CN115165430A - Tumor sampling device convenient for tumor separation - Google Patents

Tumor sampling device convenient for tumor separation Download PDF

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Publication number
CN115165430A
CN115165430A CN202210639813.XA CN202210639813A CN115165430A CN 115165430 A CN115165430 A CN 115165430A CN 202210639813 A CN202210639813 A CN 202210639813A CN 115165430 A CN115165430 A CN 115165430A
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CN
China
Prior art keywords
tumor
sampling
barrel
sampling device
handheld
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Withdrawn
Application number
CN202210639813.XA
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Chinese (zh)
Inventor
张廷友
李小芳
王晓娟
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Second Affiliated Hospital of Zunyi Medical University
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Second Affiliated Hospital of Zunyi Medical University
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Application filed by Second Affiliated Hospital of Zunyi Medical University filed Critical Second Affiliated Hospital of Zunyi Medical University
Priority to CN202210639813.XA priority Critical patent/CN115165430A/en
Publication of CN115165430A publication Critical patent/CN115165430A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a tumor sampling device convenient for separating tumors, which comprises a supporting mechanism, wherein a fixing mechanism for clamping and fixing a tumor sample and a sampling mechanism arranged on the inner side of the supporting mechanism and used for sampling the tumor sample are arranged on the lower side of the supporting mechanism, and the sampling mechanism and the fixing mechanism are connected with the supporting mechanism; the supporting mechanism comprises a handheld barrel, the lower end of the handheld barrel is provided with a supporting ring, the supporting ring is in an annular shape, the lower end of the inner side of the supporting ring is provided with an annular wall, the upper end face of the supporting ring is evenly provided with a through groove, a slide way is arranged on the side wall of the handheld barrel, and a barrel cover is arranged at the upper end of the handheld barrel. The tumor sample is clamped and fixed by the fixing mechanism, and then the tumor sample entering the sampling cylinder is cut by the rotary cutter of the sampling mechanism, so that the sample is taken out after being moved out in the sealed space, the sample is prevented from falling off when being moved out, and the sampling operation is improved.

Description

Tumor sampling device convenient for tumor separation
Technical Field
The invention relates to the field of medical treatment, in particular to a tumor sampling device convenient for tumor separation.
Background
The tumor is a new organism formed by local tissue cell proliferation under the action of various tumorigenic factors, and because the new organism mostly presents space-occupying blocky bulges and is also called as neoplasms, researches show that the tumor cells can generate metabolic changes different from normal cells, and meanwhile, the tumor cells can adapt to the change of metabolic environment through the conversion between glycolysis and oxidative phosphorylation.
At present, lung cancer is one of the most common malignant tumors in China, and scientific research on lung cancer in China is actively carried out in units throughout the country, so that lung cancer tissue specimens obtained through operations become a resource at the core of scientific research.
The tumour need use sampling device to take a sample after the excision, is convenient for follow-up carry out the chemical examination to tumour sample, uses the sampling tube to prick into tumour sample usually in the laboratory at present to take out intraductal tumour sample, thereby study it, but when taking out, because tumour sample in the sampling tube probably does not thoroughly separate with former sample, and the inner wall of sampling tube is comparatively smooth, thereby makes tumour sample can follow the sampling tube and is taken out.
Disclosure of Invention
The present invention is directed to solving the above problems and providing a tumor sampling device that facilitates tumor separation.
The invention realizes the purpose through the following technical scheme:
a tumor sampling device convenient for tumor separation comprises a supporting mechanism, wherein a fixing mechanism used for clamping and fixing a tumor sample and a sampling mechanism arranged on the inner side of the supporting mechanism and used for sampling the tumor sample are arranged on the lower side of the supporting mechanism, and the sampling mechanism and the fixing mechanism are connected with the supporting mechanism;
the supporting mechanism comprises a handheld barrel, a supporting ring is arranged at the lower end of the handheld barrel and is in a ring shape, an annular wall is arranged at the lower end of the inner side of the supporting ring, through grooves are uniformly distributed on the upper end surface of the supporting ring, a slide way is arranged on the side wall of the handheld barrel, and a barrel cover is arranged at the upper end of the handheld barrel;
the fixing mechanism comprises a screw rod arranged at the lower end of the support ring, one end of the screw rod, which is close to the center of the support ring, is provided with a first gear, the screw rod is connected with a clamping arm, the lower end of the support ring is connected with a fluted disc, the outer wall side of the fluted disc is provided with a transmission gear, and the transmission gear is connected with a servo motor;
sampling mechanism is including passing the pressure disk of handheld section of thick bamboo, be provided with spacing boss on the pressure disk upside outer wall, the sampler barrel is worn to be equipped with by the pressure disk inboard, the sampler barrel outer lane is located pressure disk upside cover is equipped with the spring, the spring upside is located be provided with the flange on the sampler barrel outer wall, the sampler barrel upper end is provided with the clamp plate, the inside fixed plate that is provided with of sampler barrel, the fixed plate upper end is provided with the motor, the motor output is connected with the rotary cutter, on the sampler barrel outer wall with the rotary cutter corresponds the position and has seted up the opening window.
Further setting: the handheld cylinder is welded with the support ring, the two sides of the slide way are correspondingly arranged, and the through groove is provided with four positions.
Further setting: the screw rod with the support ring rotates to be connected, first gear with the screw rod welding, centre gripping arm upper end passes logical groove.
Further setting: the fluted disc with the support ring rotates to be connected, fluted disc outer wall and up end all are provided with the tooth, the fluted disc with first gear the transmission gear meshing rotates.
Further setting: the pressure plate is connected with the handheld barrel in a sliding mode, and the two sides of the limiting boss are symmetrically arranged.
Further setting: the spring with sampling tube sliding connection, the spring external diameter is greater than the pressure disk internal diameter.
Further setting: the flange with sampler barrel integrated into one piece, the flange with handheld section of thick bamboo sliding connection.
Further setting: and the rotary cutter is provided with a cutting window, and the cutting window is smaller than the opening window.
Compared with the prior art, the invention has the following beneficial effects:
carry out the centre gripping through fixed establishment to tumor sample and fix, then cut the appearance to the tumor sample that gets into in the sampling tube through the rotary cutter of sampling mechanism, make the sample be in and take out after shifting out in the confined space, avoid the sample to drop when shifting out, improved the operation of taking a sample.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic diagram of a first embodiment of a tumor sampling device for facilitating tumor isolation according to the present invention;
FIG. 2 is a schematic diagram of a second structure of a tumor sampling apparatus for conveniently separating tumors according to the present invention;
FIG. 3 is a schematic diagram of a main sectional structure of a tumor sampling device for conveniently separating tumors according to the present invention;
FIG. 4 is a partial structural view of a fixing mechanism of a tumor sampling device for conveniently separating tumors according to the present invention;
FIG. 5 is an enlarged schematic view of the structure at A in FIG. 3;
FIG. 6 is a schematic view of a split structure of a sampling mechanism of a tumor sampling device for conveniently separating tumors according to the present invention;
fig. 7 is a partial structural view of a rotary cutter of a tumor sampling device for conveniently separating tumors according to the present invention.
The reference numerals are explained below:
1. a support mechanism; 11. a hand-held cartridge; 12. a support ring; 13. a through groove; 14. a slideway; 15. a cylinder cover; 2. a fixing mechanism; 21. a screw; 22. a first gear; 23. a clamp arm; 24. a transfer gear; 25. a servo motor; 26. a fluted disc; 3. a sampling mechanism; 31. a platen; 32. a limiting boss; 33. a sampling tube; 34. an opening window; 35. a spring; 36. a flange; 37. pressing a plate; 38. a rotary cutter; 39. an electric motor; 310. and (5) fixing the plate.
Detailed Description
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The invention will be further described with reference to the accompanying drawings in which:
as shown in fig. 1-7, a tumor sampling device convenient for tumor separation comprises a supporting mechanism 1, a fixing mechanism 2 for clamping and fixing a tumor sample is arranged at the lower side of the supporting mechanism 1, and a sampling mechanism 3 for sampling the tumor sample is arranged at the inner side of the supporting mechanism 1, wherein the sampling mechanism 3 and the fixing mechanism 2 are connected with the supporting mechanism 1;
in this embodiment: the supporting mechanism 1 comprises a handheld barrel 11, the lower end of the handheld barrel 11 is welded with a supporting ring 12, the supporting ring 12 is in a ring shape, the lower end of the inner side of the supporting ring 12 is provided with a ring-shaped wall, the upper end surface of the supporting ring 12 is uniformly provided with four through grooves 13, the side wall of the handheld barrel 11 is correspondingly provided with a slide way 14, and the upper end of the handheld barrel 11 is provided with a barrel cover 15;
in this embodiment: the fixing mechanism 2 comprises a screw rod 21 rotatably installed at the lower end of the support ring 12, one end, close to the center of the support ring 12, of the screw rod 21 is welded with a first gear 22, the screw rod 21 is in threaded connection with a clamping arm 23, the upper end of the clamping arm 23 penetrates through the through groove 13, the lower end of the support ring 12 is rotatably connected with a fluted disc 26, teeth are arranged on the outer wall and the upper end face of the fluted disc 26, a transmission gear 24 is arranged on the outer wall side of the fluted disc 26, the fluted disc 26 is meshed with the first gear 22 and the transmission gear 24 to rotate, and the transmission gear 24 is connected with a servo motor 25 and used for providing power for the rotation of the fluted disc 26;
in this embodiment: sampling mechanism 3 is including sliding the pressure disk 31 that passes handheld section of thick bamboo 11, bilateral symmetry is provided with spacing boss 32 on the outer wall of pressure disk 31 upside, sample tube 33 is worn to be equipped with in pressure disk 31 inboard, the sample tube 33 outer lane is located pressure disk 31 upside cover and is equipped with spring 35, spring 35 upside is located integrated into one piece on the outer wall of sample tube 33, flange 36 and handheld section of thick bamboo 11 sliding connection, sample tube 33 upper end is provided with clamp plate 37, the inside fixed plate 310 that is provided with of sample tube 33, fixed plate 310 upper end is provided with motor 39, motor 39 output is connected with rotary cutter 38, open window 34 has been seted up with rotary cutter 38 corresponding position on the outer wall of sample tube 33, the last cutting window that has seted up of rotary cutter 38, this cutting window is less than open window 34.
The working principle and the using process of the invention are as follows: the servo motor 25 of the fixing mechanism 2 works to drive the transmission gear 24 to rotate, the fluted disc 26 drives the first gear 22 to rotate, the screw rod 21 is driven to rotate, the clamping arm 23 moves towards the middle position to clamp the tumor sample, then the pressing plate 37 of the sampling mechanism 3 presses downwards, the spring 35 pushes the lower end of the pressing plate 31 to press and hold the upper end of the tumor sample until the position is fixed, the sampling cylinder 33 continues to move downwards, the opening window 34 of the sampling cylinder 33 is partially inserted into the tumor sample, the rotary cutter 38 is driven by the motor 39 to work, the sample of the tumor sample entering the inner wall of the sampling cylinder 33 is cut off, then the reverse operation is carried out, the whole body is separated from the tumor sample, the sampling cylinder 33 is pressed out of the pressing plate 31, the rotary cutter 38 is rotated, and the cut sample is taken out through the opening window 34.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.

Claims (8)

1. A tumor sampling device for facilitating tumor separation, comprising: the tumor sample sampling device comprises a supporting mechanism (1), wherein a fixing mechanism (2) for clamping and fixing a tumor sample and a sampling mechanism (3) arranged on the inner side of the supporting mechanism (1) and used for sampling the tumor sample are arranged on the lower side of the supporting mechanism (1), and the sampling mechanism (3) and the fixing mechanism (2) are connected with the supporting mechanism (1);
the supporting mechanism (1) comprises a handheld barrel (11), a supporting ring (12) is arranged at the lower end of the handheld barrel (11), the supporting ring (12) is annular, an annular wall is arranged at the lower end of the inner side of the supporting ring (12), through grooves (13) are uniformly distributed on the upper end face of the supporting ring (12), a slide way (14) is arranged on the side wall of the handheld barrel (11), and a barrel cover (15) is arranged at the upper end of the handheld barrel (11);
the fixing mechanism (2) comprises a screw rod (21) installed at the lower end of the support ring (12), one end, close to the center of the support ring (12), of the screw rod (21) is provided with a first gear (22), the screw rod (21) is connected with a clamping arm (23), the lower end of the support ring (12) is connected with a fluted disc (26), the outer wall side of the fluted disc (26) is provided with a transmission gear (24), and the transmission gear (24) is connected with a servo motor (25);
sampling mechanism (3) is including passing pressure disk (31) of handheld section of thick bamboo (11), be provided with spacing boss (32) on pressure disk (31) upside outer wall, sampler barrel (33) are worn to be equipped with in pressure disk (31) inboard, sampler barrel (33) outer lane is located pressure disk (31) upside cover is equipped with spring (35), spring (35) upside is located be provided with flange (36) on sampler barrel (33) outer wall, sampler barrel (33) upper end is provided with clamp plate (37), sampler barrel (33) inside is provided with fixed plate (310), fixed plate (310) upper end is provided with motor (39), motor (39) output is connected with rotary cutter (38), on sampler barrel (33) outer wall with rotary cutter (38) correspond the position and seted up opening window (34).
2. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: the handheld barrel (11) is welded with the support ring (12), two sides of the slide way (14) are correspondingly arranged, and the through groove (13) is provided with four positions.
3. A tumor sampling device for facilitating tumor isolation according to claim 2, wherein: the screw rod (21) is rotationally connected with the support ring (12), the first gear (22) is welded with the screw rod (21), and the upper end of the clamping arm (23) penetrates through the through groove (13).
4. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: fluted disc (26) with support ring (12) swivelling joint, fluted disc (26) outer wall and up end all are provided with the tooth, fluted disc (26) with first gear (22), transmission gear (24) meshing rotation.
5. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: pressure disk (31) with handheld section of thick bamboo (11) sliding connection, spacing boss (32) bilateral symmetry sets up.
6. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: spring (35) with sampling tube (33) sliding connection, spring (35) external diameter is greater than pressure disk (31) internal diameter.
7. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: the flange (36) and the sampling tube (33) are integrally formed, and the flange (36) is connected with the handheld tube (11) in a sliding mode.
8. A tumor sampling device for facilitating tumor isolation according to claim 1, wherein: and a cutting window is arranged on the rotary cutter (38), and the cutting window is smaller than the opening window (34).
CN202210639813.XA 2022-06-08 2022-06-08 Tumor sampling device convenient for tumor separation Withdrawn CN115165430A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210639813.XA CN115165430A (en) 2022-06-08 2022-06-08 Tumor sampling device convenient for tumor separation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210639813.XA CN115165430A (en) 2022-06-08 2022-06-08 Tumor sampling device convenient for tumor separation

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CN115165430A true CN115165430A (en) 2022-10-11

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CN202210639813.XA Withdrawn CN115165430A (en) 2022-06-08 2022-06-08 Tumor sampling device convenient for tumor separation

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115670536A (en) * 2023-01-03 2023-02-03 潍坊医学院附属医院 Tumor detection sampling device and method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115670536A (en) * 2023-01-03 2023-02-03 潍坊医学院附属医院 Tumor detection sampling device and method

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Application publication date: 20221011