CN115154537B - Traditional Chinese medicine composition for treating lumbar disc herniation and application thereof - Google Patents
Traditional Chinese medicine composition for treating lumbar disc herniation and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lumbar disc herniation and application thereof, and belongs to the technical field of traditional Chinese medicines. The preparation method comprises the following raw materials in parts by weight: 5-10 parts of nutgrass galingale rhizome, 5-10 parts of corydalis tuber, 5-10 parts of divaricate saposhnikovia root, 5-10 parts of Chinese angelica, 5-10 parts of red paeony root, 1-10 parts of szechuan lovage rhizome, 5-10 parts of pubescent angelica root, 5-10 parts of salt malaytea scurfpea fruit, 5-10 parts of stir-fried ground beetle, 5-10 parts of himalayan teasel root, 5-15 parts of prepared rhizoma cibotii, 5-10 parts of salt stir-fried achyranthes root, 5-15 parts of mistletoe, 1-10 parts of prepared myrrh and 1-10 parts of stir-fried liquorice. The traditional Chinese medicine composition has the effects of promoting qi circulation, removing blood stasis, tonifying kidney and dredging collaterals, and clinical experiments show that the traditional Chinese medicine composition can obviously improve the traditional Chinese medicine clinical symptoms of patients with lumbar disc herniation caused by qi stagnation and blood stasis, and has higher clinical application value in the aspect of treating lumbar disc herniation.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating lumbar disc herniation and application thereof.
Background
Lumbar disc herniation is a disease in which lumbar disc degeneration, rupture of annulus fibrosus, herniation of nucleus pulposus, compression and stimulation of nerve roots, cauda equina nerves or spinal cord at corresponding levels cause lumbago and lower limb radiation pain as main symptoms, and is a common orthopedic disease. With the progress of society and the popularization of computer offices, the incidence rate of the Chinese herbal medicine is in an increasing trend year by year, the Chinese herbal medicine seriously threatens the health of human beings, brings inconvenience for life and work to patients, causes a certain psychological burden and becomes a public health problem threatening the health of human beings. The traditional Chinese medicine classic works "Huangdi's internal channel" has related knowledge in ancient times in China as early as lumbago, and makes detailed discussion on the etiology, pathogenesis and clinical manifestations of the disease, and proposes that "the waist is the house of the kidney, the transformation and shaking cannot be done, the kidney is tired, the wind-cold-dampness is mixed with three qi and is arthralgia" and other famous remarks, the occurrence of the disease is considered to be mainly caused by congenital kidney qi deficiency, acquired kidney qi deficiency, repeated trauma, chronic strain and wind-cold-dampness pathogen invasion, and the main pathogenesis is as follows: the main symptoms of the pain caused by the obstruction of kidney qi, pathogenic factors blocking the channels and collaterals, incoordination between nutrient and defensive qi, qi stagnation and blood stasis, and obstruction of the tendons and vessels of the waist and legs are pain at the waist and leg parts.
