CN115708785A - Herbal wash-free gel and preparation process thereof - Google Patents
Herbal wash-free gel and preparation process thereof Download PDFInfo
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- CN115708785A CN115708785A CN202211438256.1A CN202211438256A CN115708785A CN 115708785 A CN115708785 A CN 115708785A CN 202211438256 A CN202211438256 A CN 202211438256A CN 115708785 A CN115708785 A CN 115708785A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 36
- 238000001879 gelation Methods 0.000 title description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims abstract description 42
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 38
- 241000219304 Portulacaceae Species 0.000 claims abstract description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 37
- 238000003756 stirring Methods 0.000 claims abstract description 33
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims abstract description 22
- 238000002156 mixing Methods 0.000 claims abstract description 21
- 238000001914 filtration Methods 0.000 claims abstract description 19
- 239000008213 purified water Substances 0.000 claims abstract description 19
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 16
- 238000010438 heat treatment Methods 0.000 claims abstract description 12
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000000706 filtrate Substances 0.000 claims abstract description 11
- 230000008961 swelling Effects 0.000 claims abstract description 11
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 10
- 229960001631 carbomer Drugs 0.000 claims abstract description 10
- 241001313857 Bletilla striata Species 0.000 claims abstract description 9
- 238000002791 soaking Methods 0.000 claims abstract description 8
- 241000411851 herbal medicine Species 0.000 claims abstract description 7
- 238000010992 reflux Methods 0.000 claims abstract description 7
- 239000000499 gel Substances 0.000 claims description 57
- 239000000243 solution Substances 0.000 claims description 57
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 239000002994 raw material Substances 0.000 claims description 12
- 238000010790 dilution Methods 0.000 claims description 10
- 239000012895 dilution Substances 0.000 claims description 10
- 238000009777 vacuum freeze-drying Methods 0.000 claims description 10
- 238000005406 washing Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 7
- 238000002390 rotary evaporation Methods 0.000 claims description 5
- 241001313855 Bletilla Species 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 12
- 239000003814 drug Substances 0.000 abstract description 6
- 241000628997 Flos Species 0.000 abstract description 5
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 2
- 239000006049 herbal material Substances 0.000 abstract 2
- 238000007865 diluting Methods 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 229940049638 carbomer homopolymer type c Drugs 0.000 description 8
- 229940043234 carbomer-940 Drugs 0.000 description 8
- 229930002875 chlorophyll Natural products 0.000 description 8
- 235000019804 chlorophyll Nutrition 0.000 description 8
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 8
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- 241000588724 Escherichia coli Species 0.000 description 3
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- 241000191967 Staphylococcus aureus Species 0.000 description 3
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- 230000000694 effects Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 244000242564 Osmanthus fragrans Species 0.000 description 2
- 235000019083 Osmanthus fragrans Nutrition 0.000 description 2
- 235000011399 aloe vera Nutrition 0.000 description 2
- 241001116389 Aloe Species 0.000 description 1
- 244000144927 Aloe barbadensis Species 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 235000010894 Artemisia argyi Nutrition 0.000 description 1
- 241001435059 Artemisia argyi Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000209128 Bambusa Species 0.000 description 1
- 241000054078 Citrus depressa Species 0.000 description 1
- 241000555682 Forsythia x intermedia Species 0.000 description 1
- 241000633855 Litsea pungens Species 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 244000178706 Ornithopus sativus Species 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 235000006484 Paeonia officinalis Nutrition 0.000 description 1
- 241000972672 Phellodendron Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 241000246044 Sophora flavescens Species 0.000 description 1
- 241001149649 Taxus wallichiana var. chinensis Species 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 239000008361 herbal raw material Substances 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The scheme discloses a preparation process of herbal wash-free gel in the technical field of antibacterial disinfection, which comprises the following steps: 1. preparing a herbal material, wherein the herbal material comprises purslane, honeysuckle and bletilla striata tablets, putting the purslane into a n-butyl alcohol solution for cold soaking, and filtering to obtain purslane dregs; mixing herba Portulacae residue, flos Lonicerae and rhizoma Bletillae tablet, extracting with 75% ethanol-water under heating and refluxing, filtering, mixing filtrates, concentrating, and freeze drying to obtain extract; 2. uniformly stirring carbomer and water, carrying out water bath and swelling, adding triethanolamine, uniformly stirring, and adjusting the pH value to 6-7 to obtain a first solution; adding the extract into 75% ethanol-water 8-12 times of the weight of the extract to dissolve the extract to obtain solution B; and mixing the solution A and the solution B, diluting with purified water, and stirring uniformly to obtain the herbal wash-free gel. The application highlights the in-vitro antibacterial advantage of natural herbal medicines, and the prepared washing-free gel has light yellow color close to skin color and few Chinese medicine types while ensuring the antibacterial effect.
