CN115869364A - Central nervous system medicine of targeted sodium ion channel chloride ion channel - Google Patents

Central nervous system medicine of targeted sodium ion channel chloride ion channel Download PDF

Info

Publication number
CN115869364A
CN115869364A CN202111141883.4A CN202111141883A CN115869364A CN 115869364 A CN115869364 A CN 115869364A CN 202111141883 A CN202111141883 A CN 202111141883A CN 115869364 A CN115869364 A CN 115869364A
Authority
CN
China
Prior art keywords
nervous system
formula
concentration
tea
inhibits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202111141883.4A
Other languages
Chinese (zh)
Inventor
许颢瀚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202111141883.4A priority Critical patent/CN115869364A/en
Publication of CN115869364A publication Critical patent/CN115869364A/en
Pending legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a central nervous system drug targeting a sodium ion channel chloride ion channel, the existing central nervous system drug has defects, has large side effects after long-term use, such as neuropathic pain, and no new drug is sold on the market in nearly 20 years due to the complexity of pathogenesis and insufficient understanding of pathogenesis; because the market lacks good neuropathic pain drugs, the U.S. NIH ranks pain research as one of five major neurological research directions; the international pharmaceutical companies such as Asliking, li Lai and Hui Rui invest heavy gold and develop drugs for treating neuropathic pain with Nav1.7 and Nav1.8 as targets, which are not successful at present; the formula of the invention comprises: the highest concentration of sodium chloride (approximately equal to 26.47 percent) in the high-concentration tea components and the solution is similar to the highest concentration of sodium ions and the highest concentration of chloride ions in pharmacy; the formula has the core characteristic of rapid delivery in the nervous system of a human body, and the formula is a targeted sodium ion channel and a chloride ion channel; the formula of the invention can inhibit central nervous system pain, and simultaneously inhibit central nervous system diseases, such as AD, parkinson, epilepsy, nervous system diseases and the like, and inhibit muscular atrophy; the invention is characterized by simultaneously acting on nerves and immunity, being beneficial to improving the life span and the health level of human beings, and belongs to the medical category.

Description

Central nervous system medicine of targeted sodium ion channel chloride ion channel
Technical Field
The invention belongs to the field of medical treatment, and the development and progress of the medicine are rapid, but the development of the central nervous system medicine, especially the medicine for eyes and brain is still slow. Many medical literatures suggest that targeting sodium ion channels and chloride ion channels can become potential treatment methods for pain, tumors, inflammations, nerves, muscles, amino acid absorption drugs and the like, but the difficulties are high, such as neuropathic pain, and no new drugs are available in the market in 20 years due to the complexity and insufficient understanding of the pathogenesis. Because the market lacks good neuropathic pain drugs, the U.S. NIH ranks pain research as one of five major neurological research directions; the international pharmaceutical companies such as Asliking, li Lai and Hui Rui invest heavy gold and develop drugs for treating neuropathic pain with Nav1.7 and Nav1.8 as targets, which are not successful at present;
the inventor deduces that the concentration of ions and micromolecules such as amino acid with specific proportion is quickly increased and is conveyed into a nervous system of a human body, the concentrations of ions and transmitters inside and outside the nerve cell membrane of the human body are close to the concentration of the ions and transmitters of the nerve cell membrane of the octopus squid in a short time, so that the regeneration capacity similar to the octopus squid is generated in the human body, and the deduction is effective through long-time small-range human body experiments; the pain relieving effect has no opioid addiction and drug dependence, and the pain relieving speed is high; the simultaneous combined action of the human nervous system and the immune system is an effective medical treatment mode, the formula acts on the central nervous system, the effect can be fixed in time and fixed in character, organ inflammation storm can be effectively avoided, and the medical treatment method has positive significance.
The invention relates to a central nervous system drug targeting a sodium ion channel chloride ion channel, which can be widely applied to any part of a human body besides the brain and eyes, and belongs to the medical treatment range.
Background
The current anti-aging frontier technologies of modern medicine comprise: nicotinamide mononucleotide product, stem cell technology, gene technology, intermittent eating, replacement of blood of young people into the body of old people, ginsenoside antioxidant and other methods are all used for fighting against the length of life, and the life, the old and the death are natural rules.
The mainstream scientific view of brain diseases such as Alzheimer's disease is that beta-amyloid protein and Tau protein in the brain are entangled, so that a large number of neurons in the brain die, and the memory function is gradually lost, and meanwhile, the problems of inflammation, eye function reduction, diabetes and other senile diseases are accompanied. The application of brain neurons is a difficult problem in the medical field, the aging reasons of neurons are very complex, and breakthrough wounds are searched in the medical preschool subjects of modern genetics, stem cell science and the like.
10 research teams such as the medical college of Australian Kedicken university, published a paper in 9 months 2020, and found that the retina is an extension of the central nervous system and can provide 'strategic observation' of the brain, and the function, structure, metabolism and blood vessels of the retina change in the early stage of AD; the protein deposition observed in the eye is much smaller compared to that of the brain of AD patients, confirming laterally that small amyloid proteins delivered from the brain are present in the eye simultaneously; the resulting damage to the optic nerve; inflammatory proteins in the brain can be slowly transported to the eye;
in 2015, 6/1/Nature journal published a study of the presence of lymphatic vessels in the brain, researchers at the university of Virginia medical school determined that the brain was directly connected to the immune system via some vessels previously thought to be absent, and professor brain immune center for this study was responsible for the interpretation by Dr Jonathan: like all other tissues, the brain can interact with the peripheral immune system through meningeal lymphatic vessels, which subverts the past concept that the brain is an immune-privileged organ. This finding provides important information for explaining the causes of senile dementia, autism, depression, epilepsy, parkinson's disease and multiple sclerosis; for example, senile dementia AD, some inflammatory proteins accumulated in brain, such as beta-amyloid and Tau-entangled protein, can not be effectively eliminated due to blockage or dredging of lymphatic vessels, so that the inflammatory proteins are accumulated in brain.
According to the technology, firstly, eyes actively absorb the formula solution, the nerve route from the eyes to the brain is obtained, the formula solution is absorbed and filtered through cornea, starts from optic nerves to pass through visual cross, visual tract and visual radiation, finally reaches the visual center of occipital lobe, and then is diffused to the brain; the active ingredients in the formula solution can be delivered from eyes into brains in high concentration;
the two key points are that the formula is dripped into the eye and is rapidly absorbed and delivered into the brain by cornea and optic nerve cells, the formula mechanism is sodium ion chloride ion acceleration transmembrane transport interaction and amino acid multi-target effect, tau inflammatory protein and the like in the eye can appear at the position of the eyelid under the eyeball or the position of the eye droppings within 24 hours, and the amount of the Tau inflammatory protein and the like is increased suddenly, and the Tau inflammatory protein and the like are fixed at the beginning of eye dripping; the other point is that mucus appears on the posterior pharyngeal wall and the anterior pharyngeal wall after about 1 minute after the eye drops are dropped, the mucus is a result of the combined action of an immune system and a nervous system and is secreted by lymphatic vessels around the eyes, the phenomenon can not change even in human body experiments after the eye drops are dropped for years, as long as the eye drops are used, the lymphatic vessels around the eyes of the eyes and the meningeal lymphatic vessels can be quickly unobstructed, and metabolic wastes in the brain are transferred out from the meningeal lymphatic vessels instantly, which is a point.
The active absorption from the eye to the brain, the instant input in the form of an electrical signal is a new finding, and the instant output of waste mucus from the brain meninges lymphatic vessels to the eye periocular lymphatic vessels is also a new finding; this was gradually discovered in a cumulative large number of experiments; the nervous system and immune system pathways from the eye to the brain, which have the potential to address the transient export mechanism of inflammatory substances from the brain, are probably potential AD-suppressing methods and probably the most important key point for human beings to resist aging.
The active and automatic absorption by eyes is very similar to the absorption of root systems of plants, and after the eyes absorb the formula solution, the frequency of eye dropping is increased, the eye drop can be transmitted to the brain in an electric signal mode, then to the spine, and then spreads all over the body, so that the process can be called that the nervous system is similar to the properties of plants. The old patient is dropped into the eye for about 40 days, the Parkinson hand tremor lasting for years basically disappears, and the cramps of the legs disappear once a day at night, which is a very ideal result. The formula has common characteristics for treating central nervous system diseases such as aging, alzheimer's disease, depression, parkinson and the like, and the practical application process of the formula is explained below.
Disclosure of Invention
The invention aims to solve the technical problem that the central nervous system medicament targeting the chloride ion channel of the sodium ion channel has the advantages of less side effect, good effect and uncomplicated operation, and has positive significance for improving the healthy life and the living quality of human beings.
A central nervous system drug targeting a sodium ion channel chloride ion channel is characterized by comprising the following components in percentage by weight: combining tea leaf components with sodium chloride; tea components and sodium chloride are slightly different from different tea components, for example, the amino acids of tea are found to be more than 20, and the amino acid types, tea polyphenol content, inorganic matter types and the like of different tea are slightly different; the tea mainly comprises the following components: amino acids (theanine, asparagine, glutamic acid, glycine, serine, tryptophan, valine, histidine, arginine, threonine, alanine, proline, cysteine, tyrosine, methionine, lysine, isoleucine, leucine, phenylalanine, etc.) vitamins (C, B1, B2, B3, B5, B6, B11, B12, P1, H, a, D, E, K, etc.), alkaloids (caffeine, theophylline, theobromine, etc.), tea polyphenols (catechin, flavonoid, anthocyanidins, phenolic acids, etc.), fatty acid lipids (saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, phospholipids, glycerides, sulfatides, glycolipids, etc.), inorganic substances (potassium, phosphorus, calcium, magnesium, iron, sulfur, aluminum, fluorine, etc.); one of the formula solutions is that the salinity of sodium chloride reaches saturation (approximately equal to 26.47 percent) and is combined with the high concentration of the Tieguanyin tea components; the formula is an amino acid supplement and is also a neurotransmitter supplement.
A central nervous system drug targeting a chloride channel of a sodium channel, wherein the formulation, according to claim 1, targets the immune system, inhibits various types of lymphatic vessel blockages of the immune system, inhibits immune diseases, inhibits inflammatory storms; the formula is applied to eyes, so that firstly, inflammatory proteins in the eyes can be led out, secondly, eye drops can repair and dredge periocular lymph of the eyes to cerebral meninges lymph vessels, and mucus (cerebral metabolic waste) is rapidly discharged from pharyngeal walls and nasal cavities before and after a fixed position; the brain can produce interaction with periocular lymphatic vessels of peripheral immune system through meningeal lymphatic vessels to discharge cerebral metabolites, and inhibit brain diseases such as Alzheimer's Disease (AD); the formula is applied to any immune system part of the whole body, has fixed properties, dredges lymphatic vessels, secretes mucus at the fixed part, has large and more mucus secretion amount during inflammation, and has less mucus secretion amount reduced by inflammation.
A cns drug targeting the chloride channel of the sodium ion channel, wherein the rapid association of the formula with the cns, nervous system and immune system is one of the characteristics of the formula applied to the human body according to claim 1, wherein the formula has fixed post-use properties in the eye, rectum, mouth, lung, skin, etc., mucus and fixed secretion site; the formula can inhibit central nervous system diseases and peripheral nervous system diseases.
A cns drug targeting the chloride channel of the sodium channel, wherein the formulation of claim 1, wherein the highest concentration of sodium chloride (≈ 26.47%), one of the prerequisites for safe use of sodium and chloride in humans, is used in combination with a high concentration of tea ingredients; the formula targets a sodium ion channel and a chloride ion channel; targeting sodium ion channels is known to have 9 subunits (Nav1.1-1.9), such as targeting Nav1.7 and Nav1.8 inhibits neuropathic pain; targeting chloride channels is known to have 9 subunits (CLC 0-8), e.g., targeting CLC-3 inhibits tumors and inflammation.
A central nervous system drug targeting a chloride channel of a sodium channel, wherein the formulation has strong hydrophobicity, inhibits the propagation of harmful viruses and inhibits the propagation of harmful bacteria in a human body according to claim 1; the antibacterial mechanism is the transmembrane transport interaction and the amino acid target of high-concentration sodium ions and chloride ions, the antiviral mechanism is strong hydrophobicity and physically damages a virus membrane structure, inhibits the fusion of the virus membrane structure and human cells, the formula effect influences nerve cells and immune cells to quickly start immune enhancement, and inflammatory components of cells are quickly separated and discharged; the formula has the advantages of high efficiency of inhibiting bacteria and viruses, stable effect, high speed and low side effect of inhibiting bacteria and virus mixed inflammation.
A central nervous system agent targeting the chloride channel of the sodium channel, wherein the formulation of claim 1 inhibits pain, inhibits hair loss, inhibits sexual dysfunction, inhibits cancer, inhibits neurodegeneration, inhibits muscle atrophy; one of the core mechanisms is to promote the concentration of sodium ions and chloride ions in the nerve cell membrane of a human body, the concentration of micromolecular neurotransmitters such as various amino acid concentrations and the like to be instantly improved, transfer the high-concentration sodium ions and chloride ions across the membrane, accelerate substance transportation and interaction and simultaneously act on multiple amino acid targets, reach or exceed the concentration of the sodium ions and chloride ions in the nerve cell membrane of regeneration-capable species such as squid octopus and the like, and trigger a repair and regeneration mechanism; the second core mechanism is that the nervous system and the immune system are linked together almost at the same time, and the drug delivery and waste output are completed in a short time; while pain is minimal; the mechanism of the formula for promoting muscle growth is that nerve injury is firstly repaired to promote repair and regeneration of nervous system injury, immunity is enhanced, excretion of metabolic waste is accelerated, and then vascular tissues and muscle tissues in tissues realize gradual growth.
The central nervous system medicine targeting the sodium ion channel chloride ion channel is characterized in that according to the claim 1, in practical application, the formula of the invention is not limited to be used in the brain and the eyes of human beings, and can also be used for treating diseases of tissues at any parts of the human bodies, and can also be used for treating diseases of animals and pets, the formula of the invention can be applied to the whole human bodies in a mode of not being limited to injection, smearing, dripping, atomizing, soaking, sticking and the like, and can be prepared into a finished product mode comprising any pharmaceutically-related production and manufacturing process modes of tablets, injection, atomizing, plasters, sticking, smearing, acupuncture point sticking, atomizing and the like, and any combination thereof.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the following examples further illustrate the present invention in detail, and it should be understood that the specific embodiments described herein are only for explaining the present invention and are not to be construed as limiting the present invention.
For years, research literatures on tea leaves are numerous, and the safety degree of safety toxicological analysis on tea leaf components is high: tea leaves have a history of thousands of years of consumption and can be said to be one of the safest foods for humans; a new herbal prescription approved by FDA in the United states according to the botanical drug guide for the first time, has a trade name of Veregen, is MEDI-geneAG of Germany company, has an indication that genital warts caused by Human Papilloma Virus (HPV) are external skin ointment.
The medicinal components and clinical application value of tea polyphenol are well documented in Chinese and foreign literatures, tea polyphenol is a general name of polyphenol compounds contained in tea, tea polyphenol is a pure natural antioxidant, has excellent antioxidant capacity, is proved by epidemiological investigation, clinical research and in vitro cell culture to have a plurality of benefits in health, and has pharmacological functions of resisting oxidation, inhibiting inflammation, resisting tumor, resisting aging, resisting radiation and the like [1].
In the toxicology aspect of tea polyphenol, isbrucker and the like [2] analyze EGCG toxicity in animal experiments from the aspects of genotoxicity and teratogenic developmental toxicity respectively, and the results show that no genotoxicity effect is seen in body fluid analysis of mice, and no influence on malformation is found in teratogenic and developmental toxicity experiments. The tea polyphenol has high safety.
