CN115530889A - Tumor sampling equipment convenient for separating tumors - Google Patents
Tumor sampling equipment convenient for separating tumors Download PDFInfo
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- CN115530889A CN115530889A CN202211393828.9A CN202211393828A CN115530889A CN 115530889 A CN115530889 A CN 115530889A CN 202211393828 A CN202211393828 A CN 202211393828A CN 115530889 A CN115530889 A CN 115530889A
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 80
- 238000005070 sampling Methods 0.000 title claims abstract description 80
- 238000000926 separation method Methods 0.000 claims abstract description 6
- 230000005540 biological transmission Effects 0.000 claims description 99
- 238000002955 isolation Methods 0.000 claims 9
- 238000000034 method Methods 0.000 abstract description 13
- 230000008569 process Effects 0.000 abstract description 12
- 238000001514 detection method Methods 0.000 abstract description 9
- 230000035515 penetration Effects 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 description 5
- 239000007924 injection Substances 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 208000035269 cancer or benign tumor Diseases 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 231100000588 tumorigenic Toxicity 0.000 description 1
- 230000000381 tumorigenic effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
- A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention belongs to the technical field of medical sampling equipment, and particularly relates to tumor sampling equipment convenient for tumor separation, which comprises a fixed shell, wherein a puncture handle is fixedly connected to the side wall of the fixed shell, one end, close to the puncture handle, of the fixed shell is connected with a puncture depth detection unit, one end, far away from the puncture depth detection unit, of the fixed shell is set as a sampling end, the sampling end is connected with a puncture needle assembly, one end, far away from the sampling end, of the puncture needle assembly is set as a puncture end, one end, far away from the puncture end, of the puncture needle assembly penetrates through the sampling end and is positioned in the fixed shell, a first cavity is formed in the fixed shell, a driving unit is arranged in the first cavity, the puncture needle assembly drives sampling through the driving unit, an auxiliary sampling unit is communicated in the puncture needle assembly, and the auxiliary sampling unit is used for sampling by the auxiliary driving unit and is also convenient for releasing samples. This application can automatic intercepting tumour sample, release tumour sample, and the accurate depth of penetration of holding makes whole sample process more smooth, stable.
Description
Technical Field
The invention belongs to the technical field of medical sampling equipment, and particularly relates to tumor sampling equipment convenient for tumor separation.
Background
The tumor is a new organism formed by local tissue cell proliferation of an organism under the action of various tumorigenic factors, and the new organism is mostly in an occupied block-shaped protrusion, also called a neoplasm, and when the tumor is judged to be benign or malignant, a doctor needs to use a sampling device to sample the tumor for assay detection. However, the existing sampling equipment absorbs tumor tissues by negative pressure, the method has small wound and relieves the pain of patients, while the traditional needle tube sampling is not easy to succeed once by only depending on the negative pressure sampling, the adsorption process is not accurate enough, the puncture process is not stable enough, the intercepted samples are not easy to separate, and also need to be manually separated, and the whole sampling process is complicated; therefore, there is a need for a tumor sampling device that can automatically intercept and release tumor samples, and can accurately control the puncture depth, so that the whole sampling process can be more smooth and stable, and the tumor can be conveniently separated.
Disclosure of Invention
The invention aims to provide tumor sampling equipment for conveniently separating tumors, so as to solve the problems and achieve the purpose of effectively improving the stability and accuracy of sampling.
In order to achieve the purpose, the invention provides the following scheme: the utility model provides a tumor sampling equipment of convenient separation tumour, includes fixed casing, fixedly connected with puncture handle on the lateral wall of fixed casing, fixed casing is close to the one end of puncture handle is connected with puncture depth detecting element, fixed casing is kept away from the one end of puncture depth detecting element sets up to the sample site, the sample site is connected with the pjncture needle assembly, the pjncture needle assembly is kept away from the one end of sample site sets up to the puncture site, the pjncture needle assembly is kept away from the one end of puncture site is passed the sample site just is located in the fixed casing, first cavity has been seted up in the fixed casing, be provided with drive unit in the first cavity, the pjncture needle assembly passes through the drive unit drive sample, pjncture needle assembly in-connection has supplementary sample cell, supplementary sample cell is used for supplementaryly the drive unit sample and still be convenient for releasing the sample.
Preferably, the pjncture needle assembly includes outer needle subassembly and interior needle subassembly, outer needle subassembly cover is established the outside of interior needle subassembly, outer needle subassembly is kept away from the one end of puncture end can be dismantled and connect in on the sample collection end, interior needle subassembly passes the sample collection end just is located one end in the fixed casing with drive unit's output transmission is connected, supplementary sample collection unit passes outer needle subassembly with communicate in the interior needle subassembly.
Preferably, interior needle subassembly is including fixed connection's slide bar assembly, transmission nook closing member and interior sampling syringe needle in proper order, the slide bar assembly with drive unit's output transmission is connected, slide bar assembly pivoted is followed the sample direction simultaneously and is removed, the transmission nook closing member runs through the one end of sample end is located in the outer needle subassembly, interior sampling syringe needle is close to the puncture end sets up, supplementary sample unit with transmission nook closing member, the inboard intercommunication of interior sampling syringe needle.
Preferably, interior sample syringe needle is including cutting nook closing member and thin wall interior needle, the needle cover is established in the thin wall the outside of cutting nook closing member, the one end of cutting nook closing member with the transmission nook closing member is kept away from the one end of fixed casing is with axle center fixed connection, the other end fixedly connected with cutting edge of cutting nook closing member, the cutting edge is close to the puncture end, the thread groove has been seted up on the lateral wall of cutting nook closing member, the cutting nook closing member passes through the thread groove forms hollow sheet heliciform structure, the cutting edge is located the thread groove is kept away from the one end of transmission nook closing member, the needle is kept away from in the thin wall the one end of cutting edge is with axle center fixed connection on the cutting nook closing member, needle wall thickness is less than in the thin wall of transmission nook closing member.
Preferably, outer needle subassembly includes in proper order with outer needle of axle center fixed connection's screw thread end, first outer needle, second and third, the screw thread end is close to the one end of sample end with fixed casing threaded connection, the outer needle cover of third is established the outside of cutting needle core, the wall thickness of the outer needle of third is less than the wall thickness of the outer needle of second, supplementary sample unit passes through first outer needle with the inboard intercommunication of the outer needle of second.
Preferably, the drive unit includes fixed connection and is in motor in the first cavity, the rotation axis of motor is with axle center fixedly connected with threaded rod, the outside thread bush of threaded rod is equipped with transmission support assembly, transmission support assembly is in along sample direction sliding connection in the first cavity, transmission support assembly is kept away from the one end of motor with be provided with the clearance between the one end of threaded rod, the slide bar assembly is kept away from the one end of transmission nook closing member is passed transmission support assembly just still stretches into in the threaded rod, transmission support assembly with slide bar assembly, transmission nook closing member transmission are connected, the threaded rod with transmission support assembly passes through the flexible sample of slide bar assembly drive transmission nook closing member.
Preferably, the slide bar assembly include with transmission nook closing member with axle center fixed connection's axle core, the threaded rod is kept away from a pot head of motor is established the axle core passes the one end outside of transmission support assembly, the second spout has been seted up to the symmetry in the threaded rod, the second spout sets up along the sample direction, the outside symmetry fixedly connected with otic placode of axle core, it is two sets of the otic placode corresponds sliding connection respectively and is two sets of in the second spout, the transmission nook closing member the one end of axle core is rotated and is connected on the transmission support assembly, the transmission support assembly is kept away from the one end of motor with be close to in the fixed casing the butt has the spring between the one end of sample end, the spring housing is established the outside of transmission nook closing member.
