CN1153582C - Veterinary liniment containing azedarachin and its preparation - Google Patents
Veterinary liniment containing azedarachin and its preparation Download PDFInfo
- Publication number
- CN1153582C CN1153582C CNB011070633A CN01107063A CN1153582C CN 1153582 C CN1153582 C CN 1153582C CN B011070633 A CNB011070633 A CN B011070633A CN 01107063 A CN01107063 A CN 01107063A CN 1153582 C CN1153582 C CN 1153582C
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- China
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- toosendanin
- liniment
- veterinary
- cosolvent
- dispersant
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Abstract
The present invention relates to high efficiency, low toxicity and low residual plant external application liniment for preventing and treating the raising mammal ectoparasite-itch mites. The liniment is prepared by that an insection and mite killing activity ingredient which is contained in azedarachin is used, and extract is mixed with 0.1 to 50% of toosendanin, 2 to 40% of emulsifying agents, 1 to 20% of cosolvent, 1 to 20% of penetrating promoting agents and 1 to 20% of dispersing agents. The liniment can rapidly reach a mite body to perform a maximal mite killing effect so that the pathogenetic condition is rapidly improved. The liniment is suitable for different mammal gaile, and simultaneously, has a certain treating effect on other ectoparasite.
Description
Affiliated technical field:
The present invention relates to a kind of veterinary liniment that contains Toosendanin and preparation method thereof technology, promptly utilize active ingredient in the Fructus Toosendan to be mixed with and can effectively prevent and treat the mammal vermin---the phyteral externally-applied liniment of acaricide.
Background technology:
For a long time, the acaricide of the single use chemosynthesis of people is prevented and treated the mammal acaricide,, gamma hch fat as two first, demodicid mite are clean, phoxim and dichlorvos etc., acarid produces insect resistace, prevention effect worse and worse, and this lamp medicament causes the person poultry poisoning to person poultry toxicity Da Yi, life-time service, a large amount of residue problems that also can have pesticide are along with Developing of Animal Industry has the trend that increases year by year in causing harm of some regional acaricides.
Summary of the invention:
The objective of the invention is to propose a kind of veterinary liniment that contains Toosendanin, it can the timely and effective epizoic acarid of mammal of killing.
Another object of the present invention provides the production method that a kind of preparation contains the veterinary liniment of Toosendanin, and this method technology is simple, with short production cycle, with low cost.
Purpose of the present invention reaches by following technical measures:
With the Toosendanin in plant Fructus Toosendan skin or the seed is the insecticidal activity composition, and by pressing the preparation of column weight amount percentage ratio with emulsifying agent, cosolvent, short penetrating agent, dispersant, acquisition can prevent and treat the mammal phyteral liniment of acaricide on one's body
Toosendanin 0.1%～60%, emulsifying agent 2%～30%,
Cosolvent 1%～25% short penetrating agent 1%～25%,
Dispersant 1%～20%,
Mentioned emulsifier is many sorbitol esters, tween, alkyl sodium sulfate, sodium lauryl sulfate, alkyl benzene sulfonate; Cosolvent is acetone, isoamyl alcohol, phenol, ethyl acetate, dimethyl sulfoxide; Short penetrating agent is fatty sulfenic acids salt, laurocapram, maleic acid two short ester sodium sulfonates; Dispersant is naphthalene sulfonate, alkylsulfonate, polyethenoxy ether sulphonate, diisopropyl phosphate.
A kind of preparation method that contains the Toosendanin veterinary liniment as described is characterized in that:
Earlier Fructus Toosendan bark or chinaberry seed are fully ground, concentrate evaporate to dryness with the petroleum ether reflux, extract, and obtain ligroin extraction, reuse 95% ethanol refluxes to extract and concentrates evaporate to dryness acquisition ethanol extraction, ligroin extraction and ethanol extraction are merged, promptly obtain the Toosendanin concentrate of insecticidal activity composition;
Successively add Toosendanin concentrate, emulsifying agent, cosolvent, short penetrating agent and dispersant in reactor in proportion successively, temperature in the kettle is controlled at 30～60 ℃, stirs promptly to make liniment.
