CN1158111C - Hot perfusion chemotherapeutic apparatus - Google Patents
Hot perfusion chemotherapeutic apparatus Download PDFInfo
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- CN1158111C CN1158111C CNB021136300A CN02113630A CN1158111C CN 1158111 C CN1158111 C CN 1158111C CN B021136300 A CNB021136300 A CN B021136300A CN 02113630 A CN02113630 A CN 02113630A CN 1158111 C CN1158111 C CN 1158111C
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- heat
- pipe
- perfusion
- medicinal liquid
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Abstract
The present invention discloses a heat perfusion chemotherapeutic device for treating malignant tumor in the peritoneal cavity, which comprises a casing, a liquid storing container, a liquid medicine conveying pipe, a heat exchange device, an insulating device and an adjustable extrusion perfusion pump, wherein the insulating device comprises an outer sleeve pipe arranged on the liquid medicine conveying pipe of the external output end of the casing, and an insulating jacket positioned in the clearance between two pipes; the liquid storing container is provided with a circulating liquid medicine reflow inlet and a filter screen. The present invention can realize the closed cycle of perfusion liquid medicine between the peritoneal cavity and the device, the lost heat quantity in perfusion can be replenished continuously, and the temperature of the perfusion liquid medicine can be accurately controlled at the therapy temperature of 42 to 43 DEG C. A perfusion pipe is placed in an operation, heat perfusion can be implemented many times after the operation so as to ensure therapy times and therapy time every time, and the therapeutic effect is more ideal.
Description
Affiliated technical field
The present invention relates to a kind of intraperitoneal hot perfusion chemotherapeutic apparatus.
Background technology
The intraperitoneal hot perfusion chemotherapeutic is the new technique of the various malignant tumor of treatment intraperitoneal, and it can be killed and remain in Intraabdominal cancerous cell and little focus in the operation, shifts and recurrence for prevention and treatment gastrointestinal tract cancer postoperative peritoneum, and significant curative effect is arranged.At present, domestic still do not have can temperature control can guarantee again that effective equipment of treatment time implements this Therapeutic Method, China national Department of Intellectual Property discloses a kind of anticancer machine of perfusion of heating with notification number 2211286, solved the problem that medicinal liquid is heated and poured into driving, but there is following shortcoming in it: one, and the medicinal liquid consumption is big; Its two, the temperature control weak effect; Its three, can not under the condition that does not reduce the perfusion solution temperature, guarantee enough infusion times.
The technology of the present invention content
The objective of the invention is to overcome above-mentioned the deficiencies in the prior art and a kind of hot perfusion chemotherapeutic apparatus is provided, it can realize perfusion solution closed circulation between human abdominal cavity and device, the heat that loses in the perfusion can constantly obtain to replenish, and the temperature of perfusion solution can accurately be controlled at required treatment temperature (42～43 ℃).
The present invention adopts following technical scheme: it comprises casing, storage liquid container, medicinal liquid carrier pipe, heat-exchange device, adjustable extruding charge pump; Described storage liquid container bottom is provided with the outflow interface, the top is provided with lid; Described adjustable extruding filling main pump is serially connected with on the medicinal liquid carrier pipe of setting up heat-exchange device and with the storage liquid container and is connected; Described heat-exchange device comprises heat exchange tank, heat-exchange tube, heater and pump, heater is provided with water inlet pipe and the outlet pipe that constitutes water-flow circuit with the heat exchange tank jointly, pump is serially connected with on the outlet pipe, and heat-exchange tube coiling dipping bath is in the heat exchange tank; Described storage liquid container is provided with circulation medicinal liquid reflux inlet and drainage screen; Described medicinal liquid carrier pipe is provided with attemperator, comprise the medicinal liquid exterior coating of pipe line pipe of being located at the outer outfan of casing and the insulation water jacket that is positioned at two ligaments, described trocar sheath two ends are provided with insulation water inlet and outlet, described inlet divides support interface to be connected by a set trident of the pipeline and the outlet pipe of heater, and described outlet is connected with the heat exchange tank with pipeline.
As improvement of the present invention, described drainage screen aperture is 40～75 microns.
As a further improvement on the present invention, the medicinal liquid carrier pipe proximal end of the outer outfan of casing is provided with the temperature pressure sensing probe.
The present invention has following advantage:
One, owing to infusion liquid closed circulation between abdominal cavity and heat-exchange device, the heat that loses in the perfusion can constantly obtain to replenish, and the temperature of perfusion solution can accurately be controlled at required treatment temperature (42～43 ℃);
Two, can under the situation that does not reduce the infusion liquid temperature, guarantee enough infusion times (60～120 minutes);
Three, infusion liquid recycles, and does not increase its use amount because of infusion time prolongs, and has saved medical expense;
Four, infusion liquid recycles, and can guarantee the enough medicinal liquid amounts of pouring into of intraperitoneal (2500～3000 milliliters), avoids intraperitoneal to have heat perfusion " dead space ", thereby can obtain ideal curative effect;
Five, the perfusion solution of closed circulation is difficult for contaminatedly, is difficult for causing the abdominal cavity secondary infection, and in addition, the medicinal liquid carrier pipe (containing heat-exchange tube) of setting up attemperator can be made into disposable special product, can cross infection between the different patients;
Six, by placing the intraperitoneal perfusion pipeline in the art, postoperative can repeatedly be implemented hyperthermic perfusion chemotherapy to the abdominal cavity, and curative effect is better;
Seven, this device also has characteristics such as safe and reliable, that precision is high, automaticity is high, and is easy and simple to handle.
The present invention is described in further detail below in conjunction with embodiment.
Marginal data
Fig. 1 is the operation principle sketch map of an embodiment of the present invention.
The specific embodiment
As shown in Figure 1, the present invention includes casing, storage liquid container 2, medicinal liquid carrier pipe 3, heat-exchange device 4, adjustable extruding charge pump 6; Described storage liquid container 2 bottoms are provided with outflow interface 7, the top is provided with lid 1 and is convenient to add at any time medicinal liquid; Described adjustable extruding charge pump 6 is serially connected with on the medicinal liquid carrier pipe 3 of setting up heat-exchange device 4 and with storage liquid container 2 and is connected, and adjustable extruding charge pump 6 provides circumfusion power to make perfusion solution form circulation between abdominal cavity and hot perfusion chemotherapeutic apparatus; Described heat-exchange device 4 comprises heat exchange tank 8, heat-exchange tube 9, heater 15 and pump 16, heater 15 is provided with and heat exchange tank 8 common water inlet pipe 17 and the outlet pipes 18 that constitute water-flow circuit, pump 16 is serially connected with on the outlet pipe 18, heat-exchange tube 9 coiling dipping baths are in heat exchange tank 8, when the perfusion solution of room temperature passes through heat-exchange device 4, temperature is risen to 45 ℃ by indirect, under the effect that can debug extruding charge pump 6, flow with 600～800 ml/min injects the abdominal cavity, after the abdominal cavity was poured medicinal liquid and is full of, perfusion solution flowed out abdominal cavity through another drainage tube of intraperitoneal and enters storage liquid container 2; Described storage liquid container 2 is provided with circulation medicinal liquid reflux inlet 10 and drainage screen 11, and drainage screen 11 apertures are good with 40～75 microns, and its effect is to remove clot in the continuous circulation perfusion solution, fragment of tissue etc.; Described medicinal liquid carrier pipe 3 is provided with attemperator 5, the trocar sheath that comprises the medicinal liquid carrier pipe 3 of being located at the outer outfan of casing, with the insulation water jacket that is positioned at two ligaments, described trocar sheath two ends are provided with the inlet 12 and the outlet 13 of insulation water, described inlet 12 divides support interface 19 to be connected by outlet pipe 18 set tridents of pipeline and heater 15, described outlet 13 is connected with heat exchange tank 8 with pipeline, pump 16 continuous outputs are heated to 45 ℃ insulation water by heater 15, part insulation water is gone into attemperator 5 by a branch road of outlet pipe 18 from 12 retroperfusions that enter the mouth, another part enters heat exchange tank 8, like this, the perfusion solution temperature in injection abdominal cavity can remain at the treatment temperature of setting.
A kind of being improved to of the present invention, medicinal liquid carrier pipe 3 proximal ends of outfan are provided with temperature pressure sensing probe 14 outside casing, with the temperature and the intraabdominal pressure of monitoring Intraabdominal infusion liquid, guarantee perfusion safety.Another kind of the present invention is improved on adjustable extruding charge pump 6 and sets up electronic flow and rotating speed display device, is convenient to regulate flow and rotating speed.Further improvement of the present invention is that the internal diameter of heat-exchange tube 3 is made as 4 millimeters, and pipe thickness is 1 millimeter.
Claims (5)
1, a kind of hot perfusion chemotherapeutic apparatus, comprise: casing, the storage liquid container, the medicinal liquid carrier pipe, heat-exchange device, adjustable extruding charge pump, described storage liquid container bottom is provided with the outflow interface, the top is provided with lid, described adjustable extruding charge pump is serially connected with on the medicinal liquid carrier pipe of setting up heat-exchange device, and with the storage liquid container be connected, described heat-exchange device comprises the heat exchange tank, heat-exchange tube, heater, pump, heater is provided with water inlet pipe and the outlet pipe that constitutes water-flow circuit with the heat exchange tank jointly, pump is serially connected with on the outlet pipe, heat-exchange tube coiling dipping bath is in the heat exchange tank, it is characterized in that: described storage liquid container is provided with circulation medicinal liquid reflux inlet and drainage screen, described medicinal liquid carrier pipe is provided with insulation setting, comprise the medicinal liquid exterior coating of pipe line pipe of being located at the outer outfan of casing, with the insulation water jacket that is positioned at two ligaments, described trocar sheath two ends are provided with insulation water inlet and outlet, described inlet divides support interface to be connected by a set trident of a pipeline and the outlet pipe of heater, and described outlet is connected with the heat exchange tank with pipeline.
2, hot perfusion chemotherapeutic apparatus according to claim 1 is characterized in that: described drainage screen aperture is 40～75 microns.
3, hot perfusion chemotherapeutic apparatus according to claim 2 is characterized in that: described heat-exchange tube internal diameter is 4 millimeters, 1 millimeter of thickness of pipe wall.
4, hot perfusion chemotherapeutic apparatus according to claim 3 is characterized in that: the temperature pressure sensing probe that also comprises the medicinal liquid carrier pipe proximal end place that is located at the outer outfan of casing.
5, hot perfusion chemotherapeutic apparatus according to claim 4 is characterized in that: also comprise electronic flow and the rotating speed display device be located on the adjustable extruding charge pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021136300A CN1158111C (en) | 2002-04-17 | 2002-04-17 | Hot perfusion chemotherapeutic apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021136300A CN1158111C (en) | 2002-04-17 | 2002-04-17 | Hot perfusion chemotherapeutic apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1374138A CN1374138A (en) | 2002-10-16 |
| CN1158111C true CN1158111C (en) | 2004-07-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021136300A Expired - Fee Related CN1158111C (en) | 2002-04-17 | 2002-04-17 | Hot perfusion chemotherapeutic apparatus |
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| Country | Link |
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| CN (1) | CN1158111C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101103937B (en) * | 2006-07-10 | 2012-03-21 | 广州保瑞医疗技术有限公司 | External circulation heat perfusion therapeutic instrument |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201798846U (en) * | 2010-09-26 | 2011-04-20 | 西安好博士医疗科技有限公司 | Coelom circulation thermal-chemotherapy perfusion system |
| CN102406969A (en) * | 2010-09-26 | 2012-04-11 | 西安好博士医疗科技有限公司 | Dual-row and dual-layer perfusion pipeline device |
| CN107185104A (en) * | 2017-06-16 | 2017-09-22 | 刘晓 | A kind of multi-functional chemotherapy control device of Internal Medicine-Oncology |
| CN108553744A (en) * | 2018-01-10 | 2018-09-21 | 张冬平 | A kind of multi-functional chemotherapy control device of Internal Medicine-Oncology |
| CN109908465A (en) * | 2019-04-28 | 2019-06-21 | 李政伟 | A kind of multi-functional chemotherapy control device of Internal Medicine-Oncology |
| CN110237412A (en) * | 2019-07-22 | 2019-09-17 | 上海市第一人民医院 | On Irrigation of Bladder Chemotherapy instrument |
| CN111419527B (en) * | 2020-04-10 | 2022-03-08 | 刘扬帆 | Abdominal cavity hot perfusion chemotherapy device |
| CN113893112A (en) * | 2021-09-23 | 2022-01-07 | 海南医学院第一附属医院 | Multifunctional chemotherapy control device for medical oncology |
| CN115530157B (en) * | 2022-11-03 | 2023-04-14 | 河南中医药大学第一附属医院 | Isolated myocardial tissue perfusion device |
| CN115777688B (en) * | 2022-11-03 | 2023-05-12 | 河南中医药大学第一附属医院 | Isolated myocardial tissue perfusion experiment system |
-
2002
- 2002-04-17 CN CNB021136300A patent/CN1158111C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101103937B (en) * | 2006-07-10 | 2012-03-21 | 广州保瑞医疗技术有限公司 | External circulation heat perfusion therapeutic instrument |
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| Publication number | Publication date |
|---|---|
| CN1374138A (en) | 2002-10-16 |
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