CN115254449A

CN115254449A - Sample centrifugation mechanism and sample analyzer

Info

Publication number: CN115254449A
Application number: CN202210943603.XA
Authority: CN
Inventors: 曹胜; 覃伯奇
Original assignee: Zhongyuan Huiji Biotechnology Co Ltd
Current assignee: Zhongyuan Huiji Biotechnology Co Ltd
Priority date: 2022-08-08
Filing date: 2022-08-08
Publication date: 2022-11-01

Abstract

The invention discloses a sample centrifugal mechanism and a sample analyzer, wherein the sample centrifugal mechanism comprises a support, a tray, an in-out component, a centrifugal pressing component and the like, the support is provided with a first position and a second position, the tray component comprises a movable seat for supporting a disc and is in sliding connection with the support, the in-out bin component comprises an in-out driving component for driving the movable seat to move between the first position and the second position, the centrifugal pressing component arranged at the second position comprises a movable pressing head and a pressing seat which are in rotating connection, a pressing driving component, a fixed pressing head and a centrifugal driving component which are connected, the movable pressing head and the fixed pressing head are arranged correspondingly, at least one of the movable pressing head and the fixed pressing head is a magnetic sucking component and attracts each other, and the pressing seat is movably connected with the support. When the movable seat is located at the second position, the pressing driving part drives the pressing seat to drive the movable pressing head to be close to the fixed pressing head along the support and to press the disk, and the centrifugal driving part drives the fixed pressing head to enable the disk to rotate. The sample centrifugal mechanism of the invention can not generate larger vibration and noise.

Description

Sample centrifugation mechanism and sample analyzer

Technical Field

The invention relates to the technical field of medical equipment, in particular to a sample centrifugal mechanism and a sample analyzer.

Background

Currently, for the analysis of whole blood samples, it is usually necessary to put the whole blood sample into a disk and obtain plasma through centrifugation, and then put the plasma into a sample analyzer. However, before the centrifugal machine centrifuges the disk, the disk needs to be compressed, and if the disk cannot be compressed, the disk is easily deviated, so that the centrifugation of the sample in the disk is incomplete. The conventional centrifuge generally compresses the disk by increasing a contact area with the disk, but increases a centrifugal mass, so that the conventional centrifuge generates large vibration and noise when centrifuging a sample.

In view of the above-mentioned drawbacks, there is a need for a new sample centrifugation mechanism and sample analyzer.

Disclosure of Invention

The invention mainly aims to provide a sample centrifugation mechanism and a sample analyzer, and aims to solve the problems of large vibration, noise and the like generated when an existing centrifuge centrifuges a sample.

To achieve the above object, the present invention provides a sample centrifugation mechanism comprising:

the bracket is provided with a first position and a second position at intervals;

the tray assembly comprises a movable seat for supporting a disc, and the movable seat is connected with the bracket in a sliding manner;

the warehouse inlet and outlet assembly comprises an inlet and outlet driving piece, and the inlet and outlet driving piece is used for driving the movable seat to move between the first position and the second position;

the centrifugal pressing assembly is arranged at the second position and comprises a movable pressing head, a pressing seat, a pressing driving piece, a fixed pressing head and a centrifugal driving piece, the movable pressing head is rotatably connected with the pressing seat, the fixed pressing head is connected with the centrifugal driving piece, the movable pressing head is arranged corresponding to the fixed pressing head, at least one of the movable pressing head and the fixed pressing head is a magnetic suction piece and attracts each other, and the pressing seat is movably connected with the support;

when the movable seat is located at the second position, the pressing driving part is used for driving the pressing seat to move relative to the support so as to drive the movable pressure head to be close to the fixed pressure head and press the disc, and the centrifugal driving part is used for driving the fixed pressure head to enable the disc to rotate.

Preferably, the disc runs through and has seted up the through-hole, fixed pressure head with the equal butt of activity pressure head in through-hole department has the clearance between and, in order with the disc compresses tightly, the sliding seat is equipped with dodges the groove, be equipped with on the tray and dodge the hole, dodge the groove with it all is used for dodging to dodge the hole fixed pressure head.

Preferably, fixed pressure head includes the pressure head support and compresses tightly magnet, be equipped with the mounting hole on the pressure head support, compress tightly magnet inlay and adorn in the mounting hole, the activity pressure head be with compress tightly the magnetism pressure head that magnet attracted mutually, it is equipped with the mounting panel to compress tightly the seat, the activity pressure head is rotationally located on the mounting panel, just the activity pressure head with one side that fixed pressure head corresponds is equipped with the protruding axle, the protruding axle is used for inserting in the mounting hole, compress tightly magnet with the equal butt of protruding axle in through-hole department has the clearance between and, with will the disc compresses tightly, and works as when the disc compresses tightly, it still is used for the drive to compress tightly the driving piece it is relative to compress tightly the seat the support motion, so that the mounting panel with the activity pressure head has the clearance in upper and lower direction.

Preferably, the support is provided with a slide rail extending in the vertical direction, and the pressing seat is provided with a slide groove connected with the slide rail in a sliding manner.

Preferably, the compressing driving part is shared with the in-out driving part, an ascending elastic part is connected between the compressing seat and the support, when the movable seat is located at the second position, the movable seat is clamped with the compressing seat, the in-out driving part is further used for driving the movable seat to drive the compressing seat to move relative to the support so as to drive the movable pressure head to be close to the fixed pressure head and compress the disk, and the centrifugal driving part is used for driving the fixed pressure head to enable the disk to rotate.

