CN115211517A - Solid beverage with uric acid reducing effect and preparation method thereof - Google Patents

Solid beverage with uric acid reducing effect and preparation method thereof Download PDF

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Publication number
CN115211517A
CN115211517A CN202210935322.XA CN202210935322A CN115211517A CN 115211517 A CN115211517 A CN 115211517A CN 202210935322 A CN202210935322 A CN 202210935322A CN 115211517 A CN115211517 A CN 115211517A
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vitamin
powder
extract
parts
uric acid
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王克祥
董琳琳
王娜
王随国
于娅萍
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Xinxiang Lvjianyuan Medicine And Food Homology Research Institute Co ltd
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Xinxiang Lvjianyuan Medicine And Food Homology Research Institute Co ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Non-Alcoholic Beverages (AREA)

Abstract

The invention discloses a solid beverage with uric acid reducing effect and a preparation method thereof, and the solid beverage is prepared by weighing: erythritol, diglyceride oil powder, celery seed powder, celery juice powder, lophatherum gracile extract, corn stigma extract, blueberry extract, green tea extract, marine fish oligopeptide, sour cherry fruit powder, acer truncatum seed oil microcapsule powder, edible essence, sucrose fatty acid ester, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12 and sucralose; pre-mixing and total mixing; and finally, subpackaging. The invention can inhibit the absorption and transformation of purine in the body, promote purine to be discharged out of the body along with urine, and has obvious effects of reducing uric acid and preventing gout.

Description

Solid beverage with uric acid reducing effect and preparation method thereof
Technical Field
The invention belongs to the field of health-care food, and particularly relates to a solid beverage with a uric acid reducing effect and a preparation method thereof.
Background
Hyperuricemia (HUA) refers to a condition of two fasting blood uric acid levels higher than 420. Mu. Mol/L in men and higher than 360. Mu. Mol/L in women under normal purine diet, which is called hyperuricemia. With the improvement of living standard and the change of eating habit of people, the incidence of hyperuricemia in China is on the trend of increasing year by year and the trend of younger year. Uric acid is a terminal metabolite of purine compounds metabolism in humans, and hyperuricemia is a metabolic disorder syndrome caused by purine metabolic disorders. When the blood uric acid exceeds the saturation degree of the blood uric acid in blood or tissue fluid, sodium urate crystals can be formed and deposited on the local joints, so that organ and tissue diseases of a human body are caused, gout is caused, and serious complications are caused, including gouty arthritis, gouty kidney disease, gouty kidney stone, gouty heart disease, gouty hypertension and the like.
In clinical treatment of hyperuricemia, western medicines mainly use analgesic and anti-inflammatory medicines to temporarily relieve pain. Such as febuxostat, allopurinol, colchicine, benzbromarone, probenecid and the like. In the final step of purine metabolism, hypoxanthine is generated into xanthine under the action of Xanthine Oxidoreductase (XOR), and then uric acid is further generated, and febuxostat and allopurinol are inhibitors of the xanthine oxidoreductase, and the two drugs are highly selectively acted on the oxidase to reduce the synthesis of uric acid in vivo and reduce the concentration of uric acid, so that gout is effectively treated. Colchicine has analgesic effect by reducing leukocyte activity and phagocytosis and reducing lactic acid formation to reduce uric acid crystal deposition and relieve inflammatory reaction. Benzbromarone and probenecid reduce the concentration of urate in blood by inhibiting the active reabsorption of urate by renal tubules, increasing the excretion of urate, alleviating or preventing the formation of urate nodules, reducing the injury of alleviation, and promoting the dissolution of urate that has formed. Although the medicines have better curative effect on gout, certain toxic and side effects are shown in clinic. Among them, the adverse reactions of febuxostat include abnormal liver function, diarrhea, headache, joint-related symptoms and symptoms, and musculoskeletal connective tissue symptoms. The allopurinol has the adverse reactions of common skin rash, diarrhea and abdominal pain, low fever, temporary transaminase rise or granulocytopenia and the like. Colchicine is extremely toxic, and is commonly seen in nausea, vomiting, diarrhea, abdominal pain, gastrointestinal reaction, hematuria and oliguria, has direct inhibition effect on bone marrow, causes agranulocytosis, aplastic anemia and the like. Benzbromarone can cause granulocytopenia. Probenecid is common in adverse reactions such as gastrointestinal reaction, rash, fever and the like, and the long-term use of the drugs brings great pain to patients, threatens health and influences life quality.
