CN115844491B - Thrombolysis device with controllable retraction and expansion of thrombolysis net - Google Patents

Thrombolysis device with controllable retraction and expansion of thrombolysis net Download PDF

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Publication number
CN115844491B
CN115844491B CN202310139023.XA CN202310139023A CN115844491B CN 115844491 B CN115844491 B CN 115844491B CN 202310139023 A CN202310139023 A CN 202310139023A CN 115844491 B CN115844491 B CN 115844491B
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tube
thrombus
net
action
cylinder
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CN115844491A (en
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荆洪娟
黄嘉平
柯长奋
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Hangzhou Yike Medical Technology Co ltd
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Hangzhou Yike Medical Technology Co ltd
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Priority to PCT/CN2023/130977 priority Critical patent/WO2024120117A1/en
Priority to US18/529,981 priority patent/US20240180574A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22094Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for crossing total occlusions, i.e. piercing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention discloses a thrombus taking device with controllable thrombus taking net shrinkage and expansion, which comprises a thrombus taking net, a pushing tube and a thrombus taking tube, wherein the thrombus taking tube is provided with a tube cavity for accommodating the thrombus taking net and the pushing tube, the thrombus taking net is provided with a shrinkage state with radial shrinkage and an expansion state with radial expansion, the proximal end of the thrombus taking net is fixedly connected with the distal end of the pushing tube, the thrombus taking device also comprises an action tube provided with a first action block and a second action block, the first action block and the second action block are both fixed on the action tube and are arranged at intervals, the distal end of the thrombus taking net is sleeved on the action tube and can slide in a spacing range defined between the first action block and the second action block, and when the action tube is configured to move along a preset direction and generate relative displacement with the pushing tube, the thrombus taking net is driven to shrink along the radial direction or drive the thrombus taking net to expand along the radial direction through the first action block.

Description

Thrombolysis device with controllable retraction and expansion of thrombolysis net
Technical Field
The invention relates to the technical field of medical equipment, in particular to a thrombus taking device with a thrombus taking net capable of being controlled in shrinkage and expansion.
Background
Mechanical thrombus removal is to deliver a thrombus remover to a lesion site to capture thrombus and finally remove the thrombus from the body. Existing mechanical thrombolysis generally includes: thrombectomy, laser thrombus breaking and capture device thrombus taking, wherein the thrombectomy thrombus taking is thorough, but the damage to the vessel wall is too large, various concurrent inflammations are very easy to cause, the laser thrombus breaking operation is difficult, the laser energy is ineffective when the laser energy is too low, the blood vessel is damaged when the energy is too high, and various complications are also easy to cause, so the capture device thrombus taking is most commonly used at present.
The capturing device is to achieve the thrombus taking by utilizing a thrombus taking net with automatic expansion performance, for example, CN104068911A discloses a blood vessel thrombus taking device and a thrombus taking device, wherein the thrombus taking net is conveyed to an intravascular lesion position and released, the thrombus taking net is positioned by a developing mark on the thrombus taking net, the elastic acting force of the thrombus taking net is gradually expanded to be attached to the blood vessel wall, finally, the thrombus taking net is retracted to capture thrombus, and the thrombus taking net is withdrawn from the human body to finish thrombus taking. Because the CN104068911a fully utilizes the self-expansion property of the thrombolytic mesh to realize the contraction and expansion, when facing the blood vessel with complex lesions, for example, the thrombus in the blood vessel is too hard, the thrombolytic mesh is not necessarily expanded smoothly, i.e. the situation that the thrombolytic device cannot be opened occurs, at this time, the thrombolysis failure is caused or the thrombolysis effect is poor.
Disclosure of Invention
The invention aims to solve the technical problems in the prior art, and provides a thrombus taking device with controllable thrombus taking net shrinkage and expansion, so as to overcome the technical defects that the thrombus taking device is completely dependent on the expansion performance of the thrombus taking net to realize shrinkage and expansion in the prior art, and thus, the thrombus taking failure is easy to cause or the thrombus taking effect is poor.
According to the invention, there is provided a thrombus removing device with controllable shrinkage and expansion of a thrombus removing net, comprising a thrombus removing net, a pushing tube and a thrombus removing tube, wherein the thrombus removing tube is provided with a tube cavity for accommodating the thrombus removing net and the pushing tube, the thrombus removing net is provided with a shrinkage state with radial shrinkage and an expansion state with radial expansion, a proximal end of the thrombus removing net is fixedly connected with a distal end of the pushing tube, the thrombus removing device further comprises an action tube provided with a first action block and a second action block, the first action block and the second action block are both fixed on the action tube and are arranged at intervals, the distal end of the thrombus removing net is sleeved on the action tube and can slide in a spacing range defined between the first action block and the second action block, and when the action tube is configured to move along a preset direction and generate relative displacement with the pushing tube, the thrombus removing net is driven to shrink along the radial direction or driven to expand the thrombus removing net along the radial direction through the first action block.
Further, the proximal end of the thrombus removing net is an open end, the distal end of the thrombus removing net is fixedly connected with a sliding block and is converged on the sliding block to form a furled end, and the sliding block is sleeved on the acting pipe and is configured to slide in a spacing range defined between the first acting block and the second acting block.
Further, the first action block is located in the thrombus taking net, and when the action tube is pushed in the direction from the proximal end to the distal end and relatively displaced with the pushing tube, the sliding block can be driven by the first action block to slide in the direction from the distal end, so that the thrombus taking net is extended to be contracted in the radial direction.
Further, the second action block is located outside the thrombus removing net, and when the action tube is pulled in the distal end to the proximal direction and generates relative displacement with the pushing tube, the second action block can drive the sliding block to slide in the proximal direction, so that the thrombus removing net is shortened to expand in the radial direction.
Further, action pipe and propelling movement pipe coaxial setting, action pipe are located the propelling movement intraductal at least partially, and the proximal end fixedly connected with spacing urceolus of propelling movement pipe, the proximal end fixedly connected with spacing pull rod of action pipe.
Further, the limiting pull rod is fixedly connected with the limiting outer cylinder in a sliding clamping manner; or the limiting pull rod is rotationally clamped and fixed with the limiting outer cylinder, and the acting pipe can also rotate relative to the distal end of the thrombus taking net.
Further, spacing urceolus includes first barrel, second barrel, first barrel seat and second barrel seat, and first barrel, second barrel seat butt joint each other form the barrel, and first barrel seat and second barrel seat are fixed respectively at the proximal end and the distal end of barrel, are equipped with first barrel chamber in the first barrel seat, are equipped with the second barrel chamber in the second barrel seat, and spacing pull rod and first barrel chamber, second barrel chamber all slide and rotate to be connected, and the spacing inner tube that fixedly connected with has spacing draw-in groove in the barrel is equipped with the spacing fixture block with spacing draw-in groove joint on the spacing pull rod.
Further, the proximal ends of the first half cylinder and the second half cylinder are respectively provided with a proximal clamping groove, the first cylinder seat is provided with two proximal clamping blocks clamped with the proximal clamping grooves, the two proximal clamping blocks are symmetrically arranged on the butt joint surfaces of the first half cylinder and the second half cylinder in a butt joint mode, and/or the distal ends of the first half cylinder and the second half cylinder are respectively provided with a distal clamping groove in a relative mode, the second cylinder seat is provided with two distal clamping blocks clamped with the distal clamping grooves, and the two distal clamping blocks are symmetrically arranged on the butt joint surfaces of the first half cylinder and the second half cylinder in a butt joint mode.
Further, the pushing tube is fixedly connected with the second tube seat and is communicated with the second tube cavity, a first sealing ring for sealing between the second tube cavity and the inside of the tube body is sleeved on the acting tube, and a first injection pipeline communicated with the second tube cavity is arranged outside the second tube seat.
Further, a thrombus taking tube seat is fixed at the proximal end of the thrombus taking tube, a second sealing ring for sealing the inside and the outside of the thrombus taking tube seat is sleeved on the pushing tube, and a second injection pipeline communicated with the lumen is arranged outside the thrombus taking tube seat.
Compared with the prior art, the invention has the advantages that the first action block and the second action block are arranged on the action tube at intervals, and the first action block and the second action block drive the thrombus taking net to shrink and expand radially, so that the thrombus taking net is controllable in shrinkage and expansion, the thrombus taking net can not shrink after the thrombus taking is finished to avoid the failure of withdrawing the blood vessel smoothly, the thrombus taking net can not expand the wall in the blood vessel to avoid the failure of complete thrombus taking, the distal end of the thrombus taking net can move towards the second action block relative to the action tube to shrink further after the thrombus taking net shrinks, and the distal end of the thrombus taking net can move towards the first action block relative to the action tube to expand further after the thrombus taking net expands, thereby the distal end position of the thrombus taking net is not limited completely, and the thrombus volume and other conditions in the thrombus taking net can be dynamically regulated, so that the thrombus can be regulated in the thrombus taking net automatically to realize uniform distribution, and the thrombus taking effect is improved.
Drawings
The invention will be more fully understood and its attendant advantages and features will be more readily understood by reference to the following detailed description, taken in conjunction with the accompanying drawings.
Fig. 1 is a schematic structural view of a thrombolytic device with a thrombolytic mesh in an expanded state and outside a thrombolytic tube.
Fig. 2 is a schematic structural view of a thrombolytic device with a thrombolytic mesh in a contracted state and outside a thrombolytic tube.
Fig. 3 is a schematic view of the thrombolytic device with the thrombolytic mesh in a contracted state and positioned in the thrombolytic tube.
Fig. 4 is a schematic perspective view of the thrombolytic mesh and push tube of fig. 1.
Fig. 5 is a schematic view of the deployed configuration of the embolic net and push tube of fig. 1.
Fig. 6 is a schematic structural view of the limiting mechanism in fig. 1.
Fig. 7 is a cross-sectional view of fig. 6.
Fig. 8 is an enlarged view at a in fig. 7.
Fig. 9 is an exploded view of fig. 6.
FIG. 10 is a schematic view of the spacing rod and inner barrel of FIG. 9.
Fig. 11 is an exploded view of the check rod of fig. 10.
FIG. 12 is a schematic view of the inner barrel of FIG. 10.
Fig. 13 is a cross-sectional view of the spacing mechanism of fig. 2.
Fig. 14 is a schematic view of the limiting mechanism of fig. 2 with the first and second half cylinders removed.
Fig. 15-19 are schematic views of a thrombus removal procedure of the thrombus removal device.
Fig. 20 is a prior art schematic.
