blood culture bottle according to claim 1, wherein: the liquid injection pump is a peristaltic pump, and the control input end of the peristaltic pump is connected with the control output end of the control unit.
3. The automatic quantitative filling method for the blood culture bottle according to claim 2, characterized in that: the liquid injection pump is also provided with a foot switch for controlling the opening and closing of the liquid injection pump.
4. The automatic quantitative filling method for the blood culture bottle according to claim 2 or 3, characterized in that: the base is an electronic control base, and the control unit is arranged in the electronic control base.
5. The automatic quantitative filling method for the blood culture bottle according to claim 1, wherein: the first power source is a lead screw stepping motor, or a first motor and a transmission lead screw driven by the first motor, or a lead screw driven by a synchronous belt transmission mechanism, or an electric push rod, or a linear motor;
the second power source is a second motor, or a motor reducer with a reduction ratio, or a gear transmission mechanism, or a chain transmission mechanism, or a belt transmission mechanism.
6. The automatic quantitative filling method for the blood culture bottle according to claim 2, characterized in that: the first power source is a linear motor, and the lifting piece is a sliding block of the linear motor.
7. The automatic quantitative filling method for the blood culture bottle according to claim 1, wherein: the first mounting unit is a vertical beam vertically arranged, the second mounting unit is a first cross beam horizontally arranged on the vertical beam, and the third mounting unit is a second cross beam horizontally arranged on the vertical beam.
8. The automatic quantitative filling method for the blood culture bottle according to claim 2, characterized in that: be provided with the silica gel hose that has attach fitting on the peristaltic pump, annotate the liquid pipeline for annotating the liquid hose, it will to annotate the liquid hose stock solution container, silica gel hose and annotate the liquid needle and link together.
9. The automatic quantitative infusion method for the haemoculture bottle according to claim 8, characterized in that: the liquid injection hose and the liquid injection needle are disposable infusion sets with luer connectors.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211443532.3A CN115902281A (en) | 2022-11-18 | 2022-11-18 | Automatic quantitative liquid injection method for blood culture bottle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211443532.3A CN115902281A (en) | 2022-11-18 | 2022-11-18 | Automatic quantitative liquid injection method for blood culture bottle |
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| Publication Number | Publication Date |
|---|---|
| CN115902281A true CN115902281A (en) | 2023-04-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211443532.3A Pending CN115902281A (en) | 2022-11-18 | 2022-11-18 | Automatic quantitative liquid injection method for blood culture bottle |
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| Country | Link |
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| CN (1) | CN115902281A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117429848B (en) * | 2023-12-18 | 2024-03-08 | 建诺为生物技术(江苏)有限公司 | Cell culture bottle production conveyor |
-
2022
- 2022-11-18 CN CN202211443532.3A patent/CN115902281A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117429848B (en) * | 2023-12-18 | 2024-03-08 | 建诺为生物技术(江苏)有限公司 | Cell culture bottle production conveyor |
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Country or region after: China Address after: 450016 No.199, Jingkai 15th Street, Zhengzhou Economic and Technological Development Zone, Henan Province Applicant after: AUTOBIO LABTEC INSTRUMENTS Co.,Ltd. Address before: No. 199, 15th Street, economic and Technological Development Zone, Zhengzhou City, Henan Province Applicant before: AUTOBIO LABTEC INSTRUMENTS Co.,Ltd. Country or region before: China |