CN115361958A - 使用间充质谱系前体或干细胞治疗炎症性肺病的方法 - Google Patents

使用间充质谱系前体或干细胞治疗炎症性肺病的方法 Download PDF

Info

Publication number
CN115361958A
CN115361958A CN202180026562.1A CN202180026562A CN115361958A CN 115361958 A CN115361958 A CN 115361958A CN 202180026562 A CN202180026562 A CN 202180026562A CN 115361958 A CN115361958 A CN 115361958A
Authority
CN
China
Prior art keywords
cells
subject
stem cells
mesenchymal lineage
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180026562.1A
Other languages
English (en)
Chinese (zh)
Inventor
S·伊茨库
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mesoblast International SARL
Original Assignee
Mesoblast International SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2020900685A external-priority patent/AU2020900685A0/en
Application filed by Mesoblast International SARL filed Critical Mesoblast International SARL
Publication of CN115361958A publication Critical patent/CN115361958A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CN202180026562.1A 2020-03-05 2021-03-04 使用间充质谱系前体或干细胞治疗炎症性肺病的方法 Pending CN115361958A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2020900685 2020-03-05
AU2020900685A AU2020900685A0 (en) 2020-03-05 Method for treating inflammatory lung diseases using mesenchymal lineage precursor or stem cells
PCT/EP2021/055483 WO2021176001A1 (en) 2020-03-05 2021-03-04 Method for treating inflammatory lung diseases using mesenchymal lineage precursor or stem cells

Publications (1)

Publication Number Publication Date
CN115361958A true CN115361958A (zh) 2022-11-18

Family

ID=74867509

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180026562.1A Pending CN115361958A (zh) 2020-03-05 2021-03-04 使用间充质谱系前体或干细胞治疗炎症性肺病的方法

Country Status (9)

Country Link
US (1) US20230293589A1 (https=)
EP (1) EP4114418A1 (https=)
JP (1) JP2023517035A (https=)
KR (1) KR20220150919A (https=)
CN (1) CN115361958A (https=)
AU (1) AU2021232614A1 (https=)
BR (1) BR112022017557A2 (https=)
CA (1) CA3170255A1 (https=)
WO (1) WO2021176001A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
SG11202004680UA (en) 2017-11-22 2020-06-29 Mesoblast Int Sarl Cellular compositions and methods of treatment i
EP4181935A1 (en) * 2020-07-20 2023-05-24 Brainstorm Cell Therapeutics Ltd. Methods and compositions for treating lung conditions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101626772A (zh) * 2007-03-22 2010-01-13 奥西里斯治疗公司 间充质干细胞及其用途
US20160199413A1 (en) * 2013-08-01 2016-07-14 Isletone Ab Mscs in the treatment of inflammatory pulmonary diseases
CN105796598A (zh) * 2014-12-29 2016-07-27 西比曼生物科技（上海）有限公司 一种用于治疗慢性阻塞性肺疾病的脂肪间充质祖细胞复合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6251295B1 (en) 1998-01-08 2001-06-26 Nexell Therapeutics Inc. Method for recirculation washing of blood cells
EP3461884B1 (en) * 2004-03-22 2025-05-28 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
US20120087868A1 (en) * 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
US20200108099A1 (en) * 2017-02-15 2020-04-09 Rohto Pharmaceutical Co., Ltd. Therapeutic agent for pulmonary fibrosis, ptprr expression-promotor, and kit for treatment of pulmonary fibrosis
CL2017002357A1 (es) * 2017-09-16 2018-04-20 Cells For Cells S A Método de obtención de una composición que contiene una población específica de células mesenquimales de cordón umbilical y sus usos
CN111297899A (zh) * 2020-02-21 2020-06-19 云南雅盛医疗科技有限公司 一种脐带间充质干细胞在制备治疗新型冠状肺炎药物中的应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101626772A (zh) * 2007-03-22 2010-01-13 奥西里斯治疗公司 间充质干细胞及其用途
US20160199413A1 (en) * 2013-08-01 2016-07-14 Isletone Ab Mscs in the treatment of inflammatory pulmonary diseases
CN105796598A (zh) * 2014-12-29 2016-07-27 西比曼生物科技（上海）有限公司 一种用于治疗慢性阻塞性肺疾病的脂肪间充质祖细胞复合物

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DANIEL J. 等: "A Placebo-Controlled, Randomized Trial of Mesenchymal Stem Cells in COPD", CHEST, vol. 143, no. 6, 30 June 2013 (2013-06-30), pages 1590 *
GUOPING ZHENG等: "Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study", RESPIRATORY RESEARCH, vol. 15, 4 April 2014 (2014-04-04), pages 1 - 10 *
JIAJIA CHEN等: "Clinical Study of Mesenchymal Stem Cell Treatment for Acute Respiratory Distress Syndrome Induced by Epidemic Influenza A (H7N9) Infection: A Hint for COVID-19 Treatment", ENGINEERING, vol. 6, 28 February 2020 (2020-02-28), pages 4 *
PHUONG LE THI BICH等: "Allogeneic umbilical cord-derived mesenchymal stem cell transplantation for treating chronic obstructive pulmonary disease: a pilot clinical study", STEM CELL RESEARCH & THERAPY, vol. 11, 13 February 2020 (2020-02-13), pages 1 - 14 *
PHUONG THI-BICH LE等: "Umbilical cord derived stem cell (ModulatistTM) transplantation for severe chronic obstructive pulmonary disease: a report of two cases", BIOMED RES THER, vol. 3, no. 10, 29 October 2016 (2016-10-29), pages 902 - 909 *
顾问等: "间充质干细胞治疗呼吸系统疾病的研究进展", 中华肺部疾病杂志(电子版), no. 01, 20 February 2016 (2016-02-20), pages 90 - 94 *

Also Published As

Publication number Publication date
US20230293589A1 (en) 2023-09-21
AU2021232614A1 (en) 2022-09-29
WO2021176001A1 (en) 2021-09-10
BR112022017557A2 (pt) 2022-12-27
JP2023517035A (ja) 2023-04-21
EP4114418A1 (en) 2023-01-11
CA3170255A1 (en) 2021-09-10
KR20220150919A (ko) 2022-11-11

Similar Documents

Publication Publication Date Title
US20230165904A1 (en) Method for treating hyperinflammation using mesenchymal lineage precursor or stem cells
CN115361960A (zh) 用于治疗慢性移植物抗宿主病的方法
CN115361958A (zh) 使用间充质谱系前体或干细胞治疗炎症性肺病的方法
KR20220152240A (ko) 염증성 장 질환 ii의 치료 방법
US20230172991A1 (en) Method for treating inflammatory bowel disease i
US20240207323A1 (en) Method for treating acute respiratory distress syndrome (ards) using mesenchymal lineage precursor or stem cells
AU2021403025A1 (en) Method of treating progressive heart failure in subjects with class ii heart failure
WO2023119239A1 (en) Method of treating severe graft versus host disease
CN117337184A (zh) 使用间充质谱系前体细胞或干细胞治疗急性呼吸窘迫综合征(ards)的方法
AU2024332651A1 (en) Third line treatment for gvhd
KR20260061190A (ko) GvHD에 대한 3차 치료

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination