CN115279360A - 局部用双氯芬酸组合物和方法 - Google Patents

局部用双氯芬酸组合物和方法 Download PDF

Info

Publication number
CN115279360A
CN115279360A CN202180019349.8A CN202180019349A CN115279360A CN 115279360 A CN115279360 A CN 115279360A CN 202180019349 A CN202180019349 A CN 202180019349A CN 115279360 A CN115279360 A CN 115279360A
Authority
CN
China
Prior art keywords
diclofenac
amount
joint
composition
topical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180019349.8A
Other languages
English (en)
Chinese (zh)
Inventor
D·N·R·卡拉拉
A·格尼尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring BV
Original Assignee
Ferring BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring BV filed Critical Ferring BV
Publication of CN115279360A publication Critical patent/CN115279360A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN202180019349.8A 2020-02-27 2021-02-25 局部用双氯芬酸组合物和方法 Pending CN115279360A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062982589P 2020-02-27 2020-02-27
US62/982,589 2020-02-27
PCT/NL2021/050125 WO2021172987A1 (en) 2020-02-27 2021-02-25 Topical diclofenac compositions and methods

Publications (1)

Publication Number Publication Date
CN115279360A true CN115279360A (zh) 2022-11-01

Family

ID=74858737

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180019349.8A Pending CN115279360A (zh) 2020-02-27 2021-02-25 局部用双氯芬酸组合物和方法

Country Status (9)

Country Link
US (1) US20230157979A1 (https=)
EP (1) EP4110320A1 (https=)
JP (1) JP2023515539A (https=)
CN (1) CN115279360A (https=)
AU (1) AU2021228521A1 (https=)
BR (1) BR112022016887A2 (https=)
CA (1) CA3169241A1 (https=)
MX (1) MX2022010593A (https=)
WO (1) WO2021172987A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120157536A1 (en) * 2010-12-20 2012-06-21 Polytherapeutics, Inc. Composition for transdermal administration of non-steroidal anti-flammatory drug
US20150064254A1 (en) * 2011-07-28 2015-03-05 Cadila Healthcare Limited Method for treatment of pain and inflammation
CN104428003A (zh) * 2012-07-12 2015-03-18 辉凌公司 双氯芬酸制剂
US20160166524A1 (en) * 2014-12-12 2016-06-16 Gavis Pharmaceuticals Topical pharmaceutical gel composition of diclofenac sodium

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE534373T1 (de) 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US20140113970A1 (en) * 2012-10-22 2014-04-24 Mallinckrodt LLC Covidien Dispensing system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120157536A1 (en) * 2010-12-20 2012-06-21 Polytherapeutics, Inc. Composition for transdermal administration of non-steroidal anti-flammatory drug
US20150064254A1 (en) * 2011-07-28 2015-03-05 Cadila Healthcare Limited Method for treatment of pain and inflammation
CN104428003A (zh) * 2012-07-12 2015-03-18 辉凌公司 双氯芬酸制剂
US20160166524A1 (en) * 2014-12-12 2016-06-16 Gavis Pharmaceuticals Topical pharmaceutical gel composition of diclofenac sodium

Also Published As

Publication number Publication date
CA3169241A1 (en) 2021-09-02
US20230157979A1 (en) 2023-05-25
BR112022016887A2 (pt) 2022-10-18
AU2021228521A1 (en) 2022-10-13
MX2022010593A (es) 2022-12-13
EP4110320A1 (en) 2023-01-04
WO2021172987A1 (en) 2021-09-02
JP2023515539A (ja) 2023-04-13

Similar Documents

Publication Publication Date Title
JP6434104B2 (ja) ジクロフェナク製剤
US8647665B2 (en) Methods of treating hot flashes with formulations for transdermal or transmucosal application
JP4610741B2 (ja) 無水状態の局所的皮膚調製剤
CN106604717A (zh) 局部用双氯芬酸钠组合物
US20180344640A1 (en) Econazole composition and methods of treatment therewith
US9468618B2 (en) Topical pharmaceutical gel composition of diclofenac sodium
CN113347975B (zh) 用于治疗侵蚀性手骨关节炎的孟鲁司特
JP4824954B2 (ja) 口内炎治療のための口腔用組成物
CN115279360A (zh) 局部用双氯芬酸组合物和方法
RU2830586C1 (ru) Композиции на основе диклофенака для местного применения и связанные с ними способы
CN121152629A (zh) 药物组合物
US9687549B2 (en) Topical pharmaceutical gel composition of diclofenac sodium
EP1242062B1 (en) Anhydrous gel comprising nsaid for topical administration to the oral cavity
EP4382104A1 (en) Dyclonine for use in the topical treatment of hand-foot syndrome
US20160263065A1 (en) Topical pharmaceutical gel composition of diclofenac sodium
MX2008013207A (es) Metodos para tratamiento de bochornos con formulaciones para aplicacion transdermica o transmucosa.
HK1050484B (en) Clonidine preparations

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination