CN115155689B - Solid phase extraction module - Google Patents
Solid phase extraction module Download PDFInfo
- Publication number
- CN115155689B CN115155689B CN202210782016.7A CN202210782016A CN115155689B CN 115155689 B CN115155689 B CN 115155689B CN 202210782016 A CN202210782016 A CN 202210782016A CN 115155689 B CN115155689 B CN 115155689B
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- CN
- China
- Prior art keywords
- extraction column
- sealing plug
- test tube
- rack
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000002414 normal-phase solid-phase extraction Methods 0.000 title claims abstract description 26
- 238000000605 extraction Methods 0.000 claims abstract description 111
- 239000007788 liquid Substances 0.000 claims abstract description 50
- 238000007789 sealing Methods 0.000 claims abstract description 49
- 239000002699 waste material Substances 0.000 claims description 14
- 230000007704 transition Effects 0.000 claims description 4
- 230000007423 decrease Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 9
- 239000000945 filler Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/20—Recycling
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a solid-phase extraction module, which comprises a main frame, wherein a test tube rack is arranged on the main frame in a sliding way back and forth for longitudinally inserting test tubes; the extraction column frame is longitudinally arranged on the main frame in a sliding way and is used for longitudinally inserting the extraction column; the sealing plug fixing frame is positioned above the extraction column frames, a sealing plug is arranged on the sealing plug fixing frame corresponding to each extraction column, and the sealing plugs are provided with liquid adding openings for adding liquid to the extraction columns; the top surface of the guide rail is provided with an upper convex section and a lower concave section, the test tube rack is connected with the upper convex section to drive the guide rail to move back and forth, the extraction column rack falls on the guide rail so as to drive each extraction column to rise when being supported by the upper convex section, each sealing plug on the upper sealing plug fixing frame is used for sealing and adding liquid, each test tube on the test tube rack is moved to the lower part of each extraction column to receive the extraction liquid, and the extraction column rack is enabled to drive each extraction column to fall when being supported by the lower concave section and separate from each sealing plug. The invention can drive the sample pipe rack and the extraction column rack to move respectively through one driving mechanism, thus completing solid phase extraction.
Description
Technical Field
The invention relates to the technical field of solid phase extraction devices, in particular to a solid phase extraction module.
Background
Solid phase extraction is a sample pretreatment technology developed in recent years, extraction columns, sample liquid filling devices and sample tubes are usually arranged on solid phase extraction equipment, liquid filling ports are arranged at the top ends of the extraction columns, liquid discharge ports are arranged at the bottom ends of the extraction columns, fillers are arranged in the extraction columns, sample liquid is filled into the extraction columns from the liquid filling ports through the sample liquid filling devices, the sample liquid is subjected to solid phase extraction through the fillers, then extraction liquid is formed, the extraction liquid is discharged through the liquid discharge ports, and the sample tubes are arranged below the liquid discharge ports to receive the extraction liquid.
In the solid phase extraction process, the extraction column and the sample tube need to be frequently installed and removed, the extraction column is usually inserted on the extraction column frame, the sample tube is inserted on the sample tube frame, and a driving mechanism is arranged to drive the extraction column frame to horizontally move to the position above the sample tube frame for column passing or to move away from the position above the sample tube frame, so that the sample tube can be conveniently taken and placed; and meanwhile, the other driving mechanism is arranged to drive the extraction column frame to ascend, so that the liquid filling opening of the extraction column is propped against the sample liquid filling device to fill liquid, or the liquid is separated from the sample liquid filling device in a descending manner, so that the extraction column can be conveniently taken and placed.
If the sample pipe rack and the extraction column rack can be driven to move respectively by one driving mechanism, the solid phase extraction process is completed, and the cost of the solid phase extraction equipment is reduced.
Disclosure of Invention
The invention aims to provide a solid phase extraction module, which overcomes the defects, and the sample pipe rack and the extraction column rack are driven to move respectively by a driving mechanism to complete the solid phase extraction process.
