CN115231013A - Antiserum preparation filling system with CIP, SIP function - Google Patents

Antiserum preparation filling system with CIP, SIP function Download PDF

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Publication number
CN115231013A
CN115231013A CN202210867382.2A CN202210867382A CN115231013A CN 115231013 A CN115231013 A CN 115231013A CN 202210867382 A CN202210867382 A CN 202210867382A CN 115231013 A CN115231013 A CN 115231013A
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CN
China
Prior art keywords
rod
cylinder
steam
cip
chassis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202210867382.2A
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Chinese (zh)
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CN115231013B (en
Inventor
姚晓东
钟玉玲
季冲
刘晓安
周军根
王建
刘奇
邓大义
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Jiangxi Biological Products Research Institute Co ltd
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Jiangxi Biological Products Research Institute Co ltd
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Publication date
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Priority to CN202210867382.2A priority Critical patent/CN115231013B/en
Publication of CN115231013A publication Critical patent/CN115231013A/en
Application granted granted Critical
Publication of CN115231013B publication Critical patent/CN115231013B/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003Filling medical containers such as ampoules, vials, syringes or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/42Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
    • B65B43/54Means for supporting containers or receptacles during the filling operation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02Sterilising, e.g. of complete packages
    • B65B55/04Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/06Sterilising wrappers or receptacles prior to, or during, packaging by heat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/24Cleaning of, or removing dust from, containers, wrappers, or packaging ; Preventing of fouling
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B65/00Details peculiar to packaging machines and not otherwise provided for; Arrangements of such details

Abstract

The invention discloses an antiserum preparation filling system with CIP and SIP functions, which relates to the technical field of filling equipment and comprises a base, wherein a box body is fixedly connected to the base, one end of the box body is detachably provided with a box cover, and the box cover is provided with a vacuum processor; the inside of the box body is rotatably provided with a fixed part for placing the bottle body; the fixed part is also provided with a sterilization assembly in a sliding way, the sterilization assembly comprises a ventilation shell, the ventilation shell is of a hollow structure, the inner wall of the ventilation shell is provided with air holes, the number of the air holes is equal to that of the fixed holes on the installation cylinder, the air holes are used for spraying steam, and the ventilation shell is also provided with air holes; the base is provided with a sealing component and a filling component, the filling component is used for infusing medicine, and the sealing component is used for sealing the bottle body; the invention has CIP and SIP functions, can realize online sterilization treatment of the bottle body, and can carry out filling and sealing operation of the bottle body in large batch.

