CN115089643A - Medical rectal cancer ointment and preparation method thereof - Google Patents
Medical rectal cancer ointment and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medical rectal cancer ointment, which relates to the field of traditional Chinese medicines and aims to solve the problems that the self-medication cannot meet the medication standard and people need to take auxiliary medicines in the prior art; the Chinese angelica, the golden cypress, the astragalus, the motherwort, the white paeony root, the prepared rehmannia root, the poria cocos and the irkutsk anemone rhizome are used and are subjected to compatibility treatment according to monarch, minister, assistant and guide to treat intestinal cancer, anal fissure and haemorrhoids, the purposes of no operation and no operation can be achieved, the prepared medicine can directly reach a focus, and local necrotic tissues can be separated and discharged out of a body.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a medical rectal cancer ointment and a preparation method thereof.
Background
Rectal cancer refers to cancer from the dentate line to the junction of the rectosigmoid colon, and is one of the most common malignancies of the digestive tract. Rectal cancer is low in location and is easily diagnosed by digital rectal examination and sigmoidoscope. But the position of the pelvic cavity is deep, so the anatomical relationship is complex, the operation is not easy to be thorough, and the postoperative recurrence rate is high. The middle and lower rectal cancer is close to the anal sphincter, and the difficulty in retaining the anus and the function of the anus during the operation is a difficult problem of the operation and is also a disease which is most controversial on the operation method.
Hemorrhoid, also known as hemorrhoid, is the most common clinical anal disease, and is the pathological hypertrophy of the anal pad at the lower end of the rectum. Hemorrhoids can be classified into internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids, depending on the location of the affected part. Internal hemorrhoids are currently believed to be pathological changes or displacements in the supporting structure of the anal pad (anal canal vascular pad), vascular plexus and arteriovenous anastomotic support. External hemorrhoids are pathological dilations or thromboses of the subcutaneous vascular plexus distal to the dentate line. The mixed hemorrhoid is a mixture of internal hemorrhoid and external hemorrhoid.
The causes of hemorrhoids are mainly the following directions:
theory of varicose veins: the venous plexus is the main structure forming the anal pad, and the formation of hemorrhoids is necessarily connected with the pathological expansion and thrombosis of the venous plexus. Anatomically, the portal system and its branch rectal veins are devoid of venous valves; the wall of the upper and lower rectum vena plexus is thin and the position is shallow; the tissues under the rectal mucosa at the end relax, and these factors all tend to cause blood stasis and venous distension. In addition, as the rectal anal canal is positioned at the lowest part of the abdominal cavity, the rectal venous reflux can be blocked by various factors, such as long-term sitting and standing, constipation, pregnancy, prostatic hypertrophy, huge pelvic tumors and the like. Are at present controversial.
Anal pad lower theory: the anal pad plays a role in closing the anal canal and controlling defecation. Under normal conditions, the anal pad is loosely attached to the muscular wall of the anal canal; when in defecation, the excrement is pushed downwards under the downward pressure, and is retracted into the anal canal under the self-contraction action after defecation. After the elastic retraction ability is weakened, the anal pad is congested and moves downwards to form hemorrhoids. Western medicine mainstream supports the theory of anal cushion moving downwards.
The existing hemorrhoid surgery needs an operation, which wastes time and labor, and the self-administration can not reach the administration standard, and people need to take medicine in an auxiliary way.
Disclosure of Invention
In view of the problems in the prior art, the invention discloses a medical rectal cancer ointment, which adopts the technical scheme that the ointment comprises the following components:
angelica sinensis, phellodendron amurense, astragalus membranaceus, motherwort, radix paeoniae alba, prepared rehmannia root, poria cocos and irkutsk anemone rhizome.
The rectal cancer ointment can be supported by the components, and the medicine can directly reach the focus.