What the invention provides a kind of efficient, low toxicity, low-residual raises mammal vermin---the phyteral externally-applied liniment of acaricide in order to control.It utilizes the pesticide and miticide actility composition that contains in the Fructus Toosendan, make liniment by combinations by a certain percentage such as extract and emulsifying agent, cosolvent, short penetrating agent, dispersants, can arrive the demodicid mite body rapidly, bring into play its maximum miticidal effect, the state of an illness is taken a turn for the better rapidly, this liniment is applicable to various mammal acaricides, simultaneously other vermins is also had certain double effect of controlling.
Embodiment: liniment consists of Fructus Toosendan extract 45% by weight percentage, emulsifying agent 25%, and cosolvent 10%, short penetrating agent 10%, dispersant 10% is formulated.Put on the skin behind 500,1000,2000 times of the liniment dilute with waters that makes and impose on pig body surface (1Kg/50Kg), put on the skin altogether four times in the 1st day, the 3rd day, the 7th day and the 8th day, preventive effect reaches 96.67%, 93.33% and 86.67% after January.
Claims (6)
1, a kind of veterinary liniment that contains Toosendanin, it is characterized in that: with the Toosendanin in plant Fructus Toosendan skin or the seed is the insecticidal activity composition, by pressing the preparation of column weight amount percentage ratio with emulsifying agent, cosolvent, short penetrating agent, dispersant, acquisition can prevent and treat the mammal phyteral liniment of acaricide on one's body
Toosendanin 0.1%～60%
Emulsifying agent 2%～30%
Cosolvent 1%～25%
Short penetrating agent 1%～25%
Dispersant 1%～20%.
2, a kind of veterinary liniment that contains Toosendanin according to claim 1 is characterized in that: emulsifying agent is many sorbitol esters, tween, alkyl sodium sulfate, sodium lauryl sulfate, alkyl benzene sulfonate.
3, a kind of veterinary liniment that contains Toosendanin according to claim 1 is characterized in that: cosolvent is acetone, isoamyl alcohol, phenol, ethyl acetate, dimethyl sulfoxide.
4, a kind of veterinary liniment that contains Toosendanin according to claim 1 is characterized in that: short penetrating agent is fatty sulfenic acids salt, laurocapram, maleic acid two short ester sodium sulfonates.
5, a kind of veterinary liniment that contains Toosendanin according to claim 1 is characterized in that: dispersant is naphthalene sulfonate, alkylsulfonate, polyethenoxy ether sulphonate, diisopropyl phosphate.
6, a kind of preparation method that contains the Toosendanin veterinary liniment according to claim 1 is characterized in that:
Earlier Fructus Toosendan bark or chinaberry seed are fully ground, concentrate evaporate to dryness with the petroleum ether reflux, extract, and obtain ligroin extraction, reuse 95% ethanol refluxes to extract and concentrates evaporate to dryness acquisition ethanol extraction, ligroin extraction and ethanol extraction are merged, promptly obtain the Toosendanin concentrate of insecticidal activity composition;
Successively add Toosendanin concentrate, emulsifying agent, cosolvent, short penetrating agent and dispersant in reactor in proportion successively, temperature in the kettle is controlled at 30～60 ℃, stirs promptly to make liniment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011070633A CN1153582C (en) | 2001-01-17 | 2001-01-17 | Veterinary liniment containing azedarachin and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011070633A CN1153582C (en) | 2001-01-17 | 2001-01-17 | Veterinary liniment containing azedarachin and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1318406A CN1318406A (en) | 2001-10-24 |
| CN1153582C true CN1153582C (en) | 2004-06-16 |
Family
ID=4656017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011070633A Expired - Fee Related CN1153582C (en) | 2001-01-17 | 2001-01-17 | Veterinary liniment containing azedarachin and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1153582C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083433B (en) * | 2014-07-21 | 2017-09-22 | 成都乾坤动物药业有限公司 | Treat animal psoroptic mange external application Chinese veterinary medicinal composition, using and preparation method thereof |
| CN109329077A (en) * | 2018-09-27 | 2019-02-15 | 江苏省协同医药生物工程有限责任公司 | A kind of anti parasitic experimental animal padding and preparation method thereof |
| CN109453179B (en) * | 2018-11-29 | 2020-11-27 | 广东省微生物研究所（广东省微生物分析检测中心） | Application of toosendanin in preparing medicine for preventing and treating fungal infection |
-
2001
- 2001-01-17 CN CNB011070633A patent/CN1153582C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1318406A (en) | 2001-10-24 |
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