Description

Antiserum preparation filling system with CIP, SIP function
Technical Field
The invention relates to the technical field of filling equipment, in particular to an antiserum preparation filling system with CIP and SIP functions.
Background
The ampoule bottle is a hard glass container which can be sealed by melting and is commonly used for storing medicines for injection, vaccines, serum and the like; is a transliteration of the latin amplla. Two types of neck, straight neck and curved neck are commonly used; the capacity is generally 1-25 ml; it is commonly used for liquid medicine for injection and also used for packaging oral liquid.
The current medical technology level is continuously improved, diseases are high-frequency phenomena in daily life of people, and hospitalization and medicine taking in the diseases are normal requirements; therefore, the production of the medicine is an important task, wherein the filling and sealing of the medicine are key links in the production of the medicine; the filling and sealing efficiency of the ampoule bottle determines the production efficiency and quality of the ampoule bottle medicine; the filling and sealing equipment of the prior ampoule bottle has single function, can not effectively sterilize the bottle body before filling, does not have CIP and SIP functions, and has relatively low efficiency.
The Chinese patent with the publication number of CN110540160B discloses a filling device suitable for ampoule bottles, which comprises a fixing table, wherein a feeding table is fixed at the left end of the fixing table, a feeding mechanism and a pressing mechanism are fixed on the feeding table, a guide frame is fixed on the feeding mechanism, a sliding seat is connected on the guide frame in a sliding manner, an adjustable injection head is arranged on the sliding seat and connected with a transfusion mechanism, the transfusion mechanism is fixed on the fixing table, a liquid return mechanism is fixed on the fixing table and connected with the transfusion mechanism, and the sliding seat is connected with the liquid return mechanism through a connecting rod set. This patent is applicable to the filling device of ampoule, helps improving degree of automation to improve work efficiency, but can not carry out a large amount of ampoule production, and the ampoule does not carry out sterilization process, can influence the medicine quality.
Disclosure of Invention
Aiming at the technical problems, the technical scheme provided by the invention can realize the sterilization treatment of the bottle bodies and can carry out the filling and sealing operation of the bottle bodies on a large scale.
The technical scheme adopted by the invention is as follows: an antiserum preparation filling system with CIP and SIP functions comprises a base, wherein a box body is fixedly connected to the base, a box cover is detachably arranged at one end of the box body, and a vacuum processor is arranged on the box cover; the fixing part comprises an installation cylinder, a plurality of fixing holes are formed in the circumference of the installation cylinder and used for placing the bottle body, and a clamping shell is sleeved on the outer circumference of the installation cylinder and used for fixing the bottleneck of the bottle body by rotating the clamping shell; the fixed part is also provided with a sterilization assembly in a sliding way, the sterilization assembly comprises a ventilation shell, the ventilation shell is of a hollow structure, the inner wall of the ventilation shell is provided with air holes, the number of the air holes is equal to that of the fixed holes on the mounting cylinder, the air holes are used for spraying steam, and the ventilation shell is also provided with air holes; the base is provided with a sealing component and a filling component, the filling component is used for infusing medicines, and the sealing component is used for sealing the bottle body.
Further, be provided with the steam chest on the box, the inboard sterilization subassembly intercommunication on fixed part of steam chest to carry out steam and carry, rotary mounting has the chassis on the base, and fixed part is fixed to be set up on the chassis, and fixed mounting has the motor that is used for driving the chassis on the base.
Furthermore, the fixed part comprises a fixed column fixedly connected with the chassis, and one end of the fixed column is fixedly connected with the mounting cylinder; the sterilization assembly comprises a lifting chassis in sliding connection with the fixed column and two screw rods rotating on the chassis, and the two screw rods and the lifting chassis form a screw pair; the lifting chassis is rotatably connected with the ventilation shell, the lifting chassis is rotatably provided with a rotating cylinder, and a push rod of the rotating cylinder is rotatably connected with the ventilation shell.
Furthermore, the sterilization assembly further comprises a steam swivel fixedly connected with the fixing column, the steam swivel is rotatably connected and communicated with the inner side of the steam box, the inner side of the steam swivel is communicated with a steam pipe, and one end of the steam pipe is communicated with the ventilation shell.
Furthermore, the filling part comprises a second mounting seat fixedly mounted on the base, a second sliding rod is slidably mounted on the second mounting seat, and a filling head is arranged at one end of the second sliding rod; and a second air cylinder is rotatably arranged on the second mounting seat, and a push rod of the second air cylinder is rotatably connected with the second sliding rod.
Furthermore, the sealing part comprises a first mounting seat fixedly mounted on the base, a first sliding rod is slidably mounted on the first mounting seat, a first air cylinder is rotatably mounted on the first mounting seat, and a push rod of the first air cylinder is rotatably connected with the first sliding rod; one end of the first sliding rod is connected with two clamping plates in a sliding manner, the two clamping plates are respectively provided with a kneading rod, one kneading rod is fixedly connected with the clamping plates, and the other kneading rod is connected with the clamping plates in a sliding manner; the two clamping plates are respectively and rotatably connected with a connecting rod, and a supporting rod is rotatably connected between the two connecting rods; the device comprises a sliding rod I, a control cylinder, a push rod, a support rod, a contact rod and a clamp plate, wherein the control cylinder is fixedly arranged at one end of the sliding rod I, the push rod of the control cylinder is fixedly connected with the push rod, the support rod is in sliding connection with the push rod of the control cylinder, a spring II used for providing elasticity is arranged between the push rod and the push rod of the control cylinder, the contact rod is fixedly arranged at one end of a rubbing rod which is arranged in a sliding mode with the clamp plate, and a spring I used for providing elasticity is arranged between the contact rod and the rubbing rod.
Further, a heating device is arranged between the two clamping plates.
Compared with the prior art, the invention has the beneficial effects that: (1) The bottle bodies in different directions can be filled by utilizing the rotation of the fixing part; (2) The invention has CIP and SIP functions, and can sterilize the bottle body by using the sterilization component; (3) The liquid in the bottle body can be removed by the rotating centrifugal force.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
Fig. 2 is a sectional view of the overall structure of the present invention.
Fig. 3 is a schematic structural view of the fixing member of the present invention.
FIG. 4 is an enlarged view of the invention shown at A in FIG. 3.
Fig. 5 is a partial schematic view of a fastening member of the present invention.
Fig. 6 is a schematic view of the structure of the sealing member and the filling member of the present invention.
FIG. 7 is an enlarged view of the invention shown at B in FIG. 6.
Reference numerals: 1-a base; 2-a sealing member; 3-a filling component; 4-a stationary part; 101-a box body; 102-a steam box; 103-box cover; 104-a vacuum processor; 105-a first motor; 106-a chassis; 201-cylinder one; 202-mounting seat one; 203-a first sliding rod; 204-clamping plate; 205-rubbing rod; 206-spring one; 207-contact bar; 208-a control cylinder; 209-connecting rod; 210-spring two; 211-struts; 212-a mandril; 301-mounting base two; 302-cylinder two; 303-a second sliding bar; 304-a filling head; 401-steam tube; 402-a vented housing; 403-lifting the chassis; 404-a screw mandrel; 405-a lead screw gear; 406-sun gear; 407-motor two; 408-a motor gear; 409-fixed columns; 410-steam swivel; 411-a rotary cylinder; 412-mounting the cartridge; 413-bottle body; 414-engaging the housing.
Detailed Description
The present invention will be further described with reference to specific examples, which are illustrative of the invention and are not to be construed as limiting the invention.
As shown in fig. 1, a box body 101 is fixedly arranged on a base 1, a steam box 102 is arranged on the box body 101, the steam box 102 can be externally connected with a steam pump, a box cover 103 is detachably arranged at one end of the box body 101, a vacuum processor 104 is arranged on the box cover 103, and the vacuum processor 104 is used for performing vacuum processing on the interior of the box body 101; the base 1 is provided with a sealing component 2 and a filling component 3.
As shown in fig. 2, fig. 3, fig. 4 and fig. 5, a first motor 105 is fixed on the base 1, a chassis 106 is rotatably mounted on the base 1, the first motor 105 is used for driving the chassis 106 to rotate, and the fixing part 4 is fixedly arranged on the chassis 106; the fixing component 4 comprises a fixing column 409 fixedly connected with the chassis 106, an installation cylinder 412 is fixedly connected to one end of the fixing column 409, a plurality of fixing holes are arranged on the circumference of the installation cylinder 412, the fixing holes are used for placing the bottle body 413, a clamping shell 414 is sleeved on the outer circumference of the installation cylinder 412, and the clamping shell 414 is rotated to fix the bottleneck of the bottle body 413.
The fixed part 4 is also provided with a sterilization assembly in a sliding manner, the sterilization assembly comprises a ventilation shell 402, the ventilation shell 402 is of a hollow structure, the inner wall of the ventilation shell 402 is provided with air holes, the number of the air holes is equal to that of the fixed holes on the mounting cylinder 412, the air holes are used for spraying steam, and the ventilation shell 402 is also provided with air holes; the sterilization assembly further comprises a lifting chassis 403 connected with the fixing column 409 in a sliding manner, and two screw rods 404 rotatably mounted on the chassis 106, wherein the two screw rods 404 and the lifting chassis 403 form a screw pair; one end of each of the two lead screws 404 is fixedly connected with a lead screw gear 405, a central gear 406 is rotatably mounted on the chassis 106, and the central gear 406 is meshed with the two lead screw gears 405; a second motor 407 is fixedly arranged on the chassis 106, a motor gear 408 is fixedly connected to an output shaft of the second motor 407, and the motor gear 408 is meshed with one central gear 406; the lifting chassis 403 is rotationally connected with the ventilation shell 402, a rotating cylinder 411 is rotationally mounted on the lifting chassis 403, and a push rod of the rotating cylinder 411 is rotationally connected with the ventilation shell 402; the sterilization assembly further comprises a steam swivel 410 fixedly connected with the fixing column 409, the steam swivel 410 is rotatably connected and communicated with the inner side of the steam box 102, the inner side of the steam swivel 410 is communicated with a steam pipe 401, and one end of the steam pipe 401 is communicated with the ventilation shell 402.
As shown in fig. 6 and 7, the filling component 3 includes a second mounting seat 301 fixedly mounted on the base 1, a second sliding rod 303 is slidably mounted on the second mounting seat 301, and a filling head 304 is arranged at one end of the second sliding rod 303; a second air cylinder 302 is rotatably mounted on the second mounting seat 301, and a push rod of the second air cylinder 302 is rotatably connected with a second sliding rod 303.
The sealing part 2 comprises a first mounting seat 202 fixedly mounted on the base 1, a first sliding rod 203 is slidably mounted on the first mounting seat 202, a first air cylinder 201 is rotatably mounted on the first mounting seat 202, and a push rod of the first air cylinder 201 is rotatably connected with the first sliding rod 203; one end of the first sliding rod 203 is connected with two clamping plates 204 in a sliding manner, the two clamping plates 204 are respectively provided with a kneading rod 205, one kneading rod 205 is fixedly connected with the clamping plate 204, and the other kneading rod 205 is connected with the clamping plate 204 in a sliding manner; the two clamping plates 204 are respectively and rotatably connected with a connecting rod 209, and a supporting rod 211 is rotatably connected between the two connecting rods 209; one end of the first sliding rod 203 is fixedly provided with a control cylinder 208, a push rod 212 is fixedly connected to a push rod of the control cylinder 208, a support rod 211 is slidably connected with the push rod of the control cylinder 208, a second spring 210 for providing elastic force is arranged between the push rod 212 and the push rod of the control cylinder 208, one end of a kneading rod 205 which is slidably arranged with the clamp plate 204 is fixedly provided with a contact rod 207, and a first spring 206 for providing elastic force is arranged between the contact rod 207 and the kneading rod 205.
The working principle of the invention is as follows: the invention has CIP and SIP functions and can realize online sterilization; firstly, the box cover 103 is detached from the box body 101, a plurality of bottle bodies 413 are positioned and placed through fixing holes in the mounting cylinder 412, and then the bottle necks of the bottle bodies 413 are clamped and fixed by rotating the clamping shell 414 on the outer side of the mounting cylinder 412; after the bottle 413 is fixedly installed, the two screw rods 404 rotate through the operation of the second motor 407 under the transmission of gears, so that the lifting chassis 403 and the ventilation shell 402 slide, the ventilation shell 402 moves to the height position of the installation cylinder 412, and the top of the ventilation shell 402 is attached to the top of the installation cylinder 412; the cover 103 is remounted on the housing 101 and operated by the vacuum processor 104 to vacuum-process the enclosed space formed by the housing 101 and the cover 103.
When the bottle 413 is sterilized, a steam pump is externally connected with the steam box 102, high-temperature steam is transmitted to the ventilating shell 402 through the steam pipe 401 and is released through an air hole in the inner wall of the ventilating shell 402, the air hole is aligned with the bottle opening of the bottle 413, and the steam is sprayed into the bottle 413 to perform sterilization; the steam at the jet can be released from a vent on the vented housing 402; when the steam is liquefied into water drops, the water drops need to be further removed; at this time, the rotating cylinder 411 controls the ventilating housing 402 to rotate by a preset angle, so that the ventilating hole is aligned with the mouth of the bottle body 413, the base plate 106 is driven to rotate by the motor one 105, so that the fixing part 4 rotates, and the centrifugal force generated by the rotation throws the water drops out of the interior of the bottle body 413.
As shown in the angle of fig. 1, when filling is performed, vent housing 402 moves and misaligns with mounting cylinder 412, leaving vial 413 exposed; the second air cylinder 302 controls the second sliding rod 303 to slide, so that the filling head 304 penetrates through the vent hole and enters the bottle 413 to fill the medicine; the rotation of the fixing part 4 is controlled by a first motor 105, so that the bottles 413 in different directions are filled with medicines; when packaging is carried out, the first air cylinder 201 controls the first sliding rod 203 to slide, so that the two clamping plates 204 are conveyed to two sides of the bottle opening of the bottle body 413, an operator can arrange a heating device between the two clamping plates 204 to release a preset temperature to soften the bottle opening of the bottle body 413, then the control air cylinder 208 controls the ejector rod 212 to move, under the elastic force action of the second spring 210, the support rod 211 moves, under the connecting action of the connecting rod 209, the two clamping plates 204 slide, so that the softened bottle opening is clamped by the two rubbing rods 205, the ejector rod 212 continues to move, when the ejector rod 212 contacts and extrudes the contact rod 207, the rubbing rod 205 connected with the contact rod 207 slides to realize rubbing operation on the softened bottle opening, and in the rubbing process, sealing treatment can be realized, and after rubbing, the first sliding rod 203 moves in a return stroke to break the rubbing part, so that sealing is ensured.
The present invention is not limited to the above-described embodiments, and those skilled in the art will be able to make various modifications without creative efforts from the above-described conception and fall within the scope of the present invention.

Claims (7)

1. An antiserum preparation filling system with CIP and SIP functions comprises a base (1), wherein a box body (101) is fixedly connected to the base (1), a box cover (103) is detachably arranged at one end of the box body (101), and a vacuum processor (104) is arranged on the box cover (103); the method is characterized in that: the fixing part (4) is rotatably arranged in the box body (101), the fixing part (4) comprises an installation cylinder (412), a plurality of fixing holes are formed in the circumference of the installation cylinder (412), the fixing holes are used for placing the bottle body (413), a clamping shell (414) is sleeved on the outer circumference of the installation cylinder (412), and the clamping shell (414) is rotated to fix the bottleneck of the bottle body (413); the fixed part (4) is also provided with a sterilization assembly in a sliding manner, the sterilization assembly comprises a ventilation shell (402), the ventilation shell (402) is of a hollow structure, the inner wall of the ventilation shell (402) is provided with air holes, the number of the air holes is equal to that of the fixed holes in the installation cylinder (412), the air holes are used for spraying steam, and the ventilation shell (402) is also provided with air holes; a sealing component (2) and a filling component (3) are arranged on the base (1), the filling component (3) is used for infusing medicine, and the sealing component (2) is used for sealing the bottle body (413).
2. The CIP, SIP enabled antisera agent filling system according to claim 1, characterized in that: be provided with steam chest (102) on box (101), the inboard sterilization subassembly intercommunication on with fixed part (4) of steam chest (102) to carry out steam and carry, rotary mounting has chassis (106) on base (1), and fixed part (4) are fixed to be set up on chassis (106), and fixed mounting has motor (105) that are used for driving chassis (106) on base (1).
3. A CIP, SIP enabled antisera preparation filling system according to claim 2, characterized in that: the fixing part (4) comprises a fixing column (409) fixedly connected with the chassis (106), and one end of the fixing column (409) is fixedly connected with the mounting cylinder (412); the sterilization assembly comprises a lifting chassis (403) connected with a fixed column (409) in a sliding manner, and two screw rods (404) rotating on the chassis (106), wherein the two screw rods (404) and the lifting chassis (403) form a screw pair; the lifting chassis (403) is rotatably connected with the ventilation shell (402), a rotating cylinder (411) is rotatably arranged on the lifting chassis (403), and a push rod of the rotating cylinder (411) is rotatably connected with the ventilation shell (402).
4. A CIP, SIP enabled antisera preparation filling system according to claim 3, characterized in that: the sterilization assembly further comprises a steam swivel (410) fixedly connected with the fixing column (409), the steam swivel (410) is rotatably connected and communicated with the inner side of the steam box (102), the inner side of the steam swivel (410) is communicated with a steam pipe (401), and one end of the steam pipe (401) is communicated with the ventilation shell (402).
5. The CIP, SIP enabled antisera agent filling system according to claim 1, characterized in that: the filling component (3) comprises a second mounting seat (301) fixedly mounted on the base (1), a second sliding rod (303) is slidably mounted on the second mounting seat (301), and a filling head (304) is arranged at one end of the second sliding rod (303); and a second air cylinder (302) is rotatably arranged on the second mounting seat (301), and a push rod of the second air cylinder (302) is rotatably connected with a second sliding rod (303).
6. The CIP, SIP enabled antisera agent filling system according to claim 1, characterized in that: the sealing component (2) comprises a first mounting seat (202) fixedly mounted on the base (1), a first sliding rod (203) is slidably mounted on the first mounting seat (202), a first air cylinder (201) is rotatably mounted on the first mounting seat (202), and a push rod of the first air cylinder (201) is rotatably connected with the first sliding rod (203); one end of the first sliding rod (203) is connected with two clamping plates (204) in a sliding mode, the two clamping plates (204) are respectively provided with a kneading rod (205), one kneading rod (205) is fixedly connected with the clamping plates (204), and the other kneading rod (205) is connected with the clamping plates (204) in a sliding mode; the two clamping plates (204) are respectively and rotatably connected with a connecting rod (209), and a supporting rod (211) is rotatably connected between the two connecting rods (209); one end of the first sliding rod (203) is fixedly provided with a control cylinder (208), a push rod (212) is fixedly connected to a push rod of the control cylinder (208), a support rod (211) is slidably connected with the push rod of the control cylinder (208), a second spring (210) used for providing elastic force is arranged between the push rod (212) and the push rod of the control cylinder (208), one end of a kneading rod (205) slidably arranged with the clamping plate (204) is fixedly provided with a contact rod (207), and a first spring (206) used for providing elastic force is arranged between the contact rod (207) and the kneading rod (205).
7. A CIP, SIP enabled antisera preparation filling system according to claim 6, characterized in that: a heating device is arranged between the two clamping plates (204).
CN202210867382.2A 2022-07-22 2022-07-22 Antisera preparation filling system with CIP, SIP function Active CN115231013B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210867382.2A CN115231013B (en) 2022-07-22 2022-07-22 Antisera preparation filling system with CIP, SIP function

