CN115137686B - 一种卸妆级的氨基酸沐浴露 - Google Patents
一种卸妆级的氨基酸沐浴露 Download PDFInfo
- Publication number
- CN115137686B CN115137686B CN202210413143.XA CN202210413143A CN115137686B CN 115137686 B CN115137686 B CN 115137686B CN 202210413143 A CN202210413143 A CN 202210413143A CN 115137686 B CN115137686 B CN 115137686B
- Authority
- CN
- China
- Prior art keywords
- amino acid
- sodium
- surfactant
- peg
- shower gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001413 amino acids Chemical class 0.000 title claims abstract description 26
- 239000006260 foam Substances 0.000 claims abstract description 19
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 15
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229930186217 Glycolipid Natural products 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 7
- 239000000419 plant extract Substances 0.000 claims abstract description 6
- 239000003974 emollient agent Substances 0.000 claims abstract description 5
- 239000003906 humectant Substances 0.000 claims abstract description 5
- 239000003381 stabilizer Substances 0.000 claims abstract description 5
- 239000008367 deionised water Substances 0.000 claims abstract description 3
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- 239000001341 hydroxy propyl starch Substances 0.000 claims description 9
- 235000013828 hydroxypropyl starch Nutrition 0.000 claims description 9
- 239000003205 fragrance Substances 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 7
- 244000274847 Betula papyrifera Species 0.000 claims description 5
- 235000009113 Betula papyrifera Nutrition 0.000 claims description 5
- 235000009109 Betula pendula Nutrition 0.000 claims description 5
- 235000010928 Betula populifolia Nutrition 0.000 claims description 5
- 235000002992 Betula pubescens Nutrition 0.000 claims description 5
- KVTFEOAKFFQCCX-UHFFFAOYSA-N N-hexadecanoylglycine Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(O)=O KVTFEOAKFFQCCX-UHFFFAOYSA-N 0.000 claims description 5
- 239000001140 aloe barbadensis leaf extract Substances 0.000 claims description 5
- 229920001577 copolymer Polymers 0.000 claims description 5
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 229940075639 palmitoyl glycine Drugs 0.000 claims description 5
- 229940079988 potassium cocoyl glycinate Drugs 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 229910052708 sodium Inorganic materials 0.000 claims description 5
- 239000011734 sodium Substances 0.000 claims description 5
- 229940048109 sodium methyl cocoyl taurate Drugs 0.000 claims description 5
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- MRUAUOIMASANKQ-UHFFFAOYSA-O carboxymethyl-[3-(dodecanoylamino)propyl]-dimethylazanium Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)=O MRUAUOIMASANKQ-UHFFFAOYSA-O 0.000 claims description 4
- 229940075468 lauramidopropyl betaine Drugs 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 4
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 229940083542 sodium Drugs 0.000 claims description 3
- 244000060011 Cocos nucifera Species 0.000 claims description 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- 108010077895 Sarcosine Proteins 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- QNAYBMKLOCPYGJ-UHFFFAOYSA-M alaninate Chemical compound CC(N)C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-M 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 2
- 239000004359 castor oil Substances 0.000 claims description 2
- 235000019438 castor oil Nutrition 0.000 claims description 2
- 239000003240 coconut oil Substances 0.000 claims description 2
- 235000019864 coconut oil Nutrition 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 2
- GLSRFBDXBWZNLH-UHFFFAOYSA-L disodium;2-chloroacetate;2-(4,5-dihydroimidazol-1-yl)ethanol;hydroxide Chemical compound [OH-].[Na+].[Na+].[O-]C(=O)CCl.OCCN1CCN=C1 GLSRFBDXBWZNLH-UHFFFAOYSA-L 0.000 claims description 2
- 239000000194 fatty acid Substances 0.000 claims description 2
- 229930195729 fatty acid Natural products 0.000 claims description 2
- 150000004665 fatty acids Chemical class 0.000 claims description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 2
- 229940044591 methyl glucose dioleate Drugs 0.000 claims description 2
- LPUQAYUQRXPFSQ-DFWYDOINSA-M monosodium L-glutamate Chemical compound [Na+].[O-]C(=O)[C@@H](N)CCC(O)=O LPUQAYUQRXPFSQ-DFWYDOINSA-M 0.000 claims description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 2
- 239000004006 olive oil Substances 0.000 claims description 2
- 235000008390 olive oil Nutrition 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 2
- 239000010452 phosphate Substances 0.000 claims description 2
- 108700004121 sarkosyl Proteins 0.000 claims description 2
- 229940096501 sodium cocoamphoacetate Drugs 0.000 claims description 2
- 229940079781 sodium cocoyl glutamate Drugs 0.000 claims description 2
- 229940045944 sodium lauroyl glutamate Drugs 0.000 claims description 2
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 2
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims description 2
- 229940060304 sodium myristoyl sarcosinate Drugs 0.000 claims description 2
- IWIUXJGIDSGWDN-UQKRIMTDSA-M sodium;(2s)-2-(dodecanoylamino)pentanedioate;hydron Chemical compound [Na+].CCCCCCCCCCCC(=O)N[C@H](C([O-])=O)CCC(O)=O IWIUXJGIDSGWDN-UQKRIMTDSA-M 0.000 claims description 2
- KHCOJQDJOCNUGV-UHFFFAOYSA-M sodium;2-[methyl(tetradecanoyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCCC(=O)N(C)CC([O-])=O KHCOJQDJOCNUGV-UHFFFAOYSA-M 0.000 claims description 2
- 229940032094 squalane Drugs 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 229940093609 tricaprylin Drugs 0.000 claims description 2
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims description 2
- 239000004034 viscosity adjusting agent Substances 0.000 claims description 2
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims 1
- 229940035437 1,3-propanediol Drugs 0.000 claims 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 1
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims 1
- GOJYXPWOUJYXJC-UHFFFAOYSA-M sodium;2-[1-(2-hydroxyethyl)-2-undecyl-4,5-dihydroimidazol-1-ium-1-yl]acetate;hydroxide Chemical compound [OH-].[Na+].CCCCCCCCCCCC1=NCC[N+]1(CCO)CC([O-])=O GOJYXPWOUJYXJC-UHFFFAOYSA-M 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 abstract description 13
- 230000007794 irritation Effects 0.000 abstract description 8
- 208000003251 Pruritus Diseases 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 6
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 3
- 230000007815 allergy Effects 0.000 abstract description 3
- 230000003749 cleanliness Effects 0.000 abstract description 3
- 230000007803 itching Effects 0.000 abstract description 3
- 208000026935 allergic disease Diseases 0.000 abstract description 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010040880 Skin irritation Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 231100000344 non-irritating Toxicity 0.000 abstract 1
- 230000036556 skin irritation Effects 0.000 abstract 1
- 231100000475 skin irritation Toxicity 0.000 abstract 1
- 239000000499 gel Substances 0.000 description 16