The Chinese medicine diagnosis and treatment standards such as the "Chinese medicine clinical diagnosis and treatment terminology and the" Chinese medicine disease diagnosis and treatment effect standard "are specific description of the Chinese medicine differentiation type of the lumbar disc herniation, and are divided into four types of qi stagnation and blood stasis syndrome, cold-dampness obstruction syndrome, damp-heat obstruction syndrome and liver and kidney deficiency syndrome. Qi stagnation and blood stasis type lumbago is common in clinic, and is mainly characterized by sustained waist strength, or long-term body position misalignment, or waist strength misalignment, traumatic injury, strain on the tendons and vessels, qi and blood unsmooth circulation, waist qi stagnation, blood stasis and lumbago, fixed pain in the waist, or discomfort of distending pain, pain such as cone puncture, light day and heavy night, unfavorable activity, even failure to turn the side, pain rejection in the pain part, which is the main characteristic of the syndrome, to activate blood circulation to remove blood stasis, regulate qi and alleviate pain. At present, a plurality of traditional Chinese medicine formulas for treating lumbar disc herniation are based on promoting blood circulation and promoting qi circulation, relieving swelling and pain, and are supplemented with medicinal materials for tonifying liver and kidney to achieve the effect of treating the principal and secondary aspect of disease, wherein the traditional Chinese medicine formulas mainly comprise medicinal materials such as radix angelicae pubescentis, large-leaf gentian, red paeony root, safflower, wild pepper, dried ginger, mugwort leaf, diverse wormwood herb, schizonepeta herb, divaricate saposhnikovia root, prepared common monkshood mother root, aconite root, cortex acanthopanacis, radix aconiti, papaya, garden balsam stem, lycopodium clavatum, mulberry twig, rheum officinale and the like, wherein the medicinal materials such as radix angelicae pubescentis, red paeony root, safflower, mugwort leaf and the like have good effects of promoting blood circulation and removing blood stasis; while the medicinal materials such as schizonepeta, divaricate saposhnikovia root, gentiana macrophylla, chinese prickly ash, dried ginger and the like can dispel wind and cold, dry dampness and resolve phlegm; the prepared common monkshood mother root, aconite root and other medicinal materials can effectively reduce swelling and relieve pain; the medicinal materials such as Sichuan radix, papaya, garden balsam stem, lycopodium clavatum, mulberry twig and the like can relax tendons and activate collaterals, so that tendons and vessels are nourished; herba Visci, radix Achyranthis bidentatae, rhizoma Cibotii preparata, and fructus Psoraleae can tonify liver and kidney, strengthen tendons and bones, and can be modified according to symptoms of patients in clinical treatment. Although the medicine can be used for treating lumbago, the curative effect in clinical practice is not definite, and it is necessary to dig a new Chinese medicinal prescription from the abundant Chinese medicinal treasures.
Disclosure of Invention
The invention mainly aims to provide a traditional Chinese medicine composition for treating lumbar disc herniation, which is prepared from the following raw materials in parts by weight: 5-10 parts of nutgrass galingale rhizome, 5-10 parts of corydalis tuber, 5-10 parts of divaricate saposhnikovia root, 5-10 parts of Chinese angelica, 5-10 parts of red paeony root, 1-10 parts of szechuan lovage rhizome, 5-10 parts of pubescent angelica root, 5-10 parts of salt malaytea scurfpea fruit, 5-10 parts of stir-fried ground beetle, 5-10 parts of himalayan teasel root, 5-15 parts of prepared rhizoma cibotii, 5-10 parts of salt stir-fried achyranthes root, 5-15 parts of mistletoe, 1-10 parts of prepared myrrh and 1-10 parts of stir-fried liquorice.
Preferably, the traditional Chinese medicine composition for treating the lumbar disc herniation is prepared from the following raw materials in parts by weight: 9 parts of nutgrass galingale rhizome, 7 parts of corydalis tuber, 7 parts of divaricate saposhnikovia root, 9 parts of Chinese angelica, 9 parts of red paeony root, 5 parts of szechuan lovage rhizome, 7 parts of pubescent angelica root, 9 parts of salted malaytea scurfpea fruit, 9 parts of stir-fried ground beetle, 9 parts of himalayan teasel root, 11 parts of prepared rhizoma cibotii, 9 parts of salted stir-fried achyranthes root, 11 parts of mistletoe, 5 parts of prepared myrrh and 5 parts of stir-fried liquorice.
