CN115216888A - Wound repair mask dressing and preparation method thereof - Google Patents
Wound repair mask dressing and preparation method thereof Download PDFInfo
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- CN115216888A CN115216888A CN202210950122.1A CN202210950122A CN115216888A CN 115216888 A CN115216888 A CN 115216888A CN 202210950122 A CN202210950122 A CN 202210950122A CN 115216888 A CN115216888 A CN 115216888A
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- 230000037314 wound repair Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title description 7
- 239000000835 fiber Substances 0.000 claims abstract description 64
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 18
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 18
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 18
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 18
- 238000007731 hot pressing Methods 0.000 claims description 20
- 108010081750 Reticulin Proteins 0.000 claims description 13
- 238000005520 cutting process Methods 0.000 claims description 7
- 238000005098 hot rolling Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 238000009960 carding Methods 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000009827 uniform distribution Methods 0.000 claims description 5
- 238000003892 spreading Methods 0.000 claims description 4
- 230000007480 spreading Effects 0.000 claims description 4
- 230000029663 wound healing Effects 0.000 claims description 3
- 239000004744 fabric Substances 0.000 abstract description 12
- 239000007788 liquid Substances 0.000 abstract description 10
- 238000010521 absorption reaction Methods 0.000 abstract description 9
- 230000014759 maintenance of location Effects 0.000 abstract description 6
- 230000002045 lasting effect Effects 0.000 abstract description 3
- 230000000052 comparative effect Effects 0.000 description 7
- 238000012360 testing method Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 231100000263 cytotoxicity test Toxicity 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 230000003833 cell viability Effects 0.000 description 3
- 230000001815 facial effect Effects 0.000 description 3
- 230000003020 moisturizing effect Effects 0.000 description 3
- 239000004745 nonwoven fabric Substances 0.000 description 3
- 230000004537 potential cytotoxicity Effects 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- 229920000433 Lyocell Polymers 0.000 description 2
- 206010053692 Wound complication Diseases 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000036573 scar formation Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 238000012356 Product development Methods 0.000 description 1
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- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 125000000188 beta-D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000002784 cytotoxicity assay Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 230000036548 skin texture Effects 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Images
Classifications
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- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/4382—Stretched reticular film fibres; Composite fibres; Mixed fibres; Ultrafine fibres; Fibres for artificial leather
- D04H1/43835—Mixed fibres, e.g. at least two chemically different fibres or fibre blends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
- D04H1/425—Cellulose series
- D04H1/4258—Regenerated cellulose series
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/44—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties the fleeces or layers being consolidated by mechanical means, e.g. by rolling
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/54—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving
- D04H1/541—Composite fibres, e.g. sheath-core, sea-island or side-by-side; Mixed fibres
- D04H1/5412—Composite fibres, e.g. sheath-core, sea-island or side-by-side; Mixed fibres sheath-core
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/54—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving
- D04H1/542—Adhesive fibres
- D04H1/544—Olefin series
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Textile Engineering (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mechanical Engineering (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
The invention relates to the technical field of mask base cloth, in particular to a wound repair mask dressing which is prepared from 30-70 wt% of carboxymethyl cellulose fiber and the balance of ES fiber. The wound repair mask dressing obtained by the invention has the advantages of high liquid absorption, lasting moisture retention, good skin friendliness and promotion of wound repair.
Description
Technical Field
The invention relates to the technical field of mask base cloth, in particular to a wound repair mask dressing and a preparation method thereof.
Background
The facial mask is second to a clean face as a product with the second use frequency in all skin care product categories of consumers in China. The patch type facial mask is most popular among people because of the effects of instantly moisturizing, brightening the skin and improving the skin texture.
If an ideal using effect is to be achieved, in the product development process, not only the raw materials need to be carefully selected and the force needs to be given in the matching process, but also the compatibility and the compatibility between the mask base cloth and the mask essence need to be kept.
At present, the mask base cloth in the market mainly uses cotton fibers, viscose terylene, cuprammonium fibers, tencel and menthol fibers as raw materials. However, the indexes of the mask base cloth prepared from the raw materials, such as liquid absorption amount, moisture retention, skin-friendly property, fitting property and the like, are difficult to meet the use requirements at the same time, and the mask base cloth does not have the wound repair effect.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the wound repair mask dressing which is prepared from carboxymethyl cellulose fibers and ES fibers and has the advantages of high liquid absorption, lasting moisture retention, good skin friendliness and promotion of wound repair.
In order to realize the purpose, the invention adopts the following technical scheme:
a wound repair mask dressing is prepared from 30-70 wt% of carboxymethyl cellulose fiber and the balance ES fiber.
Optionally, the paint comprises the following components in percentage by weight: 50% of carboxymethyl cellulose fiber and 50% of ES fiber.
The invention also aims to provide a preparation method of the wound repair mask dressing, which comprises the following steps:
(1) Cutting the carboxymethyl cellulose fiber and the ES fiber according to the required length respectively, and sterilizing;
(2) Mixing the sterilized carboxymethyl cellulose fiber and ES fiber according to a weight ratio, and then putting the mixture into a feeder for carding, opening and removing impurities;
(3) Uniformly laying the carded fibers on a net forming curtain through a lapping machine to prepare the reticular fibers with uniform thickness and uniform distribution;
(4) Hot-pressing the reticular fibers by a hot rolling mill according to the set temperature and pressure;
(5) And (3) cutting edges of the fibers subjected to hot pressing, counting the length of the fibers, and mechanically curling the fibers to obtain the wound repair mask dressing.
Optionally, the hot pressing temperature in the step (4) is 120-160 ℃.
Optionally, the hot pressing pressure in the step (4) is 0.3-1 Mpa.
The molecular main stem of the carboxymethyl cellulose fiber is a long chain formed by connecting 1000-10000 beta-D glucoses through 1, 4-glycosidic bonds, and contains a large number of hydrophilic groups, namely hydroxyl (-OH) and carboxyl (-COOH). The semi-solid gel can be formed after meeting water at normal temperature, and when microorganisms in a motion state meet carboxymethyl cellulose fibers of the semi-solid gel, the microorganisms are immediately bound to seal the proliferation function of pathogenic microorganisms, so that the purpose of bacteriostasis is achieved. Is beneficial to the dissolution of fibrin and necrotic tissues, promotes the release and activity of various growth factors, and promotes the growth of epithelial cells and the generation of capillary vessels. Thereby achieving the aims of promoting wound healing, relieving wound pain and reducing scar formation.
The ES fiber is a novel thermal bonding composite fiber, is a bicomponent sheath-core structure composite fiber, and has low melting point and good flexibility of a sheath tissue and high melting point and high strength of a core tissue. After heat treatment, part of the skin layer is melted to play a role of bonding, and the rest of the skin layer still keeps the state of mutual adhesion of fibers and fibers, so that a non-woven fabric forming body without a binder can be formed, and meanwhile, the non-woven fabric forming body has the characteristic of small heat shrinkage rate, and a high-strength non-woven fabric can be obtained by adopting a hot rolling bonding mode.
Compared with the prior art, the invention has the following advantages: 1) Promoting wound healing, relieving wound pain, and reducing scar formation; 2) The skin-friendly property is good, the allergy rate is low, and the skin-friendly cream is suitable for any skin type; 3) High liquid absorption amount and lasting moisture preservation; 4) Light weight, thin body and high strength.
Drawings
Fig. 1 is a graph of in vitro cytotoxicity test data of a wound repair mask dressing.
Detailed Description
The invention is further described below with reference to examples, but the scope of the invention as claimed is not limited to the scope of the examples.
Example 1
A preparation method of the wound repair mask dressing comprises the following steps:
(1) Respectively putting carboxymethyl cellulose fibers and ES fibers into a splitting machine to be split according to the required length, and transferring the split fibers to an oven at 80 ℃ for sterilization;
(2) Mixing 30KG sterilized carboxymethyl cellulose fiber and 70KG ES fiber, and putting the mixture into a feeder for carding, opening and removing impurities;
(3) Uniformly spreading the carded fibers on a net forming curtain through a lapping machine to prepare the reticular fibers with consistent thickness and uniform distribution;
(4) Setting the hot pressing temperature at 120 ℃ and the hot pressing pressure at 0.3Mpa, and hot-pressing the reticular fibers by using a hot rolling mill to form the reticular fibers, wherein the forming thickness is 0.1-0.15 mm, and the pressing time is 3s;
(5) And (4) cutting edges of the fibers subjected to hot pressing, measuring the length of the fibers, and mechanically curling the fibers to obtain the wound repair mask dressing.
Example 2
A preparation method of the wound repair mask dressing comprises the following steps:
(1) Respectively putting carboxymethyl cellulose fibers and ES fibers into a splitting machine to be split according to required lengths, and transferring the split fibers to an oven at 80 ℃ for sterilization;
(2) Mixing the sterilized carboxymethyl cellulose fiber 50KG and ES fiber 50KG, and then putting the mixture into a feeder to carry out carding, opening and impurity removal;
(3) Uniformly spreading the carded fibers on a net forming curtain through a lapping machine to prepare the reticular fibers with consistent thickness and uniform distribution;
(4) Setting the hot-pressing temperature at 130 ℃ and the hot-pressing pressure at 0.5Mpa, and hot-pressing the reticular fibers by using a hot rolling mill to form the reticular fibers, wherein the forming thickness is 0.1-0.15 mm, and the pressing time is 3s;
(5) And (3) cutting edges of the fibers subjected to hot pressing, counting the length of the fibers, and mechanically curling the fibers to obtain the wound repair mask dressing.
Example 3
A preparation method of the wound repair mask dressing comprises the following steps:
(1) Respectively putting carboxymethyl cellulose fibers and ES fibers into a splitting machine to be split according to required lengths, and transferring the split fibers to an oven at 80 ℃ for sterilization;
(2) Mixing the sterilized carboxymethyl cellulose fiber 70KG and ES fiber 30KG, and then putting the mixture into a feeder for carding, opening and removing impurities;
(3) Uniformly spreading the carded fibers on a net forming curtain through a lapping machine to prepare the reticular fibers with consistent thickness and uniform distribution;
(4) Setting the hot pressing temperature at 160 ℃ and the hot pressing pressure at 1Mpa, and hot-pressing the reticular fibers by using a hot rolling mill to form the reticular fibers, wherein the forming thickness is 0.1-0.15 mm, and the pressing time is 3s;
(5) And (4) cutting edges of the fibers subjected to hot pressing, measuring the length of the fibers, and mechanically curling the fibers to obtain the wound repair mask dressing.
Comparative example 1
A commercial silk mask base cloth.
Comparative example 2
A commercial tencel mask base cloth.
Comparative example 3
The pure cotton fiber mask base cloth is sold in the market.
The wound repair mask dressings obtained in examples 1 to 3 and the mask base cloths in comparative examples 1 to 3 were punched into normal mask sizes of the same shape, and weight, liquid absorption amount, and moisturizing duration tests were performed to obtain data in table 1.
Weight test: and respectively weighing the weight of the single-layer mask base cloth by using an electronic balance.
Liquid absorption test: immersing the mask base cloth in pure water for 10min, taking out, suspending until no liquid dripping, and weighing the liquid-absorbed weight.
Moisturizing duration test: applying the liquid-absorbed facial mask base cloth on face, and comparing moisture retention time every 2 min.
