CN115876513B - Intracardiac experiment tissue grinds sampling device - Google Patents
Intracardiac experiment tissue grinds sampling device Download PDFInfo
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- CN115876513B CN115876513B CN202310077104.1A CN202310077104A CN115876513B CN 115876513 B CN115876513 B CN 115876513B CN 202310077104 A CN202310077104 A CN 202310077104A CN 115876513 B CN115876513 B CN 115876513B
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- 238000005070 sampling Methods 0.000 title claims abstract description 47
- 238000002474 experimental method Methods 0.000 title claims abstract description 11
- 238000000227 grinding Methods 0.000 claims abstract description 126
- 238000007789 sealing Methods 0.000 claims description 26
- 239000007788 liquid Substances 0.000 claims description 19
- 238000001179 sorption measurement Methods 0.000 claims description 9
- 239000012530 fluid Substances 0.000 description 17
- 239000004744 fabric Substances 0.000 description 14
- 239000007787 solid Substances 0.000 description 14
- 238000000926 separation method Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- 239000011550 stock solution Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 238000005498 polishing Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000010297 mechanical methods and process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000002306 biochemical method Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
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Abstract
The invention discloses an intracardiac experimental tissue grinding sampling device which comprises a grinding base, wherein the top of the grinding base is fixedly connected with a grinding support, the top of the grinding support is fixedly connected with a grinding device, and the part of the top of the grinding base, which is positioned below the grinding device, is fixedly connected with a sampling device; the grinding device includes: the grinding device comprises a fixed base, a grinding device and a lifting device, wherein the fixed base is provided with a circular disc-shaped structure and a grinding groove arranged at the top of the fixed base, the top of the fixed base is fixedly connected with a connecting bracket, and one side of the connecting bracket is fixedly connected with a lifting rod; the invention relates to the technical field of tissue grinding and sampling, in particular to a grinding head, which is provided with a spherical structure and a driving motor arranged above the grinding head, wherein the top of the driving motor is fixedly connected with the movable end of a lifting rod. This intracardiac experiment tissue grinds sampling device, pull out plug-in structure makes the dismouting more convenient, and the convenience is changed and is cleared up the grinding head.
Description
Technical Field
The invention relates to the technical field of tissue grinding and sampling, in particular to an intracardiac experimental tissue grinding and sampling device.
Background
The grinding and sampling are convenient and efficient sampling methods, grinding the picked sample by a grinder, transferring the ground sample to an ultra-clean bench for detection and observation, and grinding biological tissues to generate samples in two forms of liquid and solid, wherein in the biotechnology and medical fields, the cell or tissue is often required to be crushed so as to extract various substances required, and the cell or tissue crushing methods comprise a mechanical method, a physical method, a chemical method, a biochemical method and the like, wherein the mechanical method mainly breaks tissue cells by the action of a grinding head, and common devices include a tissue pestle, a mortar grinder, an ultrasonic crusher and the like.
The grinding device used at present is generally inconvenient to separate and sample liquid and solid, and after the sampling is finished, the sample needs to be separated again, so that the grinding head is inconvenient to use and inconvenient to clean.
Disclosure of Invention
In order to achieve the above purpose, the invention is realized by the following technical scheme: the intracardiac experimental tissue grinds sampling device, including grinding the base, grind base top fixedly connected with grinds the support, grind support top fixedly connected with grinder, grind the part that the base top is located the grinder below and be connected with sampling device fixedly;
the grinding device includes:
the grinding device comprises a fixed base, a grinding device and a lifting device, wherein the fixed base is provided with a circular disc-shaped structure and a grinding groove arranged at the top of the fixed base, the top of the fixed base is fixedly connected with a connecting bracket, and one side of the connecting bracket is fixedly connected with a lifting rod;
the grinding head is provided with a spherical structure and a driving motor arranged above the grinding head, and the top of the driving motor is fixedly connected with the movable end of the lifting rod;
the positioning seat is provided with a circular disc-shaped structure and a positioning groove arranged at the top of the positioning seat, the bottom of the inner wall of the positioning groove is fixedly connected with an adsorption magnet, the bottom of the positioning seat is fixedly connected with the top of the grinding head, a driving shaft of the driving motor extends to the inside of the positioning groove and is in sliding connection with the inner wall of the positioning groove, and the pulling-inserting structure is convenient to assemble and disassemble and convenient to replace and clean the grinding head.
Preferably, the bottom of the fixed base is fixedly connected with the top of the grinding support, and the shape of the grinding head is matched with the shape of the grinding groove.
Preferably, a magnet block matched with the adsorption magnet is fixedly connected to the driving shaft of the driving motor, a limiting sliding groove is formed in the inner wall of the positioning groove, and a limiting sliding bar matched with the limiting sliding groove is fixedly connected to the side face of the driving shaft of the driving motor.
Preferably, unable adjustment base includes the base body, the grinding groove is seted up at base body top, the first screen cloth of grinding groove inner wall bottom fixedly connected with, the holding tank has been seted up to base body bottom, holding tank inner wall fixedly connected with arc backup pad, the part fixedly connected with second screen cloth that the holding tank inner wall is located arc backup pad top, sealed spout has been seted up at base body top, sealed spout inner wall sliding connection has the closing plate, run through on the closing plate and fixedly connected with charging connector for can separate solid and liquid voluntarily after grinding, make things convenient for subsequent experiment to use, accessible atmospheric pressure accelerates the speed that the tissue liquid passes through the screen cloth simultaneously, improves separation speed, and can make the tissue liquid more thoroughly of separation between the piece after grinding.
Preferably, the bottom of the base body is fixedly connected with the top of the grinding support, and the top of the base body is fixedly connected with the bottom of the connecting support.
Preferably, the grinding groove is formed in the sealing sliding groove, a sealing gasket is arranged between the sealing plate and the sealing sliding groove, and the mesh diameter of the second screen is smaller than that of the first screen.
Preferably, the sampling device comprises an outer sleeve, outer sleeve inner wall sliding connection has the inner tube, inner tube inner wall sliding connection has the sampling tube, the feed liquor hole has all been seted up to outer sleeve, inner tube and sampling tube side, sampling tube bottom intercommunication has the stock solution ball, sampling tube top runs through outer sleeve and inner tube and fixedly connected with storage shell, the fretwork hole has been seted up to the storage shell side, conveniently carries out the sample to the tissue piece of solid and the tissue liquid of liquid simultaneously to can collect when grinding, sampling efficiency is higher, also can separately collect solid and liquid simultaneously, facilitates subsequent use.
Preferably, the top of the outer sleeve penetrates through the arc-shaped supporting plate and the first screen mesh and is fixedly connected with the arc-shaped supporting plate and the first screen mesh.
Preferably, the shape of the storage shell is matched with the shape of the inner wall of the inner cylinder, and the liquid inlet hole extends to the upper part of the arc-shaped supporting plate.
The invention provides an intracardiac experimental tissue grinding and sampling device. The beneficial effects are as follows:
1. this intracardiac experiment tissue grinds sampling device is provided with grinder, place the biological tissue during the use inside grinding the groove, drive the grinding head of driving motor below through the lifter and insert inside the grinding groove, then drive the grinding head through driving motor and rotate can grind the inside tissue of grinding the groove, when grinding the end need wash the grinding head, directly with grinding head and positioning seat pull out from driving motor's drive shaft can, fixed the grinding head through the adsorption force between the inside absorption magnetite of positioning groove and the epaxial magnet piece of driving motor's drive, pull out plug-in structure and make easy dismounting, the convenience is changed and is cleared up the grinding head.
2. This intracardiac experiment tissue grinds sampling device is provided with unable adjustment base, after grinding the inside tissue of grinding groove, less piece and tissue fluid pass first screen cloth and enter into the second screen cloth top, and tissue fluid rethread second screen cloth enters into arc backup pad top, can accomplish the separation of piece and tissue fluid for can separate solid and liquid voluntarily after grinding, make things convenient for follow-up experiment to use.
3. This intracardiac experiment tissue grinds sampling device is provided with sealed spout and closing plate, after grinding, can slide into sealed spout inside with the closing plate, then aerify to grinding inslot portion through the charging connector, and the inside atmospheric pressure of grinding inslot increases for the atmospheric pressure of second screen cloth top increases, can accelerate the speed that the tissue liquid passed through the screen cloth through the atmospheric pressure, improves separation rate, and can make the tissue liquid more thoroughly of separation between the piece after with grinding.
4. This intracardiac experiment tissue grinds sampling device is provided with sampling device, can drop when the inside piece of first screen cloth and tissue fluid can drop in the storage shell when using, the inside tissue fluid of storage shell passes through the fretwork hole and discharges, can collect the sample to the tissue piece through the storage shell, the tissue fluid passes behind the second screen cloth simultaneously and falls in arc backup pad top, can get into sampling tube and stock solution ball inside through the feed liquor hole, after the sample finishes, rotate the inner tube, through the feed liquor Kong Dangzhu on the outer sleeve, then take out the sampling tube from the inner tube inside can, the tissue piece of convenient while to solid and the tissue fluid of liquid are collected in the sample collection, and sampling efficiency is higher, also can separate the collection with solid and liquid simultaneously, convenient follow-up use.
Drawings
FIG. 1 is a schematic diagram of an intracardiac experimental tissue grinding and sampling device according to the present invention;
FIG. 2 is a schematic view of a polishing apparatus according to the present invention;
FIG. 3 is a schematic view of a polishing head connection structure according to the present invention;
FIG. 4 is a schematic view of the internal structure of the positioning seat according to the present invention;
FIG. 5 is a schematic view of a stationary base structure according to the present invention;
FIG. 6 is a schematic view showing the internal structure of the fixing base of the present invention;
FIG. 7 is a schematic diagram of a sampling device according to the present invention;
FIG. 8 is a schematic diagram of the internal structure of the sampling device according to the present invention.
In the figure: 1. grinding a base; 2. grinding the bracket; 3. a grinding device; 31. a fixed base; 311. a base body; 312. a first screen; 313. a storage tank; 314. an arc-shaped supporting plate; 315. a second screen; 316. sealing the chute; 317. a sealing plate; 318. an air charging nozzle; 32. grinding the groove; 33. a connecting bracket; 34. a lifting rod; 35. a grinding head; 36. a driving motor; 37. a positioning seat; 38. a positioning groove; 39. adsorbing a magnet; 4. a sampling device; 41. an outer sleeve; 42. an inner cylinder; 43. a sampling tube; 44. a liquid inlet hole; 45. a liquid storage ball; 46. and a storage case.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-4, the present invention provides a technical solution: the device comprises a grinding base 1, wherein the top of the grinding base 1 is fixedly connected with a grinding support 2, the top of the grinding support 2 is fixedly connected with a grinding device 3, and the part, below the grinding device 3, of the top of the grinding base 1 is fixedly connected with a sampling device 4;
the polishing apparatus 3 includes:
the grinding device comprises a fixed base 31, a grinding device and a lifting rod, wherein the fixed base 31 is provided with a circular disc-shaped structure and a grinding groove 32 arranged at the top of the fixed base 31, the top of the fixed base 31 is fixedly connected with a connecting bracket 33, and one side of the connecting bracket 33 is fixedly connected with the lifting rod 34;
the grinding head 35, the grinding head 35 has a spherical structure, and a driving motor 36 arranged above the grinding head 35, the top of the driving motor 36 is fixedly connected with the movable end of the lifting rod 34;
the positioning seat 37, the positioning seat 37 has a circular disc structure, and a positioning groove 38 arranged at the top of the positioning seat 37, the bottom of the inner wall of the positioning groove 38 is fixedly connected with an adsorption magnet 39, the bottom of the positioning seat 37 is fixedly connected with the top of the grinding head 35, and the driving shaft of the driving motor 36 extends into the positioning groove 38 and is in sliding connection with the inner wall of the positioning groove 38.
