CN115736106A - Compound choline chloride acidifier solution and preparation method thereof - Google Patents
Compound choline chloride acidifier solution and preparation method thereof Download PDFInfo
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- CN115736106A CN115736106A CN202211538201.8A CN202211538201A CN115736106A CN 115736106 A CN115736106 A CN 115736106A CN 202211538201 A CN202211538201 A CN 202211538201A CN 115736106 A CN115736106 A CN 115736106A
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- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 title claims abstract description 71
- 235000019743 Choline chloride Nutrition 0.000 title claims abstract description 71
- 229960003178 choline chloride Drugs 0.000 title claims abstract description 71
- 239000002535 acidifier Substances 0.000 title claims abstract description 66
- -1 Compound choline chloride Chemical class 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 claims abstract description 43
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 33
- 229910052802 copper Inorganic materials 0.000 claims abstract description 33
- 239000010949 copper Substances 0.000 claims abstract description 33
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims abstract description 28
- 239000008213 purified water Substances 0.000 claims abstract description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 66
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 66
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 51
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 51
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 50
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims description 34
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 34
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 33
- 235000019253 formic acid Nutrition 0.000 claims description 33
- 239000001530 fumaric acid Substances 0.000 claims description 33
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 33
- 239000004310 lactic acid Substances 0.000 claims description 25
- 235000014655 lactic acid Nutrition 0.000 claims description 25
- 239000007788 liquid Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 18
- 235000011054 acetic acid Nutrition 0.000 claims description 17
- 235000019260 propionic acid Nutrition 0.000 claims description 17
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims description 17
- 235000011087 fumaric acid Nutrition 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 11
- 235000015165 citric acid Nutrition 0.000 claims description 8
- 239000002131 composite material Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims 1
- 241001465754 Metazoa Species 0.000 abstract description 10
- 244000144977 poultry Species 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 9
- 244000144972 livestock Species 0.000 abstract description 7
- 241000894006 Bacteria Species 0.000 abstract description 5
- 230000002401 inhibitory effect Effects 0.000 abstract description 5
- 239000003674 animal food additive Substances 0.000 abstract description 3
- 230000007413 intestinal health Effects 0.000 abstract description 3
- 230000002708 enhancing effect Effects 0.000 abstract description 2
- 230000036039 immunity Effects 0.000 abstract description 2
- 238000001727 in vivo Methods 0.000 abstract description 2
- 230000002147 killing effect Effects 0.000 abstract description 2
- 230000004060 metabolic process Effects 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 description 5
- 210000001035 gastrointestinal tract Anatomy 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 241000607142 Salmonella Species 0.000 description 3
- 230000002378 acidificating effect Effects 0.000 description 3
- 208000035240 Disease Resistance Diseases 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 230000006820 DNA synthesis Effects 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 229940095602 acidifiers Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000008558 metabolic pathway by substance Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000017448 oviposition Effects 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
Abstract
The invention discloses a compound choline chloride acidifier solution and a preparation method thereof, which relate to the technical field of preparation of feed additives, and aim to solve the technical problems that in the prior art, choline chloride, acidifier and chelated copper are used independently, cannot be synergistically promoted, and have low effect of improving the growth rate of animals, the solution comprises the following components in parts by weight: 8-12 parts of choline chloride, 360-540 parts of acidifier, 64-96 parts of chelated copper, 16-24 parts of disodium hydrogen phosphate and 400-650 parts of purified water, the choline chloride, the acidifier and the chelated copper are compounded together in the solution and the preparation method thereof, the components and functions of the solution are more comprehensive, the choline chloride, the acidifier and the chelated copper are synergistically promoted, the effect of improving the growth rate of animals is higher, the solution has the effects of inhibiting bacteria and killing bacteria, improving the intestinal health of livestock and poultry, improving the productivity of livestock and poultry, participating in-vivo metabolism regulation and enhancing the immunity, and the healthy growth of the animals is promoted by improving the growth rate of the animals.
Description
Technical Field
The invention belongs to the technical field of preparation of feed additives, and particularly relates to a compound choline chloride acidifier solution and a preparation method thereof.
Background
The choline chloride can enhance the physique and disease resistance of poultry, improve the feed conversion rate and promote the growth of the poultry, the compound acidifier mainly has the effects of inhibiting bacteria and killing bacteria and improving the intestinal health of the poultry, and the amino acid chelated copper can effectively improve the growth speed of animals, reduce the feed consumption and enhance the disease resistance.
