CN110876705A - Hand sanitizer and preparation method thereof - Google Patents

Hand sanitizer and preparation method thereof Download PDF

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CN110876705A
CN110876705A CN201911141146.7A CN201911141146A CN110876705A CN 110876705 A CN110876705 A CN 110876705A CN 201911141146 A CN201911141146 A CN 201911141146A CN 110876705 A CN110876705 A CN 110876705A
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parts
stirring
soap base
hand sanitizer
extracting solution
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高林岗
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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Abstract

The invention provides a hand sanitizer which comprises the following raw materials in parts by mass: 10-20 parts of kojic acid, 120 parts of soap base 100-containing materials, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extracts, 35-45 parts of plant extracts, 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride, 2-4 parts of camphor tree leaf extracting solution and 300 parts of deionized water 100-containing materials.

Description

Hand sanitizer and preparation method thereof
Technical Field
The invention belongs to the technical field of daily chemical articles, relates to a hand sanitizer, and further relates to a preparation method of the hand sanitizer.
Background
As a novel hand cleaning product, the hand sanitizer appears late compared with traditional cleaning products such as perfumed soap, soap and the like, but the hand sanitizer is popular with more and more consumers because of the characteristics of convenient use, time and water conservation, avoidance of cross infection, easy storage, reduction of natural consumption and the like. Along with the improvement of the requirements of people on living quality, the requirements on the product performance of the hand sanitizer are increased, the cleanliness of the hand sanitizer needs to be ensured, a certain health care effect needs to be achieved, skin irritation is avoided, and chemical additives are few. Some existing products have few functions, some bactericides adopt chemical products, and some bactericides are added with preservatives and the like. Thus, as the consumer market for hand sanitizers matures, there is a need for a hand sanitizer that is versatile and mild.
Disclosure of Invention
The invention aims to provide a hand sanitizer, and solves the problem that the hand sanitizer in the prior art is not ideal in sterilization and decontamination effects.
The invention also aims to provide a preparation method of the hand sanitizer, which solves the problems of complex process and difficult operation of the hand sanitizer preparation in the prior art.
The technical scheme adopted by the invention is that,
the hand sanitizer comprises the following raw materials in parts by mass: 10-20 parts of kojic acid, 120 parts of soap base 100-containing materials, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extracts, 35-45 parts of plant extracts, 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride, 2-4 parts of camphor tree leaf extracting solution and 300 parts of deionized water 100-containing materials.
Yet another feature of the present invention is that,
the soap base comprises the following components in percentage by weight: 2: 3 palm oil soap base, coconut oil soap base and tea seed oil soap base.
The traditional Chinese medicine extract comprises extracts of weeping forsythia leaves, baical skullcap roots, astragalus roots, cochinchnese asparagus roots, yam flour, white paeony roots, largehead atractylodes rhizomes and white poria cocos in equal weight ratio.
The plant extracts comprise licorice, mint, aloe and olive extracts in equal weight ratio.
A preparation method of a hand sanitizer comprises the following steps:
step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
step 2, weighing the weeping forsythia leaves according to equal weight ratioPulverizing Scutellariae radix, radix astragali, radix asparagi, rhizoma Dioscoreae powder, radix Paeoniae alba, Atractylodis rhizoma and Poria, sieving with 60-80 mesh sieve, and subjecting folium forsythiae, Scutellariae radix, radix astragali, radix asparagi, rhizoma Dioscoreae powder, radix Paeoniae alba, Atractylodis rhizoma and Poria powder to supercritical CO treatment at 40 deg.C and 10-20MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 60-70 ℃, decocting for 1.5-2.5h, then merging decoction and filtering, adding filtrate to ethanol solution for soaking, then carrying out ultrasonic-microwave assisted extraction, and carrying out vacuum freeze drying on the extracted filtrate to obtain plant extract;
