CN115671540A - In vivo implantation assembly of pudendal nerve stimulation system and pudendal nerve stimulation system - Google Patents
In vivo implantation assembly of pudendal nerve stimulation system and pudendal nerve stimulation system Download PDFInfo
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Abstract
An in vivo implantation assembly of a pudendal nerve stimulation system comprises a first stimulation unit (10), a second stimulation unit (20), an implantation wireless communication module (30), an implantation control unit (40) and a power supply unit (50). The first stimulation unit is capable of receiving the signal and stimulating the pudendal nerve via the first stimulation electrode (12) to cause contraction of the detrusor and sphincter muscles. The second stimulation unit is capable of receiving the signal and stimulating the pudendal nerve via a second stimulation electrode (22) to block sphincter contractions. The implantation control unit can establish wireless communication with other equipment through implantation wireless communication module, and output signals to the first stimulation unit and the second stimulation unit according to the received control signal. The power supply unit can store electrical energy and provide it to the implanted control unit. The in-vivo implanted component enables the pudendal nerve stimulation system to stimulate the pudendal nerve with standard parameters and procedures to realize urination. The invention also relates to a pudendal nerve stimulation system comprising the in-vivo implanted component.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an in-vivo implanted component of a pudendum nerve stimulation system and the pudendum nerve stimulation system comprising the in-vivo implanted component.
Background
After spinal cord injury, detrusor sphincter dyssynergia can occur, patients cannot urinate autonomously, and bladder high pressure, urine retention and other problems are easy to occur. The commonly used sacral nerve stimulator needs to excise the posterior sacral nerve root, which can affect other functions of the patient. At present, urination can be realized by means of stimulating pudendal nerves by electrodes, but the stimulation intensity, frequency and time can only be obtained by experience, and standard parameters do not guide the stimulation.
Disclosure of Invention
The invention aims to provide an in-vivo implanted component of a pudendal nerve stimulation system, which can stimulate the pudendal nerve to realize urination by standard parameters and procedures and is more convenient to use.
Another object of the present invention is to provide a pudendal nerve stimulation system, which can stimulate pudendal nerve with standard parameters and procedures to achieve urination, and is more convenient to use.
The present invention provides an in vivo implant assembly for a pudendal nerve stimulation system, the implant assembly being capable of being implanted adjacent to a bladder within a human body. The intracorporeal implantation assembly includes a first stimulation unit, a second stimulation unit, an implantation wireless communication module, an implantation control unit and a power supply unit. The first stimulation unit comprises a first stimulation electrode, the first stimulation electrode can be arranged on the pudendal nerve, the first stimulation unit can receive a first stimulation pulse signal and process the first stimulation pulse signal, and then the first stimulation electrode stimulates the pudendal nerve to cause contraction of the detrusor muscle and the sphincter muscle. The second stimulation unit comprises a second stimulation electrode, the second stimulation electrode can be arranged on the pudendal nerve, the second stimulation unit can receive and process a second stimulation pulse signal, and then the pudendal nerve is stimulated through the second stimulation electrode so as to block the contraction of the sphincter muscle and cause the relaxation of the sphincter muscle. The implanted wireless communication module is used for establishing wireless communication. The implantation control unit is connected with the first stimulation unit, the second stimulation unit and the implantation wireless communication module, and the implantation control unit is configured to be capable of establishing wireless communication with other equipment through the implantation wireless communication module and outputting a first stimulation pulse signal and a second stimulation pulse signal to the first stimulation unit and the second stimulation unit according to a received control signal. The power supply unit is capable of storing electrical energy and providing it to the implanted control unit.
The implanted control unit can establish wireless communication with other equipment through the implanted wireless communication module, inputs a first stimulation pulse signal and a second stimulation pulse signal to the first stimulation unit and the second stimulation unit when receiving a control signal, stimulates the pudendal nerve through the first stimulation electrode and the second stimulation electrode, keeps the relaxation of the sphincter muscle, and causes the contraction of detrusor muscle to realize the function of micturition. The in-vivo implanted component can enable the pudendum nerve stimulation system to stimulate the pudendum nerve with standard parameters and procedures to realize urination, and is more convenient to use.
In another exemplary embodiment of an interbody implant assembly of a pudendal nerve stimulation system, the interbody implant assembly further includes a first measurement unit and a second measurement unit. The first measuring unit comprises a first measuring electrode, the first measuring electrode can be arranged on a detrusor, and the first measuring unit can acquire and process an electromyographic signal of the detrusor through the first measuring electrode. The second measuring unit comprises a second measuring electrode, the second measuring electrode is arranged on the sphincter, and the second measuring unit can collect and process the electromyographic signals of the sphincter through the second measuring electrode. The implantation control unit is connected with the first measuring unit and the second measuring unit and receives the processed myoelectric signals of the detrusor and the sphincter, and the implantation control unit is also configured to send out the processed myoelectric signals of the detrusor and the sphincter through the established wireless communication. Thereby, the states of the detrusor muscle and the sphincter can be obtained at any time.
In another exemplary embodiment of the in vivo implant assembly of a pudendal nerve stimulation system, the first measurement unit further includes a first signal conditioning circuit and a first analog-to-digital conversion circuit. The first signal conditioning circuit can condition the myoelectric signals of the detrusor muscle acquired by the first measuring electrode, and the conditioning mode comprises amplification, low-pass filtering, high-pass filtering and power frequency interference. The first analog-to-digital conversion circuit can perform analog-to-digital conversion on the conditioned myoelectric signal of the detrusor and output the myoelectric signal to the implantation control unit. The second measurement unit further comprises a second signal conditioning circuit and a second analog-to-digital conversion circuit. The second signal conditioning circuit can condition the sphincter electromyographic signals collected by the second measuring electrode, and the conditioning mode comprises amplification, low-pass filtering, high-pass filtering and power frequency interference removal. The second analog-to-digital conversion circuit can perform analog-to-digital conversion on the sphincter electromyographic signals conditioned by the second signal conditioning circuit and output the sphincter electromyographic signals to the implantation control unit.
In another exemplary embodiment of the in vivo implanted component of the pudendal nerve stimulation system, the first stimulation unit further includes a first digital-to-analog conversion circuit, a first voltage-to-current conversion circuit, and a first charge balancing circuit. The first digital-to-analog conversion circuit can perform digital-to-analog conversion on the first stimulation pulse signal output by the implanted control unit. The first voltage-current conversion circuit can receive the first stimulation pulse signal converted by the first digital-to-analog conversion circuit and convert the first stimulation pulse signal into a constant current electrical signal. The first charge balance circuit can receive the first stimulation pulse signal converted by the first voltage-current conversion circuit and balance charges, so that the charge quantity of a positive phase current and a reverse phase current of the first stimulation pulse signal is the same. The second stimulation unit further comprises a second digital-to-analog conversion circuit, a second voltage-to-current conversion circuit and a second charge balance circuit. The second digital-to-analog conversion circuit can perform digital-to-analog conversion on the second stimulation pulse signal output by the implanted control unit. The second voltage-current conversion circuit can receive the second stimulation pulse signal converted by the second digital-analog conversion circuit and convert the second stimulation pulse signal into a constant current signal. The second charge balance circuit can receive the second stimulation pulse signal converted by the second voltage-current conversion circuit and balance the charges, so that the charge quantity of the positive phase current and the charge quantity of the reverse phase current of the second stimulation pulse signal are the same.
In another exemplary embodiment of the implantable assembly of the pudendal nerve stimulation system, the first stimulation unit further includes a first measurement feedback circuit, which is capable of receiving the first stimulation pulse signal after the first charge balance circuit performs charge balance and monitoring in real time, and controlling the implantation control unit to adjust the output first stimulation pulse signal when the monitored parameter of the first stimulation pulse signal is deviated. The second stimulation unit also comprises a second measurement feedback circuit which can receive the second stimulation pulse signal after the second charge balance circuit carries out charge balance and monitor the second stimulation pulse signal in real time, and the second stimulation pulse signal which is output by the implant control unit is controlled to be adjusted when the parameter of the second stimulation pulse signal is monitored to have deviation. Therefore, closed-loop control over the first stimulation pulse signal and the second stimulation pulse signal can be formed, and the accuracy of the first stimulation pulse signal and the second stimulation pulse signal is ensured.
In another exemplary embodiment of the in vivo implanted component of the pudendal nerve stimulation system, the in vivo implanted component comprises two second stimulation units, and two second stimulation electrodes of the two second stimulation units are respectively arranged on two side branches of the pudendal nerve. Thereby blocking sphincter contractions more effectively.
In another exemplary embodiment of an implantable assembly for a pudendal nerve stimulation system, a power supply unit includes an implantable coupling coil, a resonant circuit, and a rectifying energy storage module. The implanted coupling coil is used for receiving electromagnetic waves generated by other devices in the environment. The resonant circuit can form magnetic coupling resonance with electromagnetic waves in the environment through the implanted coupling coil and generate electric energy. The rectification energy storage module can rectify and store the electric energy generated by the resonant circuit. Whereby the power supply unit can be replenished with electric power in a wireless manner.
The invention also provides a pudendal nerve stimulation system which comprises the in-vivo implanted component and an out-of-body controller. The external controller comprises an external wireless communication module and an external control unit. The in-vitro wireless communication module is used for establishing wireless communication. The extracorporeal control unit is configured to be able to establish communication with the implant control unit via the extracorporeal wireless communication module and the implant wireless communication module and to send a control signal to the implant control unit.
The pudendal nerve stimulation system provided by the invention is provided with an in-vivo implanted component which can be implanted near a bladder in a human body, the implanted control unit can establish wireless communication with the in-vitro control unit through the implanted wireless communication module and the in-vitro wireless communication module, and when a control signal sent by the in-vitro control unit is received, a first stimulation pulse signal and a second stimulation pulse signal are input to the first stimulation unit and the second stimulation unit, the pudendal nerve is stimulated through the first stimulation electrode and the second stimulation electrode, the contraction of a detrusor muscle is caused while the relaxation of the sphincter muscle is kept, and the urination function is realized. The pudendum nerve stimulation system can stimulate pudendum nerve with standard parameters and procedures to realize urination, and is more convenient to use.
In another exemplary embodiment of the pudendal nerve stimulation system, the in vivo implant assembly further comprises: a first measuring unit and a second measuring unit. The first measuring unit comprises a first measuring electrode, the first measuring electrode can be arranged on a detrusor, and the first measuring unit can acquire an electromyographic signal of the detrusor through the first measuring electrode and process the electromyographic signal. The second measuring unit comprises a second measuring electrode, the second measuring electrode is arranged on the sphincter, and the second measuring unit can acquire and process the electromyographic signals of the sphincter through the second measuring electrode. The implantation control unit is connected with the first measuring unit and the second measuring unit and receives the processed myoelectric signals of the detrusor and the sphincter, and the implantation control unit is also configured to send out the processed myoelectric signals of the detrusor and the sphincter through the established wireless communication. The external controller also comprises a display unit, and the external controller is also configured to receive the myoelectric signals of the detrusor and the sphincter sent by the implanted control unit and control the display unit to display. Therefore, the states of the detrusor muscle and the sphincter can be obtained at any time in vitro.
In another exemplary embodiment of the pudendal nerve stimulation system, the power supply unit includes an implanted coupling coil, a resonant circuit, and a rectifying energy storage module. The implanted coupling coil is used for receiving electromagnetic waves generated by other devices in the environment. The resonant circuit can form magnetic coupling resonance with electromagnetic waves in the environment through the implanted coupling coil and generate electric energy. The rectification energy storage module can rectify and store the electric energy generated by the resonant circuit. The extracorporeal controller further comprises an extracorporeal coupling coil, and the extracorporeal control unit is further configured to control the extracorporeal coupling coil to generate electromagnetic waves that the implanted coupling coil can receive. Whereby the power supply unit can be supplied with electric power in a wireless manner.
Drawings
The following drawings are only schematic illustrations and explanations of the present invention, and do not limit the scope of the present invention.
FIG. 1 is a schematic diagram illustrating one exemplary embodiment of an interbody implant assembly for a pudendal nerve stimulation system.
Fig. 2 is a schematic diagram illustrating a specific use of the in vivo implant assembly for pudendal nerve stimulation system.
FIG. 3 is a schematic diagram illustrating another exemplary embodiment of an interbody implant assembly for a pudendal nerve stimulation system.
Description of the reference symbols
10. First stimulation unit
11. Non-traumatic cuff
12. First stimulating electrode
14. A first digital-to-analog conversion circuit
15. First voltage-current conversion circuit
16. A first charge balance circuit
18. First measurement feedback circuit
20. Second stimulation unit
21. Non-traumatic cuff
22. Second stimulating electrode
24. Second D/A converter circuit
25. Second voltage-current conversion circuit
26. Second charge balance circuit
28. Second measurement feedback circuit
30. Implanted wireless communication module
40. Implant control unit
50. Power supply unit
52. Implanted coupling coil
54. Resonant circuit
56. Rectification energy storage module
60. First measuring unit
62. A first measuring electrode
64. First signal conditioning circuit
66. First analog-to-digital conversion circuit
70. Second measuring unit
72. Second measuring electrode
74. Second signal conditioning circuit
76. Second analog-to-digital conversion circuit
80. External controller
82. External wireless communication module
84. Extracorporeal control unit
86. Display unit
88. In vitro coupling coil
92. Detrusor muscle
94. Sphincter muscle
96. The pudendal nerve.
Detailed Description
In order to more clearly understand the technical features, objects and effects of the present invention, embodiments of the present invention will now be described with reference to the accompanying drawings, in which the same reference numerals indicate the same or structurally similar but functionally identical elements.
"exemplary" means "serving as an example, instance, or illustration" herein, and any illustration, embodiment, or steps described as "exemplary" herein should not be construed as a preferred or advantageous alternative.
FIG. 1 is a schematic diagram illustrating one exemplary embodiment of an interbody implant assembly for a pudendal nerve stimulation system. Referring to fig. 1, the implant assembly can be implanted in a human body in the vicinity of a bladder. The intracorporeal implant assembly comprises one first stimulation unit 10, two second stimulation units 20, one implant wireless communication module 30, one implant control unit 40 and one power supply unit 50.
Fig. 2 is a schematic diagram illustrating a specific use of the in vivo implant assembly for pudendal nerve stimulation system. Referring to fig. 1 and 2, the first stimulation unit 10 includes a first stimulation electrode 12, the first stimulation electrode 12 can be disposed on a branch of the pudendal nerve 96 through a non-traumatic cuff (cuff) 11 sleeved on the pudendal nerve 96, the first stimulation unit 10 can receive a first stimulation pulse signal and process the first stimulation pulse signal, and the first stimulation electrode 12 stimulates the pudendal nerve 96 to cause contraction of the detrusor muscle 92 and the sphincter muscle 94.
Referring to fig. 1 and 2, each of the second stimulation units 20 includes one second stimulation electrode 22, the second stimulation electrode 22 is capable of being disposed on a branch of the pudendal nerve 96 by passing through a non-traumatic cuff (cuff) 21 disposed on the pudendal nerve 96, and the two second stimulation electrodes 22 are disposed on two side branches of the pudendal nerve 96, respectively. Each second stimulation unit 20 is capable of receiving and processing a second stimulation pulse signal to stimulate the pudendal nerve 96 via the second stimulation electrode 22 to block contraction of the sphincter muscle 94 and cause relaxation of the sphincter muscle 94. Although two second stimulation units 20 are included in the exemplary embodiment to more effectively block the contraction of the sphincter 94, it is not limited thereto, and only one second stimulation unit 20 may be included in other exemplary embodiments.
The wireless communication module 30 is implanted for establishing wireless communication. The implant control unit 40 is connected to the first stimulation unit 10, the second stimulation unit 20 and the implant wireless communication module 30, and the implant control unit 40 is configured to establish wireless communication with other devices through the implant wireless communication module 30 and output the first stimulation pulse signal and the second stimulation pulse signal to the first stimulation unit 10 and the second stimulation unit 20 according to the received one control signal. The control signal can determine the output and stop of the first stimulation pulse signal and the second stimulation pulse signal, and can adjust parameters of the first stimulation pulse signal and the second stimulation pulse signal. Power supply unit 50 is capable of storing electrical energy and providing it to implanted control unit 40.
The in-vivo implantation component of the pudendal nerve stimulation system can be implanted near a bladder in a human body, an implantation control unit 40 can establish wireless communication with other devices through an implantation wireless communication module 30, and when receiving a control signal, inputs a first stimulation pulse signal and a second stimulation pulse signal to a first stimulation unit 10 and a second stimulation unit 20, stimulates the pudendal nerve 96 through a first stimulation electrode 12 and a second stimulation electrode 22, and achieves a urination function by causing contraction of a detrusor 92 while keeping relaxation of a sphincter 94. The in-vivo implanted component can enable the pudendum nerve stimulation system to stimulate the pudendum nerve with standard parameters and procedures to realize urination, and is more convenient to use.
In the illustrated embodiment, the implanted wireless communication module 30 is a bluetooth low energy module. Therefore, energy consumption can be saved, and endurance can be improved. However, without being limited thereto, in other exemplary embodiments, implanted wireless communication module 30 may also be other types of communication modules, such as a WIFI module.
In an exemplary embodiment, referring to fig. 1, the first stimulation unit 10 further includes a first digital-to-analog conversion circuit 14, a first voltage-to-current conversion circuit 15, and a first charge balancing circuit 16. The first digital-to-analog conversion circuit 14 can perform digital-to-analog conversion on the first stimulation pulse signal output by the implanted control unit 40. The first voltage-current conversion circuit 15 can receive the first stimulation pulse signal converted by the first digital-to-analog conversion circuit 14 and convert the first stimulation pulse signal into a constant current electrical signal. The first charge balance circuit 16 is capable of receiving the first stimulation pulse signal converted by the first voltage/current conversion circuit 15 and performing charge balance such that the charge amount of the positive phase current and the charge amount of the negative phase current of the first stimulation pulse signal are the same. Thereby avoiding the accumulation of unbalanced charge at the first stimulation electrode 12 over time, reducing the risk of corrosion and damage to the nerve.
In an exemplary embodiment, referring to fig. 1, each second stimulation unit 20 further includes a second digital-to-analog conversion circuit 24, a second voltage-to-current conversion circuit 25, and a second charge balancing circuit 26. The second digital-to-analog conversion circuit 24 can perform digital-to-analog conversion on the second stimulation pulse signal output by the implant control unit 40. The second voltage-current conversion circuit 25 can receive the second stimulation pulse signal converted by the second digital-to-analog conversion circuit 24 and convert the second stimulation pulse signal into a constant current signal. The second charge balance circuit 26 can receive the second stimulation pulse signal converted by the second voltage-to-current conversion circuit 25 and perform charge balance so that the charge amount of the positive phase current and the charge amount of the negative phase current of the second stimulation pulse signal are the same. Thereby avoiding the accumulation of unbalanced charge at the second stimulation electrode 22 over time, reducing the risk of corrosion and damage to the nerve.
In an exemplary embodiment, referring to fig. 1, the intracorporeal implant set further includes a first measuring unit 60 and a second measuring unit 70.
The first measurement unit 60 includes a first measurement electrode 62, a first signal conditioning circuit 64, and a first analog-to-digital conversion circuit 66. The first measuring electrode 62 can be disposed at the detrusor 92, and the first measuring unit 60 can collect the electromyographic signals of the detrusor 92 through the first measuring electrode 62. The first signal conditioning circuit 64 can condition the electromyographic signals of the detrusor muscle 92 acquired by the first measuring electrode 62, and the conditioning modes comprise amplification, low-pass filtering, high-pass filtering and power frequency interference. The first analog-to-digital conversion circuit 66 can perform analog-to-digital conversion on the conditioned myoelectric signal of the detrusor muscle 92 of the first signal conditioning circuit 64 and output the myoelectric signal to the implantation control unit 40.
The second measurement cell 70 includes a second measurement electrode 72, a second signal conditioning circuit 74, and a second analog-to-digital conversion circuit 76. The second measuring electrode 72 is provided to the sphincter 94, and the second measuring unit 70 can collect the electromyographic signal of the sphincter 94 through the second measuring electrode 72. The second signal conditioning circuit 74 can condition the electromyographic signals of the sphincter 94 acquired by the second measuring electrode 72 by means of amplification, low-pass filtering, high-pass filtering and power frequency interference elimination. The second analog-to-digital conversion circuit 76 can perform analog-to-digital conversion on the myoelectric signal of the sphincter 94 conditioned by the second signal conditioning circuit 74 and output the myoelectric signal to the implantation control unit 40
The implant control unit 40 is connected to the first and second measurement units 60 and 70, and receives the processed electromyographic signals of the detrusor muscle 92 and the sphincter muscle 94. The electromyographic signals of the detrusor 92 and the sphincter 94 can indicate the current status of the detrusor 92 and the sphincter 94, whereby the implanted control unit 40 can more intelligently adjust the first and second stimulation pulse signals depending on the current status of the detrusor 92 and the sphincter 94. Meanwhile, the implanted control unit 40 is also configured to be able to send out the processed myoelectric signals of the detrusor muscle 92 and the myoelectric signals of the sphincter muscle 94 through the established wireless communication. The state of the detrusor 92 and sphincter 94 can thereby be obtained at any time outside the body.
FIG. 3 is a schematic diagram illustrating another exemplary embodiment of an interbody implant assembly for a pudendal nerve stimulation system. Referring to fig. 3, the same or similar parts as those of the in-vivo implant component in fig. 1 are not repeated, but the first stimulation unit 10 further includes a first measurement feedback circuit 18, which is capable of receiving the first stimulation pulse signal after the first charge balancing circuit 16 performs charge balancing and monitoring in real time, and controlling the implant control unit 40 to adjust the output first stimulation pulse signal when the monitored parameter of the first stimulation pulse signal is deviated. The second stimulation unit 20 further includes a second measurement feedback circuit 28, which is capable of receiving the second stimulation pulse signal after the charge balancing circuit 26 performs charge balancing, monitoring the second stimulation pulse signal in real time, and controlling the implanted control unit 40 to adjust the output second stimulation pulse signal when a deviation of a parameter of the second stimulation pulse signal is monitored. Therefore, closed-loop control over the first stimulation pulse signal and the second stimulation pulse signal can be formed, and the accuracy of the first stimulation pulse signal and the second stimulation pulse signal is ensured.
In the illustrated embodiment, and referring to fig. 3, the power supply unit 50 includes an implanted coupling coil 52, a resonant circuit 54, and a rectifying energy storage module 56. The implanted coupling coil 52 is used to receive electromagnetic waves generated by other devices in the environment. The resonant circuit 54 is capable of forming magnetic coupling resonance with electromagnetic waves in the environment by implanting the coupling coil 52 and generating electrical energy. The rectified energy storage module 56 is capable of rectifying and storing the electrical energy generated by the resonant circuit 54. Whereby the power supply unit 50 can be replenished with electric power in a wireless manner.
The present invention also provides a pudendal nerve stimulation system, and referring to fig. 1, the pudendal nerve stimulation system includes an intracorporeal implant assembly as described above and an extracorporeal controller 80. The extracorporeal controller 80 includes an extracorporeal wireless communication module 82 and an extracorporeal control unit 84. The extracorporeal wireless communication module 82 is a bluetooth low energy module and is used to establish wireless communication. The extracorporeal control unit 84 is configured to be able to establish communication with the implanted control unit 40 via the extracorporeal wireless communication module 82 and the implanted wireless communication module 30 and to send control signals to the implanted control unit 40.
The pudendal nerve stimulation system provided by the invention is provided with an internal implanted component which can be implanted in the vicinity of a bladder in a human body, an implanted control unit 40 can establish wireless communication with an external control unit 84 through an implanted wireless communication module 30 and an external wireless communication module 82, and when receiving a control signal sent by the external control unit 84, inputs a first stimulation pulse signal and a second stimulation pulse signal to a first stimulation unit 10 and a second stimulation unit 20, stimulates a pudendal nerve 96 through a first stimulation electrode 12 and a second stimulation electrode 22, keeps the relaxation of a sphincter muscle 94, and causes the contraction of a detrusor 92 at the same time of keeping the relaxation of the sphincter muscle 94, thereby realizing the urination function. The pudendal nerve stimulation system can stimulate pudendal nerves to realize urination by standard parameters and procedures, and is more convenient to use.
In another exemplary embodiment, referring to FIG. 3, the extracorporeal controller 80 further includes a display unit 86, and the extracorporeal control unit 84 is further configured to receive the myoelectric signal of the detrusor 92 and the myoelectric signal of the sphincter 94 from the implanted control unit 40 and control the display unit 86 to display. The state of the detrusor muscle 92 and the sphincter muscle 94 can thereby be obtained at any time outside the body.
In another exemplary embodiment, referring to fig. 3, the extracorporeal control unit 84 is further configured to control the extracorporeal coupling coil 88 to generate electromagnetic waves that the implanted coupling coil 52 can receive. Whereby the power supply unit 50 can be replenished with electric power in a wireless manner.
It should be understood that although the present description has been described in terms of various embodiments, not every embodiment includes only a single embodiment, and such description is for clarity purposes only, and those skilled in the art will recognize that the embodiments described herein may be combined as suitable to form other embodiments, as will be appreciated by those skilled in the art.
The above-listed detailed description is only a specific description of possible embodiments of the present invention, and they are not intended to limit the scope of the present invention, and equivalent embodiments or modifications such as combinations, divisions, or repetitions of features, which do not depart from the technical spirit of the present invention, should be included in the scope of the present invention.
Claims (10)
1. An intracorporeal implant assembly for a pudendal nerve stimulation system, said implant assembly being capable of being implanted within a human body in the vicinity of a bladder, said intracorporeal implant assembly comprising:
a first stimulation unit (10) including a first stimulation electrode (12), said first stimulation electrode (12) being adapted to be positioned in the pudendal nerve, said first stimulation unit (10) being adapted to receive a first stimulation pulse signal and process it to stimulate the pudendal nerve via said first stimulation electrode (12) to cause contraction of the detrusor and sphincter muscles;
a second stimulation unit (20) comprising a second stimulation electrode (22), wherein the second stimulation electrode (22) can be arranged on the pudendal nerve, and the second stimulation unit (20) can receive a second stimulation pulse signal and process the second stimulation pulse signal, and then stimulate the pudendal nerve through the second stimulation electrode (22) to block the contraction of the sphincter muscle and cause the relaxation of the sphincter muscle;
an implanted wireless communication module (30) for establishing wireless communication;
an implanted control unit (40) connected to the first stimulation unit (10), the second stimulation unit (20) and the implanted wireless communication module (30), the implanted control unit (40) being configured to be capable of establishing wireless communication with other devices via the implanted wireless communication module (30) and to output the first and second stimulation pulse signals to the first and second stimulation units (10, 20) in accordance with a received control signal; and
a power supply unit (50) capable of storing electrical energy and providing it to the implanted control unit (40).
2. The interbody implant assembly of claim 1, further comprising:
a first measuring unit (60) comprising a first measuring electrode (62), said first measuring electrode (62) being capable of being arranged in the detrusor muscle, said first measuring unit (60) being capable of acquiring and processing electromyographic signals of the detrusor muscle via said first measuring electrode (62), and
a second measuring unit (70) comprising a second measuring electrode (72), wherein the second measuring electrode (72) is arranged on the sphincter muscle, and the second measuring unit (70) can collect and process the electromyographic signals of the sphincter muscle through the second measuring electrode (72);
the implantation control unit (40) is connected with the first measurement unit (60) and the second measurement unit (70) and receives the processed myoelectric signals of the detrusor muscle and the sphincter muscle, and the implantation control unit (40) is further configured to send out the processed myoelectric signals of the detrusor muscle and the sphincter muscle through the established wireless communication.
3. The interbody implant assembly of claim 2,
the first measurement unit (60) further comprises:
a first signal conditioning circuit (64) capable of conditioning the electromyographic signals of the detrusor muscle collected by the first measurement electrode (62) by amplification, low pass filtering, high pass filtering, and power frequency interference, and
a first analog-to-digital conversion circuit (66) which can perform analog-to-digital conversion on the conditioned myoelectric signal of the detrusor muscle by the first signal conditioning circuit (64) and output the myoelectric signal to the implantation control unit (40);
the second measuring unit (70) further comprises:
a second signal conditioning circuit (74) capable of conditioning the electromyographic signals of the sphincter acquired by said second measuring electrode (72) by amplification, low-pass filtering, high-pass filtering and interference elimination, and
a second analog-to-digital conversion circuit (76) capable of analog-to-digital converting the sphincter muscle electrical signal conditioned by the second signal conditioning circuit (74) and outputting the converted sphincter muscle electrical signal to the implanted control unit (40).
4. The interbody implant assembly of claim 1, wherein,
the first stimulation unit (10) further comprises:
a first digital-to-analog conversion circuit (14) capable of digital-to-analog converting the first stimulation pulse signal output by the implanted control unit (40),
a first voltage-current conversion circuit (15) capable of receiving the first stimulation pulse signal converted by the first digital-to-analog conversion circuit (14) and converting the first stimulation pulse signal into a constant current electrical signal, and
a first charge balance circuit (16) which is capable of receiving the first stimulation pulse signal converted by the first voltage-to-current conversion circuit (15) and performing charge balance so that the charge amount of a positive phase current and a reverse phase current of the first stimulation pulse signal is the same;
the second stimulation unit (20) further comprises:
a second digital-to-analog conversion circuit (24) capable of digital-to-analog converting the second stimulation pulse signal output by the implanted control unit (40),
a second voltage-current conversion circuit (25) capable of receiving the second stimulation pulse signal converted by the second digital-analog conversion circuit (24) and converting it into a constant current signal, and
and a second charge balance circuit (26) which is capable of receiving the second stimulation pulse signal converted by the second voltage-to-current conversion circuit (25) and performing charge balance so that the charge amount of the positive phase current and the charge amount of the negative phase current of the second stimulation pulse signal are the same.
5. The interbody implant assembly of claim 4,
the first stimulation unit (10) further comprises a first measurement feedback circuit (18) which can receive the first stimulation pulse signal after the first charge balance circuit (16) performs charge balance and monitor the first stimulation pulse signal in real time, and control the implantation control unit (40) to adjust the output of the first stimulation pulse signal when the deviation of the parameter of the first stimulation pulse signal is monitored;
the second stimulation unit (20) further comprises a second measurement feedback circuit (28) which is capable of receiving the second stimulation pulse signal after the second charge balance circuit (26) performs charge balance and monitoring in real time, and controlling the implantation control unit (40) to adjust the output of the second stimulation pulse signal when the deviation of the parameter of the second stimulation pulse signal is monitored.
6. The in vivo implant assembly as recited in claim 1, further characterized in that said in vivo implant assembly comprises two of said second stimulation units (20), and two of said second stimulation electrodes (22) of two of said second stimulation units (20) are respectively disposed on two side branches of pudendal nerve.
7. The interbody implant assembly of pudendal nerve stimulation system of claim 1, wherein said power supply unit (50) includes:
an implanted coupling coil (52) for receiving electromagnetic waves generated by other devices in the environment,
a resonant circuit (54) capable of forming magnetic coupling resonance with electromagnetic waves in the environment through the implanted coupling coil (52) and generating electrical energy, an
A rectifying energy storage module (56) capable of rectifying and storing the electrical energy generated by the resonant circuit (54).
8. Pudendal nerve stimulation system characterized in that includes:
an intracorporeal implant assembly of any one of claims 1-7; and
an off-board controller (80) comprising:
an extracorporeal wireless communication module (82) for establishing wireless communication; and
an extracorporeal control unit (84) configured to establish communication with the implanted control unit (40) via the extracorporeal wireless communication module (82) and the implanted wireless communication module (30) and to send the control signal to the implanted control unit (40).
9. The pudendal nerve stimulation system of claim 8,
the intracorporeal implant assembly further comprises:
a first measuring unit (60) comprising a first measuring electrode (62), said first measuring electrode (62) being arranged to the detrusor muscle, said first measuring unit (60) being capable of acquiring and processing electromyographic signals of the detrusor muscle via said first measuring electrode (62), and
a second measuring unit (70) including a second measuring electrode (72), wherein the second measuring electrode (72) is disposed on the sphincter, and the second measuring unit (70) can collect and process the myoelectric signal of the sphincter through the second measuring electrode (72);
the implantation control unit (40) is connected with the first measurement unit (60) and the second measurement unit (70) and receives the processed myoelectric signals of the detrusor muscle and the myoelectric signals of the sphincter muscle, and the implantation control unit (40) is also configured to send out the processed myoelectric signals of the detrusor muscle and the myoelectric signals of the sphincter muscle through established wireless communication;
the external controller (80) further comprises a display unit (86), and the external control unit (84) is further configured to receive the myoelectric signals of the detrusor muscle and the sphincter muscle from the implanted control unit (40) and control the display unit (86) to display.
10. The pudendal nerve stimulation system of claim 8,
the power supply unit (50) includes:
an implanted coupling coil (52) for receiving electromagnetic waves generated by other devices in the environment,
a resonant circuit (54) capable of forming magnetic coupling resonance with electromagnetic waves in the environment through the implanted coupling coil (52) and generating electrical energy, an
A rectifying energy storage module (56) capable of rectifying and storing the electric energy generated by the resonant circuit (54);
the extracorporeal controller (80) further comprises an extracorporeal coupling coil (88), and the extracorporeal control unit (84) is further configured to control the extracorporeal coupling coil (88) to generate electromagnetic waves that the implant coupling coil (52) can receive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210798944.2A CN115671540A (en) | 2022-07-08 | 2022-07-08 | In vivo implantation assembly of pudendal nerve stimulation system and pudendal nerve stimulation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210798944.2A CN115671540A (en) | 2022-07-08 | 2022-07-08 | In vivo implantation assembly of pudendal nerve stimulation system and pudendal nerve stimulation system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115671540A true CN115671540A (en) | 2023-02-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210798944.2A Pending CN115671540A (en) | 2022-07-08 | 2022-07-08 | In vivo implantation assembly of pudendal nerve stimulation system and pudendal nerve stimulation system |
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| Country | Link |
|---|---|
| CN (1) | CN115671540A (en) |
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