The traditional Chinese medicine causes of gout: 1. yang exuberance of the body and accumulated toxicity in zang-fu organs. Heat accumulation in the zang-fu organs is a prerequisite for forming toxic pathogen to attack the bone joint, and long-term heat accumulation, heat stagnation as toxin is the root cause of gout. 2. Damp-heat and turbid-toxin remained in the joints. Dampness-heat and turbidity-toxin, which is rooted in the spleen and stomach, stagnates meridians, blocks meridians and collaterals, flows into joints, and if the healthy qi is deficient and pathogenic factors lingers, the dampness-toxin is not removed, it flows through the meridians and attaches to the bone joints to form the phlegm-stone which is hard like the stone. Therefore, damp-heat and turbid-toxin are the main causes of the formation of tophus. 3. Spleen deficiency is the principal and dampness-turbidity is the secondary. The deficient spleen and stomach, together with improper diet, can impair the spleen and stomach, cause disorders of transportation and transformation, induce damp turbidity, and cause diseases of the body by injecting into the skin, flesh and joints and leaving viscera inside. 4. Invasion of exogenous pathogenic factors can lead to retention of exogenous pathogenic factors. Muscle joints cause unsmooth qi and blood, blockage of channels and collaterals, and pain due to blockage, which can cause deficiency of qi and blood, blood heat causing stasis, and obstruction of channels and collaterals, and cause arthrocele, deformity and stiffness. The Chinese medicine needs to classify symptoms for treating hyperuricemia and gout, and cannot achieve universality.
Hyperuricemia and gout are a continuous, chronic pathophysiological process, so that management of hyperuricemia and gout should also be a continuous process, and long-term and even lifetime condition monitoring and management is required. The functional food capable of reducing uric acid is reasonably selected, the generation of uric acid of a human body is controlled by daily drinking, the blood uric acid is reduced, the occurrence of hyperuricemia and gout is reduced, and the health care tea is safe and has no toxic or side effect.
Disclosure of Invention
The invention aims to provide a solid beverage with the efficacy of reducing uric acid and a preparation method thereof, which can solve the problems in the background art.
The invention relates to a solid beverage with uric acid reducing effect, which is characterized in that: the raw materials and the parts by weight are as follows: 20-50 parts of erythritol, 10-50 parts of diglyceride oil powder, 10-50 parts of celery seed powder, 5-50 parts of celery juice powder, 1-20 parts of lophatherum gracile extract, 1-20 parts of corn stigma extract, 1-20 parts of blueberry extract, 0.1-2 parts of green tea extract, 1-10 parts of marine fish oligopeptide, 0.01-1 part of sour cherry fruit powder, 0.001-1 part of acer truncatum seed oil microcapsule powder, 0.001-1 part of edible essence, 0.001-1 part of sucrose fatty acid ester, 0.01-1 part of vitamin E, 0.001-1 part of vitamin B1, 0.001-1 part of vitamin B2, 0.001-1 part of vitamin B6, 0.000000001-1 part of vitamin B and 0.001-1 part of sucralose.
The diglyceride oil powder comprises at least one of diglyceride microcapsule powder, diglyceride embedded powder and diglyceride oil powder. The diglyceride powder can reduce the Xanthine Oxidase (XOD) activity of serum and liver, and can reduce the expression level of renal cortical uric acid Transporter1 (URAT 1), thereby inhibiting xanthine generation and further reducing uric acid formation.
The celery seed powder comprises at least one of celery seed powder and celery seed extract. The celery seed is seed of Apium graveolens of Umbelliferae, contains abundant vitamins and volatile aromatic components, contains phthalides with obvious uric acid reducing and pain relieving effects, and is an active ingredient for resisting gout.
The celery juice powder comprises at least one of celery powder, celery juice powder and celery juice extract. Celery is Apium graveolens belonging to Umbelliferae, and contains apigenin which can reduce Serum Uric Acid (SUA) level by inhibiting in vivo Adenosine Dehydrogenase (ADA) activity, and further reduce Uric Acid formation
The sour cherry powder comprises at least one of sour cherry powder, sour cherry juice powder and sour cherry extract. Sour cherry is also called prunus cerasus, and is a fruit of prunus cerasifera which is native to europe. It is rich in anthocyanidin, and has effects of inhibiting Xanthine Oxidase (XOD) and reducing uric acid formation.
The acer truncatum seed oil powder comprises at least one of acer truncatum seed oil powder, acer truncatum seed oil embedding powder and acer truncatum seed oil microcapsule powder. Acer truncatum seed oil is prepared from seed of Acer truncatum Bunge of Aceraceae of Sapindales, and is a new resource food with effects of regulating immunity, increasing NK cell activity, and improving organism cellular immunity and humoral immunity.
The lophatherum gracile extract, the corn stigma extract, the blueberry extract and the green tea extract are dried substances obtained by a water extraction process. Lophatherum gracile is the dried stem and leaf of Lophatherum gracile of Gramineae. Being sweet, bland and cold in nature and good in property, it enters heart, small intestine and bladder meridians, and can clear heart fire, relieve restlessness, induce diuresis and treat stranguria. The stigma Maydis is flower column and flower head of Gramineae plant semen Maydis. Sweet taste and slightly warm nature. Enter bladder, liver and gallbladder meridians. It has the functions of inducing diuresis to reduce edema, clearing away liver heat and promoting bile flow. The blueberry is fruit of blueberries of Vaccinium of Ericaceae, contains abundant anthocyanin, and has effects of inhibiting Xanthine Oxidase (XOD) and reducing uric acid formation. The green tea has good antioxidant and tranquilizing effects, and can relieve fatigue. Green tea is rich in vitamin C and flavonoids. In addition, green tea powder has promoting effects on relieving constipation, reducing weight, beautifying body and reducing weight.
The vitamin E comprises at least one of vitamin E powder, coating vitamin E powder, vitamin E microcapsule powder and vitamin E embedding powder. Vitamin E, also known as tocopherol or gestagen, is one of the most important antioxidants. Vitamin E can protect the stability of cell membrane by interrupting the chain reaction of free radicals, regulate the normal secretion of hormone in vivo, prevent LDL cholesterol from being oxidized, and has synergistic effect with other vitamins.
The vitamin B1, the vitamin B2, the vitamin B6 and the vitamin B12 comprise at least one of vitamin B1 powder, vitamin B2 powder, vitamin B6 powder, vitamin B12 powder, vitamin B1 embedding powder, vitamin B2 embedding powder, vitamin B6 embedding powder, vitamin B12 powder, vitamin B1 microcapsule powder, vitamin B2 microcapsule powder, vitamin B6 microcapsule powder and vitamin B12 microcapsule powder. Vitamin B1, vitamin B2, vitamin B6 and vitamin B12 belong to the vitamin B group and are necessary rings for metabolism in the body, and the components cooperate to help the metabolism of saccharides, fat and protein to release energy.
The marine fish oligopeptide is a dried product obtained by carrying out enzymolysis on marine fish. The marine fish oligopeptide is called as marine fish collagen peptide, and researches show that when a certain amount of marine and oligopeptide acts on a human body, the quantity of HPRT enzyme and LDH can be increased, so that purine substances can be effectively prevented from being retained in the body, the content of uric acid is reduced, and uric acid crystals at joints are dissolved.
A preparation method of a solid beverage with the efficacy of reducing uric acid is characterized by comprising the following steps:
(1) Weighing: erythritol, diglyceride oil powder, celery seed powder, celery juice powder, lophatherum gracile extract, corn stigma extract, blueberry extract, green tea extract, marine fish oligopeptide, sour cherry fruit powder, acer truncatum seed oil microcapsule powder, edible essence, sucrose fatty acid ester, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12 and sucralose can be accurately weighed according to required materials; the specific weighing value refers to the value range of claim 1;
(2) Premixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by a V-shaped mixer for 30-40 minutes at normal temperature, wherein the loading amount of the edible essence is not more than 50% of the volume of the mixer; carrying out premixing;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is not more than 75 percent of the volume of the mixer, and mixing for 30-40 minutes at normal temperature;
(4) Subpackaging: and packaging the total mixed materials into products of 5-15 g/bag.