At present, common organic acidifiers in feed are divided into two types according to characteristics, one type is an inhibitory acidifier which achieves the purpose of bacteriostasis by reducing the pH of the gastrointestinal tract environment and participating in body energy metabolism, and the other type is an inhibitory acidifier which achieves the purpose of bacteriostasis by reducing the pH of the gastrointestinal tract, destroying bacterial cell membranes, interfering with processes of bacterial substance metabolism, DNA synthesis and the like, but the development is limited by factors of single variety, multiple proportions, unstable effect and the like.
Therefore, in order to solve the problem that the growth rate of animals is low due to single ingredients and functions, it is necessary to improve the application scenario of the feed additive.
Disclosure of Invention
(1) Technical problem to be solved
Aiming at the defects of the prior art, the invention aims to provide a compound choline chloride acidifier solution and a preparation method thereof, and the solution and the preparation method thereof aim to solve the technical problems that in the prior art, choline chloride, acidifier and chelated copper are used independently, cannot be synergistically promoted, and have low effect of improving the growth rate of animals.
(2) Technical scheme
In order to solve the technical problem, the invention provides a compound choline chloride acidifying agent solution which comprises the following components in parts by weight: 8-12 parts of choline chloride, 360-540 parts of acidifier, 64-96 parts of chelated copper, 16-24 parts of disodium hydrogen phosphate and 400-650 parts of purified water.
Furthermore, the concentration of the choline chloride in the solution is 5 g/L-50 g/L, and the concentration of the disodium hydrogen phosphate in the solution is 10-30g/L.
The acidifier is any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid, wherein the concentration of the formic acid in the solution is 50 g/L-200 g/L, the concentration of the acetic acid in the solution is 50 g/L-150 g/L, the concentration of the propionic acid in the solution is 50 g/L-250 g/L, the concentration of the butyric acid in the solution is 30 g/L-100 g/L, the concentration of the lactic acid in the solution is 30 g/L-120 g/L, the concentration of the citric acid in the solution is 50 g/L-200 g/L, and the concentration of the fumaric acid in the solution is 30 g/L-150 g/L.
The preparation method of the compound choline chloride acidifying agent solution is characterized by comprising the following steps of:
the method comprises the following steps: preparing choline chloride, chelated copper, disodium hydrogen phosphate and purified water in required weight parts, and taking any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid to obtain an acidifier in required weight parts;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 100-200 r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: adding an acidifying agent into the solution I while stirring to completely dissolve the acidifying agent, adding purified water, adding liquid to 1000 parts by weight, and standing the liquid for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a composite choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
Further, the acidulant in the first step comprises formic acid, citric acid, lactic acid and fumaric acid, and the mass ratio of the formic acid to the citric acid to the lactic acid to the fumaric acid is 1:1.5:1:1.
further, the acidifying agent in the first step comprises formic acid, lactic acid and fumaric acid, and the mass ratio of the formic acid to the lactic acid to the fumaric acid is 2:0.5:2.
further, the acidifying agent in the first step comprises formic acid, acetic acid, propionic acid, butyric acid and fumaric acid, and the mass ratio of the formic acid, the acetic acid, the propionic acid, the butyric acid and the fumaric acid is 1:1:1:0.5:1.
further, the stirring time in the third step is 20-30 minutes.
(3) Advantageous effects
Compared with the prior art, the invention has the beneficial effects that: the choline chloride, the acidifier and the chelated copper are compounded together, so that the composition and the function of the solution are more comprehensive, the choline chloride, the acidifier and the chelated copper are synergistically promoted, the effect of improving the growth rate of animals is higher, the solution has the effects of inhibiting bacteria and sterilizing, improving the intestinal health of livestock and poultry, improving the productivity of the livestock and poultry, participating in-vivo metabolic regulation and enhancing the immunity, and the growth rate of the animals is improved, the utilization rate of feed is improved, the healthy growth of the animals is promoted, and the fatty liver syndrome in the later period of egg laying is prevented.
Detailed Description
The specific embodiment is a compound choline chloride acidifying agent solution, which comprises the following components in parts by weight: 8-12 parts of choline chloride, 360-540 parts of acidifier, 64-96 parts of chelated copper, 16-24 parts of disodium hydrogen phosphate and 400-650 parts of purified water.
Furthermore, the concentration of the choline chloride in the solution is 5 g/L-50 g/L, and the concentration of the disodium hydrogen phosphate in the solution is 10-30g/L.
The acidifier is any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid, wherein the concentration of the formic acid in the solution is 50 g/L-200 g/L, the concentration of the acetic acid in the solution is 50 g/L-150 g/L, the concentration of the propionic acid in the solution is 50 g/L-250 g/L, the concentration of the butyric acid in the solution is 30 g/L-100 g/L, the concentration of the lactic acid in the solution is 30 g/L-120 g/L, the concentration of the citric acid in the solution is 50 g/L-200 g/L, and the concentration of the fumaric acid in the solution is 30 g/L-150 g/L.