To achieve the above object, the solution of the present invention is: a solid phase extraction module comprises a main frame, a test tube rack, an extraction column rack, a sealing plug fixing rack and a guide rail;
the test tube rack is arranged on the main frame in a sliding way back and forth and is used for longitudinally inserting at least one test tube;
the extraction column frame is longitudinally arranged on the main frame in a sliding manner and is used for longitudinally inserting at least one extraction column;
the sealing plug fixing frame is positioned above the extraction column frame, a sealing plug is arranged on the sealing plug fixing frame corresponding to each extraction column, and a liquid adding port for adding liquid to the extraction column is arranged on the sealing plug fixing frame;
the guide rail top surface sets gradually and smooth transition is formed with protruding section, concave section from beginning to end, the test-tube rack is connected protruding section, drives go up the guide rail back and forth movement, the extraction column frame falls on the guide rail, in order to receive when going up protruding section bearing, drive each extraction column and rise, go up to each sealing plug on the sealing plug mount seals the liquid feeding, and supplies each test tube on the test-tube rack removes to each extraction column below and accepts the extract, receive when concave section bearing, makes the extraction column frame drive each extraction column decline, separates with each sealing plug.
Further, the sealing plug fixing frame is connected to the main frame in a front-back sliding manner so as to move to or away from the position right above each extraction column.
Further, the sealing plug fixing frame is connected with a second linear driving mechanism, and the second linear driving mechanism drives the sealing plug fixing frame to slide forwards and backwards.
Further, the front side or the rear side of the test tube rack is provided with a waste liquid tank which slides back and forth along with the test tube rack so as to receive waste liquid discharged by the extraction column when moving to the lower side of the extraction column.
Further, the waste liquid tank is located at the upper convex section.
Further, an elastic piece is connected between the extraction column frame and the main frame, and pushes down the extraction column frame.
Further, a roller is arranged on the extraction column frame, and the roller falls on the guide rail to roll.
Further, the test tube rack is connected with a first linear driving mechanism, and the first linear driving mechanism drives the test tube rack to slide back and forth.
After the scheme is adopted, the beneficial effects of the invention are as follows: the test tube rack slides back and forth and sets up on the body frame, extraction column rack longitudinal sliding sets up on the body frame, the sealing plug mount is located extraction column rack top, the guide rail top sets gradually around and smooth transition is formed with protruding section, concave section down, the test tube rack is connected go up protruding section, drive at test tube rack gliding in-process back and forth the guide rail reciprocates, extraction column rack falls on the guide rail, when the test tube rack moves to extraction column rack below and makes the test tube accept extraction column exhaust extract, goes up protruding section and moves to extraction column rack below simultaneously, makes extraction column rack receive protruding section bearing, drives each extraction column and rises to support each sealing plug on the sealing plug mount carries out sealed liquid feeding this moment, and when the test tube rack shifts out extraction column rack below, makes extraction column rack receive concave section down, drives each extraction column to descend, separates with each sealing plug, can conveniently get and put and extract column support test tube rack this moment, and whole in the motion only need drive mechanism can accomplish whole motion in the whole process.
Drawings
FIG. 1 is a schematic perspective view of an extraction column of the present invention supported by a concave section of a guide rail;
FIG. 2 is a schematic view showing a perspective structure of an extraction column of the present invention in another direction when supported by a concave section of a guide rail;
FIG. 3 is a schematic perspective view of the extraction column of the present invention when supported by the upper protruding section of the guide rail for solid phase extraction;
fig. 4 is a schematic perspective view of the sealing plug holder of the present invention when it is removed from the extraction column.
Description of the reference numerals: the device comprises a main frame, a 2-test tube rack, a 3-extraction column rack, a 4-sealing plug fixing frame, a 5-guide rail, a 6-test tube, a 7-extraction column, an 8-sealing plug, a 9-liquid adding port, a 10-upper convex section, a 11-lower concave section, a 12-second linear driving mechanism, a 13-waste liquid groove, a 14-elastic piece, a 15-roller, a 16-first linear driving mechanism, a 17-tray, a 18-first linear guide rail pair, a 19-portal frame, a 20-guide rod, a 21-second linear guide rail pair, a 22-support rod, a 23-first motor, a 24-first lead screw nut pair, a 25-second motor and a 26-second lead screw nut pair.
Detailed Description
The invention will be described in detail with reference to the accompanying drawings and specific embodiments.
The invention provides a solid-phase extraction module, as shown in figures 1-4, which is mainly shown in figure 1, and comprises a main frame 1, a test tube rack 2, an extraction column frame 3, a sealing plug fixing frame 4 and a guide rail 5;
the test tube rack 2 is slidably disposed on the main frame 1 back and forth for at least one test tube 6 to be inserted longitudinally, and in this embodiment, the main frame 1 includes a tray 17, a first linear guide rail pair 18 extending back and forth is mounted on the upper surface of the tray 17, and the test tube rack 2 is slidably connected to the tray 17 back and forth through the first linear guide rail pair 18;
the extraction column frame 3 is longitudinally slidably disposed on the main frame 1 for longitudinally inserting at least one extraction column 7, in this embodiment, the main frame 1 further includes a gantry 19, the gantry 19 is symmetrically fixed above the tray 17, the test tube rack 2 passes through the gantry 19 in the process of sliding back and forth, two longitudinally extending guide rods 20 are respectively disposed on the left and right sides of the gantry 19, and the left and right sides of the extraction column frame 3 are respectively sleeved on one guide rod 20 so as to longitudinally slide under the guide of the guide rods 20;
the sealing plug fixing frame 4 is located above the extraction column frame 3 and is installed at the top of the portal 19, a sealing plug 8 is arranged on the sealing plug fixing frame 4 corresponding to each extraction column 7, the sealing plugs 8 are provided with liquid adding openings 9 for adding liquid to the extraction columns 7, and the liquid adding openings 9 are communicated with liquid feeding devices such as liquid adding pumps, and the liquid feeding devices are not shown in the drawings in the prior art;
the guide rail 5 bilateral symmetry is provided with two, two guide rail 5 is fixed respectively the left and right sides of test-tube rack 2, the guide rail 5 top front and back sets gradually and smooth transition is formed with protruding section 10, concave section 11 down, test-tube rack 2 connects the position that the protruding section 10 of guide rail 5 is located, drives guide rail 5 back and forth movement, extraction column rack 3 left and right sides downwardly extending respectively has a branch 22, two branch 22 bottom falls respectively on two on the guide rail 5, in the in-process that guide rail 5 moved along with test-tube rack 2 back and forth, the key combines the drawing of figure 3, and when test-tube rack 2 slides to extraction column rack 3 below, simultaneously drive protruding section 10 of guide rail 5 slides to branch 22 below, extraction column rack 3 receives protruding section 10 bearing, drives each extraction column 7 to rise, supports each sealing plug 8 on mount 4 to carry out the sealing plug 8 to supply on extraction column rack 2, and the key combines the drawing of figure 1 bottom to fall on extraction column 7, and the concave section 3 has enough to draw down in the support column rack 3 when the recess section 3, and the support column rack 3 has enough to draw down, and the extraction column 11 has the height to make the extraction column 3 to draw down, and the support column 11 has the height to draw down, and the extraction column 3 has enough to draw down the extraction column 11.
The structure of the driving mechanism for driving the test tube rack 2 to slide back and forth is not particularly limited, in this embodiment, as shown in fig. 2, the test tube rack 2 is connected with a first linear driving mechanism 16, the first linear driving mechanism 16 is mounted on the tray 17, and includes a first motor 23 and a first screw nut pair 24, and the first motor 23 drives the first screw nut pair 24 to drive the test tube rack 2 to move back and forth.
In particular, in this embodiment, a second linear guide pair 21 is installed at the top end of the door frame 19, the second linear guide pair 21 extends back and forth, the sealing plug fixing frame 4 is connected to the top of the door frame 19 through the second linear guide pair 21, the second linear driving mechanism 12 is connected to the sealing plug fixing frame 4, the second linear driving mechanism 12 is installed on the door frame 19, the second motor 25 and the second screw nut pair 26 are included, the second motor 25 drives the second screw nut pair 26 to drive the sealing plug fixing frame 4 to slide back and forth so as to move to or move away from right above each extraction column 7, and after each extraction column 7 is moved away, the upper part of each extraction column 7 is free from shielding, so that the extraction column 7 is more convenient to take out.
With particular reference to fig. 1, in order to collect the waste liquid discharged from the extraction column 7 during the solid phase extraction, a waste liquid tank 13 is disposed at the front side or the rear side of the test tube rack 2, in this embodiment, the waste liquid tank 13 is disposed at the rear side of the test tube rack 2, the waste liquid tank 13 slides back and forth along with the test tube rack 2, and the waste liquid tank 13 is disposed at the upper convex section 10 of the guide rail 5 to receive the waste liquid discharged from the extraction column 7 when moving to the lower side of the extraction column 7.
As shown in fig. 1, the extraction column frame 3 falls freely under gravity in the falling process, so as to avoid the clamping of the falling process of the extraction column frame 3, so that the falling of the extraction column frame 3 is smoother, an elastic member 14 is connected between the extraction column frame 3 and the main frame 1, the elastic member 14 pushes down the extraction column frame 3, and in this embodiment, the elastic member 14 is a spring, and two elastic members are respectively sleeved on the two guide rods 20.
In order to reduce friction resistance, the extraction column frame 3 is provided with two rollers 15, specifically in this embodiment, the two rollers 15 are provided, and are respectively installed at the bottom ends of two supporting rods 22 extending downwards from the extraction column frame 3, and the rollers 15 fall on the guide rail 5 to roll.
The above embodiments are only preferred embodiments of the present invention, and are not limited to the present invention, and all equivalent changes made according to the design key of the present invention fall within the protection scope of the present invention.
Claims (8)
1. A solid phase extraction module, characterized by: comprises a main frame (1), a test tube rack (2), an extraction column rack (3), a sealing plug fixing rack (4) and a guide rail (5);
the test tube rack (2) is arranged on the main frame (1) in a front-back sliding way and is used for longitudinally inserting at least one test tube (6);
the extraction column frame (3) is longitudinally arranged on the main frame (1) in a sliding manner and is used for longitudinally inserting at least one extraction column (7);
the sealing plug fixing frame (4) is positioned above the extraction column frame (3), a sealing plug (8) is arranged on the sealing plug fixing frame (4) corresponding to each extraction column (7), and a liquid adding opening (9) for adding liquid to the extraction columns (7) is arranged on the sealing plug (8);
the utility model discloses a test tube rack, including guide rail (5), test tube rack, extraction column rack (3), sealed liquid feeding is carried out to each sealing plug (8) on sealing plug mount (4) on guide rail (5) top front and back sets gradually and smooth transition is formed with protruding section (10), concave section (11), test tube rack (2) are connected protruding section (10) are gone up, drive guide rail (5) back and forth movement, extraction column rack (3) are in on guide rail (5), in order to receive when protruding section (10) bearing goes up, go up each sealing plug (8) on sealing plug mount (4) carries out sealed liquid feeding, and supplies each test tube (6) on test tube rack (2) move to each extraction column (7) below and accept the extract, receive when concave section (11) bearing makes extraction column rack (3) drive each extraction column (7) decline, separate with each sealing plug (8).
2. A solid phase extraction module as claimed in claim 1, wherein: the sealing plug fixing frame (4) is connected to the main frame (1) in a front-back sliding way so as to move to or away from the position right above each extraction column (7).
3. A solid phase extraction module as claimed in claim 2, wherein: the sealing plug fixing frame (4) is connected with a second linear driving mechanism (12), and the second linear driving mechanism (12) drives the sealing plug fixing frame (4) to slide forwards and backwards.
4. A solid phase extraction module as claimed in claim 1, wherein: the front side or the rear side of the test tube rack (2) is provided with a waste liquid groove (13), and the waste liquid groove (13) slides back and forth along with the test tube rack (2) so as to receive waste liquid discharged by the extraction column (7) when moving to the lower part of the extraction column (7).