The bottom of the fixed base 31 is fixedly connected with the top of the grinding support 2, and the shape of the grinding head 35 is matched with the shape of the grinding groove 32.
A magnet block matched with the adsorption magnet 39 is fixedly connected to the driving shaft of the driving motor 36, a limiting sliding groove is formed in the inner wall of the positioning groove 38, and a limiting sliding bar matched with the limiting sliding groove is fixedly connected to the side face of the driving shaft of the driving motor 36.
Be provided with grinder 3, place the biological tissue during the use and grind inslot 32 inside, drive the grinding head 35 of driving motor 36 below through lifter 34 and insert inside grinding groove 32, then drive grinding head 35 through driving motor 36 and rotate and grind the inside tissue of grinding groove 32, when grinding the end and need wash grinding head 35, directly pull out grinding head 35 and positioning seat 37 from driving motor 36's drive shaft can, fix grinding head 35 through the adsorption force between the inside adsorption magnet 39 of constant head tank 38 and the epaxial magnet piece of driving motor 36's drive, pull out the plug-in structure and make easy dismounting, conveniently change and clear up grinding head 35.
Referring to fig. 1-6, the present invention provides a technical solution based on the first embodiment: the fixed base 31 comprises a base body 311, a grinding groove 32 is arranged at the top of the base body 311, a first screen 312 is fixedly connected to the bottom of the inner wall of the grinding groove 32, a storage groove 313 is arranged at the bottom of the base body 311, an arc-shaped supporting plate 314 is fixedly connected to the inner wall of the storage groove 313, a second screen 315 is fixedly connected to the part of the inner wall of the storage groove 313 above the arc-shaped supporting plate 314, a sealing chute 316 is arranged at the top of the base body 311, a sealing plate 317 is slidably connected to the inner wall of the sealing chute 316, an inflating nozzle 318 is penetrated and fixedly connected to the sealing plate 317, the bottom of the base body 311 is fixedly connected with the top of the grinding bracket 2, the top of the base body 311 is fixedly connected with the bottom of the connecting bracket 33, the grinding groove 32 is arranged inside the sealing chute 316, a sealing gasket is arranged between the sealing plate 317 and the sealing chute 316, the mesh diameter of the second screen 315 is smaller than that of the first screen 312, the fixed base 31 is arranged, after the tissues in the grinding groove 32 are ground, small fragments and tissue fluid pass through the first screen 312 and enter the upper part of the second screen 315, the tissue fluid passes through the second screen 315 and enters the upper part of the arc-shaped supporting plate 314, so that the separation of the fragments and the tissue fluid can be completed, the solids and the fluid can be automatically separated after the grinding, the follow-up experiment is convenient, the sealing chute 316 and the sealing plate 317 are simultaneously arranged, after the grinding is finished, the sealing plate 317 can be slid into the sealing chute 316, then the air is filled into the grinding groove 32 through the air filling nozzle 318, the air pressure in the grinding groove 32 is increased, the air pressure above the second screen 315 is increased, the speed of the tissue fluid passing through the screens can be accelerated through the air pressure, the separation speed is improved, and the tissue fluid and the ground fragments can be separated more thoroughly.
Referring to fig. 1-8, the present invention provides a technical solution based on the first embodiment and the second embodiment: sampling device 4 includes outer sleeve 41, outer sleeve 41 inner wall sliding connection has inner tube 42, inner tube 42 inner wall sliding connection has sampling tube 43, outer sleeve 41, inner tube 42 and sampling tube 43 side all have seted up feed liquor hole 44, sampling tube 43 bottom intercommunication has stock solution ball 45, outer sleeve 41 and inner tube 42 are run through at sampling tube 43 top and fixedly connected with storage shell 46, the fretwork hole has been seted up to storage shell 46 side, outer sleeve 41 top runs through arc backup pad 314 and first screen cloth 312 and with arc backup pad 314 and first screen cloth 312 fixed connection, the shape looks adaptation of storage shell 46 and inner tube 42 inner wall, feed liquor hole 44 extends to arc backup pad 314 top, be provided with sampling device 4, can drop inside piece and the tissue fluid of first screen cloth 312 when can drop inside storage shell 46 during the use, can collect the sample through the fretwork hole to the tissue piece, the tissue fluid passes behind the second screen cloth 46 and then drops in arc backup pad 314 top, can get into inner tube 43 and stock solution ball 45 inside through feed liquor hole 44, after the sample end, rotate, can separate the solid sample tube 43 through 42 and can be followed by the sample fluid, and can be conveniently collect the solid sample fluid 315 simultaneously, can be separated with the solid sample hole 315, and can be convenient after the sample the solid is carried out, can be removed simultaneously, and the solid sample is convenient.
It will be apparent that the described embodiments are only some, but not all, embodiments of the invention. All other embodiments, which can be made by those skilled in the art and which are included in the embodiments of the present invention without the inventive step, are intended to be within the scope of the present invention. Structures, devices and methods of operation not specifically described and illustrated herein, unless otherwise indicated and limited, are implemented according to conventional means in the art.
Claims (1)
1. The utility model provides an intracardiac experiment tissue grinds sampling device, includes grinding base (1), its characterized in that: the top of the grinding base (1) is fixedly connected with a grinding support (2), the top of the grinding support (2) is fixedly connected with a grinding device (3), and a sampling device (4) is fixedly connected with the part, below the grinding device (3), of the top of the grinding base (1);
the grinding device (3) comprises:
the grinding device comprises a fixed base (31), wherein the fixed base (31) is provided with a circular disc-shaped structure and a grinding groove (32) arranged at the top of the fixed base (31), the top of the fixed base (31) is fixedly connected with a connecting bracket (33), and one side of the connecting bracket (33) is fixedly connected with a lifting rod (34);
the grinding head (35) is provided with a spherical structure, and a driving motor (36) arranged above the grinding head (35), wherein the top of the driving motor (36) is fixedly connected with the movable end of the lifting rod (34);
the positioning seat (37) is provided with a circular disc-shaped structure and a positioning groove (38) arranged at the top of the positioning seat (37), an adsorption magnet (39) is fixedly connected to the bottom of the inner wall of the positioning groove (38), the bottom of the positioning seat (37) is fixedly connected with the top of the grinding head (35), and a driving shaft of the driving motor (36) extends into the positioning groove (38) and is in sliding connection with the inner wall of the positioning groove (38);