The tea polyphenol is found in the research of rheumatoid arthritis and osteoarthritis, and can reduce the release of inflammatory factors such as TNF-a, IL-1, IL-6, IL-8 and the like through inhibiting lipid peroxidation, regulating and controlling transcription factor NF-kB, limiting the expression of inducible NO synthetase and the like, thereby playing an anti-inflammatory role. In the aspect of osteoporosis, choi et al [3] reported for the first time in 2003 that tea polyphenol active ingredients can promote the survival of osteoblasts MC3T3-E1 and ALP activity to inhibit the apoptosis of osteoblasts by reducing TNF-alpha and IL-6. Subsequently, takai et al [4] found in MC3T3-E1 osteoblast studies that EGCG reduced IL-6 and IL-6mRNA expression by inhibiting platelet-derived growth factor-BB through the SAPK/JNK pathway. In a recent study, shen et al [5] found that green tea polyphenols may play a role in protecting bone microarchitecture in a study that observes the effects of green tea polyphenols inhibiting inflammatory factors in rats on bone microstructure and strength. Recent studies by Joo et al [6] on the effects of EGCG on bone marrow macrophages have also shown that EGCG may prevent LPS-mediated expression of pro-inflammatory genes by blocking NF-. Kappa.B and MAPK signaling pathways. By
The tea polyphenol can effectively inhibit inflammatory factors such as TNF-a, IL-6 and the like, inhibit the apoptosis of osteoblasts and promote the growth of the osteoblasts. The inhibition of LPS in the process is probably a key link for the tea polyphenol to exert the efficacy.
In the literature, the tea component mouse experiment can inhibit AD and inhibit tumors, but the high-efficiency inhibition drug does not appear in the human body experiment and clinical experiment;
the recent Wuyonglin professor at Tianjin university publishes a paper, uses Chinese tea components as raw materials, extracts natural tea nanodots TNDs, and researches on an antibacterial mechanism of methicillin-resistant staphylococcus aureus and a mechanism aiming at H1N1 influenza virus prove that the combination of TNDs and luteolin and the treatment of the pneumonia by adopting atomization absorption and bacterial and virus mixed type are safe and effective;
zhejiang province disease prevention and control center experiment: the high-concentration tea water has good extracellular killing and intracellular proliferation inhibiting effects on novel coronavirus in-vitro cultured cells;
similarly, if the tea component is directly applied to the human body, various problems, a first tolerance problem, damage to the mucosa of the human body by the alkaline component of the high-concentration tea, difficulty in directly absorbing the tea component by the nervous system of the second human body, and even serious side effects are encountered;
thus, the present inventors found out the tea component and the saturated concentration solution of sodium chloride by atomization, and thereby, they could avoid various problems and basically achieve high efficiency and timeliness of suppressing various diseases.
The researchers of the invention compare the high-concentration tea component (more than 40 mg/ml) atomized lung with the sodium chloride and tea component combined atomized lung in the atomization test in 2013; after the high-concentration tea components are atomized into the lung, the alkalinity of the high-concentration tea has uncomfortable feeling on the lung, the sputum excretion effect is unstable, and the mucus removal effect of the lung is unstable;
the tea component and the saturated concentration of sodium chloride is 26.47%, a large amount of mucus can be spit out in 30 minutes due to the atomization of the lung, the sputum excretion effect is very stable, all testers adopting the method in 2013 till now atomize the lung in 30 minutes, breathe out the mouth and the nose, naturally spit out a large amount of sputum in 30 minutes, the lung feels better in the process, and the patient feels more comfortable without foreign body sensation and pain;
another example is that the tea component is atomized and applied to eyes, because of the alkaline substance of tea leaves, high concentration of tea component atomizes eyes, there is discomfort, brain headache and fever cannot be inhibited, and long time tea component atomization has harm to eyes;
the atomized tea component and 26.47 percent of sodium chloride are combined, eyes are atomized at a short distance of 1 cm, discomfort does not exist, headache is inhibited within 30 minutes, and fever is inhibited for about 12 hours; the safety of atomizing eyes is extremely high, the eyes can continuously atomize for two hours, even for four hours, the tolerance of the eyes is good, and no pain or adverse side effect exists.
The high-concentration tea component cannot be directly dropped into the eye, and the cornea is injured due to too high alkalinity;
the combination of the tea component and the sodium chloride of 26.47 percent is used for years and dozens of times a day in an eye-drop human body experiment, the inventor confirms safety after the eye-drop experiment for three years, the old and the middle-aged people in relatives and friends are eye-dropped, the fixation characters are completely consistent, the brain fever and headache can be inhibited quickly and efficiently, the eye-drop can secrete mucus on the front and back pharyngeal walls in about one minute, the mucus can be secreted in the nose, and various uncomfortable symptoms of the brain can disappear quickly after the eye-drop;
we therefore refer to the combination of tea ingredient and sodium chloride 26.47% in the human experiment as solution X.
One of the preparation formulas is that solution X: selecting 200g of Tieguanyin, cleaning tea leaves with purified water, then putting 50g of Tieguanyin into 1 liter of water for boiling, then fishing out the tea leaves, putting in new tea, fishing out again, removing solid residues after continuously increasing the tea concentration, and finally adding sodium chloride to reach the saturated ion concentration;
the X contains more than 20 high-concentration amino acids, vitamin ABCEDKP and the like, and is similar to most substrates containing phospholipid bilayers, vesicle-mediated substrates and channel protein-mediated substrates by adding ions such as Na +, K +, ca +, mg2+, cl-and the like in a specific ratio;
basic experiment:
the benzopyrene elimination experiment is a basic experiment:
the combustion product benzopyrene is a carcinogen. In a space with the volume of 12 cubic meters, the X solution is atomized to fill the whole space, and the combustion wood and paper air is introduced, wherein in one case, the solution is atomized to be fully distributed in the space, and the combustion gas is put in; in another case, the gas is firstly combusted and mixed in the atomized X solution; after the X atomization and the combustion smoke dust are fully mixed and enter about ten minutes, the pungent smell is greatly reduced, and after twenty to thirty minutes, the combustion products such as benzopyrene and the like are quickly removed. The benzopyrene can be removed quickly by the X solution, and the effect is stable.
The grease dissolution experiment is a basic experiment:
the high-viscosity heavy oil dirt of the kitchen range hood with the same amount is placed in the three transparent containers, the solution X with the highest dissolving concentration, the soap solution and the washing powder solution are poured into the three transparent containers at the same time, within 2 minutes, 70-80% of the heavy oil dirt of the solution X is floated on the liquid surface, only about 5% of trace oil dirt of the soap solution and the washing powder solution is floated on the liquid surface after half an hour, and the speed of decomposing the heavy oil dirt by the solution X is far higher than that of the soap solution and the washing powder.
The capability of decomposing severe oil dirt indicates the speed advantage of removing the viscosity of the oil dirt of the solution X, bacteria and viruses which can be inhibited by soap and washing liquid can be inhibited by the solution X, and theoretically, when the solution X reaches the maximum salinity, the bacteria and the viruses which are harmful to human bodies are difficult to reproduce; the capability of dissolving severe oil dirt of the X solution exceeds that of chemical soap and washing powder, which indicates that the capability of inhibiting virus and bacteria is higher than that of chemicals, so that the X solution only needs to be proved to be safe and reliable in the human body and has huge potential for inhibiting bacteria and viruses; the X solution acts on the nervous system and the immune system simultaneously, so that the elimination of harmful substances in the lung is accelerated, and the inhibition and elimination of infectious substances when bacteria and viruses are infected are accelerated, and the speed advantage of the X solution is obvious.
Basic experiment for decomposing ammonium ions and nitrate ions:
in the polluted water, ammonium ions and nitrate ions exist, sodium chloride is counted, the concentration reaches the range of 20% and 26.47% of saturated concentration, and the detection of the ammonium ions and the nitrate ions reaches the lowest value; it is demonstrated that sodium chloride can achieve high efficiency and rapidity in suppressing ammonium ions and nitrate ions if a saturated concentration is used.
X can quickly separate out various inflammatory products such as phosphoric acid inflammatory protein, uric acid inflammatory protein and the like in a human body, and has high speed and extremely low inflammatory reaction.
Of course, the 26.47% sodium chloride solution can not be dripped into eyes, the high-concentration tea solution can not be dripped into eyes, and the formula solution can be safely used in the central nervous system of a human body, including injection and dripping.
Human body experiment:
in 2013 to 2016, a human lung test is carried out, and a lung atomization experiment is carried out for three consecutive years, so that a regularity result is obtained: the fixed cleaning time of the inflammatory substances in the lung is about 20 minutes, the secretion position and the secretion amount are basically consistent, the secretion amount is large during inflammation, and the secretion amount is reduced after the inflammation disappears; no neurotoxicity and side effects are seen;
and (3) deducing: the time and secretion amount, the regular result of the secretion region and the simultaneous action control of the pulmonary nervous system and the immune system are related;
in 2013 to 2016, according to the lung human body experiment in three years, the lung human body experiment has very high safety and no neurotoxicity, and research personnel further perform the human body experiment on the whole body and continue to observe the relevance of X and a nervous system in the experiment (2016-2021);
the design of the experimental thought is as follows,
rectal and buccal (both ends of digestive tract) experiments in sequence; meanwhile, the whole skin smearing experiment is carried out; scalp soaking experiment;
after the safety and the effect without neurotoxicity are observed through experiments; finally, carrying out atomization eye and eye drop experiments;
human body experiments are integrated, and eye atomization experiments are performed 500+ times; eye drop experiment 500+ times; nasal mucosa experiment 500+, pulmonary experiment 1000+; whole body smear experiment 1000+; oral mucosa gingival test 1000+; rectal mucosa contact experiment 1000+; scalp soaking experiment 500+ times, scalp microinjection experiment 50+ times, pain inhibition experiment 100+ times, split or increase X medicine component experiment 300+ times, and correlation basic experiment 700+ times;
summary of eye experiments
Nebulization eye experiment and eye drop experiment:
eyes were nebulized 3 times a week for 20 minutes a time for four weeks; no discomfort and abnormality are found; clear vision
Nebulized eyes 5 times a week, single 20 minutes, for four weeks, observations: no discomfort and abnormality were found; clear vision
Nebulized eyes 7 times a week, single 20 minutes, for four weeks, observations: no discomfort and abnormality were found; clear vision
Eyes were stopped from fogging for 4 weeks and observed: the vision is similar to that before atomization, and is weakened compared with that after atomization; no drug dependence exists;
nebulized eyes 3 times a week, single 60 minutes, for four consecutive weeks, observations: no discomfort and abnormality were found; the vision is clear;
nebulized eyes 7 times a week, single 60 minutes, for four consecutive weeks, observations: no discomfort and abnormality, clear vision
Eyes stopped nebulization for 8 weeks, visual acuity and prior nebulization were similar, with no drug dependence; the periocular muscles are stronger than before;
the aerosolized secretions flowed out of the nasal cavity and the posterior pharyngeal wall five minutes later; there will be about 4 times of secretion, the secretion quantity is fixed at about 4 ml;
eye drop experiment:
once a day, 0.1 ml was dropped for four consecutive weeks, and observed: the signal sensation is felt, and the signal reaches the hindbrain instantly and then dissipates;
four times a day, 0.4 ml, for four consecutive weeks: and (4) observation: the signal sensation is felt, and the signal reaches the hindbrain instantly and then dissipates;
the eye drop was stopped for four weeks, and observation: the dependence and the abnormality of the medicine are not found, and the comfort of the brain is obviously improved;
the eye drops are applied for ten times a day, about 0.1 ml each time, and are continuously applied for four weeks; the signal sensation is felt, and the signal reaches the hindbrain instantly and then dissipates; the secretion flows out from the nasal cavity and the rear pharyngeal wall once in about one minute, and the mucus amount is fixed to about 0.4 ml;
the eye drop was stopped for four weeks, and observation: no drug dependence or abnormality is found, and mucus gradually flows out from the rear pharyngeal wall in the daytime;
keeping about 0.2 ml of eye drops once a day for long-term observation;
obtaining a regularity result:
the nervous system and the immune system act together, the X reaches a specific human body area such as eyes and is fed, and the specific human body area such as eyes actively absorb the X;
the fixed performance traits included: special fixed nerve lines, input signal sensing intensity, X input time, input modes (one point is jumped and one point is dispersed, and the input modes flow linearly), mucus secretion time, mucus secretion positions and mucus secretion amount;
results-once applied to the eye:
fixed route, eye to brain; input intensity, strong inflammation, and weak health; input time, about 1 second; signal mode, point jump point divergence; mucus pasting time is about 1 minute; mucus location, nasal and anterior and posterior pharyngeal walls; the amount of the viscous liquid is about 0.4 ml;
at the beginning of the eye drop experiment, inflammatory proteins of eyes appear under eyeballs and eyeground feces in about 24 hours; the medicine is delivered into the brain on the route from the eye to the brain of the nervous system, meanwhile, the periocular lymphatic vessels of the eye and the meninges lymphatic vessels of the brain are repaired and dredged, and under the combined action, mucus is discharged from the anterior pharyngeal wall, the posterior pharyngeal wall and the nasal position;
results two were administered to the nose;
fixed route, nasal to trigeminal; input intensity, strong inflammation, and weak health; input time, about 4 seconds; signal mode, flowing line shape, strong signal in inflammation and slight feeling in health; mucus sticking time is about 1 minute; mucus location, nose and throat; the amount of the viscose is about 1 ml; the signal path from the nasal side to the trigeminal nerve of the elderly is damaged or broken, the electric signal is sensed to be tingled from the nasal side to the cheek after the nasal side is dripped, the nasal side is continuously used for dripping, the facial nerve is continuously repaired, and the signal is gradually repaired from the cheek to the trigeminal nerve;
results three were applied to the gingival socket:
fixed course, tooth to alveolar nerve; input intensity, strong inflammation, and weak health; input time, about 4 seconds; signal mode, flowing threadlike during inflammation, and slight stimulation to teeth during health; mucus sticking time is about 1-2 minutes; mucus sites, small starch granules in the mouth; the amount of the viscose is about 1-4 ml;
results four administration to the rectum: defecation and exhaustion are carried out for about 1 minute.
Fixed course, defecation reflex nerve; the input intensity is strong, the inflammation is strong, and the health is strong; input time, about 20 seconds; signal mode, rotating flow; mucus sticking time is about 1 minute; mucus location, rectum; the amount of the viscose is about 4 milliliters;
4 ml of X solution is injected into rectum, and in X used by patient with gastrointestinal inflammation, nerve signal conduction can be transmitted to pelvic cavity, stomach and chest, which shows that the signal transmission after the rectum absorbs X is at a distance which is another long distance signal transmission part besides the eye remote transmission signal. Other experiments such as lung experiments, skin whole body smearing and the like have common rules and fixed properties, such as mucus secretion, action time and the like, the lung and skin area is large, and fixed action points are dispersed, so that the lung-moistening and skin-moistening test strip is suitable for full-coverage formula solution, lung atomization and skin smearing; signal mode, almost non-inductive; mucus is about 20 minutes in lung and more than 30 minutes in skin; the mucus amount is about 4 ml in lung, and the mucus amount is dispersed in skin amount; the continuous lung experiment improves the capability of stabilizing the oxygen in the heart and lung of the human body; the sustained whole body smearing experiment can inhibit muscular atrophy and reduce bone density, and is beneficial to muscle growth and bone density growth.
Summary of the experimental results:
first, the eye actively absorbs the formulation and delivers it to the brain, spine, internal organs; the eyes and eye-to-brain pathways may be the key core for reversal of aging; x can be regulated and controlled by increasing or decreasing the flux of X to the brain, the spine, the viscera and the nervous system of four limbs of the body;
secondly, a special fixed route exists in the nervous system, and an input function and an output function exist at the same time; under the intervention of a formula, slow input and slow output are changed into fast input and fast output;
thirdly, the immune system and the nervous system act together to accelerate the discharge of cerebral metabolic wastes, and X acts on all parts of the human body and has general rules and fixed characters;
and (3) analysis results:
the formula X acts on part of a special main route of a nervous system and simultaneously acts on an immune system route, and has the functions of instant input and possible instant output under the combined action of the special main route and the immune system route and the quick output function; intensity of sensation, strong electrical signal of inflammation (onset of use); after the inflammation disappears and the repair is stable, the electric signal is weak;
mucus secretion, large inflammation (initial use) period, instability; the inflammation disappears, and after the repair is stable, the mucus quantity is fixed; formula X can repair the nervous system and the immune system, and has combined action;
the theory is put forward:
na + channels are important drug targets in the human body. The research and development idea of the X medicine is early, and is inspired by the regeneration capacity of octopuses, the ion concentration inside and outside the nerve cell membrane of the octopuses is four times of that of human beings, and the ion concentration, the concentrations of various neurotransmitters and other small molecules are considered to be simultaneously improved and conveyed to be close to a nervous system; the ion concentration and transmitter concentration inside and outside the human nerve cell membrane are changed in a short time, so that the ion concentration of the human nerve system is close to that of the nerve cell membrane of the nerve system of octopus in a short time; the repairing and regenerating effects are realized;
in order to have fixed data as reference, therefore, a concept of 'comparison regeneration value' is set, and the squid and octopus with regeneration capacity are compared, taking Na + as an example, and simple mathematical analysis is carried out:
the formula I is as follows: comparative regeneration value = (X dissolved ion saturation ÷ average body fluid concentration of human or other species) divided by
{ (concentration inside the cell membrane of human or other species + concentration outside the cell membrane of squid) ÷ 2}
The human comparative regeneration value was 113.11
26.47÷0.9=29.41
(9÷49+150÷440)÷2=0.26
29.41÷0.26=113.11
Also, the comparative regeneration value of the squid is calculated to be 5.4,
26.47÷4.9=5.4
(49÷49+440÷440)÷2=1;5.4÷1=5.4;
a cat regeneration value of 55.14 was also obtained
26.47÷1.5=17.65;(15÷49+150÷440)÷2=0.32
17.82÷0.32=55.14
Comparing the regeneration value, 5.4 is a regeneration area, and the farther the distance is from 5.4, the greater the difficulty in realizing regeneration is; dividing the regeneration capacity of the squid octopus by 5.4 to obtain a regeneration difficulty value or a neuron capacity difference value; the regeneration difficulty value can be regarded as the representation of the neuron capability difference;
the formula II is as follows: regeneration difficulty value = comparative regeneration value ÷ 5.45 (squid regeneration value)
Octopus 1
The cat is 10.21
Human 20.94
Using this formula, a simple inference can be drawn: the larger the number of animals, the greater the difficulty of regeneration that needs to be broken through, and the relatively poor physiological flexibility of the part of the locomotion.
We can illustrate that from 20.96 to 1 is a circle; if the process using X is continuous, an adjustable process occurs, a process where the helix approaches 1; this process is a dynamically adjustable process: the adjustable meaning is: the application range is wider, different targets can be set, and the absorption amount and the absorption concentration of X in a human body can be adjusted; such as muscle ability, agility ability; such as healthy ability, long life ability, even learning ability, concentration ability; the improvement of the capability is a spiral approaching process, so the method is very safe, and the inherent property of the species is still kept; for example, the conclusion of a small-range human body experiment is that the eyes actively and automatically absorb X-ray eye feeding once a day, so that the concentration degree can be obviously improved, and the sleep quality can be improved.
This active absorptive capacity of the human nervous system, closely resembles the attributes of plants;
for one of our examples, the difference between the ion concentration of X, na +26.74%, and 0.9% in normal human fluid is 29.71 times; the Na + concentration inside and outside the nerve cell membrane of the squid and the octopus with regeneration capacity is about four times of that of the human; the concentration of ions inside and outside a nerve cell membrane, which is the same as that of octopus squid, can never be reached by human beings, but the concentration of ions and micromolecules in an X set can possibly excite the one-time regeneration capability of the human beings as long as the instantaneous peak value is close to the octopus value;
1, X acts on a human body to act together with a nervous system and an immune system, and in the process of delivering a substrate, a rapid input and output function exists, and aging diseases are accelerated due to weakened output function caused by inflammation and the like;
2, X in the course of medical treatment, the current choice of nervous system repair is ranked first, while the immune system is closely ranked second; subsequently affecting other tissues such as the vascular system and musculoskeletal viscera;
the process of helical approach, X, can be modulated by varying the electrical signal, for example: the strength of gum muscles and teeth, the inventor takes the X solution for 2 minutes in the morning and at night every day, and then gargles and brushes teeth; the teeth are kept in the texture of 20 years old, and the gingival muscles are kept not to be degenerated;
the research and development people are 47 years old, if the X solution is not used, the top of the gingival muscle is whitened in a small range after one month, the gingival muscle is degenerated due to inflammation increase, teeth are loosened, and the teeth become sensitive again due to cold and heat; gingival muscle and tooth health conform to formula inference;
the orbicularis oculi muscles of the eyes also conform to the deduction of a formula;
the eye drops are dropped into the lower eye skin every day for about 20 days, and the orbicularis oculi muscle at the lower part of the eye can be observed to grow gradually;
the eye drops are applied to the inner side and the outer side of the skin every day for about 40 days, the temporalis muscles can be gradually increased, and the temple position slowly swells, so that the eyes of the old people deeply sunk into the orbit gradually rise from the orbit through the muscle action, and the continuous deep sinking of the orbit is inhibited.
The growth of the orbicularis oculi muscle and the temporal muscle also conforms to the formula inference;
human experiments in eye drops;
the medicine is dropped into the eyes twice a day in the morning and at night for 40 consecutive days, and the leg suction is completely disappeared for the old for years and once in the middle of the night; the parkinsonism on the hands disappeared, and also disappeared substantially after 40 days of eye-dropping.
Cramps and parkinson treatment cases also conform to the formula inference;
after 8 years of human experiments, the formula has potential to become a central nervous system drug along with the deepening of the experiments.
For example, by referring to the reason of long life of Greenland sharks, the Na + plasma and the comprehensive transmitter concentration can be comprehensively improved, the absorption amount can be adjusted, and the service life can be prolonged; the muscle mass can be adjusted through the regulation and control effect of the nervous system; the process of regeneration capacity can adjust fat running and accurately regenerate muscles and blood vessels; through the route of the oculocerebral cardiac nervous system, the repair of the systemic nervous system can be realized;
regeneration experiments: one infection is caused on the lower leg part of a patient, the infection time is two months, the wound is wound, the length is about 3 cm, the width is 1.5 cm, the depth is about 0.8 cm, the key is that the infection causes muscle loss, a hole is formed, and the bottom layer of the hole is completely purulent; adhere to tendons, and cannot be tolerated by the pain of pus discharge; the X debridement and soaking can randomly soak the wound because the X has the advantage of low pain, so that debridement patients and doctors are easy; the pus is broken down into small powder samples by changing the soaking liquid 10 times, and it can be seen here how strong the ability of breaking down the garbage is inside the body, because the pus is connected with the muscles and tendons, and there is no damage only by soaking.
Scabbing, which can be seen 6-10 hours after soaking, and has an edge shell which plays a supporting role;
liquid is secreted regularly every day, the lower part of the edge supporting shell is raised continuously, scabs are raised continuously and slowly, and the process is carried out every day;
in the fourth week, determine what is just under the blood crust uncovered?
Adipose stem cells and growth fluid are seen; half of the muscles and blood vessels have grown out;
after 8 weeks, this hole was repaired accurately, and muscle skin and octopus were regenerated, approximately;
the advantages are that:
first debridement without pain; and cleaning; the patient has high comfort level in the whole process;
the second process reduces the pain of the patient; only need to be applied beside the wound;
third, shape recovery is not problematic, avoiding and reducing scar nodules.
When the eye drops are used in eyes, the use of X can obviously improve eye inflammation and improve eyelid muscle strength; the X repair ability is mainly realized by means of the nervous system of the human body,
the first is not painful, certainly nervous system management, generally debridement, ranging from a minor pain to a minor tingling, and then little sensation.
Secondly, strange scabs at the edges of scars support a circle and cover a floor like a foundation, which is the first time in more than forty years, sugar-colored liquid can flow out every day and quickly turns into brown scabs, the liquid flows out at the side, a point is left at the side, the bottom scabs are kept basically still, the scabs are gradually thickened and heightened at the upper side, namely, nerve tissues are covered by an intelligence quotient, the blood scabs are heightened layer by layer, and neurons use the intelligence quotient, which is really interesting. In the human regeneration experiment, the time for repairing the muscles and the nervous system is 8 weeks, which is about two months, and the time is basically consistent with the regeneration time of the animals with the regeneration capability of the nature.
Starvation test:
the human body has no food in the wild, and symptoms such as dizziness, heart discomfort and the like can appear in 24 hours; according to the formula research and development personnel, a hunger experiment is performed for 3-5 days for many times, the hunger experiment is performed for 4-7 times every day, only water is drunk, no food exists in 3-5 days, the hunger dizziness symptom before eye dropping is greatly reduced, the physical strength is still normal after eye dropping, and swimming, hiking and running exercises can be performed normally; is very suitable for field treatment.
Scald experiment: sunburn test:
after being soaked in the X solution after being scalded, the severe pain is rapidly reduced, and the pain basically disappears after 20 minutes; the whole body is sunburned, the X solution is smeared, the inflammation disappears quickly, and the sunburn is not easy to occur after the X solution is smeared;
mosquito bite experiment: the pain is quickly relieved, and the itching is quickly relieved;
injection experiment: the researchers respectively inject 0.1 ml of the solution under the skin at different parts of the body, such as scalp, lymph, belly and toes, the swelling of a small water drop can be seen visually, the solution disappears after about 24 hours, and no other inflammatory reaction is seen;
the old people fall down to hurt the spine and the lumbar, the huge pain cannot move, and the pain is greatly reduced when the old people are injected with 0.1 ml of the formula under the skin; the pain inhibition effect lasts for 10-24 hours, and the lumbar pain of the old is effectively inhibited by injecting 0.1 ml once every two days in the whole rehabilitation period.
In the experiments, the solution formula human body experiment is continuous for 8 years, small-range human body experiments are carried out, eyes are not damaged, lungs and other tissues and organs are not damaged, on the contrary, the eyes, the lungs and the like are helped to be healthy, the experiment process is not complicated to copy, and the operation can be carried out under any laboratory conditions or clinical experiments, so that the effect similar to that of the invention is achieved.
In specific use, the invention provides a central nervous system drug targeting a sodium ion channel chloride ion channel, and the central nervous system drug targeting the sodium ion channel chloride ion channel comprises the following components in parts by weight: combining tea leaf components with sodium chloride; tea components and sodium chloride are slightly different from different tea components, for example, the amino acids of tea are found to be more than 20, and the amino acid types, tea polyphenol content, inorganic matter types and the like of different tea are slightly different; the tea mainly comprises the following components: amino acids (theanine, asparagine, glutamic acid, glycine, serine, tryptophan, valine, histidine, arginine, threonine, alanine, proline, cysteine, tyrosine, methionine, lysine, isoleucine, leucine, phenylalanine, etc.), vitamins (C, B1, B2, B3, B5, B6, B11, B12, P1, H, a, D, E, K, etc.), alkaloids (caffeine, theophylline, theobromine, etc.), tea polyphenols (catechin, flavonoids, anthocyanidins, phenolic acids, etc.), fatty acid lipids (saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, phospholipids, glycerides, sulfatides, glycolipids, etc.), inorganic substances (potassium, phosphorus, calcium, magnesium, iron, sulfur, aluminum, fluorine, etc.); one of the formula solutions is that the salinity of sodium chloride reaches saturation (approximately equal to 26.47 percent) and is combined with the high concentration of the Tieguanyin tea components; the formula is an amino acid supplement drug and is also a neurotransmitter supplement drug.
The peptide is a compound formed by connecting alpha-amino acids together by peptide bonds, has high biological activity, relates to various fields of hormone, nerve, cell growth and reproduction of human bodies, controls the growth, development, immunoregulation and metabolism of the human bodies, plays a role in biological regulation of various metabolic activities and influences the growth, division, differentiation and migration of various cells; the active peptide has different age stages, wherein the secretion is sufficient before the age of 25 years, and the secretion is deficient after the age of 50 years;
in recent years, israel scientists claim that cancer is cured 100% of mice by using polypeptide, the human body needs more than 20 amino acids, and almost countless arrangement modes exist, and one of important options for scientists to develop medicines is to select the polypeptide with medicinal effect;
the formula of the invention is a method for directly feeding more than 20 amino acids to the required parts of human body and then generating active peptide and polypeptide by the amino acids according to the self-demand of human body; the absorption process can be simplified to feeding and active absorption by eyes, so that the eyes are safety barriers, and the absorption process is also a filtering process, so that amino acid, vitamin, ions and the like in the formula required by the eyes are instantly conveyed into the eye nerves and then to the brain;
the formula of the invention is also a regeneration means formula, inspired by regeneration animals such as octopus and squid, the concentration of Na + inside and outside the nerve cell membrane of the octopus and squid is about four times of the concentration of Na + inside and outside the nerve cell membrane of a human body (inside 5 and outside 3), the inventor deduces that the concentration of small molecules such as ion concentration and amino acid with a specific proportion is rapidly increased and is conveyed into the nervous system of the human body, and the concentration of ions inside and outside the nerve cell membrane of the human body and the concentration of transmitter and the like are close to the concentration of the nerve cell membrane ions and the concentration of transmitter and the like of the octopus and squid in a period of time, so that the regeneration capability similar to the octopus and squid is generated in the human body; 26.47% sodium chloride +20 various amino acids = regeneration capacity of the nervous system = highly potent and safe active peptides and polypeptides;
the formula of the invention is also a rapid neurotransmitter supplement process;
because the human body actively absorbs the medicine, the quantity and the times can be satisfied at any time; therefore, the compound has potential for inhibiting aging and treating diseases such as AD and cancer. In recent years, news for searching for polypeptides by AI is not beyond the ear, but is difficult, the arrangement modes of more than 20 amino acids are difficult to count, over the years, the scientific community expends huge cost on amino acid combination medicines, two years of experiments are carried out in nearly hundred plants, and finally tea leaves are selected because of the minimum side effects and neurotoxicity, so that the treatment effect is optimal; the amino acid composition and proportion in the tea are added with sodium chloride, which is just the amino acid composition according with the human body.
In a specific use, the invention provides a central nervous system drug targeting a chloride ion channel of a sodium ion channel, according to claim 1, wherein the formulation targets the immune system, inhibits various lymphatic vessel blockages of the immune system, inhibits immune diseases, inhibits inflammatory storms; the formula is applied to eyes, so that inflammatory proteins in the eyes can be led out, eye drops can repair and dredge lymph around eyes to meninges and lymph vessels of brains, and mucus (brain metabolic waste) is quickly discharged from pharyngeal walls and nasal cavities before and after a fixed position; the brain can discharge cerebral metabolites through the interaction between meningeal lymphatic vessels and peripheral immune system periocular lymphatic vessels, and can inhibit brain diseases such as Alzheimer's Disease (AD); the formula is applied to any immune system part of the whole body, has fixed properties, dredges lymphatic vessels, secretes mucus at the fixed part, has large and more mucus secretion amount during inflammation, and has less mucus secretion amount reduced by inflammation.
In 2015, 6 months 1, nature journal published a study result of the presence of lymphatic vessels in the brain, researchers at the medical college of virginia university determined that the brain was directly connected to the immune system through some vessels previously thought to be absent, and professor brain immune center studied this project was interpreted by Jonathan doctor: like all other tissues, the brain can interact with the peripheral immune system through meningeal lymphatic vessels, which subverts the past concept that the brain is an immune-privileged organ. This finding provides important information for explaining the causes of senile dementia, autism, depression, epilepsy, parkinson's disease and multiple sclerosis formation; for example, senile dementia AD, some inflammatory proteins accumulated in brain, such as beta-amyloid and Tau-entanglement proteins, are not effectively eliminated possibly due to blockage or obstruction of lymphatic vessels, so that the proteins are accumulated in brain.
10 research teams such as the medical college of Australian Kedicken university, published a paper in 9 months 2020, and found that the retina is an extension of the central nervous system and can provide 'strategic observation' of the brain, and the function, structure, metabolism and blood vessels of the retina change in the early stage of AD; the protein deposition observed in the eye was much smaller compared to that of the brain of AD patients, confirming laterally that small amyloid proteins transported out of the brain are present in the eye simultaneously; the resulting damage to the optic nerve;
the formula is applied to the eye drop, and has two key points, namely, the formula is applied to the eye drop, most of inflammatory proteins of the eye can appear at the position of the eyeball eyelid within 24 hours, or the quantity of the eye feces is increased suddenly, and the condition is a fixed character appearing at the beginning of eye drop; the other point is that mucus appears on the posterior pharyngeal wall and the anterior pharyngeal wall after about 1 minute after eye dropping, the phenomenon can not be changed after years, as long as the eye dropping is used, lymphatic vessels around eyes and meninges lymphatic vessels of eyes can be rapidly unobstructed, and metabolic wastes of the brain can be transferred from the meninges lymphatic vessels instantly, which is a key point. Through human body experiments involving in person, the research personnel of the invention discover the following in the formula eye drop experiments: after the eye drops are dropped, the meningeal lymphatic vessels and the peripheral immune system pipeline can be quickly dredged, and inflammatory proteins of the meningeal lymphatic vessels can be quickly discharged from the anterior pharyngeal wall and the posterior pharyngeal wall along with mucus; meanwhile, after the eye drops are dropped, inflammatory protein in the eyes can be quickly separated out from the eyes and stays in the eye sockets; the eye drop with the formula can dredge and repair meninges and lymphatic vessels and remove metabolites of the brain in time by separating out endophthalmitis protein and separating out meninges and lymphatic vessels from periocular lymphatics after dredging, thereby providing a new method for treating AD and other brain diseases.
The immune system consists of immune organs, immune tissues, immune cells and molecules, which cooperate to kill harmful viruses and bacteria, remove toxins and kill tumor cells; in the face of a new coronavirus disaster, it has been determined that a large number of patients have nervous system complications, such as brain diseases, stroke, epilepsy, etc., and the studies have found that more than three patients (36.4%) have nervous system symptoms, which are classified into three categories: central nervous system symptoms (dizziness, headache, disturbance of consciousness, acute cerebrovascular disease, ataxia, seizure); peripheral nervous system symptoms (taste impairment, olfactory impairment, visual impairment, and neuropathic pain); skeletal muscle injury; research shows that part of severe patients have direct invasion of new coronavirus into central nervous system, resulting in systemic inflammatory reaction; at present, all new crown medicaments are directly absorbed by eyes and enter the medicaments for inhibiting fever and headache of the brain, and the formula solution belongs to a few medicaments which can realize the function; the immune storm factor, the immune system destroys human tissues and kills human body, so to speak, the immune storm factor is caused by the double actions of the control failure of the nervous system and the out-of-control of the immune system.
After the lung is atomized, the solution in the formula can basically and completely discharge sputum and mucus blockages in the lung out of the body under the dual action of the neural network of the lung and the immune system of the lung within 30 minutes, and the experiment is accumulated for more than five thousand times of human body experiments from 2013 to the present, and the research and development people and family friends discharge the sputum and the mucus within 30 minutes without exception; also, by eye dropping and atomizing the eye, a large amount of mucus is expelled from the anterior and posterior pharyngeal walls, and headache and fever are rapidly suppressed, where the rapid suppression is not away from the maximum concentration of the formulation of 26.47%, targeting sodium and chloride channels, accelerating transmembrane interactions, promoting the formulation to deliver drugs at the fastest rate in the neural network, producing the fastest response in the immune system, 26.47% of the medical power, thus resulting in stable time and fixed therapeutic outcome profiles.
Researchers inject 0.2 ml of the formula solution into the neck lymph node lump, and the lymph node lump is quickly dissipated; the researchers inject 0.1 ml of solution into the skin of the patient with lumbar disc herniation, and the lumbar disc herniation pain inhibition effect is rapid; the formulation acts at approximately the same time in both the nervous system and the immune system.
The immune system diseases are various, such as arthritis diseases, rheumatoid arthritis and ankylosing spondylitis; immune disorder diseases such as allergic diseases including allergic asthma and allergic rhinitis, systemic lupus erythematosus, vasculitis, and scleroderma; the disease can be inhibited by smearing, injection, dripping atomization and the like; the formula can inhibit immune diseases through three aspects, namely dredging lymphatic vessels to discharge garbage and inflammatory wastes; secondly, inhibiting the reproduction of virus and bacteria and accelerating the discharge of inflammatory products; the third is that the formula accelerates the repair of the nervous system by delivering in the nervous system, and simultaneously leads the nervous system and the immune system to act together to inhibit the diseases of the immune system.
In a specific use, the invention provides a central nervous system drug targeting a sodium ion channel chloride ion channel, according to the claim 1, wherein the formula, targeting the central nervous system of a human body, and the quick linkage of the nervous system and the immune system are one of the characteristics of the formula applied to the human body, and the formula is applied to eyes, rectum, oral cavity, lung, skin and the like, and has fixed post-use properties, mucus and fixed secretion positions; the formula can inhibit central nervous system diseases and peripheral nervous system diseases.
For a long time, the medical administration route is mainly oral medicine and blood injection internal circulation system or intramuscular injection; the administration route of the formulation in the human body is mainly automatically absorbed by the nervous system, metabolic waste is almost simultaneously output through lymphatic vessels of the immune system, the formulation is delivered in the nervous system in a way similar to an electric signal, and after a short time, the immune system associated with the nervous system delivers inflammatory substances out of the human body; because the concentration of the 26.47% sodium chloride is involved, the compound has more stable fixed characters when acting on a human body, such as serious inflammation, strong signal feeling and large secretion of inflammatory substances, the formula treatment reduces inflammation, the signal feeling is weakened or not felt, and the secretion of the inflammatory substances is less; the formula solution is applied to eyes, rectum, tooth sockets, lungs, skin and the like and acts on a human body, general rules and fixed properties exist, and the fixed properties are shown in a human body experiment part; applying to eyes, the formula can rapidly discharge brain inflammation substances through a lymphatic system near the eyes and meninges lymphatic vessels at the back of the brain, the fixed position is the front and back upper pharynx parts, the formula can rapidly lead out inflammatory protein micromolecules at the eyes through the eyes, and the fixed position is the eyeground; the ability of human neurons to absorb the formulation solution has plant-like properties, the eye absorption process is like the rhizome absorption of plants, the eye dropping frequency is increased, and the formulation can be delivered to all parts of the body, from eyes to brain, to spine, to limbs to internal organs; applied to the nasal side, rapidly reaching the trigeminal nerve and cochlea along the neural network; the medicine can be quickly absorbed by nervous system when applied to oral cavity, lung, skin and scalp; the electric signals are sensed to reach the stomach, the chest and the neck from the intestinal tract through the electric signals after the formula solution is absorbed by the rectum, and the electric signals of another sensing line are sensed to reach the hindbrain from the rectum in the experiment of patients with severe gastrointestinal inflammation; the injection is injected near nervous system, and the nervous system can be automatically absorbed to inhibit pain and inflammation.
In a specific use, the invention provides a central nervous system drug targeting a sodium ion channel chloride ion channel, according to claim 1, wherein the formulation, the highest concentration of sodium chloride (≈ 26.47%), one of the preconditions for safe use of the highest concentration of sodium ions and chloride ions in human body, is mixed with a high concentration of tea components for use; the formula targets a sodium ion channel and a chloride ion channel; targeting sodium ion channels is known to have 9 subunits (Nav1.1-1.9), such as targeting Nav1.7 and Nav1.8 inhibits neuropathic pain; targeting chloride channels is known for 9 subunits (CLC 0-8), as is known to inhibit tumor and inflammation by CLC-3.
The reason why the formula targets the selection of sodium ion channels and chloride ion channels is due to many serious disease medical cases, the time is life, and fixed results in time are needed; for example, in the case of coronavirus death, central nervous system inflammation storm is caused, for example, the lung is cleaned for 30 minutes at regular time, the brain pain is inhibited for 30 minutes, the brain fever is inhibited for 12 hours, and for example, the rectum is formulated for 1 minute to start defecation and ventilate; this makes it possible to: the excrement is quickly removed, the cardio-pulmonary oxygen capacity is maintained, and the central nervous system is protected; after serious organ, blood vessel and muscle damage, the pain is small, the repairing and regenerating time is about 8 weeks and two months, and the medical treatment is uniformly implemented, so that more patients can be saved;
who is more important is tea ingredient and chloride ion sodium ion? The high-concentration tea components comprise various amino acids, vitamins, alkaloids and other components, a main target point can be a plurality of amino acid channels, but the tea components cannot be fixed for time and fixed characters when used for medical treatment, but 26.47% of sodium ions and chloride ions in a sodium chloride solution are the highest values, which are stable parameters, and under the influence of the fixed parameters, the treatment time and the treatment effect have the opportunity to realize fixed results and fixed time; researchers tested hundreds of plant combinations seven years ago, and found that the combination can be matched with a sodium chloride solution by 26.47 percent and is safely used in eyes and the central nervous system, and finally only the combination of the formula sodium chloride and the tea ingredients can be determined to safely enter the brain from the eyes.
The formula targets a sodium ion channel and a chloride ion channel, the concentration is 26.47 percent at most, and the premise is that tea components are combined together; the higher the concentration of the tea ingredients is, the higher the use efficiency and safety of the formula solution in a human body are; for example, 200g of Tieguanyin tea is divided into three parts, the three parts are sequentially boiled in 1.5L of water, fished out and put into the water to be boiled and fished out, the concentration of tea ingredients in the solution is gradually increased, the concentration of the solution is more than 40mg/ml, residues in the solution are cleaned out, the residues are poured into a glass bottle to be mixed with sodium chloride, and the concentration of the sodium chloride in the solution reaches the highest dissolving concentration and is approximately equal to 26.47; at the moment, the concentration of sodium ions and chloride ions reaches the maximum value, the formula solution acts on a human body to target a sodium ion channel and a chloride ion channel, the action mechanism is high-concentration sodium ion and chloride ion transmembrane transport, substance transport and interaction are accelerated, and amino acid multi-target points act simultaneously, so that the highest transmembrane transport efficiency is achieved.
However, if the tea ingredient is not contained, only the sodium chloride solution is contained, and if the concentration of sodium ion chloride ions in the sodium chloride solution exceeds 9 percent, the sodium chloride solution is injected into a human body and only acts on sodium ion channels and chloride ion channels of human body cells, a large amount of cell outer membranes are torn, and medical risks and even death are caused; the high-concentration tea solution and the sodium chloride 26.47% are combined together, and in the human body experiment process from 2013 to 2021, the human body safety of the formula in small ranges such as atomization, injection, eye drop, whole body smearing and the like is gradually verified in the human body experiment step by step through one-step experiments, and the formula has higher safety and human body affinity, and particularly has extremely high affinity with the central nervous system of the human body.
The chloride ion channel is mainly characterized by cell swelling dependence, signal molecule coupling, related ion dependence, intracellular protein kinase phosphorylation dependence, ATP hydrolysis reaction coupling and other characteristics. Targeting chloride channels medically can solve a number of problems: such as inhibition of nervous system diseases, inhibition of cardiac arrhythmias, such as inhibition of low uptake of partial amino acids, inhibition of muscle diseases, and the like;
sodium ion channels are classified into sensitive (NAV 1.1, NAV1.2, NAV1.3, NAV1.4, NAV1.6, NAV 1.7) and insensitive (NAV 1.5, NAV1.8, NAV 1.9); the prior literature records that sodium ion channels and prostate cancer, breast cancer, lung cancer, cervical cancer, colon cancer, mesothelioma, neuroblastoma, brain cancer, melanoma, ovarian cancer, lymph cancer and the like have expressions, and voltage-gated sodium ion channels thereof are respectively documented for explanation;
neuropathic pain, due to the complex pathogenesis and insufficient understanding of the disease, has no new medicine on the market in nearly 20 years. Because the market lacks good neuropathic pain drugs, the U.S. NIH ranks pain research as one of five major neurological research directions; the international pharmaceutical companies such as Asliking, li Lai and Hui Rui invest heavy gold and develop drugs for treating neuropathic pain with Nav1.7 and Nav1.8 as targets, which are not successful at present;
scientists have recognized in the literature that targeting sodium and chloride channels would be potential therapeutic approaches for pain, tumors, inflammation, nerve, muscle, amino acid absorption drugs, and the like, but have various difficulties; the formula solution can be said to be a medicine suitable for targeting a sodium ion channel and a chloride ion channel, the formula is safely used in a human body by combining tea components and the highest concentration of sodium ions and the highest concentration of chloride ions, and the formula can effectively inhibit pain, inflammation, tumor, central nervous system diseases and the like.
In a specific use of the present invention, there is provided a central nervous system drug targeting a chloride channel of a sodium ion channel, according to claim 1, wherein the formulation has strong hydrophobicity, inhibits propagation of harmful virus, inhibits propagation of harmful bacteria in a human body; the antibacterial mechanism is the transmembrane transport interaction and the amino acid target of high-concentration sodium ions and chloride ions, the antiviral mechanism is strong hydrophobicity and physically damages a virus membrane structure, inhibits the fusion of the virus membrane structure and human cells, the formula effect influences nerve cells and immune cells to quickly start immune enhancement, and inflammatory components of cells are quickly separated and discharged; the formula has the advantages of high efficiency of inhibiting bacteria and viruses, stable effect, high speed and low side effect of inhibiting mixed inflammation of bacteria and viruses.
If Vibrio vulnificus cannot propagate in 8% concentration salt solution, it can rapidly die under the combined action of 26.47% concentration sodium chloride salt solution and tea component, such as herpesvirus and HIV, and can rapidly inactivate under the combined action of 26.47% concentration sodium chloride salt solution and tea component.
In case-specific use, the above-mentioned cases such as the tea extract for inhibiting bacterial viral pneumonia and the high concentration tea component for inhibiting coronavirus and HIV;
the intestinal micro-ecological disorder of severe patients with the novel coronavirus pneumonia easily causes secondary infection, and finally, the patients die not from the viral infection but from the secondary bacterial infection. It is therefore desirable to eradicate bacteria and viruses without causing excessive inflammation to cause tissue damage; especially for damage to the central nervous system of the brain.
The formula can be applied to eyes in human body experiments, and can dredge from periocular lymphatic vessels of eyes and meningeal lymphatic vessels of brain by simultaneously acting on a nervous system and an immune system, quickly lead cerebral metabolic waste in the meningeal lymphatic vessels, inhibit brain diseases and simultaneously eliminate brain metabolic inflammation protein; meanwhile, the eyes absorb ions and amino acids to enter the brains, pain is inhibited, various amino acids are delivered to the brains, and the polypeptides are formed, so that cerebral neuron autonomous repair brain diseases are facilitated.
The action mechanism of the formula components for inhibiting bacteria is as follows: the target sodium ion chloride ion channel accelerates transmembrane transport interaction and acts with various amino acid targets at the same time: the mechanism of virus inhibition is: the formula accelerates adsorption on the surface of virus, the hydrophobicity and the strong lipophilic group inhibit the activity of virus, the virus envelope is broken and damaged, the virus envelope is adsorbed on human cells, transmembrane transport is accelerated, and inflammatory substances and virus fragments are eliminated. According to human body experiments, the formula can inhibit virus and bacteria, and is effective in different tissues and organs of human body.
Many medical documents describe viruses such as ebola virus, herpes virus, and aids virus in the human body that can remain latent or dormant for a long period of time deep in the body where the immune response is weak, such as eyes, joints, brain, etc., and studies have shown that viruses persist in body fluids (semen, milk) that infect survivors. So-called disease cure is only a relative concept, and the actual disease progression is extremely complex; there is still a risk of viral or bacterial infection with the burning ash, and there is a need to find an antiviral drug that destroys or at least renders the hidden virus harmless; there are now many cases of coronaviruses that are also increasingly similar. The formula solution belongs to an antiviral drug which can make virus and bacteria harmless, and can inhibit the mass propagation of microorganisms hidden in a human body and realize the harmlessness of the human body by jointly combining smearing, intestinal tract dredging, lymph dredging and eye drop supplementing neurotransmitter to repair a nervous system.
In a particular use of the invention, there is provided a central nervous system drug targeting the chloride channel of the sodium ion channel, according to claim 1, wherein the formulation inhibits pain, inhibits hair loss, inhibits sexual dysfunction, inhibits cancer, inhibits neuronal atrophy, inhibits muscle atrophy; one of the core mechanisms is to promote the concentration of sodium ions and chloride ions in the nerve cell membrane of a human body, the concentration of micromolecular neurotransmitters such as various amino acid concentrations and the like to be instantly improved, transfer the high-concentration sodium ions and chloride ions across the membrane, accelerate substance transportation and interaction and simultaneously act on multiple amino acid targets, reach or exceed the concentration of the sodium ions and chloride ions in the nerve cell membrane of regeneration-capable species such as squid octopus and the like, and trigger a repair and regeneration mechanism; the second core mechanism is that the nervous system and the immune system are linked together almost at the same time, and drug delivery and waste output are completed in a short time; while pain is minimal; the mechanism of the formula for promoting muscle growth is that nerve injury is firstly repaired to promote repair and regeneration of nervous system injury, immunity is enhanced, excretion of metabolic waste is accelerated, and then vascular tissues and muscle tissues in tissues realize gradual growth.
Neuropathic pain, due to the complex pathogenesis and insufficient understanding of the disease, has no new medicine on the market in nearly 20 years. Because the market lacks good neuropathic pain drugs, the U.S. NIH ranks pain research as one of five major neurological research directions; the international pharmaceutical companies such as Asliking, li Lai and Hui Rui invest heavy gold and develop drugs for treating neuropathic pain with Nav1.7 and Nav1.8 as targets, which are not successful at present; the formula has good effect of inhibiting the brain pain by eye drops, has the same quick and efficient effect of inhibiting the pain by injection, and has the pain inhibition principle of 'approximate full substrate channel regulation mechanism' (optical channels may not be included and have nothing to do with concentration difference), the main components in the formula and the proportion of the main components, the preparation concentration and the proportion and the concentration of the components of additives; the approximate full substrate regulation mechanism can be met only by strict combination and keeping stable respective components, combination, proportion and concentration; when the high-concentration formula solution is close to the nervous system, a large amount of substrate transportation is needed for nerve cells, and the exchange modes of substances inside and outside the cells are mainly a vesicle-mediated transportation mode and a channel protein-mediated transmembrane transport mode (channel protein and transport protein); when 10% of the physiological saline drops on the wound, severe pain is caused, the cornea of the eye has a large number of nerve connections, the high concentration of the physiological saline may instantaneously rupture the cell membrane, and a large amount of cells die; however, the saturated concentration of the formulation solution of 26.47% is why the composition is instantly and actively absorbed into the brain without causing cell death and severe pain when applied to the eye, because there are many substrates, the substrates are simultaneously transported by vesicles and channel proteins, the multichannel opening and closing process achieves instant physical equilibrium, the cell membrane is not damaged, and pain is inhibited, because the channel is busy, pain signal transmission is blocked and hindered; the formula can inhibit brain glioma, cancer cells can be inhibited and eliminated by adopting eye drops, injection, a small amount of soaking and the like, a near-total substrate channel regulation mechanism can act on various cells of a human body, the regulation and control of a cancer cell transportation mode and the regulation and control of channel protein and transport protein of the cancer cells can be realized, the internal environment of the cancer cells is rapidly changed, the proliferation capacity of the cancer cells is destroyed, the difference between normal cells and the cancer cells can be amplified through the formula contact process, substances for controlling immune cells released by the cancer cells are eliminated, the cancer cells are rapidly identified and marked and are rapidly eradicated by the immune cells.
Setting a mathematical formula I by taking the numerical value of Na + ions as a reference; the contrast regeneration value = (formula solution ion saturation ÷ human or other animal mean body fluid concentration) ÷ { (human or other animal nerve cell membrane intramembrane concentration ÷ squid nerve cell intramembrane concentration + human or other animal nerve cell membrane external concentration) ÷ squid nerve cell membrane external concentration) ÷ 2}; the second mathematical formula: regeneration difficulty value (neuron ability value) = comparative regeneration value of human or other animal ÷ comparative regeneration value of squid (5.4); the calculated regeneration difficulty value of octopus is equal to 1, the regeneration difficulty value of cat is 10.21, and the regeneration difficulty value of man is 20.94; from this formula, it can be easily deduced that the regeneration difficulty value will spiral from 20.94 to 1 during the course of administration of the formulation, e.g. once a day; the process is a dynamic process and can be adjusted; the adjustable significance is that different formula amounts and times can be set for human nervous systems such as eyes, skin, various organ tissues and the like aiming at different diseases, and the diseases can be repaired and adjusted;
the formula is used for inhibiting pain, and the headache and fever of the brain, eye drop and atomization are carried out, wherein 0.1 ml of eye drop is used for each time, the eye drop is absorbed by eyes, 4 ml of atomization is carried out for each time, the atomization is carried out for 30 minutes, and after 30 minutes, the severe headache and fever can be relieved immediately; twice a day;
inhibiting toothache, and keeping the solution in mouth for more than 20 ml and two minutes to make the oral cavity tingle; can also be injected into the toothache part by 0.1 ml to relieve toothache immediately;
the injection is injected to 0.1 ml near the trigeminal nerve to feel numb and immediately relieve pain; or nasal drop, the solution is absorbed from nasal side to trigeminal nerve for 1 minute for relieving pain, but is ineffective for nasal side to trigeminal nerve, nerve route disorder or nasal drop damage; the injection can inhibit pain most quickly.
The injection can inhibit the pain of fall injury bone injury and muscle injury, and can directly inject 0.1-0.2 ml of the injection to cause the injection part to be scalded and numb, and then the pain is greatly reduced; the pain can be inhibited for 10-24 hours, and then the injection is continued according to the requirement;
the burn, scald and sunburn pain relieving agent is soaked in the solution for half an hour, so that the pain basically disappears, the wound recovery and repair are accelerated, and the scar generation is inhibited while the repair is carried out. For example, for the treatment of alopecia capitis, scalp immersion can be carried out with 26.47% solution for two months, 10 minutes each time and once a day; repairing nerves at the hair roots of the regenerated hair, and then growing hair villi; in the human body experiment, the patient is bald in 40% of the area of the top of the head, and the regrowth is successful by the method;
cancer inhibition cases: the injection is used for injecting 0.1 ml of formula solution every day, the area of the melanoma is about two square centimeters, and the melanoma completely disappears about 30 days;
the case of inhibiting the nerve atrophy:
the old has cramps on legs for years, and the cramps on the legs disappear after being treated by eye drops for 40 days after the old has cramps on the legs and is painful and awaken in the middle of the night every day.
For example, for inhibiting sexual dysfunction, 26.47% formula solution can be used for two months of skin smearing and eye dropping around sexual organ for supplementing neurotransmitter for central nervous system; accelerate nerve repair and immune system dredging, and restore sexual function; one of the benefits of this treatment is that the side effects are extremely low and negligible; the sense and function recovery is similar to that of teenagers, and the urinary function is similar to that of youth;
if insomnia is inhibited, the formula is used twice a day for dropping the eye, the sleep quality is rapidly improved along with the increase of the supplement delivery quality and the active peptide amount, and the sleep quality can be recovered to be normal; for example, depression can be inhibited, neurotransmitter can be rapidly and stably supplemented in mood through eye drops, and good mental state and resting sleep can be maintained;
for example, the aim is to inhibit muscle atrophy, and the muscle can be gradually increased by increasing the amount and frequency of the muscle growth; has effects in repairing and regenerating nerve, and promoting muscle growth; for example, the eye drops can promote the repair of the optic nerves and the peripheral nerves, and promote the growth of the peripheral muscles of the orbit, such as the orbicularis oculi muscles, the temporal muscles and other peripheral muscles; the mechanism of the formula for promoting muscle growth is that nerve injury is firstly repaired to promote repair and regeneration of nervous system injury, immunity is enhanced, excretion of metabolic waste is accelerated, and then vascular tissues and muscle tissues in tissues realize gradual growth. The gum muscle, the limb muscle and the whole body muscle are all suitable; it can be added into eye to calm and stabilize central nervous system, such as dizziness due to hunger, dizziness due to blood sugar deficiency, and long-term physical ability.
The treatment mode and the treatment method can be adjusted in significance by combining human experiments of specific implementation cases, accurately, stably and safely solve diseases through quantifiable and fixed character representation, and adjustable targets can be different targets such as longevity, muscle, even intelligence correlation, brain disease inhibition, cognitive disorder inhibition, poor concentration and the like.
In a specific use, the invention provides a central nervous system drug targeting a sodium ion channel chloride ion channel, according to the claim 1, in practical application, the formula of the invention is not limited to be used in human brain and eyes, can be used for treating diseases of tissues at any part of a human body, can be used for treating diseases of breeding animals and pets, can be applied to the whole human body in a mode of injection, smearing, dripping, atomizing, soaking, sticking and the like, can be prepared into a finished product mode, and comprises any pharmaceutically related production process modes and any combination of tablets, injection, atomizing, plasters, sticking, smearing, acupuncture point sticking, atomizing and spraying, bottled liquid, capsules and the like.
Any person skilled in the art can easily think of the splitting, adding changes or replacing of the formula within the technical scope of the invention, and the protection scope of the invention is covered. Therefore, the protection scope of the invention should be subject to the protection scope of the claims.

Claims (7)

1. A central nervous system medicine of a target sodium ion channel chloride ion channel comprises the following components: combining tea leaf components with sodium chloride; tea ingredients and sodium chloride, different tea ingredients are not very different, for example, the amino acids of tea are found to be more than 20, and the amino acid types, tea polyphenol content, inorganic matter types and the like of different tea are slightly different; the tea mainly comprises the following components: amino acids (theanine, asparagine, glutamic acid, glycine, serine, tryptophan, valine, histidine, arginine, threonine, alanine, proline, cysteine, tyrosine, methionine, lysine, isoleucine, leucine, phenylalanine, etc.) vitamins (C, B1, B2, B3, B5, B6, B11, B12, P1, H, a, D, E, K, etc.), alkaloids (caffeine, theophylline, theobromine, etc.), tea polyphenols (catechin, flavonoid, anthocyanidins, phenolic acids, etc.), fatty acid lipids (saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, phospholipids, glycerides, sulfatides, glycolipids, etc.), inorganic substances (potassium, phosphorus, calcium, magnesium, iron, sulfur, aluminum, fluorine, etc.); one of the formula solutions is that the salinity of sodium chloride reaches saturation (approximately equal to 26.47 percent) and is combined with the high concentration of the Tieguanyin tea components; the formula is an amino acid supplement drug and is also a neurotransmitter supplement drug.
2. The composition of claim 1, wherein said formulation targets the immune system, inhibits blockages in lymphatic vessels of the immune system, inhibits immune diseases, inhibits inflammatory storms; the formula is applied to eyes, so that firstly, inflammatory proteins in the eyes can be led out, secondly, eye drops can repair and dredge periocular lymph of the eyes to cerebral meninges lymph vessels, and mucus (cerebral metabolic waste) is rapidly discharged from pharyngeal walls and nasal cavities before and after a fixed position; the brain can produce interaction with periocular lymphatic vessels of peripheral immune system through meningeal lymphatic vessels to discharge cerebral metabolites, and inhibit brain diseases such as Alzheimer's Disease (AD); the formula is applied to any immune system part of the whole body, has fixed properties, dredges lymphatic vessels, secretes mucus at the fixed part, has large and more mucus secretion amount during inflammation, and has less mucus secretion amount reduced by inflammation.
3. The method of claim 1, wherein the formulation is one of the characteristics of the formulation applied to human body, such as targeting the central nervous system, the rapid linkage of nervous system and immune system, the formulation has fixed post-use properties in eyes, rectum, oral cavity, lung, skin, etc., mucus and fixed secretion site; the formula can inhibit central nervous system diseases and peripheral nervous system diseases.
4. The formulation of claim 1, wherein the highest concentration of sodium chloride (≈ 26.47%), one of the prerequisites for safe use of sodium and chloride ions in humans, is used in combination with a high concentration of tea ingredients; the formula targets a sodium ion channel and a chloride ion channel; targeting sodium ion channels is known to have 9 subunits (Nav1.1-1.9), such as targeting Nav1.7 and Nav1.8 inhibits neuropathic pain; targeting chloride channels is known to have 9 subunits (CLC 0-8), e.g., targeting CLC-3 inhibits tumors and inflammation.
5. The formulation of claim 1, wherein said formulation has strong hydrophobicity, inhibits the propagation of harmful viruses, inhibits the propagation of harmful bacteria in human body; the antibacterial mechanism is the transmembrane transport interaction and the amino acid target of high-concentration sodium ions and chloride ions, the antiviral mechanism is strong hydrophobicity and physically damages a virus membrane structure, inhibits the fusion of the virus membrane structure and human cells, the formula effect influences nerve cells and immune cells to quickly start immune enhancement, and inflammatory components of cells are quickly separated and discharged; the formula has the advantages of high efficiency of inhibiting bacteria and viruses, stable effect, high speed and low side effect of inhibiting mixed inflammation of bacteria and viruses.
6. The formulation of claim 1, wherein said formulation inhibits pain, inhibits hair loss, inhibits sexual dysfunction, inhibits cancer, inhibits nerve atrophy, inhibits muscle atrophy; one of the core mechanisms is to promote the concentration of sodium ions and chloride ions in the nerve cell membrane of a human body, the concentration of micromolecular neurotransmitters such as various amino acid concentrations and the like to be instantly improved, transfer the high-concentration sodium ions and chloride ions across the membrane, accelerate substance transportation and interaction and simultaneously act on multiple amino acid targets, reach or exceed the concentration of the sodium ions and chloride ions in the nerve cell membrane of regeneration-capable species such as squid octopus and the like, and trigger a repair and regeneration mechanism; the second core mechanism is that the nervous system and the immune system are linked together almost at the same time, and drug delivery and waste output are completed in a short time; while pain is minimal; the mechanism of the formula for promoting muscle growth is that nerve injury is firstly repaired to promote repair and regeneration of nervous system injury, immunity is enhanced, excretion of metabolic waste is accelerated, and then vascular tissues and muscle tissues in tissues realize gradual growth.
7. According to claim 1, in practical applications, the formulation of the present invention is not limited to be used in brain and eye of human beings, and can be used in the treatment of diseases of any tissue of human body, and can also be used in the treatment of diseases of cultured animals and pets.
CN202111141883.4A 2021-09-27 2021-09-27 Central nervous system medicine of targeted sodium ion channel chloride ion channel Pending CN115869364A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111141883.4A CN115869364A (en) 2021-09-27 2021-09-27 Central nervous system medicine of targeted sodium ion channel chloride ion channel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111141883.4A CN115869364A (en) 2021-09-27 2021-09-27 Central nervous system medicine of targeted sodium ion channel chloride ion channel

Publications (1)

Publication Number Publication Date
CN115869364A true CN115869364A (en) 2023-03-31

Family

ID=85763346

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202111141883.4A Pending CN115869364A (en) 2021-09-27 2021-09-27 Central nervous system medicine of targeted sodium ion channel chloride ion channel

Country Status (1)

Country Link
CN (1) CN115869364A (en)

Similar Documents

Publication Publication Date Title
ES2278393T3 (en) ANTIMICROBIAL TREATMENT OF VIRUS HERPES SIMPLEX AND OTHER INFECTIOUS DISEASES.
CA3146050A1 (en) Metered dosing compositions and methods of use of psychedelic compounds
WO2014031964A1 (en) Composition for the treatment of migraine headaches
DE60315258T2 (en) TREATMENT OF NON-PAINTING BLADDER TROUBLESHOOTING WITH MODULATORS OF THE ALPHA 2 DELTA SUB-UNIT OF THE CALCIUM CHANNEL
CN111544390B (en) Traditional Chinese medicine preparation for treating meibomian gland dysfunction and/or allergic conjunctivitis, ultrasonic atomization and nano-spray preparation and preparation method
CN105106318B (en) A kind of Chinese medicine composition and preparation method thereof for treating xerophthalmia
US20240189382A1 (en) Formula for inhibiting aging regeneration repair
CN115869364A (en) Central nervous system medicine of targeted sodium ion channel chloride ion channel
CN103933198B (en) A kind of active mineral ion profit eye liquid
CA2939623A1 (en) Nasal and sinus wash compositions and methods
CN113318038A (en) Acne-removing and anti-inflammatory sophora alopecuroide total alkaloid mask and preparation method thereof
CN115671188A (en) Technical formula for active absorption of amino acid by eyes
CN115957269A (en) Formula for targeted mucus inhibition of cancer
CN101322717A (en) Medicament composition for preventing and treating eye diseases
CN116785359A (en) Human tissue and organ repair and regeneration formula
CN116763853A (en) Formula for inhibiting brain and eye diseases
Ghosh et al. Exploring the therapeutic potential of natural ingredients for eye health: A comprehensive review
CN118236432A (en) Sodium ion numerical value regulation formula
CN116459323B (en) Essential oil composition for dysosmia and application thereof
CN107519309A (en) A kind of ophthalmic combined complete
CN116803408A (en) Formula for inhibiting sexual dysfunction
CN116785360A (en) Formula for inhibiting cancers
Katru et al. Application Of Charak Samhita Matrasitiya Adhyaya (Quantitative Dietetics) In The Maintenance Of Health
RU2200561C1 (en) Method for treating and preventing diseases
CN111184768A (en) Traditional Chinese medicine composition for treating exophthalmos and preparation method and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication