CN115132394A - RI manufacturing apparatus and target accommodating apparatus - Google Patents

RI manufacturing apparatus and target accommodating apparatus Download PDF

Info

Publication number
CN115132394A
CN115132394A CN202210318662.8A CN202210318662A CN115132394A CN 115132394 A CN115132394 A CN 115132394A CN 202210318662 A CN202210318662 A CN 202210318662A CN 115132394 A CN115132394 A CN 115132394A
Authority
CN
China
Prior art keywords
target
accommodating
cooling
irradiation axis
flow path
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210318662.8A
Other languages
Chinese (zh)
Inventor
上田隆正
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Heavy Industries Ltd
Original Assignee
Sumitomo Heavy Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Heavy Industries Ltd filed Critical Sumitomo Heavy Industries Ltd
Publication of CN115132394A publication Critical patent/CN115132394A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001Recovery of specific isotopes from irradiated targets
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • A61B6/037Emission tomography
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21KTECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K5/00Irradiation devices
    • G21K5/08Holders for targets or for other objects to be irradiated

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Particle Accelerators (AREA)
  • Nuclear Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to an RI manufacturing apparatus and a target accommodating apparatus, and provides a target accommodating apparatus capable of improving cooling efficiency and an RI manufacturing apparatus capable of improving nuclear reaction efficiency. The RI manufacturing device (1) is provided with cooling flow paths (46, 48), wherein the cooling flow paths (46, 48) can be used for flowing cooling medium, so that the accommodating part (3) is cooled from the outer peripheral sides of the heat transfer wall parts (41, 42) through the heat transfer wall parts (41, 42) which are arranged around the irradiation axis (RL) relative to the accommodating part (3). At this time, by flowing the cooling medium through the cooling channels (46, 48), the target in the housing section (3) can be cooled from a position further outside than the housing section with respect to the irradiation axis via the heat transfer wall sections (41, 42) surrounding the irradiation axis (RL). In this way, the target can be cooled from different directions by the internal spaces (31A, 31B) and the cooling channels (46, 48).

Description

RI manufacturing apparatus and target accommodating apparatus
Technical Field
The present application claims priority based on japanese patent application No. 2021-055409, applied on 3/29/2021. The entire contents of this Japanese application are incorporated by reference into this specification.
The present invention relates to a target accommodating device.
Background
A radioisotope used in a test drug for PET examination using Positron Emission Tomography (PET) is manufactured using a radiation source such as a cyclotron installed at a position close to an examination room in a hospital. Specifically, a particle beam (for example, a proton beam, a deuterium beam, or the like) from a radiation source is irradiatedThe beam is directed to a target holder through a target (e.g., target water) held in the target holder 18 O water)) to produce a radioisotope. The radioactive isotope thus produced is added to a predetermined compound (for example, Fluorodeoxyglucose (FDG)), or a part thereof is replaced and synthesized, thereby producing a test drug.
As an RI production apparatus for producing such a radioisotope, there is known an apparatus including: a container for containing a liquid target; and a flow path for cooling the housing section from one side of an irradiation axis of the particle beam (see, for example, patent document 1).
Patent document 1: japanese patent laid-open publication No. 2013-246131
Here, the target is at a high temperature by the irradiation of the particle beam. In contrast, the efficiency of the nuclear reaction can be improved by improving the cooling efficiency of the cooling target. Therefore, a target accommodating apparatus capable of improving cooling efficiency and an RI manufacturing apparatus capable of improving efficiency of nuclear reaction are required.
Disclosure of Invention
The present invention has been made in view of the above circumstances, and an object thereof is to provide a target accommodating apparatus capable of improving cooling efficiency and an RI manufacturing apparatus capable of improving efficiency of nuclear reaction.
In order to achieve the above object, an RI production apparatus according to an aspect of the present invention is an RI production apparatus for producing radioisotopes by nuclear reaction of a target irradiated with a particle beam, the RI production apparatus including: an accommodating unit for accommodating a target at an irradiation position of a particle beam; a 1 st flow path through which a cooling medium can flow so as to cool the housing section from one side with respect to an irradiation axis of the particle beam; and a 2 nd flow path through which a cooling medium can flow so as to cool the housing section from a position outside the housing section with respect to the irradiation axis via at least a part of a wall section provided around the irradiation axis with respect to the housing section.
The RI manufacturing apparatus includes a 1 st flow path through which a cooling medium can flow so as to cool the housing part from one side with respect to an irradiation axis of the particle beam. Thus, the target in the housing section can be cooled from the side opposite to the irradiation axis by passing the cooling medium through the flow channel 1. The RI manufacturing apparatus further includes a 2 nd flow path through which the cooling medium can flow so as to cool the housing section from a position further outside than the housing section with respect to the irradiation axis via at least a part of a wall portion provided around the irradiation axis with respect to the housing section. At this time, the cooling medium is caused to flow through the flow channel 2, whereby heat is discharged from the housing portion from the inside to the outside with respect to the irradiation axis via the wall portion surrounding the irradiation axis, whereby the target in the housing portion can be cooled. In this way, the target can be cooled from different directions through the 1 st channel and the 2 nd channel. Therefore, the cooling efficiency of the target can be improved, and thus the efficiency of the nuclear reaction of the target can be improved.
The 2 nd channel may be configured to cool a portion of the accommodating portion capable of accommodating the liquid target. At this time, the 2 nd flow path cools the liquid target which becomes a high temperature by the irradiation of the particle beam, thereby suppressing the evaporation of the liquid target. Therefore, the efficiency of the nuclear reaction of the liquid target can be improved.
The 2 nd flow path may be configured to cool a portion of the housing portion capable of housing the gas target. At this time, the 2 nd flow path can liquefy the gas target by cooling it. Therefore, the efficiency of the nuclear reaction can be improved by increasing the amount of the liquid target.
The accommodating portion may have: a 1 st containing portion capable of containing a liquid target; and a 2 nd accommodating portion which communicates with the 1 st accommodating portion and can accommodate the gas target, wherein the 2 nd flow path can cool the accommodating portion from the side opposite to the 1 st flow path with respect to the irradiation axis through the 2 nd accommodating portion. At this time, the liquid target in the 1 st housing part is evaporated by the irradiated particle beam and stored in the 2 nd housing part as a gas target. In contrast, the 1 st channel and the 2 nd channel can cool the gas target from both sides with respect to the irradiation axis. Thereby, the gas target can be liquefied by cooling and returned to the 1 st accommodating section as the liquid target. Therefore, the efficiency of the nuclear reaction can be improved by increasing the amount of the liquid target.
The second flow path 2 may be provided with a member for blocking the flow of the cooling medium. In this case, the flow of the cooling medium in the 2 nd flow path is blocked by the member, whereby the laminar flow can be replaced by the turbulent flow to improve the cooling efficiency.
A target accommodating apparatus according to an aspect of the present invention is a target accommodating apparatus that accommodates a target that can produce a radioisotope by a nuclear reaction by being irradiated with a particle beam, the target accommodating apparatus including: an accommodating portion accommodating the target; a 1 st flow path through which a cooling medium can flow so as to cool the housing section from one side with respect to an irradiation axis of the particle beam when the particle beam is irradiated to the target; and a 2 nd flow path through which a cooling medium can flow so as to cool the housing section from an outer peripheral side of a wall section provided around the irradiation axis with respect to the housing section via at least a part of the wall section.
The target accommodating device is provided with a 1 st flow path, and the 1 st flow path can be used for flowing a cooling medium so as to cool the accommodating part from one side relative to an irradiation axis of the particle beam. Thus, the cooling medium can be flowed through the flow channel 1, thereby cooling the target in the housing portion from the side opposite to the irradiation axis. The target accommodating device further includes a 2 nd flow path through which a cooling medium can flow so as to cool the accommodating portion from a position further outside than the accommodating portion with respect to the irradiation axis via at least a part of a wall portion provided around the irradiation axis with respect to the accommodating portion. At this time, the cooling medium is caused to flow through the flow path 2, whereby the target in the housing portion can be cooled from the outer peripheral side via the wall portion surrounding the irradiation axis. In this way, the target can be cooled from different directions through the 1 st channel and the 2 nd channel. Therefore, the cooling efficiency of the target can be improved.
ADVANTAGEOUS EFFECTS OF INVENTION
According to the present invention, it is possible to provide a target accommodating apparatus capable of improving cooling efficiency and an RI manufacturing apparatus capable of improving efficiency of nuclear reaction.
Drawings
Fig. 1 is a sectional view of an RI manufacturing apparatus according to an embodiment of the present invention.
Fig. 2 is a top view of an RI manufacturing apparatus.
Fig. 3 is a sectional view of the target accommodating apparatus according to the present embodiment.
Fig. 4 is a perspective view of the target accommodating device.
Fig. 5 is a diagram illustrating the flow of the cooling medium of the target accommodating device.
Fig. 6 is an enlarged view of the cooling flow path.
Description of the symbols
1-RL manufacturing apparatus, 3-accommodating section, 10-target accommodating apparatus, 31A, 31B-internal space (1 st flow path), 41, 42-heat transfer wall section, 46, 48-cooling flow path (2 nd flow path).
Detailed Description
Hereinafter, embodiments for carrying out the present invention will be described in detail with reference to the drawings. In the description of the drawings, the same elements are denoted by the same reference numerals, and redundant description is omitted.
Fig. 1 is a sectional view of an RI production apparatus 1. The RI manufacturing apparatus 1 includes a target accommodating apparatus 10 as an embodiment of the RI manufacturing apparatus of the present invention. The RI production apparatus 1 produces a Radioisotope (RI). The RI manufacturing apparatus 1 can be used as, for example, a PET cyclotron, and the RI manufactured by the RI manufacturing apparatus 1 is used, for example, for manufacturing radiopharmaceuticals (including radiopharmaceutical products) that are radioisotope-labeled compounds (RI compounds). As a radioisotope-labeled compound used in PET examination (positron emission tomography examination) in hospitals and the like, there are those 18 F-FLT (fluorothymidine), 18 F-FMISO (fluoromethalone nidazole), 11 C-Raclepride and the like.
The RI manufacturing apparatus 1 is a so-called self-shielding type particle accelerator system, and includes an accelerator (cyclotron) 2 that accelerates charged particles, and a self-shielding body 6 that is a radiation shielding member (wall body) that surrounds the accelerator 2 to shield radiation. In the internal space S surrounded by the self-shielding body 6, a target accommodating apparatus 10 for manufacturing RI, a vacuum pump 4 for evacuating the inside of the accelerator 2, and the like are arranged in addition to the accelerator 2. In the internal space, accessories necessary for the operation of the accelerator 2, accessories used for cooling the target container 10, and the like are disposed.
The accelerator 2 is a so-called vertical cyclotron, and has a pair of magnetic poles, a vacuum box, and an annular yoke surrounding the pair of magnetic poles and the vacuum box. The pair of magnetic poles are partially opposed to each other at a predetermined interval on the upper surface in the vacuum chamber. In the gap between these pair of magnetic poles, charged particles such as hydrogen ions are multiply accelerated. The vacuum pump 4 is used to maintain a vacuum environment inside the accelerator 2, for example, fixed to a side portion of the accelerator 2. The accelerator 2 emits a charged particle beam in an irradiation direction indicated by an arrow B in the figure.
The target container 10 receives the charged particle beam irradiated from the accelerator 2 to produce RI, and contains a raw material (e.g., target water; 18 o water). As shown in fig. 1 and 2, the target accommodating device 10 is generally fixed to a side portion of the accelerator 2. The RI manufacturing apparatus 1 of the present embodiment includes 2 target accommodating apparatuses 10 disposed on both sides with an accelerator 2 interposed therebetween. For example, the target accommodating device 10 disposed on the left side in the figure is disposed on the upper layer side, and the target accommodating device 10 disposed on the right side in the figure is disposed on the lower layer side (see fig. 2). The target accommodating device 10 is covered by a target shield 7 provided to the accelerator 2. The self-shield 6 is formed of a plurality of parts and is formed to cover the accelerator 2 and the target accommodating device 10.
Next, the target accommodating apparatus 10 provided in the RI manufacturing apparatus 1 according to the present invention will be described in further detail with reference to fig. 3 and 4. Fig. 3 is a sectional view of the target accommodating apparatus 10 according to the present embodiment. Fig. 3 is a sectional view of the target accommodating device 10 cut at the position of the irradiation axis RL. Fig. 4 is a sectional perspective view of a part of the target accommodating device 10. Reference is made primarily to fig. 3, with appropriate reference to fig. 4.
As shown in fig. 3, the target accommodating device 10 according to the present embodiment includes a foil 2, an accommodating portion 3, and cooling mechanisms 4A and 4B. The radioisotope manufacturing apparatus includes the target accommodating device 10 and an accelerator, not shown. As an accelerator, for example, a cyclotron or the like is used, which generates a charged particle beam (hereinafter, referred to as a "particle beam"), and irradiates the target container 10 with the generated particle beam B along an irradiation axis RL. Examples of the particle beam B irradiated to the target accommodating apparatus 10 include a proton beam, a deuteron beam, and the like. The target accommodating device 10 is attached to an exit from which the particle beam B of the accelerator is extracted via a manifold (not shown) disposed between the target accommodating device and the accelerator. In the following description, the direction in which the irradiation axis RL extends may be referred to as the longitudinal direction D1 of the target accommodating apparatus 10. The side irradiated with the particle beam B in the longitudinal direction D1 (the upstream side in the traveling direction of the particle beam) may be referred to as the front side of the target container 10, and the opposite side may be referred to as the rear side of the target container 10. A direction perpendicular to the longitudinal direction D1 and the vertical direction of the target container 10 may be referred to as a width direction D2.
