JPWO2019157285A5 - - Google Patents
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- JPWO2019157285A5 JPWO2019157285A5 JP2020564790A JP2020564790A JPWO2019157285A5 JP WO2019157285 A5 JPWO2019157285 A5 JP WO2019157285A5 JP 2020564790 A JP2020564790 A JP 2020564790A JP 2020564790 A JP2020564790 A JP 2020564790A JP WO2019157285 A5 JPWO2019157285 A5 JP WO2019157285A5
- Authority
- JP
- Japan
- Prior art keywords
- generator
- ablation
- integrated catheter
- cardiac
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000013153 catheter ablation Methods 0.000 claims 16
- 238000002679 ablation Methods 0.000 claims 15
- 230000000903 blocking effect Effects 0.000 claims 15
- 210000005003 heart tissue Anatomy 0.000 claims 14
- 239000012530 fluid Substances 0.000 claims 4
- 239000012636 effector Substances 0.000 claims 3
- 239000004020 conductor Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 229910021607 Silver chloride Inorganic materials 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- QAMFBRUWYYMMGJ-UHFFFAOYSA-N hexafluoroacetylacetone Chemical compound FC(F)(F)C(=O)CC(=O)C(F)(F)F QAMFBRUWYYMMGJ-UHFFFAOYSA-N 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000007674 radiofrequency ablation Methods 0.000 claims 1
- 230000002441 reversible effect Effects 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Claims (16)
非アブレーションブロッキング電流を生成するように構成された第１の発生器と、
アブレーションエネルギーモダリティを生成するように構成された第２の発生器と、
一体型カテーテルであって、前記一体型カテーテルは、前記第１の発生器および前記第２の発生器に対して結合されるように構成された近位端部と、遠位端部とを有し、
前記一体型カテーテルの前記近位端部から前記一体型カテーテルの前記遠位端部まで延在する導体であって、前記一体型カテーテルの内部に配設された導体、
前記一体型カテーテルの遠位ゾーンに配設され、前記第１の発生器に対して導電接続されるように構成された、少なくとも１つのブロッキング電極、および
前記一体型カテーテルの遠位ゾーンに配設され、前記第２の発生器に対して導電接続されるように構成された、少なくとも１つのアブレーションエンドエフェクタ
をさらに備える、一体型カテーテルと
を備え、
前記システムは、前記少なくとも１つのブロッキング電極を介して前記第１の発生器から心臓組織まで前記ブロッキング電流を送達することにより、前記心臓組織に可逆性ブロックをもたらすように構成され、
前記システムは、前記第２の発生器から前記少なくとも１つのアブレーションエンドエフェクタまで前記アブレーションエネルギーモダリティを送達することにより心臓組織をアブレーションするように構成される、電気生理学的心臓アブレーションシステム。 An electrophysiological (EP) cardiac ablation system,
A first generator configured to generate non-ablation blocking current,
With a second generator configured to generate ablation energy modality,
An integrated catheter, the integrated catheter has a proximal end configured to be coupled to the first generator and the second generator, and a distal end. death,
A conductor extending from the proximal end of the integrated catheter to the distal end of the integrated catheter and disposed within the integrated catheter.
At least one blocking electrode disposed in the distal zone of the integrated catheter and configured to be conductively connected to the first generator, and disposed in the distal zone of the integrated catheter. And with an integrated catheter further comprising at least one ablation end effector configured to be conductively connected to the second generator.
The system is configured to provide a reversible block to the heart tissue by delivering the blocking current from the first generator to the heart tissue via the at least one blocking electrode.
The system is an electrophysiological cardiac ablation system configured to ablate cardiac tissue by delivering the ablation energy modality from the second generator to the at least one ablation end effector.
非アブレーションブロッキング電流を生成するように構成された発生器と、
一体型カテーテルであって、前記一体型カテーテルは、前記発生器に対して結合されるように構成された近位端部と、遠位端部とを有し、前記一体型カテーテルは、
前記一体型カテーテルの近位ゾーンから前記一体型カテーテルの遠位ゾーンまで延在して、前記近位ゾーンおよび前記遠位ゾーン内に開口を画成する内部ルーメンであって、前記カテーテルの前記近位ゾーンから前記カテーテルの前記遠位ゾーンまで流れる導電性流体を助長するように構成された内部ルーメン、および
前記一体型カテーテルの前記遠位ゾーンの近傍に配設され、前記発生器に対して導電接続されるように構成された、少なくとも１つのアブレーション電極
を備える、一体型カテーテルと
を備え、
前記システムは、前記導電性流体を介して前記発生器から心臓組織まで前記非アブレーションブロッキング電流を送達することにより心臓組織を可逆的にブロックするように構成され、
前記システムは、前記発生器から前記少なくとも１つのアブレーション電極まで電流を送達することにより心臓組織をアブレーションするように構成される、電気生理学的心臓アブレーションシステム。 An electrophysiological (EP) cardiac ablation system,
With a generator configured to generate non-ablation blocking current,
An integrated catheter, the integrated catheter has a proximal end configured to be coupled to the generator and a distal end, and the integrated catheter is a single-piece catheter.
An internal lumen that extends from the proximal zone of the integrated catheter to the distal zone of the integrated catheter and defines an opening in the proximal zone and the distal zone, near the catheter. An internal lumen configured to facilitate the conductive fluid flowing from the position zone to the distal zone of the catheter, and placed near the distal zone of the integrated catheter and conductive to the generator. With an integrated catheter with at least one ablation electrode configured to be connected,
The system is configured to reversibly block the heart tissue by delivering the non-ablation blocking current from the generator to the heart tissue via the conductive fluid.
The system is an electrophysiological cardiac ablation system configured to ablate cardiac tissue by delivering an electric current from the generator to the at least one ablation electrode.
発生器に対して結合されるように構成された近位端部と、
遠位端部と、
前記一体型カテーテルの遠位端部の近傍に配設され、前記発生器に対して導電接続されるように構成された、少なくとも１つのブロッキング電極と、
前記一体型カテーテルの遠位端部の近傍に配設され、前記発生器に対して導電接続されるように構成された、少なくとも１つのアブレーション電極と
を備え、
前記一体型カテーテルは、前記少なくとも１つのブロッキング電極を介して前記発生器から心臓組織までブロッキング電流を送達することにより心臓組織をブロックするように構成され、
前記一体型カテーテルは、前記発生器から前記少なくとも１つのアブレーション電極まで電流を送達することにより心臓組織をアブレーションするように構成される、一体型カテーテル。 It ’s an integrated catheter,
Proximal ends configured to be coupled to the generator,
Distal end and
With at least one blocking electrode located near the distal end of the integrated catheter and configured to be conductively connected to the generator.
It comprises at least one ablation electrode disposed near the distal end of the integrated catheter and configured to be conductively connected to the generator.
The integrated catheter is configured to block the heart tissue by delivering a blocking current from the generator to the heart tissue via the at least one blocking electrode.
The integrated catheter is an integrated catheter configured to ablate heart tissue by delivering an electric current from the generator to the at least one ablation electrode.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862628810P | 2018-02-09 | 2018-02-09 | |
| US62/628,810 | 2018-02-09 | ||
| PCT/US2019/017215 WO2019157285A1 (en) | 2018-02-09 | 2019-02-08 | Systems and methods for cardiac conduction block |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021513432A JP2021513432A (en) | 2021-05-27 |
| JPWO2019157285A5 true JPWO2019157285A5 (en) | 2022-02-16 |
| JP7456944B2 JP7456944B2 (en) | 2024-03-27 |
Family
ID=67549693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564790A Active JP7456944B2 (en) | 2018-02-09 | 2019-02-08 | Systems and methods for cardiac conduction block |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210038101A1 (en) |
| EP (1) | EP3749194A4 (en) |
| JP (1) | JP7456944B2 (en) |
| CN (1) | CN111989036A (en) |
| AU (1) | AU2019216750A1 (en) |
| CA (1) | CA3090776A1 (en) |
| WO (1) | WO2019157285A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013188753A1 (en) | 2012-06-15 | 2013-12-19 | Case Western Reserve University | Therapy delivery devices and methods for non-damaging neural tissue conduction block |
| US10195434B2 (en) | 2012-06-15 | 2019-02-05 | Case Western Reserve University | Treatment of pain using electrical nerve conduction block |
| US20150238764A1 (en) | 2013-05-10 | 2015-08-27 | Case Western Reserve University | Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing |
| EP3359244B1 (en) | 2015-10-06 | 2020-12-23 | Case Western Reserve University | High-charge capacity electrodes to deliver direct current nerve conduction block |
| US10864373B2 (en) | 2015-12-15 | 2020-12-15 | Case Western Reserve University | Systems for treatment of a neurological disorder using electrical nerve conduction block |
| EP3606599A4 (en) | 2017-04-03 | 2021-01-13 | Presidio Medical, Inc. | Systems and methods for direct current nerve conduction block |
| CA3091769A1 (en) | 2018-02-20 | 2019-08-29 | Presidio Medical, Inc. | Methods and systems for nerve conduction block |
| US11752329B2 (en) | 2018-07-01 | 2023-09-12 | Presidio Medical, Inc. | Systems and methods for nerve conduction block |
| EP4061476A4 (en) | 2019-11-24 | 2023-12-13 | Presidio Medical, Inc. | Pulse generation and stimulation engine systems |
| CN115334989A (en) * | 2020-01-24 | 2022-11-11 | 阿弗拉公司 | System and associated method for cardiac ablation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5868743A (en) * | 1995-12-13 | 1999-02-09 | Children's Medical Center Corporation | Cardiac ablation system with low temperature target site identification |
| US6415178B1 (en) * | 1996-09-16 | 2002-07-02 | Impulse Dynamics N.V. | Fencing of cardiac muscles |
| US6428537B1 (en) * | 1998-05-22 | 2002-08-06 | Scimed Life Systems, Inc. | Electrophysiological treatment methods and apparatus employing high voltage pulse to render tissue temporarily unresponsive |
| US20080275439A1 (en) * | 2002-01-25 | 2008-11-06 | David Francischelli | Cardiac ablation and electrical interface system and instrument |
| US8073538B2 (en) * | 2003-11-13 | 2011-12-06 | Cardio Polymers, Inc. | Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart |
| US8657814B2 (en) * | 2005-08-22 | 2014-02-25 | Medtronic Ablation Frontiers Llc | User interface for tissue ablation system |
| JP5926806B2 (en) * | 2011-09-22 | 2016-05-25 | ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ | System and method for visualizing ablated tissue |
| US9381361B2 (en) * | 2011-10-04 | 2016-07-05 | The Board Of Trustees Of The Leland Stanford Junior University | Control of cardiac excitability using high frequency signals |
| CA3158197A1 (en) * | 2012-05-29 | 2013-12-05 | Autonomix Medical, Inc. | Endoscopic sympathectomy systems and methods |
| US20150045675A1 (en) * | 2012-06-01 | 2015-02-12 | Ary Chernomorsky | Percutaneous methods and devices for carotid body ablation |
| WO2014071111A1 (en) * | 2012-11-02 | 2014-05-08 | Brigham And Women's Hospital, Inc. | Method and apparatus for suppressing electromagnetic fields induced by a magnetic resonance imaging system in electronic cables and devices |
| US9770593B2 (en) * | 2012-11-05 | 2017-09-26 | Pythagoras Medical Ltd. | Patient selection using a transluminally-applied electric current |
| US10639098B2 (en) * | 2014-05-06 | 2020-05-05 | Cosman Instruments, Llc | Electrosurgical generator |
| EP3139853B1 (en) * | 2014-05-07 | 2018-12-19 | Pythagoras Medical Ltd. | Controlled tissue ablation apparatus |
-
2019
- 2019-02-08 WO PCT/US2019/017215 patent/WO2019157285A1/en unknown
- 2019-02-08 EP EP19750457.4A patent/EP3749194A4/en active Pending
- 2019-02-08 AU AU2019216750A patent/AU2019216750A1/en active Pending
- 2019-02-08 JP JP2020564790A patent/JP7456944B2/en active Active
- 2019-02-08 US US16/968,531 patent/US20210038101A1/en active Pending
- 2019-02-08 CN CN201980023079.0A patent/CN111989036A/en active Pending
- 2019-02-08 CA CA3090776A patent/CA3090776A1/en active Pending
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