CN115552019A - 在髓样细胞和小胶质细胞中特异性表达治疗性蛋白的病毒载体 - Google Patents

在髓样细胞和小胶质细胞中特异性表达治疗性蛋白的病毒载体 Download PDF

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CN115552019A
CN115552019A CN202180034310.3A CN202180034310A CN115552019A CN 115552019 A CN115552019 A CN 115552019A CN 202180034310 A CN202180034310 A CN 202180034310A CN 115552019 A CN115552019 A CN 115552019A
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promoter
seq
functional fragment
sequence identity
viral vector
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乌尔里希·西尔弗
珍妮·莱辛巴赫
马蒂纳·努比
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Zurich Universitaet Institut fuer Medizinische Virologie
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Zurich Universitaet Institut fuer Medizinische Virologie
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CN202180034310.3A 2020-05-27 2021-04-07 在髓样细胞和小胶质细胞中特异性表达治疗性蛋白的病毒载体 Pending CN115552019A (zh)

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EP20176939 2020-05-27
EP20176939.5 2020-05-27
PCT/EP2021/059070 WO2021239308A1 (en) 2020-05-27 2021-04-07 Viral vectors expressing therapeutic proteins specifically in myeloid cells and microglia

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EP (1) EP4158035A1 (https=)
JP (2) JP7820823B2 (https=)
KR (1) KR20230018378A (https=)
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AU (1) AU2021280943A1 (https=)
BR (1) BR112022016715A2 (https=)
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US20240033332A1 (en) * 2020-12-17 2024-02-01 Kyoto University Agent for activating a neuron
WO2023109911A1 (en) * 2021-12-15 2023-06-22 National Institute Of Biological Sciences, Beijing Microglia having car and use thereof
WO2024036106A1 (en) * 2022-08-08 2024-02-15 The Board Of Trustees Of The Leland Stanford Junior University Embryo microglia complementation for in vivo microglia manipulation and production of a non-human animal model for validation of gene function and therapeutic screening

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WO2018169901A1 (en) * 2017-03-13 2018-09-20 Massachusetts Institute Of Technology Synthetic promoters
CN109868286A (zh) * 2017-12-05 2019-06-11 深圳先进技术研究院 一种慢病毒载体、慢病毒及其制备方法和应用

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KR20230018378A (ko) 2023-02-07
JP7820823B2 (ja) 2026-02-26
JP2023526773A (ja) 2023-06-23
EP4158035A1 (en) 2023-04-05
US20230227847A1 (en) 2023-07-20
BR112022016715A2 (pt) 2022-11-16
JP2026062601A (ja) 2026-04-09
CA3165462A1 (en) 2021-12-02
AU2021280943A1 (en) 2022-07-28
IL298093A (en) 2023-01-01
MX2022014766A (es) 2023-02-22
WO2021239308A1 (en) 2021-12-02

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