CN115807766A - Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system - Google Patents

Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system Download PDF

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Publication number
CN115807766A
CN115807766A CN202211613753.0A CN202211613753A CN115807766A CN 115807766 A CN115807766 A CN 115807766A CN 202211613753 A CN202211613753 A CN 202211613753A CN 115807766 A CN115807766 A CN 115807766A
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China
Prior art keywords
plunger
proximal end
pump
housing
blood pump
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CN202211613753.0A
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范渊杰
杨迁红
黄霖
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Shanghai Xinhengrui Medical Technology Co ltd
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Shanghai Xinhengrui Medical Technology Co ltd
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Priority to CN202211613753.0A priority Critical patent/CN115807766A/en
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Abstract

The invention provides a plunger pump zero calibration method, blood pump perfusion cleaning equipment and a blood pump system. The zero calibration method comprises the following steps: controlling a plunger of the plunger pump to move towards the near end of the plunger pump, sensing the position of the near end face of the plunger relative to the near end of the housing, stopping the plunger to move if the position of the near end face of the plunger meets a preset condition, and determining the position of the near end face of the plunger at the moment as a near end limit position; controlling the plunger to move to a preset position towards the far end of the plunger pump according to the near end limit position; and after the preset position is reached, the plunger stops moving, and the position of the distal end surface or the proximal end surface of the plunger at the moment is determined as the plunger zero position. When the blood pump perfusion cleaning equipment is started for the first time or the perfusion cleaning equipment is started again after the abnormal release of the control host, the zero position of the plunger is calibrated again by the zero position calibration method, so that the reciprocating movement distance of the plunger pump is accurately controlled, the risk of collision between the near-end surface of the plunger and the near-end of the housing is reduced, and the risk of abrasion of the far-end surface of the plunger is reduced.

Description

Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system
Technical Field
The invention relates to the technical field of medical instruments, in particular to a plunger pump zero calibration method, blood pump perfusion cleaning equipment and a blood pump system.
Background
Heart failure patients die worldwide each year because the amount of heart pumped blood cannot maintain the blood supply required for normal metabolism of body tissues. At present, the heart failure is treated in a common way by the following steps: medication, heart transplantation, ventricular assist device therapy, and the like. In severe heart failure patients, the therapeutic effect of drug therapy is quite limited, most of the patients need to be treated by using heart transplantation and ventricular assist devices, but the sources of heart transplantation are limited, so that the artificial ventricular assist devices become the main choices of patients and doctors.
When the blood pump is used as one of the artificial ventricle auxiliary devices, abrasive dust can be generated by the relative motion between a flexible shaft and a rotating shaft sleeve in a rotating shaft component of the blood pump and between a rigid impeller rotating shaft and a support piece (such as a bearing), and if abrasive dust particles enter a human body, thrombus can be formed and the life and health of the human body are damaged. Moreover, because the rotating shaft assembly is positioned in a human body, blood entering the rotating shaft assembly can be condensed on a structural part of the rotating shaft assembly to form thrombus, so that the load of the rotating shaft assembly is increased, and the problems of transmission failure and the like are caused. Therefore, the perfusion cleaning device is needed to be adopted to perfuse and clean the rotating shaft assembly, so that abrasive dust is prevented from entering a human body, and thrombus is prevented from being formed.
The existing perfusion cleaning device comprises a plunger pump arranged in a housing, and heparin or glucose purification liquid is released to a blood pump by the plunger pump. In the clinical use process, the plunger of the plunger pump is driven by the motor to do reciprocating linear motion, and liquid suction and liquid discharge are realized through the reciprocating linear motion of the plunger. The position of the plunger is very important, generally, the plunger in the housing reaches a zero position when the plunger pump is delivered from a factory, so when the plunger pump is started to fill and clean the blood pump, the reciprocating movement distance of the plunger is determined according to the zero position on the premise that the plunger reaches the zero position. However, the plunger pump is not considered to move after leaving the factory, or the control host is abnormally shut down, the plunger pump is suddenly stopped in the operation process, the control host cannot timely store the end face position of the plunger pump, the problems can cause the plunger to be not at the zero position, at the moment, the plunger pump is wrapped by the housing, and an operator cannot know the distance between the near end face of the plunger and the near end of the housing. If the position of the proximal end face of the plunger is not clear, the distance of the plunger moving towards the distal end cannot be accurately controlled, so that the deviation of the infusion flow of the infusion flushing liquid and the infusion amount of the heparin solution can be caused slightly, the possibility of thrombosis is increased, and the damage of the infusion flushing system can be caused seriously, such as the tooth breaking and the tooth breaking of a gear-rack mechanism, or the plunger moves out of the end face, so that the plunger is damaged, and finally the function failure of the infusion system is caused.
Disclosure of Invention
Therefore, an object of the present invention is to provide a method for calibrating a plunger pump zero position, a blood pump perfusion cleaning device, and a blood pump system, which can recalibrate the plunger zero position when the blood pump perfusion cleaning device is first started or the perfusion cleaning device is restarted after the control host is abnormally removed, and can normally start the plunger pump to realize perfusion cleaning of the blood pump only after the plunger reaches the calibrated zero position.
In order to achieve the above object, the present invention provides a plunger pump zero position calibration method for perfusion cleaning of a blood pump, wherein the plunger pump is arranged in a housing, and the plunger pump zero position calibration method comprises:
controlling a plunger of the plunger pump to move towards a proximal end of the plunger pump;
in the process that the plunger moves towards the near end, the position of the near end face of the plunger relative to the near end of the housing is sensed, if the position of the near end face of the plunger meets a preset condition, the plunger is controlled to stop moving, and the position of the near end face of the plunger at the moment is determined as a near end limit position;
controlling the plunger to move to a preset position towards the distal end of the plunger pump according to the proximal end limit position;
and after the preset position is reached, controlling the plunger to stop moving, and determining the position of the distal end surface of the plunger at the moment as the plunger zero position or determining the position of the proximal end surface of the plunger at the moment as the plunger zero position.
Optionally, the plunger pump zero calibration method further includes:
the plunger is controlled by a motor to move towards the proximal end, a trigger signal is generated when the position of the proximal end face of the plunger meets a preset condition, the motor is made to stop running in response to the trigger signal, and then the plunger stops moving;
the motor controls the plunger to move towards the far end, and after the plunger reaches the preset position, the motor stops operating, so that the plunger stops moving.
Optionally, the preset condition is that the plunger proximal end face touches or is about to touch the housing proximal end.
Optionally, the plunger pump zero calibration method further includes:
determining the preset position according to the near-end limit position and the stroke of the plunger moving towards the far end, and acquiring the target number of turns of the motor;
and in the process that the plunger moves towards the far end, if the actual number of turns of the motor reaches the target number of turns of the motor, the motor stops running.
Optionally, the position of the plunger proximal end surface relative to the housing proximal end is sensed by an in-place sensor, and when the position of the plunger proximal end surface meets the preset condition that the plunger proximal end surface touches the housing proximal end, the in-place sensor is triggered and generates the trigger signal according to an event that the in-place sensor is triggered, wherein the in-place sensor is disposed on one of the housing proximal end and the plunger proximal end surface.
Optionally, a distance sensor is used to sense a distance between the plunger proximal end surface and the housing proximal end, and determine a position of the plunger proximal end surface relative to the housing proximal end according to the distance, and the trigger signal is generated when the distance between the plunger proximal end surface and the housing proximal end surface meets the preset condition that the plunger proximal end surface touches or is about to touch the housing proximal end, wherein the distance sensor is disposed on one of the housing proximal end and the plunger proximal end surface.
Optionally, a force sensor senses a stress state of the casing proximal end and/or the plunger pump, a position of the plunger proximal end surface relative to the casing proximal end is determined according to the stress state, and the trigger signal is generated when a stress value corresponding to the stress state meets the preset condition that the plunger proximal end surface touches the casing proximal end, wherein the force sensor is disposed on at least one of the casing proximal end and a base of the plunger pump, and the base supports a motor transmission rod.
Optionally, an output torque of the motor is sensed by a torque sensor, a position of the plunger proximal end surface relative to the casing proximal end is determined according to the output torque, and the trigger signal is generated when the output torque meets the preset condition that the plunger proximal end surface touches the casing proximal end, wherein the torque sensor is arranged on a motor transmission rod of the plunger pump.
Optionally, during a proximal movement of the plunger, an output electrical signal of the motor is sensed, a position of a proximal end face of the plunger relative to the proximal end of the housing is determined according to the output electrical signal, and the trigger signal is generated when the output electrical signal meets the preset condition that the proximal end face of the plunger touches the proximal end of the housing.
Optionally, the motor is controlled by a control host to drive the plunger to move towards the proximal end or the distal end, and the control host is further configured to send the trigger signal to the motor, so that the motor stops running in response to the trigger signal.
Optionally, the plunger pump zero calibration method is executed when the blood pump perfusion cleaning device is started for the first time or when the blood pump perfusion cleaning device is started again after the control host is abnormally relieved.
In order to achieve the above purpose, the present invention further provides a blood pump perfusion cleaning device, which comprises a housing, a plunger pump, a sensor and a control host, wherein the plunger pump is arranged in the housing; the control host is arranged outside the housing; at least one of the housing and the plunger pump is provided with the sensor; the sensor is used for sensing the position of the plunger proximal end face relative to the housing proximal end during the proximal movement of the plunger; the control host is used for executing any plunger pump zero calibration method for perfusion cleaning of the blood pump.
Optionally, the blood pump perfusion cleaning device further comprises a motor in communication connection with the control host; the motor is connected with a motor transmission interface of the plunger pump; the control host is used for controlling the motor to drive the plunger to move towards the near end or the far end, and is also used for sending a trigger signal to the motor, so that the motor stops running in response to the trigger signal.
In order to achieve the above object, the present invention further provides a blood pump system, which includes a blood pump assembly, a delivery conduit, a hub, a flushing pipeline, and any one of the perfusion cleaning devices for the blood pump; the blood pump assembly is disposed at the distal end of the delivery catheter; the flushing pipeline penetrates through the junction box, extends along the conveying conduit and is connected with the proximal end of the blood pump assembly; the plunger pump of the blood pump perfusion cleaning equipment is arranged on the flushing pipeline and used for pushing the purified liquid to the blood pump assembly through the flushing pipeline.
The invention provides a plunger pump zero calibration method for perfusion cleaning of a blood pump, which comprises the following steps of; controlling a plunger of the plunger pump to move towards a proximal end of the plunger pump; in the process that the plunger moves towards the near end, the position of the near end face of the plunger relative to the near end of the housing is sensed, if the position of the near end face of the plunger meets a preset condition, the plunger is controlled to stop moving, and the position of the near end face of the plunger at the moment is determined as a near end limit position; controlling the plunger to move to a preset position towards the distal end of the plunger pump according to the proximal end limit position; and after the preset position is reached, controlling the plunger to stop moving, and determining the position of the distal end surface of the plunger at the moment as the plunger zero position or determining the position of the proximal end surface of the plunger at the moment as the plunger zero position.
Therefore, when the perfusion cleaning equipment is started for the first time or the perfusion cleaning equipment is started again after the abnormity of the control host is relieved, the plunger zero position is calibrated again according to the plunger pump zero position calibration method, and the plunger pump can be started to perfuse and clean the blood pump only after the plunger reaches the calibrated zero position, so that the reciprocating distance of the plunger pump is accurately controlled; specifically, after the proximal extreme position is known, the distance of the plunger pump moving to the proximal end can be accurately controlled, and the proximal end face of the plunger is prevented from colliding with the proximal end of the housing; given the plunger zero position, the distance that the plunger pump moves distally can be precisely controlled, reducing the risk of wear on the distal face of the plunger.
The blood pump perfusion cleaning equipment and the blood pump system provided by the invention belong to the same inventive concept as the plunger pump zero position calibration method for blood pump perfusion cleaning provided by the invention, so the blood pump perfusion cleaning equipment and the blood pump system provided by the invention have all the advantages of the plunger pump zero position calibration method for blood pump perfusion cleaning provided by the invention, and the beneficial effects of the blood pump perfusion cleaning equipment and the blood pump system provided by the invention are not repeated.
Drawings
It will be appreciated by those skilled in the art that the drawings are provided for a better understanding of the invention and do not constitute any limitation to the scope of the invention. Wherein:
FIG. 1 is a schematic diagram of the overall configuration of a blood pump system according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of the overall structure of a plunger pump according to an embodiment of the invention;
FIG. 3 is a schematic diagram of a drive configuration for a plunger pump according to an embodiment of the present invention;
FIG. 4 is a schematic view showing the installation positions of two one-way opening suction valves and discharge valves of a plunger pump according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of an external configuration of a plunger pump according to an embodiment of the present invention;
fig. 6 is a schematic view of the internal structure of a plunger pump according to an embodiment of the present invention;
fig. 7 is a flow chart of a zero calibration method of a plunger pump according to an embodiment of the invention.
In the drawings:
1-a blood pump assembly; 2-a delivery catheter; 3-a wire collecting box; 4-flushing the pipeline; 5-a purified solution supply device; 6-a blood pump perfusion cleaning device; 601-a housing; 602-a plunger pump; 6021-plunger; 6022-jar body; 6023-sealed volume; 6024-proximal pipette port; 6025-suction valve; 6026-outlet valve; 6027-drive arrangement; 60271-motor drive interface; 60272-motor drive rod; 60273-gear; 60274-rack; 6028-distal drain port; 6029-base; 7-control the host computer.
Detailed Description
To further clarify the objects, advantages and features of the present invention, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. It is to be noted that the drawings are in greatly simplified form and are not to scale, but are merely intended to facilitate and clarify the explanation of the embodiments of the present invention. Further, the structures illustrated in the drawings are often part of actual structures. In particular, the drawings may have different emphasis points and may sometimes be scaled differently.
As used herein, the singular forms "a", "an" and "the" include plural referents, the term "or" is generally employed in its sense including "and/or", the terms "a" and "an" are generally employed in their sense including "at least one", the terms "at least two" are generally employed in their sense including "two or more", and further, the term "proximal" is generally the end that is closer to the operator, i.e., the end that is further from the heart; the term "distal" is generally the end near the patient, i.e., the end near the heart; "one end" and "the other end" and "proximal end" and "distal end" generally refer to the corresponding two parts, which include not only the end points, but also the terms "mounted", "connected" and "connected" should be understood broadly, for example, they may be fixed connection, detachable connection, or integrated; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. Furthermore, as used in the present invention, the disposition of an element with another element generally only means that there is a connection, coupling, fit or driving relationship between the two elements, and the connection, coupling, fit or driving relationship between the two elements may be direct or indirect through intermediate elements, and cannot be understood as indicating or implying any spatial positional relationship between the two elements, i.e., an element may be in any orientation inside, outside, above, below or to one side of another element, unless the content clearly indicates otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
The core idea of the invention is to provide a plunger pump zero calibration method for perfusion cleaning of a blood pump, perfusion cleaning equipment of the blood pump and the blood pump system, so as to solve the problems that the reciprocating movement distance of the plunger pump cannot be accurately controlled, the proximal end surface of a plunger easily collides with the proximal end of a housing and the distal end surface of the plunger is easily abraded in the prior art.
The following description is made with reference to the accompanying drawings, and features in the embodiments and the embodiments described below may be supplemented with each other or combined with each other without conflict.
Fig. 1 is a schematic structural diagram of a blood pump system according to an embodiment of the present invention. As shown in fig. 1, the blood pump system comprises a blood pump assembly 1, a conveying conduit 2, a hub 3, a flushing pipeline 4, a purifying solution supply device 5 and a blood pump perfusion cleaning device 6. The perfusion cleaning device 6 includes a housing 601 and a plunger pump 602 disposed in the housing 601.
The proximal end of the blood pump assembly 1 is connected with the distal end of the delivery catheter 2, i.e. the blood pump assembly 1 is arranged at the distal end of the delivery catheter 2. When the blood pump assembly 1 is implanted, the blood pump assembly 1 can enter from femoral artery or subclavian artery of a human body, and finally the blood pump assembly 1 is pushed into the left ventricle. The blood pump assembly 1 has a blood inflow port and a blood outflow port. After the blood pump assembly 1 is implanted, the blood inflow port of the blood pump assembly 1 may be located in the left ventricle and the blood outflow port of the blood pump assembly 1 may be located in the aorta. Blood enters the blood pump assembly 1 through the blood flow inlet, and after an impeller blade in the blood pump assembly 1 does work, the blood flows out at a high speed from the blood flow outlet, the blood flowing out at a high speed easily enters the inside of a motor rotor in the blood pump assembly 1 or enters a gap between a motor stator and the rotor, and the blood is solidified in the inside of the rotor or in the gap between the stator and the rotor, so that the blood pump assembly 1 is stopped suddenly. Therefore, in the working process of the blood pump assembly 1, the purified liquid needs to be continuously released to the blood pump assembly 1 through the flushing pipeline 4, so that blood is prevented from being solidified inside the rotor of the blood pump assembly 1 or in the gap between the stator and the rotor, and the blood pump assembly 1 stops working.
The flushing line 4 passes through the hub 3, extends along the delivery conduit 2 and is connected to the proximal end of the blood pump assembly 1. The most proximal end of the flushing line 4 is provided with a supply 5 of a purification solution. The cleaning solution supply means 5 is for supplying a cleaning liquid. The plunger pump 602 is connected with the flushing pipeline 4, if the plunger pump 602 is arranged on the flushing pipeline 4, after the plunger pump 602 is used for doing work to the purified liquid, the purified liquid is pushed to the blood pump assembly 1 through the flushing pipeline 4, that is, the blood pump assembly 1 can be washed by filling the purified liquid, but the purified liquid includes but is not limited to heparin or glucose solution.
Fig. 2 is a schematic overall structure diagram of the plunger pump 602 according to the embodiment of the present invention, fig. 3 is a schematic transmission structure 6027 of the plunger pump 602 according to the embodiment of the present invention, and fig. 4 is a schematic installation position diagram of two check valves of the plunger pump 602 according to the embodiment of the present invention.
As shown in fig. 1-4, the plunger pump 602 is an axial plunger pump that varies the seal volume 6023 by the reciprocating movement of the plunger 6021 within the cylinder 6022 to achieve both liquid intake and liquid discharge. The purified liquid in the purified solution supply means 5 passes through the flush line 4 to the proximal pipette port 6024 of the plunger pump 602. The plunger 6021 moves toward the proximal end of the plunger pump 602 to enlarge the seal volume 6023 and purge fluid is drawn into the seal volume 6023 via the suction valve 6025. The plunger 6021 moves distally, the seal volume 6023 decreases, and the purified liquid exits the seal volume 6023 through the outlet valve 6026. The suction valve 6025 and the discharge valve 6026 are one-way valves, and the suction valve 6025 allows only the flow of the purified liquid from the proximal liquid suction port 6024 to the distal end and does not allow the backflow; the drain valve 6026 allows only the flow of the purified liquid from the proximal end to the distal drain port 6028, and does not allow the backflow.
Plunger 6021 is typically driven in reciprocating motion by a motor. The motor is a rotating motor and is mostly a stepping motor. At this time, the plunger pump 602 further includes a transmission structure 6027, and the transmission structure 6027 includes a motor transmission interface 60271, a motor transmission rod 60272, a gear 60273, and a rack 60274. The motor transmission interface 60271 and the gear 60273 are sleeved on the motor transmission rod 60272 and are coaxially arranged. The motor drive interface 60271 is connected with the motor shaft. The motor drives gear 60273 to rotate. Gear 60273 meshes with rack 60274 on plunger 6021, and gear 60273 rotates to drive rack 60274 to move. Rack 60274 moves to drive plunger 6021 to move.
Fig. 5 is an external view of a plunger pump 602 according to an embodiment of the invention. As shown in FIG. 5, during clinical use, the plunger pump 602 is enclosed by the housing 601 so that the position of the proximal face of the plunger cannot be directly seen by the naked eye, and during use, if the operator moves the plunger 6021 blind forward (distally) or backward (proximally), the plunger 6021 may be damaged by impact. Thus, in use, it is necessary to ensure that plunger 6021 is at a zero position from which it is precisely controlled that plunger 6021 moves toward the proximal end of plunger pump 602 to avoid the proximal face of the plunger striking the proximal end of the housing; after proximal movement, it is also desirable to ensure that the plunger 6021 returns to a zero position to avoid wear of the plunger distal surface. Although the zero position of the plunger 6021 is calibrated when the plunger pump 602 leaves the factory, in actual use, there is no way to know whether the plunger 6021 is in the zero position calibrated when leaving the factory, because the plunger pump 602 may move after leaving the factory, in addition, the control host 7 is abnormally stopped, the plunger pump 602 is suddenly stopped in the operation process, the control host 7 cannot timely store the end surface position of the plunger pump 602, the plunger 602 is also not in the zero position, and at this time, the plunger pump 602 is wrapped by the housing 601, and the operator cannot know the distance between the near end surface of the plunger 6021 and the near end of the housing.
If the position of the plunger proximal end surface is not clear, the distance that the plunger 6021 moves proximally cannot be accurately controlled, and at this time, if the distance that the plunger 6021 moves proximally is too large, the plunger proximal end surface may hit the housing proximal end, resulting in damage to the plunger 6021. In addition, if the position of the proximal end face of the plunger is not clear, the distance of the distal movement of the plunger 6021 cannot be accurately controlled, which may result in a deviation between the infusion amount of the irrigation solution and the infusion amount of the heparin solution, increase the possibility of thrombosis, and may result in damage to the irrigation system, such as tooth breakage of the rack-and-pinion mechanism, or cause the plunger to flush out of the distal end face of the cylinder, resulting in damage to the plunger, and finally in a failure of the function of the irrigation system. At the same time, plunger 6021 moves distally too much, and the distal face of the plunger is susceptible to wear. Because the plunger 6021 is disposed within the cannula, the heat-shrunk outer diameter of the cannula tip is reduced due to the cutting process of the cannula, and the plunger distal end face is susceptible to wear if the plunger 6021 is moved toward the cannula tip.
To this end, according to an embodiment of the present invention, a plunger pump zero calibration method for blood pump perfusion cleaning is provided, and is applied to a blood pump perfusion cleaning device 6 and executed by a control host 7 in the blood pump perfusion cleaning device 6. The zero position of the plunger 6021 can be recalibrated by the plunger pump zero position calibration method. Before the plunger pump 6021 is started each time, the plunger 6021 is already positioned at the zero position, and the plunger pump 602 can be started after the zero position is reached, so that the reciprocating distance of the plunger pump 602 is accurately controlled, the infusion and cleaning of the blood pump assembly 1 are realized, the infusion amount of the infusion washing liquid and the infusion amount of the heparin solution can be accurately controlled, the abrasion of the distal end surface of the plunger is reduced, the collision between the proximal end surface of the plunger and the proximal end of the housing can be avoided, and the risk of plunger damage is reduced. It will be appreciated that the recalibrated plunger zero position may or may not be the same as the factory zero position of the plunger pump 602.