Table 1:
| group of | Is the weight g of liquid absorption | Weight g after imbibition | Moisture retention time min | Liquid absorption volume% |
| Example 1 | 0.71 | 22.32 | 40 | 3044％ |
| Example 2 | 0.70 | 27.02 | 46 | 3760％ |
| Example 3 | 0.71 | 31.51 | 48 | 4338％ |
| Comparative example 1 | 0.82 | 10.78 | 26 | 1215％ |
| Comparative example 2 | 0.88 | 10.63 | 22 | 1108％ |
| Comparative example 3 | 0.83 | 9.58 | 24 | 1054％ |
From table 1, it can be seen that the wound repair mask dressing of the present invention is not only light (more than 12% light in the same shape), but also has a liquid absorption amount of more than 3000% (much higher than 1000%), and the moisture retention time is almost doubled.
In vitro cytotoxicity assay
The wound repair mask dressing obtained in example 2 was subjected to in vitro cytotoxicity test.
The test reference standard is: ISO 10993-5: in vitro cytotoxicity test, MTT method was used to evaluate the potential cytotoxicity of the samples, and the data in FIG. 1 were obtained.
The evaluation criteria were: the lower the% cell viability, the greater the potential cytotoxicity; cell viability < blank 70%, indicating potential cytotoxicity of the sample; the% cell viability of the 100% test sample extract is the final result.
As can be seen from fig. 1, the leaching solution (cell activity 90.9%) of the wound repair mask dressing of the present invention has no potential toxic effect on cells.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and adaptations to those skilled in the art without departing from the principles of the present invention should also be considered as within the scope of the present invention.
Claims (5)
1. The wound repair mask dressing is characterized by being prepared from 30-70 wt% of carboxymethyl cellulose fibers and the balance of ES fibers.
2. A wound repair mask dressing according to claim 1, consisting of, in weight percent: 50% of carboxymethyl cellulose fiber and 50% of ES fiber.
3. A method of preparing a wound healing mask dressing according to claim 1 or 2, comprising the steps of:
(1) Cutting the carboxymethyl cellulose fiber and the ES fiber according to the required length respectively, and sterilizing;
(2) Mixing the sterilized carboxymethyl cellulose fibers and ES fibers according to a weight ratio, putting the mixture into a feeder, and carding, opening and removing impurities;
(3) Uniformly spreading the carded fibers on a net forming curtain through a lapping machine to prepare the reticular fibers with consistent thickness and uniform distribution;
(4) Hot-pressing the reticular fibers by a hot rolling mill according to the set temperature and pressure;
(5) And (3) cutting edges of the fibers subjected to hot pressing, counting the length of the fibers, and mechanically curling the fibers to obtain the wound repair mask dressing.
4. A method for preparing a wound repair mask dressing according to claim 3, wherein the hot pressing temperature in step (4) is 120-160 ℃.
5. A method for preparing a wound repair mask dressing according to claim 3, wherein the hot pressing pressure in step (4) is 0.3-1 Mpa.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210950122.1A CN115216888A (en) | 2022-08-09 | 2022-08-09 | Wound repair mask dressing and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210950122.1A CN115216888A (en) | 2022-08-09 | 2022-08-09 | Wound repair mask dressing and preparation method thereof |
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| CN103463670A (en) * | 2013-09-18 | 2013-12-25 | 佛山市优特医疗科技有限公司 | Wound dressing containing fibers with low smelting point and production method thereof |
| CN107569320A (en) * | 2017-07-11 | 2018-01-12 | 佛山市优特医疗科技有限公司 | A kind of wound dressing of reinforcement and preparation method thereof |
| CN109733024A (en) * | 2017-10-30 | 2019-05-10 | 湖北智权专利技术应用开发有限公司 | A kind of antibacterial thermal non-woven fabric |
| CN113813107A (en) * | 2021-09-16 | 2021-12-21 | 惠州华阳医疗器械有限公司 | Dressing and preparation method thereof |
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Application publication date: 20221021 |