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Application Number Priority Date Filing Date Title
CN202210867382.2A CN115231013B (en) 2022-07-22 2022-07-22 Antisera preparation filling system with CIP, SIP function

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CN115231013A true CN115231013A (en) 2022-10-25
CN115231013B CN115231013B (en) 2023-08-18

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100866A1 (en) * 2001-11-23 2003-05-29 Duoject Medical Systems Inc. System for filling and assembling pharmaceutical delivery devices
WO2012081489A1 (en) * 2010-12-16 2012-06-21 大日本印刷株式会社 Beverage filling method and machine
CN204661646U (en) * 2015-05-12 2015-09-23 甘孜州康巴尼玛青稞酒业有限公司 To make wine filling mixing disinfection system
CN205668933U (en) * 2016-06-14 2016-11-02 回音必集团(江西)东亚制药有限公司 A kind of plastic bottle washing and sealing machine
CN108839877A (en) * 2018-07-16 2018-11-20 芜湖康奇制药有限公司 A kind of ampoule bottle centrifugal dehumidifier of vitamin b6 injection
CN209940452U (en) * 2019-03-29 2020-01-14 河南万达环保工程有限公司 Full-automatic filling system of bottled water
CN216887308U (en) * 2021-12-09 2022-07-05 长春翔通药业有限公司 Ampoule filling closing device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100866A1 (en) * 2001-11-23 2003-05-29 Duoject Medical Systems Inc. System for filling and assembling pharmaceutical delivery devices
WO2012081489A1 (en) * 2010-12-16 2012-06-21 大日本印刷株式会社 Beverage filling method and machine
CN204661646U (en) * 2015-05-12 2015-09-23 甘孜州康巴尼玛青稞酒业有限公司 To make wine filling mixing disinfection system
CN205668933U (en) * 2016-06-14 2016-11-02 回音必集团(江西)东亚制药有限公司 A kind of plastic bottle washing and sealing machine
CN108839877A (en) * 2018-07-16 2018-11-20 芜湖康奇制药有限公司 A kind of ampoule bottle centrifugal dehumidifier of vitamin b6 injection
CN209940452U (en) * 2019-03-29 2020-01-14 河南万达环保工程有限公司 Full-automatic filling system of bottled water
CN216887308U (en) * 2021-12-09 2022-07-05 长春翔通药业有限公司 Ampoule filling closing device

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