In describing the positional relationship, terms such as "outside" and "inside" with reference to the irradiation axis RL may be used. The outer side with respect to the irradiation axis RL is the side distant from the irradiation axis RL in the direction orthogonal to the irradiation axis RL. The outer side with respect to the irradiation axis RL may be simply referred to as "outer peripheral side". The inner side with respect to the irradiation axis RL is a side closer to the irradiation axis RL in a direction orthogonal to the irradiation axis RL. The inner side with respect to the irradiation axis RL is sometimes simply referred to as "inner peripheral side".
The target accommodating device 10 has, for example, a cylindrical outer shape. The target accommodating device 10 includes: a target container 12 for mainly forming the accommodating portion 3; a cooling mechanism forming part 13 for mainly forming the cooling mechanism 4A; and an inner ring 14 and an outer ring 15 for mainly forming the cooling mechanism 4B. The front flange 11, the target container 12, and the cooling mechanism forming member 13 are made of a metal block. The front flange 11, the target container 12, and the cooling mechanism forming member 13 are sequentially overlapped from the front side toward the rear side in the longitudinal direction D1.
The foil 2 is a member that partitions the housing portion 3 on the front side. The foil 2 is arranged to the target container 12. The foil 2 allows the particle beam B to pass through, and on the other hand, blocks the fluid, such as the liquid target 101, He gas, etc., from passing through. Therefore, the particle beam B is irradiated to the foil 2, and then irradiated to the liquid target 101 through the foil 2. For example, He gas is blown onto the front surface of the foil 2 to be used as a cooling gas for the foil 2. The foil 2 is a thin foil made of a metal such as Ti or an alloy, and has a thickness of about 10 to 50 μm. The foil 2 is arranged to cover at least the entire area of the receiving portion 3.
The containing section 3 is a portion that contains the liquid target 101. The housing portion 3 is constituted by a space surrounded by the recess 22 formed in the target container 12, the cavity 25 formed in the target container 12 and communicating with the recess 22, and the foil 2. The target container 12 can be formed of Nb, for example. Is enclosed in the accommodating part 3 18 O (target water) as the liquid target 101. The recess 22 is recessed from the front surface of the target container 12, for example, the fixing surface 12a of the fixing foil 2, toward the rear side in the longitudinal direction D1. The recess 22 has a bottom surface 22a and a peripheral surface 22b extending from the outer peripheral edge of the bottom surface 22a toward the front side in the longitudinal direction D1. The housing portion 3 is circular when viewed from the longitudinal direction D1 (refer to fig. 4). The cavity portion 25 is a space extending obliquely upward from the upper end of the recess 22. The cavity portion 25 is inclined to extend upward toward the rear side in the length direction D1. The cavity 25 communicates with the upper end of the recess 22. The cavity portion 25 has a fan shape when viewed from the longitudinal direction D1 (refer to fig. 5).
The target container 12 is formed with a gas introduction hole (not shown) for introducing an inert gas (e.g., He gas) into the housing portion 3. The target container 12 is provided with a flow hole 26 (see fig. 4), and the flow hole 26 is used when the liquid target 101 is filled in the storage unit 3 and when the liquid target 101 in the storage unit 3 is discharged.
The housing portion 3 has: a 1 st accommodating portion E1 accommodating the liquid target 101; and a 2 nd accommodating part E2 located above the 1 st accommodating part E1 and receiving a gas target formed by evaporating the boiling liquid target 101. The 2 nd accommodating part E2 is continuously formed at the upper side of the 1 st accommodating part E1. Here, the space formed by the recess 22 corresponds to the 1 st accommodation part E1, and the space formed by the cavity 25 corresponds to the 2 nd accommodation part E2.
The cooling mechanism 4A cools the housing portion 3 with a cooling medium on the side opposite to the irradiation direction of the particle beam B irradiated to the liquid target 101 (i.e., the rear surface side). The cooling mechanism 4A includes a 1 st cooling unit 30A that cools the 1 st accommodation portion E1 and a 2 nd cooling unit 30B that cools the 2 nd accommodation portion E2. The 1 st cooling unit 30A includes a nozzle portion 32A disposed in the 1 st internal space 31A (1 st flow path). The 2 nd cooling unit 30B includes a nozzle 32B disposed in the 2 nd internal space 31B (1 st flow path).
The 1 st internal space 31A and the 2 nd internal space 31B are spaces for flowing a cooling medium inside. The 1 st internal space 31A and the 2 nd internal space 31B are formed by a space between the target container 12 and the cooling mechanism forming member 13 by attaching the cooling mechanism forming member 13 to the recess 30 on the rear side of the target container 12. The 1 st inner space 31A is formed at the rear side in the length direction D1 with respect to the 1 st accommodating part E1 of the accommodating part 3. The 2 nd inner space 31B is formed at the rear side in the length direction D1 with respect to the 2 nd accommodating part E2 of the accommodating part 3. That is, the 2 nd internal space 31B is provided above the 1 st internal space 31A. A heat transfer wall portion 34A is provided between the internal space 31A and the 1 st accommodation portion E1. A heat transfer wall portion 34B is provided between the internal space 31B and the 2 nd accommodating portion E2. And, the 1 st internal space 31A and the 2 nd internal space 31B are partitioned from each other by the partition plate 36.
The 1 st nozzle portion 32A is a member that injects the cooling medium to the heat transfer wall portion 34A between it and the 1 st accommodating portion E1. The 1 st nozzle portion 32A jets the cooling medium perpendicularly to the heat transfer wall portion 34. The 1 st nozzle portion 32A is separated from the heat transfer wall portion 34. The 2 nd nozzle portion 32B is a member that injects the cooling medium to the heat transfer wall portion 34B between it and the 2 nd accommodating portion E2. The 2 nd nozzle portion 32B jets the cooling medium perpendicularly with respect to the heat transfer wall portion 34B. The 2 nd nozzle portion 32B is separated from the heat transfer wall portion 34B.
Next, the cooling mechanism 4B will be explained. First, the inner ring 14 is attached to the target container 12 so as to surround the accommodating portion 3 around the irradiation axis RL. Therefore, in the target container 12, an annular recess 40 (particularly, refer to fig. 4) is formed so that the inner ring 14 can be attached from the outer peripheral side. The inner ring 14 has a half-divided structure of semicircular members 14A and 14B, and is attached to the recess 40 from the outer peripheral side (see fig. 5). The inner ring 14 has an annular shape with a substantially quadrangular cross section. However, the inner diameter of the inner ring 14 is locally reduced at a portion corresponding to the cavity portion 25 (see fig. 5), and an inclined surface 14b is formed on the inner circumferential side (see fig. 4). A support surface 40a is formed in the target container 12 so as to face the inner ring 14 on the rear side. The outer ring 15 is attached to the support surface 40a so as to support the inner ring 14 attached to the recess 40 from the outer peripheral side.
The target container 12 has a wall portion facing the inner peripheral surface 14a of the inner ring 14 at the position of the recess 22 of the accommodating portion 3. This wall portion constitutes the heat transfer wall portion 41 of the 1 st accommodation portion E1 formed around the irradiation axis RL. The heat transfer wall 41 is formed as a cylindrical thin portion. The target container 12 has a wall portion facing the inclined surface 14b of the inner ring 14 at the position of the cavity portion 25. This wall portion constitutes the heat transfer wall portion 42 of the 2 nd accommodating portion E2 formed around the irradiation axis RL. The heat transfer wall portion 41 is formed to be thin at a position where the outer peripheral side faces the heat transfer wall portion 34B. The heat transfer wall 42 is formed in a fan shape when viewed from the longitudinal direction, and the heat transfer wall 41 is formed over the entire circumference of the portion other than the heat transfer wall 42 (see fig. 5). Further, a step wall portion 44 (see fig. 5) rising from the support surface 40a toward the heat transfer wall portion 42 is formed between the heat transfer wall portion 41 and the heat transfer wall portion 42.
A cooling flow path 46 (2 nd flow path) for flowing a cooling medium is formed between the heat transfer wall portion 41 surrounding the 1 st accommodation portion E1 and the inner peripheral surface 14a of the inner ring 14. The 1 st accommodating portion E1 of the accommodating portion 3 is provided at a position further inside than the heat transfer wall portion 41 with respect to the irradiation axis RL. The cooling channel 46 is provided outside the heat transfer wall 41 with respect to the irradiation axis RL. Therefore, the cooling flow path 46 can circulate the cooling medium so as to cool the 1 st containing portion E1 of the containing section 3 from a position further outside than the 1 st containing portion E1 of the containing section 3 with respect to the irradiation axis RL via the heat transfer wall portion 41 provided around the irradiation axis RL with respect to the containing section 3. The cooling flow path 46 is capable of flowing a cooling medium so as to cool the 1 st accommodating portion E1 of the accommodating portion 3 from the outer peripheral side of the heat transfer wall portion 41 provided around the irradiation axis RL with respect to the accommodating portion 3, via the heat transfer wall portion 41. The cooling flow path 46 can cool the 1 st containing portion E1 capable of containing the liquid target 101 in the containing section 3. With this configuration, the cooling passage 46 can allow the cooling medium to flow therethrough so as to discharge heat from the 1 st housing portion E1 of the housing portion 3 from the inside to the outside with respect to the irradiation axis RL via the heat transfer wall portion 41.
A cooling flow path 48 (2 nd flow path) for flowing the cooling medium is formed between the heat transfer wall portion 42 surrounding the 2 nd accommodating portion E2 and the inclined surface 14b of the inner ring 14. The 2 nd accommodating portion E2 of the accommodating portion 3 is provided at a position further inside than the heat transfer wall portion 42 with respect to the irradiation axis RL. The cooling channel 48 is provided outside the heat transfer wall 42 with respect to the irradiation axis RL. Therefore, the cooling flow path 48 can be flowed through by the cooling medium to cool the 2 nd accommodating part E2 of the accommodating section 3 from a position further outside than the 2 nd accommodating part E2 of the accommodating section 3 with respect to the irradiation axis RL via the heat transfer wall portion 42 provided around the irradiation axis RL with respect to the accommodating section 3. The cooling flow path 48 is capable of flowing a cooling medium so as to cool the 2 nd accommodating portion E2 of the accommodating portion 3 from the outer peripheral side of the heat transfer wall portion 42 provided around the irradiation axis RL with respect to the accommodating portion 3 via the heat transfer wall portion 42. The cooling flow path 48 can cool the 2 nd accommodating portion E2 in the accommodating portion 3 that can accommodate the gas target 102. The cooling flow path 48 can cool the 2 nd accommodating part E2 of the accommodating section 3 from the side opposite to the internal space 31B with respect to the irradiation axis RL through the 2 nd accommodating part E2. With this configuration, the cooling flow path 48 allows the cooling medium to flow therethrough so as to discharge heat from the 2 nd housing portion E2 of the housing portion 3 from the inside to the outside with respect to the irradiation axis RL via the heat transfer wall portion 42. In addition, the 2 nd internal space 31B can be flowed through by the cooling medium to cool the 2 nd accommodating part E2 of the accommodating part 3 from a position further inside than the 2 nd accommodating part E2 of the accommodating part 3 with respect to the irradiation axis RL via the heat transfer wall part 34B provided around the irradiation axis RL with respect to the accommodating part 3. The 2 nd internal space 31B can flow the cooling medium so as to discharge heat from the 2 nd accommodating portion E2 of the accommodating portion 3 from the outside to the inside with respect to the irradiation axis RL via the heat transfer wall portion 34B.
Further, a flow passage 47 communicating with the cooling flow passage 46 is formed between the support surface 40a and the inner ring 14. The flow path 47 communicates with a supply pipe 51 and a discharge pipe 52 of the cooling medium. Therefore, the flow path 47 supplies and recovers the cooling medium to and from the cooling flow paths 46 and 48.
Next, the flow of the cooling medium to the cooling passages 46 and 48 will be described with reference to fig. 3 and 5. The supply pipe 51 and the discharge pipe 52 are provided in the vicinity of the lower end of the support surface 40 a. A partition plate 54 for blocking the flow of the cooling medium is provided between the supply pipe 51 and the discharge pipe 52. First, the cooling medium supplied from the supply pipe 51 flows through the flow path 47(F1) and is supplied to the cooling flow path 46. Thereby, a part of the cooling medium flows through the cooling passage 46 (F2). In the stepped wall portion 44, the cooling medium flows over the stepped wall portion 44 (F3) and is supplied to the cooling flow path 48. Thereby, the cooling medium flows through the cooling passage 48 (F4). In the next step wall portion 44, the cooling medium flows down along the step wall portion 44 (F5) and is supplied to the cooling flow paths 46 and 47. Thereby, the cooling medium flows through the cooling passage 46(F6) and flows through the cooling passage 47 (F7).
Next, the operational effects of the RI manufacturing apparatus 1 and the target accommodating apparatus 10 according to the present embodiment will be described.
The RI manufacturing apparatus 1 includes internal spaces 31A and 31B, and the internal spaces 31A and 31B allow a cooling medium to flow therethrough so as to cool the housing unit 3 from one side (rear side) with respect to the irradiation axis RL of the particle beam B. Thus, the target in the housing portion 3 can be cooled from the side opposite to the irradiation axis RL by flowing the cooling medium through the internal spaces 31A and 31B. The RI manufacturing apparatus 1 further includes cooling flow paths 46 and 48, and the cooling flow paths 46 and 48 allow a cooling medium to flow therethrough so as to cool the housing unit 3 from a position outside the housing unit 3 with respect to the irradiation axis RL via the heat transfer wall portions 41 and 42 provided around the irradiation axis RL with respect to the housing unit 3. At this time, the heat is discharged from the housing portion 3 from the inside to the outside with respect to the irradiation axis RL through the heat transfer wall portions 41 and 42 surrounding the irradiation axis RL by flowing the cooling medium through the cooling flow paths 46 and 48, whereby the target in the housing portion 3 can be cooled. In this way, the targets can be cooled from different directions by the internal spaces 31A and 31B and the cooling channels 46 and 48. Therefore, the efficiency of cooling the target can be improved, and thus the efficiency of nuclear reaction of the target can be improved.
The cooling flow path 46 may be configured to cool the 1 st containing portion E1 capable of containing the liquid target 101 in the containing section 3. At this time, the cooling channel 46 cools the liquid target 101 that has become hot due to the irradiation with the particle beam B, and thereby evaporation of the liquid target 101 can be suppressed. Therefore, the efficiency of the nuclear reaction of the liquid target 101 can be improved.
The cooling flow path 48 may be configured to cool the 2 nd accommodating portion E2 in the accommodating portion 3 that can accommodate the gas target 102. At this time, the cooling channel 48 can liquefy the gas target 102 by cooling it. Therefore, the efficiency of the nuclear reaction can be improved by increasing the amount of the liquid target 101.
The housing portion 3 may have: a 1 st accommodating portion E1 capable of accommodating the liquid target 101; and a 2 nd accommodating portion E2 communicating with the 1 st accommodating portion E1 and capable of accommodating the gas target 102, and the cooling passage 48 is capable of cooling the accommodating portion 3 from the side opposite to the internal space 31B with respect to the irradiation axis RL through the 2 nd accommodating portion E2. At this time, the liquid target 101 in the 1 st accommodation part E1 is evaporated by the irradiated particle beam B, and is stored as the gas target 102 in the 2 nd accommodation part E2. In contrast, the internal space 31B and the cooling channel 48 can cool the gas target 102 from both sides with respect to the irradiation axis RL. Thereby, the gas target 102 can be liquefied by cooling and returned to the 1 st containing portion E1 as the liquid target 101. Therefore, the efficiency of the nuclear reaction can be improved by increasing the amount of the liquid target 101.
The target accommodating device 10 includes internal spaces 31A and 31B, and the internal spaces 31A and 31B allow a cooling medium to flow therethrough so as to cool the accommodating portion 3 from one side (rear side) with respect to the irradiation axis RL of the particle beam B. Thus, the target in the housing portion 3 can be cooled from the side opposite to the irradiation axis RL by flowing the cooling medium through the internal spaces 31A and 31B. The target accommodating device 10 includes cooling flow paths 46 and 48, and the cooling flow paths 46 and 48 allow a cooling medium to flow therethrough so as to cool the accommodating portion 3 from a position outside the accommodating portion 3 with respect to the irradiation axis RL via the heat transfer wall portions 41 and 42 provided around the irradiation axis RL with respect to the accommodating portion 3. At this time, by flowing the cooling medium through the cooling channels 46 and 48, the heat can be exhausted from the housing portion 3 from the inside to the outside with respect to the irradiation axis RL through the heat transfer wall portions 41 and 42 surrounding the irradiation axis RL, thereby cooling the target in the housing portion 3. In this way, the targets can be cooled from different directions by the internal spaces 31A and 31B and the cooling channels 46 and 48. Therefore, the efficiency of cooling the target can be improved, and thus the efficiency of nuclear reaction of the target can be improved. Therefore, the cooling efficiency of the target can be improved.
The present invention is not limited to the above embodiments.
For example, a member that blocks the flow of the cooling medium may be provided in the cooling passages 46 and 48. At this time, the member blocks the flow of the cooling medium in the cooling passages 46 and 48 to change the laminar flow to the turbulent flow, thereby improving the cooling efficiency. For example, as shown in fig. 6, a member 60 that blocks the flow of the cooling medium is provided on at least one of the inner circumferential surface 14a of the inner ring 14 and the heat transfer wall portion 41. At this time, the slit is formed in the cooling passage 46 by the member 60. The flow is blocked by such a slit structure, and the cooling medium becomes turbulent.
The specific configurations of the RI manufacturing apparatus and the target accommodating apparatus of the present invention are not limited to the above-described embodiments.
At least one of the cooling channels 46 and 48 may be provided, and the other may be omitted.

Claims (6)

1. An RI production apparatus that produces a radioisotope by a nuclear reaction of a target irradiated with a particle beam, the RI production apparatus comprising:
an accommodating unit for accommodating the target at an irradiation position of the particle beam;
a 1 st flow path through which a cooling medium can flow so as to cool the housing section from one side with respect to an irradiation axis of the particle beam; and
and a 2 nd flow path through which a cooling medium can flow so as to cool the housing section from a position outside the housing section with respect to the irradiation axis via at least a part of a wall section provided around the irradiation axis with respect to the housing section.
2. The RI manufacturing apparatus according to claim 1,
the 2 nd flow path can cool a portion capable of accommodating the liquid target in the accommodating portion.
3. The RI manufacturing apparatus according to claim 1 or 2, wherein,
the 2 nd flow path can cool a portion of the housing portion capable of housing the gas target.
4. The RI manufacturing apparatus according to any one of claims 1 to 3, wherein,
the accommodating portion has: a 1 st containing portion capable of containing a liquid target; and a 2 nd accommodating part communicating with the 1 st accommodating part and capable of accommodating a gas target,
the 2 nd flow path can cool the housing section from the side opposite to the 1 st flow path with respect to the irradiation axis through the 2 nd housing section.
5. The RI manufacturing apparatus according to any one of claims 1 to 4,
the 2 nd flow path is provided with a member that blocks the flow of the cooling medium.
6. A target accommodating apparatus that accommodates a target capable of producing a radioisotope by a nuclear reaction by being irradiated with a particle beam, the target accommodating apparatus comprising:
an accommodating portion accommodating the target;
a 1 st flow path through which a cooling medium can flow so as to cool the housing section from a side opposite to an irradiation axis of the particle beam when the target is irradiated with the particle beam; and
and a 2 nd flow path through which a cooling medium can flow so as to cool the housing section from a position outside the housing section with respect to the irradiation axis via at least a part of a wall section provided around the irradiation axis with respect to the housing section.
CN202210318662.8A 2021-03-29 2022-03-29 RI manufacturing apparatus and target accommodating apparatus Pending CN115132394A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021055409A JP2022152583A (en) 2021-03-29 2021-03-29 Ri production apparatus and target storage device
JP2021-055409 2021-03-29