Fig. 7 is a flowchart of a zero calibration method for a plunger pump according to an embodiment of the invention. As shown in fig. 7, the zero calibration method for the plunger pump includes the following steps:
step S1, controlling the plunger 6021 to move toward the proximal end of the plunger pump 602;
step S2, in the process that the plunger 6021 moves towards the near end, the position of the near end face of the plunger relative to the near end of the housing is sensed, if the position of the near end face of the plunger meets a preset condition, the plunger 6021 is controlled to stop moving, and the position of the near end face of the plunger at the moment is determined as a near end limit position;
step S3, controlling the plunger 6021 to move to a preset position towards the far end of the plunger pump 602 according to the near end limit position;
and step S4, after the preset position is reached, controlling the plunger 6021 to stop moving, and determining the position of the distal end surface of the plunger at the moment as the plunger zero position or determining the position of the proximal end surface of the plunger at the moment as the plunger zero position.
In this manner, the problem of plunger collision damage that can result from blind forward (i.e., distal) or backward (i.e., proximal) movement of plunger 6021 during clinical use is addressed. Specifically, knowing the plunger zero position, the distance that plunger 6021 moves proximally can be precisely controlled, preventing the proximal face of the plunger from colliding with the proximal end of the housing; knowing the proximal limit position, the distance that plunger 6021 moves distally can be precisely controlled, reducing the risk of plunger distal face wear. In specific implementation, the plunger pump 602 can be started to fill and clean the blood pump assembly 1 only when the plunger 6021 reaches the recalibrated zero position.
It will be appreciated that the position of the plunger distal face after the preset position is reached may be determined by the stroke of distal movement of the plunger 6021 and the plunger length. The stroke of the plunger to the distal end is set primarily to ensure that the purging liquid is adequately drained from the seal volume 6023 and to avoid the distal end surface of the plunger from colliding and wearing away.
In the present embodiment, the plunger 6021 is controlled by the motor, but the present invention does not exclude the case where the plunger 6021 is not controlled by the motor, which is also within the scope of the present invention. Taking motor driving as a schematic illustration, when the plunger 6021 is driven by the motor to move during zero calibration, if the stroke of the distal movement and the proximal limit position of the plunger 6021 are known, the number of turns of the motor required to rotate can be calculated according to the motion conversion relationship between the gear 60273 and the rack 60274, so as to obtain the preset position. In this embodiment, the target number of turns N of the motor may be 1-3 when the control plunger 6021 is moved distally. During the filling and cleaning process, the reciprocating distance of the plunger pump 602 can be precisely controlled by controlling the number of the reverse and forward rotation turns of the motor.
Further, the plunger pump zero calibration method can further comprise the following steps: the motor controls the plunger 6021 to move towards the near end, generates a trigger signal when the position of the near end surface of the plunger meets a preset condition, and enables the motor to stop running in response to the trigger signal, so that the plunger 6021 stops moving; and the plunger 6021 is controlled by the motor to move distally, and after reaching a preset position, the motor stops operating, thereby stopping the movement of the plunger 6021. In this way the proximal end limit position can be determined quickly and accurately.
Further, the predetermined condition is preferably that the proximal end face of the plunger touches or is about to touch the proximal end of the housing. Touching the proximal end of the housing is to be understood as meaning that the proximal end face of the plunger does not yet touch the proximal end of the housing, but the distance between the two is very small and is in the state of being touched.
Further, the plunger pump zero calibration method can further comprise the following steps: the motor driven plunger 6021 is controlled by the control master 7 to move proximally or distally, and the control master 7 is further configured to send the trigger signal to the motor to stop the motor in response to the trigger signal.
Further, the plunger pump zero calibration method is used for being executed when the blood pump perfusion cleaning equipment is started for the first time or when the blood pump perfusion cleaning equipment is started again after the control host is abnormally relieved. Although the plunger pump 602 is calibrated to the zero position of the plunger 6021 when leaving the factory, in actual use, there is no way to know whether the plunger 6021 is already at the zero position calibrated when leaving the factory, because the plunger pump 602 may move after leaving the factory, the plunger pump zero position calibration method is executed when the blood pump perfusion cleaning device is first started. In addition, when the control master 7 is abnormal, the operation of the plunger pump 602 is suddenly stopped, and the control master 7 cannot timely store the end surface position of the plunger pump 602. At the time when plunger 6021 is not in the zero position and when plunger pump 602 is again enclosed by housing 601, the operator is not aware of the distance between the proximal face of the plunger and the proximal end of the housing. The abnormal condition of the control host 7 related to the present invention is not particularly limited, and may be a situation that the plunger pump 602 suddenly stops moving and the control host 7 fails to collect the position of the plunger pump 602 in time.
Fig. 6 shows an opened internal structure of the cover 601 according to the embodiment of the present invention. As shown in fig. 6, a hollow cylinder 6011 extending toward the plunger 6021 is provided on the inner wall of the housing proximal end, and the hollow cylinder 6011 is used for exhausting, i.e., as an exhaust hole. In this embodiment, the predetermined condition is that the plunger proximal end surface touches or is about to touch the inside end surface of the hollow cylinder 6021, that is, when the plunger proximal end surface touches or is about to touch the inside end surface of the hollow cylinder 6021, the plunger 6021 does not move proximally any more, thereby determining the proximal end limit position. The axis of the hollow cylinder 6011 is collinear with the axis of the plunger 6021.
