CN115722436A

CN115722436A - Material ball screening device

Info

Publication number: CN115722436A
Application number: CN202110988683.6A
Authority: CN
Inventors: 蒋析文; 刘霭珊; 郑桑桑; 谢晓成
Original assignee: Guangzhou Da'an Gene Co ltd
Current assignee: Guangzhou Da'an Gene Co ltd
Priority date: 2021-08-26
Filing date: 2021-08-26
Publication date: 2023-03-03
Also published as: WO2023024196A1

Abstract

The application relates to the field of biomedical science and discloses a material ball screening device. The material ball screening device comprises a feeding part, wherein the feeding part is provided with a feeding cavity, and the feeding cavity is provided with a feeding port at the top and a discharging port at the bottom; the screening pipeline is obliquely arranged, the top of the screening pipeline is communicated with a discharge hole of the feeding part, and at least one part of the lower side of the screening pipeline is provided with a screening part; the drying part, throw material portion and screening pipeline and locate in the drying chamber of drying part. This application material ball sieving mechanism realizes the purpose of automatic screening, avoids the material ball to absorb moisture atrophy the problem of gluing the wall.

Description

Material ball screening device

Technical Field

The application relates to the field of biomedical, especially, relate to material ball sieving mechanism.

Background

The biological agent has high requirements on the storage environment during the use process, and the activity of the biological agent is damaged due to high temperature. In the prior art, cold chain transportation and low-temperature storage are usually adopted for keeping alive, but the storage method has the defects of instability, high cost, short shelf life and the like. In order to overcome the defects, a novel technology in the field of freeze-drying is developed, namely a freeze-dried bead technology, the technology has the advantages of accurate quantification, single person and single part, convenience in product use and the like, has no requirement on packaging materials, can be subpackaged into packaging materials such as eight-connecting tubes, centrifuge tubes, microfluidic chips, various biological chip cards, flow tubes, 96-pore plates and the like, and can be stored at normal temperature to realize rapid diagnosis. Because the packaging material is not limited, the capacity can be exerted to the limit of the freeze dryer. However, the freeze-dried beads have disadvantages in production, such as very strict development difficulty, very weak property, easy powder falling, small volume, light weight, and easy friction to generate static electricity; if the freeze-dried beads are contacted with air for a long time and easily absorb moisture and shrink, the requirements on a screening environment and screening equipment are very strict, and screening is usually carried out manually in the market at present, which is one reason why the freeze-dried beads cannot be produced on a large scale in time.

Disclosure of Invention

An object of this application is to provide a material ball sieving mechanism, this application material ball sieving mechanism realize the purpose of automatic screening, avoid the material ball to absorb moisture atrophy the problem of gluing the wall.

For solving the technical problem, a first aspect of the present application provides a material ball screening device, including: the feeding part is provided with a feeding cavity, and the feeding cavity is provided with a feeding port at the top and a discharging port at the bottom; the screening pipeline is obliquely arranged, the top of the screening pipeline is communicated with the discharge hole of the feeding part, and at least one part of the lower side of the screening pipeline is provided with a screening part; the drying part, the portion of throwing the material with the screening pipeline is located in the drying chamber of drying part.

In an embodiment of the first aspect, the apparatus further comprises a vibrating device associated with the screening element and configured to vibrate the screening element.

In an embodiment of the first aspect, the drying device further comprises a recycling pipeline, wherein the recycling pipeline is obliquely arranged and arranged in the drying cavity and located below the screening pipeline, so as to recycle and screen the material balls below the screening element.

In an embodiment of the first aspect, at least a portion of the recovery conduit is provided with a mesh communicating with the drying chamber.

In an embodiment of the first aspect, the dispensing opening of the dispensing part is provided with a sealing cover which is operable to open and close.

In an embodiment of the first aspect, the screening element is detachably connected to the screening conduit.

In an embodiment of the first aspect, the screening element is a screen, the mesh of which is a circular hole.