Publications (1)

Publication Number Publication Date
CN115132394A true CN115132394A (en) 2022-09-30

Family

ID=83376561

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210318662.8A Pending CN115132394A (en) 2021-03-29 2022-03-29 RI manufacturing apparatus and target accommodating apparatus

Country Status (4)

Country Link
JP (1) JP2022152583A (en)
KR (1) KR20220135192A (en)
CN (1) CN115132394A (en)
TW (1) TWI818484B (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280505A (en) * 1991-05-03 1994-01-18 Science Research Laboratory, Inc. Method and apparatus for generating isotopes
US9336915B2 (en) * 2011-06-17 2016-05-10 General Electric Company Target apparatus and isotope production systems and methods using the same
JP2013246131A (en) 2012-05-29 2013-12-09 Sumitomo Heavy Ind Ltd Ri manufacturing apparatus
JP2018013465A (en) * 2016-07-08 2018-01-25 日本メジフィジックス株式会社 Radioactive nuclide production device, target device and manufacturing method of radioactive medicine
JP7183098B2 (en) * 2019-03-27 2022-12-05 住友重機械工業株式会社 Target device
CN110828021A (en) * 2019-11-04 2020-02-21 中国原子能科学研究院 Water cooling mechanism for medical isotope production target

Also Published As

Publication number Publication date
TWI818484B (en) 2023-10-11
JP2022152583A (en) 2022-10-12
TW202238625A (en) 2022-10-01
KR20220135192A (en) 2022-10-06

Similar Documents

Publication Publication Date Title
JP4541445B2 (en) Radioisotope production apparatus and radioisotope production method
JP6276745B2 (en) Self-shielding targets for isotope production systems
US20160141062A1 (en) Target body for an isotope production system and method of using the same
JP6791996B2 (en) Target assembly and isotope generation system with grid portion
RU2769259C2 (en) Target assembly and nuclide production system
JP2013246131A (en) Ri manufacturing apparatus
US8670513B2 (en) Particle beam target with improved heat transfer and related apparatus and methods
KR101366689B1 (en) F-18 radio isotopes water target apparatus for improving cooling performance??with internal flow channel using thermosiphon
CN115132394A (en) RI manufacturing apparatus and target accommodating apparatus
US10354771B2 (en) Isotope production system having a target assembly with a graphene target sheet
JP2018013465A (en) Radioactive nuclide production device, target device and manufacturing method of radioactive medicine
JP7183098B2 (en) Target device
JP7445491B2 (en) target device
JP4994589B2 (en) Target for radioisotope production
JP6730874B2 (en) Radionuclide manufacturing apparatus, target apparatus and method for manufacturing radiopharmaceutical
EP2425686B1 (en) Particle beam target with improved heat transfer and related method
Abubaker et al. Cyclotron for PET: System Upgrade after 13 Years of Service
KR102044776B1 (en) Target for isotope production including easy replacement structure for window foil

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40081556

Country of ref document: HK