CN113349920A - Pulse electric field ablation catheter for intravascular ablation - Google Patents

Pulse electric field ablation catheter for intravascular ablation Download PDF

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Publication number
CN113349920A
CN113349920A CN202110747999.6A CN202110747999A CN113349920A CN 113349920 A CN113349920 A CN 113349920A CN 202110747999 A CN202110747999 A CN 202110747999A CN 113349920 A CN113349920 A CN 113349920A
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electric field
electrode
ablation
guide channel
catheter
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Chinese (zh)
Inventor
王礼春
汤玮
刘梦辉
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Priority to CN202110747999.6A priority Critical patent/CN113349920A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06Measuring instruments not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00351Heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00595Cauterization
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1407Loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe

Abstract

The invention relates to a pulsed electric field ablation catheter for ablating in blood vessels, which comprises a catheter body, wherein an electrode assembly is arranged at the end part of the catheter body, and an electrode connector is arranged at the tail part of the catheter body; the electrode connector is connected with the electrode assembly through a lead arranged in the tube body and is used for controlling the electrode assembly to record an intracardiac electric signal and release a pulse electric field; the pipe body is also provided with a guide channel for the guide assembly to pass through. The pulse electric field ablation catheter for intravascular ablation can be guided into a target blood vessel of a heart through the cooperation of the guide channel and the guide assembly, carries out mapping in the target blood vessel and releases a high-energy pulse electric field capable of specifically damaging myocardial tissues, achieves the technical effect of treating the myocardial on the epicardial side near the blood vessel on the premise of not damaging the artery and vein blood vessels where the catheter is located, enlarges the approach of treating arrhythmia, and improves the safety and efficiency of the operation.

