CN115413651B - Storage device for umbilical cord blood stem cells - Google Patents

Storage device for umbilical cord blood stem cells Download PDF

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Publication number
CN115413651B
CN115413651B CN202211152227.9A CN202211152227A CN115413651B CN 115413651 B CN115413651 B CN 115413651B CN 202211152227 A CN202211152227 A CN 202211152227A CN 115413651 B CN115413651 B CN 115413651B
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CN
China
Prior art keywords
plate
cord blood
umbilical cord
rewarming
stem cells
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CN202211152227.9A
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CN115413651A (en
Inventor
刘欣伟
刘松波
项良碧
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General Hospital of Shenyang Military Region
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General Hospital of Shenyang Military Region
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0242Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/14Thermal energy storage

Abstract

The invention relates to the field of storage devices, in particular to a storage device for umbilical cord blood stem cells, which comprises a nitrogen inlet pipe, a nitrogen exhaust pipe, an end cover, an opening, a heat preservation storage tank, an electromagnetic valve and an auxiliary mechanism. According to the invention, the auxiliary mechanism is arranged in the heat preservation storage tank, and the plurality of inner cylinders and the connecting mechanism are arranged at the top of the rotating plate, so that the plurality of storage cylinders for storing umbilical cord blood stem cells can be placed in the inner cylinders for storage, so that a plurality of umbilical cord blood stem cell samples can be frozen by liquid nitrogen, meanwhile, the inner cylinders can drive the umbilical cord blood stem cells needing to be used to enter the rewarming box for water bath rewarming, the purposes of facilitating the freezing storage of a plurality of umbilical cord blood stem cells, improving the utilization rate of liquid nitrogen, reducing the waste of liquid nitrogen resources, facilitating the rewarming treatment of the umbilical cord blood stem cells, reducing the manual operation amount and improving the working efficiency are achieved.

Description

Storage device for umbilical cord blood stem cells
Technical Field
The invention relates to the field of storage devices, in particular to a storage device for umbilical cord blood stem cells.
Background
Umbilical cord blood refers to blood which is delivered from a fetus, the umbilical cord is ligated and separated, the umbilical cord blood is remained in placenta and umbilical cord, a large amount of stem cells including hematopoietic stem cells and various other stem cells are contained in the umbilical cord blood, the hematopoietic stem cells of the umbilical cord blood are collectively called as umbilical cord blood stem cells, the history of life saving of the umbilical cord blood has been 30 years, at present, a plurality of clinical researches on the aspect of regenerative medicine of the umbilical cord blood are carried out, the purpose of promoting damage repair of organism tissues and organs by using the umbilical cord blood stem cells is to better research and utilize the valuable biological resource of the umbilical cord blood, the first umbilical cord blood bank is established from the year 90 of 20 th until 2015, the umbilical cord blood bank 300 is established worldwide, the storage amount of the umbilical cord blood is estimated to be 500 ten thousand, the umbilical cord blood stem cells are stored by using a storage device, the storage device can better protect the umbilical cord blood stem cells, thereby the subsequent use of the umbilical cord blood stem cells is facilitated, the frozen blood cells are stored by adopting a freezing method, and the crude umbilical cord blood storing effect of the umbilical cord blood stem cells is better by adopting a freezing crude umbilical cord storage method.
The prior patent: CN 213293115U's a storage device for cord blood stem cells, including the shell of cuboid form, there is the cavity intermediate layer through inner bag and shell, can effectually insulate against heat, not only be convenient for add, change inside nitrogen when using, can also effectually guarantee stem cell's storage effect in addition, avoid stem cell to damage in the time of storing.
This current patent is convenient for add and change the inside liquid nitrogen of thick device that deposits, and its function is comparatively single, is inconvenient for storing many cord blood stem cells, causes the waste of liquid nitrogen resource easily, and cord blood stem cells need carry out the water bath when using simultaneously and rewarms, and this storage device does not have the rewarming function, needs the manual operation to rewarming cord blood stem cells, has increased staff's work load, has reduced work efficiency.