The preparation method of the compound choline chloride acidifying agent solution is characterized by comprising the following steps of:
the method comprises the following steps: preparing required parts by weight of choline chloride, chelated copper, disodium hydrogen phosphate and purified water, and taking any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid to obtain required parts by weight of an acidifier;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 100-200 r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: adding an acidifying agent into the solution I while stirring to completely dissolve the acidifying agent, adding purified water, adding liquid to 1000 parts by weight, and standing the liquid for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a compound choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
Further, the acidulant in the first step comprises formic acid, citric acid, lactic acid and fumaric acid, and the mass ratio of the formic acid to the citric acid to the lactic acid to the fumaric acid is 1:1.5:1:1.
further, the acidifying agent in the first step comprises formic acid, lactic acid and fumaric acid, and the mass ratio of the formic acid to the lactic acid to the fumaric acid is 2:0.5:2.
further, the acidifying agent in the first step comprises formic acid, acetic acid, propionic acid, butyric acid and fumaric acid, and the mass ratio of the formic acid, the acetic acid, the propionic acid, the butyric acid and the fumaric acid is 1:1:1:0.5:1.
further, the stirring time in the third step is 20-30 minutes.
Example 1
A composite choline chloride acidifying agent solution comprises the following components in parts by weight: 8 parts of choline chloride, 360 parts of acidifier, 64 parts of chelated copper, 16 parts of disodium hydrogen phosphate and 650 parts of purified water.
When the preparation method of the technical scheme is used for preparing the compound choline chloride acidifier solution, the steps are as follows:
the method comprises the following steps: 8 parts of choline chloride, 64 parts of chelated copper, 16 parts of disodium hydrogen phosphate and 650 parts of purified water are prepared, and the weight ratio of 1:1.5:1:1, taking 80 parts of formic acid, 120 parts of citric acid, 80 parts of lactic acid and 80 parts of fumaric acid to obtain 360 parts of an acidifier;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 200r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: sequentially adding formic acid, citric acid, lactic acid and fumaric acid into the solution I while stirring, stirring for 30 minutes to completely dissolve the acidifier, adding purified water, adding the liquid to 1000 parts by weight, and standing the liquid for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a compound choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
The compound choline chloride acidifying agent solution prepared in the embodiment 1 is a blue acidic liquid, and after the compound choline chloride acidifying agent solution is added into the feed for one month, escherichia coli in each intestinal section of livestock and poultry can be reduced, and meanwhile, the content of salmonella and escherichia coli in the intestinal tract can be effectively reduced.
Example 2
A compound choline chloride acidifying agent solution comprises the following components in parts by weight: 12 parts of choline chloride, 540 parts of acidifier, 96 parts of chelated copper, 24 parts of disodium hydrogen phosphate and 400 parts of purified water.
When the preparation method of the technical scheme is used for preparing the compound choline chloride acidifier solution, the steps are as follows:
the method comprises the following steps: preparing 12 parts of choline chloride, 96 parts of chelated copper, 24 parts of disodium hydrogen phosphate and 400 parts of purified water, wherein the weight ratio of the choline chloride to the chelated copper is 2:0.5:2, taking 240 parts of formic acid, 60 parts of lactic acid and 240 parts of fumaric acid to obtain 540 parts of acidifier;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 200r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: sequentially adding formic acid, lactic acid and fumaric acid into the solution I while stirring, stirring for 30 minutes to completely dissolve the acidifier, adding purified water, adding liquid to 1000 parts by weight, and standing for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a composite choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
The compound choline chloride acidifying agent solution prepared in the embodiment 2 is a blue acidic liquid, and after the compound choline chloride acidifying agent solution is added into the feed for one month, the villus height of each section of the small intestine of the livestock and poultry is effectively improved, and meanwhile, the content of salmonella and escherichia coli in the intestinal tract is effectively reduced.
Example 3
A composite choline chloride acidifying agent solution comprises the following components in parts by weight: 10 parts of choline chloride, 450 parts of acidifier, 80 parts of chelated copper, 20 parts of disodium hydrogen phosphate and 500 parts of purified water.