Preferably, be equipped with on the support with sliding connection's of movable seat orbit deflector, business turn over storehouse subassembly still include respectively with the support with movable seat swing joint's fork, the business turn over driving piece is used for the drive the fork drives the movable seat is in the first position with move between the second position, work as the movable seat is located during the second position, the business turn over driving piece still is used for passing through the fork drive the movable seat drives it is relative to compress tightly the seat support motion, in order to drive the activity pressure head is close to fixed pressure head compresses tightly the disc.

Preferably, the orbit deflector has the orbit groove, be equipped with the guide way on the sliding seat and insert the tracking round pin of guide way, the tracking round pin still inserts the orbit groove and with the cell wall sliding connection in orbit groove, and with the fork is kept away from the one end swing joint of support, the business turn over driving piece is used for the drive the fork is followed the motion of orbit groove, it is equipped with the separation and reunion draw-in groove on the seat to compress tightly, works as the sliding seat is located during the second position, the tracking round pin card goes into the separation and reunion draw-in groove.

Preferably, the track groove includes a horizontal track groove and a vertical track groove which are mutually communicated, the in-out driving member is configured to drive the swing fork to drive the movable seat to move between the first position and the second position along the horizontal track groove, and the in-out driving member is configured to drive the swing fork to drive the movable pressure head to approach the fixed pressure head through the pressing seat along the vertical track groove so as to press the disk.

Preferably, round hole and waist type hole have been seted up respectively to the both ends of pendulum fork, the tracking round pin inserts the round hole, be equipped with the fixed pin on the support, the business turn over driving piece is equipped with the power round pin, the fixed pin with the power round pin all inserts in the waist type hole.

In addition, the invention also provides a sample analyzer, which comprises a shell and the sample centrifugal mechanism contained in the shell.

The sample centrifugal mechanism comprises a support, a tray assembly, a bin inlet and outlet assembly and a centrifugal pressing assembly, wherein the support is provided with a first position and a second position at intervals, the tray assembly comprises a movable seat for supporting a disc, the movable seat is connected with the support in a sliding manner, the bin inlet and outlet assembly comprises an inlet and outlet driving piece, the inlet and outlet driving piece is used for driving the movable seat to move between the first position and the second position, the centrifugal pressing assembly is arranged at the second position and comprises a movable pressing head, a pressing seat, a pressing driving piece, a fixed pressing head and a centrifugal driving piece, the movable pressing head is rotatably connected with the pressing seat, the fixed pressing head is connected with the centrifugal driving piece, the movable pressing head is arranged corresponding to the fixed pressing head, at least one of the movable pressing head and the fixed pressing head is a magnetic suction piece and attracts each other, and the pressing seat is movably connected with the support. When a sample in a disc needs to be centrifugally moved, the in-and-out driving piece drives the movable seat to reach the first position, the disc bearing the sample is placed on the movable seat, the in-and-out driving piece drives the movable seat to move from the first position to the second position, the pressing driving piece drives the pressing seat to move relative to the support after the movable seat is at the second position, so that the movable pressing head is driven to be close to the fixed pressing head and to press the disc, the centrifugal driving piece drives the fixed pressing head to enable the disc to rotate after the disc is pressed, the pressing driving piece drives the pressing seat to move relative to the support after centrifugation is finished, so that the movable pressing head is driven to be far away from the fixed pressing head and to loosen the disc, and the in-and-out driving piece drives the movable seat to move from the second position to the first position. According to the invention, at least one of the movable pressure head and the fixed pressure head for pressing the disk is set as the magnetic part, and the movable pressure head and the fixed pressure head are mutually attracted, so that the disk can be pressed when centrifuging, rather than increasing the contact area of the movable pressure head and the fixed pressure head with the disk, the mass of the fixed pressure head and the movable pressure head which do centrifugal motion along with the disk is small, the integral centrifugal mass is reduced, and the sample centrifugal mechanism can not generate larger vibration, noise and the like when centrifuging a sample on the disk.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.

Fig. 1 is a schematic view illustrating a perspective structure of a movable seat in a first position according to an embodiment of the present invention;

fig. 2 is a schematic view of another perspective structure of the movable seat at the first position according to an embodiment of the present invention;

fig. 3 is a schematic view of another perspective structure of the movable seat in the first position according to an embodiment of the present invention;

FIG. 4 is a schematic cross-sectional view illustrating the movable seat in the first position according to an embodiment of the present invention;

FIG. 5 is an exploded view of the movable base at the first position according to an embodiment of the present invention;

FIG. 6 is a schematic structural diagram illustrating a view angle of the movable seat at the second position and the disk at the released state according to an embodiment of the present invention;

FIG. 7 is a structural diagram of another view angle of the movable seat at the second position and the disk at the unclamped state according to an embodiment of the present invention;

FIG. 8 is a structural diagram of another view angle of the movable seat at the second position and the disk in the released state according to an embodiment of the present invention;

FIG. 9 is a schematic cross-sectional view illustrating the movable seat in the second position and the disk in the unclamped state according to an embodiment of the present invention;

FIG. 10 is a schematic structural diagram illustrating a view angle of the movable seat at the second position and the disk being in a compressed state according to an embodiment of the present invention;

FIG. 11 is a structural diagram of another view angle of the movable seat at the second position and the disk being in the compressed state according to an embodiment of the present invention;

FIG. 12 is a schematic structural diagram illustrating a view angle of the movable seat at the second position and the disk being in a compressed state according to an embodiment of the present invention;

fig. 13 is a schematic cross-sectional view illustrating the movable base at the second position and the disk being in a compressed state according to an embodiment of the present invention.

The reference numbers illustrate:

reference numerals	Name (R)	Reference numerals	Name (R)
				1	Support frame	2221	Clamping part
11	First position	223	Retaining wall
				12	Second position	2231	Accommodating space
13	Fixing pin	3	Warehouse in and out component
				14	Second connecting piece	31	In-out driving piece
15	Sliding rail	311	Power pin
				16	Track guide plate	32	Swinging fork
161	Track groove	33	Transmission member
				1611	Horizontal track groove	331	Screw mandrel
1612	Vertical track groove	332	Screw rod nut seat
				2	Tray assembly	4	Centrifugal pressing assembly
21	Movable seat	41	Movable pressure head
				211	Tracking pin	42	Compressing seat
212	Guide seat	421	Pull-down clamping groove
				213	First connecting piece	422	Sliding chute
2131	First sub-guide rail	423	Clutch clamping groove
				2132	Second sub-guide rail	43	Fixed pressure head
214	Guide groove	44	Centrifugal driving piece
				22	Tray	45	Uplink elastic member
221	Jacking elastic piece	10	Disc sheet
				222	Pull rod

The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that all directional indicators (such as up, down, left, right, front, back \8230;) in the embodiments of the present invention are only used to explain the relative positional relationship between the components, the motion situation, etc. in a specific posture (as shown in the attached drawings), and if the specific posture is changed, the directional indicator is changed accordingly.

In addition, descriptions such as "first", "second", etc. in the present invention are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless explicitly specified otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "connected," "secured," and the like are to be construed broadly, and for example, "secured" may be a fixed connection, a removable connection, or an integral part; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be interconnected within two elements or in a relationship where two elements interact with each other unless otherwise specifically limited. The specific meanings of the above terms in the present invention can be understood according to specific situations by those of ordinary skill in the art.

In addition, the technical solutions in the embodiments of the present invention may be combined with each other, but it must be based on the realization of the technical solutions by those skilled in the art, and when the technical solutions are contradictory to each other or cannot be realized, such a combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.

The invention provides a sample centrifugation mechanism and a sample analyzer, and aims to solve the problems that the existing centrifuge can generate larger vibration, noise and the like when a sample is centrifuged.

Referring to fig. 1 to 5, the sample centrifugation mechanism includes a support 1, a tray assembly 2, a warehouse entry assembly 3 and a centrifugation pressing assembly 4, the support 1 is provided with a first position 11 and a second position 12 at an interval, the tray assembly 2 includes a movable seat 21 for supporting a disk 10, the movable seat 21 is slidably connected to the support 1, the warehouse entry assembly 3 includes an entry and exit driving member 31, the entry and exit driving member 31 is used for driving the movable seat 21 to move between the first position 11 and the second position 12, the centrifugation pressing assembly 4 is provided at the second position 12 and includes a movable pressure head 41, a pressing seat 42, a pressing driving member, a fixed pressure head 43 and a centrifugation driving member 44, the movable pressure head 41 is rotatably connected to the pressing seat 42, the fixed pressure head 43 is connected to the centrifugation driving member 44, the movable pressure head 41 is disposed corresponding to the fixed pressure head 43, at least one of the movable pressure head 41 and the fixed pressure head 43 is a magnetic attraction member and attracts each other, and the pressing seat 42 is movably connected to the support 1. When the movable seat 21 is located at the second position 12, the pressing driving member is used to drive the pressing seat 42 to move relative to the frame 1 to bring the movable pressing head 41 close to the fixed pressing head 43 and press the disk 10, and the centrifugal driving member 44 is used to drive the fixed pressing head 43 to rotate the disk 10.

The sample centrifugal mechanism comprises a support 1, a tray assembly 2, a warehouse entry assembly 3 and a centrifugal pressing assembly 4, wherein the support 1 is provided with a first position 11 and a second position 12 at intervals, the tray assembly 2 comprises a movable seat 21 for supporting a disk 10, the movable seat 21 is in sliding connection with the support 1, the warehouse entry assembly 3 comprises an entry and exit driving piece 31, the entry and exit driving piece 31 is used for driving the movable seat 21 to move between the first position 11 and the second position 12, the centrifugal pressing assembly 4 is arranged at the second position 12 and comprises a movable pressing head 41, a pressing seat 42, a pressing driving piece, a fixed pressing head 43 and a centrifugal driving piece 44, the movable pressing head 41 is in rotating connection with the pressing seat 42, the fixed pressing head 43 is connected with the centrifugal driving piece 44, the movable pressing head 41 is arranged corresponding to the fixed pressing head 43, at least one of the movable pressing head 41 and the fixed pressing head 43 is a magnetic suction piece and attracts each other, and the pressing seat 42 is movably connected with the support 1. When the movable seat 21 is located at the second position 12, the pressing driving member is configured to drive the pressing seat 42 to move relative to the frame 1 to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the disk 10, and the centrifugal driving member 44 is configured to drive the fixed pressing head 43 to rotate the disk 10. When a centrifugal motion of a sample in the disk 10 is required, the in-and-out driving member 31 drives the movable seat 21 to reach the first position 11, the disk 10 containing the sample is placed on the movable seat 21, the in-and-out driving member 31 drives the movable seat 21 to move from the first position 11 to the second position 12, after the movable seat 21 is at the second position 12, the pressing driving member drives the pressing seat 42 to move relative to the bracket 1, so as to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the disk 10, the pressing seat 42 moves upward a small distance to be separated from the movable pressing head 41, and then the disk 10 is centrifuged again, so that the disk 10 is continuously clamped by magnetic force between the fixed pressing head 43 and the movable pressing head 41, the disk 10 and the fixed pressing head 43 rotate together centrifugally, the centrifugal driving member 44 drives the fixed pressing head 43 to rotate the disk 10, when the centrifugation is finished, the pressing driving member drives the pressing seat 42 to move relative to the bracket 1, so as to drive the movable pressing head 41 to move away from the fixed pressing head 43 and release the disk 10, and the in-and-out driving member 31 drives the movable seat 21 to move from the second position 12 to the first position 11. In the invention, at least one of the movable pressure head 41 and the fixed pressure head 43 for pressing the disk 10 is set as a magnetic element, and the movable pressure head 41 and the fixed pressure head 43 are mutually attracted, so that the disk 10 can be pressed when centrifuging, rather than increasing the contact area between the movable pressure head 41 and the fixed pressure head 43 and the disk 10, the mass of the fixed pressure head 43 and the movable pressure head 41 which move along with the centrifugal motion of the disk 10 is small, thereby reducing the integral centrifugal mass, and preventing the sample centrifuging mechanism from generating larger vibration, noise and the like when centrifuging a sample on the disk 10.

As shown in fig. 2 and 7, a feeding and discharging in-situ optical coupler blocking piece is arranged on the movable seat 21, a feeding and discharging in-situ optical coupler is arranged on the support 1, the feeding and discharging in-situ optical coupler blocking piece can horizontally move in and out along with the tray assembly 2, the feeding and discharging in-situ optical coupler blocking piece is matched with the feeding and discharging in-situ optical coupler and used for determining the horizontal in-situ position of the movable seat 21 and the disk 10, and the position is located right above the centrifugal motor.

Please refer to fig. 6 and 10, a pressing in-situ optical coupler blocking piece is arranged on the pressing seat 42, a pressing assembly in-situ optical coupler is arranged on the bracket 1, and when the pressing assembly goes upward to the original position, the pressing in-situ optical coupler blocking piece blocks the pressing assembly in-situ optical coupler.

A circumferential in-situ optical coupling groove is formed in the disk 10, a circumferential in-situ optical coupler of the disk 10 is arranged on the support 1, and the circumferential in-situ optical coupler groove and the circumferential in-situ optical coupler of the disk 10 jointly act to determine the circumferential position of the disk 10, so that the trouble that the disk 10 needs to be manually positioned or manually clamped and locked in the circumferential direction when a reaction disk is put in can be avoided; the groove can be a hollow near fan-shaped hole or a fan-shaped light-transmitting hole on the opaque film. The in-situ optical coupling at the periphery of the disk 10 can be a reflection type, a transmission type, a Hall element and the like. When the transmission-type optical coupler is used, the transmitting end and the receiving end surface of the optical coupler are respectively positioned on the upper surface and the lower surface of the disk 10, and a light-transmitting or light-proof hole is formed in the disk 10 corresponding to the optical path region of the optical coupler; in addition, the disk 10 and the circumferential reflection type in-situ optical coupler can be changed into a U-shaped groove-shaped opposite-emission type optical coupler, the emitting and receiving end surfaces of the optical coupler are positioned outside the upper surface and the lower surface of the disk 10, and a light-transmitting or light-proof hole is formed in the disk 10 corresponding to the optical path region of the optical coupler.

It should be noted that the centrifugal disk 10 of the present invention includes a cavity, a pressing positioning hole, a sample loading and sucking hole, and a circumferential in-situ hole, and can contain a whole blood sample, and separate a plasma sample to be measured after centrifugation, and the centrifugal disk 10 is provided with an inner circle hole and an outer circle hole, the inner circle hole is a hole for adding the whole blood sample into the centrifugal disk, and the outer circle hole is a hole for sucking the centrifuged plasma sample out of the disk 10.

In one embodiment, a through hole is formed through the disc 10, the fixed pressing head 43 abuts against the movable pressing head 41 at the through hole with a gap therebetween to compress the disc 10, the movable seat 21 is provided with an avoiding groove, and the tray 22 is provided with an avoiding hole, wherein the avoiding groove and the avoiding hole are both used for avoiding the fixed pressing head 43. In order to make the disk 10 stable and reliable during the centrifugal movement, a through hole is formed through the disk 10, and the fixed pressure head 43 abuts against the movable pressure head 41 at the through hole to press the disk 10 tightly. Moreover, movable seat 21 is equipped with the groove of dodging, is equipped with the hole of dodging on the tray 22, when movable seat 21 got into second position 12 by first position 11, dodges the groove and can dodge fixed pressure head 43, when tray 22 pulls down, fixed pressure head 43 can be dodged to the hole of dodging on the tray 22 to can guarantee that fixed pressure head 43 can insert the through-hole. It should be noted that the lower surface of the movable pressing head 41 never contacts the upper surface member of the fixed pressing head 43, so that the movable pressing head 41 and the fixed pressing head 43 maintain a gap, and the movable pressing head 41 can press the disk 10 against the fixed pressing head 43.

Further, fixed pressure head 43 includes pressure head support 1 and compresses tightly magnet, be equipped with the mounting hole on pressure head support 1, it inlays and adorns in the mounting hole to compress tightly magnet, activity pressure head 41 is the magnetic pressure head that attracts mutually with compressing tightly magnet, it is equipped with the mounting panel to compress tightly seat 42, activity pressure head 41 rotationally locates on the mounting panel, and one side that activity pressure head 41 and fixed pressure head 43 correspond is equipped with the protruding axle, the protruding axle is used for inserting in the mounting hole, it has the clearance just between to compress tightly magnet and protruding axle butt in through-hole department, in order to compress tightly disk 10, and when disk 10 compresses tightly, it still is used for the drive to compress tightly seat 42 relative support 1 motion to compress tightly the driving piece, so that mounting panel and activity pressure head 41 have the clearance in upper and lower direction. When the fixed pressure head 43 and the movable pressure head 41 approach each other, the fixed pressure head 43 and the movable pressure head 41 generate a suction force in the vertical axial direction to press the disk 10 to be centrifuged together. The longitudinal section of the movable pressure head 41 is h-shaped, the h-shaped groove width of the movable pressure head 41 is slightly larger than the thickness of the mounting plate of the movable pressure head 41 mounted on the pressing seat 42, after the disk 10 is pressed, the mounting plate slightly moves upwards, the movable pressure head 41 is separated from the mounting plate and rotates at high speed with the disk 10 during centrifugation, and the projecting shaft of the movable pressure head 41 is slightly smaller than the mounting hole. Wherein, the mounting plate restricts the micro-motion of the movable pressure head 41 relative to the movable pressure head in the horizontal plane and the up-and-down direction; a pressing magnet for providing an attractive force required for pressing the disk 10 when the disk 10 is centrifuged; the indenter holder 1 provides axial and circumferential positioning for the disc 10 when the disc 10 is centrifuged, and also provides a mounting for the compression magnet. It should be noted that the height of the magnet of the fixed ram 43 is smaller than the depth of the mounting hole, and the magnet can be protected from being pressed and bumped.

Furthermore, a slide rail 15 extending in the vertical direction is provided on the bracket 1, and a sliding groove 422 slidably connected to the slide rail 15 is provided on the pressing base 42. In an embodiment, the pressing base 42 is provided with a front slider and a rear slider, both of which have a sliding groove 422, the front slider is arranged on the front side of the pressing base 42, the rear slider is arranged on the rear side of the pressing base 42, the support 1 is provided with a front sliding rail 15 and a rear sliding rail 15, the front slider is in sliding connection with the front sliding rail 15, the rear slider is in sliding connection with the rear sliding rail 15, so that the pressing base 42 can stably and reliably slide along the support 1 in the vertical direction.

Further, the compressing driving member is shared by the in-out driving member 31, an upward elastic member 45 is connected between the compressing seat 42 and the support 1, when the movable seat 21 is located at the second position 12, the movable seat 21 is clamped with the compressing seat 42, the in-out driving member 31 is further configured to drive the movable seat 21 to drive the compressing seat 42 to move relative to the support 1, so as to drive the movable pressure head 41 to approach the fixed pressure head 43 and compress the disk 10, and the centrifugal driving member 44 is configured to drive the fixed pressure head 43 to rotate the disk 10. In an embodiment, the support 1 is provided with a track guide plate 16, the support 1 is provided with a first position 11 and a second position 12 at intervals, the tray assembly 2 comprises a movable seat 21, the movable seat 21 is respectively connected with the track guide plate 16 and the support 1 in a sliding manner, the warehouse entry and exit assembly 3 comprises an entry and exit driving part 31, the centrifugal pressing assembly 4 is arranged at the second position 12 and comprises a movable pressing head 41 and a pressing seat 42 which are connected in a rotating manner, and a fixed pressing head 43 and a centrifugal driving part 44 which are connected, the movable pressing head 41 and the fixed pressing head 43 are arranged correspondingly, and the pressing seat 42 is movably connected with the support 1 and an uplink elastic part 45 is connected between the movable pressing head and the fixed pressing head 43. As shown in fig. 1 to 4, when a sample in the disc 10 needs to be centrifugally moved, the in-out driving element 31 drives the movable seat 21 to reach the first position 11, the disc 10 with the sample is placed on the movable seat 21, the in-out driving element 31 drives the movable seat 21 to move from the first position 11 to the second position 12, as shown in fig. 6 to 9 and 13, at this time, the movable seat 21 is engaged with the pressing seat 42 at the second position 12, the in-out driving element 31 drives the movable seat 21 to move along the track guide plate 16 again, and drives the movable pressing head 41 on the pressing seat 42 to approach the fixed pressing head 43 to press the disc 10, as shown in fig. 10 to 13, at this time, the ascending elastic element 45 is deformed, and after the disc 10 is pressed, the centrifugal driving element 44 drives the fixed pressing head 43 to rotate the disc 10, when the centrifugation is finished, the in-out driving element 31 drives the track guide plate 16 on the movable seat 21 to move from the second position 12 to the first position 11, it is noted that the movable seat 21 is separated from the pressing head 42, and the movable seat 42 is reset to drive the pressing head 42 to move along the first position 11, and the movable seat 21 to move further to move along the first position, and the pressing head 41 is released. The centrifugal pressing component 4 is arranged at the second position 12 and can not move along with the tray component 2 at the first position 11 and the second position 12, and the centrifugal driving component 44 is fixedly arranged at the second position 12, so that the sample centrifugal mechanism can not generate larger vibration, noise and the like when centrifuging a sample on the disc 10; and the warehouse inlet and outlet component 3 realizes warehouse inlet and outlet of the tray component 2, so that the left and right size of the whole machine of the sample centrifugal mechanism is greatly reduced relative to other instruments, the space is saved, and the weight is reduced.

In an embodiment, the track guide plate 16 slidably connected to the movable seat 21 is disposed on the support 1, the in-out assembly 3 further includes a swing fork 32 movably connected to the support 1 and the movable seat 21, the in-out driving member 31 is configured to drive the swing fork 32 to drive the movable seat 21 to move between the first position 11 and the second position 12, and when the movable seat 21 is located at the second position 12, the in-out driving member 31 is further configured to drive the movable seat 21 to drive the pressing seat 42 to move relative to the support 1 through the swing fork 32, so as to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the disk 10. Referring to fig. 4, when the disc 10 needs to be placed on the movable seat 21, the in-out driving member 31 drives the swing fork 32 to drive the movable seat 21 to move from the second position 12 to the first position 11, at this time, the swing fork 32 is located at the first position, and when the disc 10 is ejected out of the compartment, the swing fork 32 swings to the outermost position outside the compartment; referring to fig. 9, when the movable seat 21 needs to move from the first position 11 to the second position 12, the in-out driving element 31 drives the swing fork 32 to drive the movable seat 21 to move from the first position 11 to the second position 12, at this time, the swing fork 32 is located at the second position, the disk 10 retracts into the compartment but is not compressed, and the movable seat 21 and the compressing seat 42 are in a disengaged state; referring to fig. 13, when the disc 10 needs to be compressed, the in-out driving element 31 continues to drive the swing fork 32 and drive the movable seat 21 to move, so that the movable seat 21 is clamped with the compressing seat 42, the in-out driving element 31 continues to drive the swing fork 32 and drive the movable seat 21 to move, and drives the movable pressure head 41 to approach the fixed pressure head 43 through the compressing seat 42 to compress the disc 10, at this time, the swing fork 32 is located at the third position, and the disc 10 is compressed by the compressing assembly at the second position 12. The in-out bin assembly 3 utilizes the pendulum fork 32 to enlarge the stroke, and realizes the in-out bin movement of the disk 10.

Further, as shown in fig. 6, 9 and 13, the track guide plate 16 has a track groove 161, the movable seat 21 is provided with a guide groove 214 and a track pin 211 inserted into the guide groove 214, the track pin 211 is further inserted into the track groove 161 and slidably connected with a groove wall of the track groove 161, and is movably connected with one end of the swing fork 32 away from the bracket 1, the in-and-out driving member 31 is used for driving the swing fork 32 to move along the track groove 161, the pressing seat 42 is provided with a clutch slot 423, and when the movable seat 21 is located at the second position 12, the track pin 211 is clamped into the clutch slot 423. The track groove 161 restricts the movement of the tracking pin 211, the guide groove 214 is opened along the vertical direction to restrict the tracking pin 211 from moving up and down, the tracking pin 211 can realize the horizontal in-and-out movement and the up-and-down pressing and separating movement of the disk 10, the tracking pin 211 is coaxially and rotatably connected with the hole at the upper end of the swing fork 32, and meanwhile, the tracking pin can move up and down along the guide groove 214 and can move along the restricted track of the track groove 161. When the disk 10 retracts into the compartment, the tracking pin 211 is horizontally and rearwardly inserted into the clamping groove 423 of the clamping assembly, so as to drive the clamping assembly to move up and down. Furthermore, the clutch engaging groove 423 is a U-shaped notch facing horizontally outwards, so that when the disk 10 retracts into the compartment, the protruding end of the tracking pin 211 horizontally enters the groove, and the two cannot move vertically.

In addition, as shown in fig. 5, in an embodiment, the track slot 161 includes a horizontal track slot 1611 and a vertical track slot 1612 that are communicated with each other, the in-and-out driving element 31 is configured to drive the swing fork 32 to move along the horizontal track slot 1611 to drive the movable seat 21 to move between the first position 11 and the second position 12, and the in-and-out driving element 31 is configured to drive the swing fork 32 to drive the movable ram 41 to approach the fixed ram 43 through the pressing seat 42 along the vertical track slot 1612 to press the disk 10. When the swing fork 32 swings, the tracking pin 211 moves along the descending part of the track groove 161, thereby driving the pressing member to move up and down, and realizing the pressing and releasing of the disk 10.

As shown in fig. 3, two ends of the swing fork 32 are respectively provided with a circular hole and a waist-shaped hole, the tracking pin 211 is inserted into the circular hole, the fixing pin 13 is disposed on the bracket 1, the in-out driving member 31 is provided with a power pin 311, and both the fixing pin 13 and the power pin 311 are inserted into the waist-shaped hole. The fixed pin 13 is fixed on the bracket 1, the in-out driving piece 31 drives the pendulum fork 32 through the power pin 311, the pendulum fork 32 swings around the fixed pin 13 and drives the movable seat 21 to move through the tracking pin 211, so that the movable seat 21 can move between the first position 11 and the second position 12. The fixed pin 13 and the power pin 311 are inserted into the waist-shaped hole, so that the swing fork 32 can enlarge the stroke of the movable seat 21. It should be noted that the position of the power pin 311 may be arranged according to the actual situation, and the power pin 311 may be located between the tracking pin 211 and the fixing pin 13, or below the tracking pin 211 and the fixing pin 13.

Further, please refer to fig. 4, fig. 9 and fig. 13, in order to realize multiple functions, the tray assembly 2 further includes a tray 22 disposed on the movable seat 21, a jacking elastic member 221 is connected between the tray 22 and the movable seat 21, the disk 10 is disposed on the tray 22, a pull rod 222 having a clamping portion 2221 is disposed on the tray 22, a pull-down clamping slot 421 for clamping with the pull rod 222 is disposed on the pressing seat 42, when the movable seat 21 is located at the second position 12, the clamping portion 2221 is clamped with the pull-down clamping slot 421, and when the disk 10 is pressed, the in-out driving member 31 is further configured to drive the movable seat 21 to drive the pressing seat 42 to move relative to the support 1 through the swing fork 32, so as to drive the tray 22 to move relative to the movable seat 21 and separate the tray 22 from the disk 10. When the disk 10 retracts into the compartment, the pull-down clamp groove 421 is clamped with the T-shaped convex disk at the bottom of the pull rod 222 of the tray 22, so that the tray 22 can be driven by the pressing base 42 to move up and down, and when the pressing base 42 moves down, the tray 22 can be pulled down, so that the jacking elastic piece 221 is stressed to deform; after the movable seat 21 leaves the second position 12, the pull rod 222 is separated from the pull-down slot 421, and the lifting elastic member 221 is restored to its original state when not being acted by an external force, so that the tray 22 is lifted up until the tray 22 is pulled down next time, and the lifting elastic member 221 is stressed again to deform. The tray 22 carrying the disk 10 can enter and exit the bin along the guide rail and move up and down along the axial direction of the pull rod 222 at the same time, so that the centrifugal disk can complete the actions of entering and exiting the bin, pressing up and down and separating; the pressing assembly pulls the tray 22 downward to perform a pressing and releasing action of the disk 10 with respect to the fixed ram 43, and simultaneously drives the movable ram 41 to press the disk 10 from the upper surface of the disk 10. Moreover, since the tray 22 is pulled down and separated from the disk 10, the disk 10 is in a suspended state, so that the centrifugal quality is greatly reduced, the centrifugal obstruction is greatly reduced, the centrifugal speed is increased, the centrifugal time is shortened, and the problem that the emergency sample cannot be inserted for centrifugation during the working period of the centrifuge can be solved.

In the above embodiment, the movable base 21 is provided with the guide base 212, the guide base 212 is provided with the guide hole, the pull rod 222 is inserted into the guide hole, the elastic lifting element 221 is a spring, the elastic lifting element 221 is sleeved on the outer periphery of the pull rod 222, and the guide hole is used for receiving the elastic lifting element 221. In order to protect the jacking elastic members 221 and to make the jacking direction of the tray 22 more accurate, a guide seat 212 may be provided on the movable seat 21. The guide seat 212 has a guide hole vertically formed, the pull rod 222 is inserted into the guide hole, the jacking elastic member 221 is sleeved on the periphery of the pull rod 222, a guide space for accommodating the jacking elastic member 221 is formed between the guide hole and the pull rod 222, and the jacking elastic member 221 can be accommodated in the guide space when in a compression state, so that the jacking elastic member 221 is protected, and when the jacking elastic member 221 is restored, the jacking elastic member can also move along the guide space, which is beneficial to the stability of the tray 22 during jacking. In order to stably pull down and jack up the tray 22, the number of the pull rods 222 is 3, 3 pull rods 222 are arranged in a regular triangle shape, and the number of the jack-up elastic members 221 and the guide bases 212 is consistent with the number of the pull rods 222 and is uniformly and correspondingly arranged.

Wherein, the outer edge of the tray 22 is protruded upward to form a blocking wall 223, and the blocking wall 223 and the bottom wall of the tray 22 enclose an accommodating space 2231 for accommodating the disk 10. In order to prevent the disk 10 from sliding out of the tray 22 when the disk 10 is loaded into or unloaded from the magazine, a blocking wall 223 may be provided around the bottom wall of the tray 22, a storage space 2231 for storing the disk 10 is defined between the blocking wall 223 and the bottom wall of the tray 22, and the blocking wall 223 may limit the disk 10 in the horizontal direction.

Further, in order to realize multiple functions, the bottom of the movable seat 21 is provided with a first connecting piece 213, the bracket 1 is provided with a second connecting piece 14, and the first connecting piece 213 is movably connected with the second connecting piece 14. In an embodiment, the movable seat 21 is slidably connected to the support 1, in order to ensure that the movable seat 21 can accurately reach the first position 11 and the second position 12, the first connecting members 213 are disposed at two opposite ends of the bottom of the movable seat 21, the support 1 is provided with the second connecting members 14, and the second connecting members 14 are slidably connected to the first connecting members 213 in the same number and in a one-to-one correspondence. The connection between the first connector 213 and the second connector 14 can be a rolling connection, a sliding rail and slider fit connection, a conveyor belt connection, a sliding rod and connector, etc.

In the above embodiment, the first connector 213 includes the first sub-rail 2131 and the second sub-rail 2132 slidably connected to each other, the first sub-rail 2131 is connected to the movable base 21, and the second sub-rail 2132 is slidably connected to the second connector 14. When the second position 12 is far away from the first position 11, the first connection element 213 or the second connection element 14 may be configured as a multi-stage telescopic rail, in an embodiment, the first connection element 213 includes a first sub-rail 2131 and a second sub-rail 2132 that are slidably connected to each other, where the first sub-rail 2131 is connected to the movable base 21, the second sub-rail 2132 is slidably connected to the second connection element 14, when the movable base 21 moves from the second position 12 to the first position 11, the second sub-rail 2132 slides outwards relative to the second connection element 14, the first sub-rail 2131 slides outwards relative to the second sub-rail 2132, and the movable base 21 retracts to perform the opposite action. The multistage telescopic guide rail guides the disk 10 to enter and exit the bin, and the total length of the stroke of the multistage telescopic guide rail is larger than that of the guide rail during retraction.

Further, the first position 11 is an out-of-bin position, and the second position 12 is an in-bin position. In this embodiment, the in-out driving member 31 can drive the tray assembly 2 to move between the out-of-compartment position and the in-compartment position, so that the disk 10 placed on the tray assembly 2 can reach the in-compartment position, and the centrifugal pressing assembly 4 performs centrifugal pressing on the disk 10 at the in-compartment position, so that the disk 10 does not need to be centrifuged outside the machine.

Further, a transmission member 33 is connected between the in-out driving member 31 and the swing fork 32, in an embodiment, the transmission member 33 includes a lead screw 331 and a lead screw nut seat 332 disposed on the lead screw 331, a driving shaft of the in-out driving member 31 is connected with the lead screw 331, a power pin 311 is disposed on the lead screw nut seat 332, and a motor of the in-out lead screw 331 pushes the lead screw nut seat 332 to move back and forth, so that the swing fork 32 can be driven to swing by the power pin 311 on the lead screw nut seat 332, thereby realizing the in-out of the tray assembly 2. In another embodiment, the transmission member 33 comprises two racks spaced from each other and a gear disposed between the two racks and engaged with the two racks, wherein the rack located at the upper portion is disposed on the tray assembly 2, the rack located at the lower portion is disposed on the bracket 1, and the driving shaft of the in-out driving member 31 is coaxially connected with the gear. The gear is driven by the motor to rotate, so that the motor and the gear move along the horizontal direction, and the rack above the rack is driven to move relative to the rack on the support 1, so that the stroke of the tray component 2 relative to the support 1 can be amplified by one time, and the bin inlet and outlet of the tray component 2 can be realized.

In addition, the invention also provides a sample analyzer, which comprises a shell and the sample centrifugal mechanism contained in the shell. The specific structure of the sample centrifugal mechanism in the sample analyzer refers to the above embodiments, and since the sample analyzer adopts all the technical solutions of all the above embodiments, at least all the beneficial effects brought by the technical solutions of the above embodiments are achieved, and no further description is given here.

The sample analyzer can save the operation that a user needs to centrifuge a whole blood sample, and avoid complex operation; the biological safety risk of opening the cover outside the machine can be avoided; the waiting and transferring time from the centrifugal machine to the instrument can be shortened, and the result output speed of the emergency sample is improved; the vibration and noise of the centrifuge can be avoided; the cost and the occupied area of a centrifugal machine can be saved; compared with the existing centrifugal disk centrifugal assembly, the design of the centrifugal pressing assembly 4 can avoid the repeated meshing gear transmission and other precise transmission between the centrifugal disk and the centrifugal motor, thereby reducing the manufacturing difficulty and cost of the sample centrifugal mechanism.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims

1. A sample centrifugation mechanism, comprising:

the warehouse entry and exit assembly comprises an entry and exit driving piece, and the entry and exit driving piece is used for driving the movable seat to move between the first position and the second position;

the centrifugal pressing assembly is arranged at the second position and comprises a movable pressing head, a pressing seat, a pressing driving piece, a fixed pressing head and a centrifugal driving piece, the movable pressing head is rotationally connected with the pressing seat, the fixed pressing head is connected with the centrifugal driving piece, the movable pressing head is arranged corresponding to the fixed pressing head, at least one of the movable pressing head and the fixed pressing head is a magnetic suction piece and attracts each other, and the pressing seat is movably connected with the support;

2. The sample centrifugation mechanism of claim 1, wherein a through hole is formed through the disk, the fixed ram and the movable ram both abut against the through hole and have a gap therebetween to compress the disk, the movable seat is provided with an avoidance groove, the tray is provided with an avoidance hole, and the avoidance groove and the avoidance hole are both used for avoiding the fixed ram.

3. The sample centrifugation mechanism of claim 2, wherein the fixed ram comprises a ram support and a pressing magnet, the ram support is provided with a mounting hole, the pressing magnet is embedded in the mounting hole, the movable ram is a magnetic ram attracted to the pressing magnet, the pressing base is provided with a mounting plate, the movable ram is rotatably arranged on the mounting plate, one side of the movable ram corresponding to the fixed ram is provided with a protruding shaft, the protruding shaft is inserted into the mounting hole, the pressing magnet and the protruding shaft are both abutted against the through hole and have a gap therebetween so as to press the disk, and when the disk is pressed, the pressing driving member is further used for driving the pressing base to move relative to the support so that the mounting plate and the movable ram have a gap in the up-down direction.

4. The sample centrifugation mechanism of claim 1, wherein the support is provided with a slide rail extending in a vertical direction, and the compression block is provided with a chute slidably connected to the slide rail.

5. The sample centrifugation mechanism of any one of claims 1 to 4, wherein the compression drive member is shared with the in-out drive member, an upward elastic member is connected between the compression seat and the support, the movable seat is engaged with the compression seat when the movable seat is in the second position, the in-out drive member is further configured to drive the movable seat to drive the compression seat to move relative to the support so as to drive the movable ram to approach the stationary ram and compress the disk, and the centrifugation drive member is configured to drive the stationary ram to rotate the disk.

6. The specimen centrifugation mechanism of claim 5, wherein said frame defines a track guide plate slidably coupled to said movable mount, said in-out assembly further comprises a yoke movably coupled to said frame and said movable mount, respectively, said in-out actuator is configured to actuate said yoke to move said movable mount between said first position and said second position, and said in-out actuator is further configured to actuate said movable mount to move said clamping block relative to said frame via said yoke when said movable mount is in said second position, to move said movable clamp closer to said stationary clamp and clamp said disk.

7. The sample centrifugation mechanism of claim 6, wherein the track guide plate comprises a track slot, the movable seat comprises a guide slot and a tracking pin inserted into the guide slot, the tracking pin is further inserted into the track slot and slidably connected to a wall of the track slot, and is movably connected to an end of the fork away from the rack, the in-and-out driving member is configured to drive the fork to move along the track slot, the pressing seat comprises a clutch slot, and the tracking pin is engaged with the clutch slot when the movable seat is in the second position.

8. The sample centrifugation mechanism of claim 7, wherein the track slot comprises a horizontal track slot and a vertical track slot in communication with each other, the in-out actuator is configured to drive the fork along the horizontal track slot to move the movable stage between the first position and the second position, and the in-out actuator is configured to drive the fork along the vertical track slot to drive the movable ram via the clamping stage to move the movable ram adjacent to the fixed ram to clamp the disk.

9. The sample centrifugation mechanism of claim 7, wherein the fork has a circular hole and a kidney-shaped hole at each end, the tracking pin is inserted into the circular hole, the holder has a fixed pin, the in-out driving member has a power pin, and the fixed pin and the power pin are inserted into the kidney-shaped hole.

10. A sample analyzer, comprising a housing and the sample centrifugation mechanism of any one of claims 1-9 housed within the housing.