The Chinese medicine has the following functions, main indications and action principles: has effects of activating qi-flowing, removing blood stasis, invigorating kidney, and dredging collaterals; wherein, the nutgrass galingale rhizome has the functions of promoting qi circulation, regulating qi-flowing, resolving depression, regulating menstruation and relieving pain; rhizoma corydalis is a monarch drug for promoting blood circulation, dispelling blood stasis, promoting qi circulation and relieving pain; the Chinese angelica, the red paeony root and the szechuan lovage rhizome have the effects of strengthening qi and removing blood stasis and are jointly used as ministerial drugs; radix sileris and radix angelicae pubescentis are used as adjuvant drugs, and fried licorice root is used as an guiding drug, and the action principle is as follows:
and (3) rhizoma cyperi: xin Weigu sweet, calm, enter liver and triple energizer meridians, ben Cao Shu (materia Medica): the nutgrass galingale rhizome is mainly used for treating various symptoms, and when the nutgrass galingale rhizome is examined as qi diseases in blood, the nutgrass galingale rhizome is of Zhengjin just, and is different from the smell of all therapeutic gases, and the nutgrass galingale rhizome has the effects of regulating qi, resolving depression, regulating menstruation and relieving pain; rhizoma corydalis: pungent and bitter, warm, enter liver, stomach, heart, lung and spleen meridians, compendium: "activating blood, promoting qi circulation, relieving pain, promoting urination, and promoting blood circulation, qi stagnation and blood stagnation, so it is specially used for treating all pains of the body, and in use, it is not known in the art, it has the effects of removing blood stasis, promoting blood circulation, promoting qi circulation and relieving pain. The two drugs are used together as monarch drugs, and have the effects of activating blood circulation to dissipate blood stasis, promoting qi circulation and relieving pain.
Chinese angelica root: sweet, spicy, warm, enter liver, heart and spleen meridians, which can nourish blood, promote blood circulation, nourish middle energizer, and nourish middle energizer, which are essential drugs in blood; radix paeoniae rubra: bitter and slightly cold, enter liver meridian, and have the effects of clearing heat and cooling blood, and activating blood circulation to dissipate blood stasis; ligusticum wallichii: pungent and warm, liver and gallbladder meridian entered are commonly used for promoting blood circulation and qi circulation, dispelling wind and relieving pain, which are pungent, warm, fragrant and dry, can travel without being blocked, can travel and travel up to the vertex; blood flows into the body and down to the sea. The three are combined together to strengthen the effect of promoting qi circulation and removing blood stasis, and are jointly used as ministerial drugs.
Ground beetle: salty and cold, enters liver meridian, has the effects of breaking blood and removing stasis, and promoting reunion of fractured bones; teasel root: bitter and pungent, slightly warm, enter liver and kidney meridians, ben Cao in Yunnan (materia Medica): "tonify liver, strengthen tendons and bones, stop meridians and relieve soreness of middle energizer (tendons and bones)", has effects of nourishing liver and kidney, strengthening tendons and bones, and continuing to fracture; myrrh: bitter and pungent, calm, enter liver, spleen, heart and kidney meridians, have the actions of dispelling blood stasis, relieving swelling and pain; mistletoe: bitter and sweet, calm, enter liver and kidney meridians, and has the actions of tonifying liver and kidney and strengthening tendons and bones; achyranthes root: bitter sweet and sour, calm, enter liver and kidney meridians, and has the actions of removing blood stasis, dredging meridians, tonifying liver and kidney, and guiding blood down. Preparing rhizoma Cibotii: bitter and flat, with the actions of strengthening waist and back and strengthening tendons and bones; fructus psoraleae: bitter and pungent, warm, enter kidney and spleen meridians, and has the actions of tonifying kidney and strengthening yang. The medicines are used together, so that the traditional Chinese medicine has the effects of breaking blood and removing stasis, reuniting bones, tonifying liver and kidney and strengthening tendons and bones, and is taken as an adjuvant medicine.
Licorice root: sweet nature, and the spleen and stomach meridians of heart, lung, spleen and stomach, discrimination rights are: the licorice root is the monarch drug, and is used for treating seventy-two opalescent toxins, resolving one thousand of two hundred-year-old herb toxins, and harmonizing the active ingredients of many drugs, so that the drug is the guiding drug.
The invention also provides application of the traditional Chinese medicine composition for treating the lumbar disc herniation in preparation of medicines for treating the lumbar disc herniation.
Preferably, the prolapse of lumbar intervertebral disc is a pattern of qi stagnation and blood stasis.
Preferably, the mixture of the active ingredients of the traditional Chinese medicine composition after extraction is prepared into a pharmaceutically acceptable pharmaceutical preparation.
Preferably, the pharmaceutical preparation comprises the extract of the traditional Chinese medicine composition and a pharmaceutically acceptable pharmaceutical carrier or excipient, and the dosage form comprises tablets, capsules, soft capsules, granules, pills, powder, ointment, suspension or decoction.
Preferably, the pharmaceutical preparation is decoction, and is taken orally for 2 weeks, 50mL each time, half an hour after meal.
Preferably, the preparation method of the decoction comprises the following steps:
step one, mixing the raw materials according to the amount of the formula, adding water, soaking the medicinal powder for 60 minutes;
continuously adding water into the raw materials of the formula soaked in the step one, soaking the raw materials for 3-4 cm above the medicine surface, decocting with strong fire until the raw materials are boiled, continuously decocting with slow fire for 60 minutes until the residual liquid medicine is concentrated to 100mL, filtering, and taking filtrate for later use;
and thirdly, continuously adding water into the residual medicine obtained in the second step, boiling the medicine after the water is 2-3 cm above the medicine surface, decocting the medicine with strong fire for 60 minutes, filtering the medicine until the residual medicine liquid is concentrated to 100mL, and mixing the filtrate with the filtrate obtained in the second step.
The traditional Chinese medicine composition for treating the lumbar disc herniation is obtained by following the principle of dialectical treatment of traditional Chinese medicine based on the previous experience, and has the effects of promoting qi circulation, removing blood stasis, tonifying kidney and dredging collaterals proved by modern pharmacological research and long-term clinical practice.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention are clearly and completely described below. It will be apparent that the described embodiments are some, but not all, embodiments of the invention. All other embodiments, which can be made by a person skilled in the art without creative efforts, based on the described embodiments of the present invention fall within the protection scope of the present invention.
The clinical experiments prove that the traditional Chinese medicine composition provided by the invention has clinical curative effects on treating lumbar disc herniation, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 9 parts of nutgrass galingale rhizome, 7 parts of corydalis tuber, 7 parts of divaricate saposhnikovia root, 9 parts of Chinese angelica, 9 parts of red paeony root, 5 parts of szechuan lovage rhizome, 7 parts of pubescent angelica root, 9 parts of salted malaytea scurfpea fruit, 9 parts of stir-fried ground beetle, 9 parts of himalayan teasel root, 11 parts of prepared rhizoma cibotii, 9 parts of salted stir-fried achyranthes root, 11 parts of mistletoe, 5 parts of prepared myrrh and 5 parts of stir-fried liquorice.
In the following examples, the following steps are performed to patients with a traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition: soaking the medicinal materials in water for 60 min according to the formula of the traditional Chinese medicine composition; continuously adding water into the soaked formula raw materials until the water is 3-4 cm above the medicine surface, decocting with strong fire until the water is boiled, continuously decocting with slow fire for 60 minutes until the residual liquid medicine is concentrated to 100mL, filtering, and collecting filtrate for later use; adding water into the rest materials, decocting with strong fire until the powder surface is 2-3 cm, decocting with slow fire for 60 min, filtering, and concentrating the rest liquid medicine to 100mL.
Example 1
The clinical research case selection 2021 month 1 to 2021 month 12 is from patients suffering from lumbar disc herniation caused by qi stagnation and blood stasis of spinal specific diseases in seventh people hospitals in Shanghai city, meets inclusion and exclusion standards, and the patients agree to participate in the clinical observation, 30 cases are collected in total, and the traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition is applied to treatment, so that relevant indexes of traditional Chinese medicine symptoms and relevant physical sign scores are observed.