- 239000000047 product Substances 0.000 description 16
- 230000000052 comparative effect Effects 0.000 description 10
- 210000003743 erythrocyte Anatomy 0.000 description 9
- 238000011156 evaluation Methods 0.000 description 9
- 238000003756 stirring Methods 0.000 description 7
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 6
- -1 polyethylene Polymers 0.000 description 6
- 239000000344 soap Substances 0.000 description 6
- 230000000638 stimulation Effects 0.000 description 5
- 238000010998 test method Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 206010018910 Haemolysis Diseases 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 230000008588 hemolysis Effects 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 3
- 210000000170 cell membrane Anatomy 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002563 ionic surfactant Substances 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229960005323 phenoxyethanol Drugs 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 239000006071 cream Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- HGUFODBRKLSHSI-UHFFFAOYSA-N 2,3,7,8-tetrachloro-dibenzo-p-dioxin Chemical compound O1C2=CC(Cl)=C(Cl)C=C2OC2=C1C=C(Cl)C(Cl)=C2 HGUFODBRKLSHSI-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 231100000635 Draize test Toxicity 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940100524 ethylhexylglycerin Drugs 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
本发明公开了一种卸妆级的氨基酸沐浴露，属于日化技术领域，按重量百分比计，包括以下组分：阴离子表面活性剂5％‑35％、生物糖脂1.5‑2％、两性表面活性剂1％‑6％、粘度调节剂1‑5％、润肤剂4‑10％、调理剂0.5‑1％、泡沫稳定剂0.1‑1.5％、保湿剂1.0‑5.0％、植物提取物0.6‑1％、余量为去离子水；本发明通过生物糖脂与氨基酸表面活性剂之间的配合使用，在降低了刺激性的基础上，进一步提高了氨基酸表面活性剂的清洁性和温和性，提高产品的卸妆能力；本发明的阴离子表面活性剂采用氨基酸表面活性剂，温和无刺激，同时植物提取物具有的止痒抗炎，减少秋冬季皮肤瘙痒；解决了现有的沐浴露对皮肤刺激相对较大，对敏感人群容易引起过敏和瘙痒的问题。
Description
技术领域
本发明涉及日化技术领域，具体是一种卸妆级的氨基酸沐浴露。
背景技术
目前中国市场上的沐浴露多为硫酸盐表活和皂基类的产品，硫酸盐表活低成本易增稠且去污能力强泡沫丰富，皂基类产品泡沫丰富，易冲洗。但是，硫酸盐表活体系冲洗感欠佳，还可能会带入副产物二噁英，增加潜在风险。再者，皂基类产品对皮肤刺激相对较大，对敏感人群容易引起过敏和瘙痒，尤其是秋冬天更是如此。
近几年，洗护个人护理品市场向着天然、温和、功效性方向发展；氨基酸、无硅、植物成分、护肤、卸妆等字眼充值着洗护市场，受此影响，沐浴露产品也在悄悄升级，不满足于传统清洁意义，具有卸妆清洁能力，刺激性更低，更温和同时具有护肤的效果的产品更容易受到消费者的青睐。
因此，开发一款温和沐浴产品，同时解决此类配方如泡沫、增稠、洁净力在完善产品线和市场开发上具有重要意义。
发明内容
本发明的目的在于提供一种卸妆级的氨基酸沐浴露，以解决上述背景技术中提出的问题。
为实现上述目的，本发明提供如下技术方案：
一种卸妆级的氨基酸沐浴露，按重量百分比计，包括以下组分：
阴离子表面活性剂5％-35％、生物糖脂1.5-2％、两性表面活性剂1％-6％、粘度调节剂1-5％、润肤剂4-10％、调理剂0.5-1％、泡沫稳定剂0.1-1.5％、保湿剂1.0-5.0％、植物提取物0.6-1％、余量为去离子水。
作为本发明进一步的方案：所述组分还包括香料和防腐剂。
