CN115151292A - 用于递送活性剂的声学雾化器 - Google Patents

用于递送活性剂的声学雾化器 Download PDF

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Publication number
CN115151292A
CN115151292A CN202080082240.4A CN202080082240A CN115151292A CN 115151292 A CN115151292 A CN 115151292A CN 202080082240 A CN202080082240 A CN 202080082240A CN 115151292 A CN115151292 A CN 115151292A
Authority
CN
China
Prior art keywords
liquid
nebulizer
transducer
piezoelectric substrate
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080082240.4A
Other languages
English (en)
Chinese (zh)
Inventor
莱斯利·约
阿姆贾德·雷兹克
阿马林·麦克唐奈
C·奈特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Royal Melbourne Institute of Technology
Original Assignee
Royal Melbourne Institute of Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2019903755A external-priority patent/AU2019903755A0/en
Application filed by Royal Melbourne Institute of Technology Ltd filed Critical Royal Melbourne Institute of Technology Ltd
Publication of CN115151292A publication Critical patent/CN115151292A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0085—Inhalators using ultrasonics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/26—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets
    • B05B1/262—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors
    • B05B1/267—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors the liquid or other fluent material being deflected in determined directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0653—Details
    • B05B17/0676—Feeding means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272—Electro-active or magneto-active materials
    • A61M2205/0294—Piezoelectric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3389—Continuous level detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Special Spraying Apparatus (AREA)
  • Spray Control Apparatus (AREA)
CN202080082240.4A 2019-10-04 2020-10-05 用于递送活性剂的声学雾化器 Pending CN115151292A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019903755A AU2019903755A0 (en) 2019-10-04 Acoustic nebuliser for delivery of active agents
AU2019903755 2019-10-04
PCT/AU2020/051072 WO2021062494A1 (en) 2019-10-04 2020-10-05 Acoustic nebuliser for delivery of active agents

Publications (1)

Publication Number Publication Date
CN115151292A true CN115151292A (zh) 2022-10-04

Family

ID=75336677

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080082240.4A Pending CN115151292A (zh) 2019-10-04 2020-10-05 用于递送活性剂的声学雾化器

Country Status (7)

Country Link
US (1) US20220401662A1 (enExample)
EP (1) EP4037740A4 (enExample)
JP (1) JP7811543B2 (enExample)
CN (1) CN115151292A (enExample)
AU (2) AU2020359673A1 (enExample)
CA (1) CA3153497A1 (enExample)
WO (1) WO2021062494A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115999037A (zh) * 2023-02-17 2023-04-25 西安交通大学医学院第一附属医院 一种超声给药系统
CN116510967A (zh) * 2023-05-06 2023-08-01 南京航空航天大学 一种基于声表面波的雾化芯片

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022097092A1 (en) * 2020-11-06 2022-05-12 Trudell Medical International Surface acoustic wave atomizer with fluid direction and migration prevention
KR20250017240A (ko) 2022-05-27 2025-02-04 사노피 FC-조작을 갖는 NKp46 및 BCMA 변이체에 결합하는 자연 살해(NK) 세포 관여자
GB202410743D0 (en) 2024-07-23 2024-09-04 Acu Flow Ltd Acoustofluidic device, system and method of operation

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5299739A (en) * 1991-05-27 1994-04-05 Tdk Corporation Ultrasonic wave nebulizer
EP0844027A1 (en) * 1995-08-07 1998-05-27 Omron Corporation Atomization apparatus and method utilizing surface acoustic waves
JPH11207224A (ja) * 1998-01-21 1999-08-03 Sharp Corp 粒子径可変生成装置及び粒子径可変生成方法
US6679436B1 (en) * 1998-12-18 2004-01-20 Omron Corporation Sprayer
JP2008104974A (ja) * 2006-10-26 2008-05-08 Matsushita Electric Works Ltd 弾性表面波霧化装置
JP2008104966A (ja) * 2006-10-26 2008-05-08 Seiko Epson Corp 霧化装置、吸引装置
CN106174706A (zh) * 2016-08-31 2016-12-07 云南中烟工业有限责任公司 一种声表面波雾化器
US20170178884A1 (en) * 2015-12-18 2017-06-22 Thermo Fisher Scientific (Bremen) Gmbh Liquid Sample Introduction System and Method, for Analytical Plasma Spectrometer
US20170280771A1 (en) * 2016-03-30 2017-10-05 Altria Client Services Llc Smoking device and method for aerosol-generation
CN112135692A (zh) * 2018-04-05 2020-12-25 皇家墨尔本理工大学 多表面声波雾化器

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6672143B2 (ja) 2013-10-17 2020-03-25 ロイヤル・メルボルン・インスティテュート・オブ・テクノロジーＲｏｙａｌ Ｍｅｌｂｏｕｒｎｅ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ 圧電駆動プラットフォーム
JP7194267B2 (ja) * 2019-04-09 2022-12-21 日本たばこ産業株式会社 エアロゾル供給デバイス

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5299739A (en) * 1991-05-27 1994-04-05 Tdk Corporation Ultrasonic wave nebulizer
EP0844027A1 (en) * 1995-08-07 1998-05-27 Omron Corporation Atomization apparatus and method utilizing surface acoustic waves
EP1602414A2 (en) * 1995-08-07 2005-12-07 Omron Healthcare Co., Ltd. Atomizer and atomizing method utilizing surface acoustic waves
JPH11207224A (ja) * 1998-01-21 1999-08-03 Sharp Corp 粒子径可変生成装置及び粒子径可変生成方法
US6679436B1 (en) * 1998-12-18 2004-01-20 Omron Corporation Sprayer
JP2008104974A (ja) * 2006-10-26 2008-05-08 Matsushita Electric Works Ltd 弾性表面波霧化装置
JP2008104966A (ja) * 2006-10-26 2008-05-08 Seiko Epson Corp 霧化装置、吸引装置
US20170178884A1 (en) * 2015-12-18 2017-06-22 Thermo Fisher Scientific (Bremen) Gmbh Liquid Sample Introduction System and Method, for Analytical Plasma Spectrometer
US20170280771A1 (en) * 2016-03-30 2017-10-05 Altria Client Services Llc Smoking device and method for aerosol-generation
CN106174706A (zh) * 2016-08-31 2016-12-07 云南中烟工业有限责任公司 一种声表面波雾化器
WO2018041106A1 (zh) * 2016-08-31 2018-03-08 云南中烟工业有限责任公司 一种声表面波雾化器
CN112135692A (zh) * 2018-04-05 2020-12-25 皇家墨尔本理工大学 多表面声波雾化器

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115999037A (zh) * 2023-02-17 2023-04-25 西安交通大学医学院第一附属医院 一种超声给药系统
CN116510967A (zh) * 2023-05-06 2023-08-01 南京航空航天大学 一种基于声表面波的雾化芯片

Also Published As

Publication number Publication date
CA3153497A1 (en) 2021-04-08
JP2022550903A (ja) 2022-12-05
AU2026202353A1 (en) 2026-04-16
US20220401662A1 (en) 2022-12-22
EP4037740A1 (en) 2022-08-10
EP4037740A4 (en) 2023-11-01
AU2020359673A1 (en) 2022-04-21
JP7811543B2 (ja) 2026-02-05
WO2021062494A1 (en) 2021-04-08

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