CN115232018A - Production method of sodium glutamate (monosodium glutamate) continuous crystallization - Google Patents
Production method of sodium glutamate (monosodium glutamate) continuous crystallization Download PDFInfo
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- CN115232018A CN115232018A CN202210853626.1A CN202210853626A CN115232018A CN 115232018 A CN115232018 A CN 115232018A CN 202210853626 A CN202210853626 A CN 202210853626A CN 115232018 A CN115232018 A CN 115232018A
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- Prior art keywords
- glutamate
- sodium glutamate
- monosodium glutamate
- sodium
- effect
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- LPUQAYUQRXPFSQ-DFWYDOINSA-M monosodium L-glutamate Chemical compound [Na+].[O-]C(=O)[C@@H](N)CCC(O)=O LPUQAYUQRXPFSQ-DFWYDOINSA-M 0.000 title claims abstract description 76
- 235000013923 monosodium glutamate Nutrition 0.000 title claims abstract description 76
- 229940073490 sodium glutamate Drugs 0.000 title claims abstract description 41
- 238000002425 crystallisation Methods 0.000 title claims abstract description 37
- 239000004223 monosodium glutamate Substances 0.000 title claims abstract description 35
- 230000008025 crystallization Effects 0.000 title claims abstract description 23
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 claims abstract description 14
- 239000013078 crystal Substances 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 4
- 238000001704 evaporation Methods 0.000 claims description 8
- 238000007599 discharging Methods 0.000 claims description 6
- 239000012452 mother liquor Substances 0.000 claims description 5
- 239000002002 slurry Substances 0.000 claims description 5
- 230000008020 evaporation Effects 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000005086 pumping Methods 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229940024606 amino acid Drugs 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- -1 sodium amino acid Chemical class 0.000 claims 1
- 238000005265 energy consumption Methods 0.000 abstract description 3
- 238000011031 large-scale manufacturing process Methods 0.000 abstract description 2
- 238000004904 shortening Methods 0.000 abstract 1
- 238000007738 vacuum evaporation Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 10
- 239000007788 liquid Substances 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000000498 cooling water Substances 0.000 description 2
- 238000012840 feeding operation Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000019583 umami taste Nutrition 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 235000019631 acid taste sensations Nutrition 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019607 umami taste sensations Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/26—Multiple-effect evaporating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0018—Evaporation of components of the mixture to be separated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0018—Evaporation of components of the mixture to be separated
- B01D9/0022—Evaporation of components of the mixture to be separated by reducing pressure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention provides a monosodium glutamate crystallization method, which comprises the following steps: sequentially adding sodium glutamate (monosodium glutamate) solution into a multi-stage evaporator, and performing vacuum evaporation to enter a crystallizer; centrifuging and drying to obtain sodium glutamate (monosodium glutamate) crystals. The method has the advantages of reducing production cost, shortening crystallization period, reducing operation energy consumption, improving product quality, and good operation repeatability, can improve crystallization yield of sodium glutamate (monosodium glutamate), and is suitable for large-scale production of sodium glutamate (monosodium glutamate).
Description
Technical Field
The invention belongs to the technical field of sodium glutamate (monosodium glutamate) production, and particularly relates to a crystallization method of sodium glutamate (monosodium glutamate).
Background
Sodium glutamate (monosodium glutamate) molecular formula is C 5 H 8 NO 4 Na is a wide range of umami flavorings, is readily soluble in water, and its aqueous solution has a strong umami taste.
Monosodium glutamate also has effects of alleviating alkali, acid and bitter taste. Sodium glutamate participates in normal protein metabolism in human body, promotes oxidation process, and has health promotion effect on cranial nerve and liver.
The traditional production method is an intermittent crystallization operation mode, and specifically comprises the steps of conveying a decolored sodium glutamate solution to a crystallization tank, heating, concentrating under a negative pressure state, adding seed crystals to promote crystallization when the solution in the tank is close to a saturated solution, enabling the size and concentration of crystal grains in the crystallization tank to meet requirements after the operation for 8-10 hours, placing the crystallization tank at one time, and then cleaning the crystallization tank to prepare for crystallization of the next batch of material. The production method has the advantages of large quantity of equipment, high energy consumption, large occupied area, fussy operation of personnel, incapability of realizing automatic continuous operation and no contribution to industrial production.
In summary, there is an urgent need in the art to develop an efficient and stable continuous crystallization production method of sodium glutamate (monosodium glutamate), which can realize automatic and continuous operation of the device, reduce the personnel operation, reduce the energy consumption, and improve the production efficiency.
Disclosure of Invention
Therefore, the invention aims to provide a method for continuously crystallizing sodium glutamate (monosodium glutamate), which comprises the following steps;
1. conveying the sodium glutamate solution to a double-effect evaporator by a conveying pump, vacuumizing, evaporating and discharging;
2. conveying the sodium glutamate solution obtained by concentration in the step 1 to a one-effect crystallizer, vacuumizing, evaporating, growing crystals and discharging;
3. conveying the sodium glutamate solution obtained by crystallization in the step 2 to a crystallization assisting tank;
4. separating the crystal slurry in the crystallization assisting groove into sodium glutamate (monosodium glutamate) wet crystals and mother liquor by a centrifugal machine, and drying the sodium glutamate (monosodium glutamate) wet crystals to obtain sodium glutamate (monosodium glutamate);
in the crystallization method of sodium glutamate (monosodium glutamate), the concentration of the sodium glutamate solution in the step 1 is 42-45% (w/w), the evaporation temperature is 45-50 ℃, the vacuum degree is-0.085-0.09 MPa, and the feeding density is 1.100-1.120 kg/cm 3 The discharge density is 1.285-1.295 kg/cm 3 。
In the crystallization method of the sodium glutamate (monosodium glutamate), the evaporation temperature in the step 2 is 65-70 ℃, the vacuum degree is-0.065-0.07 MPa, the feeding density is 1.285-1.295 kg/cm < 3 >, and the discharging density is 1.385-1.395 kg/cm < 3 >) 3 。
In the crystallization method of sodium glutamate (monosodium glutamate), the granularity of the sodium glutamate (monosodium glutamate) finished product obtained after drying in the step 4 is 150-850 mu m.
From the above, the crystallization method of sodium glutamate (monosodium glutamate) of the present invention has at least the following advantages:
1) The continuous crystallization production method can realize one-time shutdown and cleaning in a continuous operation period of 25 days, and the traditional intermittent crystallization method has one-time shutdown and cleaning in a continuous operation period of 8-10 hours;
2) The continuous crystallization production method does not need seed crystal feeding operation in the running process, and the traditional intermittent crystallization method needs seed crystal feeding operation in each batch;
3) The continuous crystallization production method consumes 1.4 tons of steam per ton of sodium glutamate (monosodium glutamate) produced, and the traditional intermittent crystallization method consumes 2.7 tons of steam per ton of sodium glutamate (monosodium glutamate) produced;
4) The continuous crystallization production method uses 100 tons of circulating cooling water for producing one ton of sodium glutamate (monosodium glutamate), and the traditional intermittent crystallization method uses 260 tons of circulating cooling water for producing one ton of sodium glutamate (monosodium glutamate);
5) The range of the finished product sodium glutamate (monosodium glutamate) particles produced by the continuous crystallization production method is 150-850 mu m, and the range of the finished product sodium glutamate (monosodium glutamate) particles produced by the traditional intermittent crystallization method is 250-1700 mu m;
the method of the invention can stabilize and improve the crystallization yield of the sodium glutamate (monosodium glutamate), and the new crystallization method is suitable for the large-scale production of the sodium glutamate (monosodium glutamate).
Drawings
FIG. 1 is a schematic view showing the orientation of steam, vacuum and condensed water in an evaporator according to the crystallization method of the present invention.
FIG. 2 is a view showing the construction of a continuous crystallization evaporator according to the present invention.
Detailed Description
The technical solutions of the present invention are further described below by specific examples, and it should be understood that the following are only exemplary illustrations of the present invention, and are not intended to limit the scope of the claims of the present invention.
The embodiment of the invention provides a crystallization method of sodium glutamate (monosodium glutamate), which comprises the following steps:
the first step is as follows: starting a feed adjusting valve of the double-effect evaporator, feeding the double-effect evaporator, starting a circulating pump when the liquid level reaches 50%, then starting a feed pump of the first-effect crystallizer, feeding the first-effect crystallizer, setting the liquid level of the double-effect evaporator to be 50% and performing interlocking control with the feed adjusting valve of the double-effect evaporator;
the second step is that: opening a feeding adjusting valve of a first-effect crystallizer, feeding the first-effect crystallizer, starting a circulating pump when the liquid level reaches 50%, then starting a discharging pump of the first-effect crystallizer, pumping back flow to the first-effect crystallizer, setting the liquid level of a second-effect evaporator to be 50% and performing interlocking control with the feeding adjusting valve of the second-effect evaporator;
the third step: starting a vacuum pump, setting the pressure of a condenser to be-0.09 Mpa, simultaneously starting a steam automatic valve, and controlling the temperature of a heater of the single-effect crystallizer to be 85 ℃;
the fourth step: when the material density in the one-effect crystallizer reaches 1385kg/m < 3 >, a reflux pipeline of the one-effect crystallizer is washed, and after the washing is finished, the one-effect crystallizer discharges materials.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (8)
1. A production method of sodium glutamate (monosodium glutamate) continuous crystallization comprises the following steps:
1) Adding the sodium glutamate (monosodium glutamate) solution into a double-effect evaporator, vacuumizing, evaporating and discharging;
2) Adding the sodium amino acid (monosodium glutamate) solution obtained by concentration in the step 1) into a double-effect crystallizer, vacuumizing, evaporating, concentrating, crystallizing, and pumping the slurry to a crystal slurry tank;
3) And centrifugally separating the slurry in the slurry tank to obtain wet sodium glutamate crystals and mother liquor, and drying the wet sodium glutamate crystals to obtain the sodium glutamate crystals.
2. The method according to claim 1, wherein the concentration of the sodium glutamate (monosodium glutamate) solution in the step 1) is 42-45% (w/w), the evaporation temperature is 45-50 ℃, the vacuum degree is-0.085-0.09 MPa, and the feeding density is 1.100-1.120 kg/cm 3 The discharging density is 1.285-1.295 kg/cm 3 。
3. The method as claimed in claim 1, wherein the temperature of the evaporation in the step 2) is 65-70 ℃, the vacuum degree is-0.065-0.07 MPa, and the feeding density is 1.285-1.295 kg/cm 3 The discharge density is 1.385 to 1.395kg/cm 3 。
4. A process according to any one of claims 1 to 3, characterized in that it further comprises a step of continuing the concentration of the mother liquor obtained in step 3).
5. The method according to claim 4, wherein the step of concentrating the mother liquor is to mix the mother liquor with the raw material liquor according to a volume ratio of 2 to 3 to obtain the sodium glutamate (monosodium glutamate) solution in the step 1) of claim 1.
6. The process according to any one of claims 1 to 5, wherein the steam is passed in sequence from a single effect heater to a double effect heater.
7. The method according to any one of claims 1 to 5, wherein the vacuum in the method is arranged from the condenser to the two-effect separator and the one-effect crystallizer in sequence.
8. The method according to any one of claims 1 to 5, wherein the condensed water in the method is sent to a first-effect heater, a second-effect heater and a condenser in sequence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210853626.1A CN115232018A (en) | 2022-07-11 | 2022-07-11 | Production method of sodium glutamate (monosodium glutamate) continuous crystallization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210853626.1A CN115232018A (en) | 2022-07-11 | 2022-07-11 | Production method of sodium glutamate (monosodium glutamate) continuous crystallization |
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| Publication Number | Publication Date |
|---|---|
| CN115232018A true CN115232018A (en) | 2022-10-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210853626.1A Pending CN115232018A (en) | 2022-07-11 | 2022-07-11 | Production method of sodium glutamate (monosodium glutamate) continuous crystallization |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101120767A (en) * | 2007-07-30 | 2008-02-13 | 山东阜丰生物科技开发有限公司 | Multi-efficient evaporation technology for monosodium glutamate neutralization liquid |
| WO2008134937A1 (en) * | 2007-04-29 | 2008-11-13 | Changchun Dacheng Industrial Group Company Limited | A process for producing the ctystal of glutamic acid |
| CN102070475A (en) * | 2011-01-07 | 2011-05-25 | 山东阜丰生物科技开发有限公司 | Sodium glutamate double-action crystallization production process |
| CN102356862A (en) * | 2011-09-26 | 2012-02-22 | 肥城金塔机械有限公司 | Method and device for continuously preparing monosodium glutamate crystals |
| CN104027992A (en) * | 2014-03-07 | 2014-09-10 | 中盐安徽红四方股份有限公司 | A novel method of continuous evaporation to prepare sodium formate |
-
2022
- 2022-07-11 CN CN202210853626.1A patent/CN115232018A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008134937A1 (en) * | 2007-04-29 | 2008-11-13 | Changchun Dacheng Industrial Group Company Limited | A process for producing the ctystal of glutamic acid |
| CN101120767A (en) * | 2007-07-30 | 2008-02-13 | 山东阜丰生物科技开发有限公司 | Multi-efficient evaporation technology for monosodium glutamate neutralization liquid |
| CN102070475A (en) * | 2011-01-07 | 2011-05-25 | 山东阜丰生物科技开发有限公司 | Sodium glutamate double-action crystallization production process |
| CN102356862A (en) * | 2011-09-26 | 2012-02-22 | 肥城金塔机械有限公司 | Method and device for continuously preparing monosodium glutamate crystals |
| CN104027992A (en) * | 2014-03-07 | 2014-09-10 | 中盐安徽红四方股份有限公司 | A novel method of continuous evaporation to prepare sodium formate |
Non-Patent Citations (1)
| Title |
|---|
| 刘殿宇;: "三效蒸发器在谷氨酸二次母液上的应用", 发酵科技通讯, no. 02, pages 45 - 46 * |
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