CN115624593A - Plaster for treating wound and preparation method thereof - Google Patents
Plaster for treating wound and preparation method thereof Download PDFInfo
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- CN115624593A CN115624593A CN202210490808.7A CN202210490808A CN115624593A CN 115624593 A CN115624593 A CN 115624593A CN 202210490808 A CN202210490808 A CN 202210490808A CN 115624593 A CN115624593 A CN 115624593A
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- 239000011505 plaster Substances 0.000 title claims abstract description 60
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 229940099259 vaseline Drugs 0.000 claims abstract description 33
- 239000000843 powder Substances 0.000 claims abstract description 21
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 19
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 19
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims abstract description 19
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 19
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 19
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims abstract description 19
- 235000008282 Sanguisorba officinalis Nutrition 0.000 claims abstract description 19
- 229940116229 borneol Drugs 0.000 claims abstract description 19
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229940105847 calamine Drugs 0.000 claims abstract description 19
- 229910052956 cinnabar Inorganic materials 0.000 claims abstract description 19
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229910052864 hemimorphite Inorganic materials 0.000 claims abstract description 19
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000011787 zinc oxide Substances 0.000 claims abstract description 19
- 235000014692 zinc oxide Nutrition 0.000 claims abstract description 19
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 claims abstract description 19
- 241001180876 Saposhnikovia Species 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 241000213006 Angelica dahurica Species 0.000 claims abstract description 15
- 238000002156 mixing Methods 0.000 claims abstract description 14
- 238000005303 weighing Methods 0.000 claims abstract description 14
- 238000010438 heat treatment Methods 0.000 claims abstract description 11
- 241001313857 Bletilla striata Species 0.000 claims abstract description 10
- 238000001816 cooling Methods 0.000 claims abstract description 10
- 238000000227 grinding Methods 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims abstract description 7
- 229940043266 rosin Drugs 0.000 claims abstract description 3
- 241000581682 Sanguisorba Species 0.000 claims description 15
- 241001313855 Bletilla Species 0.000 claims description 9
- 241000125175 Angelica Species 0.000 claims description 4
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 4
- 206010052428 Wound Diseases 0.000 abstract description 27
- 208000027418 Wounds and injury Diseases 0.000 abstract description 27
- 230000000694 effects Effects 0.000 abstract description 8
- 206010053615 Thermal burn Diseases 0.000 abstract description 5
- 235000008291 Poterium sanguisorba Nutrition 0.000 abstract description 3
- 239000003610 charcoal Substances 0.000 abstract description 3
- 240000004064 Poterium sanguisorba Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 description 17
- 230000035876 healing Effects 0.000 description 12
- 210000003491 skin Anatomy 0.000 description 9
- 238000009472 formulation Methods 0.000 description 8
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 210000002683 foot Anatomy 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 208000035874 Excoriation Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 244000173853 Sanguisorba officinalis Species 0.000 description 2
- 206010072170 Skin wound Diseases 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010016326 Feeling cold Diseases 0.000 description 1
- 241000229179 Ledebouriella Species 0.000 description 1
- 206010034016 Paronychia Diseases 0.000 description 1
- 241000029132 Paronychia Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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- Pain & Pain Management (AREA)
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Abstract
The invention provides a plaster for treating wounds and a preparation method thereof, wherein the plaster comprises the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla striata, 1.3-1.6 parts of garden burnet charcoal, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline, and the preparation method comprises the following specific steps of S1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, garden burnet charcoal, divaricate saposhnikovia root and Chinese angelica according to the parts by weight, mixing and grinding to form medicinal powder for later use; s2, weighing vaseline in parts by weight, and heating; and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound. The plaster can effectively relieve the pain of patients with wounds, can be used for patients with different degrees of wounds, helps the skin of the patients to heal quickly, and has good effect on the patients with different degrees of burns and scalds.
Description
Technical Field
The invention relates to the technical field of plaster, in particular to a plaster for treating wounds and a preparation method thereof.
Background
The skin is the tissue of the body surface wrapped outside the muscle, is the largest organ of the human body surface area, and mainly plays the roles of protecting the body, discharging sweat, feeling cold and heat, pressure and the like. The skin covers the whole body and protects various tissues and organs in the body from physical, mechanical, chemical and pathogenic microbial attacks. In daily life, skin injuries of different degrees are easily caused due to external and self factors, skin tissues can be separated or damaged after skin wounds, although the skin has certain self-healing capacity, the skin wounds such as burns and scalds which are not closed up due to old wounds and the skin diseases such as paronychia, tinea pedis, cracking of hands and feet and abrasion need to be treated by medicine intervention, the most commonly used medicine for the skin diseases with the symptoms is the external plaster, but the current external plaster on the market has complex prescription, complicated preparation process and insufficient skin repairing effect.
Disclosure of Invention
In order to solve the problems, the invention adopts the following technical scheme: a plaster for treating wounds is prepared from the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla, 1.3-1.6 parts of carbonized sanguisorba root, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla striata, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root, 0.45 part of angelica and 40 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla striata, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root, 0.4 part of Chinese angelica and 45 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 1.5 parts of calamine, 0.6 part of borneol, 1.1 parts of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla striata, 1.45 parts of carbonized sanguisorba root, 1.1 parts of divaricate saposhnikovia root, 0.6 part of angelica and 60 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root, 0.5 part of Chinese angelica and 50 parts of vaseline.
A preparation method of a plaster for treating wound comprises the following specific steps:
s1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, carbonized sanguisorba root, divaricate saposhnikovia root and Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use;
s2, weighing vaseline in parts by weight, and heating;
and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
The beneficial effects of the invention are as follows: the plaster can effectively relieve the pain of patients with wounds, can be used for patients with different degrees of wounds, helps the skin of the patients to heal quickly, and has good effect on the patients with different degrees of burns and scalds.
Detailed Description
The technical solution of the present invention will be further described below, and the present invention is not limited to the following specific embodiments. It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
Specifically, the calamine can be used for astringing dampness, relieving itching and healing sore, and is used for treating unhealed ulcer, dribbling pus and skin itch, the borneol is used for treating sore and swollen pain and unhealed ulcer, the rosin is used for dispelling wind and drying dampness, expelling pus and drawing out pus and promoting granulation and relieving pain, the cinnabar is used for clearing heat and detoxicating and sore and ulcer pyogenic infections, the pseudo-ginseng is used for dissipating blood stasis and stopping bleeding, and relieving swelling and stopping pain, and the bletilla is used for astringing to stop bleeding and relieving swelling and promoting granulation, the sanguisorba officinalis is used for treating blood heat and bleeding, detoxifying and healing sore, burns, eczema and skin ulcer, the ledebouriella root is used for dispelling wind and eliminating dampness, relieving pain and preventing tetanus, and the angelica is used for enriching blood, activating blood and regulating menstruation and relieving pain.
Example 1:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root and 0.45 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 40 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the freshly heated Vaseline, is manually stirred, is directly kept stand and cooled after being uniformly stirred, and is finally cooled to room temperature to obtain the plaster.
Example 2:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root and 0.4 part of Chinese angelica according to the parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 45 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Example 3:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 1.5 parts of calamine, 0.6 part of borneol, 1.1 part of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla, 1.45 parts of garden burnet charcoal, 1.1 parts of divaricate saposhnikovia root and 0.6 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 60 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Example 4:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root and 0.5 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
S2, weighing 50 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Plaster clinical experiment 1:
60 patients with the same degree of bruise were randomly selected and divided into 6 groups, the first group was externally applied with the plaster of the formulation of example 1 of the present invention, the second group was externally applied with the plaster of the formulation of example 2 of the present invention, the third group was externally applied with the plaster of the formulation of example 3 of the present invention, the fourth group was externally applied with the plaster of the formulation of example 4 of the present invention, the fifth group was externally applied with the existing plaster, and the sixth group was externally applied with normal saline.
Grading the pain degree:
mild pain I
Moderate pain II
Severe pain of III
The standard of curative effect is as follows:
NR is ineffective: no significant change in pain compared to before treatment;
partial MR mitigation: pain relief is less than 60%;
AR is significantly alleviated: pain is reduced by 61-90%;
complete remission of CR: the pain is reduced by 91-100%.
Table 1: statistics of clinical analgesic experimental data
Clinical experiment 1 showed that the plaster of the present invention has effective rates of 70%, 80% and 90% for patients with abrasions, the plaster of example 4 is the most effective, and the use of the plaster of the present invention has a significant pain alleviation effect compared to the existing plaster of the fifth group and the physiological saline of the sixth group.
Plaster clinical experiment 2:
volunteers A, B and C were randomly selected for burns and scalds, patient a being a first degree burn, patient B being a shallow second degree burn, and patient C being a deep second degree burn, i.e., patient a's burn would damage a portion of the epidermis, patient B would damage the entire epidermis, and patient C would burn deep below the dermal papilla layer but still leave a portion of the dermis and skin appendages, healing being dependent on the skin appendage epithelium. When the plaster of the embodiment 4 of the invention is used by the patient A, the patient B and the patient C at the same time, the patient A can be directly cured after being used for 2 days, the patient B can be directly cured after being used for 6 days, and the patient C can be directly cured after being used for 14 days, namely, the plaster of the invention can play a good role in patients with different degrees of burns and scalds.
Plaster clinical trial 3:
60 patients with cracked hands and feet were randomly selected and divided into 5 groups, the first group was externally applied with the plaster prepared according to the formulation of example 1 of the present invention, the second group was externally applied with the plaster prepared according to the formulation of example 2 of the present invention, the third group was externally applied with the plaster prepared according to the formulation of example 3 of the present invention, the fourth group was externally applied with the plaster prepared according to the formulation of example 4 of the present invention, and the fifth group was externally applied with the existing "vanishing cream" plaster.
The standard of curative effect is as follows:
primary healing, moderate healing and complete healing.
Table 2: statistics of clinical laboratory data
In clinical experiment 3, the volunteers of the first group had an average time to complete healing of 7 days, the volunteers of the second group had an average time to complete healing of 6 days, the volunteers of the third group had an average time to complete healing of 7 days, the volunteers of the fourth group had an average time to complete healing of 5 days, and the volunteers of the fifth group had an average time to complete healing of 14 days. That is, the plaster of the present invention has a significant wound-healing effect on patients with cracked hands and feet, and the plaster corresponding to the fourth group is most effective.
It is worth mentioning that the plaster can be used for treating patients who have wounds which are not easy to heal due to diabetes, namely, the patients with diabetes are difficult to heal after the wounds appear, but the wounds can be quickly healed after the plaster is used for the patients, the healing speed of the patients is higher than that of the patients under normal conditions, and the overall effect is good.
In summary, the above embodiments are not intended to be limiting embodiments of the present invention, and modifications and equivalent variations made by those skilled in the art based on the spirit of the present invention are within the technical scope of the present invention.
Claims (6)
1. The plaster for treating the wound is characterized by comprising the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla, 1.3-1.6 parts of carbonized sanguisorba root, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline.
2. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla striata, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root, 0.45 part of Chinese angelica and 40 parts of vaseline.
3. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla striata, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root, 0.4 part of angelica and 45 parts of vaseline.
4. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 1.5 parts of calamine, 0.6 part of borneol, 1.1 parts of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla, 1.45 parts of carbonized sanguisorba root, 1.1 parts of divaricate saposhnikovia root, 0.6 part of Chinese angelica and 60 parts of vaseline.
5. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla striata, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root, 0.5 part of Chinese angelica and 50 parts of vaseline.
6. The preparation method of the plaster for treating the wound is characterized by comprising the following specific steps of:
s1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, carbonized sanguisorba root, divaricate saposhnikovia root and Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use;
s2, weighing vaseline in parts by weight, and heating;
and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
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CN102743484A (en) * | 2012-07-09 | 2012-10-24 | 中南大学湘雅三医院 | Plaster for treating skin disorder and preparation method thereof |
CN102908524A (en) * | 2012-10-25 | 2013-02-06 | 车延西 | External application Chinese medicine for treating burn and scald and use method thereof |
CN107007712A (en) * | 2017-04-11 | 2017-08-04 | 重庆大学 | Treat the externally applied drug of skin burn |
CN110693954A (en) * | 2019-11-04 | 2020-01-17 | 宫鹏 | Preparation method of ointment |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1403097A (en) * | 2002-10-18 | 2003-03-19 | 武汉马应龙药业集团股份有限公司 | Sore ulcer treating ointment and its prepn |
CN102743484A (en) * | 2012-07-09 | 2012-10-24 | 中南大学湘雅三医院 | Plaster for treating skin disorder and preparation method thereof |
CN102908524A (en) * | 2012-10-25 | 2013-02-06 | 车延西 | External application Chinese medicine for treating burn and scald and use method thereof |
CN107007712A (en) * | 2017-04-11 | 2017-08-04 | 重庆大学 | Treat the externally applied drug of skin burn |
CN110693954A (en) * | 2019-11-04 | 2020-01-17 | 宫鹏 | Preparation method of ointment |
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Application publication date: 20230120 |