The beneficial effects of the invention are: unsaturated lipids, peptides, vitamins, new resource food and food raw materials which are homologous in medicine and food are matched with each other to regulate functions of each system of a human body, so that functions of internal organs of the human body are normal, damaged cells are repaired, immunity is improved, the effects of inducing diuresis and clearing damp are enhanced, heat and toxic materials are removed, dampness is removed, diuresis is induced, meridians are dredged to relieve pain, yin and yang are balanced, the excretion function of the body is improved, absorption and transformation of purine in the body are inhibited, purine is promoted to be discharged out of the body along with urine, the effects of reducing uric acid and preventing gout are obvious, and other uncomfortable symptoms are eliminated.
Detailed Description
The present invention will be described in detail with reference to examples.
In the case of the example 1, the following examples are given,
a preparation method of a solid beverage with uric acid reducing effect comprises the following steps:
(1) Weighing: the raw materials can be accurately weighed according to the required materials, and the raw materials comprise, by weight, 20 parts of erythritol, 10 parts of diglyceride oil powder, 15 parts of celery seed powder, 20 parts of celery juice powder, 1 part of lophatherum gracile extract, 1 part of corn stigma extract, 1 part of blueberry extract, 0.1 part of green tea extract, 1 part of marine fish oligopeptide, 0.01 part of sour cherry powder, 0.001 part of acer truncatum seed oil microcapsule powder, 0.001 part of edible essence, 0.001 part of sucrose fatty acid ester, 0.01 part of vitamin E, 0.001 part of vitamin B2, 0.001 part of vitamin B6, 0.00001 part of vitamin B12 and 0.001 part of sucralose;
(2) Pre-mixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by adopting a V-shaped mixer, wherein the charging amount of the V-shaped mixer is 50 percent of the volume of the mixer, and premixing for 30 minutes at normal temperature;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is 75 percent of the volume of the mixer, and mixing for 30 minutes at normal temperature;
(4) Subpackaging: and packaging the total mixed materials into products of 5 g/bag.
In the case of the example 2, the following examples are given,
a preparation method of a solid beverage with the efficacy of reducing uric acid comprises the following steps:
(1) Weighing: the feed additive can be accurately weighed according to the required materials, and comprises, by weight, 50 parts of erythritol, 50 parts of diglyceride oil powder, 50 parts of celery seed powder, 50 parts of celery juice powder, 20 parts of lophatherum gracile extract, 20 parts of corn stigma extract, 20 parts of blueberry extract, 2 parts of green tea extract, 10 parts of marine fish oligopeptide, 1 part of sour cherry fruit powder, 1 part of acer truncatum seed oil microcapsule powder, 1 part of edible essence, 1 part of sucrose fatty acid ester, 1 part of vitamin E, 1 part of vitamin B2, 6 parts of vitamin B, 12 parts of vitamin B and 1 part of sucralose;
(2) Pre-mixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by adopting a V-shaped mixer, wherein the loading amount of the V-shaped mixer is 49 percent of the volume of the mixer, and premixing for 36 minutes at normal temperature;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount of the premixed materials is 70% of the volume of the mixer, and mixing for 38 minutes at normal temperature;
(4) Subpackaging: and packaging the total mixed materials into products of 10 g/bag.
In the case of the embodiment 3, the following examples,
a preparation method of a solid beverage with uric acid reducing effect comprises the following steps:
(1) Weighing: the feed additive can be accurately weighed according to the required materials, and comprises, by weight, 30 parts of erythritol, 30 parts of diglyceride oil powder, 10 parts of celery seed powder, 5 parts of celery juice powder, 10 parts of lophatherum gracile extract, 10 parts of corn stigma extract, 10 parts of blueberry extract, 1 part of green tea extract, 5 parts of marine fish oligopeptide, 0.5 part of sour cherry fruit powder, 0.5 part of acer truncatum seed oil microcapsule powder, 0.5 part of edible essence, 0.5 part of sucrose fatty acid ester, 0.5 part of vitamin E, 0.5 part of vitamin B1, 0.5 part of vitamin B2, 0.4 part of vitamin B6, 0.00005 part of vitamin B12 and 0.5 part of sucralose;
(2) Premixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by adopting a V-shaped mixer, wherein the charging amount of the V-shaped mixer is 48 percent of the volume of the mixer, and premixing for 40 minutes at normal temperature;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is 72 percent of the volume of the mixer, and mixing for 40 minutes at normal temperature;
(4) Subpackaging: and packaging the mixed materials into 9 g/bag of products.
In the case of the example 4, the following examples are given,
a preparation method of a solid beverage with the efficacy of reducing uric acid comprises the following steps:
(1) Weighing: the health-care food can be accurately weighed according to the required materials, and comprises, by weight, 40 parts of erythritol, 22 parts of diglyceride oil powder, 26 parts of celery seed powder, 35 parts of celery juice powder, 12 parts of lophatherum gracile extract, 13 parts of corn stigma extract, 14 parts of blueberry extract, 0.8 part of green tea extract, 8 parts of marine fish oligopeptide, 0.18 part of sour cherry fruit powder, 0.29 part of acer truncatum seed oil micro-capsule powder, 0.008 part of edible essence, 0.009 part of sucrose fatty acid ester, 0.1 part of vitamin E, 0.2 part of vitamin B, 0.08 part of vitamin B, 0.07 part of vitamin B, 0.0007 part of vitamin B and 0.09 part of sucralose;
(2) Premixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by adopting a V-shaped mixer, wherein the loading amount of the V-shaped mixer is 50 percent of the volume of the mixer, and premixing for 32 minutes at normal temperature;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is 73 percent of the volume of the mixer, and mixing for 37 minutes at normal temperature;
(4) Subpackaging: and packaging the mixed materials into 8 g/bag of products.
In the case of the example 5, the following examples were conducted,
a preparation method of a solid beverage with uric acid reducing effect comprises the following steps:
(1) Weighing: the raw materials can be accurately weighed according to the required parts by weight, 35 parts of erythritol, 32 parts of diglyceride oil powder, 47 parts of celery seed powder, 40 parts of celery juice powder, 8 parts of lophatherum gracile extract, 7 parts of corn stigma extract, 5 parts of blueberry extract, 1.8 parts of green tea extract, 4 parts of marine fish oligopeptide, 0.98 part of sour cherry fruit powder, 0.05 part of acer truncatum seed oil microcapsule powder, 0.08 part of edible essence, 0.06 part of sucrose fatty acid ester, 0.04 part of vitamin E, 0.35 part of vitamin B, 0.57 part of vitamin B, 0.39 part of vitamin B, 0.00008 part of vitamin B and 0.22 part of sucralose;
(2) Premixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by adopting a V-shaped mixer, wherein the charging amount of the V-shaped mixer is 49 percent of the volume of the mixer, and premixing for 37 minutes at normal temperature;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is 74 percent of the volume of the mixer, and mixing for 36 minutes at normal temperature;
(4) Subpackaging: and (4) packaging the mixed materials into products of 15 g/bag.
The scheme of the invention is used, and the person with higher uric acid is selected for practical use, and the recording and the effect evaluation are carried out as follows:
clinically, the normal values of male uric acid: 149-416 mol/L, if exceeding the index, belonging to hyperuricemia. 20 male hyperuricemia volunteers were randomly collected, and the blood uric acid was above 420 mol/L. The uric acid reducing solid beverage in the embodiment 1 of the invention is orally taken every day, one packet is taken every time, and the solid beverage is taken twice a day.
Criteria for therapeutic effect
The composition is administered continuously for 20 days, and the blood uric acid is reduced by more than 100mol/L after administration compared with before administration.