1. Diagnostic and inclusion criteria
1.1 Western medicine diagnosis Standard the following criteria were formulated with reference to the diagnosis Standard for prolapse of lumbar intervertebral disc in the "Standard for curative effect for diagnosis of Condition of Chinese medicine": (1) most patients have a history of chronic strain trauma or cold dampness; (2) frequently occurs in young and old; (3) when the abdominal pressure is increased, the lumbago is obvious, or the buttocks and lower limbs are painful with radioactivity and are tingled; (4) lumbar curvature refers to the diminished or lost waist, limited lumbar forward flexion movement; (5) the region of the affected nerve of the lower limb is provided with sensory disturbance, and muscular atrophy can be seen by patients with long-term illness; (6) the X-ray examination can show that the scoliosis, the lumbar vertebra physiological curve is straightened or vanished, the pathological change intervertebral space is narrowed, and the adjacent vertebral body edge can show bone hyperplasia; (7) CT examination can clearly determine the lesion.
1.2 diagnostic criteria for chinese medicine: referring to 92 kinds of clinical paths of traditional Chinese medicine and traditional Chinese medicine diagnosis and treatment schemes (2018 edition) of the traditional Chinese medicine management office: (1) syndrome of qi stagnation and blood stasis: pain in the waist and legs, pain in the waist, stiff lumbar plate, limited pitching rotation, depression rejection in pain parts, dark tongue with thin and white coating, wiry and tight pulse; (2) cold-dampness arthralgia syndrome: cold pain in the waist and legs is severe, the turning side is unfavorable, the pain in the rest and lying is not reduced, the pain is aggravated by cold and overcast and rain, the limbs are cool, the tongue is pale, the coating is white and greasy, and the pulse is wiry and tight; (3) syndrome of damp-heat blockage: pain in the waist, pain with heat sensation, pain increase in hot or rainy days, or red and swollen limbs, scanty and reddish urine, yellow and greasy coating and slippery and rapid pulse; (4) deficiency of liver and kidney: the pain in the waist is long in duration, repeated attacks, debilitation, intolerance, aggravated fatigue and relieved lying condition, including deficiency of liver-yin and kidney-yin and deficiency of liver-yang and kidney-yang, wherein the deficiency of yin is as follows: restlessness, insomnia, bitter taste in the mouth, dry throat, red tongue with little coating, wiry and thready pulse; the yang deficiency syndrome is as follows: the limbs are cold and aversion to cold, the tendons and vessels are contracture, the tongue is pale, the coating is thin and white, and the vessels are deep and thready.
1.3 case inclusion criteria: (1) meeting the above diagnostic criteria; (2) age 15-55 years, course of disease varies from 1 month to 18 years; (3) agreeing to participate and actively cooperate with the treatment scheme, signing an informed consent, and approving by the medical ethics committee to perform the clinical trial; (4) voluntarily as observers, and can be regularly re-diagnosed according to requirements.
1.4 case exclusion criteria: (1) combined with intraspinal or intrathecal tumors, tuberculosis, osteomyelitis, severe osteoporosis and osteopontia; (2) combining severe primary diseases such as severe barycenter cerebrovascular diseases, liver and kidney dysfunction, hematopoietic system dysfunction and the like; (3) a patient who is subjected to lumbar surgery and minimally invasive treatment; (4) pregnant and lactating women; (5) mental patients; (6) the treatment sites of the manipulation method are patients with serious skin burn, scald and defect or skin disease; (7) lumbar spinal stenosis caused by bone hyperplasia, ligament thickening or lumbar spondylolisthesis; (8) the imaging diagnosis is that the lumbar disc herniation, the lower limb muscle strength is less than or equal to grade III or the abnormal urination and defecation of the saddle area with the caudal equina compression are affected.
1.5 cases shedding and rejection criteria: (1) poor subject compliance, inability to adhere to the therapist; (2) serious adverse reactions occur, such as abnormal nerve functions; (3) other serious diseases appear in the clinical test process; (4) the treatment is effective, but the curative effect cannot be judged by adding other treatment methods.
2. Evaluation index
The treatment effect is observed after one week and two weeks, and the VAS score, ODI score and lumbar vertebra activity improvement condition of the patients on days 7 and 14 are mainly observed. Efficacy assessment: referring to the traditional Chinese medicine industry standard of the people's republic of China, namely the clinical efficacy assessment standard judgment of the traditional Chinese medicine disease diagnosis efficacy standard (ZY/T001.1-94), and the efficacy standard assessment formulated by the ODI scoring table:
efficacy index = (pre-treatment ODI score-post-treatment score)/pre-treatment score x 100%.
And (3) healing: the pain of the waist, the sacroiliac joint and the lower limb radiation pain basically disappear, the waist function is recovered to be normal, the straight leg is raised by more than 70 degrees, and the curative effect index is more than 80 percent.
The effect is shown: the pain of the waist and the pain of the lower limbs are obviously relieved, the function of the waist activity is basically normal, the activity is slightly limited, the residual waist is uncomfortable or the lower limbs (lower legs and feet) are locally numb, the function activity is basically normal, and the curative effect index is less than 80 percent.
The method is effective: the pain of the waist and the pain of the lower limbs are relieved, and the functional part of the waist activity is recovered by 30 percent to 50 percent.
Invalidation: the clinical symptoms and waist dysfunction are not improved before treatment, and the curative effect index is less than 30%.
Results: the traditional Chinese medicine decoction provided by the invention is taken after the 30 cases of lumbar disc herniation patients with qi stagnation and blood stasis are taken for the first day after the patients take the patients, 50mL of the traditional Chinese medicine decoction is taken after a meal for half an hour, 2 times a day and 2 weeks continuously, and the results show that the traditional Chinese medicine symptoms have curative effect recovery of 5 cases, 20 cases and 5 cases with invalid cases, and the total effective rate is 83.3%.
The invention is further illustrated below in connection with typical cases, which in no way limit the invention.
Case one
Zhu Mou Male, seventh people Hospital clinic number in Shanghai city: ME0E
The patient is treated by 'lumbago accompanied with lower limb radiation pain for 1 month'. The patients begin to have discomfort of soreness of waist and back without obvious causes before 1 month, are accompanied with lower limb radiation pain on the right, turn over, turn aside and stand up difficultly, are not durable, and visit the hospital, and the patients can receive sleep, relieve oneself, have dark tongue, thin and white coating and wiry pulse in the course of the disease. The lumbar vertebra MRI prompts the L4/L5 lumbar disc herniation, the lumbar disc herniation is diagnosed, the lumbar vertebra disease qi stagnation and blood stasis syndrome is diagnosed in traditional Chinese medicine, and the traditional Chinese medicine decoction is orally taken for 2 times a day, and 50mL times 14 days each time. The pain in the waist and back and the pain in the lower limb of the right patient after the medicine is taken, the activities of turning over, turning over and standing up are improved, the traditional Chinese medicine decoction is continuously taken orally for 2 times a day, 50mL times 28 days each time, and the symptoms completely disappear after the telephone follow-up.
Case two
Sun Mou female, seventh people hospital clinic number in Shanghai city: v106
The patients were treated by "lumbago with pain in the right lower limb and tingling in the half month after the treatment". The patients can get back pain after carrying heavy things in front of half a month, with numbness of lower limbs, radiation pain, limited movement of waist and back, non-durable movement, aggravation when coughing and sneeze, and then go to hospital, the patients can receive sleep in the course of the disease, and the patients can urinate and regulate, the stool is slightly unsmooth, the tongue is dark, the tongue coating is thin and white, and the pulse is wiry. The lumbar vertebra MRI prompts the L4/L5 and L5/S1 intervertebral disc protrusion, the lumbar disc protrusion is diagnosed, the lumbar vertebra disease is diagnosed by the Chinese medicine, the qi stagnation and blood stasis syndrome is diagnosed by the Chinese medicine, the Chinese medicine decoction is orally taken for 2 times a day, 50mL times 7 days each time, the pain of the waist and the back and the radiation pain of the right lower limb of a patient after the medicine are obviously improved, the activity of the waist and the back is improved, the Chinese medicine decoction is continuously orally taken for 2 times a day, 50mL times 28 days each time, and the symptoms are completely disappeared after the telephone follow-up.
In conclusion, the traditional Chinese medicine composition for treating the lumbar disc herniation is used for treating the lumbar disc herniation caused by qi stagnation and blood stasis, has the effects of promoting qi circulation, removing blood stasis, tonifying kidney and dredging collaterals, and obviously improves clinical symptoms of traditional Chinese medicine.
The foregoing is merely illustrative of the present invention, and the present invention is not limited thereto, and any person skilled in the art will readily recognize that variations or substitutions are within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (7)
1. The traditional Chinese medicine composition for treating the lumbar disc herniation is prepared from the following raw materials in parts by weight: 5-10 parts of nutgrass galingale rhizome, 5-10 parts of corydalis tuber, 5-10 parts of divaricate saposhnikovia root, 5-10 parts of Chinese angelica, 5-10 parts of red paeony root, 1-10 parts of szechuan lovage rhizome, 5-10 parts of pubescent angelica root, 5-10 parts of salt malaytea scurfpea fruit, 5-10 parts of stir-fried ground beetle, 5-10 parts of himalayan teasel root, 5-15 parts of prepared rhizoma cibotii, 5-10 parts of salt stir-fried achyranthes root, 5-15 parts of mistletoe, 1-10 parts of prepared myrrh and 1-10 parts of stir-fried liquorice.
2. The traditional Chinese medicine composition for treating lumbar disc herniation according to claim 1 is characterized by being prepared from the following raw materials in parts by weight: 9 parts of nutgrass galingale rhizome, 7 parts of corydalis tuber, 7 parts of divaricate saposhnikovia root, 9 parts of Chinese angelica, 9 parts of red paeony root, 5 parts of szechuan lovage rhizome, 7 parts of pubescent angelica root, 9 parts of salted malaytea scurfpea fruit, 9 parts of stir-fried ground beetle, 9 parts of himalayan teasel root, 11 parts of prepared rhizoma cibotii, 9 parts of salted stir-fried achyranthes root, 11 parts of mistletoe, 5 parts of prepared myrrh and 5 parts of stir-fried liquorice.
3. Use of a Chinese medicinal composition for treating lumbar disc herniation according to claim 1 or 2 in the preparation of a medicament for treating lumbar disc herniation.
4. The use according to claim 3, wherein the prolapse of lumbar intervertebral disc is a pattern of qi stagnation and blood stasis.
5. The use according to claim 3, wherein the mixture of the active ingredients of the traditional Chinese medicine composition after extraction is prepared into a pharmaceutically acceptable pharmaceutical preparation, and the pharmaceutical preparation comprises the extract of the traditional Chinese medicine composition and a pharmaceutically acceptable pharmaceutical carrier or excipient, and the dosage form comprises tablets, capsules, granules, pills, powder, ointment, suspension or decoction.
6. The use according to claim 5, wherein the pharmaceutical formulation is a decoction, taken orally half an hour after meals, 2 times a day, 50mL each time, for 2 weeks.
7. The use according to claim 6, wherein the preparation method of the decoction comprises the following steps:
step one, mixing the raw materials in the formula 1 or 2, adding water, soaking the medicinal powder for 60 minutes;
continuously adding water into the raw materials of the formula soaked in the step one, soaking the raw materials for 3-4 cm above the medicine surface, decocting with strong fire until the raw materials are boiled, continuously decocting with slow fire for 60 minutes until the residual liquid medicine is concentrated to 100mL, filtering, and taking filtrate for later use;
and thirdly, continuously adding water into the residual medicine obtained in the second step, boiling the medicine after the water is 2-3 cm above the medicine surface, decocting the medicine with strong fire for 60 minutes, filtering the medicine until the residual medicine liquid is concentrated to 100mL, and mixing the filtrate with the filtrate obtained in the second step.
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CN112263608A (en) * | 2020-11-17 | 2021-01-26 | 上海市第七人民医院(上海中医药大学附属第七人民医院) | Traditional Chinese medicine preparation for relieving symptoms of lumbar intervertebral disc protrusion |
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