As a preferred technical scheme of the invention, the weight ratio of each component is as follows:
5-12 parts of angelica sinensis, 10-15 parts of phellodendron, 3-6 parts of astragalus membranaceus, 2-4 parts of motherwort, 5-7 parts of radix paeoniae alba, 1-2 parts of prepared rehmannia root, 1-2 parts of poria cocos and 2-4 parts of irkutsk anemone rhizome.
The invention also discloses a preparation method of the medical rectal cancer ointment, and the adopted technical scheme is that the preparation method comprises the following steps:
step 1, mixing and crushing angelica sinensis, phellodendron amurense, astragalus membranaceus, motherwort and radix paeoniae alba according to parts to obtain medicinal powder A; the components are crushed to facilitate the subsequent extraction of the liquid medicine;
step 2, sieving the medicinal powder A obtained in the step 1, further crushing the sieved large-particle medicinal granules, and mixing the crushed medicinal granules with the sieved medicinal powder to obtain medicinal powder A; the medicine powder A has no large granule;
step 3, adding a 95% ethanol solution into the medicine powder A, soaking and filtering to obtain a medicine liquid A; the organic extract can be extracted from the powder A by ethanol soaking;
step 4, mixing and crushing prepared rehmannia root, tuckahoe and irkutsk anemone rhizome according to parts, and obtaining medicinal powder B; the crushed medicine enables the subsequent extraction operation to be smoother;
step 5, sieving the medicinal powder B obtained in the step 4, further crushing the sieved large-particle medicinal granules, and mixing the crushed medicinal granules with the sieved medicinal powder to obtain medicinal powder B;
step 6, adding a 95% ethanol solution into the medicine powder B, soaking and filtering to obtain a medicine liquid B; extracting the extract from the medicine by ethanol soaking;
step 7, mixing the liquid medicine A obtained in the step 3 and the liquid medicine B obtained in the step 6 to obtain mixed liquid medicine; the subsequent paste preparation operation is convenient;
and 8, decocting and preparing the mixed liquid medicine obtained in the step 7 into paste to volatilize alcohol and water, and adding proper water according to needs in the decocting process to adjust the viscosity.
In the step 2, a 200-mesh sieve is used for sieving to obtain large-particle medicine particles.
As a preferred technical scheme of the invention, in the step 5, a 300-mesh sieve is used for sieving to obtain large-particle medicine particles.
In the step 3 and the step 6, a stirring device is used for stirring during the soaking process, the stirring speed is 300r/min, the stirring operation can ensure that the alcohol is more fully and uniformly contacted with the medicine powder, and the extraction effect is better.
The invention has the beneficial effects that: according to the invention, angelica sinensis, phellodendron amurense, astragalus membranaceus, motherwort, radix paeoniae alba, prepared rehmannia root, poria cocos and irkutsk anemone rhizome are used, and the compatibility is carried out according to monarch, minister, assistant and guide to treat intestinal cancer, anal fissure and haemorrhoids, so that operation can be avoided, the prepared medicine can directly reach a focus, and local necrotic tissues can be separated and discharged out of a body.
Detailed Description
Example 1
In this embodiment, a medical ointment for rectal cancer comprises the following components:
5 parts of angelica sinensis, 10 parts of phellodendron, 3 parts of astragalus membranaceus, 2 parts of motherwort, 5 parts of radix paeoniae alba, 1 part of prepared rehmannia root, 1 part of poria cocos and 2 parts of irkutsk anemone rhizome.
The angelica has the effect of enriching the blood; promoting blood circulation; regulating menstruation and relieving pain; moistening dryness and smoothing intestine. The main symptoms are blood deficiency; menoxenia; amenorrhea; dysmenorrhea; the symptoms are accumulated; (ii) metrorrhagia and metrostaxis; abdominal pain due to deficiency-cold; flaccidity and paralysis; numbness of the skin; intestinal dryness and difficult defecation; severe dysentery with diarrhea; carbuncle, deep-rooted carbuncle, sore and ulcer; injury from the fall. The pharmacological action is as follows: has antithrombotic, blood circulation improving, coronary circulation improving, antiinflammatory, pain relieving, blood sugar lowering, and blood tonifying effects.