In this embodiment, the zero calibration of the plunger 6021 may be implemented as follows:
a first step; the motor is started, the motor drives the gear 60273 to rotate, and the gear 60273 drives the plunger 6021 to move towards the proximal end of the plunger pump 602 through the rack 60274; during the process that the plunger 6021 moves towards the near end, the position of the near end face of the plunger relative to the inner end face of the hollow cylinder 6021 is sensed, if the position of the near end face of the plunger meets the preset condition that the near end face of the plunger touches the inner end face of the hollow cylinder 6021 or is about to touch the inner end face of the hollow cylinder 6021, the motor stops rotating, and the position of the near end face of the plunger at the moment is determined as a near end limit position;
the second step is that: knowing the proximal end limit position of plunger 6021, motor controls gear 60273 to revolve, gear 60273 drives plunger 6021 via rack 60274 to move distally to a preset position, after the preset position is reached, the motor stops rotating and determines the position of the distal end face of plunger 6021 at the preset position as plunger zero position or the position of the proximal end face of plunger 6021 at the preset position as plunger zero position.
Further, the preset position is determined according to the near-end limit position and the stroke of the plunger moving towards the far end, the target number of turns of the motor is obtained, and in the process that the plunger 6021 moves towards the far end, if the actual number of turns of the motor reaches the target number of turns of the motor, the motor stops running.
It should be noted that the present application is not limited to a particular implementation of sensing the position of the proximal end face of the plunger relative to the proximal end of the housing, and may be implemented in a variety of ways as will be appreciated by those skilled in the art. For ease of understanding, how the position of the proximal face of the plunger is sensed relative to the proximal end of the housing is further described herein in the following sensing manners. It should be appreciated that other configurations of sensing the position of the proximal face of the plunger relative to the proximal end of the housing are also contemplated and are intended to be within the scope of the present application.
In one embodiment, the blood pump perfusion washing device 6 further comprises an in-position sensor (not shown) that senses a position of the proximal end face of the plunger relative to the proximal end of the housing (e.g., the inner end face of the hollow cylinder 6021), and the in-position sensor is triggered when the position of the proximal end face of the plunger meets a predetermined condition that the proximal end face of the plunger touches the proximal end of the housing, and generates a trigger signal according to an event that the in-position sensor is triggered.
The present application does not require any particular type of in-place sensor, for example, the in-place sensor can be any suitable structure such as a mechanical switch, an electronic switch, an electro-optical switch, etc., as long as the proximal movement of plunger 6021 contacts the housing proximal end to trigger the in-place sensor. In an implementation, one of the proximal end surfaces of the casing and the plunger is provided with an in-position sensor, for example, in this embodiment, the inner end surface of the hollow cylinder 6011 is provided with an in-position sensor, and the in-position sensor is triggered when the in-position sensor is pressed by the proximal end surface of the plunger.
In one embodiment, the perfusion washing device 6 further comprises a distance sensor (not shown) for sensing the distance between the proximal end surface of the plunger and the proximal end surface of the housing (e.g., the inner end surface of the hollow cylinder 6021), determining the position of the proximal end surface of the plunger relative to the proximal end of the housing according to the distance, and generating a trigger signal when the distance between the proximal end surfaces of the plunger meets a preset condition that the proximal end surface of the plunger touches or is about to touch the proximal end of the housing.
The application has no special requirements on the types of the distance sensors, and any sensing element capable of sensing the distance between objects can be adopted, such as an optical distance sensor, an infrared distance sensor, an ultrasonic distance sensor and the like. In a specific implementation, one of the housing proximal end and the plunger proximal end surface is provided with a distance sensor, for example, in this embodiment, a distance sensor is provided on the inner end surface of the hollow cylinder 6011 to measure the distance between the plunger proximal end surface and the inner end surface of the hollow cylinder 6011. The motor stalls when the plunger proximal end face comes into contact with the inside end face of the hollow cylinder 6011 (i.e., a distance of 0), or both, approaches 0.
In one embodiment, the blood pump perfusion cleaning apparatus 6 further comprises a force sensor, the force sensor senses a stress state of the proximal end of the housing and/or the plunger pump 602, determines a position of the proximal end face of the plunger relative to the proximal end of the housing according to the stress state, and generates a trigger signal when a stress value corresponding to the stress state meets a preset condition that the proximal end face of the plunger touches the proximal end of the housing. In this embodiment, when the proximal end surface of the plunger contacts the inner end surface of the hollow cylinder 6011, the inner end surface of the hollow cylinder 6011 is stressed, and at this time, the distal end surface of the base 6029 supporting the motor transmission rod 60272 is also stressed, so that a force sensor may be disposed on the inner end surface of the hollow cylinder 6011 or the distal end surface of the base 6029, and the force sensor may sense a stress state of the inner end surface of the hollow cylinder 6011 or the distal end surface of the base 6029. If the force value of the inboard end face of hollow cylinder 6011, and/or of base 6029, suddenly increases, it indicates that the plunger proximal end face touches the inboard end face of hollow cylinder 6011. The force sensor is typically a pressure sensor, such as a pressure sensor sensing the axial direction.
In one embodiment, the perfusion washing device 6 further comprises a torque sensor, wherein the torque sensor senses the output torque of the motor, determines the position of the proximal end face of the plunger relative to the proximal end of the housing according to the output torque, and generates a trigger signal when the output torque meets a preset condition that the proximal end face of the plunger touches the proximal end of the housing. Further, a torque sensor is arranged on the motor transmission rod 60272 and used for sensing torque on the motor transmission rod 60272, and if the sensed torque exceeds a normal value, the plunger proximal end face touches the end face of the inner side of the hollow cylinder 6011, so that output torque is increased.
In another embodiment, the blood pump perfusion washing device 6 further comprises a sensor that detects a voltage or current. During proximal movement of plunger 6021, an electrical output signal (e.g., voltage or current) from the motor is sensed, and a position of the proximal face of the plunger relative to the proximal end of the housing is determined based on the electrical output signal, and a trigger signal is generated when the electrical output signal satisfies a predetermined condition that the proximal face of the plunger touches the proximal end of the housing. If the motor is a stepping motor, the current is stable when the motor operates normally, and if the current output is abnormal when the stepping motor loses steps, it indicates that the proximal end face of the plunger touches the end face of the inner side of the hollow cylinder 6011. In this embodiment, a voltage sensor may be used to sense the output voltage of the motor, and if the output voltage is abnormal, it indicates that the proximal end surface of the plunger touches the inner end surface of the hollow cylinder 6011, or a current sensor may be used to sense the output current of the motor, and if the output current is abnormal, it indicates that the proximal end surface of the plunger touches the inner end surface of the hollow cylinder 6011.
It should be appreciated that the blood pump perfusion cleaning device 6 may include at least one of an in-position sensor, a distance sensor, a force sensor, a torque sensor, a voltage sensor, and a current sensor.
Further, the present invention also provides a readable storage medium, which stores a program, and the program is executed by a processor to implement the above plunger pump zero calibration method. The programs, which may also be referred to as computer programs, software applications, components, or code, include machine instructions for a programmable processor, and may be implemented in a high-level procedural, object-oriented programming, or assembly/machine language. As used herein, a readable storage medium refers to any computer program product, apparatus and/or device for providing machine instructions, such as magnetic disks, optical disks, memory and Programmable Logic Devices (PLDs), and/or data to a programmable processor, including a machine-readable medium that receives machine instructions as a machine-readable signal.
As shown in fig. 1, the present invention further provides a control host 7, which may include a processor, a memory, and a program stored in the memory and running on the processor, and when the processor executes the program, the processor implements the plunger pump zero calibration method described above. The present embodiment is not particularly limited as to the type of processor, which may comprise any type of microprocessor or Central Processing Unit (CPU), including programmable general purpose or special purpose microprocessors and/or any of a variety of proprietary or commercial single or multi-processor systems. The present embodiment is not particularly limited as to the type of memory, which may include Read Only Memory (ROM), flash memory, one or more types of Random Access Memory (RAM) (e.g., static RAM (SRAM), dynamic RAM (DRAM), or Synchronous DRAM (SDRAM)), and/or a combination of memory technologies.
The invention also provides a blood pump perfusion cleaning device which comprises a housing 601, a plunger 602 pump, a sensor and a control host 7. The control host is disposed outside the housing 601 and is disposed independently of other devices. The control host 601 can be used for realizing zero calibration of the plunger pump, and can also be used as a control center of a blood pump system.
Further, the blood pump perfusion cleaning device 6 further comprises a motor which is in communication connection with the control host 7. The motor is connected with a motor transmission interface 60271; the control host 7 is used to control the motor to drive the plunger 6021 to move towards the proximal end or the distal end, and is also used to send a trigger signal to the motor, so that the motor stops running in response to the trigger signal. Further, in the process that the plunger 6021 moves towards the proximal end, the control host 7 may determine whether the position of the proximal end surface of the plunger meets the preset condition, and if so, the control host 7 sends a trigger signal to the motor and records the position of the proximal end surface of the plunger at this time as the proximal end limit position. Further, in the process that the plunger 6021 moves towards the far end, the control host 7 can judge whether the actual number of turns of the motor reaches the target number of turns of the motor, if so, the control host 7 sends a signal to the motor to stop the motor in response to the control signal of the control host 7, and the control host 7 records the position of the distal end surface of the plunger at the moment as the plunger zero position. It should also be understood that the parameters during zero calibration and the parameters during perfusion and cleaning of the blood pump can be stored in the memory of the control host 7, and the processor can read the information in the memory to perform zero calibration or perfusion and cleaning.
To sum up, when the perfusion cleaning equipment of the blood pump is started for the first time or the perfusion cleaning equipment is started again after the control host is abnormally relieved, the plunger pump zero calibration method provided by the invention can be adopted to carry out zero calibration on the plunger, and the plunger pump can be normally started to perfuse and clean the blood pump only after the plunger reaches the calibrated zero, so that the reciprocating motion distance of the plunger pump is accurately controlled, the risk of collision between the proximal end surface of the plunger and the proximal end of the housing is reduced, the risk of abrasion of the distal end surface of the plunger is reduced, and the risk of plunger damage is further reduced.
The blood pump perfusion cleaning equipment and the blood pump system provided by the invention belong to the same inventive concept as the plunger pump zero position calibration method provided by the invention, so the blood pump perfusion cleaning equipment and the blood pump system provided by the invention have all the advantages of the plunger pump zero position calibration method provided by the invention, and the beneficial effects of the blood pump perfusion cleaning equipment and the blood pump system provided by the invention are not repeated.
It should also be noted that, although the present invention has been described with reference to the preferred embodiments, the above-mentioned embodiments are not intended to limit the present invention. It will be apparent to those skilled in the art from this disclosure that many changes and modifications can be made, or equivalents modified, in the embodiments of the invention without departing from the scope of the invention. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention are still within the protection scope of the technical solution of the present invention, unless the content of the technical solution of the present invention is departed from.

Claims (14)

1. A plunger pump zero-position calibration method for perfusion cleaning of a blood pump, wherein a plunger pump is arranged in a housing, and is characterized by comprising the following steps:
controlling a plunger of the plunger pump to move towards a proximal end of the plunger pump;
in the process that the plunger moves towards the near end, the position of the near end face of the plunger relative to the near end of the housing is sensed, if the position of the near end face of the plunger meets a preset condition, the plunger is controlled to stop moving, and the position of the near end face of the plunger at the moment is determined as a near end limit position;
controlling the plunger to move to a preset position towards the distal end of the plunger pump according to the proximal end limit position;
and after the preset position is reached, controlling the plunger to stop moving, and determining the position of the distal end surface of the plunger at the moment as the plunger zero position or determining the position of the proximal end surface of the plunger at the moment as the plunger zero position.