Description

Pulse electric field ablation catheter for intravascular ablation
Technical Field
The invention relates to the technical field of medical instruments, in particular to a pulsed electric field ablation catheter for intravascular ablation.
Background
The catheter ablation therapy is the main mode for clinically treating the tachyarrhythmia at present, and aims to destroy the origin or related structures of the arrhythmia to achieve the treatment effect. Currently, the clinical ablation damage modes mainly include heating generated by radio frequency current or freezing generated by liquid helium. Other examples include laser and microwave. All of these ablation modalities heat or cryonecrose the tissue of interest by "heat energy". Because the conduction of heat energy cannot distinguish tissues, when in treatment application, the peripheral structures of target myocardium to be damaged, irrelevant cardiac muscle, peripheral blood vessels, nerves, esophagus and other organs can be damaged indiscriminately and nonspecifically as long as the temperature reaches the damage degree, which is the main reason of clinical complications, such as phrenic nerve paralysis caused by damage to adjacent phrenic nerves during atrial fibrillation ablation, or catastrophic esophageal atrial fistula caused by damage to esophagus. In addition, clinically, there are some sources of arrhythmia or related critical tissues located at or near the epicardial myocardium, and the energy is difficult to reach this depth via conventional endocardial ablation, resulting in treatment failure. However, when these areas are adjacent to the coronary venous system and the ablation catheter is accessible via the coronary venous system, one can try to apply radiofrequency energy for ablation in the case of saline infusion, but there is a risk of damage to the coronary venous system itself or to the adjacent coronary arteries, which, particularly when the latter are damaged, can lead to acute myocardial infarction with serious complications.
Disclosure of Invention
Based on the above, the present invention aims to provide an intravascular ablation catheter using a pulse electric field to damage myocardium and a great difference between the threshold of the blood vessel, which can achieve the technical effect of treating the epicardial myocardium with lesion near the blood vessel without damaging the artery and vein blood vessels of the catheter by releasing a high-energy pulse electric field specific to the myocardium, thereby improving the safety and efficiency of arrhythmia surgery.
The invention is realized by the following technical scheme:
a pulsed electric field ablation catheter for ablating in blood vessels comprises a catheter body, wherein an electrode assembly is arranged at the end part of the catheter body, and an electrode connector is arranged at the tail part of the catheter body; the electrode connector is connected with the electrode assembly through a lead arranged in the tube body and is used for controlling the electrode assembly to release a pulse electric field; the pipe body is also provided with a guide channel for the guide assembly to pass through.
The pulsed electric field ablation catheter capable of being ablated in blood vessels can rapidly and accurately guide the catheter to reach target blood vessels.
Furthermore, one end of the guide channel is communicated with the end opening of the tube body, the other end of the guide channel is arranged on the side wall of the tube body, and the guide channel is used for passing through a guide wire.
Furthermore, one end of the guide channel is communicated with the end opening of the tube body, the other end of the guide channel is arranged at the tail of the tube body, and the guide channel is used for passing through a guide wire.
Furthermore, the other end opening of the guide channel is also provided with a one-way valve.
Furthermore, the other end of the guide channel is also connected with one end of a flushing pipe from the side, and the other end of the flushing pipe is provided with a three-way component which is used for flushing heparin saline to remove air in the guide channel.
Furthermore, one end of the guide channel is communicated with the end opening of the pipe body, and the other end of the guide channel is arranged at the tail part of the pipe body; the end of the tube body is further provided with a soft guide wire, the tail of the tube body is further provided with an operating handle for operating the soft guide wire, and the operating handle is connected with the soft guide wire through an adjusting wire arranged in the guide channel.
Further, the free end of the soft guide wire is provided with a fixed bending shaping section.
Furthermore, the material of the pipe body is gradually softened from the tail part to the end part of the pipe body;
and/or the presence of a gas in the gas,
the outer diameter of the pipe body is gradually reduced from the tail part to the end part.
Further, the electrode assembly includes first, second, third and fourth electrodes disposed at the end of the tube at equal intervals.
Further, the first electrode, the second electrode, the third electrode, and the fourth electrode are ring-shaped electrodes.
The invention has the beneficial effects that:
1. the pulse electric field ablation catheter for intravascular ablation is applied to blood vessels, and the blood vessels are in circuitous running, have multiple branches and are different in pipe diameter size, and is guided to enter target blood vessels through the guide channel and the guide assembly, so that the catheter is more convenient to use due to the arrangement of the guide channel and the guide assembly, and the damage to the blood vessels can be reduced;
2. the pulse electric field ablation catheter for intravascular ablation is provided with a softer front section and a gradually hardened rear section, so that the catheter is convenient to push and can better enter blood vessels;
3. when the first electrode, the second electrode, the third electrode and the fourth electrode of the intravascular ablation pulsed electric field ablation catheter are ablated, mapping can be carried out simultaneously, pulsed electric fields can be selectively distributed between the two different electrodes, the artery and the vein are not damaged, and the safety and the efficiency of the operation are improved.
For a better understanding and practice, the invention is described in detail below with reference to the accompanying drawings.
Drawings
FIG. 1 is a schematic structural view of an embodiment of an intravascular ablation pulsed electric field ablation catheter of the present invention;
FIG. 2 is a schematic structural view of an embodiment of an intravascular ablation pulsed electric field ablation catheter of the present invention;
fig. 3 is a schematic structural view of an embodiment of an intravascular ablation pulsed electric field ablation catheter of the present invention.
Reference numerals: 10. a pulsed electric field ablation catheter for intravascular ablation; 11. a pipe body; 12. an electrode assembly; 121. a first electrode; 122. a second electrode; 123. a third electrode; 124. a fourth electrode; 13. an electrode connector; 14. a guide channel; 15. a first opening; 16. a second opening; 20. a pulsed electric field ablation catheter for intravascular ablation; 21. a pipe body; 22. an electrode assembly; 221. a first electrode; 222. a second electrode; 223. a third electrode; 224. a fourth electrode; 23. an electrode connector; 24. a guide channel; 241. a tee assembly; 242. a flush pipe; 25. a first opening; 26. a second opening; 30. a pulsed electric field ablation catheter for intravascular ablation; 31. a pipe body; 32. an electrode assembly; 321. a first electrode; 322. a second electrode; 323. a third electrode; 324. a fourth electrode; 33. an electrode connector; 34. a soft guide wire; 35. adjusting the silk; 36. and a handle is operated.
Detailed Description
The following are specific embodiments of the present invention and are further described with reference to the drawings, but the present invention is not limited to these embodiments.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
The pulse electric field ablation is to generate a plurality of small holes on a cell membrane through a high-energy electric field, so that the cell membrane is killed due to abnormal exchange of substances inside and outside the cell, and therefore, fibrous tissues and the like with non-cellular structures are not damaged, and the structure of the tissue can be well maintained when the cell is dead.
In addition, different tissue cells have different damage threshold values to the pulse electric field, and experiments show that the threshold value of myocardial damage is lower, and the blood vessel and the esophagus are not influenced when the threshold energy of the myocardial damage is applied for ablation, so that the myocardial tissue specificity is very strong, and the complications in the operation treatment can be reduced.
Arrhythmia can occur in any part of the heart, and when it occurs in the epicardial myocardium, the treatment fails because the myocardium has a certain thickness and the epicardial myocardium where the lesion is located can not be affected by the conventional intracardial catheter ablation.
Aiming at the technical defect that normal tissues are damaged due to arrhythmia treatment in a heat energy damage mode such as heating generated by radio frequency current in the related technology, the invention provides the intravascular ablation pulsed electric field catheter, which can accurately apply a high-energy pulsed energy source to target tissues to generate a pulsed electric field and improve the treatment success probability.
The main inventive concept of the pulsed electric field ablation catheter for intravascular ablation of the invention is to provide a catheter body of the ablation catheter, wherein an electrode assembly for mapping and releasing a high-energy pulsed electric field in a blood vessel is arranged at the end part of the catheter body, and an electrode connector is arranged at the tail part of the catheter body, wherein the end part of the catheter body is the end which enters the human body, and the tail part of the catheter body is the end which does not enter the human body and is kept outside the human body so as to be operated.
The electrode connector is connected with the electrode assembly through a lead arranged in the tube body, is used for connecting the pulse electric field ablation instrument and the multi-lead physiological recorder, records an intracardiac electric signal and controls the electrode assembly to map and release a high-energy pulse electric field.
In addition, a guide channel for a guide assembly to pass through is arranged in the tube body, and the guide assembly is used for guiding the end part of the tube body to the position of the target blood vessel.
Wherein the guide member may be a guide wire which is passed through the guide channel.
In addition, the guiding assembly can also consist of a control handle, an adjusting wire and a soft guide wire, the control handle and the soft guide wire are arranged at two ends of the guiding channel, and the adjusting wire penetrates through the guiding channel.
The pulse electric field ablation catheter for intravascular ablation can be guided or actively enter target blood vessels of the heart distributed on the epicardium through the matching of the guide channel and the guide wire or through the control of the soft guide wire at the end part of the catheter body to carry out mapping, and can pass through a high-energy pulse electric field which specifically damages the myocardium at a target point, thereby realizing the technical effect of treating the lesion on the epicardium myocardium near the blood vessels on the premise of not damaging the artery and vein blood vessels, and improving the safety and the efficiency of arrhythmia operation.
The following is a list of some specific embodiments implemented according to the above inventive concept, but the present invention is not limited to these specific embodiments, and any embodiment obtained according to the above inventive concept falls within the scope of the present invention.
The first embodiment is as follows:
as shown in fig. 1, a pulsed electric field ablation catheter 10 for intravascular ablation in the first embodiment includes a tube 11, an electrode assembly 12 and an electrode connector 13, wherein the electrode assembly 12 is disposed at an end of the tube 11, and the electrode connector 13 is disposed at a tail of the tube 11. The end of the tube body 11 of the pulsed electric field ablation catheter 10 for intravascular ablation is used for deep inside of a blood vessel for mapping and ablation treatment, and preferably, the end of the tube body 11 is tapered.
The electrode connector 13 is connected with the electrode assembly 12 through a conducting wire arranged in the tube body 11, the other end of the electrode connector 13 is used for connecting a pulse electric field ablation instrument and a multi-lead physiological recorder, and the electrode connector 13 is used for recording an intracardiac electric signal through the electrode assembly 12 and controlling the electrode assembly 12 to release a high-energy pulse electric field.
In the first embodiment, the pulsed electric field ablation catheter 10 for intravascular ablation is introduced into a target blood vessel through a guide wire as a guide component, and a guide channel 14 for accommodating the guide wire is arranged in the tube 11.
As shown in fig. 1, the end of the tube 11 is provided with a second opening 16, a first opening 15 is further provided on the side wall of the middle portion of the tube 11, one end of the guide channel 14 is communicated with the second opening 16, and the other end of the guide channel 14 is communicated with the first opening 15, wherein the first opening 15 is provided on the side wall of the tube 11, so that blood does not flow out of the body through the guide channel.
To enable more accurate mapping and release of high voltage, high energy pulsed electric fields, the electrode assembly 12 includes a first electrode 121, a second electrode 122, a third electrode 123, and a fourth electrode 124. The first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124 are sequentially disposed at the end of the tube 11 at equal intervals, and insulators are disposed between the first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124.
Preferably, as shown in fig. 1, the first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124 are ring-shaped electrodes.
Preferably, the inter-electrode distance between the first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124 is 1.5-3.0 mm.
Preferably, the cross-sectional area of the first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124 is 1.0 to 5.0 square millimeters.
In order to facilitate the tube 11 to be safely advanced to the blood vessel without damaging the blood vessel wall, it is preferable that the material of the tube 11 is gradually softened from the tail portion to the end portion of the tube 11.
Meanwhile, in order to enable the end of the tube body 11 to enter the tiny blood vessels for mapping and ablation, the outer diameter of the tube body 11 is gradually reduced from the tail part to the end part.
The pulse electric field ablation catheter for intravascular ablation in the first embodiment comprises the following working processes:
the guiding guide wire is placed at the far end of a target blood vessel to be mapped and ablated under the mediation of a conventional controllable long sheath or coronary guiding sheath, the tail part of the guiding guide wire is led into the guiding channel 14 from the second opening 16 and is led out of the guiding channel 14 from the first opening 15, the end part of the tube body 11 is led into the target blood vessel along the direction of the guiding guide wire under the guidance of the guiding guide wire, and then the first electrode 121, the second electrode 122, the third electrode 123 and the fourth electrode 124 are controlled by a pulse electric field ablation instrument and a multi-lead physiological recorder to map the target tissue and release a high-energy pulse electric field at a proper target point to destroy the lesion tissue.
In the process, because the threshold value of myocardial damage is lower and the threshold value of damage of blood vessels and esophageal cells is higher, the energy generated by the high-energy pulse electric field only damages target myocardial tissues during ablation, does not affect the blood vessels and the esophagus, reduces complications during surgical treatment, and improves the safety and efficiency of arrhythmia surgery; in addition, the first opening 15 and the second opening 16 are both located within the blood vessel or heart chamber so that blood does not flow out of the body during treatment.
Example two:
in the second embodiment, the pulsed electric field ablation catheter 20 for intravascular ablation has substantially the same structure as that of the first embodiment, and the main difference is that the guiding channel is arranged differently.
As shown in fig. 2, the pulsed electric field ablation catheter 20 for intravascular ablation is introduced into a target blood vessel through a guide wire as a guide component, and based on this, as shown in fig. 2, in the second embodiment, the end of the tube 21 is provided with a second opening 26, a first opening 25 is further provided on the tail of the tube 21, one end of the guide channel 24 is communicated with the second opening 26, and the other end of the guide channel 24 is communicated with the first opening 25.
A one-way valve (not shown) is arranged in the guide channel 24, preferably in the first opening 25, for preventing blood from flowing out of the body along with the guide channel.
Preferably, the other end of the guide channel 24 is also laterally connected to one end of the flush pipe 242, and a three-way valve 241 is disposed in the other end of the flush pipe 242, and the three-way valve 241 is used for flushing the heparin saline to remove air in the guide channel 24, and in particular, may be a three-way valve.
In the second embodiment, the one-way valve and the three-way valve 241 are both used to prevent blood from flowing out of the body along with the guide channel 24.
The operation process of the pulsed electric field ablation catheter for intravascular ablation in the second embodiment is as follows:
the end of the guide wire is passed through the guide channel 24 from the first opening 25 and out of the guide channel 24 from the second opening 26, the catheter tube with the guide wire assembled is then advanced, guided by a conventional steerable long sheath or coronary guide sheath, into the vicinity of the target vessel, the guide wire is maneuvered into the distal end of the target vessel to be mapped and ablated, and the end of the tube 21 is then guided in the direction of the guide wire to the location of the target vessel.
Then, the first electrode 221, the second electrode 222, the third electrode 223 and the fourth electrode 224 are controlled by the pulsed electric field ablation instrument and the multi-lead physiological recorder to map the target tissue and release a high-energy pulsed electric field, so that the target myocardial tissue is damaged; in the above process, the one-way valve and the three-way component 241 are arranged, so that the blood can not flow out of the body along the first opening of the guide channel during the treatment process.
Example three:
in the third embodiment, the pulsed electric field ablation catheter 30 for intravascular ablation is basically the same as the first and second embodiments, and the main difference is the arrangement of the guide channel.
In the third embodiment, the pulsed electric field ablation catheter 30 for intravascular ablation is introduced into a target blood vessel through the soft guide wire 34, the adjusting wire 35 and the control handle 36 as a guiding component, based on which, as shown in fig. 3, the soft guide wire 34 is arranged at the end of the tube body 31 and extends forwards from the end of the tube body 31, preferably, the soft guide wire 34 is a bent soft guide wire, and the soft guide wire 34 is provided with a fixed bent shaping section at the free end of the tip to facilitate the safe introduction of the soft guide wire 34 into a branch blood vessel.
The adjusting wire 35 penetrates through the guiding channels at the end and the tail of the tube 31 and is connected with an operating handle 36 arranged at the tail of the tube 31. The control handle 36 pulls the soft guide wire 34 through the adjusting wire 35, so that the soft guide wire 34 has a certain range of direction adjustment, and is convenient to enter a target blood vessel.
The operation process of the pulsed electric field ablation catheter for intravascular ablation in the third embodiment is as follows:
the operating handle 36 controls the soft guide wire 34 at the end of the tube body 31 through the adjusting wire 35 arranged in the guiding channel, so that the soft guide wire 34 can perform direction adjustment within a certain range in the blood vessel, thereby guiding the tube body 31 into a target blood vessel, and then the first electrode 321, the second electrode 322, the third electrode 323 and the fourth electrode 324 are controlled by the pulsed electric field ablation instrument and the multi-guide physiological recorder to map the target tissue and release the high-energy pulsed electric field, so as to destroy the target myocardial tissue.
Compared with the prior art, the pulse electric field ablation catheter for intravascular ablation can be matched with the guide component through the guide channel, is guided into a target blood vessel, maps cardiac muscles near the blood vessel, and can treat the technical effect of treating the myocardial of an epicardium and lesion near the blood vessel on the premise of not damaging the artery and vein blood vessels of the catheter by the high-energy pulse electric field which specifically damages the cardiac muscles at the target point position, thereby improving the path, safety and efficiency of arrhythmia operation; since the guiding channels of the first and second embodiments allow the blood to flow out of the body through the guiding channels, in the first embodiment, the first outlet 15 of the guiding channel 14 communicating with the tube 11 is disposed on the sidewall of the middle portion of the tube 11; in the second embodiment, a one-way valve 25 and a three-way component 241 are arranged at the tail part of the guide channel 24, so that the blood can not flow out of the body.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.

Claims (10)

1. An intravascular ablation pulsed electric field ablation catheter, comprising:
the electrode assembly is arranged at the end part of the tube body, and an electrode connector is arranged at the tail part of the tube body;
the electrode connector is connected with the electrode assembly through a lead arranged in the tube body and is used for controlling the electrode assembly to release a pulse electric field;
the pipe body is also provided with a guide channel for the guide assembly to pass through.
2. The intravascular ablation pulsed electric field ablation catheter of claim 1, wherein:
one end of the guide channel is communicated with the end opening of the tube body, the other end of the guide channel is arranged on the side wall of the tube body, and the guide channel is used for penetrating through a guide wire.
3. The intravascular ablation pulsed electric field ablation catheter of claim 1, wherein:
one end of the guide channel is communicated with the end opening of the tube body, the other end of the guide channel is arranged at the tail part of the tube body, and the guide channel is used for penetrating through a guide wire.
4. The pulsed electric field ablation catheter for intravascular ablation according to claim 3, wherein:
the other end of the guide channel is also provided with a one-way valve.
5. The pulsed electric field ablation catheter for intravascular ablation according to claim 4, wherein:
the other end of the guide channel is also connected with one end of a flushing pipe from the side, the other end of the flushing pipe is provided with a three-way component, and the three-way component is used for flushing heparin saline to remove air in the guide channel.
6. The intravascular ablation pulsed electric field ablation catheter of claim 1, wherein:
one end of the guide channel is communicated with the end opening of the pipe body, and the other end of the guide channel is arranged at the tail part of the pipe body;
the end of the tube body is further provided with a soft guide wire, the tail of the tube body is further provided with an operating handle for operating the soft guide wire, and the operating handle is connected with the soft guide wire through an adjusting wire arranged in the guide channel.
7. The intravascular ablation pulsed electric field ablation catheter of claim 6, wherein:
the free end of the soft guide wire is provided with a fixed bending shaping section.
8. The intravascular ablation pulsed electric field ablation catheter of any one of claims 1 to 7, wherein:
the material of the pipe body is gradually softened from the tail part to the end part of the pipe body;
and/or the presence of a gas in the gas,
the outer diameter of the pipe body is gradually reduced from the tail part to the end part.
9. The intravascular ablation pulsed electric field ablation catheter of any one of claims 1 to 7, wherein:
the electrode assembly includes first, second, third and fourth electrodes disposed at ends of the tube at equal intervals.
10. The pulsed electric field ablation catheter for intravascular ablation according to claim 9, wherein:
the first electrode, the second electrode, the third electrode, and the fourth electrode are ring-shaped electrodes.
CN202110747999.6A 2021-07-01 2021-07-01 Pulse electric field ablation catheter for intravascular ablation Pending CN113349920A (en)

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Application Number Priority Date Filing Date Title
CN202110747999.6A CN113349920A (en) 2021-07-01 2021-07-01 Pulse electric field ablation catheter for intravascular ablation

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Application Number Priority Date Filing Date Title
CN202110747999.6A CN113349920A (en) 2021-07-01 2021-07-01 Pulse electric field ablation catheter for intravascular ablation

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CN113349920A true CN113349920A (en) 2021-09-07

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113616326A (en) * 2021-09-13 2021-11-09 心航路医学科技(广州)有限公司 Pulse ablation device with saline water perfusion function
CN115153811A (en) * 2022-09-07 2022-10-11 杭州德诺电生理医疗科技有限公司 Ablation catheter and ablation system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113616326A (en) * 2021-09-13 2021-11-09 心航路医学科技(广州)有限公司 Pulse ablation device with saline water perfusion function
CN113616326B (en) * 2021-09-13 2023-03-14 心航路医学科技(广州)有限公司 Pulse ablation device with saline water perfusion function
CN115153811A (en) * 2022-09-07 2022-10-11 杭州德诺电生理医疗科技有限公司 Ablation catheter and ablation system
CN115153811B (en) * 2022-09-07 2022-12-27 杭州德诺电生理医疗科技有限公司 Ablation catheter and ablation system

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