Cortex Phellodendri has effects of clearing heat, eliminating dampness, purging pathogenic fire, removing steam, removing toxic substance, and treating sore; can be used for treating dysentery due to damp-heat pathogen, jaundice, dark urine, leukorrhagia, pudendal pruritus, pyretic stranguria, pain, tinea pedis, atrophic debility cramped, hectic fever, night sweat, nocturnal emission, pyocutaneous disease, toxic swelling, eczema, and eczema. Salted cortex phellodendri is used for nourishing yin and reducing internal heat. Can be used for treating hyperactivity of fire due to yin deficiency, night sweat and steaming bone.
The astragalus root is matched with the angelica: astragalus membranaceus tonifies qi of spleen and lung to benefit the source of blood; dang Gui nourishes heart and liver blood to nourish blood and regulate nutrient. The two medicines are combined to enhance the functions of tonifying qi and generating blood. It is suitable for fatigue, internal injury, muscle heat, flushed face, polydipsia, pulse deficiency, asthenia, pyocutaneous disease, fever due to blood deficiency, and deficiency of qi and blood.
The motherwort has the functions of promoting blood circulation to restore menstrual flow, inducing diuresis to reduce edema and clearing away heat and toxic materials. Can be used for treating menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema, oliguria, pyocutaneous disease, and toxic swelling.
White peony root, radix Paeoniae alba is pungent and bitter in flavor; has little toxicity; has the effects of warming yang, eliminating dampness, tonifying deficiency, strengthening spleen and stomach, etc. The radix Paeoniae alba is used for treating rheumatism psychroalgia, rheumatic arthritis, lumbar muscle strain, asthenia, convulsion of limbs, chronic infantile convulsion, and dog bite; nourishing blood, regulating menstruation, softening liver, relieving pain, astringing yin, arresting sweating, and suppressing liver yang.
Prepared rehmannia root, radix rehmanniae Praeparata has the effects of nourishing yin and blood, and replenishing essence and marrow. Can be used for treating deficiency of liver-yin and kidney-yin, soreness of waist and knees, hectic fever, night sweat, nocturnal emission, internal heat, diabetes, blood deficiency, sallow complexion, cardiopalmus, severe palpitation, menoxenia, metrorrhagia, metrostaxis, hemorrhage, giddiness, tinnitus, and early white beard and hair.
Poria is used for treating edema, oliguria, phlegm-fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Rhizoma anemones Altaicae has effects of inducing resuscitation, eliminating phlegm, activating spleen, and tranquilizing mind. Can be used for treating fever unconsciousness, epilepsy, tinnitus deafness, chest distress, abdominal distention, and anorexia; it is indicated for abscess, deep-rooted carbuncle, sore and tinea.
The preparation method of the medical rectal cancer paste comprises the following steps:
step 1, mixing and crushing angelica sinensis, phellodendron amurense, astragalus membranaceus, motherwort and radix paeoniae alba according to parts to obtain medicinal powder A;
step 2, screening the medicinal powder A obtained in the step 1 by using a 200-mesh sieve, further crushing large-particle medicinal granules obtained by screening, and mixing the crushed medicinal granules with the screened medicinal powder to obtain medicinal powder A;
step 3, adding 95% ethanol solution into the medicine powder A, stirring at the rotating speed of 300r/min for 20min, and filtering to obtain medicine liquid A;
step 4, mixing and crushing prepared rehmannia root, poria cocos and irkutsk anemone rhizome according to parts to obtain medicinal powder B;
step 5, sieving the medicinal powder B obtained in the step 4 by using a 300-mesh sieve, further crushing the sieved large-particle medicinal granules, and mixing the crushed medicinal granules with the sieved medicinal powder to obtain medicinal powder B;
step 6, adding a 95% ethanol solution into the medicine powder B, stirring at the rotating speed of 300r/min for 20min, and filtering to obtain a medicine liquid B;
step 7, mixing the liquid medicine A obtained in the step 3 and the liquid medicine B obtained in the step 6, and stirring for 5min at the rotating speed of 200r/min to obtain mixed liquid medicine;
and 8, decocting the mixed liquid medicine obtained in the step 7, and preparing paste.
