CN115040525A - Slimming fat solution and preparation method thereof - Google Patents
Slimming fat solution and preparation method thereof Download PDFInfo
- Publication number
- CN115040525A CN115040525A CN202210726164.7A CN202210726164A CN115040525A CN 115040525 A CN115040525 A CN 115040525A CN 202210726164 A CN202210726164 A CN 202210726164A CN 115040525 A CN115040525 A CN 115040525A
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- slimming
- chinese medicine
- traditional chinese
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Abstract
The invention provides a slimming fat-dissolving liquid and a preparation method thereof, wherein the slimming fat-dissolving liquid comprises the following raw materials in parts by weight: 300 parts of normal saline 200-one, 0.5-0.8 part of lidocaine, 3-5 parts of vitamin B complex, 1-3 parts of aminophylline, 0.5-1 part of triamcinolone acetonide or methylprednisolone and 0.6-1.2 parts of traditional Chinese medicine extract. The invention has the beneficial effects that: the slimming fat-dissolving liquid provided by the invention directly acts on subcutaneous fat, has an obvious effect, is small in side effect and quick to recover, and does not influence the normal life of a user. The weight-reducing fat-dissolving liquid has the advantages of light pain of patients in the injection process, convenient operation and incomparable advantages for the treatment of local obesity.
Description
Technical Field
The invention belongs to the technical field of medical cosmetology, and particularly relates to a slimming fat solution and a preparation method thereof.
Background
Obesity is a common group of metabolic disorders. Factors causing obesity include various factors such as irregular diet, abnormal work and rest, genetic, endocrine disorders, environmental factors, etc. The obesity not only affects the external appearance of people, especially women have higher requirements on the stature, but also causes some diseases, and medical researches prove that severe obesity can cause various damages to human bodies and can induce or aggravate diseases such as hypertension, hyperlipoidemia, coronary heart disease, diabetes, fatty liver, obstructive sleep dyspnea, arthritis, gout, osteoporosis, tumors and the like.
Currently, treatments for obesity include drug therapy and surgical therapy, in addition to diet control and physical activity enhancement. At present, orlistat, lorcaserin, L-carnitine and other weight-reducing medicines can be selected, but because of adverse drug reactions and drug resistance, how to safely and effectively apply the medicines in clinic still needs to be discussed, and meanwhile, the actual curative effect of many weight-reducing health-care products is mostly unsatisfactory. The fat dissolving needle produced by transportation means that a medicine is directly injected into a subcutaneous fat layer of a human body to dissolve fat, and the first fat dissolving injection kybella is approved by the Food and Drug Administration (FDA) in 2015 globally, so that the fat dissolving needle is suitable for adults with moderate and severe double-chin. At present, no relevant report of fat dissolving needle exists in China.
Disclosure of Invention
The invention aims to provide a safe and effective slimming fat solution and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a fat solution for reducing weight comprises the following raw materials in parts by weight: 300 parts of normal saline 200-one, 0.5-0.8 part of lidocaine, 3-5 parts of vitamin B complex, 1-3 parts of aminophylline, 0.5-1 part of triamcinolone acetonide or methylprednisolone and 0.6-1.2 parts of traditional Chinese medicine extract.
The slimming fat solution as a preferred embodiment comprises the following raw materials in parts by weight: 280 parts of normal saline 220-sodium bicarbonate, 0.6-0.7 part of lidocaine, 3-4 parts of vitamin B complex, 1-2 parts of aminophylline, 0.6-0.8 part of triamcinolone acetonide or methylprednisolone and 0.8-1.0 part of traditional Chinese medicine extract.
The slimming fat solution as a preferred embodiment comprises the following raw materials in parts by weight: 260 parts of normal saline, 0.6 part of lidocaine, 4 parts of vitamin B complex, 2 parts of aminophylline, 0.7 part of triamcinolone acetonide or methylprednisolone and 0.9 part of traditional Chinese medicine extract.
Lidocaine is a very good local anaesthetic, generally acting after one to three minutes of administration, with the effect remaining for one to three hours.
The vitamin B complex is a compound preparation, and each tablet contains 13 mg of main components of vitamin B, 21.5 mg of vitamin B, 60.2 mg of vitamin B, 10 mg of nicotinamide and 1 mg of calcium pantothenate. The auxiliary materials are as follows: starch, dextrin, calcium hydrogen phosphate and magnesium stearate. It can be used for preventing and treating malnutrition, anorexia, beriberi, and pellagra caused by vitamin B deficiency.
Aminophylline is a compound salt of theophylline and ethylenediamine, and the pharmacological action of aminophylline mainly comes from theophylline, and ethylenediamine enhances the water solubility of the aminophylline. It has the strongest relaxing effect on bronchial smooth muscle, can dilate bronchus, increase vital capacity, and has lasting effect, especially on spastic bronchus.
Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin disorders or to alleviate discomfort associated with oral ulcers.
As a preferred embodiment, the weight-reducing fat solution comprises the following raw materials in parts by weight: 5-15 parts of dendrobium officinale, 4-6 parts of cistanche, 3-8 parts of pseudo-ginseng, 8-12 parts of kudzuvine root, 4-6 parts of plantain seed and 3-5 parts of astragalus.
Dendrobium officinale is sweet in taste and slightly cold in nature, has the function of promoting the production of body fluid and is mainly characterized by promoting glandular secretion and organ movement.
Cistanche genus, Orobanchaceae family, warm in nature and sweet in flavor. Cistanche parasitism is a parasitic plant at the root of desert tree haloxylon ammodendron, and nutrients and water are absorbed from haloxylon ammodendron hosts, which is quite reputable as desert ginseng. Cistanchis herba has effects of invigorating kidney yang, replenishing essence and blood, and moistening intestinal tract, and can be used for treating essence and blood deficiency, lumbago, asthenia, tinnitus, blurred vision, and infertility due to cold womb. Besides, the cistanche deserticola has the functions of resisting aging, improving the immunity of the organism and promoting the synthesis of deoxyribonucleic acid.
Notoginseng radix is Araliaceae plant of Umbelliferae, has sweet, slightly bitter and warm nature, and has effects of removing blood stasis, stopping bleeding, subsiding swelling and relieving pain. In addition, Notoginseng radix has antiinflammatory and liver protecting effects, and Notoginseng radix saponin in Notoginseng radix has anti-tumor effect.
Radix Puerariae is dried root of Pueraria lobata Ohwi of Leguminosae, has sweet taste and cool nature, and has effects of relieving muscles and fever, promoting eruption, promoting fluid production to quench thirst, invigorating yang and relieving diarrhea; it is commonly used to treat exterior syndrome fever, stiffness and pain of neck and back, measles without adequate eruption, fever thirst, yin deficiency with thirst, heat diarrhea and dysentery, spleen deficiency with diarrhea, etc.
Semen plantaginis is dry mature seed of Plantago asiatica or Plantago depressa of Plantaginaceae, and has effects of promoting diuresis, clearing heat, improving eyesight, and eliminating phlegm. It is commonly used to treat urinary obstruction, stranguria with turbid urine, leukorrhagia, hematuria, summer-heat-dampness dysentery, cough with excessive phlegm, damp arthralgia, conjunctival congestion and nebula.
Radix astragali is root of Astragalus membranaceus bge or Astragalus membranaceus bge of Leguminosae, and is one of the commonly used Chinese medicinal materials. Astragalus root has the effects of invigorating qi, consolidating superficial resistance, expelling pus, healing sore and promoting granulation, and is often used for treating qi deficiency, hypodynamia, sinking of middle-jiao energy, internal heat and diabetes. In addition, radix astragali can also enhance immunity, and has antitumor and osteoporosis resisting effects.
In a second aspect of the present application, there is provided a method for preparing a slimming solution, comprising the steps of:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, adding normal saline, lidocaine, vitamin B complex, aminophylline, triamcinolone acetonide or methylprednisolone into the sterilized traditional Chinese medicine extract, mixing and stirring uniformly, and sterilizing to obtain the slimming fat solution.
As a preferred embodiment, in the step (1), the specific operation of preparing the traditional Chinese medicine extract is as follows:
extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, freeze drying, and sterilizing to obtain the Chinese medicinal extract.
The above method for preparing a slimming solution, as a preferred embodiment, the freeze-drying is: freeze drying at-10 deg.C to-6 deg.C for 18-28 h.
In the above method for preparing a slimming solution, as a preferred embodiment, in step (2), the sterilization is ultrasonic sterilization.
As a preferable embodiment, the ultrasonic frequency of the ultrasonic sterilization is 15-30KHz, and the ultrasonic sterilization time is 10-50 min.
The invention has the beneficial effects that: the slimming fat-dissolving liquid provided by the invention directly acts on subcutaneous fat, has an obvious effect, is small in side effect and quick to recover, and does not influence the normal life of a user. The weight-reducing fat-dissolving liquid has the advantages of light pain of patients in the injection process, convenient operation and incomparable advantages for the treatment of local obesity.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
The weight reducing fat solution in the embodiment 1 comprises the following raw materials in parts by weight: 200 parts of normal saline, 0.5 part of lidocaine, 3 parts of vitamin B complex, 1 part of aminophylline, 0.5 part of triamcinolone acetonide and 0.6 part of traditional Chinese medicine extract;
the traditional Chinese medicine extract consists of the following raw materials in parts by weight: 5 parts of dendrobium officinale, 6 parts of cistanche, 8 parts of pseudo-ginseng, 8 parts of kudzu root, 4 parts of plantain seed and 3 parts of astragalus membranaceus.
The method for preparing the slimming solution of example 1 comprises the following steps:
(1) preparing a traditional Chinese medicine extract; extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, and freeze drying at-10 deg.C for 18 hr to obtain the Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract (ultrasonic sterilizing with 15KHz ultrasonic frequency for 15min), adding normal saline, lidocaine, vitamin B complex, aminophylline, and triamcinolone acetonide into the sterilized Chinese medicinal extract, mixing, stirring, and sterilizing with 15KHz ultrasonic frequency for 15min to obtain the slimming fat dissolving liquid.
Example 2
The weight reducing fat solution in the embodiment 2 comprises the following raw materials in parts by weight: 220 parts of normal saline, 0.6 part of lidocaine, 3 parts of vitamin B complex, 2 parts of aminophylline, 0.6 part of methylprednisolone and 0.8 part of traditional Chinese medicine extract;
the traditional Chinese medicine extract comprises the following raw materials in parts by weight: 10 parts of dendrobium officinale, 4 parts of cistanche, 5 parts of pseudo-ginseng, 8 parts of kudzu root, 5 parts of plantain seed and 3 parts of astragalus membranaceus.
The preparation method of the slimming solution of embodiment 2 comprises the following steps:
(1) preparing a traditional Chinese medicine extract; extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, and freeze drying at-8 deg.C for 20 hr to obtain the Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract (ultrasonic sterilizing with 20KHz ultrasonic frequency for 12min), adding normal saline, lidocaine, vitamin B complex, aminophylline, and methylprednisolone into the sterilized Chinese medicinal extract, mixing, stirring, and sterilizing with 20KHz ultrasonic frequency for 15min to obtain the slimming fat-dissolving liquid.
Example 3
The weight reducing fat solution in embodiment 3 comprises the following raw materials in parts by weight: 260 parts of normal saline, 0.6 part of lidocaine, 4 parts of vitamin B complex, 2 parts of aminophylline, 0.7 part of triamcinolone acetonide and 0.9 part of traditional Chinese medicine extract;
the traditional Chinese medicine extract comprises the following raw materials in parts by weight: 10 parts of dendrobium officinale, 5 parts of cistanche, 5 parts of pseudo-ginseng, 10 parts of kudzu root, 5 parts of plantain seed and 4 parts of astragalus membranaceus.
The method for preparing the slimming solution of example 3 comprises the following steps:
(1) preparing a traditional Chinese medicine extract; extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, and freeze drying at-6 deg.C for 20 hr to obtain the Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract (ultrasonic sterilizing with ultrasonic frequency of 25KHz for 12min), adding normal saline, lidocaine, vitamin B complex, aminophylline, and triamcinolone acetonide into the sterilized Chinese medicinal extract, mixing, stirring, and sterilizing with ultrasonic frequency of 25KHz for 12min to obtain the slimming fat dissolving liquid.
Example 4
The weight reducing fat solution in embodiment 4 comprises the following raw materials in parts by weight: 280 parts of normal saline, 0.7 part of lidocaine, 4 parts of vitamin B complex, 2 parts of aminophylline, 0.8 part of triamcinolone acetonide and 1.0 part of traditional Chinese medicine extract;
the traditional Chinese medicine extract comprises the following raw materials in parts by weight: 12 parts of dendrobium officinale, 5 parts of cistanche, 6 parts of pseudo-ginseng, 10 parts of kudzu root, 5 parts of plantain seed and 5 parts of astragalus membranaceus.
The method for preparing the slimming solution of example 4 comprises the following steps:
(1) preparing a traditional Chinese medicine extract; extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, and freeze drying at-10 deg.C for 18 hr to obtain the Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract (ultrasonic sterilizing with 28KHz for 12min), adding normal saline, lidocaine, vitamin B complex, aminophylline, and triamcinolone acetonide into the sterilized Chinese medicinal extract, mixing, stirring, and sterilizing with 28KHz ultrasonic for 15min to obtain the weight reducing fat dissolving liquid.
Example 5
The fat-reducing solution of embodiment 5 comprises the following raw materials in parts by weight: 300 parts of normal saline, 0.8 part of lidocaine, 3 parts of vitamin B complex, 3 parts of aminophylline, 1 part of triamcinolone acetonide and 1.2 parts of traditional Chinese medicine extract;
the traditional Chinese medicine extract comprises the following raw materials in parts by weight: 5 parts of dendrobium officinale, 4 parts of cistanche, 8 parts of pseudo-ginseng, 8 parts of kudzu root, 6 parts of plantain seed and 3 parts of astragalus membranaceus.
The method for preparing the slimming solution of example 5 comprises the following steps:
(1) preparing a traditional Chinese medicine extract; extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, and freeze drying at-10 deg.C for 28 hr to obtain the Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract (ultrasonic sterilizing with 30KHz ultrasonic frequency for 15min), adding normal saline, lidocaine, vitamin B complex, aminophylline, and triamcinolone acetonide into the sterilized Chinese medicinal extract, mixing, stirring, and sterilizing with 30KHz ultrasonic frequency for 15min to obtain the slimming fat dissolving liquid.
The application method of the slimming fat solution comprises the following steps: the range of fat accumulation is marked locally, and a needle point convenient for inserting the syringe is marked in the range, and the injection amount is about 20ml each time.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (9)
1. The weight-reducing fat solution is characterized by comprising the following raw materials in parts by weight: 300 parts of normal saline 200-one, 0.5-0.8 part of lidocaine, 3-5 parts of vitamin B complex, 1-3 parts of aminophylline, 0.5-1 part of triamcinolone acetonide or methylprednisolone and 0.6-1.2 parts of traditional Chinese medicine extract.
2. The slimming fat solution according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 280 parts of normal saline 220-sodium bicarbonate, 0.6-0.7 part of lidocaine, 3-4 parts of vitamin B complex, 1-2 parts of aminophylline, 0.6-0.8 part of triamcinolone acetonide or methylprednisolone and 0.8-1.0 part of traditional Chinese medicine extract.
3. The slimming fat solution according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 260 parts of normal saline, 0.6 part of lidocaine, 4 parts of vitamin B complex, 2 parts of aminophylline, 0.7 part of triamcinolone acetonide or methylprednisolone and 0.9 part of traditional Chinese medicine extract.
4. The slimming lipid solution according to claim 1, wherein the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 5-15 parts of dendrobium officinale, 4-6 parts of cistanche, 3-8 parts of pseudo-ginseng, 8-12 parts of kudzuvine root, 4-6 parts of plantain seed and 3-5 parts of astragalus.
5. A process for the preparation of a slimming solution according to any one of claims 1 to 4, characterized by comprising the following steps:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, adding normal saline, lidocaine, vitamin B complex, aminophylline, triamcinolone acetonide or methylprednisolone into the sterilized traditional Chinese medicine extract, mixing and stirring uniformly, and sterilizing to obtain the slimming fat solution.
6. The method for preparing a slimming solution according to claim 5, wherein the step (1) of preparing the herbal extract comprises the following specific steps:
extracting herba Dendrobii, Cistanchis herba, Notoginseng radix, radix Puerariae, semen plantaginis and radix astragali with ethanol under reflux, concentrating the extractive solution, freeze drying, and sterilizing to obtain the Chinese medicinal extract.
7. The method for preparing a slimming solution of claim 6, wherein the freeze-drying is: freeze drying at-10 deg.C to-6 deg.C for 18-28 h.
8. The method for preparing a slimming solution of claim 6, wherein in the step (2), the sterilization is ultrasonic sterilization.
9. The method for preparing a slimming solution according to claim 8, wherein the ultrasonic frequency of the ultrasonic sterilization is 15 to 30KHz, and the ultrasonic sterilization time is 10 to 50 min.
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CN102308988A (en) * | 2011-07-08 | 2012-01-11 | 云南普洱思松科贸有限责任公司 | Dendrobium health product having function of human body immunization enhancement |
KR20200144249A (en) * | 2019-06-18 | 2020-12-29 | 주식회사 하큐셀 | Cosmetic composition for decomposing fat |
CN114246238A (en) * | 2022-01-17 | 2022-03-29 | 闫洁 | Cistanche salsa and gardenia health tea |
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CN102308988A (en) * | 2011-07-08 | 2012-01-11 | 云南普洱思松科贸有限责任公司 | Dendrobium health product having function of human body immunization enhancement |
KR20200144249A (en) * | 2019-06-18 | 2020-12-29 | 주식회사 하큐셀 | Cosmetic composition for decomposing fat |
CN114246238A (en) * | 2022-01-17 | 2022-03-29 | 闫洁 | Cistanche salsa and gardenia health tea |
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