In an embodiment of the first aspect, further comprising a recovery portion in communication with a lower end of the recovery conduit and for receiving the material balls retrieved from the recovery conduit.

In an embodiment of the first aspect, further comprises a charging portion in communication with the lower end of the screening conduit for receiving pellets of material from the screening conduit.

In an embodiment of the first aspect, inner wall surfaces of the charging part, the screening pipe and the charging part are coated with an antistatic layer.

For prior art, this application embodiment, the sieving mechanism of this application material ball realizes the automatic screening of material ball through setting up screening piece, through having avoided the material ball to absorb moisture atrophy the problem of gluing the wall because of long-time and air contact with the sieving mechanism setting in dry chamber.

Drawings

FIG. 1 is a schematic structural diagram of a material ball screening apparatus according to an embodiment of the present disclosure;

fig. 2 is a schematic structural diagram of a material ball screening device including freeze-dried beads according to an embodiment of the present disclosure.

Detailed Description

The following embodiments of the present application are described by specific examples, and other advantages and effects of the present application will be readily apparent to those skilled in the art from the disclosure of the present application. The present application is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present application. It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.

Embodiments of the present application will be described in detail below with reference to the accompanying drawings so that those skilled in the art to which the present application pertains can easily carry out the present application. The present application may be embodied in many different forms and is not limited to the embodiments described herein.

In order to clearly explain the present application, components that are not related to the description are omitted, and the same reference numerals are given to the same or similar components throughout the specification.

Throughout the specification, when a device is referred to as being "connected" to another device, this includes not only the case of being "directly connected" but also the case of being "indirectly connected" with another element interposed therebetween. In addition, when a device "includes" a certain constituent element, unless otherwise specified, it means that the other constituent element is not excluded, but may be included.

When a device is said to be "on" another device, this may be directly on the other device, but may also be accompanied by other devices in between. When a device is said to be "directly on" another device, there are no other devices in between.

Although the terms first, second, etc. may be used herein to describe various elements in some instances, these elements should not be limited by these terms. These terms are only used to distinguish one element from another. For example, the first interface and the second interface, etc. are described. Also, as used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context indicates otherwise. It will be further understood that the terms "comprises," "comprising," "includes" and/or "including," when used in this specification, specify the presence of stated features, steps, operations, elements, components, items, species, and/or groups, but do not preclude the presence, or addition of one or more other features, steps, operations, elements, components, species, and/or groups thereof. The terms "or" and/or "as used herein are to be construed as inclusive or meaning any one or any combination. Thus, "a, B or C" or "a, B and/or C" means "any of the following: a; b; c; a and B; a and C; b and C; A. b and C ". An exception to this definition will occur only when a combination of elements, functions, steps or operations are inherently mutually exclusive in some way.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the singular forms "a", "an" and "the" include plural forms as long as the words do not expressly indicate a contrary meaning. The terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, regions, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of other features, regions, integers, steps, operations, elements, components, and/or groups thereof.

Terms representing relative spatial terms such as "lower", "upper", and the like may be used to more readily describe one element's relationship to another element as illustrated in the figures. Such terms are intended to include not only the meanings indicated in the drawings, but also other meanings or operations of the device in use. For example, if the device in the figures is turned over, elements described as "below" other elements would then be oriented "above" the other elements. Thus, the exemplary terms "under" and "beneath" all include above and below. The device may be rotated 90 or other angles and the terminology representing relative space is also to be interpreted accordingly.

Although not defined differently, including technical and scientific terms used herein, all terms have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. Terms defined in commonly used dictionaries are to be additionally interpreted as having meanings consistent with those of related art documents and the contents of the present prompts, and must not be excessively interpreted as having ideal or very formulaic meanings unless defined.

The material ball screening device comprises a feeding part, a screening pipeline and a drying part, wherein the feeding part is provided with a feeding cavity, and the feeding cavity is provided with a feeding port at the top and a discharging opening at the bottom; the screening pipeline is obliquely arranged, the top of the screening pipeline is communicated with a discharge hole of the feeding part, and at least one part of the lower side of the screening pipeline is provided with a screening part; the feeding part and the screening pipeline are arranged in a drying cavity of the drying part. The material balls to be packaged in the embodiment are taken as freeze-dried beads, and actually, the material balls can be material balls in other forms.

The first embodiment of the present application will be described with reference to the accompanying drawings, and as shown in fig. 1 and 2, the material ball screening device of the present application comprises a feeding part 1, a screening pipeline 2 and a drying part 3, wherein the feeding part 1 is provided with a feeding cavity 10, and the feeding cavity 10 comprises a feeding port 11 at the top and a discharge port 12 at the bottom. Specifically, a discharge port 12 at the bottom of the charging chamber 10 communicates with the top of the lower screening conduit 2. Screening pipeline 2 sets up from the top slope downwards to help its slant gliding to fall after throwing material chamber 10 entering screening pipeline 2, for example freeze-dried pearl's material ball, screening 21 is equipped with to the downside of screening pipeline 2, and screening 21 can locate screening pipeline 2 downside partly, also can be that the downside is whole. The screen 21 may be a mesh or may be in other forms. The mesh of the screen can be circular holes, and can also be other shapes, all without departing from the scope of protection of the present application. The screening element 21 may be fixedly or detachably connected to the screening conduit 2. The screening pieces with meshes of different sizes can be replaced according to needs by the screening device, and the repeated utilization rate of equipment is improved. The screening member 21 can screen out the freeze-dried beads smaller than a predetermined size from the screening channel 2, thereby ensuring that only freeze-dried beads satisfying the predetermined size pass through the screening channel 2. In addition, the feeding port 11 may further be provided with a sealing cover (not shown in the figure), after the freeze-dried beads are fed into the feeding chamber 10, the feeding port 11 is sealed by the sealing cover, so that air can be isolated from entering the feeding chamber 10, a relatively sealed space is formed in the feeding chamber 10, and the freeze-dried beads are prevented from being shriveled or stuck to the wall due to moisture absorption caused by the continuous entering of humid air in the screening process. In addition, a feeding screen can be arranged between the discharge port 12 at the bottom of the feeding chamber 10 and the top of the screening pipe 2, and the mesh of the screen can be slightly larger than the freeze-dried beads with the preset qualified size, for example, the diameter of the mesh of the screen can be larger than 10% -40% of the preset qualified diameter of the freeze-dried beads, so that the freeze-dried beads with larger size or a plurality of bonded beads can be screened out through the feeding screen.

This application material ball sieving mechanism still includes drying portion 3, and drying portion 3 has dry chamber 30. Specifically, the feeding part 1 and the screening pipeline 2 can be arranged in the drying chamber 30 of the drying part 3, so that the freeze-dried beads are always in a dry environment in the screening process, and the freeze-dried beads are prevented from shrinking or sticking to the wall due to moisture absorption. In some embodiments, at least a portion of the feeding portion 1 is provided with a plurality of meshes communicated with the drying chamber 30, and at least a portion of the screening conduit 2 is also provided with a plurality of meshes communicated with the drying chamber 30, so that dry air can be conveniently introduced into the feeding portion 1 and the screening conduit 2, and more excellent drying efficiency can be achieved.

A recovery pipeline 4 can also be arranged below the screening pipeline 2 of the material ball screening device. In particular, the recovery duct 4 is also arranged obliquely downwards, preferably with the recovery duct 4 arranged parallel to the screening duct 2. The recovery pipeline 4 is used for recovering the freeze-dried beads which are screened to the lower part by the screening piece 21 in the screening pipeline 2. At least a part of recovery pipeline 4 is equipped with a plurality of meshs with dry chamber 30 intercommunication, and this meshs are less than the basic size of freeze-dried pearl, avoid the screening to the freeze-dried pearl of recovery pipeline 4 drops below recovery pipeline 4 again, and recovery pipeline 4 and dry chamber 30 intercommunication can realize more excellent drying efficiency simultaneously.

Furthermore, a loading section 5 can be connected to the lower end of the screening conduit 2. Specifically, the charging portion 5 communicates with the lower end of the sieving conduit 2 for receiving the freeze-dried beads from the sieving conduit 2. Similarly, the lower end of the recovery pipeline 4 can be connected with a recovery part 6, the recovery part 6 is used for receiving the freeze-dried beads from the recovery pipeline 4, and the recovery part 6 is detachably connected, so that the recovered freeze-dried beads can be conveniently cleaned. In some embodiments, the screening apparatus of the present application further comprises a vibrating device (not shown) associated with the screen 21 and capable of causing the screen 21 to vibrate. The vibrating device during operation screening piece 21 produces the vibration of low frequency, can avoid the crowded card of freeze-drying pearl in screening pipeline 2 and lead to the screening to go on smoothly, improves the screening efficiency. The vibrating device may be provided in plural and spaced on the screening member 21 so that each section thereof obtains uniform vibration intensity.

This application sieving mechanism can adopt plastics materials such as PP, PE or PET to at the inner wall surface coating antistatic backing that freeze-drying pearl probably contacted, for example the inner wall surface coating antistatic backing that throws material portion, screening pipeline, recovery duct and portion of feeding has, also can adopt metal material such as stainless steel, through making it possess the function of destaticizing with its ground connection, reduce as far as possible because of the problem such as the freeze-drying pearl glues wall jam because of static reason production.

This application sieving mechanism of material ball realizes the automatic screening of material ball through setting up screening piece, will not conform to the material ball screening of dimensional requirement, through setting up sieving mechanism the problem that the material ball glues the wall because of long-time moisture absorption atrophy has been avoided in dry chamber with the air contact to the material ball.

The above embodiments are merely illustrative of the principles and utilities of the present application and are not intended to limit the application. Any person skilled in the art can modify or change the above-described embodiments without departing from the spirit and scope of the present application. Accordingly, it is intended that all equivalent modifications or changes which may be made by those skilled in the art without departing from the spirit and technical spirit of the present disclosure be covered by the claims of the present application.

Claims

1. A material ball screening device, characterized in that includes:

the feeding part is provided with a feeding cavity, and the feeding cavity is provided with a feeding port at the top and a discharging port at the bottom;

the screening pipeline is obliquely arranged, the top of the screening pipeline is communicated with the discharge hole of the feeding part, and at least one part of the lower side of the screening pipeline is provided with a screening part;

the drying part, the portion of throwing the material with the screening pipeline is located in the drying chamber of drying part.

2. A material ball screening apparatus according to claim 1, further comprising a vibration means associated with the screening element and arranged to cause the screening element to vibrate.

3. The material ball screening device according to claim 1, further comprising a recycling pipeline, wherein the recycling pipeline is obliquely arranged and arranged in the drying cavity and below the screening pipeline, so as to recycle the material balls screened below the screening member.

4. A material ball screening apparatus according to claim 3, wherein at least a portion of the recovery conduit is provided with a mesh communicating with the drying chamber.

5. The material ball screening device of claim 1, wherein the feed opening of the feed portion is provided with a sealing cover which can be opened and closed operatively.

6. The material ball screening device of claim 1, wherein the screen member is removably connected to the screening conduit.

7. The material ball screening device of claim 1, wherein the screening element is a screen, and the mesh of the screen is circular holes.

8. The material ball screening device of claim 3, further comprising a recovery portion in communication with a lower end of the recovery conduit for receiving the material balls retrieved from the recovery conduit.

9. The material ball screening device of claim 1, further comprising a charging portion in communication with a lower end of the screening conduit for receiving material balls from the screening conduit.

10. The material ball screening device according to any one of claims 1 to 9, wherein inner wall surfaces of the charging part, the screening pipe and the charging part are coated with an antistatic layer.