CN115335377A - 吡啶并嘧啶酮类化合物 - Google Patents

吡啶并嘧啶酮类化合物 Download PDF

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Publication number
CN115335377A
CN115335377A CN202180023225.7A CN202180023225A CN115335377A CN 115335377 A CN115335377 A CN 115335377A CN 202180023225 A CN202180023225 A CN 202180023225A CN 115335377 A CN115335377 A CN 115335377A
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China
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compound
pharmaceutically acceptable
acceptable salt
mmol
och
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CN202180023225.7A
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CN115335377B (zh
Inventor
吴立方
孙飞
丁照中
陈曙辉
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Medshine Discovery Inc
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Medshine Discovery Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

一类吡啶并嘧啶酮类化合物，具体公开了式(IⅠ)所示化合物及其药学上可接受的盐。

Description

PCT国内申请，说明书已公开。

Claims (21)

  1. PCT国内申请，权利要求书已公开。
CN202180023225.7A 2020-03-23 2021-03-23 吡啶并嘧啶酮类化合物 Active CN115335377B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN202010208310 2020-03-23
CN2020102083108 2020-03-23
CN2020104825776 2020-05-29
CN202010482577 2020-05-29
CN202010761556 2020-07-31
CN2020107615568 2020-07-31
PCT/CN2021/082391 WO2021190502A1 (zh) 2020-03-23 2021-03-23 吡啶并嘧啶酮类化合物

Publications (2)

Publication Number Publication Date
CN115335377A true CN115335377A (zh) 2022-11-11
CN115335377B CN115335377B (zh) 2024-01-16

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CN202180023225.7A Active CN115335377B (zh) 2020-03-23 2021-03-23 吡啶并嘧啶酮类化合物

Country Status (2)

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CN (1) CN115335377B (zh)
WO (1) WO2021190502A1 (zh)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010045371A1 (en) * 2008-10-15 2010-04-22 Gilead Palo Alto, Inc. Pyrido- and pyrimido (1, 2-a) pyrimidine compounds useful as stearoyl coa desaturase inhibitors
WO2016177655A1 (en) * 2015-05-04 2016-11-10 F. Hoffmann-La Roche Ag Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
WO2018045150A1 (en) * 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
WO2018220253A1 (es) * 2017-06-01 2018-12-06 Oncostellae, S.L. Derivados de ácidos carboxílicos eficaces como inhibidores de la proteína quinasa

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010045371A1 (en) * 2008-10-15 2010-04-22 Gilead Palo Alto, Inc. Pyrido- and pyrimido (1, 2-a) pyrimidine compounds useful as stearoyl coa desaturase inhibitors
WO2016177655A1 (en) * 2015-05-04 2016-11-10 F. Hoffmann-La Roche Ag Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
WO2018045150A1 (en) * 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
WO2018220253A1 (es) * 2017-06-01 2018-12-06 Oncostellae, S.L. Derivados de ácidos carboxílicos eficaces como inhibidores de la proteína quinasa

Also Published As

Publication number Publication date
CN115335377B (zh) 2024-01-16
WO2021190502A1 (zh) 2021-09-30

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