CN115624593A - Plaster for treating wound and preparation method thereof - Google Patents

Plaster for treating wound and preparation method thereof Download PDF

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CN115624593A
CN115624593A CN202210490808.7A CN202210490808A CN115624593A CN 115624593 A CN115624593 A CN 115624593A CN 202210490808 A CN202210490808 A CN 202210490808A CN 115624593 A CN115624593 A CN 115624593A
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plaster
vaseline
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林健明
林浩翔
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Abstract

The invention provides a plaster for treating wounds and a preparation method thereof, wherein the plaster comprises the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla striata, 1.3-1.6 parts of garden burnet charcoal, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline, and the preparation method comprises the following specific steps of S1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, garden burnet charcoal, divaricate saposhnikovia root and Chinese angelica according to the parts by weight, mixing and grinding to form medicinal powder for later use; s2, weighing vaseline in parts by weight, and heating; and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound. The plaster can effectively relieve the pain of patients with wounds, can be used for patients with different degrees of wounds, helps the skin of the patients to heal quickly, and has good effect on the patients with different degrees of burns and scalds.

Description

Plaster for treating wound and preparation method thereof
Technical Field
The invention relates to the technical field of plaster, in particular to a plaster for treating wounds and a preparation method thereof.
Background
The skin is the tissue of the body surface wrapped outside the muscle, is the largest organ of the human body surface area, and mainly plays the roles of protecting the body, discharging sweat, feeling cold and heat, pressure and the like. The skin covers the whole body and protects various tissues and organs in the body from physical, mechanical, chemical and pathogenic microbial attacks. In daily life, skin injuries of different degrees are easily caused due to external and self factors, skin tissues can be separated or damaged after skin wounds, although the skin has certain self-healing capacity, the skin wounds such as burns and scalds which are not closed up due to old wounds and the skin diseases such as paronychia, tinea pedis, cracking of hands and feet and abrasion need to be treated by medicine intervention, the most commonly used medicine for the skin diseases with the symptoms is the external plaster, but the current external plaster on the market has complex prescription, complicated preparation process and insufficient skin repairing effect.
Disclosure of Invention
In order to solve the problems, the invention adopts the following technical scheme: a plaster for treating wounds is prepared from the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla, 1.3-1.6 parts of carbonized sanguisorba root, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla striata, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root, 0.45 part of angelica and 40 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla striata, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root, 0.4 part of Chinese angelica and 45 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 1.5 parts of calamine, 0.6 part of borneol, 1.1 parts of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla striata, 1.45 parts of carbonized sanguisorba root, 1.1 parts of divaricate saposhnikovia root, 0.6 part of angelica and 60 parts of vaseline.
Further, the plaster for treating the wound comprises the following raw materials in parts by weight: 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root, 0.5 part of Chinese angelica and 50 parts of vaseline.
A preparation method of a plaster for treating wound comprises the following specific steps:
s1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, carbonized sanguisorba root, divaricate saposhnikovia root and Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use;
s2, weighing vaseline in parts by weight, and heating;
and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
The beneficial effects of the invention are as follows: the plaster can effectively relieve the pain of patients with wounds, can be used for patients with different degrees of wounds, helps the skin of the patients to heal quickly, and has good effect on the patients with different degrees of burns and scalds.
Detailed Description
The technical solution of the present invention will be further described below, and the present invention is not limited to the following specific embodiments. It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
Specifically, the calamine can be used for astringing dampness, relieving itching and healing sore, and is used for treating unhealed ulcer, dribbling pus and skin itch, the borneol is used for treating sore and swollen pain and unhealed ulcer, the rosin is used for dispelling wind and drying dampness, expelling pus and drawing out pus and promoting granulation and relieving pain, the cinnabar is used for clearing heat and detoxicating and sore and ulcer pyogenic infections, the pseudo-ginseng is used for dissipating blood stasis and stopping bleeding, and relieving swelling and stopping pain, and the bletilla is used for astringing to stop bleeding and relieving swelling and promoting granulation, the sanguisorba officinalis is used for treating blood heat and bleeding, detoxifying and healing sore, burns, eczema and skin ulcer, the ledebouriella root is used for dispelling wind and eliminating dampness, relieving pain and preventing tetanus, and the angelica is used for enriching blood, activating blood and regulating menstruation and relieving pain.
Example 1:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root and 0.45 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 40 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the freshly heated Vaseline, is manually stirred, is directly kept stand and cooled after being uniformly stirred, and is finally cooled to room temperature to obtain the plaster.
Example 2:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root and 0.4 part of Chinese angelica according to the parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 45 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Example 3:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 1.5 parts of calamine, 0.6 part of borneol, 1.1 part of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla, 1.45 parts of garden burnet charcoal, 1.1 parts of divaricate saposhnikovia root and 0.6 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
Specifically, when all the raw materials are added together, the raw materials are not in sequence, and can be ground manually or by a grinder to finally form medicinal powder for later use.
S2, weighing 60 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Example 4:
the preparation method of the plaster for treating the wound comprises the following steps:
s1, weighing 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root and 0.5 part of Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use.
S2, weighing 50 parts of vaseline by weight and heating.
Specifically, vaseline is put into a heating vessel, and then heated to a boiling state.
And S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
Specifically, the ground medicinal powder is directly poured into the heated Vaseline, and is stirred manually, and after the mixture is stirred uniformly, the mixture is directly kept stand for cooling, and finally the mixture is cooled to room temperature to obtain the plaster.
Plaster clinical experiment 1:
60 patients with the same degree of bruise were randomly selected and divided into 6 groups, the first group was externally applied with the plaster of the formulation of example 1 of the present invention, the second group was externally applied with the plaster of the formulation of example 2 of the present invention, the third group was externally applied with the plaster of the formulation of example 3 of the present invention, the fourth group was externally applied with the plaster of the formulation of example 4 of the present invention, the fifth group was externally applied with the existing plaster, and the sixth group was externally applied with normal saline.
Grading the pain degree:
mild pain I
Moderate pain II
Severe pain of III
The standard of curative effect is as follows:
NR is ineffective: no significant change in pain compared to before treatment;
partial MR mitigation: pain relief is less than 60%;
AR is significantly alleviated: pain is reduced by 61-90%;
complete remission of CR: the pain is reduced by 91-100%.
Table 1: statistics of clinical analgesic experimental data
Figure BDA0003630878410000051
Clinical experiment 1 showed that the plaster of the present invention has effective rates of 70%, 80% and 90% for patients with abrasions, the plaster of example 4 is the most effective, and the use of the plaster of the present invention has a significant pain alleviation effect compared to the existing plaster of the fifth group and the physiological saline of the sixth group.
Plaster clinical experiment 2:
volunteers A, B and C were randomly selected for burns and scalds, patient a being a first degree burn, patient B being a shallow second degree burn, and patient C being a deep second degree burn, i.e., patient a's burn would damage a portion of the epidermis, patient B would damage the entire epidermis, and patient C would burn deep below the dermal papilla layer but still leave a portion of the dermis and skin appendages, healing being dependent on the skin appendage epithelium. When the plaster of the embodiment 4 of the invention is used by the patient A, the patient B and the patient C at the same time, the patient A can be directly cured after being used for 2 days, the patient B can be directly cured after being used for 6 days, and the patient C can be directly cured after being used for 14 days, namely, the plaster of the invention can play a good role in patients with different degrees of burns and scalds.
Plaster clinical trial 3:
60 patients with cracked hands and feet were randomly selected and divided into 5 groups, the first group was externally applied with the plaster prepared according to the formulation of example 1 of the present invention, the second group was externally applied with the plaster prepared according to the formulation of example 2 of the present invention, the third group was externally applied with the plaster prepared according to the formulation of example 3 of the present invention, the fourth group was externally applied with the plaster prepared according to the formulation of example 4 of the present invention, and the fifth group was externally applied with the existing "vanishing cream" plaster.
The standard of curative effect is as follows:
primary healing, moderate healing and complete healing.
Table 2: statistics of clinical laboratory data
Figure BDA0003630878410000061
In clinical experiment 3, the volunteers of the first group had an average time to complete healing of 7 days, the volunteers of the second group had an average time to complete healing of 6 days, the volunteers of the third group had an average time to complete healing of 7 days, the volunteers of the fourth group had an average time to complete healing of 5 days, and the volunteers of the fifth group had an average time to complete healing of 14 days. That is, the plaster of the present invention has a significant wound-healing effect on patients with cracked hands and feet, and the plaster corresponding to the fourth group is most effective.
It is worth mentioning that the plaster can be used for treating patients who have wounds which are not easy to heal due to diabetes, namely, the patients with diabetes are difficult to heal after the wounds appear, but the wounds can be quickly healed after the plaster is used for the patients, the healing speed of the patients is higher than that of the patients under normal conditions, and the overall effect is good.
In summary, the above embodiments are not intended to be limiting embodiments of the present invention, and modifications and equivalent variations made by those skilled in the art based on the spirit of the present invention are within the technical scope of the present invention.

Claims (6)

1. The plaster for treating the wound is characterized by comprising the following raw materials in parts by weight: 1-3 parts of calamine, 0.4-0.6 part of borneol, 0.8-1.2 parts of rosin, 0.08-0.15 part of cinnabar, 0.4-0.6 part of pseudo-ginseng, 1.4-1.6 parts of bletilla, 1.3-1.6 parts of carbonized sanguisorba root, 0.8-1.2 parts of divaricate saposhnikovia root, 0.4-0.6 part of Chinese angelica and 40-60 parts of vaseline.
2. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 3 parts of calamine, 0.4 part of borneol, 0.8 part of rosin, 0.15 part of cinnabar, 0.6 part of pseudo-ginseng, 1.45 parts of bletilla striata, 1.6 parts of carbonized sanguisorba root, 0.8 part of divaricate saposhnikovia root, 0.45 part of Chinese angelica and 40 parts of vaseline.
3. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 1 part of calamine, 0.5 part of borneol, 1.2 parts of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.4 parts of bletilla striata, 1.3 parts of carbonized sanguisorba root, 1.2 parts of divaricate saposhnikovia root, 0.4 part of angelica and 45 parts of vaseline.
4. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 1.5 parts of calamine, 0.6 part of borneol, 1.1 parts of rosin, 0.08 part of cinnabar, 0.4 part of pseudo-ginseng, 1.6 parts of bletilla, 1.45 parts of carbonized sanguisorba root, 1.1 parts of divaricate saposhnikovia root, 0.6 part of Chinese angelica and 60 parts of vaseline.
5. The plaster for treating the wound according to claim 1, which is prepared from the following raw materials in parts by weight: 2 parts of calamine, 0.5 part of borneol, 1 part of rosin, 0.1 part of cinnabar, 0.5 part of pseudo-ginseng, 1.5 parts of bletilla striata, 1.5 parts of carbonized sanguisorba root, 1 part of divaricate saposhnikovia root, 0.5 part of Chinese angelica and 50 parts of vaseline.
6. The preparation method of the plaster for treating the wound is characterized by comprising the following specific steps of:
s1, weighing calamine, borneol, rosin, cinnabar, pseudo-ginseng, bletilla striata, carbonized sanguisorba root, divaricate saposhnikovia root and Chinese angelica according to parts by weight, mixing and grinding to form medicinal powder for later use;
s2, weighing vaseline in parts by weight, and heating;
and S3, stirring and mixing the medicinal powder and the heated vaseline, and cooling to room temperature to obtain the plaster for treating the wound.
CN202210490808.7A 2022-05-07 2022-05-07 Plaster for treating wound and preparation method thereof Pending CN115624593A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1403097A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Sore ulcer treating ointment and its prepn
CN102743484A (en) * 2012-07-09 2012-10-24 中南大学湘雅三医院 Plaster for treating skin disorder and preparation method thereof
CN102908524A (en) * 2012-10-25 2013-02-06 车延西 External application Chinese medicine for treating burn and scald and use method thereof
CN107007712A (en) * 2017-04-11 2017-08-04 重庆大学 Treat the externally applied drug of skin burn
CN110693954A (en) * 2019-11-04 2020-01-17 宫鹏 Preparation method of ointment

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1403097A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Sore ulcer treating ointment and its prepn
CN102743484A (en) * 2012-07-09 2012-10-24 中南大学湘雅三医院 Plaster for treating skin disorder and preparation method thereof
CN102908524A (en) * 2012-10-25 2013-02-06 车延西 External application Chinese medicine for treating burn and scald and use method thereof
CN107007712A (en) * 2017-04-11 2017-08-04 重庆大学 Treat the externally applied drug of skin burn
CN110693954A (en) * 2019-11-04 2020-01-17 宫鹏 Preparation method of ointment

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Application publication date: 20230120