作为本发明进一步的方案：所述阴离子表面活性剂为氨基酸阴离子表面活性剂。
作为本发明进一步的方案：所述阴离子表面活性剂为月桂酰肌氨酸钠、肉豆蔻肌氨酸钠、月桂酰谷氨酸钠、椰油酰谷氨酸钠、椰油酰甘氨酸钾、椰油酰丙氨酸钠和甲基椰油酰基牛磺酸钠中一种或几种。
作为本发明进一步的方案：所述两性表面活性剂为月桂酰胺丙基甜菜碱、椰油两性基乙酸钠、月桂酰两性基乙酸钠、椰油酰两性基乙酸和月桂酰两性基二乙酸二钠中的一种或几种。
作为本发明进一步的方案：所述粘度调节剂为椰子油脂肪酸单乙醇酰胺CMEA、丙烯酸酯类共聚物、羟丙基淀粉、PEG-120甲基葡糖二油酸酯、PEG-120甲基葡糖三油酯酸、PEG-120甲基葡糖三油酸酯和1,3-丙二醇中的一种或几种。
作为本发明进一步的方案：所述润肤剂为羟丙基淀粉、双淀粉磷酸酯、角鲨烷、橄榄油、氢化蓖麻油、氢化椰子油、棕榈酰甘氨酸、甘油三辛酸酯\癸酸酯、16\18醇中的一种或几种。
作为本发明进一步的方案：所述调理剂为聚季铵盐-10、聚季铵盐-7、聚季铵盐-39、聚季铵盐-47中的一种或几种。
作为本发明进一步的方案：所述的泡沫稳定剂为PEG-14M、PEG-7M、PEG-45M、羟丙基淀粉、羟丙基甲基纤维素中的一种或几种。
作为本发明进一步的方案：所述保湿剂为甘油，所述植物提取物包括白桦树汁和库拉索芦荟叶汁。
与现有技术相比，本发明的有益效果是：本发明实用性强，本发明去除了皂基和硫酸盐表面活性剂，避免了刺激性过重导致的皮肤过敏问题；本发明的阴离子表面活性剂采用氨基酸表面活性剂，温和无刺激，且所述生物糖脂与氨基酸表面活性剂之间的配合使用，具有协同增效的作用，在降低了氨基酸表面活性剂的刺激性的基础上，进一步提高了氨基酸表面活性剂的清洁性和温和性，提高产品的卸妆能力，还添加了大量的润肤成分，在降低刺激性的同时，补充调理，使其有自然健康的滋润保湿效果，同时植物提取物具有的止痒抗炎，减少秋冬季皮肤瘙痒；还添加有两性表面活性剂，两性表面活性剂与阴离子表面活性剂协同作用，两性表面活性剂起到增加泡沫和降低阴离子表面活性剂高发泡引起的刺激；本发明的表活搭配有非常好的清洁效果，去除淡状粉底、BB霜和防晒霜的效果比传统体系效果更好。
具体实施方式
实施例1
一种卸妆级的氨基酸沐浴露，按重量百分比计，包括以下组分：
生物糖脂2％、椰油酰甘氨酸钾20％、甲基椰油酰基牛磺酸钠10％、月桂酰胺丙基甜菜碱6％、羟丙基淀粉1.5％、丙烯酸酯类共聚物1.0％、棕榈酰甘氨酸5.5％、聚季铵盐-71.0％、甘油4％、聚乙二醇-14M 0.1％、苯氧乙醇\乙基己基甘油复配防腐剂0.8％、香精0.4％、白桦树汁0.5％、库拉索芦荟叶汁0.5％、余量为水，组分总共为100％，用常规制备沐浴露的方法制备而成。
实施例2
一种卸妆级的氨基酸沐浴露，按重量百分比计，包括以下组分：
生物糖脂1.5％、椰油酰甘氨酸钾10％、甲基椰油酰基牛磺酸钠20％、月桂酰胺丙基甜菜碱3％、椰油酰两性基乙酸钠3％、羟丙基淀粉1.0％、丙烯酸酯类共聚物1.0％、棕榈酰甘氨酸4.0％、聚季铵盐-7 0.5％、甘油5％、聚乙二醇-14M 0.1％、苯氧乙醇\乙基己基甘油复配防腐剂0.8％、香精0.4％、白桦树汁0.3％、库拉索芦荟叶汁0.3％、余量为水，组分总共为100％，用常规制备沐浴露的方法制备而成。
实施例3
一种卸妆级的氨基酸沐浴露，按重量百分比计，包括以下组分：
生物糖脂2％、椰油酰甘氨酸钾25％、甲基椰油酰基牛磺酸钠20％、椰油酰两性基乙酸钠6％、羟丙基淀粉1.5％、丙烯酸酯类共聚物0.6％、棕榈酰甘氨酸5.0％、聚季铵盐-70.5％、甘油3％、聚乙二醇-14M 0.1％、苯氧乙醇\乙基己基甘油复配防腐剂0.8％、香精0.4％、白桦树汁0.5％、库拉索芦荟叶汁0.5％、余量为水，组分总共为100％，用常规制备沐浴露的方法制备而成。
对比例1
市场上的沐浴露1的配方如下表1
表1
对比例1的制备工艺如下：
1.将B相混合加热至75度,依次加入A相，继续搅拌15分钟溶解完全，降温。
2. 45度依次加入C相，充分搅拌均匀，检测体系pH7.0-7.5,用盐调节体系粘度至需要范围，室温出料。
对比例2
市场上的沐浴露2的配方如下表2
表2
对比例2的制备工艺如下：
1、将A相、B相分别混合加热至70℃溶解完全备用(根据失水情况需补加水)；
2、搅拌下将B相加入A相中，保温80℃反应20分钟。
3、加入C相(A88用水稀释加入)、D相、E相,保温搅拌20分钟至溶解完全，降温。
4、降低搅拌速度继续降温搅拌至常温，加入余项,充分搅拌均匀。
本发明实施例中的生物糖脂的L/D值＞100，不刺激，非常温和，不会引起血红细胞的裂解。
测试方法
泡沫高度测试方法：采用罗氏(Ross--Miles)泡沫测定仪的测试方法进行测试，分别测试起始泡沫高度，1分钟后泡沫高度和5分钟后泡沫高度，然后取平均值。结果见表3。
温和性测试方法：采用红细胞溶血实验(Red blood cell test RBC)方法，该方法是Draize实验替代方法之一，基本原理是测定化学物对细胞膜的损伤和因此导致的细胞膜渗透性的改变，通过测定从红细胞中漏出的血红蛋白的量来评价细胞膜的损伤程度，该损伤程度与产品的刺激性具有直接相关性。国际上主要将RBC实验用于化妆品产品及原料等化学品的眼刺激性研究。因此本发明通过以红细胞溶血实验方法测定配方的温和性，并形成对比，测试产品温和性。具体方法为：使用分光光度法测定化学物作用后的红细胞悬液的吸光度，可计算出溶血率和H50值(即使50％红细胞发生溶血的受试物的浓度值)。H50值小，即加入较少量的样品就能发生明显的溶血现象，表明样品刺激性大，温和性差。H50值大，表明样品刺激性小，温和性增加。结果见表3。