Preferably, the transmission support assembly includes that the screw thread cover is established the threaded sleeve in the threaded rod outside, the fixed connecting rod of the symmetrical fixedly connected with in the limit portion of threaded sleeve, it is two sets of fixed connecting rod is kept away from with one end fixed connection of motor and still with be provided with between the threaded rod the clearance, the transmission nook closing in the fixed cover in the one end outside of axle core is equipped with fixed ring, and is two sets of fixed connecting rod is close to the same end outside screw thread cover of transmission nook closing in is equipped with the screw thread end cover, the transmission nook closing in the screw thread center, fixed ring is located the screw thread end cover is inboard and two sets of between the fixed connecting rod, fixed ring with between the inboard diapire of screw thread end cover fixed ring and two sets of between the fixed connecting rod respectively roll fit have a plurality of balls, the spring butt is in the screw thread end cover with be close to in the fixed shell between the one end of sample end.
Preferably, it is two sets of fixed connecting rod deviate from the side vertical fixedly connected with top shoe and lower slider respectively, the top shoe is close to the motor sets up, symmetry fixedly connected with fixed plate in the first cavity is two sets of first spout has been seted up respectively to the opposite side of fixed plate, all the top shoe with lower slider is along sampling direction sliding connection two sets of in the first spout.
Preferably, the puncture depth detection unit includes display screen and distance sensor, display screen fixed connection be in fixed casing is kept away from the one end outside of sample end, distance sensor fixed connection be in the first cavity, distance sensor's sense terminal and a set of go up the slider and correspond the setting.
The invention has the following technical effects: under the guidance of CT, the puncture needle assembly is penetrated through the skin and extended into the tumor by holding the puncture handle; the puncture depth detection unit is mainly used for judging puncture depth data through displacement of the puncture needle assembly and effectively combining with the CT to achieve the aim of accurate puncture; the driving unit is mainly used for driving the puncture needle assembly to puncture the tumor, and separating a part of tumor sample from the tumor; the auxiliary sampling unit is mainly used as an auxiliary driving unit, so that the sampling process is smoother and more stable, and the auxiliary driving unit can be used for separating a sample from the puncture needle assembly; on the whole, this application can automatic intercepting tumour sample, release tumour sample, can also accurately hold the depth of penetration, makes whole sampling process more smoothly with stable.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic external view of a sampling apparatus according to the present invention;
FIG. 2 is a schematic diagram of the internal structure of the sampling apparatus according to the present invention;
FIG. 3 is an enlarged view of part A of FIG. 2;
FIG. 4 is an enlarged view of a portion B of FIG. 2;
FIG. 5 is a schematic view of a cutting core according to the present invention;
FIG. 6 is a cross-sectional view of a threaded rod of the present invention;
wherein, 1, a puncture handle; 2. starting a switch; 3. a stationary housing; 4. a display screen; 5. a threaded end; 6. a negative pressure tube; 7. a first outer needle; 8. a second outer needle; 9. a third outer needle; 10. a first cavity; 11. a motor; 12. a distance sensor; 13. fixing the disc; 14. fixing a sleeve; 15. an upper slide block; 16. a threaded sleeve; 17. a lower slider; 18. fixing the connecting rod; 19. a threaded rod; 20. a shaft core; 21. a threaded end cap; 22. a via hole; 23. a transmission needle core; 24. a first chute; 25. cutting a needle core; 26. an ear plate; 27. a ball bearing; 28. fixing the circular ring; 29. a thin-walled inner needle; 30. a cutting edge; 31. a thread groove; 32. a second chute; 33. a needle opening; 34. a fixing plate; 35. a second cavity; 36. a liquid injection pipe; 37. a three-way joint; 38. a spring.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Referring to fig. 1-6, the invention provides a tumor sampling device convenient for tumor separation, which comprises a fixed shell 3, wherein a puncture handle 1 is fixedly connected to the side wall of the fixed shell 3, one end of the fixed shell 3, which is close to the puncture handle 1, is connected with a puncture depth detection unit, one end of the fixed shell 3, which is far away from the puncture depth detection unit, is set as a sampling end, the sampling end is connected with a puncture needle assembly, one end of the puncture needle assembly, which is far away from the sampling end, is set as a puncture end, one end of the puncture needle assembly, which is far away from the puncture end, penetrates through the sampling end and is positioned in the fixed shell 3, a first cavity 10 is formed in the fixed shell 3, a driving unit is arranged in the first cavity 10, the puncture needle assembly drives sampling through the driving unit, an auxiliary sampling unit is communicated in the puncture needle assembly, and the auxiliary sampling unit is used for sampling by the auxiliary driving unit and is also convenient for sample release.
Under the guidance of CT, the puncture needle assembly penetrates through the skin and extends into the tumor by holding the puncture handle 1; the puncture depth detection unit is mainly used for judging puncture depth data through displacement of the puncture needle assembly and effectively combining with the CT to achieve the aim of accurate puncture; the driving unit is mainly used for driving the puncture needle assembly to puncture the tumor, and cutting off a part of tumor samples and then separating from the tumor; the auxiliary sampling unit is mainly used as an auxiliary driving unit, so that the sampling process is smoother and more stable, and the auxiliary driving unit can be used for separating a sample from the puncture needle assembly; on the whole, this application can automatic intercepting tumour sample, release tumour sample, can also accurately hold the depth of penetration, makes whole sampling process more smoothly with stable.
According to the further optimized scheme, the puncture needle assembly comprises an outer needle assembly and an inner needle assembly, the outer needle assembly is sleeved on the outer side of the inner needle assembly, one end, far away from the puncture end, of the outer needle assembly is detachably connected to the sampling end, the inner needle assembly penetrates through the sampling end and is located at one end of the fixed shell 3 and is in transmission connection with the output end of the driving unit, and the auxiliary sampling unit penetrates through the outer needle assembly and is communicated with the inner needle assembly.
Firstly, incision treatment is carried out on the skin surface close to a tumor, the puncture handle 1 is held by hands through CT, so that the puncture needle assembly extends into the skin incision and reaches the tumor surface, then the inner needle assembly is driven by the driving unit to move, so that the inner needle assembly is punctured and sampled, and the auxiliary sampling unit is convenient for the inner needle assembly to release a tumor sample.
Further optimize the scheme, interior needle subassembly is including fixed connection's slide bar assembly, transmission nook closing member 23 and interior sampling syringe needle in proper order, and the slide bar assembly is connected with drive unit's output transmission, makes slide bar assembly pivoted while remove along the sample direction, and the one end that transmission nook closing member 23 runs through the sample end is located outer needle subassembly, and interior sampling syringe needle is close to the puncture end setting, and supplementary sampling unit communicates with transmission nook closing member 23, interior sampling syringe needle inboard.
The slide bar assembly is driven to rotate by starting the driving unit, and the transmission needle core 23 and the inner sampling needle head are synchronously driven to rotate, so that sampling is carried out by rotating and moving along the sampling direction.
According to a further optimized scheme, the inner sampling needle head comprises a cutting needle core 25 and a thin-wall inner needle 29, the thin-wall inner needle 29 is sleeved on the outer side of the cutting needle core 25, one end of the cutting needle core 25 is fixedly connected with one end, far away from the fixed shell 3, of the transmission needle core 23 through the same axis, a cutting edge 30 is fixedly connected to the other end of the cutting needle core 25, the cutting edge 30 is close to a puncture end, a thread groove 31 is formed in the side wall of the cutting needle core 25, the cutting needle core 25 forms a hollow thin-sheet thread structure through the thread groove 31, the cutting edge 30 is located at one end, far away from the transmission needle core 23, one end, far away from the cutting edge 30, of the thin-wall inner needle 29 is fixedly connected to the cutting needle core 25 through the same axis, and the wall thickness of the thin-wall inner needle 29 is smaller than that of the transmission needle core 23.
When the driving unit drives the slide bar assembly, the cutting needle core 25 and the thin-wall inner needle 29 are synchronously driven to rotate and move along the sampling direction, the cutting needle core 25 synchronously punctures in a rotating state, tumors can be cut, and cut tumor blocks enter the inner cavity of the cutting needle core 25, in the puncturing process, the thin-wall inner needle 29 synchronously moves along with the cutting needle core 25, the cut tumor blocks are ensured to be stored in the cutting needle core 25, when the inner sampling needle head is convenient to draw out, tissue fluid on the surface of the tumor blocks is prevented from polluting other tissues, and meanwhile, the integrity of a tumor sample is also ensured; the wall thickness of the thin walled inner needle 29 being less than the wall thickness of the driving hub 23 enables as much of the cutting hub 25 lumen to intercept the sample as possible.