step 4, respectively weighing 10-20 parts of kojic acid, 120 parts of soap base 100-25 parts, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extract, 35-45 parts of plant extract and 300 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 70-80 ℃, cooling to 25-35 ℃ after stirring for 30-40min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 30-40min to obtain a mixed solution A.
Step 5, respectively weighing 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride and 2-4 parts of camphor tree leaf extracting solution according to mass fraction;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 5-10min at the temperature of 70-80 ℃ to prepare a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 80-90 ℃, and continuously stirring for 3-5min to obtain mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 90-100 ℃, and continuously stirring for 3-5min to obtain the hand sanitizer.
The invention has the beneficial effects that: kojic acid is used as a raw material and is added into the hand sanitizer, so that the effects of whitening, removing speckles, inhibiting bacteria and killing bacteria can be achieved while daily hand washing is carried out, and the hand sanitizer plays an extremely positive role in preventing diseases from entering the mouth. The hand sanitizer is matched with various Chinese herbal medicine plant extracts, the use of chemical synthetic bactericides and preservatives is reduced, and the hand sanitizer is milder, does not hurt hands and moistens hands
Detailed Description
The present invention will be described in detail with reference to the following embodiments.
The invention provides a hand sanitizer which comprises the following raw materials in parts by mass: 10-20 parts of kojic acid, 120 parts of soap base 100-containing materials, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extracts, 35-45 parts of plant extracts, 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride, 2-4 parts of camphor tree leaf extracting solution and 300 parts of deionized water 100-containing materials.
The soap base comprises the following components in percentage by weight: 2: 3 palm oil soap base, coconut oil soap base and tea seed oil soap base. The traditional Chinese medicine extract comprises extracts of weeping forsythia leaves, baical skullcap roots, astragalus roots, cochinchnese asparagus roots, yam flour, white paeony roots, largehead atractylodes rhizomes and white poria cocos in equal weight ratio. The plant extracts comprise licorice, mint, aloe and olive extracts in equal weight ratio.
The invention also provides a preparation method of the hand sanitizer, which comprises the following steps:
step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
step 2, weighing weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, white paeony root, bighead atractylodes rhizome and white poria cocos according to equal weight proportion, crushing, sieving by a 60-80-mesh sieve, and performing supercritical CO treatment on weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos powder under the conditions that the temperature is 40 ℃ and the pressure is 10-20MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 60-70 ℃, decocting for 1.5-2.5h, then merging decoction and filtering, adding filtrate to ethanol solution for soaking, then carrying out ultrasonic-microwave assisted extraction, and carrying out vacuum freeze drying on the extracted filtrate to obtain plant extract;
step 4, respectively weighing 10-20 parts of kojic acid, 120 parts of soap base 100-25 parts, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extract, 35-45 parts of plant extract and 300 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 70-80 ℃, cooling to 25-35 ℃ after stirring for 30-40min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 30-40min to obtain a mixed solution A.
Step 5, respectively weighing 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride and 2-4 parts of camphor tree leaf extracting solution according to mass fraction;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 5-10min at the temperature of 70-80 ℃ to prepare a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 80-90 ℃, and continuously stirring for 3-5min to obtain mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 90-100 ℃, and continuously stirring for 3-5min to obtain the hand sanitizer.
Example 1
Step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
in the step 2, the step of mixing the raw materials,weighing folium forsythiae, Scutellariae radix, radix astragali, radix asparagi, rhizoma Dioscoreae powder, radix Paeoniae alba, Atractylodis rhizoma and Poria according to equal weight ratio, pulverizing, sieving with 60 mesh sieve, and subjecting folium forsythiae, Scutellariae radix, radix astragali, radix asparagi, rhizoma Dioscoreae powder, radix Paeoniae alba, Atractylodis rhizoma and Poria powder to supercritical CO treatment at 40 deg.C and 10MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 60 ℃, decocting for 1.5h, then combining decoction and filtering, adding filtrate to ethanol solution for soaking, then performing ultrasonic-microwave assisted extraction, and performing vacuum freeze drying on the extraction filtrate to obtain plant extract;
