CN115569155A - Traditional Chinese medicine nasal paste for inducing resuscitation and preparation method thereof - Google Patents

Traditional Chinese medicine nasal paste for inducing resuscitation and preparation method thereof Download PDF

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Publication number
CN115569155A
CN115569155A CN202211156395.5A CN202211156395A CN115569155A CN 115569155 A CN115569155 A CN 115569155A CN 202211156395 A CN202211156395 A CN 202211156395A CN 115569155 A CN115569155 A CN 115569155A
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essential oil
chinese medicine
traditional chinese
paste
oil
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Inventor
刘孟楠
杨思进
罗钢
刘平
王绕琼
刘天助
刘佳利
任维
蒲清荣
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Affiliated Hospital of Traditional Chinese Medicine TCM of Southwest Medical University
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Affiliated Hospital of Traditional Chinese Medicine TCM of Southwest Medical University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/02—Recovery or refining of essential oils from raw materials
    • C11B9/025—Recovery by solvent extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention belongs to the technical field of nasal pastes, and discloses a traditional Chinese medicine nasal paste for inducing resuscitation and a preparation method thereof. The plant essential oil consists of 20-25 parts of musk essential oil, 20-25 parts of borneol essential oil, 20-25 parts of storax essential oil, 10-15 parts of menthol and 20-25 parts of ligusticum wallichii volatile oil in parts by mass. The outer layer of the plant essential oil is wrapped by a protective film. The back plaster consists of a plaster and medical non-woven fabrics. The lower layer of the medical non-woven fabric is fixed with plant essential oil the outer layer of which is wrapped with a protective film. The medical non-woven fabric and the plant essential oil of which the outer layer is wrapped by the protective film are fixed by an adhesive. The invention volatilizes a plurality of natural essential oil components of musk essential oil, borneol essential oil, storax essential oil, menthol and ligusticum wallichii volatile oil into nostrils, thereby not only effectively refreshing and inducing resuscitation, but also having high safety due to the natural essential oil components, being also used by children and having long persistence.

Description

Traditional Chinese medicine nasal paste for inducing resuscitation and preparation method thereof
Technical Field
The invention belongs to the technical field of nasal pastes, and particularly relates to a traditional Chinese medicine nasal paste for inducing resuscitation and a preparation method thereof.
Background
At present, unconsciousness refers to the symptoms of loss of consciousness and lack of response to environmental stimuli. Faint or faint is called syncope. It is usually caused by turbid phlegm, heat-toxin, trauma, adverse flow of qi and blood, yin-yang failure and other strong stimulation. Coma or syncope during the course of disease is usually a critical condition. The depth of unconsciousness is often related to the severity of the disease. Coma or syncope can occur in various diseases caused by exogenous heat and epidemic diseases, such as syncope, alopecia, epilepsy, apoplexy, heatstroke, poisoning, head injury, and electric shock.
Coma is caused by exogenous pathogenic factors and internal injury, and it is caused by invasion of heart and brain. The heart governs spirit and the brain is the house of spirit and clear orifices, which governs mental consciousness and thinking activity. Diseases caused by exogenous epidemic invasion, heat sinking into heart-nutrient or internal injury of phlegm-fire, disharmony of yin and yang, qi and blood, and upward disturbance of turbid pathogenic factors can cause blindness and blockage of the clear orifices.
At present, the market does not have very effective resuscitation inducing and refreshing products, and most products do not have good curative effect.
Most of nasal patches in the market aim at the problem of the nose, air circulation of the nose is improved, inflammation is reduced, and the like.
Through the above analysis, the problems and defects of the prior art are as follows: the prior art does not have a nose patch for inducing resuscitation by using plant essential oil; meanwhile, the existing resuscitation inducing and refreshing product has poor effect.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a traditional Chinese medicine nasal paste for inducing resuscitation and a preparation method thereof.
The invention is realized in such a way, the traditional Chinese medicine nasal paste for resuscitation consists of plant essential oil and a back paste;
the plant essential oil comprises, by mass, 20-25 parts of musk essential oil, 20-25 parts of borneol essential oil, 20-25 parts of storax essential oil, 10-15 parts of menthol and 20-25 parts of ligusticum wallichii volatile oil.
Further, the outer layer of the plant essential oil is wrapped by a protective film.
Further, the back patch consists of a glue patch and medical non-woven fabrics.
Further, the lower layer of the medical non-woven fabric is fixed with plant essential oil of which the outer layer is wrapped with a protective film.
Further, the medical non-woven fabric and the plant essential oil of which the outer layer is wrapped with the protective film are fixed by using an adhesive.
Further, the medical non-woven fabric upper layer is provided with the adhesive sticker.
Further, the glue paste is a transparent waterproof glue paste.
The invention also aims to provide a preparation method of the traditional Chinese medicine nasal paste for resuscitation, which is used for resuscitation, and the preparation method comprises the following steps:
step one, preparing ligusticum wallichii volatile oil; weighing Moschus essential oil, borneolum essential oil, storax essential oil, mentholum and rhizoma Ligustici Chuanxiong volatile oil at a certain ratio;
step two, uniformly mixing the musk essential oil, the borneol essential oil, the storax essential oil, the menthol and the ligusticum wallichii volatile oil to obtain plant essential oil;
and step three, after the adhesive plaster and the medical non-woven fabric are assembled, fixing the plant essential oil below the medical non-woven fabric to obtain the traditional Chinese medicine nasal plaster for inducing resuscitation.
Further, the preparation of the ligusticum wallichii volatile oil comprises the following steps:
firstly, obtaining a ligusticum chuanxiong hort raw material, washing the obtained ligusticum chuanxiong hort raw material for a period of time, and naturally drying the ligusticum chuanxiong hort raw material; crushing the air-dried ligusticum chuanxiong hort by using a crushing device, and sieving by using a 60-80-mesh sieve;
secondly, placing the smashed ligusticum chuanxiong hort powder in a carbon dioxide fluid extraction device, and extracting for 25 minutes at 35 ℃ and 30Mpa at the carbon dioxide flow rate of 35L/h;
and finally, centrifuging the obtained volatile oil by using a centrifugal device, reserving a lower oil phase, adding anhydrous sodium sulfate into the oil phase, and filtering under reduced pressure to remove the sodium sulfate to obtain the ligusticum wallichii volatile oil.
Further, before the third step, the method further comprises: wrapping the obtained plant essential oil with protective film.
In combination with the technical solutions and the technical problems to be solved, please analyze the advantages and positive effects of the technical solutions to be protected in the present invention from the following aspects:
first, aiming at the technical problems existing in the prior art and the difficulty in solving the problems, the technical problems to be solved by the technical scheme of the present invention are closely combined with results, data and the like in the research and development process, and some creative technical effects are brought after the problems are solved. The specific description is as follows:
the traditional Chinese medicine nasal paste for inducing resuscitation disclosed by the invention is added with the musk essential oil, the borneol essential oil, the storax essential oil, the menthol and the ligusticum wallichii volatile oil, the natural essential oil components are volatilized into nostrils, so that the traditional Chinese medicine nasal paste can effectively induce resuscitation, and meanwhile, the natural essential oil components are high in safety, can be used by children and are long in persistence.
Secondly, considering the technical scheme as a whole or from the perspective of products, the technical effect and advantages of the technical scheme to be protected by the invention are specifically described as follows:
the traditional Chinese medicine nasal paste for inducing resuscitation has the effect of inducing resuscitation. The invention provides a traditional Chinese medicine nasal paste with good effects of inducing resuscitation and inducing resuscitation.
Drawings
Fig. 1 is a flow chart of a preparation method of a traditional Chinese medicine nasal paste for inducing resuscitation according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and do not limit the invention.
1. Illustrative embodiments are explained. This section is an explanatory embodiment expanding on the claims so as to fully understand how the present invention is embodied by those skilled in the art.
The traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention consists of plant essential oil and a back paste.
The plant essential oil provided by the embodiment of the invention comprises, by mass, 20-25 parts of musk essential oil, 20-25 parts of borneol essential oil, 20-25 parts of storax essential oil, 10-15 parts of menthol and 20-25 parts of ligusticum wallichii volatile oil.
As shown in fig. 1, the preparation method of the traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention comprises the following steps:
s101, preparing the ligusticum wallichii volatile oil; weighing Moschus essential oil, borneolum essential oil, storax essential oil, mentholum and rhizoma Ligustici Chuanxiong volatile oil at a certain ratio;
s102, uniformly mixing the musk essential oil, the borneol essential oil, the storax essential oil, the menthol and the ligusticum wallichii volatile oil to obtain plant essential oil;
s103, after the adhesive plaster and the medical non-woven fabric are assembled, the obtained plant essential oil is wrapped by the protective film and then fixed below the medical non-woven fabric, and the traditional Chinese medicine nasal plaster for inducing resuscitation is obtained.
The preparation of the ligusticum wallichii volatile oil provided by the embodiment of the invention comprises the following steps:
firstly, obtaining a ligusticum chuanxiong hort raw material, washing the obtained ligusticum chuanxiong hort raw material for a period of time, and naturally drying the ligusticum chuanxiong hort raw material in the air; crushing the air-dried ligusticum chuanxiong hort by using a crushing device, and sieving by using a 60-80-mesh sieve;
secondly, placing the smashed ligusticum chuanxiong hort powder in a carbon dioxide fluid extraction device, and extracting for 25 minutes at 35 ℃ and 30Mpa at the carbon dioxide flow rate of 35L/h;
and finally, centrifuging the obtained volatile oil by using a centrifugal device, reserving a lower oil phase, adding anhydrous sodium sulfate into the oil phase, and filtering under reduced pressure to remove the sodium sulfate to obtain the ligusticum wallichii volatile oil.
The technical solution of the present invention is further described with reference to the following specific embodiments.
Example 1:
the preparation method of the traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention comprises the following steps:
preparing the volatile oil of the ligusticum wallichii; weighing 20 parts of musk essential oil, 20 parts of borneol essential oil, 20 parts of storax essential oil, 10 parts of menthol and 20 parts of ligusticum wallichii volatile oil according to a proportion;
uniformly mixing the weighed musk essential oil, borneol essential oil, storax essential oil, menthol and ligusticum wallichii volatile oil to obtain plant essential oil;
after the adhesive plaster and the medical non-woven fabric are assembled, the obtained plant essential oil is wrapped by the protective film and then fixed below the medical non-woven fabric, and the traditional Chinese medicine nasal plaster for inducing resuscitation is obtained.
Example 2:
the preparation method of the traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention comprises the following steps:
preparing the volatile oil of the ligusticum wallichii; weighing 22 parts of musk essential oil, 22 parts of borneol essential oil, 22 parts of storax essential oil, 13 parts of menthol and 22 parts of ligusticum wallichii volatile oil according to the proportion;
uniformly mixing the weighed musk essential oil, borneol essential oil, storax essential oil, menthol and ligusticum wallichii volatile oil to obtain plant essential oil;
and (3) assembling the adhesive plaster and the medical non-woven fabric, wrapping the obtained plant essential oil by using a protective film, and fixing the wrapped plant essential oil below the medical non-woven fabric to obtain the traditional Chinese medicine nasal plaster for inducing resuscitation.
Example 3:
the preparation method of the traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention comprises the following steps:
preparing the volatile oil of the hemlock parsley; weighing 25 parts of musk essential oil, 25 parts of borneol essential oil, 25 parts of storax essential oil, 15 parts of menthol and 25 parts of ligusticum wallichii volatile oil according to a proportion;
uniformly mixing the weighed musk essential oil, borneol essential oil, storax essential oil, menthol and ligusticum wallichii volatile oil to obtain plant essential oil;
after the adhesive plaster and the medical non-woven fabric are assembled, the obtained plant essential oil is wrapped by the protective film and then fixed below the medical non-woven fabric, and the traditional Chinese medicine nasal plaster for inducing resuscitation is obtained.
The technical effects of the present invention will be further explained below in conjunction with pharmacological analysis.
The Moschus is dried secretion of mature male sachet of forest musk deer moschiberezovski, horse musk deer M.sifanicus Przewalski or original musk deer M.moschiberus Linnaeus. Has the effects of inducing resuscitation, refreshing mind, promoting blood circulation, dredging channels, relieving swelling and pain. It can be used for treating block syndrome of unconsciousness, pyocutaneous disease, toxic swelling, scrofula, subcutaneous nodule, sore throat, amenorrhea due to blood stasis, abdominal mass, heart and abdomen pain, headache, traumatic injury, arthralgia due to wind-cold-dampness, dystocia, dead fetus, and retained afterbirth.
Borneolum, borneolum Syntheticum, pericarpium Citri Tangerinae, folium Artemisiae Argyi, borneolum Syntheticum, serissa japonica, SCUTELLARIA CIRCONIAE, MEISONG, bornyl alcohol, and MEISONG, is prepared from stem and leaf of blumea balsamifera of Compositae or branch and leaf of Cinnamomum camphora of Lauraceae by steam distillation and recrystallization. Can be used for treating block pattern of coma, conjunctival congestion with swelling and pain, sore throat, aphtha, sore and ulcer with swelling and pain, and unhealed ulcer.
Storax has the effects of inducing resuscitation and removing dirt, resolving stagnation and eliminating phlegm, and promoting qi circulation and relieving pain in traditional Chinese medicine.
Menthol, consisting of a saturated cyclic alcohol obtained from peppermint oil. Has effects of dispelling pathogenic wind, clearing heat away, and removing toxic substance. It is mainly used for treating headache, conjunctival congestion, affection of exogenous wind-heat, sore throat and teeth, and skin pruritus, and can be used for preparing algefacient, analgesic, and toothpaste.
Chuan Xiong (academic name: ligusticum chuanxiong Hort) is commonly used for activating blood and promoting qi, dispelling wind and relieving pain, chuan Xiong is pungent, warm, fragrant and dry, and can be scattered and ascended to the vertex; it enters the blood system and goes down to reach the blood sea. Promoting blood circulation and removing blood stasis, and is suitable for various diseases caused by blood stasis; can be used for treating headache due to wind, and rheumatalgia. Xiren is that Chuan Xiong is a qi-flowing medicine in blood, but it has the functions of dispersing acrid, relieving depression, dredging and relieving pain.
2. Application examples. In order to prove the creativity and the technical value of the technical scheme of the invention, the part is the application example of the technical scheme of the claims on specific products or related technologies.
The traditional Chinese medicine nasal paste for inducing resuscitation can be used as a daily nursing health product, and can effectively induce resuscitation.
3. Evidence of the relevant effects of the examples. The embodiment of the invention achieves some positive effects in the process of research and development or use, and has great advantages compared with the prior art, and the following contents are described by combining data, diagrams and the like in the test process.
40 mice with no obvious differences in body weight, physical signs and the like are taken, the male and female are half, after the mice are fed for 7 days in an adaptive mode, the mice are randomly divided into a blank group and a test group, and each group comprises 20 mice. During the trial, the mice had access to sufficient food and water. The light and shade cycle of the feeding environment is 12h, the room temperature is 21 +/-1 ℃, and the humidity is 55% +/-5%; the blank group is fed normally for 7d, and the test group sticks the traditional Chinese medicine nasal paste for inducing resuscitation provided by the embodiment of the invention to the lower part of the mouse nose, and the nasal paste is replaced every 12 hours for 7 days continuously.
The influence of the independent activity and the rolling fatigue of mice in the blank group and the test group is observed, and the effect of obviously improving the physical endurance of the nose paste for inducing resuscitation is found, so that the Chinese medicinal nose paste has the effect of inducing resuscitation.
The above description is only for the purpose of illustrating the embodiments of the present invention, and the scope of the present invention should not be limited thereto, and any modifications, equivalents and improvements made by those skilled in the art within the technical scope of the present invention as disclosed in the present invention should be covered by the scope of the present invention.

Claims (10)

1. A traditional Chinese medicine nasal paste for inducing resuscitation is characterized in that the traditional Chinese medicine nasal paste for inducing resuscitation consists of plant essential oil and a back paste;
the plant essential oil comprises, by mass, 20-25 parts of musk essential oil, 20-25 parts of borneol essential oil, 20-25 parts of storax essential oil, 10-15 parts of menthol and 20-25 parts of ligusticum wallichii volatile oil.
2. The traditional Chinese medicine nasal patch for inducing resuscitation as claimed in claim 1, wherein the outer layer of the vegetable essential oil is wrapped by a protective film.
3. The traditional Chinese medicine nasal paste for inducing resuscitation as claimed in claim 1, wherein the back paste is composed of a glue paste and medical non-woven fabric.
4. The traditional Chinese medicine nasal patch for inducing resuscitation as claimed in claim 3, wherein the lower layer of the medical non-woven fabric is fixed with plant essential oil of which the outer layer is wrapped with a protective film.
5. The nasal patch according to claim 4, wherein the medical non-woven fabric and the plant essential oil coated with the protective film are fixed by an adhesive.
6. The traditional Chinese medicine nasal paste for inducing resuscitation as claimed in claim 3, wherein the adhesive paste is disposed on the upper layer of the medical non-woven fabric.
7. The traditional Chinese medicine nasal paste for inducing resuscitation as claimed in claim 6, wherein the adhesive paste is a transparent waterproof adhesive paste.
8. The preparation method of the traditional Chinese medicine nasal paste for resuscitation as claimed in any one of claims 1 to 7, wherein the preparation method of the traditional Chinese medicine nasal paste for resuscitation comprises the following steps:
step one, preparing ligusticum wallichii volatile oil; weighing Moschus essential oil, borneolum essential oil, storax essential oil, mentholum and rhizoma Ligustici Chuanxiong volatile oil at a certain ratio;
step two, uniformly mixing the musk essential oil, the borneol essential oil, the storax essential oil, the menthol and the ligusticum wallichii volatile oil to obtain plant essential oil;
and step three, after the adhesive plaster and the medical non-woven fabric are assembled, fixing the plant essential oil below the medical non-woven fabric to obtain the traditional Chinese medicine nasal plaster for inducing resuscitation.
9. The method for preparing a Chinese medicinal nasal patch for inducing resuscitation as claimed in claim 8, wherein the preparation of the volatile oil of rhizoma Chuanxiong comprises:
firstly, obtaining a ligusticum chuanxiong hort raw material, washing the obtained ligusticum chuanxiong hort raw material for a period of time, and naturally drying the ligusticum chuanxiong hort raw material; crushing the air-dried ligusticum chuanxiong hort by using a crushing device, and sieving by using a 60-80-mesh sieve;
secondly, placing the smashed ligusticum chuanxiong hort powder in a carbon dioxide fluid extraction device, and extracting for 25 minutes at 35 ℃ and 30Mpa at the carbon dioxide flow rate of 35L/h;
and finally, centrifuging the obtained volatile oil by using a centrifugal device, reserving a lower oil phase, adding anhydrous sodium sulfate into the oil phase, and filtering under reduced pressure to remove the sodium sulfate to obtain the ligusticum wallichii volatile oil.
10. The method for preparing a traditional Chinese medicine nasal paste for inducing resuscitation as claimed in claim 8, further comprising, before step three: wrapping the obtained plant essential oil with protective film.
CN202211156395.5A 2022-09-22 2022-09-22 Traditional Chinese medicine nasal paste for inducing resuscitation and preparation method thereof Pending CN115569155A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101084928A (en) * 2007-06-18 2007-12-12 陈万盛 Volatile aromatic refrigerant refreshing agent and preparation method
CN102283891A (en) * 2011-05-06 2011-12-21 安徽丰乐香料有限责任公司 Medicament for accelerating post-anesthesia brain refreshing resuscitation and improving cognitive function of brain through olfactory pathway via nose
CN108938694A (en) * 2017-05-22 2018-12-07 吴伟 A kind of preparation method and applications of rhizome of chuanxiong ice spray

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101084928A (en) * 2007-06-18 2007-12-12 陈万盛 Volatile aromatic refrigerant refreshing agent and preparation method
CN102283891A (en) * 2011-05-06 2011-12-21 安徽丰乐香料有限责任公司 Medicament for accelerating post-anesthesia brain refreshing resuscitation and improving cognitive function of brain through olfactory pathway via nose
CN108938694A (en) * 2017-05-22 2018-12-07 吴伟 A kind of preparation method and applications of rhizome of chuanxiong ice spray

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