CN115251376A - Lutein ester nano microcapsule and preparation method thereof - Google Patents

Lutein ester nano microcapsule and preparation method thereof Download PDF

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CN115251376A
CN115251376A CN202210899535.1A CN202210899535A CN115251376A CN 115251376 A CN115251376 A CN 115251376A CN 202210899535 A CN202210899535 A CN 202210899535A CN 115251376 A CN115251376 A CN 115251376A
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lutein ester
water
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ester
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彭健
孟像海
胡晓珂
王鹏
闵军
方素云
张海坤
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Qingdao Kangxiaolu Biotechnology Co ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/10—Foods or foodstuffs containing additives; Preparation or treatment thereof containing emulsifiers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3544—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a lutein ester nanometer microcapsule which is characterized by comprising the following raw materials in parts by weight: 1-2 parts of lutein ester, 12-18 parts of wall material, 0.02-0.05 part of emulsifier, 0.3-0.5 part of water-based antioxidant and 120-150 parts of deionized water. And (4) portions are obtained. Also discloses a preparation method of the lutein ester nano microcapsule, and a final product is obtained by two times of embedding and low-temperature spray drying. The whole production process does not use any organic solvent, and the method has the advantages of low processing cost, simple and convenient operation and environmental protection.

Description

Lutein ester nano microcapsule and preparation method thereof
Technical Field
The invention relates to the technical field of deep processing of bioactive substances, in particular to a lutein ester nano microcapsule and a preparation method thereof.
Background
Lutein ester is an important carotenoid fatty acid ester, dark reddish brown fine particle. Most of the lutein esters existing in nature can be divided into trans-lutein esters and cis-lutein esters, and basically all trans-molecular configuration is the main. All-trans lutein esters can be further classified as: mono-and di-esters of lutein. It is widely existed in plant bodies such as marigold flower, pumpkin, cabbage, first vinasse, etc. Wherein, the content of marigold flowers is the most abundant, and is as high as 30 percent to 40 percent. At normal temperature, the high-purity lutein ester (with the content of 60% -95%) is golden yellow to orange red powder, is easily soluble in chlorohydrocarbons such as chloroform, dichloromethane and carbon dichloride, is soluble in solvents such as normal hexane, acetone, ethyl acetate and ethanol, has stronger stability than the lutein ester, and has larger damage to the lutein ester only under the factors of high temperature, strong acid, iron ion and oxygen. At present, the lutein ester is dissolved in an organic solvent by basically utilizing the characteristic of relatively high solubility in the organic solvent, and then the lutein ester is mixed with a wall material for shearing, emulsifying and spray drying to prepare the lutein ester. These methods require two phases of water and oil, use a large amount of raw materials, and are inconvenient to operate.
Disclosure of Invention
The lutein ester nano microcapsule comprises the following raw materials in parts by weight: 1-2 parts of lutein ester, 12-18 parts of wall materials, 0.02-0.05 part of emulsifier, 0.3-0.5 part of aqueous antioxidant and 120-150 parts of deionized water.
The lutein ester nano microcapsule comprises the following raw materials in parts by weight: 2 parts of lutein ester, 12 parts of wall material, 0.035 part of emulsifier, 0.5 part of aqueous antioxidant and 130 parts of deionized water.
The wall material is maltodextrin, the emulsifier is sucrose fatty acid ester, and the aqueous antioxidant is ascorbic acid or sodium ascorbate.
The preparation method of the lutein ester nano microcapsule is characterized by comprising the following steps:
step 1, adding lutein ester into a part of ionized water while stirring, keeping the lutein ester continuously stirred, starting a colloid mill to carry out ultrafine grinding on the lutein ester dispersed in the water, and sieving to obtain a feed liquid I;
step 2, pumping the first feed liquid into a high-pressure homogenizer for homogenization to obtain a second feed liquid;
step 3, dividing the rest deionized water into two parts, adding an emulsifier, a part of wall materials and a water-soluble antioxidant into one part, and performing shearing emulsification to obtain a material liquid III;
step 4, mixing the material liquid III and the material liquid II, and shearing and emulsifying again to obtain material liquid IV; then, feeding the feed liquid IV into a high-pressure homogenizer for homogenization to obtain feed liquid V;
step 5, adding the rest wall materials into the rest deionized water, mixing with the material liquid V after high-speed emulsification and dispersion, then shearing and emulsifying again, and then pumping into a high-pressure homogenizer for homogenization again to obtain an emulsion;
and 6, carrying out spray drying on the emulsion.
And in the steps 1 to 4, the temperature of the material is controlled not to exceed 40 ℃.
And in the step 2, homogenizing for 5-6 times under the homogenizing pressure of 120 Mpa.
The conditions of the emulsification and dispersion of the step are 3000 revolutions and the dispersion lasts for 3 to 7 minutes.
And (3) homogenizing for at least 3 times under the homogenization conditions of 120Mpa in the step (4) and the step (5).
The temperature of the spray drying is 50 ℃ to 80 ℃.
The invention has the following technical effects:
the method completely takes water as a medium, firstly adopts a high-speed colloid mill to crush the aqueous dispersion of the lutein ester to be below 40 mu m, then adopts a technical means of ultrahigh pressure homogenization to reduce the particle size of the lutein ester to be below 200nm, and then carries out two times of embedding, and improves the stability and the storage resistance of a finished product through two times of embedding; the wall material is dissolved firstly during the secondary embedding, so that the abnormal aggregation of the particles formed by the primary embedding during the addition of the wall material is avoided. The whole production process does not use any organic solvent, so that the processing cost is low, the operation is simple and convenient, and the environment is protected; the method does not need oil phase participation and high temperature to dissolve the lutein ester, has simple used raw materials, and avoids the inconvenience of operation caused by water and oil phases in the prior art; the adoption of the water phase can lower the viscosity of the material liquid, is more favorable for homogenization, can reduce the particle size of the material to an ideal effect, and is convenient for controlling the temperature of the material.
Drawings
FIG. 1 shows the stability test at 25 ℃ in example II
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any inventive step, are intended to be within the scope of the present invention.
Example one
Firstly, 40 parts of deionized water is put into a batching tank, and 1 part of lutein ester is added while stirring; and keeping continuously stirring, starting a colloid mill to carry out ultrafine grinding on the lutein ester dispersed in water, repeatedly grinding the lutein ester for at least 3 times by using the colloid mill, and filtering by using a 300-mesh sieve after grinding to obtain feed liquid I. The colloid mill grinds the lutein ester into particles, which is beneficial to the dispersion of the lutein ester in water and is also beneficial to reducing the times of high-pressure homogenization.
Homogenizing the obtained material liquid in a high pressure homogenizer under 120Mpa for 5-6 times to obtain material liquid II.
Then 0.02 emulsifier sucrose fatty acid ester, 7 parts maltodextrin and 0.3 water-soluble antioxidant are put into 60 parts deionized water, and are subjected to shearing emulsification for 3 minutes at 3000 revolutions to obtain feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again, wherein shearing and emulsifying are carried out for 3 minutes at 3000 revolutions, so as to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
And then adding the remaining 6 parts of maltodextrin into 30 parts of deionized water while stirring, carrying out high-speed emulsification dispersion for 3 minutes at 3000 revolutions, mixing with the feed liquid V, carrying out shearing emulsification for 3 minutes at 3000 revolutions, and then pumping into a high-pressure homogenizer of 120MPa for homogenizing for at least 3 times to complete secondary embedding to obtain the emulsion.
The temperature of the materials is kept not to exceed 40 ℃ in the steps.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein esters and antioxidants is minimized.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
Example two
Firstly, 40 parts of deionized water is taken in a batching tank, 1 part of lutein ester is added while stirring, the stirring state is kept continuously, a colloid mill is started to carry out ultrafine grinding on the lutein ester dispersed in water, the colloid mill is used for repeatedly grinding the lutein ester for at least 3 times, and after the grinding is finished, a 300-mesh sieve is used for filtering to obtain a feed liquid I.
Homogenizing the obtained material liquid in a high pressure homogenizer under 120Mpa for 5-6 times to obtain material liquid II.
And then placing 0.035 part of emulsifier sucrose fatty acid ester, 8 parts of maltodextrin and 0.5 part of water-soluble antioxidant in 60 parts of deionized water, and carrying out shearing emulsification for 5 minutes at 3000 revolutions to obtain a feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again, wherein shearing and emulsifying are carried out for 5 minutes at 3000 revolutions, so as to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
And adding the rest 4 parts of maltodextrin into 30 parts of deionized water while stirring, mixing with the feed liquid five after high-speed emulsification and dispersion, shearing and emulsifying for 5 minutes at 3000 revolutions, and then pumping into a high-pressure homogenizer with the pressure of 120MPa for homogenizing for at least 3 times to finish secondary embedding to obtain the emulsion.
In the above steps, the temperature of the material is kept not to exceed 40 ℃.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein ester and antioxidant is reduced as much as possible.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
EXAMPLE III
Firstly, 40 parts of deionized water is put into a batching tank, 2 parts of lutein ester is added while stirring, the stirring state is kept continuously, a colloid mill is started to carry out ultrafine grinding on the lutein ester dispersed in the water, the colloid mill is used for repeatedly grinding the lutein ester for at least 3 times, and after the grinding is finished, a 300-mesh sieve is used for filtering to obtain a feed liquid I.
And (3) adding the obtained feed liquid into a high-pressure homogenizer for homogenization under the homogenization pressure of 120Mpa, and after 5-6 times of homogenization, finishing homogenization to obtain feed liquid II.
Then, 0.05 part of emulsifier sucrose fatty acid ester, 6 parts of maltodextrin and 0.4 part of water-soluble antioxidant are placed in 30 parts of deionized water, and shearing emulsification is carried out for 7 minutes at 3000 revolutions to obtain feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again, wherein shearing and emulsifying are carried out for 7 minutes at 3000 revolutions, so as to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
And adding the remaining 6 parts of maltodextrin into 80 parts of deionized water while stirring, mixing with the feed liquid five after high-speed emulsification and dispersion, shearing and emulsifying for 7 minutes at 3000 revolutions, and then pumping into a high-pressure homogenizer with the pressure of 120MPa for homogenizing for at least 3 times to finish secondary embedding to obtain the emulsion.
The temperature of the materials is kept not to exceed 40 ℃ in the steps.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein ester and antioxidant is reduced as much as possible.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
Example four
Firstly, 40 parts of deionized water is put into a batching tank, 2 parts of lutein ester is added while stirring, the stirring state is kept continuously, a colloid mill is started to carry out ultrafine grinding on the lutein ester dispersed in the water, the colloid mill is used for repeatedly grinding the lutein ester for at least 3 times, and after the grinding is finished, a 300-mesh sieve is used for filtering to obtain a feed liquid I.
Homogenizing the obtained material liquid in a high pressure homogenizer under 120Mpa for 5-6 times to obtain material liquid II.
And then placing 0.05 part of emulsifier sucrose fatty acid ester, 12 parts of maltodextrin and 0.5 part of water-soluble antioxidant into 75 parts of deionized water, and carrying out 3000-turn shearing emulsification for 6 minutes to obtain a feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again, wherein shearing and emulsifying are carried out for 6 minutes at 3000 revolutions, so as to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
And then adding the remaining 6 parts of maltodextrin into 35 parts of deionized water while stirring, mixing with the feed liquid five after high-speed emulsification and dispersion, shearing and emulsifying for 6 minutes at 3000 revolutions, and then pumping into a high-pressure homogenizer with the pressure of 120Mpa for homogenizing for at least 3 times to complete secondary embedding to obtain the emulsion.
The temperature of the materials is kept not to exceed 40 ℃ in the steps.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein ester and antioxidant is reduced as much as possible.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
EXAMPLE five
Firstly, 40 parts of deionized water is put into a batching tank, 1 part of lutein ester is added while stirring, the stirring state is kept continuously, a colloid mill is started to carry out ultrafine grinding on the lutein ester dispersed in the water, the colloid mill is used for repeatedly grinding the lutein ester for at least 3 times, and after the grinding is finished, a 300-mesh sieve is used for filtering to obtain a feed liquid I.
Homogenizing the obtained material liquid in a high pressure homogenizer under 120Mpa for 5-6 times to obtain material liquid II.
Then 0.025 parts of emulsifier sucrose fatty acid ester, 10 parts of maltodextrin and 0.4 part of water-soluble antioxidant are put into 80 parts of deionized water, and shearing and emulsifying are carried out for 6 minutes at 3000 revolutions to obtain feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again for 6 minutes at 3000 revolutions to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
And adding the rest 4 parts of maltodextrin into 30 parts of deionized water while stirring, mixing with the feed liquid five after high-speed emulsification and dispersion, shearing and emulsifying for 6 minutes at 3000 revolutions, and then pumping into a high-pressure homogenizer with the pressure of 120MPa for homogenizing for at least 3 times to finish secondary embedding to obtain the emulsion.
The temperature of the materials is kept not to exceed 40 ℃ in the steps.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein ester and antioxidant is reduced as much as possible.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
Comparative example 1
Firstly, 30 parts of deionized water is put into a batching tank, 1 part of lutein ester is added while stirring, the stirring state is kept continuously, a colloid mill is started to carry out ultrafine grinding on the lutein ester dispersed in the water, the colloid mill is used for repeatedly grinding the lutein ester for at least 3 times, and after the grinding is finished, a 300-mesh sieve is used for filtering to obtain a feed liquid I.
Homogenizing the obtained material liquid in a high pressure homogenizer under 120Mpa for 5-6 times to obtain material liquid II.
And then 0.02 emulsifier sucrose fatty acid ester, 6 parts of maltodextrin and 0.3 water-soluble antioxidant are placed in 60 parts of deionized water, and are subjected to shearing emulsification for 3 minutes at 3000 revolutions to obtain a feed liquid III.
And mixing the material liquid III and the material liquid II, and shearing and emulsifying again, wherein shearing and emulsifying are carried out for 3 minutes at 3000 revolutions, so as to obtain material liquid IV. And then, pumping the material liquid IV into a high-pressure homogenizer for homogenization, wherein the homogenization pressure is 120Mpa, and homogenizing for at least 3 times to obtain material liquid V.
The temperature of the materials is kept not to exceed 40 ℃ in the steps.
And finally, carrying out low-temperature spray drying on the emulsion at the temperature of 50-80 ℃. The influence of temperature on lutein ester and antioxidant is reduced as much as possible.
The water-soluble antioxidant is ascorbic acid or isoascorbic acid.
Stability test the retention of lutein ester was measured by placing the powder products obtained in examples and comparative examples in an environment of a temperature of 25 ℃ and a humidity of 70% and in an environment of a temperature of 35 ℃ and a humidity of 70% for 6 months. The results are shown in the following table.
Figure BDA0003770468570000051
The finished lutein esters of the second and the comparative examples were placed at 25 ℃ and 70% humidity for 6 months, the retention rate was measured once per month, and a retention rate line graph of lutein esters was prepared according to the measured values, as shown in fig. 1. As can be seen from the attached figure 1, the technical scheme adopted by the invention has better lutein ester retention rate under the same conditions. The double-layer embedding can better isolate the influence of adverse factors such as temperature, metal ions, oxygen and the like on the lutein ester, and can improve the utilization rate of the lutein ester.

Claims (9)

1. The lutein ester nano microcapsule is characterized by comprising the following raw materials in parts by weight: 1-2 parts of lutein ester, 12-18 parts of wall material, 0.02-0.05 part of emulsifier, 0.3-0.5 part of water-based antioxidant and 120-150 parts of deionized water.
2. The lutein ester nanocapsule of claim 1, wherein the lutein ester nanocapsule comprises the following raw materials in parts by weight: 2 parts of lutein ester, 12 parts of wall material, 0.035 part of emulsifier, 0.5 part of aqueous antioxidant and 130 parts of deionized water.
3. The flavin ester nanocapsule according to claim 1 or 2, wherein: the wall material is maltodextrin, the emulsifier is sucrose fatty acid ester, and the aqueous antioxidant is ascorbic acid or sodium ascorbate.
4. A method for preparing the lutein ester nanocapsule according to any one of claims 1 to 3, comprising the following steps:
step 1, adding lutein ester into a part of ionized water while stirring, keeping the lutein ester continuously stirred, starting a colloid mill to carry out ultrafine grinding on the lutein ester dispersed in the water, and sieving to obtain a feed liquid I;
step 2, pumping the feed liquid I into a high-pressure homogenizer for homogenization to obtain feed liquid II;
step 3, dividing the rest deionized water into two parts, adding an emulsifier, a part of wall materials and a water-soluble antioxidant into one part, and performing shearing emulsification to obtain a material liquid III;
step 4, mixing the material liquid III and the material liquid II, and shearing and emulsifying again to obtain material liquid IV; then, feeding the feed liquid IV into a high-pressure homogenizer for homogenization to obtain feed liquid V;
step 5, adding the rest wall materials into the rest deionized water, mixing with the material liquid V after high-speed emulsification and dispersion, then shearing and emulsifying again, and then pumping into a high-pressure homogenizer for homogenization again to obtain an emulsion;
and 6, carrying out spray drying on the emulsion.
5. The method for preparing a flavoester nanocapsule according to claim 4, wherein: and in the steps 1 to 4, the temperature of the material is controlled not to exceed 40 ℃.
6. The method for preparing a flavoester nanocapsule according to claim 4, wherein: and in the step 2, homogenizing for 5-6 times under the homogenizing pressure of 120 Mpa.
7. The method of preparing a flavoester nanocapsule of claim 4, wherein the method comprises the steps of: the condition of the emulsification and dispersion in the step is 3000 revolutions, and the dispersion is carried out for 3-7 minutes.
8. The method for preparing a flavoester nanocapsule according to claim 4, wherein: and (4) homogenizing for at least 3 times under the homogenization conditions of 120Mpa in the step (4) and the step (5).
9. The method for preparing a flavoester nanocapsule according to claim 4, wherein: the temperature of the spray drying is 50 ℃ to 80 ℃.
CN202210899535.1A 2022-07-28 2022-07-28 Lutein ester nano microcapsule and preparation method thereof Pending CN115251376A (en)

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