Description
Technical Field
The invention belongs to the technical field of antibacterial disinfection, and particularly relates to a herbal wash-free gel and a preparation process thereof.
Background
The washing-free gel enables people to clean hands rapidly at any time and any place without water, soap or towels, the hands can be directly kneaded after the gel is extruded out until the hands are dry, the gel can be volatilized in the process of kneading the hands, and the hands are dry and not sticky after the washing-free gel is used. The common washing-free gel mainly comprises a washing gel compatible with chemical reagents and a washing-free gel of traditional Chinese medicine components, wherein the traditional Chinese medicine washing-free gel is taken as a pure natural source substance, so that the traditional Chinese medicine washing-free gel has less toxic and side effects and is favored by consumers.
However, the current herbal leave-on gel generally has the problems of more raw materials and darker color, for example, the patent with application publication number CN113081928a discloses a plant bacteriostatic gel and a preparation method and application thereof, wherein the raw materials comprise forsythia extract, bletilla striata extract, sophora flavescens extract, peony root extract, honeysuckle extract, phellodendron extract, aloe juice, essential oil and the like; also for example, patent publication No. CN111658595A discloses a method for preparing natural plant small molecular group cell sap for use in disposable gel products, which comprises, as raw materials, taxus chinensis branch and leaf cell sap, mulberry leaf, cacumen Platycladi, litsea pungens, artemisia argyi leaf, citrus depressa, osmanthus fragrans, ecliptae herba, bambusa branch and leaf, flos Chrysanthemi Indici, bark of young bird's foot, osmanthus fragrans leaf and fruit, cell sap extracted from folium Pelargonii Graveolentis, aloe Barbadensis extract, carbomer, and argentum solution. The large amount of raw materials increases the difficulty of obtaining the raw materials; in addition, the traditional Chinese medicine is generally darker and contains more chlorophyll, so that the traditional Chinese medicine extract is darker, the prepared wash-free gel is darker, and the skin color and the appearance are influenced.
Disclosure of Invention
The invention aims to provide a preparation process of herbal wash-free gel, so as to reduce raw materials and reduce the color depth of the wash-free gel.
The preparation process of the herbal wash-free gel comprises the following steps:
the method comprises the following steps of preparing a herbal medicine, wherein the herbal medicine comprises the following raw materials in parts by weight: 2 to 4 portions of purslane, 1 to 2 portions of honeysuckle and 0.5 to 1.5 portions of common bletilla tuber tablets; placing purslane into n-butanol solution for cold soaking for 20-30 h, and then filtering to obtain purslane dregs; then mixing the purslane herb residues, the honeysuckle and the bletilla striata tablets, performing heating reflux extraction for 2-3 times by using 75% ethanol-water, wherein each time lasts for 1.5-2.5 h, then filtering, combining the filtrates, performing rotary evaporation, recovering, concentrating, and performing vacuum freeze drying to obtain an extract;
step two, uniformly stirring carbomer and water according to the weight ratio of 1 to 65-75, carrying out water bath at the temperature of 45-55 ℃ for 15-25 min, adding triethanolamine after swelling, uniformly stirring, and adjusting the pH value to 6-7 to obtain a solution A; then taking the extract with the same weight as carbomer, adding the extract into 75% ethanol-water with the weight of 8-12 times of that of the extract to dissolve the extract to obtain solution B; and mixing the solution A and the solution B, adding purified water with the weight being 20 times that of carbomer for dilution, and uniformly stirring to obtain the herbal wash-free gel.
The beneficial effect of this scheme: according to the scheme, only purslane, honeysuckle and bletilla striata tablets are selected as herbal raw materials, and the weight ratio of the purslane, the honeysuckle and the bletilla striata tablets is set to be 2-4: 1 to 2: 0.5-1.5, and during preparation, 75% ethanol-water is used for heating reflux extraction of the herbs, so that antibacterial ingredients in the raw materials overflow, and the prepared wash-free gel is ensured to have good antibacterial effect. In addition, the purslane is soaked in the n-butyl alcohol solution, so that a large amount of chlorophyll in the purslane is lost, and the honeysuckle and the bletilla striata tablets are lighter in color, so that the prepared wash-free gel is lighter in color depth close to skin color, easy to accept, free of trace and better in appearance.
Further, in the first step, before the purslane herb residue is mixed with the honeysuckle and the bletilla striata tablets, 75% ethanol is used for washing the purslane herb residue. Residual n-butanol and chlorophyll on the purslane dregs are further washed away by washing.
Further, the Chinese herbal medicine comprises the following raw materials in parts by weight: 3 parts of purslane, 1.5 parts of honeysuckle and 0.5-1.5 parts of rhizoma bletillae tablets. The washing-free gel prepared by adopting the proportion has better antibacterial effect.
Further, in the second step, the weight ratio of the carbomer to the water is 1.
Based on the selection of raw materials and the improvement of a preparation process, the herbal leave-on gel prepared by the application has a good antibacterial effect, and particularly has a good inhibition effect on pseudomonas aeruginosa, candida albicans, staphylococcus aureus and escherichia coli. The herbal wash-free gel prepared by the preparation process is also within the protection scope of the application.
Drawings
Fig. 1 is a display diagram of the herbal leave-on gel prepared in example 1 of the present invention after bottling.
Detailed Description
Example 1:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 60g of dried purslane medicinal material into 600g of n-butyl alcohol solution for cold soaking for 24h, filtering, taking purslane residue, and washing the residue with 75% ethanol to remove residual n-butyl alcohol and chlorophyll on the purslane residue;
placing herba Portulacae residue, flos Lonicerae 30g, and rhizoma Bletillae tablet 20g into a flask, heating and reflux-extracting with 1100g of 75% ethanol-water for 2 times, each time for 2 hr, filtering, mixing the two filtrates, rotary-steaming, recovering, concentrating, and vacuum freeze-drying to obtain extract.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, performing water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain yellowish transparent herbal wash-free gel (shown in figure 1).
Comparative example 1:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 60g of dried purslane medicinal material into 600g of n-butyl alcohol solution for cold soaking for 24h, filtering, taking purslane residue, and washing the residue with 75% ethanol to remove residual n-butyl alcohol and chlorophyll on the purslane residue;
placing herba Portulacae residue into a flask, heating and reflux-extracting with 600g of 75% ethanol-water for 2 times, each time for 2 hr, filtering, mixing the two filtrates, rotary-steaming, recovering, concentrating, and vacuum freeze-drying to obtain extract.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 2:
a herbal wash-free gel and a preparation process thereof comprise the following steps:
step one, preparation of extracting solution
Placing 30g of honeysuckle into a flask, heating and refluxing with 300g of 75% ethanol-water for 2 times, each time for 2 hours, filtering, combining the two filtrates, recovering and concentrating by rotary evaporation, and performing vacuum freeze drying to obtain an extract for later use.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 3:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 20g of rhizoma bletilla tablet into a flask, heating and refluxing with 200g of 75% ethanol-water for 2 times, each time for 2h, filtering, mixing the two filtrates, performing rotary evaporation, recovering and concentrating, and vacuum freeze drying to obtain extract for use.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 4:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 60g of dried purslane medicinal material into 600g of n-butyl alcohol solution for cold soaking for 24h, filtering, taking purslane residue, and washing the residue with 75% ethanol to remove residual n-butyl alcohol and chlorophyll on the purslane residue;
placing herba Portulacae residue and flos Lonicerae 30g into flask, heating and reflux-extracting with 75% ethanol-water 900g for 2 times, each for 2 hr, filtering, mixing the filtrates, rotary-steaming, recovering, concentrating, and vacuum freeze-drying to obtain extract.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 5:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 60g of dried purslane medicinal material into 600g of n-butyl alcohol solution for cold soaking for 24h, filtering, taking purslane residue, and washing the residue with 75% ethanol to remove residual n-butyl alcohol and chlorophyll on the purslane residue;
placing herba Portulacae residue and rhizoma Bletillae tablet 20g into a flask, heating and reflux-extracting with 800g of 75% ethanol-water for 2 times, each time for 2 hr, filtering, mixing the two filtrates, rotary-steaming, recovering, concentrating, and vacuum freeze-drying to obtain extract.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 6:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Putting 30g of honeysuckle and 20g of rhizoma bletillae tablets into a flask, heating and refluxing with 500g of 75% ethanol-water for 2 times, each time for 2 hours, filtering, combining the two filtrates, performing rotary evaporation, recovering, concentrating, and performing vacuum freeze drying to obtain an extract for later use.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Comparative example 7:
a preparation process of herbal wash-free gel comprises the following steps:
step one, preparation of extracting solution
Placing 60g of dried purslane medicinal material into 600g of n-butyl alcohol solution for cold soaking for 24h, filtering, taking purslane residue, and washing the residue with 75% ethanol to remove residual n-butyl alcohol and chlorophyll on the purslane residue;
placing herba Portulacae residue, 30g flos Lonicerae and 20g rhizoma Bletillae tablet into a flask, heating and reflux-extracting with 1100g water for 2 times, each for 2 hr, filtering, mixing the two filtrates, rotary-steaming, recovering, concentrating, and vacuum freeze-drying to obtain extract.
Step two, preparation of gel
Taking 1g of carbomer 940, adding 70g of purified water, stirring, carrying out water bath at 50 ℃ for 20min, adding triethanolamine after swelling, stirring uniformly, and adjusting pH to 6-7 to obtain solution A; dissolving another 1g extract in 10g 75% ethanol-water to obtain solution B, mixing solution A and solution B, adding 20g purified water for dilution, and stirring to obtain herbal wash-free gel.
Three antibacterial parallel experiments were performed using the herbal leave-on gels prepared in example 1 and comparative examples 1 to 7 and a 75% ethanol solution, each experiment group was used at 0.1ml, the bacteria were selected from escherichia coli, staphylococcus aureus, candida albicans and pseudomonas aeruginosa, and the results were recorded as follows (data is rounded to leave one decimal place):
antibacterial experiments prove that: the purslane, the honeysuckle and the bletilla have obvious antibacterial effect on escherichia coli, staphylococcus aureus, candida albicans and pseudomonas aeruginosa after being combined, and the antibacterial effect is better than that of single use or combined use of two components.
The foregoing is merely an example of the present invention and common general knowledge of known specific structures and features of the embodiments is not described herein in any greater detail. It should be noted that, for those skilled in the art, without departing from the structure of the present invention, several changes and modifications can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.
Claims (5)
1. A preparation process of herbal wash-free gel is characterized by comprising the following steps: the method comprises the following steps:
the method comprises the following steps of preparing a herbal medicine, wherein the herbal medicine comprises the following raw materials in parts by weight: 2 to 4 portions of purslane, 1 to 2 portions of honeysuckle and 0.5 to 1.5 portions of common bletilla tuber tablets; placing purslane into n-butanol solution for cold soaking for 20-30 h, and then filtering to obtain purslane dregs; then mixing the purslane herb residues, the honeysuckle and the bletilla striata tablets, performing heating reflux extraction for 2-3 times by using 75% ethanol-water, wherein each time lasts for 1.5-2.5 h, then filtering, combining the filtrates, performing rotary evaporation, recovering, concentrating, and performing vacuum freeze drying to obtain an extract;
step two, uniformly stirring carbomer and water according to the weight ratio of 1 to 65-75, carrying out water bath at the temperature of 45-55 ℃ for 15-25 min, adding triethanolamine after swelling, uniformly stirring, and adjusting the pH value to 6-7 to obtain a liquid A; then taking the extract with the same weight as carbomer, adding the extract into 75% ethanol-water with the weight of 8-12 times of that of the extract to dissolve the extract to obtain solution B; and mixing the solution A and the solution B, adding purified water with the weight being 20 times that of carbomer for dilution, and uniformly stirring to obtain the herbal wash-free gel.
2. The process of claim 1 for preparing a herbal leave-on gel, wherein: in the first step, before the purslane herb residues are mixed with the honeysuckle and the bletilla striata tablets, 75% ethanol is used for washing the purslane herb residues.
3. The process for preparing a herbal leave-on gel according to claim 2, wherein: the Chinese herbal medicine comprises the following raw materials in parts by weight: 3 parts of purslane, 1.5 parts of honeysuckle and 0.5-1.5 parts of rhizoma bletillae tablets.
4. The process for preparing a herbal leave-on gel according to claim 3, wherein: in the second step, the weight ratio of the carbomer to the water is 1.
5. A herbal wash-free gel is characterized in that: prepared by the process of preparation of herbal leave-on gels as claimed in any one of claims 1 to 4.
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579822A (en) * | 2012-02-04 | 2012-07-18 | 高玉英 | Antimicrobial and production method thereof |
| WO2017051950A1 (en) * | 2015-09-24 | 2017-03-30 | 노병승 | Method for manufacturing oriental medicinal soap for improving atopic dermatitis |
| CN107550818A (en) * | 2017-09-26 | 2018-01-09 | 广西达庆生物科技股份有限公司 | A kind of washing-free antibacterial liquid and preparation method thereof |
| CN107929335A (en) * | 2017-12-11 | 2018-04-20 | 安徽坤大生物工程技术有限公司 | A kind of extraction processing technology of purslane |
| CN109512851A (en) * | 2018-12-28 | 2019-03-26 | 惠州卫生职业技术学院 | Medical antibacterial midwifery gel of one kind and preparation method thereof |
| CN113081928A (en) * | 2021-04-29 | 2021-07-09 | 云南赛森生物科技有限公司 | Plant bacteriostatic gel and preparation method and application thereof |
| CN113116775A (en) * | 2021-04-07 | 2021-07-16 | 山东药品食品职业学院 | Acne-removing gel mask and preparation process thereof |
-
2022
- 2022-11-16 CN CN202211438256.1A patent/CN115708785B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579822A (en) * | 2012-02-04 | 2012-07-18 | 高玉英 | Antimicrobial and production method thereof |
| WO2017051950A1 (en) * | 2015-09-24 | 2017-03-30 | 노병승 | Method for manufacturing oriental medicinal soap for improving atopic dermatitis |
| CN107550818A (en) * | 2017-09-26 | 2018-01-09 | 广西达庆生物科技股份有限公司 | A kind of washing-free antibacterial liquid and preparation method thereof |
| CN107929335A (en) * | 2017-12-11 | 2018-04-20 | 安徽坤大生物工程技术有限公司 | A kind of extraction processing technology of purslane |
| CN109512851A (en) * | 2018-12-28 | 2019-03-26 | 惠州卫生职业技术学院 | Medical antibacterial midwifery gel of one kind and preparation method thereof |
| CN113116775A (en) * | 2021-04-07 | 2021-07-16 | 山东药品食品职业学院 | Acne-removing gel mask and preparation process thereof |
| CN113081928A (en) * | 2021-04-29 | 2021-07-09 | 云南赛森生物科技有限公司 | Plant bacteriostatic gel and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 宋红光: "天然药物化学理论与研究方法", vol. 1, 西北农林科学技术大学出版社, pages: 258 * |
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