表3
从表3可见，本发明的实施例的罗氏泡沫高度均在160mm以上，而对比例硫酸盐和皂基沐浴露的罗氏泡沫高度也在160mm左右，本发明的泡沫高度与传统沐浴露无明显差别、甚至略好一点。
从表1可见，本发明的实施例一-三的H50值均在366μg/ml，实施例一更是高达373μg/ml，而对比例一和二的H50值仅在270μg/ml以下，本发明的温和性均明显优于对比例。
感受性评测
将上述实施例1、实施例2、实施例3、对比例1、对比例2的产品进行对比试验，包括香味、温和性、易冲洗性能和保湿的评价：
1、评价方法：检测采取志愿者试用，通过感官评价的方式进行。志愿者均为18-20周岁人员，男女均等，可独立进行实验。分为5组人，每组10人。
2、香味测评：在使用前和使用过程中，对香味的喜爱程度；
温和性测评：在试洗过程中，感受产品的温和性能；
易冲洗性能测评：感受沐浴露是否容易冲洗干净；
保湿性测评：通过抚触皮肤，感受皮肤用后的保湿性能；
3、5组人员随机对应使用一项产品。通过对实施例一、实施例二、实施例三、对比例一、对比例二的产品进行香味、温和性、易冲洗性能和用后保湿性能打分，每项总分为10分，最高分10分，最低分1分，取平均分。评价周期为4周。评价结果见下表4所示。
表4
由表2可以看出，实施例一、二和三表现出比对比例一和二更加优越的温和性和保湿性，消费者体验的整体满意度是比较高的。
综上所述：本发明无硫酸盐低刺激天然香氛沐浴露可替代目前被广泛应用的硫酸盐沐浴露和皂基沐浴露，减少了刺激和过度脱脂引起的干燥和过敏，有效缓解了秋冬季使用沐浴露皮肤容易瘙痒的问题；两性表面活性剂与阴离子表面活性剂协同作用，两性表面活性剂起到增加泡沫和降低阴离子表面活性剂高发泡引起的刺激；所述生物糖脂与氨基酸表面活性剂之间的配合使用，具有协同增效的作用，在降低了氨基酸表面活性剂的刺激性的基础上，进一步提高了氨基酸表面活性剂的清洁性和温和性，提高产品的卸妆能力。
本发明泡沫丰富、稳定，产品性质更温和，更安全健康，有效清洗的同时让消费者有更好的用后体验。
本发明并不局限于上述实施方式，如果对本发明的各种改动或变型不脱离本发明的精神和范围，倘若这些改动和变型属于本发明的权利要求和等同技术范围之内，则本发明也意图包含这些改动和变型。
Claims (7)
1.一种卸妆级的氨基酸沐浴露，按重量百分比计，包括以下组分：
阴离子表面活性剂5％-35％、生物糖脂1.5-2％、两性表面活性剂1％-6％、粘度调节剂1-5％、润肤剂4-10％、调理剂0.5-1％、泡沫稳定剂0.1-1.5％、保湿剂1.0-5.0％、植物提取物0.6-1％、余量为去离子水；
所述阴离子表面活性剂为氨基酸阴离子表面活性剂；
所述阴离子表面活性剂为月桂酰肌氨酸钠、肉豆蔻肌氨酸钠、月桂酰谷氨酸钠、椰油酰谷氨酸钠、椰油酰甘氨酸钾、椰油酰丙氨酸钠和甲基椰油酰基牛磺酸钠中一种或几种；
所述保湿剂为甘油，所述植物提取物包括白桦树汁和库拉索芦荟叶汁。
2.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述组分还包括香料和防腐剂。
3.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述两性表面活性剂为月桂酰胺丙基甜菜碱、椰油两性基乙酸钠、月桂酰两性基乙酸钠、椰油酰两性基乙酸和月桂酰两性基二乙酸二钠中的一种或几种。
4.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述粘度调节剂为椰子油脂肪酸单乙醇酰胺CMEA、丙烯酸酯类共聚物、羟丙基淀粉、PEG-120甲基葡糖二油酸酯、PEG-120甲基葡糖三油酯酸、PEG-120甲基葡糖三油酸酯和1,3-丙二醇中的一种或几种。
5.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述润肤剂为羟丙基淀粉、双淀粉磷酸酯、角鲨烷、橄榄油、氢化蓖麻油、氢化椰子油、棕榈酰甘氨酸、甘油三辛酸酯\癸酸酯、16\18醇中的一种或几种。
6.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述调理剂为聚季铵盐-10、聚季铵盐-7、聚季铵盐-39、聚季铵盐-47中的一种或几种。
7.根据权利要求1所述的一种卸妆级的氨基酸沐浴露，其特征在于，所述的泡沫稳定剂为PEG-14M、PEG-7M、PEG-45M、羟丙基淀粉、羟丙基甲基纤维素中的一种或几种。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210413143.XA CN115137686B (zh) | 2022-04-20 | 2022-04-20 | 一种卸妆级的氨基酸沐浴露 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210413143.XA CN115137686B (zh) | 2022-04-20 | 2022-04-20 | 一种卸妆级的氨基酸沐浴露 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115137686A CN115137686A (zh) | 2022-10-04 |
| CN115137686B true CN115137686B (zh) | 2023-08-25 |
Family
ID=83407158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210413143.XA Active CN115137686B (zh) | 2022-04-20 | 2022-04-20 | 一种卸妆级的氨基酸沐浴露 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115137686B (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3146408A1 (fr) * | 2023-03-06 | 2024-09-13 | L'oreal | Composition nettoyante d'origine naturelle |
| WO2024141844A1 (en) * | 2022-12-27 | 2024-07-04 | L'oreal | Foaming cleansing compositions |
| FR3146407A1 (fr) * | 2023-03-06 | 2024-09-13 | L'oreal | Composition nettoyante moussante |
| CN118078729B (zh) * | 2024-04-23 | 2024-07-16 | 醇度国际生物科技(北京)有限公司 | 一种同时具有保湿和护肤作用的卸妆清洁霜及其制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110074992A (zh) * | 2019-04-24 | 2019-08-02 | 上海中翊日化有限公司 | 透明皂基沐浴露及制备方法 |
| CN112891252A (zh) * | 2021-04-23 | 2021-06-04 | 广州市科能化妆品科研有限公司 | 一种温和止痒沐浴组合物及其制备方法 |
-
2022
- 2022-04-20 CN CN202210413143.XA patent/CN115137686B/zh active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110074992A (zh) * | 2019-04-24 | 2019-08-02 | 上海中翊日化有限公司 | 透明皂基沐浴露及制备方法 |
| CN112891252A (zh) * | 2021-04-23 | 2021-06-04 | 广州市科能化妆品科研有限公司 | 一种温和止痒沐浴组合物及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115137686A (zh) | 2022-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN115137686B (zh) | 一种卸妆级的氨基酸沐浴露 | |
| CN111631974B (zh) | 皂氨型洁面产品及其制备方法 | |
| CN110638715B (zh) | 一种男士洁面膏及其制备方法 | |
| CN110090182A (zh) | 一种温和沐浴油及其制备方法 | |
| CN108685734A (zh) | 一种无硫酸盐无硅低刺激温和植物养发香波 | |
| CN114392204A (zh) | 一种皮肤清洁组合物及其制备方法与应用 | |
| CN110279623A (zh) | 一种温和舒敏氨基酸洁面乳及其制备方法 | |
| CN105853271A (zh) | 含荼薇花提取物的个人清洁组合物 | |
| CN111631987A (zh) | 一种具有滋润保湿抗敏功效的组合物及其应用 | |
| CN116370349B (zh) | 一种氨基酸洗面奶及其制备方法应用 | |
| CN109350561B (zh) | 一种稳定且有视觉化清洁功效的无泡沫洗面霜 | |
| CN117159411A (zh) | 一种高植物油含量氨基酸沐浴乳及其制备 | |
| CN114366693B (zh) | 一种婴童洗发沐浴露 | |
| CN113616553B (zh) | 一种温和水润稳定的皂基洁面膏及其制备方法 | |
| CN111956517B (zh) | 一种洗面奶及其制备方法 | |
| CN115404134A (zh) | 一种透明自增稠清洁组合物 | |
| EP3505218B1 (en) | A gentle detergent composition for greasy and acneic skins | |
| CN114533603A (zh) | 一种滋养保湿沐浴乳 | |
| CN113476339A (zh) | 一种卸妆清洁双效合一的自发泡养肤洁面啫喱的配方 | |
| CN115590798B (zh) | 一种具有抗敏和嫩肤功效的双组分沐浴露及其制备方法 | |
| CN119632860B (zh) | 一种皮肤清洁组合物及其制备方法与应用 | |
| CN110101609A (zh) | 一种含山茶籽油的温和无硅油洗发沐浴露及其制备方法 | |
| CN118593411B (zh) | 一种温和水润洁面乳及其制备方法 | |
| CN115154369A (zh) | 一种发热洁面产品及其制备方法 | |
| CN115737459A (zh) | 一种具有保湿润泽养肤功效的身体清洁组合物及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |