CN1158530C - 多层测试柱 - Google Patents

多层测试柱 Download PDF

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Publication number
CN1158530C
CN1158530C CNB998010111A CN99801011A CN1158530C CN 1158530 C CN1158530 C CN 1158530C CN B998010111 A CNB998010111 A CN B998010111A CN 99801011 A CN99801011 A CN 99801011A CN 1158530 C CN1158530 C CN 1158530C
Authority
CN
China
Prior art keywords
multicolumn
chamber
layer
thin layer
fluid sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB998010111A
Other languages
English (en)
Chinese (zh)
Other versions
CN1273638A (zh
Inventor
陈叔奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Molecular Systems Ltd
Original Assignee
Chen and Chen LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chen and Chen LLC filed Critical Chen and Chen LLC
Publication of CN1273638A publication Critical patent/CN1273638A/zh
Application granted granted Critical
Publication of CN1158530C publication Critical patent/CN1158530C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • G01N2030/524Physical parameters structural properties
    • G01N2030/527Physical parameters structural properties sorbent material in form of a membrane
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1055General features of the devices using the transfer device for another function for immobilising reagents, e.g. dried reagents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6052Construction of the column body
    • G01N30/6082Construction of the column body transparent to radiation

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Memory System Of A Hierarchy Structure (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CNB998010111A 1998-06-24 1999-06-23 多层测试柱 Expired - Lifetime CN1158530C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9046998P 1998-06-24 1998-06-24
US06/090,469 1998-06-24

Publications (2)

Publication Number Publication Date
CN1273638A CN1273638A (zh) 2000-11-15
CN1158530C true CN1158530C (zh) 2004-07-21

Family

ID=22222904

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998010111A Expired - Lifetime CN1158530C (zh) 1998-06-24 1999-06-23 多层测试柱

Country Status (10)

Country Link
US (1) US20040105782A1 (https=)
EP (1) EP1004025B1 (https=)
JP (1) JP2002519643A (https=)
CN (1) CN1158530C (https=)
AT (1) ATE257944T1 (https=)
AU (1) AU4827999A (https=)
CA (1) CA2301077C (https=)
DE (1) DE69914164T2 (https=)
ES (1) ES2214865T3 (https=)
WO (1) WO1999067647A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
US20030032029A1 (en) * 1998-12-21 2003-02-13 Nanogen, Inc. Three dimensional apparatus and method for integrating sample preparation and multiplex assays
EP1218743B1 (en) * 1999-07-26 2006-05-31 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Layered device with capture regions for cellular analysis
US7214477B1 (en) 1999-07-26 2007-05-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Layered device with capture regions for cellular analysis
CA2438137A1 (en) * 2001-02-13 2002-08-22 Universiteit Gent Device and method for detecting the presence of an analyte
CA2460192C (en) 2001-09-11 2011-04-19 Iquum, Inc. Sample vessels
US20060147926A1 (en) 2002-11-25 2006-07-06 Emmert-Buck Michael R Method and apparatus for performing multiple simultaneous manipulations of biomolecules in a two-dimensional array
CA2515075C (en) * 2003-02-05 2012-10-02 Iquum, Inc. Sample processing
US20070017870A1 (en) 2003-09-30 2007-01-25 Belov Yuri P Multicapillary device for sample preparation
JP2008505346A (ja) * 2004-06-07 2008-02-21 アイキューム, インク. サンプルマルチ処理
DE102005005437A1 (de) * 2005-02-05 2006-08-10 Eppendorf Ag Filterpipettenspitze
US20080003564A1 (en) * 2006-02-14 2008-01-03 Iquum, Inc. Sample processing
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2435511A (en) 2006-02-23 2007-08-29 Mologic Ltd Protease detection
DK3517151T3 (da) * 2006-03-09 2021-07-12 Aethlon Medical Inc Ekstrakorporal fjernelse af mikrovesikulære partikler
JP5156738B2 (ja) 2006-06-06 2013-03-06 エフ.ホフマン−ラ ロシュ アーゲー 全血試料の特異的溶血
US20080113357A1 (en) * 2006-06-29 2008-05-15 Millipore Corporation Filter device for the isolation of a nucleic acid
JP4935424B2 (ja) * 2007-02-28 2012-05-23 東レ株式会社 免疫分析チップ
JP2011517773A (ja) * 2008-03-28 2011-06-16 バイオティクス, インコーポレイテッド サンプル調製デバイスおよび分析物の処理方法
CN102841167A (zh) * 2011-06-20 2012-12-26 苏州赛分科技有限公司 一种液相吸附色谱分离柱
WO2015048769A1 (en) * 2013-09-30 2015-04-02 Board Of Regents, The University Of Texas System Method and apparatus for scanning detection
US11260386B2 (en) 2015-06-05 2022-03-01 The Emerther Company Component of a device, a device, and a method for purifying and testing biomolecules from biological samples
CN115639365B (zh) * 2016-07-25 2026-01-02 生物辐射实验室股份有限公司 侧流装置及使用方法
WO2020214224A1 (en) * 2019-04-18 2020-10-22 Siemens Healthcare Diagnostics Inc. Integrated microfluidic device with pipette adaptation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2942674B1 (de) * 1979-10-23 1981-05-07 Drägerwerk AG, 2400 Lübeck Pruefroehrchen zur Messung von Nickel-Aerosolen
EP0139373A1 (en) * 1983-08-26 1985-05-02 The Regents Of The University Of California Multiple immunoassay system
US5057438A (en) * 1986-09-24 1991-10-15 Agency Of Industrial Science And Technology Electrophoretic antigen-antibody determination with laminate of multiple membranes
US4874691A (en) * 1987-10-16 1989-10-17 Quadra Logic Technologies Inc. Membrane-supported immunoassays
US5438128A (en) * 1992-02-07 1995-08-01 Millipore Corporation Method for rapid purifiction of nucleic acids using layered ion-exchange membranes
US5876918A (en) * 1993-03-08 1999-03-02 Hydros, Inc. Aligned fiber diagnostic chromatography with positive and negative controls

Also Published As

Publication number Publication date
WO1999067647A1 (en) 1999-12-29
DE69914164D1 (de) 2004-02-19
EP1004025A1 (en) 2000-05-31
EP1004025B1 (en) 2004-01-14
ATE257944T1 (de) 2004-01-15
AU4827999A (en) 2000-01-10
JP2002519643A (ja) 2002-07-02
CA2301077A1 (en) 1999-12-29
CN1273638A (zh) 2000-11-15
DE69914164T2 (de) 2004-11-25
CA2301077C (en) 2010-05-25
ES2214865T3 (es) 2004-09-16
US20040105782A1 (en) 2004-06-03

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CI01 Publication of corrected invention patent application

Correction item: Priority

Correct: 1998.06.24 US 60/090,469

False: 1998.06.24 US 06/090,469

Number: 29

Page: 460

Volume: 20

CI03 Correction of invention patent

Correction item: Priority

Correct: 1998.06.24 US 60/090,469

False: 1998.06.24 US 06/090,469

Number: 29

Page: The title page

Volume: 20

COR Change of bibliographic data

Free format text: CORRECT: PRIORITY; FROM: 1998.6.24 US 06/090,469 TO: 1998.6.24 US 60/090,469

ERR Gazette correction

Free format text: CORRECT: PRIORITY; FROM: 1998.6.24 US 06/090,469 TO: 1998.6.24 US 60/090,469

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160706

Address after: American California

Patentee after: Roche Molecular Systems Ltd

Address before: Massachusetts, USA

Patentee before: Chen & Chen LLC

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20040721