2. The plunger pump zero calibration method for perfusion cleaning of a blood pump as claimed in claim 1, further comprising:
the plunger is controlled by a motor to move towards the proximal end, a trigger signal is generated when the position of the proximal end face of the plunger meets a preset condition, the motor is made to stop running in response to the trigger signal, and then the plunger stops moving;
the motor controls the plunger to move towards the far end, and after the plunger reaches the preset position, the motor stops operating, so that the plunger stops moving.
3. The plunger pump zero calibration method for perfusion cleaning of a blood pump according to claim 2, wherein the preset condition is that the proximal end face of the plunger touches or is about to touch the proximal end of the housing.
4. The plunger pump zero calibration method for perfusion cleaning of a blood pump as claimed in claim 2, further comprising:
determining the preset position according to the near-end limit position and the stroke of the plunger moving towards the far end, and acquiring the target number of turns of the motor;
and in the process that the plunger moves towards the far end, if the actual number of turns of the motor reaches the target number of turns of the motor, the motor stops running.
5. The plunger pump zero calibration method for perfusion cleaning of a blood pump according to claim 2, characterized in that the position of the plunger proximal end surface relative to the housing proximal end is sensed by an in-position sensor, the in-position sensor is triggered when the position of the plunger proximal end surface meets the preset condition that the plunger proximal end surface touches the housing proximal end, and the trigger signal is generated according to the event that the in-position sensor is triggered, wherein the in-position sensor is arranged on one of the housing proximal end surface and the plunger proximal end surface.
6. The plunger pump zero calibration method for perfusion cleaning of a blood pump according to claim 2, characterized in that the distance between the proximal end surface of the plunger and the proximal end surface of the housing is sensed by a distance sensor, the position of the proximal end surface of the plunger relative to the proximal end of the housing is determined according to the distance, and the trigger signal is generated when the distance between the proximal end surface of the plunger meets the preset condition that the proximal end surface of the plunger touches or is about to touch the proximal end of the housing, wherein one of the proximal end surface of the housing and the proximal end surface of the plunger is provided with the distance sensor.
7. The plunger pump zero calibration method for perfusion cleaning of a blood pump according to claim 2, characterized in that a force sensor is used to sense a stress state of the housing proximal end and/or the plunger pump, and the position of the plunger proximal end surface relative to the housing proximal end is determined according to the stress state, and the trigger signal is generated when a stress value corresponding to the stress state meets the preset condition that the plunger proximal end surface touches the housing proximal end, wherein the force sensor is provided on at least one of the housing proximal end and a base of the plunger pump, and the base supports a motor transmission rod.
8. The plunger pump zero calibration method for perfusion cleaning of a blood pump as claimed in claim 2, wherein a torque sensor is disposed on a motor transmission rod of the plunger pump, and is used for sensing an output torque of the motor, determining a position of the proximal end surface of the plunger relative to the proximal end of the housing according to the output torque, and generating the trigger signal when the output torque meets the preset condition that the proximal end surface of the plunger touches the proximal end of the housing.
9. The plunger pump zero calibration method for perfusion cleaning of a blood pump as claimed in claim 2, wherein during the proximal movement of the plunger, an output electrical signal of the motor is sensed, the position of the proximal end face of the plunger relative to the proximal end of the housing is determined according to the output electrical signal, and the trigger signal is generated when the output electrical signal meets the preset condition that the proximal end face of the plunger touches the proximal end of the housing.
10. The plunger pump zero calibration method for perfusion cleaning of a blood pump as claimed in claim 2, wherein the motor is controlled by a control host to drive the plunger to move towards the proximal end or the distal end, and the control host is further used for sending the trigger signal to the motor to stop the motor in response to the trigger signal.
11. The plunger pump zero calibration method for the perfusion cleaning of the blood pump according to any one of claims 1 to 10, wherein the plunger pump zero calibration method is executed when the perfusion cleaning device of the blood pump is started for the first time or when the perfusion cleaning device of the blood pump is started again after the abnormality of the control host is relieved.
12. A blood pump perfusion cleaning device comprises a housing, a plunger pump, a sensor and a control host, wherein the plunger pump is arranged in the housing; the control host is arranged outside the housing; at least one of the housing and the plunger pump is provided with the sensor; the sensor is used for sensing the position of the plunger proximal end face relative to the housing proximal end during the proximal movement of the plunger; the control host is used for executing the plunger pump zero calibration method for perfusion cleaning of the blood pump as claimed in any one of claims 1 to 11.
13. The perfusion cleaning device of the blood pump according to claim 12, further comprising a motor communicatively coupled to the control host; the motor is connected with a motor transmission interface of the plunger pump; the control host is used for controlling the motor to drive the plunger to move towards the near end or the far end, and is also used for sending a trigger signal to the motor, so that the motor stops running in response to the trigger signal.
14. A blood pump system comprising a blood pump assembly, a delivery conduit, a hub, a flush line, and the blood pump perfusion cleaning device of claim 12 or 13; the blood pump assembly is disposed at the distal end of the delivery catheter; the flushing pipeline penetrates through the junction box, extends along the conveying conduit and is connected with the proximal end of the blood pump assembly; the plunger pump of the blood pump perfusion cleaning equipment is arranged on the flushing pipeline and used for pushing the purified liquid to the blood pump assembly through the flushing pipeline.
CN202211613753.0A 2022-12-15 2022-12-15 Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system Pending CN115807766A (en)

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CN202211613753.0A CN115807766A (en) 2022-12-15 2022-12-15 Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system

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Application Number Priority Date Filing Date Title
CN202211613753.0A CN115807766A (en) 2022-12-15 2022-12-15 Plunger pump zero calibration method, blood pump perfusion cleaning equipment and blood pump system

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CN115807766A true CN115807766A (en) 2023-03-17

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