CN115414112A - Ablation catheter - Google Patents
Ablation catheter Download PDFInfo
- Publication number
- CN115414112A CN115414112A CN202211034323.3A CN202211034323A CN115414112A CN 115414112 A CN115414112 A CN 115414112A CN 202211034323 A CN202211034323 A CN 202211034323A CN 115414112 A CN115414112 A CN 115414112A
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- Prior art keywords
- ablation
- section
- catheter
- electrode
- electrodes
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- 238000002679 ablation Methods 0.000 title claims abstract description 100
- 238000005452 bending Methods 0.000 claims abstract description 18
- 230000005684 electric field Effects 0.000 claims abstract description 18
- 239000008280 blood Substances 0.000 claims abstract description 11
- 210000004369 blood Anatomy 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- 229910000566 Platinum-iridium alloy Inorganic materials 0.000 claims description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 3
- 239000010931 gold Substances 0.000 claims description 3
- 229910052737 gold Inorganic materials 0.000 claims description 3
- 239000011810 insulating material Substances 0.000 claims description 3
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 claims description 3
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 abstract description 5
- 230000000638 stimulation Effects 0.000 abstract description 4
- 230000008602 contraction Effects 0.000 abstract description 2
- 238000007599 discharging Methods 0.000 abstract description 2
- 230000005855 radiation Effects 0.000 abstract description 2
- 230000008569 process Effects 0.000 description 5
- 230000002107 myocardial effect Effects 0.000 description 4
- 230000006907 apoptotic process Effects 0.000 description 3
- 238000005868 electrolysis reaction Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 206010003658 Atrial Fibrillation Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000005242 cardiac chamber Anatomy 0.000 description 2
- 238000004520 electroporation Methods 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 210000003492 pulmonary vein Anatomy 0.000 description 2
- 208000005189 Embolism Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003191 femoral vein Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1273—Generators therefor including multiple generators in one device
Abstract
The invention discloses an ablation catheter, comprising: a delivery catheter; the ablation section is arranged on one side of the delivery catheter and is pushed by the delivery catheter to enter the human body; the delivery catheter is connected with the ablation section through a bending section, and angle adjustment can be carried out through the bending section; the electrode is uniformly arranged on the ablation section, so that the electric field is more uniformly distributed, the outer side of the electrode is coated with an insulating layer, the electrode can be prevented from contacting with blood on the outer side, and the targeted cells at the ablation section are ablated through discharging. The device reduces the area of the electrode exposed outside of the ablation catheter by designing the electrode at the catheter, further reduces the possibility of generating bubbles by electrolyzing blood in an ablation state, and improves the operation safety; the electrodes are uniformly distributed on the annular ablation section, so that an electric field is more uniform, energy is more concentrated, range radiation is reduced, and the occurrence rate of contraction caused by muscle stimulation is reduced.
Description
Technical Field
The invention relates to the field of medical technical instruments, in particular to an ablation catheter.
Background
Pulsed Field Ablation PFA (Pulsed Field Ablation) is a novel Ablation mode for cell death based on an irreversible electroporation mechanism, and has the advantages of tissue specificity, non-thermal Ablation and the like, so that it is applied to atrial fibrillation Ablation.
The pulse energy was passed through a 90cm/110cm length pulse ablation catheter, through a femoral vein puncture, and into the heart chamber. A doctor operates the pulse ablation catheter, and after the pulse ablation catheter reaches a target position, pulse energy is emitted to ablate a target tissue, so that specific myocardial cell apoptosis is caused, and ectopic conduction is blocked; in the pulse ablation process, when an electric field is applied to blood, electrolysis and gas formation can be caused, the formation of microbubbles can be found through an ultrasonic technology in a heart chamber, potential risk of embolism can occur when the microbubbles enter a far-end blood vessel, and the publication No. CN114404018A provides a pulmonary vein PFA atrial fibrillation ablation catheter, when a memory ablation needle group extends out of the outer end of the outer catheter and is opened, the memory ablation needle can be well matched with the shape of the cavity of the pulmonary vein, so that the purpose that an ablation electrode is firmly attached to the myocardial wall is achieved; the arrangement of the width of the ablation electrode and the width of the memory ablation needle can isolate the ablation electrode from blood after the memory ablation needle is attached to the myocardial wall, cut off a low-resistance path of the blood and prevent bubbles from being generated by electrolysis. However, in the working process of the ablation electrode, the memory ablation needle needs to be tightly attached to the myocardial wall, muscle stimulation can be generated, and certain burden is caused on the heart.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides an ablation catheter.
In order to achieve the purpose, the invention adopts the following technical scheme: an ablation catheter comprising:
a delivery catheter;
the ablation section is arranged on one side of the delivery catheter and is pushed by the delivery catheter to enter the human body;
the delivery catheter is connected with the ablation section through a bending section, and angle adjustment can be carried out through the bending section;
the electrode is uniformly arranged on the ablation section, so that the electric field is more uniformly distributed, the outer side of the electrode is coated with an insulating layer, the electrode can be prevented from contacting with blood on the outer side, and the targeted cells at the ablation section are ablated through discharging.
As a further description of the above technical solution: the ablation section is annular, one side of the ablation section is connected with the bending section, and the extending angle of the ablation section is adjusted through the bending section.
As a further description of the above technical solution: the ablation section is provided with a plurality of electrodes.
As a further description of the above technical solution: the electrodes are arranged in an equally spaced circumferential array.
As a further description of the above technical solution: the electrodes are connected by a wire, which is disposed inside the delivery catheter.
As a further description of the above technical solution: the electrode is provided with an insulating layer by sticking at the position close to the annular outer side, and the electrode at the annular inner side is exposed outside.
As a further description of the above technical solution: the conveying conduit enters the interior of the human body through the working channel.
As a further description of the above technical solution: the material of the conveying conduit is an insulating material.
As a further description of the above technical solution: the electrode is made of platinum-iridium alloy or gold.
As a further description of the above technical solution: the material of the insulating layer is the same as the material of the conveying conduit.
The technical scheme has the following advantages or beneficial effects:
1. through the design of the electrode at the catheter, the area of the electrode exposed outside of the ablation catheter is reduced, the possibility of generating bubbles by electrolyzing blood in an ablation state is further reduced, and the operation safety is improved.
2. The electrodes are uniformly distributed on the annular ablation section, so that an electric field is more uniform, energy is more concentrated, range radiation is reduced, and the occurrence rate of contraction caused by muscle stimulation is reduced.
3. The electrode is wrapped in an insulating layer on the outer side of the catheter, and the electrode cannot block an electric field, so that ablation efficiency is not influenced.
Drawings
Fig. 1 is a perspective view of an ablation catheter in accordance with the present invention;
fig. 2 is a cross-sectional view of an ablation catheter in accordance with the present invention;
fig. 3 is a schematic diagram of an embodiment of the present invention.
Illustration of the drawings:
1. a delivery catheter; 2. an ablation section; 3. bending sections; 4. an electrode; 5. an insulating layer; 6. and a wire.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, the present invention provides an embodiment: an ablation catheter comprising: a delivery catheter 1; the ablation section 2 is arranged on one side of the delivery catheter 1 and is pushed by the delivery catheter 1 to enter the human body; the delivery catheter 1 is connected with the ablation section 2 through a bending section 3, and the angle can be adjusted through the bending section 3; and the electrode 4 is arranged on the ablation section 2 and discharges and ablates the targeted cells at the ablation section 2.
In this embodiment, one side of delivery catheter 1 is connected with section 3 of bending, through section 3 of bending with melt section 2 and be connected, drives section 3 of bending through the removal of delivery catheter 1, further drives and melts section 2 and remove, removes to target cell department until melting section 2, can carry out the pulse ablation to the target cell.
With the attached drawing, the ablation section 2 is annular, one side of the ablation section is connected with the bending section 3, and the extending angle of the ablation section 2 is adjusted through the bending section 3. The ablation section 2 is bent into a ring shape, so that the position of the targeted cells can be limited at the inner side of the annular ablation section 2, the position of the cells to be ablated is determined, and the electric field of pulse ablation is more concentrated; the ablation segment 2 may also be petal-shaped or spherical, etc.
A plurality of electrodes 4 are arranged on the ablation section 2, and the electrodes 4 are arranged in an equidistant circumferential array. The pulse current is released through the electrodes, a high-voltage electric field is formed through the annular ablation section 2, and the targeted cells are ablated, in the embodiment, the number of the electrodes 4 is 10, the electrodes are uniformly distributed on the ablation section 2, the high-voltage electric field is formed in the working process, and the targeted cells are subjected to irreversible electroporation to generate apoptosis through the high-voltage electric field generally within 400-2000v in the high-voltage electric field for PFA pulse ablation.
Referring to fig. 2, the electrodes 4 are connected through the wires 6, the wires 6 are arranged inside the conveying conduit 1, and the wires 6 connected with the electrodes 4 are hidden inside the conveying conduit 1, so that the wires 6 can move together with the electrodes 4, and meanwhile, the wires 6 can be protected from being damaged in the working process.
With reference to fig. 1, an insulating layer 5 is adhered to a portion of the electrode 4 close to the outer side of the ring, the electrode 4 at the inner side of the ring is exposed, in this embodiment, the insulating layer 5 is adhered to the outer side of the electrode 4, so that the contact area between the electrode 4 and blood during electrolysis in blood can be reduced, the electrode 4 is ring-shaped and is nested at the outer side of the ablation section 2, the insulating layer 5 is adhered to the surface of the electrode 4 at the outer side of the ring-shaped ablation section 2, the insulating layer 5 is not coated on the inner side electrode 4 of the ring-shaped ablation section 2, during an ablation operation, whether the generated electric field distribution is mainly concentrated in the ring or not is determined, and the target tissue within the ring is ablated through pulses.
In this embodiment, the delivery catheter 1 enters the inside of the human body through the working channel, and the ablation catheter enters the heart cavity by a guiding sheath or an interatrial puncture sheath, wherein the working channel is arranged to assist in delivering the ablation catheter into the heart cavity of the human body.
In this embodiment, the material of the conveying conduit 1 is an insulating material, the material of the insulating layer 5 is the same as that of the conveying conduit 1, and may be polyamide, which has a good insulating property, and the material of the electrode 4 is platinum-iridium alloy or gold, which has a good conductivity and is not easy to generate an electrolytic reaction with blood.
The working principle is as follows: the delivery catheter 1 pushes the ablation section 2 to be delivered to the targeted cells through the working channel, the ablation section 2 is provided with electrodes 4 which are uniformly distributed, the outer part of the electrode 4, which is located on the ablation section 2, is pasted with an insulating layer 5, the inner part, which is located on the ablation section 2, is exposed on the outer side, and in the ablation working process, the electrodes 4 at the ablation section 2 jointly form a high-voltage electric field to ablate the targeted cells which are located on the annular inner side of the ablation section 2.
Example 2
The invention provides another embodiment, the outer sides of the electrodes 4 at the ablation section 2 are all coated with the insulating layers 5, the electrodes 4 are all coated, the high-voltage electric field acts on targeted cells to cause apoptosis according to the principle of pulse ablation, the electrodes 4 are coated in the insulating layers 5 of the catheter, the electric field is not blocked, the ablation efficiency is not influenced, meanwhile, the electrodes 4 can be prevented from directly contacting with muscle tissues, bubbles are reduced, and meanwhile, the muscle stimulation is avoided.
Example 3
Referring to fig. 3, the present invention provides another embodiment, the ablation section 2 is in a wave shape, the electrodes 4 are disposed at the wave crests and the wave troughs, the electrodes 4 at the wave crests are connected in series, the electrodes 4 at the wave troughs are connected in series, the two electrodes are controlled by two wires 6, the wires 6 extend outwards and are connected with a controller, the two electrode circuits can be controlled respectively, the range of the electric field formed by the electrodes 4 can be adjusted, different electrode circuits can be switched according to the range of the targeted cells, and the range of the electric field ablation can be adjusted.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (10)
1. An ablation catheter, characterized by: the method comprises the following steps:
a delivery catheter (1);
the ablation section (2) is arranged on one side of the delivery catheter (1) and enters the human body under the pushing of the delivery catheter (1);
the delivery catheter (1) is connected with the ablation section (2) through a bending section (3), and angle adjustment can be carried out through the bending section (3);
the electrode (4) is uniformly arranged on the ablation section (2), so that the formed electric field is more uniformly distributed, an insulating layer (5) is coated on the outer side of the electrode (4), the electrode (4) can be prevented from contacting with blood on the outer side, and the targeted cells at the ablation section (2) are ablated through discharge.
2. An ablation catheter as in claim 1, wherein: the ablation section (2) is annular, one side of the ablation section is connected with the bending section (3), and the extending angle of the ablation section (2) is adjusted through the bending section (3).
3. An ablation catheter as in claim 1, wherein: the ablation section (2) is provided with a plurality of electrodes (4).
4. An ablation catheter as in claim 3, wherein: the electrodes (4) are arranged in an equidistant circumferential array.
5. An ablation catheter as in claim 3, wherein: the electrodes (4) are connected through a lead wire, and the lead wire is arranged inside the conveying conduit (1).
6. An ablation catheter as in claim 3, wherein: the electrode (4) is provided with an insulating layer (5) by sticking at the position close to the annular outer side, and the electrode (4) at the annular inner side is exposed outside.
7. An ablation catheter as in claim 1, wherein: the conveying catheter (1) enters the human body through the working channel.
8. An ablation catheter as in claim 1, wherein: the conveying conduit (1) is made of an insulating material.
9. An ablation catheter as in claim 3, wherein: the electrode (4) is made of platinum-iridium alloy or gold.
10. An ablation catheter as in claim 6, wherein: the material of the insulating layer (5) is the same as the material of the conveying conduit (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211034323.3A CN115414112A (en) | 2022-08-26 | 2022-08-26 | Ablation catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211034323.3A CN115414112A (en) | 2022-08-26 | 2022-08-26 | Ablation catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115414112A true CN115414112A (en) | 2022-12-02 |
Family
ID=84199573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211034323.3A Withdrawn CN115414112A (en) | 2022-08-26 | 2022-08-26 | Ablation catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115414112A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116919564A (en) * | 2023-09-18 | 2023-10-24 | 迈得诺医疗科技集团有限公司 | Pulse ablation catheter |
-
2022
- 2022-08-26 CN CN202211034323.3A patent/CN115414112A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116919564A (en) * | 2023-09-18 | 2023-10-24 | 迈得诺医疗科技集团有限公司 | Pulse ablation catheter |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20221202 |
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| WW01 | Invention patent application withdrawn after publication |