CN115536740A - 介导细胞内有效滞留cd3的空间构象表位及其应用 - Google Patents

介导细胞内有效滞留cd3的空间构象表位及其应用 Download PDF

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Publication number
CN115536740A
CN115536740A CN202110737014.1A CN202110737014A CN115536740A CN 115536740 A CN115536740 A CN 115536740A CN 202110737014 A CN202110737014 A CN 202110737014A CN 115536740 A CN115536740 A CN 115536740A
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antibody
antigen
sequence
seq
cell
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Chinese (zh)
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李俊
张鹏潮
张银航
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Fundamenta Therapeutics Inc
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Fundamenta Therapeutics Inc
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Priority to CN202110737014.1A priority Critical patent/CN115536740A/zh
Priority to PCT/CN2022/096017 priority patent/WO2023273762A1/fr
Publication of CN115536740A publication Critical patent/CN115536740A/zh
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CN202110737014.1A 2021-06-30 2021-06-30 介导细胞内有效滞留cd3的空间构象表位及其应用 Pending CN115536740A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202110737014.1A CN115536740A (zh) 2021-06-30 2021-06-30 介导细胞内有效滞留cd3的空间构象表位及其应用
PCT/CN2022/096017 WO2023273762A1 (fr) 2021-06-30 2022-05-30 Épitope conformationnel spatial induisant une rétention efficace de cd3 dans des cellules et son utilisation

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CN202110737014.1A CN115536740A (zh) 2021-06-30 2021-06-30 介导细胞内有效滞留cd3的空间构象表位及其应用

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Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA94211C2 (ru) * 2004-06-03 2011-04-26 Новиммюн С.А. Выделенное полностью человеческое моноклональное cd3 антитело
JP2010524851A (ja) * 2007-04-03 2010-07-22 マイクロメット アーゲー 種間特異的結合ドメイン
JP6130097B2 (ja) * 2008-10-01 2017-05-17 アムゲン リサーチ （ミュンヘン） ゲーエムベーハー ＰＳＣＡ×ＣＤ３、ＣＤ１９×ＣＤ３、Ｃ−ＭＥＴ×ＣＤ３、エンドシアリン×ＣＤ３、ＥｐＣＡＭ×ＣＤ３、ＩＧＦ−１Ｒ×ＣＤ３、またはＦＡＰアルファ×ＣＤ３の異種間特異的二重特異性単鎖抗体
EP4180458A1 (fr) * 2008-10-01 2023-05-17 Amgen Research (Munich) GmbH Anticorps bispécifique à chaîne unique psma x cd3 particulière d'une espèce à l'autre
JP6738285B2 (ja) * 2014-05-28 2020-08-12 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ヒト及びカニクイザルｃｄ３イプシロンに結合する抗体
WO2017008844A1 (fr) * 2015-07-14 2017-01-19 Biontech Ag Mimotopes peptidiques de la chaîne epsilon du co-récepteur des cellules t cd3 et leurs utilisations
WO2019033050A1 (fr) * 2017-08-11 2019-02-14 City Of Hope Molécule bispécifique de liaison à un antigène
JP7305624B2 (ja) * 2017-09-21 2023-07-10 ウーシー バイオロジクス アイルランド リミテッド 新規抗ＣＤ３ε抗体
WO2019133761A1 (fr) * 2017-12-27 2019-07-04 Teneobio, Inc. Anticorps spécifiques de l'hétérodimère cd3-delta/epsilon
US11639388B2 (en) * 2019-02-22 2023-05-02 Wuhan Yzy Biopharma Co., Ltd. CD3 antigen binding fragment and application thereof
CN111048154B (zh) * 2019-12-10 2023-06-06 上海药明生物技术有限公司 一种抗体表位作图的方法

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