Example 2
The difference between this example and example 1 is that the medical rectal cancer ointment comprises the following components: 12 parts of angelica sinensis, 15 parts of phellodendron, 6 parts of astragalus membranaceus, 4 parts of motherwort, 7 parts of radix paeoniae alba, 2 parts of prepared rehmannia root, 2 parts of poria cocos and 4 parts of irkutsk anemone rhizome.
Example 3
The difference between this example and example 1 is that the medical rectal cancer ointment comprises the following components: 8 parts of angelica sinensis, 12 parts of phellodendron, 4 parts of astragalus membranaceus, 3 parts of motherwort, 6 parts of radix paeoniae alba, 2 parts of prepared rehmannia root, 2 parts of poria cocos and 3 parts of irkutsk anemone rhizome.
Although the present invention has been described in detail with reference to the specific embodiments, the present invention is not limited to the above embodiments, and various changes and modifications without inventive changes may be made within the knowledge of those skilled in the art without departing from the spirit of the present invention.
Claims (6)
1. The medical paste for rectal cancer is characterized by comprising the following components:
chinese angelica, phellodendron, astragalus, motherwort, white paeony root, prepared rehmannia root, tuckahoe and irkutsk anemone rhizome.
2. The medical rectal cancer paste according to claim 1, wherein the weight ratio of each component is as follows:
5-12 parts of angelica sinensis, 10-15 parts of phellodendron, 3-6 parts of astragalus membranaceus, 2-4 parts of motherwort, 5-7 parts of radix paeoniae alba, 1-2 parts of prepared rehmannia root, 1-2 parts of poria cocos and 2-4 parts of irkutsk anemone rhizome.
3. A process for preparing a medical rectal cancer paste according to claim 1, comprising the steps of:
step 1, mixing and crushing angelica sinensis, phellodendron amurense, astragalus membranaceus, motherwort and radix paeoniae alba according to parts, and obtaining medicinal powder A;
step 2, sieving the medicinal powder A obtained in the step 1, further crushing the sieved large-particle medicinal granules, and mixing the crushed medicinal granules with the sieved medicinal powder to obtain medicinal powder A;
step 3, adding a 95% ethanol solution into the medicine powder A, soaking and filtering to obtain a medicine liquid A;
step 4, mixing and crushing prepared rehmannia root, tuckahoe and irkutsk anemone rhizome according to parts, and obtaining medicinal powder B;
step 5, sieving the medicinal powder B obtained in the step 4, further crushing the sieved large-particle medicinal granules, and mixing the crushed medicinal granules with the sieved medicinal powder to obtain medicinal powder B;
step 6, adding a 95% ethanol solution into the medicine powder B, soaking and filtering to obtain a medicine liquid B;
step 7, mixing the liquid medicine A obtained in the step 3 and the liquid medicine B obtained in the step 6 to obtain mixed liquid medicine;
and 8, decocting the mixed liquid medicine obtained in the step 7, and preparing paste.
4. The method for preparing a medical rectal cancer paste according to claim 3, wherein: in the step 2, sieving is carried out by using a 200-mesh sieve.
5. The method for preparing a medical paste for rectal cancer according to claim 3, characterized in that: in the step 5, a 300-mesh sieve is used for sieving.
6. The preparation method of the medical rectal ointment cancer agent according to claim 3, characterized in that: in the step 3 and the step 6, a stirring device is used for stirring in the soaking process, and the stirring speed is 300 r/min.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115813995A (en) * | 2022-12-14 | 2023-03-21 | 赵小聪 | A paste for treating diabetes and hypertension syndrome |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115813995A (en) * | 2022-12-14 | 2023-03-21 | 赵小聪 | A paste for treating diabetes and hypertension syndrome |
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Application publication date: 20220923 |