Further optimize the scheme, outer needle subassembly includes in proper order with axle center fixed connection's screw thread end 5, first outer needle 7, the outer needle 8 of second and the outer needle 9 of third, and the one end and the fixed casing 3 threaded connection of the screw thread end 5 near the sample site, and the outer needle 9 cover of third is established in the outside of cutting needle core 25, and the wall thickness of the outer needle 9 of third is less than the wall thickness of the outer needle 8 of second, and supplementary sample unit is through the inboard intercommunication of the outer needle 8 of first outer needle 7 and second.
In the puncture, the third outer needle 9 and the second outer needle 8 enter the body from the skin incision in sequence, and the needle mouth 33 of the third outer needle 9 contacts the tumor surface firstly.
According to a further optimization scheme, the driving unit comprises a motor 11 fixedly connected in the first cavity 10, a rotating shaft of the motor 11 is coaxially and fixedly connected with a threaded rod 19, a transmission support assembly is sleeved on a thread on the outer side of the threaded rod 19 and is slidably connected in the first cavity 10 along the sampling direction, a gap is formed between one end, away from the motor 11, of the transmission support assembly and one end of the threaded rod 19, one end, away from the transmission needle core 23, of the slide rod assembly penetrates through the transmission support assembly and further extends into the threaded rod 19, the transmission support assembly is in transmission connection with the slide rod assembly and the transmission needle core 23, and the threaded rod 19 and the transmission support assembly drive the transmission needle core 23 to perform telescopic sampling through the slide rod assembly.
The motor 11 is started to rotate, the threaded rod 19 is driven to rotate, meanwhile, the transmission support assembly and the slide rod assembly are driven to slide along the sampling direction, when the transmission support assembly moves to one end, far away from the motor 11, of the threaded rod 19, the transmission support assembly is separated from the threaded section of the threaded rod 19, the transmission support assembly and the threaded rod 19 rotate relatively, the transmission support assembly does not move along the sampling direction along with the continuous rotation of the threaded rod 19 and the slide rod assembly, and at the moment, the slide rod assembly rotates to drive the cutting edge 30 to cut off the tumor block.
Further optimize the scheme, the slide bar assembly includes the axle core 20 with axle center fixed connection with transmission noose 23, the threaded rod 19 is kept away from a pot head of motor 11 and is established in the one end outside that axle core 20 passed transmission support assembly, the second spout 32 has been seted up to the symmetry in the threaded rod 19, second spout 32 sets up along the sample direction, the outside symmetry fixedly connected with otic placode 26 of axle core 20, two sets of otic placodes 26 correspond sliding connection respectively in two sets of second spouts 32, the one end that transmission noose 23 is close to axle core 20 rotates and connects on transmission support assembly, the butt has spring 38 between the one end that transmission support assembly kept away from motor 11 and the one end that is close to the sample end in the fixed casing 3, spring 38 cover is established in the outside of transmission noose 23.
The spring 38 is in a free state in an initial state, when the motor 11 rotates to drive the threaded rod 19 and the shaft core 20 to rotate, the shaft core 20 slides in the threaded rod 19 along the axis direction and the two groups of lug plates 26 slide in the second sliding grooves 32 through the transmission bracket assembly, and then the cutting needle core 25 is driven to rotate and move towards the sampling direction, so that a rotary cutting effect is formed; when the transmission bracket assembly is separated from the thread section of the threaded rod 19, the transmission bracket assembly and the threaded rod 19 rotate relatively, the spring 38 is compressed, and the cutting needle core 25 rotates and does not continue to puncture, the cutting edge 30 cuts off the intercepted tumor block; when the motor 11 is started reversely, the threaded rod 19 and the shaft core 20 are driven to rotate reversely, the transmission support assembly is connected with the threaded rod 19 again under the effect of the resilience force of the spring 38, the cutting edge 30 plays a role of bearing a tumor sample block at the moment, the tumor sample block is prevented from sliding away from the cutting needle core 25 in a rotating state, and the cut tumor block is driven to be separated from the tumor.
