CN115400280A - Double-chamber blood flow regulator for ECMO - Google Patents
Double-chamber blood flow regulator for ECMO Download PDFInfo
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- CN115400280A CN115400280A CN202211063302.4A CN202211063302A CN115400280A CN 115400280 A CN115400280 A CN 115400280A CN 202211063302 A CN202211063302 A CN 202211063302A CN 115400280 A CN115400280 A CN 115400280A
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- ecmo
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- tube
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- 230000017531 blood circulation Effects 0.000 title claims abstract description 20
- 238000002618 extracorporeal membrane oxygenation Methods 0.000 title claims abstract description 19
- 239000008280 blood Substances 0.000 claims abstract description 54
- 210000004369 blood Anatomy 0.000 claims abstract description 54
- 210000005246 left atrium Anatomy 0.000 claims abstract description 12
- 230000008334 biventricular blood circulation Effects 0.000 claims abstract description 3
- 210000005245 right atrium Anatomy 0.000 claims description 6
- 210000001631 vena cava inferior Anatomy 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 4
- 210000002620 vena cava superior Anatomy 0.000 claims description 3
- 206010037423 Pulmonary oedema Diseases 0.000 abstract description 3
- 208000005333 pulmonary edema Diseases 0.000 abstract description 3
- 206010013012 Dilatation ventricular Diseases 0.000 abstract description 2
- 230000036723 left ventricular dilatation Effects 0.000 abstract description 2
- 210000004204 blood vessel Anatomy 0.000 description 4
- 230000004217 heart function Effects 0.000 description 4
- 238000006213 oxygenation reaction Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 210000004971 interatrial septum Anatomy 0.000 description 3
- 230000002861 ventricular Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 206010053648 Vascular occlusion Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001746 atrial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000001706 oxygenating effect Effects 0.000 description 1
- 230000036316 preload Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 230000004202 respiratory function Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 210000005241 right ventricle Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a biventricular blood flow regulator for ECMO (enhanced multiorifice), and relates to the technical field of medical instruments. The device comprises a flow regulator, wherein one end of the flow regulator is provided with a first blood leading tube and a second blood leading tube, the other end of the flow regulator is provided with an eduction tube, one end of the eduction tube is provided with a centrifugal pump, a plurality of measuring holes are formed in the first blood leading tube and the second blood leading tube, and the measuring holes correspond to the flow regulator. According to the invention, the first blood leading tube is arranged, and the blood in the left atrium is drained through the first blood leading tube, so that the left heart pressure can be relieved, and complications such as left heart expansion, left ventricular dilatation and pulmonary edema can be prevented; through setting up flow regulator, flow regulator adjusts blood flow and blood velocity of flow, can individuation adjust the blood flow of biventricular drainage, realizes accurate blood flow control.
Description
Technical Field
The invention belongs to the technical field of medical appliances, and particularly relates to a double-chamber blood flow regulator for ECMO.
Background
The ECMO mainly comprises an intravascular cannula, a connecting tube, a power pump, an oxygenator, an oxygen supply tube, a monitoring system and the like, wherein the power pump provides power to drive blood to flow in a pipeline; the oxygenator is used for oxygenating the input blood and outputting oxygenated arterial blood.
Currently, an extracorporeal membrane lung oxygenation technology used clinically is widely applied to support treatment of patients with severe circulation or respiratory failure and the like, but venous blood is drained from a right heart system to the outside of a body in the existing treatment, and although the effect of reducing the right ventricular preload can be achieved, cardiac function and respiratory function insufficiency are assisted to be treated, when blood treated by ECMO is perfused back to the human body again, left ventricular afterload can be increased, and then left ventricular expansion and left atrial pressure rise, cardiac insufficiency, pulmonary edema and the like are aggravated, and the recovery of the left cardiac function is finally influenced.
The existing clinically common solution is that the ECMO treatment is combined with additional treatment measures, including IABP, interatrial septum fistulation and the like, although the method can better relieve the pressure of the left heart system, the method inevitably brings about secondary operation and increases the treatment cost.
Therefore, it is necessary to design a device for relieving the pressure in the left atrium, and the device is also necessary to flexibly adjust the blood flow of the bi-atrial drainage according to the oxygenation condition and the cardiac function condition of the patient.
Disclosure of Invention
The invention aims to provide a biventricular blood flow regulator for ECMO (interstitial cardiac vascular occlusion), which solves the technical problems that after the existing ECMO treatment, the pressure of the left atrium is reduced, a secondary operation is required, and the blood flow volume of biventricular drainage cannot be flexibly regulated.
In order to achieve the purpose, the invention is realized by the following technical scheme:
the utility model provides a two room blood flow regulators for ECMO, includes flow regulator, flow regulator's one end has been installed first and has been drawn blood vessel and second and draw blood vessel, the stand pipe has been installed to flow regulator's the other end, the centrifugal pump has been installed to the one end of stand pipe, first draw blood vessel with the second draws and all has seted up a plurality of measuring holes in the blood vessel, just the measuring hole with flow regulator is corresponding.
Optionally, the flow regulator corresponds to the centrifugal pump and the flow regulator corresponds to blood flow inside the left atrium and the right atrium.
Optionally, the first blood guiding vessel corresponds to the left atrium, the second blood guiding vessel corresponds to the right atrium, the first blood guiding vessel corresponds to the inferior vena cava, the second blood guiding vessel corresponds to the superior vena cava, and the first blood guiding vessel passes through the inferior vena cava and then enters the left atrium through the interatrial septum puncture technique.
Optionally, the plurality of measuring holes are uniformly distributed at one end and the tube wall of the first blood guiding tube and the second blood guiding tube.
The embodiment of the invention has the following beneficial effects:
according to the embodiment of the invention, the first blood leading tube is arranged, and blood in the left atrium is drained through the first blood leading tube, so that the left heart pressure can be relieved, and complications such as left heart expansion, left ventricular dilatation and pulmonary edema can be prevented; through setting up flow regulator, flow regulator adjusts blood flow and blood velocity of flow, can individualize the blood flow of adjusting biventricular drainage, realizes accurate blood flow control.
Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the invention and, together with the description, serve to explain the invention and not to limit the invention. In the drawings:
FIG. 1 is a perspective view of a first blood introducing tube and a second blood introducing tube assembled according to an embodiment of the present invention;
FIG. 2 is a schematic sectional view of the first blood introducing tube, the second blood introducing tube and the heart assembled according to one embodiment of the present invention;
fig. 3 is a perspective view illustrating an assembly of a flow regulator and a centrifugal pump according to an embodiment of the present invention.
Wherein the figures include the following reference numerals:
the device comprises a flow regulator 1, a first blood leading pipe 2, a second blood leading pipe 3, a leading-out pipe 4, a measuring hole 5 and a centrifugal pump 6.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses.
In order to keep the following description of the embodiments of the invention clear and concise, a detailed description of known functions and known parts of the invention is omitted.
Referring to fig. 1-3, in one embodiment, a bi-atrial blood flow regulator for ECMO is provided, comprising: the blood flow regulator 1 can flexibly regulate the blood flow of the first blood guiding tube 2 and the second blood guiding tube 3 according to the oxygenation state, the cardiac function and other indexes of a patient.
The first blood leading tube 2 is inserted into the left atrium from the inferior vena cava through an interatrial septum puncture technology to drain blood in the left atrium, and the second blood leading tube 3 is inserted into the right atrium from the superior vena cava to drain blood in the right atrium.
The flow regulator 1 is used as follows: the heart rhythm (usually the waveform of an electrocardiographic signal) is monitored, which can be continuously captured by data acquisition and is then amplified by an algorithm to detect the time at which the heart begins to contract (i.e., the R-wave). The flow regulator 1 is braked and closed in accordance with the steep rise and fall of the square wave over a time sequence, respectively. The point in time of braking or closing for each flow regulator 1 is trigger-timed with respect to the R-wave. The magnitude of the time delay with respect to the R-wave is a predetermined control input parameter.
There is also a need for monitoring other conditions of the patient, such as: the control variables determining the state of oxygenation for the braking and the closing of the flow regulator 1 are used entirely or only partially. The determination of the recirculation can be carried out using a biomimetic cycle test bench experiment or an animal experiment, and the optimal control time point for reducing the recirculation rate can be found as a control input parameter through repeated experiments, and is realized in the invention.
In one embodiment of the present invention, the flow regulator 1 is connected to the centrifugal pump 6, a heart rate sensor capable of receiving signals indicative of heart rate, and a controller capable of generating control commands according to the set control logic and the sensed heart rate signals. The control logic is optimized to allow the heart to perfuse a maximum amount of oxygenated blood into the right ventricle during diastole and to pump a maximum amount of venous return deoxygenated blood into the ECMO circuit during systole.
Furthermore, in order to improve the efficiency of blood drainage, the measuring holes 5 are uniformly distributed at the ends and the tube wall of the first blood guiding tube 2 and the second blood guiding tube 3.
Further, in order to provide power to drive the blood to flow in the first blood introducing pipe 2 and the second blood introducing pipe 3, an outlet pipe 4 is installed at the other end of the flow regulator 1, and then a centrifugal pump 6 is installed at one end of the outlet pipe 4, so that the blood can be driven to flow in the first blood introducing pipe 2 and the second blood introducing pipe 3 by the centrifugal pump 6.
It should be noted that all the electric devices referred to in this application may be powered by a storage battery or an external power source.
The above embodiments may be combined with each other.
It should be noted that the terms "first," "second," and the like in the description and claims of this application and in the accompanying drawings are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used is interchangeable under appropriate circumstances such that the embodiments of the application described herein are capable of operation in sequences other than those illustrated or described herein.
In the description of the present invention, it is to be understood that the directions or positional relationships indicated by the directional terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal" and "top, bottom", etc., are generally based on the directions or positional relationships shown in the drawings, and are for convenience of description and simplicity of description only, and in the case of not making a reverse description, these directional terms do not indicate and imply that the device or element referred to must have a particular orientation or be constructed and operated in a particular orientation, and therefore, should not be considered as limiting the scope of the present invention; the terms "inner and outer" refer to the inner and outer relative to the profile of the respective component itself.
Claims (7)
1. A double-chamber blood flow regulator for ECMO comprises a flow regulator (1) positioned on one side of the heart, and is characterized in that one end of the flow regulator (1) is provided with a first blood leading pipe (2) and a second blood leading pipe (3), the other end of the flow regulator (1) is provided with an outlet pipe (4), and one end of the outlet pipe (4) is provided with a centrifugal pump (6);
a plurality of measuring holes (5) are formed in the first blood guiding pipe (2) and the second blood guiding pipe (3), and the measuring holes (5) correspond to the flow regulator (1).
2. A bi-atrial flow regulator for ECMO according to claim 1, wherein said flow regulator (1) corresponds to said centrifugal pump (6).
3. A bi-atrial blood flow regulator for ECMO according to claim 1, wherein the flow regulator (1) corresponds to the blood flow inside the left atrium and the right atrium.
4. A bi-atrial flow regulator for ECMO as claimed in claim 1, wherein the first blood introduction tube (2) corresponds to the left atrium and the second blood introduction tube (3) corresponds to the right atrium.
5. A biventricular blood flow regulator for ECMO according to claim 1, wherein the first drainage vessel (2) corresponds to the inferior vena cava and the second drainage vessel (3) corresponds to the superior vena cava.
6. A bi-atrial flow regulator for ECMO as claimed in claim 1, wherein the first drainage vessel (2) passes through the inferior vena cava and into the left atrium by a transseptal puncture technique.
7. A flow regulator for the biliaryotic blood flow for ECMO according to claim 1, characterized in that said plurality of measuring holes (5) are uniformly distributed at one end and at the vessel wall of said first (2) and said second (3) blood lead-through.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211063302.4A CN115400280A (en) | 2022-09-01 | 2022-09-01 | Double-chamber blood flow regulator for ECMO |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211063302.4A CN115400280A (en) | 2022-09-01 | 2022-09-01 | Double-chamber blood flow regulator for ECMO |
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| Publication Number | Publication Date |
|---|---|
| CN115400280A true CN115400280A (en) | 2022-11-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202211063302.4A Pending CN115400280A (en) | 2022-09-01 | 2022-09-01 | Double-chamber blood flow regulator for ECMO |
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Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681789A1 (en) * | 1991-09-30 | 1993-04-02 | Nippon Zeon Co | Apparatus for circulatory assistance |
| RU2526880C1 (en) * | 2013-06-14 | 2014-08-27 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Method for haemodynamic left ventricular unload in peripheral venoarterial extracorporeal membrane oxygenation |
| CN106659840A (en) * | 2014-08-20 | 2017-05-10 | 泉工医科工业株式会社 | Blood circulation system |
| CN109414539A (en) * | 2016-07-12 | 2019-03-01 | 怡忠科技股份有限公司 | Extracorporeal life supports system |
| CN109793978A (en) * | 2019-03-28 | 2019-05-24 | 吉林大学 | A kind of left heart drainage-tube with survey pressure and negative pressure stabilized function |
| CN213698242U (en) * | 2020-10-10 | 2021-07-16 | 清远市人民医院 | ECMO and CRRT pipeline with current limiter |
| CN113384764A (en) * | 2021-06-04 | 2021-09-14 | 中国医学科学院阜外医院深圳医院(深圳市孙逸仙心血管医院) | Extracorporeal membrane pulmonary oxygenation cannula for transatrial septum |
| CN214911072U (en) * | 2020-12-16 | 2021-11-30 | 江苏省苏北人民医院 | Brain hematoma drainage device |
| CN214911434U (en) * | 2020-12-14 | 2021-11-30 | 天津市第三中心医院 | Be applied to left heart decompression pipeline and pressure measurement subassembly of ECMO pipeline |
| CN113750309A (en) * | 2021-09-14 | 2021-12-07 | 上海科尔夫医疗科技有限公司 | Percutaneous intervention catheter type ventricular assist device |
| CN215938512U (en) * | 2021-06-09 | 2022-03-04 | 武汉大学中南医院 | Controllable flow Y-shaped tube for extracorporeal membrane pulmonary oxygen therapy |
| CN217015039U (en) * | 2021-11-26 | 2022-07-22 | 浙江首沃医疗科技有限公司 | Transfemoral vein left atrium drainage tube |
-
2022
- 2022-09-01 CN CN202211063302.4A patent/CN115400280A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681789A1 (en) * | 1991-09-30 | 1993-04-02 | Nippon Zeon Co | Apparatus for circulatory assistance |
| RU2526880C1 (en) * | 2013-06-14 | 2014-08-27 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Method for haemodynamic left ventricular unload in peripheral venoarterial extracorporeal membrane oxygenation |
| CN106659840A (en) * | 2014-08-20 | 2017-05-10 | 泉工医科工业株式会社 | Blood circulation system |
| CN109414539A (en) * | 2016-07-12 | 2019-03-01 | 怡忠科技股份有限公司 | Extracorporeal life supports system |
| CN109793978A (en) * | 2019-03-28 | 2019-05-24 | 吉林大学 | A kind of left heart drainage-tube with survey pressure and negative pressure stabilized function |
| CN213698242U (en) * | 2020-10-10 | 2021-07-16 | 清远市人民医院 | ECMO and CRRT pipeline with current limiter |
| CN214911434U (en) * | 2020-12-14 | 2021-11-30 | 天津市第三中心医院 | Be applied to left heart decompression pipeline and pressure measurement subassembly of ECMO pipeline |
| CN214911072U (en) * | 2020-12-16 | 2021-11-30 | 江苏省苏北人民医院 | Brain hematoma drainage device |
| CN113384764A (en) * | 2021-06-04 | 2021-09-14 | 中国医学科学院阜外医院深圳医院(深圳市孙逸仙心血管医院) | Extracorporeal membrane pulmonary oxygenation cannula for transatrial septum |
| CN215938512U (en) * | 2021-06-09 | 2022-03-04 | 武汉大学中南医院 | Controllable flow Y-shaped tube for extracorporeal membrane pulmonary oxygen therapy |
| CN113750309A (en) * | 2021-09-14 | 2021-12-07 | 上海科尔夫医疗科技有限公司 | Percutaneous intervention catheter type ventricular assist device |
| CN217015039U (en) * | 2021-11-26 | 2022-07-22 | 浙江首沃医疗科技有限公司 | Transfemoral vein left atrium drainage tube |
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