5. A solid phase extraction module as claimed in claim 4, wherein: the waste liquid tank (13) is positioned at the upper convex section (10) of the guide rail (5).
6. A solid phase extraction module as claimed in claim 1, wherein: an elastic piece (14) is connected between the extraction column frame (3) and the main frame (1), and the elastic piece (14) pushes down the extraction column frame (3).
7. A solid phase extraction module as claimed in claim 1, wherein: the extraction column frame (3) is provided with a roller (15), and the roller (15) falls on the guide rail (5) to roll.
8. A solid phase extraction module as claimed in claim 1, wherein: the test tube rack (2) is connected with a first linear driving mechanism (16), and the first linear driving mechanism (16) drives the test tube rack (2) to slide back and forth.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202210782016.7A CN115155689B (en) | 2022-07-05 | 2022-07-05 | Solid phase extraction module |
Applications Claiming Priority (1)
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CN202210782016.7A CN115155689B (en) | 2022-07-05 | 2022-07-05 | Solid phase extraction module |
Publications (2)
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CN115155689A CN115155689A (en) | 2022-10-11 |
CN115155689B true CN115155689B (en) | 2024-03-26 |
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CN202210782016.7A Active CN115155689B (en) | 2022-07-05 | 2022-07-05 | Solid phase extraction module |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB184826A (en) * | 1921-03-18 | 1922-08-18 | Ernest Edward Glynn | Improvements in delivering predetermined volumes of liquid |
KR100817536B1 (en) * | 2007-10-31 | 2008-03-27 | (주)제네마인 | A high performance extractor as possible with ascending and descending extraction |
EP2148206A1 (en) * | 2008-07-25 | 2010-01-27 | F.Hoffmann-La Roche Ag | A laboratory system for handling sample tube racks, an alignmemt element for sample tube racks and a rack tray receiver assembly |
CN202018398U (en) * | 2010-11-26 | 2011-10-26 | 北京莱伯泰科仪器有限公司 | Full-automatic solid phase extraction device with automatic column switching function |
CN203598534U (en) * | 2013-11-22 | 2014-05-21 | 田靖 | Solid-phase extraction device |
CN107505186A (en) * | 2017-10-13 | 2017-12-22 | 苏州市苏测检测技术有限公司 | New solid-phase extracting instrument |
CN214319205U (en) * | 2020-11-05 | 2021-10-01 | 四川凯乐检测技术有限公司 | Solid phase extraction appearance convenient to adjust gas flow |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015109219A2 (en) * | 2014-01-17 | 2015-07-23 | Hamilton Company | Automated positive pressure solid phase extraction apparatus and method |
-
2022
- 2022-07-05 CN CN202210782016.7A patent/CN115155689B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB184826A (en) * | 1921-03-18 | 1922-08-18 | Ernest Edward Glynn | Improvements in delivering predetermined volumes of liquid |
KR100817536B1 (en) * | 2007-10-31 | 2008-03-27 | (주)제네마인 | A high performance extractor as possible with ascending and descending extraction |
EP2148206A1 (en) * | 2008-07-25 | 2010-01-27 | F.Hoffmann-La Roche Ag | A laboratory system for handling sample tube racks, an alignmemt element for sample tube racks and a rack tray receiver assembly |
CN202018398U (en) * | 2010-11-26 | 2011-10-26 | 北京莱伯泰科仪器有限公司 | Full-automatic solid phase extraction device with automatic column switching function |
CN203598534U (en) * | 2013-11-22 | 2014-05-21 | 田靖 | Solid-phase extraction device |
CN107505186A (en) * | 2017-10-13 | 2017-12-22 | 苏州市苏测检测技术有限公司 | New solid-phase extracting instrument |
CN214319205U (en) * | 2020-11-05 | 2021-10-01 | 四川凯乐检测技术有限公司 | Solid phase extraction appearance convenient to adjust gas flow |
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CN115155689A (en) | 2022-10-11 |
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