The composition is administered continuously for 20 days, and the blood uric acid is reduced by less than 100mol/L after administration.
The composition is administered continuously for 20 days, and the blood uric acid is reduced by less than 20mol/L after administration
Therapeutic efficacy analysis and statistics
Figure BDA0003783269010000101
Figure BDA0003783269010000111
From the results, the scheme of the invention can effectively and rapidly reduce the uric acid level, and after eating for 20 days, the effective cases account for 60%, the effective cases account for 35%, the ineffective cases account for 5%, and the total effective rate for reducing uric acid is 95%.
The tests prove that the solid beverage and the preparation method thereof provided by the invention are more scientific, reasonable and healthy and have good using effect. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features related to the embodiments of the present invention described above may be combined with each other as long as they do not conflict with each other. In addition, the above embodiments are only some embodiments of the present invention, not all embodiments, and all other embodiments obtained by those skilled in the art based on the embodiments of the present invention without any creative work belong to the protection scope of the present invention.

Claims (2)

1. A solid beverage with uric acid reducing effect is characterized in that: the raw materials and the parts by weight are as follows:
20-50 parts of erythritol, 10-50 parts of diglyceride oil powder, 10-50 parts of celery seed powder, 5-50 parts of celery juice powder, 1-20 parts of lophatherum gracile extract, 1-20 parts of corn stigma extract, 1-20 parts of blueberry extract, 0.1-2 parts of green tea extract, 1-10 parts of marine fish oligopeptide, 0.01-1 part of sour cherry fruit powder, 0.001-1 part of acer truncatum seed oil microcapsule powder, 0.001-1 part of edible essence, 0.001-1 part of sucrose fatty acid ester, 0.01-1 part of vitamin E, 0.001-1 part of vitamin B1, 0.001-1 part of vitamin B2, 0.001-1 part of vitamin B6, 0.000000001-1 part of vitamin B and 0.001-1 part of sucralose.
2. A preparation method of a solid beverage with uric acid reducing effect is characterized by comprising the following steps:
(1) Weighing: erythritol, diglyceride oil powder, celery seed powder, celery juice powder, lophatherum gracile extract, corn stigma extract, blueberry extract, green tea extract, marine fish oligopeptide, sour cherry fruit powder, acer truncatum seed oil microcapsule powder, edible essence, sucrose fatty acid ester, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12 and sucralose, wherein the erythritol, the diglyceride oil powder, the celery seed powder, the lophatherum gracile extract, the corn stigma extract, the blueberry extract, the green tea extract, the marine fish oligopeptide, the sour cherry fruit powder, the acer truncatum seed oil microcapsule powder and the sucralose are accurately weighed according to required materials; the specific weighing value refers to the value range of claim 1;
(2) Pre-mixing: premixing edible essence, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin B12, sucralose and sucrose fatty acid ester by a V-shaped mixer at normal temperature for 30-40 minutes, wherein the loading amount of the edible essence is not more than 50% of the volume of the mixer;
(3) Total mixing: putting the rest materials and the premixed materials into a three-dimensional motion mixer, wherein the loading amount is not more than 75 percent of the volume of the mixer, and mixing for 30-40 minutes at normal temperature;
(4) Subpackaging: and packaging the total mixed materials into products of 5-15 g/bag.
CN202210935322.XA 2022-08-05 2022-08-05 Solid beverage with uric acid reducing effect and preparation method thereof Pending CN115211517A (en)

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CN109452521A (en) * 2018-12-26 2019-03-12 广东养慕特殊医用食品有限公司 A kind of anti-trioxypurine peptide solid beverage, Preparation method and use
CN109758571A (en) * 2019-03-27 2019-05-17 长春健康未来医药科技有限公司 A kind of promotion uric acid metabolism improves gout, the composition of Saving cortilage and preparation method thereof
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CN108391774A (en) * 2018-05-25 2018-08-14 张瑞雪 A kind of drinks of antigout and preparation method thereof
CN109452521A (en) * 2018-12-26 2019-03-12 广东养慕特殊医用食品有限公司 A kind of anti-trioxypurine peptide solid beverage, Preparation method and use
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