Disclosure of Invention
Accordingly, in order to solve the above-mentioned drawbacks, the present invention provides a storage device for umbilical cord blood stem cells to solve the above-mentioned technical problems.
In order to achieve the above purpose, the present invention adopts the following technical scheme: the utility model provides a storage device for umbilical cord blood stem cells, includes nitrogen inlet pipe, nitrogen exhaust pipe and end cover, the nitrogen inlet pipe runs through in heat preservation holding vessel outside top, the nitrogen exhaust pipe runs through in heat preservation holding vessel outside bottom, and installs the solenoid valve on nitrogen exhaust pipe and the nitrogen inlet pipe, the end cover is inseparable stretches into the opening inboard, the opening is seted up in heat preservation holding vessel top end face border department, assist mechanism sets up in heat preservation holding vessel inboard, assist mechanism includes first electric putter, inner tube, coupling mechanism, revolving plate and carriage, first electric putter installs in heat preservation holding vessel top end face middle part, and first electric putter bottom piston rod runs through in heat preservation holding vessel top end face, the inner tube passes through coupling mechanism and connects in the revolving plate, the revolving plate sets up in the carriage top, the carriage is arranged in heat preservation holding vessel inboard.
Preferably, the auxiliary mechanism further comprises a motor, a protective cover, a discharging mechanism and a rewarming mechanism, wherein the motor is arranged in the middle of the bottom end face of the sliding frame, an output shaft at the top of the motor penetrates through the bottom end face of the sliding frame and then is connected to the rotating plate, the protective cover is arranged on the bottom end face of the sliding frame, the inner side of the protective cover covers the outer side end face of the motor, the discharging mechanism is arranged at the top of the rotating plate, and the rewarming mechanism is arranged outside the heat-preserving storage tank.
Preferably, the connecting mechanism comprises a U-shaped clamping plate, a connecting hole and a cotton pad, the U-shaped clamping plate is arranged at the edge of the top end face of the rotating plate, the connecting hole is formed in the rear end of the inner side of the U-shaped clamping plate, the cotton pad is provided with two left and right end faces on the inner side of the U-shaped clamping plate, the cotton pad is adhered to the inner side of the U-shaped clamping plate, and the cotton pad is adhered to the outer end face of the inner cylinder.
Preferably, the discharging mechanism comprises a circular cylinder, a second electric push rod, a transmission plate, an electromagnet and a metal sheet, wherein the circular cylinder is rotatably arranged in the middle of the top end face of the rotary plate, the circular cylinder is connected with a piston rod at the bottom of the first electric push rod, the second electric push rod is arranged on the inner side of the circular cylinder, the piston rod on the right side of the second electric push rod penetrates through the inner ring of the circular cylinder and then is connected with the transmission plate, the transmission plate is movably embedded in the right end face of the circular cylinder, the electromagnet is embedded in the transmission plate, and the metal sheet is embedded in one end of the side surface of the inner cylinder close to the connecting hole.
Preferably, the rewarming mechanism comprises a discharge port, a sealing plate, a sliding mechanism, a rewarming box, a heating plate, a temperature sensor and a sealing rotating plate, wherein the discharge port is arranged at the middle upper part of the right end face of the heat preservation storage tank, the sealing plate is arranged at the inner side of the discharge port, the sliding mechanism is arranged at the bottom of the sealing plate, the rewarming box is arranged at the right end face of the heat preservation storage tank, the left end of the inner side of the rewarming box is connected at the inner side of the discharge port, the heating plate is arranged at the bottom of the inner side of the rewarming box, the temperature sensor is arranged at the middle lower part of the inner side of the rewarming box, and the sealing rotating plate is rotatably arranged at the top of the inner side of the rewarming box.
Preferably, the sliding mechanism comprises a sliding groove, a strip-shaped hole, a convex plate, an electric motor and a screw rod, wherein the sliding groove is arranged on the bottom end face of the inner side of the discharge port, the sliding groove is in sliding connection with the end face of the outer side of the sealing plate, the strip-shaped hole is arranged on the right end face of the sliding groove, the strip-shaped hole penetrates through the right end face of the heat-preserving storage tank, the convex plate is arranged at the bottom of the right end face of the sealing plate, the convex plate penetrates through the inner side of the strip-shaped hole, the electric motor is arranged at the bottom of the right end face of the heat-preserving storage tank, an output shaft at the top of the electric motor is connected with the screw rod, and the screw rod is in threaded fit with the inner side of the screw hole formed in the bottom end face of the convex plate.
Preferably, through holes are formed in the rotating plate and the sliding frame, and the through holes are distributed on the rotating plate and the sliding frame in an array mode.
Preferably, the right end surface of the transmission plate is in a concave arc shape, and the outer side of the transmission plate corresponds to the inner side of the connecting hole.
Preferably, the inner cylinder and the connecting mechanism are both provided with more than two edges at the top end surface of the rotating plate, and the inner cylinder and the connecting mechanism are distributed at equal intervals.
Preferably, the rewarming box is of an L-shaped structure, and a square hole matched with the discharge port is formed in the top of the left end face of the rewarming box.
The invention has the beneficial effects that:
according to the invention, the auxiliary mechanism is arranged in the heat preservation storage tank, and the plurality of inner cylinders and the connecting mechanism are arranged at the top of the rotating plate, so that the plurality of storage cylinders for storing umbilical cord blood stem cells can be placed in the inner cylinders for storage, so that a plurality of umbilical cord blood stem cell samples can be frozen by liquid nitrogen, meanwhile, the inner cylinders can drive the umbilical cord blood stem cells needing to be used to enter the rewarming box for water bath rewarming, the purposes of facilitating the freezing storage of a plurality of umbilical cord blood stem cells, improving the utilization rate of liquid nitrogen, reducing the waste of liquid nitrogen resources, facilitating the rewarming treatment of the umbilical cord blood stem cells, reducing the manual operation amount and improving the working efficiency are achieved.
According to the invention, the rotating plate is arranged on the top of the sliding frame, and the rotating plate rotates on the top of the sliding frame, so that the sliding frame can drive different inner cylinders on the top to be aligned to the discharge port, and umbilical cord blood stem cells in different inner cylinders can be discharged outwards through the discharge port to perform water bath rewarming.
According to the invention, the rewarming mechanism is arranged outside the heat preservation storage tank, the pre-stored water in the rewarming box is heated through the heating plate, and the water temperature in the rewarming box is checked through the temperature sensor, so that the water in the rewarming box is convenient for carrying out water bath rewarming treatment on the umbilical cord blood stem cells in the inner barrel.
Through holes are formed in the rotating plate and the sliding frame, and are distributed on the rotating plate and the sliding frame in an array mode, so that external liquid nitrogen can flow downwards when the rotating plate and the sliding frame move upwards.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic elevational cross-sectional view of the assist mechanism of the present invention;
FIG. 3 is a schematic view of the structure of the connecting mechanism of the present invention;
FIG. 4 is a schematic top view of the discharge mechanism of the present invention;
FIG. 5 is a schematic view of a sheet metal connecting structure of the present invention;
FIG. 6 is a schematic diagram of a drive plate connection structure of the present invention;
FIG. 7 is a schematic diagram of a front sectional structure of a rewarming mechanism of the present invention;
fig. 8 is an enlarged schematic view of the structure of fig. 7 a according to the present invention.
Wherein: the nitrogen inlet pipe-1, the nitrogen outlet pipe-2, the end cover-3, the opening-4, the heat preservation storage tank-5, the electromagnetic valve-6, the auxiliary mechanism-7, the first electric push rod-71, the inner cylinder-72, the connecting mechanism-73, the rotating plate-74, the sliding frame-75, the motor-76, the protection cover-77, the discharging mechanism-78, the rewarming mechanism-79, the U-shaped clamping plate-731, the connecting hole-732, the cotton pad-733, the round cylinder-781, the second electric push rod-782, the transmission plate-783, the electromagnet-784, the metal sheet-785, the discharging port-791, the sealing plate-792, the sliding mechanism-793, the rewarming box-794, the heating plate-795, the temperature sensor-796, the sealing rotating plate-797, the sliding groove-7931, the strip hole-7932, the convex plate-7933, the electric motor-7934 and the screw-7935.
Detailed Description
In order to further explain the technical scheme of the invention, the following is explained in detail through specific examples.
As shown in fig. 1, the invention provides a storage device for umbilical cord blood stem cells, which comprises a nitrogen inlet pipe 1, a nitrogen discharge pipe 2 and an end cover 3, wherein the nitrogen inlet pipe 1 penetrates through the top of the outer side of a heat preservation storage tank 5, the nitrogen discharge pipe 2 penetrates through the bottom of the outer side of the heat preservation storage tank 5, electromagnetic valves 6 are arranged on the nitrogen discharge pipe 2 and the nitrogen inlet pipe 1, the end cover 3 tightly stretches into the inner side of an opening 4, and the opening 4 is arranged at the edge of the top end surface of the heat preservation storage tank 5;
specifically, the end cover 3 can be pulled to be separated from the inner side of the opening 4, the storage barrel storing the umbilical cord blood stem cells is placed on the inner side of the inner barrel 72, then the end cover 3 is inserted into the inner side of the opening 4 to seal the heat preservation storage tank 5, meanwhile, external frozen liquid nitrogen can be led into the heat preservation storage tank 5 by opening the electromagnetic valve 6 on the nitrogen inlet pipe 1, so that the liquid nitrogen can freeze the inner barrel 72 after entering the heat preservation storage tank 5, the storage barrel in the inner barrel 72 and the umbilical cord blood stem cells in the storage barrel can be frozen, thereby realizing the frozen storage of the umbilical cord blood stem cells, and the liquid nitrogen in the heat preservation storage tank 5 can be discharged by opening the electromagnetic valve 6 on the nitrogen discharge pipe 2, thereby being convenient for replacing the liquid nitrogen in the heat preservation storage tank 5.
As shown in fig. 2, in this embodiment, the auxiliary mechanism 7 is disposed inside the thermal insulation storage tank 5, the auxiliary mechanism 7 includes a first electric push rod 71, an inner cylinder 72, a connection mechanism 73, a rotating plate 74 and a sliding frame 75, the first electric push rod 71 is locked and fixed in the middle of the top surface of the thermal insulation storage tank 5, a piston rod at the bottom of the first electric push rod 71 penetrates through the top surface of the thermal insulation storage tank 5, the first electric push rod 71 is connected to the circular cylinder 781 to drive the circular cylinder 781 to move vertically, the inner cylinder 72 is connected to the rotating plate 74 through the connection mechanism 73, and is used for positioning the storage cylinder in which the umbilical cord blood stem cells are disposed, the rotating plate 74 is rotatably mounted at the top of the sliding frame 75, the rotating plate 74 can rotate horizontally at the top of the sliding frame 75, and the sliding frame 75 is slidably mounted at the inner side of the thermal insulation storage tank 5, and the sliding frame 75 can move vertically in the thermal insulation storage tank 5 to drive the umbilical cord blood stem cells to move vertically;
the auxiliary mechanism 7 further comprises a motor 76, a protective cover 77, a discharge mechanism 78 and a rewarming mechanism 79, wherein the motor 76 is locked and fixed in the middle of the bottom end surface of the sliding frame 75, an output shaft at the top of the motor 76 penetrates through the bottom end surface of the sliding frame 75 and then is connected to the middle of the bottom end surface of the rotating plate 74, the motor 76 is started to drive the rotating plate 74 to horizontally rotate at the top of the sliding frame 75, the protective cover 77 is locked and fixed on the bottom end surface of the sliding frame 75, the inner side of the protective cover 77 covers the end surface at the outer side of the motor 76 and is used for protecting the motor 76, the discharge mechanism 78 is arranged at the top of the rotating plate 74, and the rewarming mechanism 79 is arranged at the outer side of the thermal insulation storage tank 5 and is used for rewarming umbilical cord blood stem cells;
wherein through holes are formed on the rotating plate 74 and the sliding frame 75, and the through holes are distributed on the rotating plate 74 and the sliding frame 75 in an array manner, so that liquid nitrogen is prevented from moving upwards when the rotating plate 74 and the sliding frame 75 vertically move;
the inner cylinder 72 and the connecting mechanism 73 are respectively provided with more than two rotating plates 74 at the top end surface edge, and the inner cylinder 72 and the connecting mechanism 73 are distributed at equal intervals, so that a plurality of umbilical cord blood stem cells can be stored conveniently;
specifically, the inner cylinder 72 is driven to move vertically when moving vertically in the thermal insulation storage tank 5 by the carriage 75, and the inner cylinder 72 drives the storage cylinder storing umbilical cord blood stem cells therein to move downward into the thermal insulation storage tank 5 for freezing storage.
As shown in fig. 3, the connecting mechanism 73 in this embodiment includes a U-shaped clamping plate 731, a connecting hole 732 and a cotton pad 733, wherein the U-shaped clamping plate 731 is vertically welded at the edge of the top end surface of the rotating plate 74, the U-shaped clamping plate 731 is attached to the outer end surface of the inner cylinder 72 for providing auxiliary supporting force to the inner cylinder 72, the connecting hole 732 is opened at the rear end of the inner side of the U-shaped clamping plate 731, the cotton pad 733 is provided with two left and right end surfaces on the inner side of the U-shaped clamping plate 731, the cotton pad 733 is attached to the inner side of the U-shaped clamping plate 731, and the cotton pad 733 is attached to the outer end surface of the inner cylinder 72 for limiting the outer side of the inner cylinder 72;
in the embodiment, the cotton pad 733 is made of sponge material, which has better elasticity;
in the embodiment, the first electric push rod 71, the motor 76, the second electric push rod 782, the electromagnet 784, the heating plate 795 and the temperature sensor 796 are connected to an external Programmable Logic Controller (PLC), so that programming control on electric equipment on the device is facilitated;
specifically, the storage cylinder inside the inner cylinder 72 provides clamping support force for the inner cylinder 72 through the U-shaped clamping plate 731 when storing umbilical cord blood stem cells, and further improves the stability of the placement process of the inner cylinder 72 through the cotton pads 733.
As shown in fig. 4 to 6, the discharging mechanism 78 in this embodiment includes a circular cylinder 781, a second electric push rod 782, a driving plate 783, an electromagnet 784 and a metal sheet 785, the circular cylinder 781 is rotatably mounted in the middle of the top end surface of the rotating plate 74, and the circular cylinder 781 is connected with a piston rod at the bottom of the first electric push rod 71, the first electric push rod 71 can drive the circular cylinder 781 to move vertically, meanwhile, the rotating plate 74 can rotate horizontally at the bottom of the circular cylinder 781, the second electric push rod 782 is mounted inside the circular cylinder 781, and a piston rod at the right side of the second electric push rod 782 is connected with the driving plate 783 after passing through the inner ring of the circular cylinder 781, for driving the driving plate 783 to move horizontally, the driving plate 783 is movably embedded in the right end surface of the circular cylinder 781, the electromagnet 784 is embedded in the driving plate 783 after passing through the inner side of the circular cylinder 783, and the metal sheet 785 is fixed on the side surface of the inner cylinder 72 near one end of the connecting hole 732 for driving the inner cylinder 72 to move horizontally;
in the embodiment, the right end surface of the driving plate 783 is in a concave arc shape, and the outer side of the driving plate 783 corresponds to the inner side of the connecting hole 732, so that the driving plate 783 is stably attached to the metal sheet 785;
in the embodiment, the metal sheet 785 is made of stainless steel, so that the corrosion resistance is better;
specifically, the motor 76 drives the rotating plate 74 to horizontally rotate, the rotating plate 74 drives the inner cylinder 72 at the top to rotate, the inner cylinder 72 drives the storage cylinder storing umbilical cord blood stem cells to rotate, the rotating plate 74 drives the connecting hole 732 to horizontally rotate, when the connecting hole 732 is aligned with the driving plate 783, the second electric push rod 782 is started to drive the driving plate 783 and the electromagnet 784 to horizontally move, and the electromagnet 784 is started to generate magnetic force to apply suction force to the metal sheet 785, so that the metal sheet 785 is tightly attached to the driving plate 783, and the second electric push rod 782 is convenient to drive the inner cylinder 72 to horizontally move while driving the driving plate 783 to horizontally move
As shown in fig. 7, the rewarming mechanism 79 in this embodiment includes a discharge port 791, a sealing plate 792, a sliding mechanism 793, a rewarming box 794, a heating plate 795, a temperature sensor 796 and a sealing rotating plate 797, the discharge port 791 is vertically opened at the middle upper part of the right end face of the insulated storage tank 5, the discharge port 791 corresponds to the inner cylinder 72 for the inner cylinder 72 to be discharged outwards through the discharge port 791, and the sealing plate 792 is provided at the inner side of the discharge port 791 for sealing the discharge port 791;
the sliding mechanism 793 is arranged at the bottom of the sealing plate 792 and used for driving the sealing plate 792 to vertically move, the rewiring box 794 is arranged on the right end face of the heat preservation storage tank 5, the left end of the inner side of the rewiring box 794 is connected with the inner side of the exhaust port 791, the heating plate 795 is locked and fixed at the bottom of the inner side of the rewiring box 794 and used for heating water in the rewiring box 794, the temperature sensor 796 is locked and fixed at the middle lower part of the inner side of the rewiring box 794 and used for detecting the water temperature in the rewiring box 794, and the sealing rotating plate 797 is rotatably arranged at the top of the inner side of the rewiring box 794;
the rewarming box 794 is of an L-shaped structure, and a square hole matched with the exhaust port 791 is formed in the top of the left end face of the rewarming box 794, so that the inner cylinder 72 can conveniently enter the rewarming box 794 after passing through the exhaust port 791;
specifically, the water pre-stored in the rewarming box 794 is heated by starting the heating plate 795, the water temperature in the rewarming box 794 is detected by the temperature sensor 796, the water temperature is controlled to be about 41 ℃, then the circular cylinder 781 is driven to move upwards by starting the first electric push rod 71, the rotary plate 74, the sliding frame 75 and the inner cylinder 72 are driven to move upwards by the circular cylinder 781, when the inner cylinder 72 moves towards the outlet 791, the second electric push rod 782 drives the inner cylinder 72 to move rightwards, the inner cylinder 72 moves rightwards to pass through the outlet 791 and then enters the rewarming box 794, the electromagnet 784 is powered off, the inner cylinder 72 drives the internal storage cylinder and the umbilical cord blood stem cells to move downwards to enter the rewarming box 794 under the action of gravity, so that the umbilical cord blood stem cells are rewarmed in the rewarming box 794, the sealing rotary plate 797 is pulled upwards after the rewarming is finished, the inner cylinder 72 is pulled outwards, and the umbilical cord blood stem cells in the inner cylinder 72 are used.
As shown in fig. 8, the sliding mechanism 793 in this embodiment includes a sliding slot 7931, a bar-shaped hole 7932, a protruding plate 7933, an electric motor 7934 and a screw 7935, wherein the sliding slot 7931 is vertically opened at the bottom end surface of the inner side of the outlet 791, the sliding slot 7931 is slidably connected with the end surface of the outer side of the sealing plate 792, the sealing plate 792 can vertically slide inside the sliding slot 7931, the bar-shaped hole 7932 is opened at the right end surface of the inner side of the sliding slot 7931, and the bar-shaped hole 7932 penetrates through the right end surface of the thermal insulation storage tank 5;
the protruding plate 7933 is arranged at the bottom of the right end face of the sealing plate 792, the protruding plate 7933 penetrates through the inner side of the strip-shaped hole 7932, the protruding plate 7933 can vertically move inside the strip-shaped hole 7932, the electric motor 7934 is locked and fixed at the bottom of the right end face of the heat-preserving storage tank 5, the output shaft at the top of the electric motor 7934 is connected with the screw rod 7935 and used for driving the screw rod 7935 to rotate, the screw rod 7935 is in threaded fit with the inner side of a screw hole formed in the bottom end face of the protruding plate 7933, and the screw rod 7935 is matched with the screw hole when being rotated so as to drive the protruding plate 7933 to vertically move;
specifically, the electric motor 7934 is started to drive the screw 7935 to rotate, the screw 7935 is matched with the screw hole on the convex plate 7933 in the rotation process of the screw 7935 to drive the convex plate 7933 to vertically move along the strip-shaped hole 7932, and the convex plate 7933 drives the sealing plate 792 to vertically move to seal the discharge port 791, so that liquid nitrogen in the heat-insulation storage tank 5 is prevented from leaking.
The foregoing is merely a preferred example of the present invention, and the present invention is not limited thereto, but it is to be understood that modifications and equivalents of some of the technical features described in the foregoing embodiments may be made by those skilled in the art, although the present invention has been described in detail with reference to the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. The utility model provides a storage device for umbilical cord blood stem cells, includes advances nitrogen pipe (1), nitrogen exhaust pipe (2) and end cover (3), advance nitrogen pipe (1) and run through in heat preservation holding vessel (5) outside top, nitrogen exhaust pipe (2) run through in heat preservation holding vessel (5) outside bottom, and install solenoid valve (6) on nitrogen exhaust pipe (2) and the nitrogen intake pipe (1), end cover (3) closely stretch into opening (4) inboard, opening (4) are seted up in heat preservation holding vessel (5) top face border department;
the method is characterized in that: the heat preservation storage tank is characterized by further comprising an auxiliary mechanism (7), the auxiliary mechanism (7) is arranged on the inner side of the heat preservation storage tank (5), the auxiliary mechanism (7) comprises a first electric push rod (71), an inner cylinder (72), a connecting mechanism (73), a rotating plate (74) and a sliding frame (79), the first electric push rod (71) is arranged in the middle of the top end surface of the heat preservation storage tank (5), a piston rod at the bottom of the first electric push rod (71) penetrates through the top end surface of the heat preservation storage tank (5), the inner cylinder (72) is connected to the rotating plate (74) through the connecting mechanism (73), the rotating plate (74) is arranged on the top of the sliding frame (75), the sliding frame (75) is arranged on the inner side of the heat preservation storage tank (5), the auxiliary mechanism (7) further comprises a motor (76), a protecting cover (77), a discharging mechanism (78) and a re-heating mechanism (79), the motor (76) is arranged in the middle of the bottom end surface of the sliding frame (75), an output shaft at the top of the motor (76) penetrates through the bottom end surface of the sliding frame (75) and then is connected to the rotating plate (74), the protecting cover (77) is arranged on the bottom end surface of the inner side of the sliding frame (75), the temperature restoring mechanism (79) is arranged outside the heat preservation storage tank (5), the connecting mechanism (73) comprises a U-shaped clamping plate (731), a connecting hole (732) and a cotton pad (733), the U-shaped clamping plate (731) is arranged at the edge of the top end surface of the rotating plate (74), the connecting hole (732) is arranged at the inner side rear end of the U-shaped clamping plate (731), the cotton pad (733) is provided with two inner side left and right end surfaces of the U-shaped clamping plate (731), the cotton pad (733) is adhered to the inner side of the U-shaped clamping plate (731), the cotton pad (733) is attached to the outer side end surface of the inner cylinder (72), the discharging mechanism (78) comprises a circular cylinder (781), a second electric push rod (782), a transmission plate (783), an electromagnet (784) and a metal sheet (785), the circular cylinder (781) is rotatably arranged at the middle of the top end surface of the rotating plate (74), the circular cylinder (781) is connected with the bottom of the first electric push rod (71), the second electric push rod (783) is arranged at the inner side of the rotating plate (783) and penetrates through the inner side of the circular cylinder (783) to the inner ring (783), the utility model provides a temperature control device for a solar heat collection device, including inner tube (72), connecting hole (732) are close to in metal sheet (785), rewarming mechanism (79) are close to connecting hole (79) one end, rewarming mechanism (79) are including discharge port (791), closing plate (792), slide mechanism (793), rewarming box (794), hot plate (795), temperature sensor (796) and sealed rotating plate (797), discharge port (791) are seted up in upper portion in heat preservation holding vessel (5) right-hand member face, closing plate (792) set up in discharge port (791) inboard, slide mechanism (793) set up in closing plate (792) bottom, rewarming box (794) are installed in heat preservation holding vessel (5) right-hand member face, and rewarming box (794) inboard left end links up in discharge port (791) inboard, heating plate (795) are installed in rewarming box (794) inboard bottom, temperature sensor (796) are installed in the inboard lower part of rewarming box (794), sealed rotating plate (797) rotate and install in interior side (794).
2. A storage device for umbilical cord blood stem cells as claimed in claim 1 wherein: slide mechanism (793) include spout (7931), bar hole (7932), raised plate (7933), electric motor (7934) and screw rod (7935), spout (7931) are seted up in the inboard bottom surface of discharge port (791), and spout (7931) and closing plate (792) outside terminal surface sliding connection, bar hole (7932) are seted up in spout (7931) inboard right-hand member face, and bar hole (7932) run through in heat preservation holding vessel (5) right-hand member face, raised plate (7933) set up in closing plate (792) right-hand member face bottom, and raised plate (7933) run through in bar hole (7932) inboard, electric motor (7934) are installed in heat preservation holding vessel (5) right-hand member face bottom, and electric motor (7934) top output shaft is connected with screw rod (7935), screw rod (7935) and the inboard screw thread fit of screw hole that raised plate (7933) bottom face was seted up.
3. A storage device for umbilical cord blood stem cells as claimed in claim 1 wherein: through holes are formed in the rotating plate (74) and the sliding frame (75), and the through holes are distributed on the rotating plate (74) and the sliding frame (75) in an array mode.
4. A storage device for umbilical cord blood stem cells as claimed in claim 1 wherein: the right end face of the transmission plate (783) is in a concave arc shape, and the outer side of the transmission plate (783) corresponds to the inner side of the connecting hole (732).
5. A storage device for umbilical cord blood stem cells as claimed in claim 1 wherein: the inner cylinder (72) and the connecting mechanism (73) are respectively provided with more than two edges at the top end surface of the rotating plate (74), and the inner cylinder (72) and the connecting mechanism (73) are distributed at equal intervals.
6. A storage device for umbilical cord blood stem cells as claimed in claim 1 wherein: the rewarming box (794) is of an L-shaped structure, and a square hole matched with the exhaust port (791) is formed in the top of the left end face of the rewarming box (794).
CN202211152227.9A 2022-09-21 2022-09-21 Storage device for umbilical cord blood stem cells Active CN115413651B (en)

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