When the preparation method of the technical scheme is used for preparing the compound choline chloride acidifier solution, the steps are as follows:
the method comprises the following steps: 10 parts of choline chloride, 80 parts of chelated copper, 20 parts of disodium hydrogen phosphate and 500 parts of purified water are prepared, and the weight ratio of 1:1:1:0.5:1, taking 100 parts of formic acid, 100 parts of acetic acid, 100 parts of propionic acid, 50 parts of butyric acid and 100 parts of fumaric acid to obtain 450 parts of an acidifier;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 200r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: sequentially adding formic acid, acetic acid, propionic acid, butyric acid and fumaric acid into the solution I while stirring, stirring for 30 minutes to completely dissolve the acidifier, adding purified water, adding the liquid to 1000 parts by weight, and standing the liquid for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a compound choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
The compound choline chloride acidifying agent solution prepared in the example 3 is a blue acidic liquid, and after the compound choline chloride acidifying agent solution is added into the feed for one month, escherichia coli in each intestinal section of livestock and poultry can be reduced, the villus height of each section of small intestine can be improved, and the contents of salmonella and escherichia coli in the intestinal tract can be obviously reduced.
Claims (8)
1. The composite choline chloride acidifying agent solution is characterized by comprising the following components in parts by weight: 8-12 parts of choline chloride, 360-540 parts of acidifier, 64-96 parts of chelated copper, 16-24 parts of disodium hydrogen phosphate and 400-650 parts of purified water.
2. The composite choline chloride acidulant solution as claimed in claim 1, wherein the concentration of choline chloride in the solution is 5-50 g/L, and the concentration of disodium hydrogen phosphate in the solution is 10-30g/L.
3. The compound choline chloride acidulant solution according to claim 1, wherein the acidulant is any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid, wherein the concentration of formic acid in the solution is 50 g/L-200 g/L, the concentration of acetic acid in the solution is 50 g/L-150 g/L, the concentration of propionic acid in the solution is 50 g/L-250 g/L, the concentration of butyric acid in the solution is 30 g/L-100 g/L, the concentration of lactic acid in the solution is 30 g/L-120 g/L, the concentration of citric acid in the solution is 50 g/L-200 g/L, and the concentration of fumaric acid in the solution is 30 g/L-150 g/L.
4. The process for preparing a complex choline chloride acidulant solution as claimed in claim 1, wherein the steps are as follows:
the method comprises the following steps: preparing choline chloride, chelated copper, disodium hydrogen phosphate and purified water in required weight parts, and taking any two or more of formic acid, acetic acid, propionic acid, butyric acid, lactic acid, citric acid and fumaric acid to obtain an acidifier in required weight parts;
step two: pouring 60% of purified water into a liquid preparation tank, sequentially adding choline chloride, disodium hydrogen phosphate and chelated copper, starting a stirrer, and setting the stirring speed to be 100-200 r/min to fully dissolve the choline chloride, the disodium hydrogen phosphate and the chelated copper to obtain a first solution;
step three: adding an acidifying agent into the solution I while stirring to completely dissolve the acidifying agent, adding purified water, adding liquid to 1000 parts by weight, and standing the liquid for 30 minutes to obtain a solution II;
step four: filtering the second solution by using an organic filter membrane of 0.45 mu m to obtain a compound choline chloride acidifying agent solution;
step five: and (4) subpackaging the finished product solution into containers with specified specifications, and then warehousing.
5. The method for preparing the compound choline chloride acidulant solution as claimed in claim 4, wherein the acidulant in the step one comprises formic acid, citric acid, lactic acid and fumaric acid, and the mass ratio of the formic acid to the citric acid to the lactic acid to the fumaric acid is 1:1.5:1:1.
6. the method for preparing the compound choline chloride acidulant solution as claimed in claim 4, wherein the acidulant in the first step comprises formic acid, lactic acid and fumaric acid, and the mass ratio of formic acid, lactic acid and fumaric acid is 2:0.5:2.
7. the method for preparing the compound choline chloride acidulant solution as claimed in claim 4, wherein the acidulant in the first step comprises formic acid, acetic acid, propionic acid, butyric acid and fumaric acid, and the mass ratio of formic acid, acetic acid, propionic acid, butyric acid and fumaric acid is 1:1:1:0.5:1.
8. the method for preparing the compound choline chloride acidulant solution as claimed in claim 4, wherein the stirring time in the third step is 20-30 minutes.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115104674A (en) * | 2021-03-19 | 2022-09-27 | 山东菏泽三仪生物工程有限公司 | Preparation method and application of composite organic acidifier |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115104674A (en) * | 2021-03-19 | 2022-09-27 | 山东菏泽三仪生物工程有限公司 | Preparation method and application of composite organic acidifier |
Non-Patent Citations (2)
| Title |
|---|
| 吴志青等: "氨基酸铜在动物生产中的研究与应用", 《贵州畜牧兽医》, vol. 38, no. 6, pages 3 * |
| 赵学峰等: "酸化剂在猪生产中的应用", 《中国动物保健》, vol. 4, no. 5, pages 299 - 300 * |
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