the fixed base (31) comprises a base body (311), the grinding groove (32) is formed in the top of the base body (311), a first screen (312) is fixedly connected to the bottom of the inner wall of the grinding groove (32), a storage groove (313) is formed in the bottom of the base body (311), an arc-shaped supporting plate (314) is fixedly connected to the inner wall of the storage groove (313), a second screen (315) is fixedly connected to the part, above the arc-shaped supporting plate (314), of the inner wall of the storage groove (313), a sealing chute (316) is formed in the top of the base body (311), a sealing plate (317) is connected to the inner wall of the sealing chute (316) in a sliding mode, an inflating nozzle (318) penetrates through the sealing plate (317), the bottom of the base body (311) is fixedly connected with the top of the grinding support (2), the bottom of the base body (311) is fixedly connected with the bottom of the connecting support (33), the grinding groove (32) is formed in the inside the sealing chute (316), a sealing gasket is arranged between the sealing plate (317) and the sealing chute (316), and the diameter of the mesh of the second screen (315) is smaller than that of the first screen (312);
the sampling device (4) comprises an outer sleeve (41), an inner cylinder (42) is slidably connected to the inner wall of the outer sleeve (41), a sampling tube (43) is slidably connected to the inner wall of the inner cylinder (42), liquid inlet holes (44) are formed in the lateral surfaces of the outer sleeve (41), the inner cylinder (42) and the sampling tube (43), liquid storage balls (45) are communicated with the bottom of the sampling tube (43), the top of the sampling tube (43) penetrates through the outer sleeve (41) and the inner cylinder (42) and is fixedly connected with a storage shell (46), and hollowed-out holes are formed in the lateral surface of the storage shell (46);
the bottom of the fixed base (31) is fixedly connected with the top of the grinding bracket (2), and the shape of the grinding head (35) is matched with the shape of the grinding groove (32);
a magnet block matched with the adsorption magnet (39) is fixedly connected to the driving shaft of the driving motor (36), a limiting chute is formed in the inner wall of the positioning groove (38), and a limiting slide bar matched with the limiting chute is fixedly connected to the side surface of the driving shaft of the driving motor (36);
the top of the outer sleeve (41) penetrates through the arc-shaped supporting plate (314) and the first screen (312) and is fixedly connected with the arc-shaped supporting plate (314) and the first screen (312);
the shape of the storage shell (46) is matched with the shape of the inner wall of the inner cylinder (42), and the liquid inlet hole (44) extends to the upper part of the arc-shaped supporting plate (314);
the lifting rod (34) drives the grinding head (35) below the driving motor (36) to be inserted into the grinding groove (32), and the driving motor (36) drives the grinding head (35) to rotate so as to grind the inside of the grinding groove (32).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310077104.1A CN115876513B (en) | 2023-02-08 | 2023-02-08 | Intracardiac experiment tissue grinds sampling device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310077104.1A CN115876513B (en) | 2023-02-08 | 2023-02-08 | Intracardiac experiment tissue grinds sampling device |
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| Publication Number | Publication Date |
|---|---|
| CN115876513A CN115876513A (en) | 2023-03-31 |
| CN115876513B true CN115876513B (en) | 2023-10-27 |
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| CN202310077104.1A Active CN115876513B (en) | 2023-02-08 | 2023-02-08 | Intracardiac experiment tissue grinds sampling device |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN212383758U (en) * | 2020-04-17 | 2021-01-22 | 吉林大学第一医院 | Medicine reducing mechanism is used in emergency nursing |
| CN212844598U (en) * | 2020-08-17 | 2021-03-30 | 西藏自治区农牧科学院畜牧兽医研究所 | Organ tissue deposited worm egg collecting device |
| CN114146799A (en) * | 2021-12-01 | 2022-03-08 | 葛贤杰 | Medical treatment is cosmetic with plant liquid grinding extraction equipment |
| CN217745970U (en) * | 2022-07-26 | 2022-11-08 | 塔里木大学 | Plant extract separating device |
-
2023
- 2023-02-08 CN CN202310077104.1A patent/CN115876513B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN212383758U (en) * | 2020-04-17 | 2021-01-22 | 吉林大学第一医院 | Medicine reducing mechanism is used in emergency nursing |
| CN212844598U (en) * | 2020-08-17 | 2021-03-30 | 西藏自治区农牧科学院畜牧兽医研究所 | Organ tissue deposited worm egg collecting device |
| CN114146799A (en) * | 2021-12-01 | 2022-03-08 | 葛贤杰 | Medical treatment is cosmetic with plant liquid grinding extraction equipment |
| CN217745970U (en) * | 2022-07-26 | 2022-11-08 | 塔里木大学 | Plant extract separating device |
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| CN115876513A (en) | 2023-03-31 |
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