Further optimize the scheme, the transmission support assembly includes that the threaded sleeve 16 outside threaded rod 19 is established to the threaded sleeve cover, the limit symmetry fixedly connected with fixed connecting rod 18 of threaded sleeve 16, two sets of fixed connecting rod 18 keep away from motor 11 with one end fixed connection and still be provided with the clearance with threaded rod 19 between, the fixed cover that is equipped with fixed ring 28 in the one end outside that the transmission nook closing member 23 is close to axle core 20, two sets of fixed connecting rod 18 are close to the same one end outside threaded sleeve of transmission nook closing member 23 and are equipped with threaded end cover 21, transmission nook closing member 23 passes threaded end cover 21 center, fixed ring 28 is located between threaded end cover 21 inboard and two sets of fixed connecting rod 18, between the inboard diapire of fixed ring 28 and threaded end cover 21, between fixed ring 28 and two sets of fixed connecting rod 18 respectively roll the cooperation have a plurality of balls 27, spring 38 butt is in threaded end cover 21 and fixed casing 3 between the one end that is close to the sample end.
The balls 27 ensure that the driving needle core 23 is more smooth and stable in the rotating and puncturing process, and also help to intercept the integrity of the tumor sample.
Further optimize the scheme, the side that deviates from of two sets of fixed connecting rods 18 is vertical fixedly connected with top shoe 15 and lower slider 17 respectively, and top shoe 15 is close to motor 11 and sets up, and symmetrical fixedly connected with fixed plate 34 in first cavity 10, first spout 24 has been seted up respectively to the opposite side of two sets of fixed plates 34, and all top shoes 15 and lower slider 17 are along sample direction sliding connection in two sets of first spouts 24.
Further optimize the scheme, puncture depth detecting element includes display screen 4 and distance sensor 12, and 4 fixed connection of display screen are in the one end outside of fixed casing 3 keeping away from the sample end, and distance sensor 12 fixed connection is in first cavity 10, and distance sensor 12's sense terminal corresponds the setting with a set of top shoe 15.
The distance sensor 12 monitors the distance of the upper sliding block 15, so that the puncture depth of the transmission needle core 23 can be monitored in real time, the accuracy of puncture is guaranteed together with CT, and the stability and smoothness of the whole puncture process are guaranteed.
According to a further optimized scheme, a fixed disc 13 is fixedly connected in the first cavity 10, a fixed sleeve 14 penetrates through the center of the fixed disc 13, the fixed sleeve 14 is sleeved on the outer side of a rotating shaft of the motor 11, and a detection end of the distance sensor 12 penetrates through the fixed disc 13 and is arranged corresponding to the upper sliding blocks 15.
According to the further optimized scheme, a second cavity 35 is formed between the first outer needle 7 and the transmission needle core 23, a plurality of via holes 22 are formed in the side wall of the transmission needle core 23, a three-way joint 37 is fixedly communicated with the outer side wall of the first outer needle 7, one end, away from the first outer needle 7, of the three-way joint 37 is fixedly communicated with a negative pressure pipe 6 and a liquid injection pipe 36 respectively, the transmission needle core 23 is communicated with the negative pressure pipe 6 or the liquid injection pipe 36 through the via holes 22, one end, away from the three-way joint 37, of the negative pressure pipe 6 is communicated with a negative pressure device or an air pump, and one end, away from the three-way joint 37, of the liquid injection pipe 36 is communicated with a physiological saline injector.
When the cutting edge 30 cuts off a tumor block, the negative pressure equipment is started to adsorb a tumor sample on the cutting needle core 25, when the cutting needle core 25 needs to be pulled out of an incision, the tumor sample is effectively prevented from being separated from the cutting needle core 25, when the cutting needle core 25 is separated from a human body and extends into a preservation liquid, the negative pressure is stopped, the air pump is started, positive pressure is generated in the transmission needle core 23, and the tumor sample is pushed out; the cutting needle core 25 reaches the surface of the tumor, and before puncture, the normal saline injector can dilute tissue fluid on the surface of the tumor block or nearby the tumor block, so that the tissue fluid is prevented from influencing the intercepting amount of the tumor sample block, and meanwhile, the puncture is facilitated.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, are merely for convenience of description of the present invention, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
The above-described embodiments are only intended to illustrate the preferred embodiments of the present invention, and not to limit the scope of the present invention, and various modifications and improvements made to the technical solution of the present invention by those skilled in the art without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.
Claims (10)
1. A tumor sampling device for facilitating separation of a tumor, comprising: including stationary housing (3), fixedly connected with puncture handle (1) on the lateral wall of stationary housing (3), stationary housing (3) are close to the one end of puncture handle (1) is connected with puncture depth detecting element, stationary housing (3) are kept away from the one end of puncture depth detecting element sets up to the sample site, the sample site is connected with the pjncture needle assembly, the pjncture needle assembly is kept away from the one end of sample site sets up to the puncture site, the pjncture needle assembly is kept away from the one end of puncture site is passed the sample site just is located in stationary housing (3), first cavity (10) have been seted up in stationary housing (3), be provided with drive unit in first cavity (10), the pjncture needle assembly passes through the drive unit drive sample, the intercommunication has supplementary sample cell in the pjncture needle assembly, supplementary sample cell is used for supplementaryly the drive unit sample and the release sample of still being convenient for.
2. The tumor sampling apparatus for facilitating the isolation of a tumor according to claim 1, wherein: the puncture needle assembly comprises an outer needle assembly and an inner needle assembly, the outer needle assembly is sleeved on the outer side of the inner needle assembly, the outer needle assembly is far away from one end of the puncture end and can be detachably connected to the sampling end, the inner needle assembly penetrates through the sampling end and is located one end in the fixed shell (3) and connected with the output end of the driving unit in a transmission mode, and the auxiliary sampling unit penetrates through the outer needle assembly and is communicated with the inner needle assembly.
3. A tumor sampling device for facilitating the isolation of a tumor according to claim 2, wherein: interior needle subassembly is including fixed connection's slide bar assembly, transmission nook closing member (23) and interior sampling syringe needle in proper order, the slide bar assembly with drive unit's output transmission is connected, slide bar assembly pivoted is followed the sample direction simultaneously and is removed, transmission nook closing member (23) run through the one end of sample end is located in the outer needle subassembly, interior sampling syringe needle is close to the puncture end sets up, supplementary sample unit with transmission nook closing member (23), the inboard intercommunication of interior sampling syringe needle.
4. A tumor sampling apparatus for facilitating the isolation of tumors as claimed in claim 3, wherein: interior sample syringe needle includes needle (29) in cutting nook closing member (25) and the thin wall, needle (29) cover is established in the thin wall the outside of cutting nook closing member (25), the one end of cutting nook closing member (25) with transmission nook closing member (23) is kept away from the one end of fixed casing (3) is with axle center fixed connection, the other end fixedly connected with cutting edge (30) of cutting nook closing member (25), cutting edge (30) are close to the puncture end, thread groove (31) have been seted up on the lateral wall of cutting nook closing member (25), cutting nook closing member (25) pass through thread groove (31) form hollow thin slice screw thread structure, cutting edge (30) are located thread groove (31) are kept away from the one end of transmission nook closing member (23), needle (29) are kept away from in the thin wall the one end of cutting edge (30) is with axle center fixed connection in on cutting nook closing member (25), needle (29) is less than in the thin wall thickness of transmission nook closing member (23).
5. A tumor sampling device for facilitating the isolation of a tumor according to claim 4, wherein: outer needle subassembly is including outer needle (9) of the outer needle (8) of coaxial center fixed connection's screw thread end (5), first outer needle (7), second in proper order and third, screw thread end (5) are close to the one end of sample end with fixed casing (3) threaded connection, needle (9) cover is established outside the cutting needle core (25), the wall thickness of the outer needle (9) of third is less than the wall thickness of the outer needle (8) of second, supplementary sample unit passes through first outer needle (7) with the outer inboard intercommunication of needle (8) of second.
6. A tumor sampling apparatus for facilitating the isolation of tumors as claimed in claim 3, wherein: drive unit includes fixed connection and is in motor (11) in first cavity (10), the rotation axis of motor (11) is with axle center fixedly connected with threaded rod (19), the outside thread bush of threaded rod (19) is equipped with transmission support assembly, transmission support assembly is along sample direction sliding connection in first cavity (10), transmission support assembly is kept away from the one end of motor (11) with be provided with the clearance between the one end of threaded rod (19), the slide bar assembly is kept away from the one end of transmission nook closing member (23) is passed transmission support assembly just still stretches into in threaded rod (19), transmission support assembly with slide bar assembly, transmission nook closing member (23) transmission are connected, threaded rod (19) with transmission support assembly passes through the flexible sample of slide bar assembly drive transmission nook closing member (23).
7. The tumor sampling apparatus for facilitating the isolation of a tumor according to claim 6, wherein: the slide bar assembly include with transmission nook closing member (23) is with axle center fixed connection's axle core (20), threaded rod (19) are kept away from the pot head of motor (11) is established axle core (20) is passed the one end outside of transmission support assembly, second spout (32) have been seted up to the symmetry in threaded rod (19), second spout (32) are along the sample direction setting, the outside symmetry fixedly connected with otic placode (26) of axle core (20), two sets of otic placode (26) correspond sliding connection respectively and are two sets of in second spout (32), transmission nook closing member (23) are close to the one end of axle core (20) is rotated and is connected on the transmission support assembly, the transmission support assembly is kept away from the one end of motor (11) with be close to in fixed casing (3) the butt has spring (38) between the one end of sample end, spring (38) cover is established the outside of transmission nook closing member (23).
8. The tumor sampling apparatus for facilitating the isolation of a tumor according to claim 7, wherein: the transmission support assembly includes that the screw thread cover is established screw thread sleeve (16) in threaded rod (19) the outside, the limit symmetry fixedly connected with fixed connecting rod (18) of screw thread sleeve (16), two sets of fixed connecting rod (18) are kept away from motor (11) with one end fixed connection and still with be provided with between threaded rod (19) the clearance, transmission nook closing member (23) are close to the fixed cover in the one end outside of axle core (20) is equipped with fixed ring (28), two sets of fixed connecting rod (18) are close to the same end outside screw thread cover of transmission nook closing member (23) is equipped with screw end cover (21), transmission nook closing member (23) passes screw end cover (21) center, fixed ring (28) are located screw end cover (21) inboard and two sets of between fixed connecting rod (18), fixed ring (28) with between screw end cover (21) the inboard diapire fixed ring (28) and two sets of respectively roll the cooperation between fixed connecting rod (18) have a plurality of balls (27), spring (38) butt is in screw end cover (21) with fixed end cover (3) one end is close to the sample end between the end.
9. The tumor sampling apparatus for facilitating the isolation of a tumor according to claim 8, wherein: two sets of the side that deviates from of fixed connecting rod (18) is vertical fixedly connected with top shoe (15) and lower slider (17) respectively, top shoe (15) are close to motor (11) set up, symmetry fixedly connected with fixed plate (34) in first cavity (10), two sets of first spout (24), all have been seted up respectively to the opposite side of fixed plate (34 top shoe (15) with lower slider (17) are along sample direction sliding connection two sets of in first spout (24).
10. The tumor sampling apparatus for facilitating the isolation of a tumor according to claim 9, wherein: puncture depth detecting element includes display screen (4) and distance sensor (12), display screen (4) fixed connection be in fixed casing (3) are kept away from the one end outside of sample end, distance sensor (12) fixed connection be in first cavity (10), the sense terminal and a set of distance sensor (12) top shoe (15) correspond the setting.
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| CN115530889B (en) | 2023-10-31 |
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