step 4, weighing 10 parts of kojic acid, 100 parts of soap base, 40 parts of fatty acid polyoxyethylene ether sodium sulfate, 10 parts of dodecyl dimethyl betaine, 15 parts of coconut oil fatty acid diethanolamide, 35 parts of traditional Chinese medicine extract, 35 parts of plant extract and 100 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 70 ℃, cooling to 25 ℃ after stirring for 30min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 30min to obtain a mixed solution A.
Step 5, respectively weighing 40 parts of cocamidopropyl betaine, 35 parts of sorbitol, 25 parts of glycerol, 10 parts of citric acid, 10 parts of chrysanthemum extract, 2 parts of thickening agent, 10 parts of sodium chloride and 2 parts of camphor tree leaf extract according to mass fractions;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 5min at the temperature of 70 ℃ to prepare a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 80 ℃, and continuously stirring for 3min to obtain a mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 90 ℃, and continuously stirring for 3min to obtain the hand sanitizer.
Example 2
Step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
step 2, weighing weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos according to equal weight proportion, crushing, sieving by a 80-mesh sieve, and performing supercritical CO treatment on the weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos powder at the temperature of 40 ℃ and the pressure of 20MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 70 ℃, decocting for 2.5h, mixing decoction, filtering, adding filtrate to ethanol solution for soaking, then performing ultrasonic-microwave assisted extraction, and performing vacuum freeze drying on the extraction filtrate to obtain plant extract;
step 4, respectively weighing 20 parts of kojic acid, 120 parts of soap base, 50 parts of fatty acid polyoxyethylene ether sodium sulfate, 30 parts of dodecyl dimethyl betaine, 25 parts of coconut oil fatty acid diethanolamide, 45 parts of traditional Chinese medicine extract, 45 parts of plant extract and 300 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 80 ℃, cooling to 35 ℃ after stirring for 40min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 40min to obtain a mixed solution A.
Step 5, respectively weighing 46 parts of cocamidopropyl betaine, 38 parts of sorbitol, 30 parts of glycerol, 20 parts of citric acid, 20 parts of chrysanthemum extract, 4 parts of thickening agent, 12 parts of sodium chloride and 4 parts of camphor tree leaf extract according to mass fractions;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 10min at the temperature of 80 ℃ to obtain a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 90 ℃, and continuously stirring for 5min to obtain a mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 100 ℃, and continuously stirring for 5min to obtain the hand sanitizer.
Example 3
Step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
step 2, weighing weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos according to equal weight proportion, crushing, sieving with a 70-mesh sieve, and performing supercritical CO treatment on the weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos powder under the conditions that the temperature is 40 ℃ and the pressure is 15MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 65 ℃, decocting for 2.0h, mixing decoction, filtering, adding filtrate to ethanol solution to soak, then performing ultrasonic-microwave assisted extraction, and performing vacuum freeze drying on the extraction filtrate to obtain plant extract;
step 4, weighing 15 parts of kojic acid, 110 parts of soap base, 45 parts of fatty acid polyoxyethylene ether sodium sulfate, 20 parts of dodecyl dimethyl betaine, 20 parts of coconut oil fatty acid diethanolamide, 40 parts of traditional Chinese medicine extract, 40 parts of plant extract and 200 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 70-80 ℃, cooling to 30 ℃ after stirring for 35min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 35min to obtain a mixed solution A.
Step 5, respectively weighing 43 parts of cocamidopropyl betaine, 36.5 parts of sorbitol, 27 parts of glycerol, 15 parts of citric acid, 15 parts of chrysanthemum extract, 3 parts of thickening agent, 11 parts of sodium chloride and 3 parts of camphor tree leaf extract according to mass fractions;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 7min at the temperature of 75 ℃ to obtain a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 85 ℃, and continuously stirring for 4min to obtain mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 95 ℃, and continuously stirring for 4min to obtain the hand sanitizer.

Claims (5)

1. The hand sanitizer is characterized by comprising the following raw materials in parts by mass: 10-20 parts of kojic acid, 120 parts of soap base 100-containing materials, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extracts, 35-45 parts of plant extracts, 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride, 2-4 parts of camphor tree leaf extracting solution and 300 parts of deionized water 100-containing materials.
2. The hand sanitizer of claim 1, wherein the soap base comprises, by weight, 1: 2: 3 palm oil soap base, coconut oil soap base and tea seed oil soap base.
3. The hand sanitizer according to claim 1 or 2, wherein the Chinese medicine extracts comprise extracts of weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and poria alba in equal weight ratio.
4. The hand sanitizer according to claim 3, wherein the plant extracts comprise equal proportions by weight of licorice, mint, aloe, and olive extracts.
5. The preparation method of the hand sanitizer is characterized by comprising the following steps:
step 1, mixing the raw materials in a weight ratio of 1: 2: 3, weighing palm oil soap base, coconut oil soap base and tea seed oil soap base, dissolving and stirring the materials uniformly at 90 ℃, and then cooling the materials to normal temperature to obtain soap base;
step 2, weighing weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, white paeony root, bighead atractylodes rhizome and white poria cocos according to equal weight proportion, crushing, sieving by a 60-80-mesh sieve, and performing supercritical CO treatment on weeping forsythia leaves, scutellaria baicalensis, astragalus mongholicus, radix asparagi, yam flour, radix paeoniae alba, bighead atractylodes rhizome and white poria cocos powder under the conditions that the temperature is 40 ℃ and the pressure is 10-20MPa2Extracting to obtain Chinese medicinal extract;
step 3, weighing liquorice, mint, aloe and olive according to equal weight ratio, respectively adding deionized water to soak for 30min at 60-70 ℃, decocting for 1.5-2.5h, then merging decoction and filtering, adding filtrate to ethanol solution for soaking, then carrying out ultrasonic-microwave assisted extraction, and carrying out vacuum freeze drying on the extracted filtrate to obtain plant extract;
step 4, respectively weighing 10-20 parts of kojic acid, 120 parts of soap base 100-25 parts, 40-50 parts of fatty acid polyoxyethylene ether sodium sulfate, 10-30 parts of dodecyl dimethyl betaine, 15-25 parts of coconut oil fatty acid diethanolamide, 35-45 parts of traditional Chinese medicine extract, 35-45 parts of plant extract and 300 parts of deionized water according to mass fraction, mixing and uniformly stirring at the temperature of 70-80 ℃, cooling to 25-35 ℃ after stirring for 30-40min, adding kojic acid, the traditional Chinese medicine extract and the plant extract, mixing and uniformly stirring, and stirring for 30-40min to obtain a mixed solution A.
Step 5, respectively weighing 40-46 parts of cocamidopropyl betaine, 35-38 parts of sorbitol, 25-30 parts of glycerol, 10-20 parts of citric acid, 10-20 parts of chrysanthemum extracting solution, 2-4 parts of thickening agent, 10-12 parts of sodium chloride and 2-4 parts of camphor tree leaf extracting solution according to mass fraction;
step 6, feeding the cocamidopropyl betaine, the sorbitol, the glycerol and the citric acid weighed in the step 5 into a stirring device, and stirring for 5-10min at the temperature of 70-80 ℃ to prepare a mixed solution B;
step 7, adding the chrysanthemum extracting solution, the sodium chloride and the camphor tree leaf extracting solution weighed in the step 5 into the mixed solution B, heating to 80-90 ℃, and continuously stirring for 3-5min to obtain mixed solution C;
and 8, uniformly mixing and stirring the mixed liquor A and the mixed liquor C, adding the thickening agent weighed in the step 5, heating to 90-100 ℃, and continuously stirring for 3-5min to obtain the hand sanitizer.
CN201911141146.7A 2019-11-20 2019-11-20 Hand sanitizer and preparation method thereof Pending CN110876705A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494390A (en) * 2020-12-21 2021-03-16 安徽亿人安股份有限公司 Water-locking and moisture-preserving type antibacterial hand sanitizer
CN112852566A (en) * 2021-01-19 2021-05-28 北京圣永制药有限公司 A bacteriostatic soap containing Chinese medicinal components
CN114712281A (en) * 2022-04-07 2022-07-08 扬州大学 Supercritical CO2Extracted plant extract and its preparation method and application

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CN108514533A (en) * 2018-05-14 2018-09-11 成都金开生物工程有限公司 Kojic acid bacteriostatic hand sanitizer and preparation method thereof
CN109157463A (en) * 2018-11-24 2019-01-08 四川月天抗菌制剂有限公司 A kind of chrysanthemum hand cleanser and preparation method thereof

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN108514533A (en) * 2018-05-14 2018-09-11 成都金开生物工程有限公司 Kojic acid bacteriostatic hand sanitizer and preparation method thereof
CN109157463A (en) * 2018-11-24 2019-01-08 四川月天抗菌制剂有限公司 A kind of chrysanthemum hand cleanser and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494390A (en) * 2020-12-21 2021-03-16 安徽亿人安股份有限公司 Water-locking and moisture-preserving type antibacterial hand sanitizer
CN112852566A (en) * 2021-01-19 2021-05-28 北京圣永制药有限公司 A bacteriostatic soap containing Chinese medicinal components
CN114712281A (en) * 2022-04-07 2022-07-08 扬州大学 Supercritical CO2Extracted plant extract and its preparation method and application
CN114712281B (en) * 2022-04-07 2023-12-08 扬州大学 Supercritical CO 2 Extracted plant extract and preparation method and application thereof

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Application publication date: 20200313