In the accompanying drawings: 1 is a bolt taking tube, 2 is a pushing tube, 3 is an acting tube, 4 is a bolt taking net, 5 is a tube cavity, 6 is a first acting block, 7 is a second acting block, 8 is a sliding block, 9 is a limit outer tube, 10 is a limit pull rod, 11 is a first half tube, 12 is a second half tube, 13 is a first tube seat, 14 is a second tube seat, 15 is a proximal clamping groove, 16 is a proximal clamping block, 17 is a distal clamping groove, 18 is a distal clamping block, 19 is an inner tube, 20 is a connecting protrusion, 21 is a connecting groove, 22 is a track sliding groove, 23 is a limit clamping groove, 24 is a limit clamping block, 25 is a first tube cavity, 26 is a second tube cavity, 27 is a limit pull handle, 28 is a first injection tube, 29 is a bolt taking tube seat, 30 is a second injection tube, 31 is a first sealing ring, 32 is a second sealing ring, 33 is a reset spring, 34 is a limit block, 35 is a connecting column, 36 is a connecting tube, 37 is a safety protrusion, 38 is a safety hole, 39 is a groove, 40 is a first bolt taking net, 41 is a second bolt taking net, and 43 is acted on the second end; 100 is a blood vessel, 200 is a thrombus, and 300 is a sheath.
It should be noted that the drawings are for illustrating the invention and are not to be construed as limiting the invention. Note that the drawings representing structures may not be drawn to scale. Also, in the drawings, the same or similar elements are denoted by the same or similar reference numerals.
Description of the embodiments
In order that the invention may be more readily understood, a detailed description of the invention is provided below along with specific embodiments and accompanying figures.
The terms "proximal" and "distal" in the sense of the present invention should be understood as meaning, viewed from the direction of the attending physician, the term "proximal" referring to the end proximal to the attending physician, i.e. corresponding to the "left end" referred to with reference to the accompanying drawings, and the term "distal" referring to the end distal to the attending physician, i.e. corresponding to the "right end" referred to with reference to the accompanying drawings.
The thrombus removing device of the embodiment is inserted into a blood vessel through a sheath tube to remove thrombus, one part of the sheath tube is penetrated in the blood vessel, and the other part of the sheath tube is exposed out of the blood vessel. The structure of the thrombus removing device is shown in fig. 1 to 14, and the thrombus removing device comprises a thrombus removing tube 1, a pushing tube 2, an acting tube 3, a thrombus removing net 4 and a limiting mechanism, wherein the thrombus removing tube 1 is provided with a tube cavity 5 for accommodating the pushing tube 2 and the thrombus removing net 4, the pushing tube 2 and the acting tube 3 are hollow tubes, so that a pushing guide wire can conveniently pass through, the acting tube 3 is at least partially arranged in the pushing tube 2 in a sliding manner, the thrombus removing net 4 is a self-expanding net and is provided with a plurality of meshes, the thrombus removing net 4 is in a radially contracted and expanded state, the proximal end of the thrombus removing net 4 is an open end, the distal end of the thrombus removing net 4 is a closed end, when the thrombus removing net 4 is positioned in a blood vessel and moves from the distal end to the proximal end, thrombus in the blood vessel can be separated and collected, the proximal end of the thrombus removing net 4 is fixedly connected with the distal end of the pushing tube 2, the thrombus removing net 4 can be pushed into the blood vessel, the thrombus removing net 4 can be removed, and the thrombus removing net 4 can be removed into the blood vessel.
The action tube 3 is provided with a first action block 6 and a second action block 7, the first action block 6 and the second action block 7 are fixed on the action tube 3 and are arranged at intervals, the distal end of the thrombus removing net 4 is sleeved on the action tube 3 and can slide in a spacing range defined between the first action block 6 and the second action block 7, when the action tube 3 is configured to move along a preset direction and generate relative displacement with the pushing tube 2, the thrombus removing net 4 is driven to shrink in the radial direction by the first action block 6 or the thrombus removing net 4 is driven to expand in the radial direction by the second action block 7, thus compared with the prior art, the embodiment can prevent the thrombus removing net 4 from shrinking after the thrombus removing is finished and leading to the failure to withdraw from blood vessels smoothly, the distal end of the thrombus removing net 4 can also be moved towards the second action block 7 to further contract relative to the action tube 3 after the thrombus removing net 4 contracts, and the distal end of the thrombus removing net 4 can be moved towards the first action block 6 to further expand relative to the action tube 3 after the thrombus removing net 4 expands, so that the distal end position of the thrombus removing net 4 is not completely limited, and the thrombus volume and other conditions in the thrombus removing net 4 can be dynamically regulated, so that the thrombus can be uniformly distributed in the thrombus removing net 4 at the automatic regulation position, and the thrombus removing effect of the embodiment is improved.
The distal end of the thrombus removing net 4 is fixedly connected with a sliding block 8 and is converged on the sliding block 8 to form a furled end, and the sliding block 8 is sleeved on the acting tube 3 and is configured to slide in the interval range of the acting tube 3 defined between the first acting block 6 and the second acting block 7 and also can rotate relative to the acting tube 3. The first action block 6 is located in the thrombus removing net 4, the second action block 7 is located outside the thrombus removing net 4, when the action tube 3 is pushed in the proximal direction and generates relative displacement with the pushing tube 2, the pushing tube 3 can drive the sliding block 8 to slide in the distal direction through the first action block 6 so that the thrombus removing net 4 is extended to shrink in the radial direction, and when the action tube 3 is pulled in the distal direction and generates relative displacement with the pushing tube 2, the pushing tube 3 can drive the sliding block 8 to slide in the proximal direction through the second action block 7 so that the thrombus removing net 4 is shortened to expand in the radial direction.
The first action block 6 is an annular boss protruding out of the outer surface of the action tube 3, the annular boss is fixed with the action tube 3 in a split mode, the first action block 6 further plays a supporting role in supporting the thrombus taking net 4, a certain thrombus accommodating space can be reserved when the thrombus taking net 4 is in a radial shrinkage state, thrombus in the thrombus taking net 4 is prevented from being extruded due to the fact that the thrombus accommodating space is too small, thrombus is prevented from escaping, the thrombus is prevented from being taken out completely, and particularly, after the action tube 3 moves in the direction from the proximal end to the distal end and moves for a preset displacement relative to the pushing tube 2, the first action block 6 moves to be in contact with the distal end of the thrombus taking net 4, and at least partially props up the distal end of the thrombus taking net 4. And because the first action block 6 is arranged to protrude out of the outer surface of the action tube 3, the first action block 6 can also gather part of thrombus in the thrombus taking net 4, and can effectively prevent thrombus at the far end of the thrombus taking net 4 from moving to the near end so as to reduce the thrombus cutting efficiency at the near end. The second action block 7 is also an annular boss protruding out of the outer surface of the action tube 3, the distal end of the second action block 7 is formed into a conical end, thrombus is convenient to penetrate, and after the thrombus taking net 4 is contained in place in the lumen 5 of the thrombus taking tube 1, the second action block 7 is clamped at the distal end of the thrombus taking tube 1.
The radial contraction and radial expansion of the thrombus removing net 4 in this embodiment can be achieved by manipulating the action tube 3, after the thrombus removing net 4 is completed and before the thrombus removing net 4 is completely retracted into the sheath tube, the thrombus removing net 4 is configured to have at least a stage in which the whole thrombus removing net 4 is in a contracted state, that is, the whole thrombus removing net 4 after the thrombus removing is in a radially contracted state and is completely retracted into the sheath tube, so that the thrombus removing net 4 is in a radially expanded state to separate and store thrombus in a blood vessel, and the thrombus removing net 4 is in a contracted state to reduce the radial size after the thrombus removing is completed, so that the thrombus removing net 4 with thrombus can be smoothly retracted into the sheath tube to withdraw from the blood vessel, and in the process of the whole radial contraction of the thrombus removing net 4, the thrombus in the thrombus removing net 4 can be radially extruded so as to enable the thrombus in the thrombus removing net 4 to be axially displaced, and finally, the thrombus in the thrombus removing net 4 is relatively uniform in distribution, and the thrombus in the thrombus removing net 4 is not gathered at a certain place so that the radial size of the place is not rubbed and the thrombus is not extruded and escaped from the inner wall of the sheath tube.
The limiting mechanism is arranged between the pushing tube 2 and the acting tube 3 and allows the acting tube 3 to move relative to the pushing tube 2 by a preset displacement, after the acting tube 3 moves relative to the pushing tube 2 from the proximal end to the distal end by the preset displacement, the thrombus taking net 4 is in a minimum shrinkage state of radial shrinkage, and at the moment, if the acting tube 3 moves relative to the pushing tube 2 from the distal end to the proximal end by the preset displacement, the thrombus taking net 4 is restored to be expanded to be in an expansion state. The limiting mechanism comprises a limiting outer cylinder 9 and a limiting pull rod 10 which are coaxially arranged and can be locked relatively, wherein the limiting pull rod 10 and the limiting outer cylinder 9 can be in sliding clamping connection or in rotary clamping connection for locking, in the embodiment, the limiting pull rod 10 and the limiting outer cylinder 9 are in rotary clamping connection and fixed, the limiting outer cylinder 9 is fixedly connected with the proximal end of the pushing tube 2, and the limiting pull rod 10 is fixedly connected with the proximal end of the acting tube 3. Specifically, the limiting outer cylinder 9 comprises a first half cylinder 11, a second half cylinder 12, a first cylinder seat 13 and a second cylinder seat 14, the first half cylinder 11 and the second half cylinder 12 are mutually abutted to form a cylinder body, the first half cylinder 11 and the second half cylinder 12 are symmetrically arranged relative to an abutting surface, the first cylinder seat 13 and the second cylinder seat 14 are respectively and symmetrically arranged at the near end and the far end of the cylinder body, the near end of the first half cylinder 11 and the near end of the second half cylinder 12 are respectively and oppositely provided with a near end clamping groove 15, the far end of the first cylinder seat 13 is provided with two near end clamping blocks 16 which are clamped with the near end clamping groove 15, the two near end clamping blocks 16 are configured to be symmetrically arranged relative to the abutting surface of the first half cylinder 11 and the abutting surface of the second half cylinder 12, the far end of the first half cylinder 11 and the far end of the second half cylinder 12 are respectively and oppositely provided with a far end clamping groove 17, the near end clamping blocks 18 which are clamped with the far end clamping grooves 17 are respectively, the near end clamping blocks 18 are arranged relative to the near end of the first half cylinder 11 and the second half cylinder 12, the far end clamping blocks 12 can be mutually and rapidly arranged at the abutting surfaces of the first half cylinder 11 and the abutting surface of the second half cylinder 12, the far end clamping blocks can be mutually clamped between the far end and the far end clamping blocks 16 and the far end of the first half cylinder 11 and the far end of the cylinder body, and the far end of the cylinder body is rapidly arranged between the far end clamping blocks and the far end clamping blocks, and the far end clamping blocks and near end clamping blocks and the far end between the far end clamping blocks and near end cylinder bodies and near end cylinder bodies and near end respectively, and near ends respectively. The inner cylinder 19 is fixedly connected in the limiting outer cylinder 9, namely the cylinder body, the inner cylinder 19 is installed in the cylinder body through the connecting lug 20 and the connecting groove 21, the connecting lug 20 is fixed on the inner wall of the first half cylinder body 11 and/or the second half cylinder body 12, the connecting groove 21 is positioned on the outer wall of the inner cylinder 19, or the connecting groove 21 is positioned on the inner wall of the first half cylinder body 11 and/or the second half cylinder body 12, the connecting lug 20 is positioned on the outer wall of the inner cylinder 19, the inner cylinder 19 is provided with the track sliding groove 22 and the limiting clamping groove 23, the track sliding groove 22 and the limiting clamping groove 23 are separately arranged and mutually communicated, the limiting clamping block 24 is arranged on the limiting pull rod 10, and the limiting clamping block 24 can be matched on the track sliding groove 22 and slide along the track sliding groove 22, so that the limiting pull rod 10 can slide relative to the limiting outer cylinder 9 and can be matched in the limiting clamping groove 23 after rotating, so that the limiting pull rod 10 is locked relative to the limiting outer cylinder 9.
The first cylinder seat 13 is internally provided with a first cylinder cavity 25, the second cylinder seat 14 is internally provided with a second cylinder cavity 26, the limit pull rod 10 penetrates through the first cylinder cavity 25 and the second cylinder cavity 26, the limit pull rod 10 is in sliding and rotating connection with the first cylinder cavity 25 and the second cylinder cavity 26, the proximal end of the limit pull rod 10 is fixedly connected with a limit pull handle 27 so as to conveniently pull the limit pull rod 10, the distal end of the limit pull rod 10 penetrates through the first cylinder cavity 25, the inner cylinder 19 and the second cylinder cavity 26 and is relatively and fixedly connected with the proximal end of the acting tube 3, the proximal end of the acting tube 3 penetrates through the proximal end of the limit pull rod 10 and is fixed in the limit pull handle 27, the inside of the limit pull handle 27 is communicated with the inside of the acting tube 3 so as to conveniently penetrate through a push guide wire, the distal end of the second cylinder seat 14 is fixedly connected with the proximal end of the push tube 2, the second cylinder cavity 26 is communicated with the push tube 2, the outside of the second cylinder seat 14 is provided with a first injection pipeline 28 communicated with the second cylinder cavity 26, the proximal end of the thrombus taking tube 1 is fixedly provided with a thrombus taking tube seat 29, the thrombus taking tube seat 29 is arranged close to the distal end of the second cylinder seat 14 and is detachably connected with the distal end of the second cylinder seat 14, the outside of the thrombus taking tube seat 29 is provided with a second injection pipeline 30 communicated with the tube cavity 5 of the thrombus taking tube 1, thus the first injection pipeline 28 is communicated with the inside of the pushing tube 2 through the second cylinder cavity 26, the second injection pipeline 30 is communicated with the inside of the thrombus taking tube 1 through the thrombus taking tube seat 29, the first injection pipeline 28 and the second injection pipeline 30 are used for injecting physiological saline, contrast agent and the like, in order to prevent the injection liquid injected in the first injection pipeline 28 from flowing into the inside of the cylinder body from the second cylinder cavity 26 and the injection liquid injected in the second injection pipeline 30 from flowing out from the inside of the thrombus taking tube seat 29, in this embodiment, the action tube 3 is sleeved with a first sealing ring 31 for sealing between the second barrel cavity 26 and the inside of the barrel, and the push tube 2 is sleeved with a second sealing ring 32 for sealing between the inside and the outside of the thrombus taking tube seat 29, wherein the first sealing ring 31 and the second sealing ring 32 are both 0-type sealing rings.
The limiting pull rod 10 is further provided with a reset spring 33 which drives the limiting pull rod 10 to reset after the limiting clamping block 24 is separated from the limiting clamping groove 23, the far end of the limiting pull rod 10 is provided with a limiting block 34 in a clamping manner, the limiting clamping block 24 is fixed on the outer surface of the limiting block 34, one end, close to the limiting pull rod 10, of the limiting block 34 is fixedly provided with a connecting column 35 and a connecting cylinder 36, the connecting column 35 is located inside the connecting cylinder 36, a connecting cavity for inserting the far end of the limiting pull rod 10 is formed between the connecting column 35 and the connecting cylinder, in order to conveniently and firmly fix the far end of the limiting pull rod 10 with the limiting block 34, the outer surface of the connecting column 35 is provided with a safety protrusion 37, the far end of the limiting pull rod 10 is provided with a safety hole 38 and a deformation groove 39, the far end of the deformation groove 39 is open and closed, the safety hole 38 and the deformation groove 39 are arranged at intervals, after the far end of the limiting pull rod 10 and the limiting block 34 are inserted in place, the safety protrusion 37 is clamped in the safety hole 38, and the deformation groove 39 is in an open state. The reset spring 33 is sleeved on the limiting pull rod 10, one end of the reset spring 33 is in butt joint with the inside of the first cylinder cavity 25, the other end of the reset spring 33 is in butt joint with the limiting block 34, and when the limiting pull rod 10 moves for a preset displacement relative to the limiting outer cylinder 9 and rotates for a certain angle relative to the limiting outer cylinder 9, the limiting clamping block 24 on the limiting pull rod 10 can be just clamped with the limiting outer cylinder 9, so that the limiting pull rod 10 is locked on the limiting outer cylinder 9. Moreover, because the spacing urceolus 9 is fixedly connected with the push tube 2, spacing pull rod 10 and action tube 3 fixed connection, spacing pull rod 10 is relative spacing urceolus 9 to remove the back of predetermineeing the displacement, action tube 3 is relative push tube 2 to remove the same displacement of predetermineeing, so in order to realize driving action tube 3 and remove relative push tube 2, in order to avoid leading to the rotation of bolt taking net 4 to turn round along with it in the rotatory joint in-process of spacing pull rod 10 moreover, this embodiment is with the distal end cover of bolt taking net 4 establish on action tube 3 all the time and can remove relative action tube 3, still allow the distal end of bolt taking net 4 to rotate relative action tube 3, the distal end of bolt taking net 4 can remove and can rotate relative action tube 3 promptly.
The thrombus removing net 4 comprises a first thrombus removing net 40 and a second thrombus removing net 41, wherein the first thrombus removing net 40 and the second thrombus removing net 41 are self-expanding nets and are provided with a plurality of meshes, so that the first thrombus removing net 40 and the second thrombus removing net 41 are in a radially contracted shrinkage state and a radially expanded expansion state, the first thrombus removing net 40 is a cutting bracket, for example, is formed by cutting a self-expanding tube by laser, compared with a woven bracket, the cutting bracket is harder, the shrinkage rate is low, namely, the deformation is small, the thrombus in a blood vessel is suitable for being cut to separate the thrombus from the blood vessel, the second thrombus removing net 41 is a woven bracket, for example, the woven bracket is softer, the shrinkage rate is high, namely, the deformation is large, the allowed meshes are smaller, the proximal end and the distal end of the first thrombus removing net 40 are both open ends, the proximal end of the second thrombus removing net 41 is an open end, the distal end of the second embolectomy 41 is fixedly connected with the sliding block 8 to form a furling end, the proximal end of the first embolectomy 40 is fixedly connected with the distal end of the pushing tube 2, the distal end of the first embolectomy 40 is fixedly connected with the proximal end of the second embolectomy 41 and the connecting part is in smooth transition connection, the second embolectomy 41 is used for collecting separated thrombus, when the first embolectomy 40 and the second embolectomy 41 are retracted, thrombus in a blood vessel enters the second embolectomy 41 from the proximal opening of the first embolectomy 40 to be collected, the length of the second embolectomy 41 is 4 times, 5 times, 6 times, 7 times or 8 times of the length of the first embolectomy 40, as long as the ratio of the length of the second embolectomy 41 to the length of the first embolectomy 40 is 3-8, the second embolectomy 41 can capture enough thrombus, and the second embolectomy 41 is particularly suitable for deep vein embolectomy, the reason is that the deep vein thrombus is larger and generally found to be later and thus harder, the thrombus in the blood vessel is separated just first by using the shorter first thrombus-taking mesh 40, and then the separated thrombus is collected by using the longer second thrombus-taking mesh 41 to capture the thrombus.
The first action block 6 is located in the second thrombolytic net 41, the second action block 7 is located outside the second thrombolytic net 41, and since the slide block 8 is fixed at the distal end of the second thrombolytic net 41, when the action tube 3 moves in the proximal direction along the distal end and generates relative displacement with the push tube 2, the action tube 3 directly acts on the distal end of the second thrombolytic net 41 through the second action block 7 and the slide block 8 to move in the proximal direction, so that the second thrombolytic net 41 is directly shortened to expand in the radial direction, and the first thrombolytic net 40 connected with the second thrombolytic net 41 is driven by the second thrombolytic net 41 to indirectly shorten to expand in the radial direction, then the action tube 3 does not directly shorten the first thrombolytic net 40 to expand in the radial direction, if the second thrombolytic net 41 is longer, the first thrombolytic net 40 cannot be completely expanded, i.e. the expansion is not ideal, so that the thrombus is cut by the first thrombolytic net 40 is influenced, and an action structure is arranged between the action tube 3 and the first thrombolytic net 40, so that the action structure is configured to directly expand the second thrombolytic net 40 in the radial direction along the second end through the action tube 7, so that the first thrombolytic net 40 is directly expanded in the radial direction, and the second thrombolytic net 41 is directly shortened to expand in the radial direction. The action structure comprises a first action end 42 fixed on the action tube 3 and a second action end 43 fixed on the inner wall of the first thrombus taking net 40, wherein the first action end 42 is an action protrusion protruding out of the outer surface of the action tube 3, the second action end 43 is an action ring protruding towards the inside of the first thrombus taking net 40 and sleeved on the action tube 3, and the maximum radial dimension of the action ring is smaller than the maximum radial dimension of the action protrusion, so that the action tube 3 directly drives the first thrombus taking net 40 to be shortened by abutting the first action end 42 against the second action end 43 so as to be expanded in the radial direction.
In actual thrombus taking, referring to fig. 15, firstly, the thrombus taking tube 1 containing the first thrombus taking net 40 and the second thrombus taking net 41 is conveyed into the blood vessel 100, and the thrombus taking tube 1 penetrates through the distal end of thrombus 200 in the blood vessel 100 by pushing the guide wire and the conical end of the distal end of the second action block 7 in the process; then, the thrombus removing tube 1 is pulled along the direction from the far end to the near end, namely the thrombus removing tube 1 is withdrawn, so that the first thrombus removing net 40 and the second thrombus removing net 41 are in a release state, at this time, the first thrombus removing net 40 and the second thrombus removing net 41 are still in a contracted state as shown in fig. 16 because the first action block 6 is abutted against or close to the far end of the second thrombus removing net 41, and the near end of the first thrombus removing net 40 is positioned at the far end side of thrombus 200; then, the limiting pull rod 10 is pulled along the direction from the far end to the near end, the limiting pull rod 10 moves by preset displacement relative to the limiting outer cylinder 9, at the moment, the acting tube 3 moves by the same preset displacement relative to the pushing tube 2 along the direction from the far end to the near end, so that the acting tube 3 directly acts on the far end of the second bolt taking net 41 through the second acting block 7 and the sliding block 8 to move towards the near end, the second bolt taking net 41 is further directly shortened to be expanded in the radial direction, the second bolt taking net 41 drives the first bolt taking net 40 connected with the second bolt taking net 41 to be indirectly shortened to be expanded in the radial direction, meanwhile, the acting tube 3 also directly drives the first bolt taking net 40 to be shortened to be expanded in the radial direction through the abutting of the first acting end 42, and rotates the limiting pull rod 10 to lock the limiting pull rod 10 and the limiting outer cylinder 9, and the first bolt taking net 40 and the second bolt taking net 41 finally realize an expanded state as shown in fig. 17; then, the limiting outer cylinder 9 or the thrombus taking tube 1 is pulled along the direction from the far end to the near end so that the first thrombus taking net 40 and the second thrombus taking net 41 move relative to the blood vessel 100, in the process, the thrombus 200 in the blood vessel 100 is cut by the first thrombus taking net 40 so that the thrombus 200 is separated from the blood vessel 100, the separated thrombus 200 is collected by the second thrombus taking net 41, namely, the thrombus 200 in the blood vessel 100 enters the second thrombus taking net 41 from the near end opening of the first thrombus taking net 40 to be collected, and finally, the thrombus 200 is positioned in the first thrombus taking net 40 and the second thrombus taking net 41 as shown in fig. 18; finally, the spacing outer cylinder 9 or the thrombus removing tube 1 is pulled along the direction from the far end to the near end, so that the first thrombus removing net 40 and the second thrombus removing net 41 move into the sheath tube relative to the blood vessel 100 to withdraw the blood vessel 100, in order to facilitate the first thrombus removing net 40 and the second thrombus removing net 41 with thrombus 200 to be smoothly withdrawn into the sheath tube, after the near end of the first thrombus removing net 40 just enters the sheath tube, the spacing pull rod 10 is unlocked with the spacing outer cylinder 9 by rotating the spacing pull rod 10, the spacing pull rod 10 is pushed along the direction from the near end to the far end, so that the spacing pull rod 10 moves for preset displacement relative to the spacing outer cylinder 9, then the position between the spacing pull rod 10 and the spacing outer cylinder 9 is relatively fixed due to the action of the reset spring 33, at the moment, the action tube 3 moves for the same preset displacement relative to the pushing tube 2 along the direction from the near end to the far end, in this way, the action tube 3 directly acts on the distal end of the second embolectomy 41 through the first action block 6 and the sliding block 8 to move towards the distal end direction, so that the second embolectomy 41 is directly stretched to shrink in the radial direction, and the first embolectomy 40 connected with the second embolectomy 41 is indirectly stretched to shrink in the radial direction, as shown in fig. 19, before the first embolectomy 40 and the second embolectomy 41 are completely retracted into the sheath, the first embolectomy 40 and the second embolectomy 41 are configured to have at least a stage of being in a whole contracted state, so that the first embolectomy 40 and the second embolectomy 41 with thrombus 200 can be completely retracted into the sheath after being in the whole radial contracted state, and the thrombus 200 is prevented from being extruded and escaping due to scratch between the first embolectomy 40, the second embolectomy 41 and the inner wall of the sheath.
Moreover, since the distal end of the second embolectomy 41, that is, the slider 8, is sleeved on the acting tube 3 and can slide within the range of the spacing defined between the first acting block 6 and the second acting block 7, the distal end of the second embolectomy 41 is not completely limited, and thus, after the first embolectomy 40 and the second embolectomy 41 are contracted, the distal end of the second embolectomy 41 can also move towards the second acting block 7 relative to the acting tube 3 to further contract, so that the phenomenon that the second embolectomy 41 cannot smoothly withdraw into the sheath 300 due to "bulge" as shown in fig. 20 can be avoided. At the same time, after the first and second embolectomy 40, 41 have been expanded, the distal end of the second embolectomy 41 can also be moved relative to the working tube 3 toward the first working block 6 for further expansion. Therefore, the arrangement is such that the conditions such as thrombus volume and the like in the first thrombus removing net 40 and the second thrombus removing net 41 can be dynamically adjusted along with the conditions such as thrombus volume and the like in the first thrombus removing net 40 and the second thrombus removing net 41, so that the thrombus 200 can be uniformly distributed in the first thrombus removing net 40 and the second thrombus removing net 41 in an automatic adjusting manner, and the thrombus removing effect is better.
It will be appreciated that although the invention has been described above in terms of preferred embodiments, the above embodiments are not intended to limit the invention. Many possible variations and modifications of the disclosed technology can be made by anyone skilled in the art without departing from the scope of the technology, or the technology can be modified to be equivalent. Therefore, any simple modification, equivalent variation and modification of the above embodiments according to the technical substance of the present invention still fall within the scope of the technical solution of the present invention.

Claims (10)

1. A thrombus taking device with controllable thrombus taking net shrinkage and expansion, comprising a thrombus taking net (4), a pushing tube (2) and a thrombus taking tube (1), wherein the thrombus taking tube (1) is provided with a tube cavity (5) for accommodating the thrombus taking net (4) and the pushing tube (2), the thrombus taking net (4) is provided with a shrinkage state with radial shrinkage and an expansion state with radial expansion, and the proximal end of the thrombus taking net (4) is fixedly connected with the distal end of the pushing tube (2), the thrombus taking device is characterized by further comprising an acting tube (3) provided with a first acting block (6) and a second acting block (7), the first acting block (6) and the second acting block (7) are both fixed on the acting tube (3) and are arranged at intervals, the distal end of the thrombus taking net (4) is sleeved on the acting tube (3) and can slide in a spacing range defined between the first acting block (6) and the second acting block (7), and the acting tube (3) is configured to move along a preset direction and relatively move along the radial direction through the first acting block (6) or the second acting block (7) when the first acting block (6) is driven to move relatively to the pushing tube (2) and move radially through the first acting block (4) and the second acting block (7) to the thrombus taking net (4); the thrombus taking net (4) comprises a first thrombus taking net (40) and a second thrombus taking net (41), an action structure is arranged between the action tube (3) and the first thrombus taking net (40), and the action structure is configured to drive the first thrombus taking net (40) to be shortened to be expanded in the radial direction when the action tube (3) drives the distal end of the second thrombus taking net (41) to slide towards the proximal direction through a second action block (7) so that the second thrombus taking net (41) expands in the radial direction.
2. The thrombolytic device according to claim 1, wherein the proximal end of the thrombolytic net (4) is an open end, the distal end of the thrombolytic net (4) is fixedly connected with a slider (8) and is convergent to the slider (8) to form a convergent end, the slider (8) is sleeved on the action tube (3) and is configured to be slidable within a range of spacing defined between the first action block (6) and the second action block (7).
3. The thrombus removal device according to claim 2, wherein the first action block (6) is located in the thrombus removal net (4), and when the action tube (3) is pushed in the proximal and distal directions and is displaced relative to the push tube (2), the first action block (6) can drive the sliding block (8) to slide in the distal directions so that the thrombus removal net (4) is extended to be contracted in the radial direction.
4. The thrombus removal device according to claim 2, wherein the second action block (7) is located outside the thrombus removal net (4), and when the action tube (3) is pulled in the distal direction and the pushing tube (2) is displaced relatively, the second action block (7) drives the sliding block (8) to slide in the proximal direction so that the thrombus removal net (4) is shortened to expand radially.
5. The thrombus taking device according to claim 1, wherein the action tube (3) and the pushing tube (2) are coaxially arranged, the action tube (3) is at least partially positioned in the pushing tube (2), the proximal end of the pushing tube (2) is fixedly connected with a limiting outer cylinder (9), and the proximal end of the action tube (3) is fixedly connected with a limiting pull rod (10).
6. The thrombus taking device according to claim 5, wherein the limit pull rod (10) is fixedly connected with the limit outer cylinder (9) in a sliding clamping manner; or the limiting pull rod (10) is rotationally clamped and fixed with the limiting outer cylinder (9), and the acting pipe (3) can also rotate relative to the distal end of the thrombus taking net (4).
7. The thrombus taking device according to claim 6, wherein the limit outer cylinder (9) comprises a first half cylinder body (11), a second half cylinder body (12), a first cylinder seat (13) and a second cylinder seat (14), the first half cylinder body (11) and the second half cylinder body (12) are mutually butted to form a cylinder body, the first cylinder seat (13) and the second cylinder seat (14) are respectively fixed at the proximal end and the distal end of the cylinder body, a first cylinder cavity (25) is arranged in the first cylinder seat (13), a second cylinder cavity (26) is arranged in the second cylinder seat (14), the limit pull rod (10) is in sliding and rotating connection with the first cylinder cavity (25) and the second cylinder cavity (26), a limit inner cylinder (19) with a limit clamping groove (23) is fixedly connected in the cylinder body, and a limit clamping block (24) clamped with the limit clamping groove (23) is arranged on the limit pull rod (10).
8. The thrombus removal device according to claim 7, wherein the proximal end of the first half cylinder (11) and the proximal end of the second half cylinder (12) are each provided with a proximal clamping groove (15), the first cylinder seat (13) is provided with two proximal clamping blocks (16) clamped with the proximal clamping grooves (15), the two proximal clamping blocks (16) are configured to be symmetrically arranged with respect to the abutting surface of the first half cylinder (11) and the second half cylinder (12) abutting each other, and/or the distal end of the first half cylinder (11) and the distal end of the second half cylinder (12) are each provided with a distal clamping groove (17) opposite to each other, the second cylinder seat (14) is provided with two distal clamping blocks (18) clamped with the distal clamping grooves (17), and the two distal clamping blocks (18) are configured to be symmetrically arranged with respect to the abutting surface of the first half cylinder (11) and the second half cylinder (12) abutting each other.
9. The thrombus taking device according to claim 7, wherein the pushing tube (2) is fixedly connected with the second cylinder seat (14) and is communicated with the second cylinder cavity (26), the acting tube (3) is sleeved with a first sealing ring (31) for sealing between the second cylinder cavity (26) and the inside of the cylinder body, and a first injection pipeline (28) communicated with the second cylinder cavity (26) is arranged outside the second cylinder seat (14).
10. The thrombus taking device according to claim 7, wherein the proximal end of the thrombus taking tube (1) is fixed with a thrombus taking tube seat (29), the pushing tube (2) is sleeved with a second sealing ring (32) for sealing between the inside and the outside of the thrombus taking tube seat (29), and the outside of the thrombus taking tube seat (29) is provided with a second injection pipeline (30) communicated with the tube cavity (5).
CN202310139023.XA 2022-12-06 2023-02-08 Thrombolysis device with controllable retraction and expansion of thrombolysis net Active CN115844491B (en)

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