CN114983894A

CN114983894A - Acne-removing skin care product containing acne-removing composition and preparation method thereof

Info

Publication number: CN114983894A
Application number: CN202210730768.9A
Authority: CN
Inventors: 黄浩寒; 赖汉春
Original assignee: Guangzhou Tingcai Cosmetics Co ltd
Current assignee: Guangzhou Tingcai Cosmetics Co ltd
Priority date: 2022-06-24
Filing date: 2022-06-24
Publication date: 2022-09-02

Abstract

The invention discloses an acne-removing skin care product containing an acne-removing composition and a preparation method thereof, wherein the acne-removing composition comprises salicylic acid, paeonol, a radix sophorae flavescentis extract, proud, ecological nutrient solution, hydroxyethyl piperazine ethane sulfonic acid, beta-glucan and a centella asiatica extract, and the acne-removing composition can efficiently and mildly remove acnes, control oil and resist inflammation, can also enhance the skin repair function, recover pockmarks, remove pockmarks and brighten skin color. The acne-removing skin care product comprises an acne-removing composition, trehalose, xanthan gum, butanediol, 1, 2-hexanediol, p-hydroxyacetophenone, lemon (CITRUSLIMON) peel oil, PEG-40 hydrogenated castor oil and water.

Description

Acne-removing skin care product containing acne-removing composition and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to an acne-removing skin care product containing an acne-removing composition and a preparation method thereof.

Background

At present, with the rapid development of economic development in the world, over 85% of teenagers worldwide suffer from acne and related inflammations due to the reduction of air quality and the change of life and diet, and according to investigation, the acne has great influence on the psychology and social interaction of teenager patients, and most patients show anxiety, lack of confidence, fear of communication with people, self-inferiority and the like. Some teenagers also face the negative effects of the acne marks, and the acne marks have large influence on the facial beauty because the acne marks are pressed during the acne period, so that skin inflammation and damage of skin tissues are caused, even pyogenic infection can be caused.

In modern society, the skin can produce pox and pox due to pressure of life and work, excessive stimulation of food, unbalanced oil secretion, staying up all night and the like, a great part of adults are affected by the pox and pox, the acne can cause depression and anxiety, the acne lasts for a long time and is not easy to recover, the appearance and the mental health of people are affected, and therefore the work and the life are further negatively affected.

People have stronger requirements on cosmetics with the functions of effectively removing acnes, diminishing inflammation and promoting cell regeneration. In addition to the beauty of the face, the face acne seriously affects the beauty of the face and has negative influence on the life of people. Acne-removing skin care products are receiving more and more attention. Some acne-removing skin care products on the market currently have the following problems:

1. acne removal contains many western medicines such as antibiotics, hormone medicines, benzoyl peroxide, retinoic acid and the like, and a plurality of treatment methods are available, but the acne removal medicine has single efficacy and complicated operation, and brings great inconvenience to the use and treatment of patients. The acne removing western medicines are used at the initial stage, the acne removing speed is high, the acne is quickly relapsed, the medicine is used for a long time, certain medicine resistance can be generated, and finally the medicines hardly play a role; many acne-removing western medicines can cause side effects such as skin allergy and toxicity, and even cause dependence on human bodies. And the western medicines do not belong to raw materials allowed to be added in the cosmetics.

2. The traditional Chinese medicine has an acne removing effect, but the existing acne removing traditional Chinese medicine has the following problems:

1) the traditional Chinese medicine acne-removing medicine has good curative effect on a plurality of acnes, has certain pertinence, is ineffective for partial patients, or can be repeated after healing;

2) some traditional Chinese medicines have good acne removing effect, but can not remove acne scars, acne marks and acne pits;

3) some acne-removing traditional Chinese medicines can not remove nose blackheads and cause large pores.

3. The commonly used raw materials are various kinds of fruit acid raw materials, and have larger irritation to the skin, so that the skin sensitivity is increased, the skin tolerance is poor, and troubles are brought to the easily sensitive skin which is troubled by acne.

4. In order to achieve effective acne removing and anti-inflammatory effects, a high amount of anti-inflammatory bactericidal components are often required to be added, which often affects normal flora of skin, is not favorable for repairing and regenerating damaged cells, and has poor acne mark recovery effect, but the acne marks and acne scars generated after acne is eliminated cannot be well removed or relieved by the products, and most acne removing products have flat effects and are easy to leave the acne marks.

Disclosure of Invention

The invention provides an acne-removing skin care product containing an acne-removing composition and a preparation method thereof, aiming at helping skin eliminate inflammation caused by hypersecretion of sebum and propionibacterium acnes infection, recovering the health degree, elasticity and luster of the skin and solving the problem of acne growth on the skin.

The invention is implemented by the following technical scheme:

an acne-removing composition comprises the following components in parts by weight: 1-30 parts of package salicylic acid, 1-10 parts of paeonol, 1-20 parts of sophora flavescens root extract, 0.01-0.05 part of Piaoning, 1-15 parts of ecological nutrient solution, 1-15 parts of hydroxyethyl piperate sulfonic acid, 1-5 parts of beta-glucan, 1-5 parts of centella extract and 100 parts of water.

Preferably, the acne-removing composition comprises the following components in parts by weight: 25 parts of package salicylic acid, 5 parts of paeonol, 15 parts of sophora flavescens root extract, 0.02 part of proud, 10 parts of ecological nutrient solution, 10 parts of hydroxyethyl piperazine ethane sulfonic acid, 3 parts of beta-glucan, 4 parts of centella extract and 27.98 parts of water.

Preferably, the encapsulated salicylic acid is prepared by ultrasonic embedding, membrane filtration and spray drying of salicylic acid, dextrin and sesame amino acids;

the paeonol is a derivative of paeonol included by cyclodextrin;

the radix Sophorae Flavescentis extract is mixture of water, radix Sophorae Flavescentis extract, and phenoxyethanol;

the ecological nutrient solution is a mixture of inulin, water and alpha-glucan oligosaccharide.

The acne-removing skin care product comprises the following raw materials in percentage by weight: 1-20% of the acne-removing composition of any one of claims 1-3, 2-5% trehalose, 0.1-0.5% xanthan gum, 5-10% butanediol, 0.4-0.6% 1, 2-hexanediol, 0.4-0.6% p-hydroxyacetophenone, 0.01-0.05% lemon (CITRUS LIMON) peel oil, 0.05-0.25% PEG-40 hydrogenated castor oil, and 60-80% water.

Preferably, the acne-removing skin care product comprises the following raw materials in percentage by weight: 20% of acne-removing composition, 3% of trehalose, 0.25% of xanthan gum, 8% of butanediol, 0.5% of 1, 2-hexanediol, 0.5% of p-hydroxyacetophenone, 0.03% of lemon (CITRUS LIMON) peel oil, 0.15% of PEG-40 hydrogenated castor oil and 67.57% of water.

A preparation method of the acne-removing skin care product comprises the following steps:

adding deionized water into an emulsifying pot, dispersing xanthan gum in advance by using partial butanediol, adding into the emulsifying pot, stirring and homogenizing for 2-3min, adding trehalose, starting steam for heating, stirring and heating to 80-85 ℃, dissolving, and keeping the temperature for 20-30 min;

turning off steam heating, starting a cooling device, stirring, cooling to 60-65 ℃, adding a part of previously dissolved butanediol and p-hydroxyacetophenone, and uniformly stirring;

and (3) cooling to 40-45 ℃ under stirring, adding the 1, 2-hexanediol and the acne-removing composition, continuing stirring for 5-10min, adding the pre-solubilized lemon (CITRUS LIMON) peel oil and the PEG-40 hydrogenated castor oil, and uniformly stirring to obtain the acne-removing skin care product.

Preferably, the stirring speed in the step (1) is 30-40r/min, and the stirring homogenization conditions in the step (1) are as follows: the homogenizing speed is 1500-.

Preferably, the stirring speed in the step (2) and the step (3) is 20-30 r/min.

Preferably, the emulsifying pot includes the pot body, and the inside of the pot body is equipped with the stirring chamber, and the pot cover is installed to the upper end of the pot body, and the motor is installed at the top of pot cover, motor and drive shaft fixed connection, and the drive shaft runs through the pot cover and gets into in the stirring chamber, and drives a plurality of stirring pieces of fixedly connected with in the shaft, is equipped with the feed inlet on the pot cover, and the lower extreme of the pot body is equipped with the discharge gate.

Preferably, still include stabilizing mean, stabilizing mean and pot body fixed connection, stabilizing mean includes:

the upper end of the mounting plate is fixedly connected with the lower end of the pot body, the left end and the right end of the mounting plate are symmetrically provided with fixed blocks, the fixed blocks are fixedly connected with the side end of the pot body, one end of each fixed block, far away from the pot body, is fixedly connected with a first sliding block, one end of each sliding block, far away from the fixed blocks, is fixedly connected with a rack, and the rack is meshed with the gear;

the left end and the right end of the bottom plate are symmetrically provided with a first fixing plate, the first fixing plate is fixedly connected with a second fixing plate, the second fixing plate is fixedly connected with a third fixing plate, the left side and the right side of the upper end of the bottom plate are symmetrically provided with guide posts, the upper side and the lower side of each guide post are provided with a second sliding block in a sliding manner, a first spring is fixedly arranged between the second sliding blocks on the upper side and the lower side, the first spring is sleeved on the guide posts, the second sliding blocks are rotatably connected with the rotating rod, and the second sliding blocks on the upper side are fixedly connected with the first sliding blocks;

the movable end of the first telescopic rod is rotatably connected with the rotating rod on the left side, the fixed end of the first telescopic rod is rotatably connected with the rotating rod on the right side, and a spring II is fixedly sleeved on the movable end of the first telescopic rod;

the fixed end of the second telescopic rod is rotatably connected with the upper end of the bottom plate, the movable end of the second telescopic rod penetrates through the mounting plate and the lower end of the pot body to enter the lower side of the stirring cavity, the movable end of the second telescopic rod is fixedly connected with a stirring blade on the lower side of the stirring cavity, the fixed end of the second telescopic rod is fixedly connected with a first belt wheel and a second belt wheel, the first belt wheel is connected with a third belt wheel through a first conveying belt, and the second belt wheel is connected with a fourth belt wheel through a second conveying belt;

the two first rotating shafts are respectively and rotatably connected with the second fixing plates on the left side and the right side, the first rotating shaft on the right side is fixedly connected with the third belt wheel, and the first rotating shaft on the left side is fixedly connected with the fourth belt wheel;

the two rotating shafts II are respectively and rotatably connected with the fixing plates III on the left side and the right side, the rotating shafts II are fixedly connected with gears, a bevel gear I, a fixing sleeve and a rotating disc, the bevel gear I is meshed with the bevel gear II, and the bevel gear II is fixedly connected with the rotating shafts I;

the contact blocks are uniformly distributed on the fixing plate III in the circumferential direction, a spring III is arranged between the contact block and the fixing plate III, the contact blocks are in contact with the lugs, and the lugs are uniformly distributed on the fixing sleeve in the circumferential direction;

the first connecting shafts are eccentrically connected with the rotating discs on the left side and the right side respectively, the first connecting shafts are rotatably connected with the first connecting rods, the first connecting rods are rotatably connected with the second connecting rods through the second connecting shafts, the second connecting rods are in threaded connection with the pressing plate through bolts, and the pressing plate is in contact with the upper end of the pot body.

The acne-removing composition comprises the following components:

the encapsulated salicylic acid solves the problem that salicylic acid is difficult to dissolve, has a lasting release effect, is low in irritation, high in bioavailability and good in effect. The skin care product has the advantages of mildly peeling off cutin, inhibiting the activity of 5 alpha-reductase, inhibiting the proliferation of propionibacterium acnes, inhibiting the expression of proinflammatory factors, helping to recover skin barrier, inhibiting the generation of acnes, achieving the effects of controlling oil, removing acnes, resisting inflammation and repairing skin, dissolving constitutive substances among cutins, enabling the cutins to fall off, removing excessively thick cutins and promoting metabolism. The wrapped salicylic acid is fat-soluble, can permeate into the deep layer of the pore along the sebaceous gland secreting the grease, is beneficial to dissolving old accumulated cuticle in the pore, improves the situation of pore blockage, can block the formation of acne and reduce the expanded pore, acts on the cell of the hair follicle wall, can help to clear the blocked hair follicle, corrects abnormal cell shedding, can prevent the pore from being blocked, and has remarkable acne-removing effect.

Paeonol is a derivative of paeonol included with cyclodextrin, has improved effect, and has analgesic, antiinflammatory, repercussive, antioxidant, soothing, and pigmentation reducing effects.

The extract of the sophora flavescens ait root has good effects of fading red, resisting inflammation and relieving.

Piaoning has strong antibacterial activity, has strong killing capability on bacteria, staphylococcus, escherichia coli and the like, can quickly remove acnes, has good antibacterial effect on propionibacterium acnes, and is a killer for closed acnes. The action mechanism of the Piaoning is to start from bacterial cells, destroy the cell membranes of the bacterial cells, promote the degeneration of the bacterial cells, remove the skin sacs on the bacterial cells, accelerate the maturation speed of the pox, promote the secretion to flow out, and quickly eliminate the pox. The acne is inhibited from the perspective of Propionibacterium acnes, and the acne is also inhibited by breaking the anaerobic environment in practical application.

The ecological nutrient solution is a mixture of inulin, water and alpha-glucan oligosaccharide, natural carbohydrate components with plant sources and synergistic effect comprehensively optimizes a skin microorganism barrier and a prebiotic cosmetic, regulates the skin microorganism group, resists the proliferation of propionibacterium acnes through competitive inhibition, keeps the microorganism barrier of the skin ecological flora, avoids the invasion of harmful bacteria to the skin, protects the inner layer and the outer layer of the skin through a physical barrier of a horny layer, prevents the invasion of harmful molecules, restores the balance area of the skin in vivo through a biological barrier of an epidermis layer and a dermis layer, and ensures that the skin becomes comfortable and mild through rebuilding or strengthening weak or damaged tissues. Improving skin tolerance, causing no new drug resistance, and harming beneficial microorganism flora, and making beneficial bacteria stronger. Reduce irritation, erythema, and desquamation degree and roughness. Improving skin hydration.

The hydroxyethyl piperazine ethane sulfonic acid can soften cutin, but is very mild, promotes old cutin cells of skin epidermis to peel off, and can smooth and soften skin and brighten skin color. Promoting the absorption of active ingredients.

The beta-glucan has the effects of moisturizing, resisting inflammation, repairing and resisting aging, can increase the synthesis of collagen, and is beneficial to the repair and reconstruction of skin.

The centella asiatica extract plays a role in protection and recombination in the composition: promoting collagen synthesis, repairing skin, reducing wrinkle, scavenging free radicals, relieving inflammation, resisting photoaging, and removing acne marks and pockmarks.

The invention has the beneficial effects that:

(1) the centella extract can repair acne marks and acne marks, and the plant extracts paeonol and the sophora flavescens root extract in a specific ratio are used as synergistic active ingredients, so that the centella extract can play the functions of removing acne, inhibiting bacteria, relieving itching, fading red and repairing through the synergistic effect of the components.

(2) Although the proud tannin is used in a small amount, the proud tannin has a good bacteriostatic effect on propionibacterium acnes. The ecological nutrient solution added in the invention can improve the skin tolerance, can not cause new drug resistance, can not harm beneficial microbial communities and can make beneficial bacteria stronger. Reduce irritation, erythema, desquamation degree and roughness. Improving skin hydration.

(3) The invention does not contain various kinds of fruit acid raw materials, and the added coated salicylic acid has the advantages of lasting release effect, lower irritation, higher bioavailability and better effect. The wrapped salicylic acid is fat-soluble, can permeate into the deep layer of the pore along the sebaceous gland secreting the grease, is beneficial to dissolving old accumulated cuticle in the pore, improves the situation of pore blockage, can block the formation of acne and reduce the expanded pore, acts on the cell of the hair follicle wall, can help to clear the blocked hair follicle, corrects abnormal cell shedding, can prevent the pore from being blocked, and has remarkable acne-removing effect.

(4) The action purposes, the action routes and the mechanisms of all the components in the composition are different, and through proper component proportion, the effective components are mutually promoted in a synergistic manner, so that the synergistic effect is prominent, and the optimal synergistic effect is presented. The irritation of the anti-inflammatory and bactericidal component is reduced as much as possible, so that the effects of high efficiency, mild acne removing, oil control, anti-inflammation and relieving are achieved, and meanwhile, the skin repairing function, acne mark recovery, acne mark removal and skin color brightening are achieved. The long-term use is safe, mild and non-irritant; realizes mild acid stripping, bacteriostasis and anti-inflammation, obviously and locally repairs and improves the acne skin, and is more suitable for removing the acne of sensitive skin.

Drawings

The accompanying drawings, which are included to provide a further explanation of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description, serve to explain the invention and not to limit the invention. In the drawings:

FIG. 1 is a schematic view of the structure of an emulsifying pot according to the present invention;

FIG. 2 is a schematic view of the stabilizing mechanism of the present invention;

fig. 3 is a schematic view of the connection structure of the fixing cover in side view.

Wherein: 1. a motor; 11. a drive shaft; 12. a stirring sheet; 2. a pan body; 21. a stirring chamber; 3. a pot cover; 4. a feed inlet; 5. a discharge port; 6. a base plate; 61. a first fixing plate; 62. a second fixing plate; 63. a third fixing plate; 64. a second telescopic rod; 65. a first belt wheel; 66. a second belt wheel; 67. a first conveyor belt; 68. a second conveyor belt; 69. a belt wheel IV; 610. a third belt wheel; 611. rotating a first shaft; 612. a second bevel gear; 613. a first bevel gear; 614. a second rotating shaft; 615. a guide post; 616. a fixed block; 617. a first sliding block; 618. a second sliding block; 619. a first spring; 620. stirring blades; 621. mounting a plate; 622. rotating the disc; 623. a first connecting shaft; 624. a first connecting rod; 625. a second connecting shaft; 626. a second connecting rod; 627. pressing a plate; 628. a bolt; 629. fixing a sleeve; 630. a contact block; 631. a third spring; 632. a bump; 633. a rack; 634. rotating the rod; 635. a second spring; 636. a first telescopic rod; 637. a gear; 7. a cooling tank; 71. and a cooling cavity.

Detailed Description

The technical solution of the present invention is further described below with reference to specific examples, but the scope of the present invention is not limited to the following examples.

Example 1 acne removing composition of the invention

25 parts of package salicylic acid, 5 parts of paeonol, 15 parts of sophora flavescens root extract, 0.02 part of proud, 10 parts of ecological nutrient solution, 10 parts of hydroxyethyl piperazinethane sulfonic acid, 3 parts of beta-glucan, 4 parts of centella asiatica extract and 27.98 parts of water.

Example 2 acne removing composition of the invention

20 parts of package salicylic acid, 5 parts of paeonol, 20 parts of sophora flavescens root extract, 0.02 part of proud, 10 parts of ecological nutrient solution, 10 parts of hydroxyethyl piperate sulfonic acid, 2 parts of beta-glucan, 2 parts of centella extract and 30.98 parts of water.

Example 3 acne removing composition of the invention

15 parts of package salicylic acid, 3 parts of paeonol, 15 parts of sophora flavescens root extract, 0.01 part of proud, 15 parts of ecological nutrient solution, 15 parts of hydroxyethyl piperate sulfonic acid, 4 parts of beta-glucan, 4 parts of centella asiatica extract and 28.99 parts of water.

Comparative example 1

30 parts of package salicylic acid, 0.02 part of Piaoning, 15 parts of ecological nutrient solution, 15 parts of hydroxyethyl piperate sulfonic acid, 5 parts of beta-glucan, 5 parts of centella asiatica extract and 29.98 parts of water.

Comparative example 2

25 parts of package salicylic acid, 5 parts of paeonol, 15 parts of sophora flavescens root extract, 10 parts of ecological nutrient solution, 10 parts of hydroxyethyl piperazine sulfonic acid, 3 parts of beta-glucan, 4 parts of centella asiatica extract and 28 parts of water.

Comparative example 3

10 parts of paeonol, 20 parts of sophora flavescens root extract, 0.02 part of proud, 15 parts of ecological nutrient solution, 15 parts of hydroxyethyl piperate sulfonic acid, 5 parts of beta-glucan, 5 parts of centella asiatica extract and 29.98 parts of water.

Embodiment 4 the acne-removing skin care product of the invention and the preparation thereof

The formula is as follows: 20% of the acne-removing composition of example 1, 3% trehalose, 0.25% xanthan gum, 8% butylene glycol, 0.5% 1, 2-hexanediol, 0.5% p-hydroxyacetophenone, 0.03% lemon (CITRUS limo) peel oil, 0.15% PEG-40 hydrogenated castor oil, and 67.57% water.

The preparation method comprises the following steps: adding deionized water into an emulsifying pot, dispersing xanthan gum in advance by using partial butanediol, adding into the emulsifying pot, stirring and homogenizing for 2-3min, adding trehalose, starting steam for heating, stirring and heating to 80-85 ℃, dissolving, and keeping the temperature for 20-30 min;

closing steam heating, starting a cooling device, stirring, cooling to 60-65 ℃, adding a part of previously dissolved butanediol and p-hydroxyacetophenone, and uniformly stirring;

and (3) stirring and cooling to 40-45 ℃, adding the 1, 2-hexanediol and the acne-removing composition, continuously stirring for 5-10min, adding the pre-solubilized lemon (Citrus LIMON) peel oil and the PEG-40 hydrogenated castor oil, and uniformly stirring to obtain the acne-removing skin care product.

The stirring speed in the step (1) is 30-40r/min, and the stirring and homogenizing conditions in the step (1) are as follows: the homogenizing speed is 1500-2000 r/min.

The stirring speed in the step (2) and the step (3) is 20-30 r/min.

Example 5 acne-removing skin care product of the invention and preparation thereof

The formula is as follows: the acne-removing composition of example 1 was 15%, trehalose 5%, xanthan gum 0.3%, butylene glycol 8%, 1, 2-hexanediol 0.6%, p-hydroxyacetophenone 0.4%, lemon (CITRUS LIMON) peel oil 0.02%, PEG-40 hydrogenated castor oil 0.1%, and water 70.58%.

The preparation method is the same as example 4.

Example 6 acne-removing skin care product of the invention and preparation thereof

The formula is as follows: the acne-removing composition of example 1 is 10%, trehalose is 5%, xanthan gum is 0.4%, butylene glycol is 10%, 1, 2-hexanediol is 0.5%, p-hydroxyacetophenone is 0.5%, lemon (CITRUS LIMON) peel oil is 0.03%, PEG-40 hydrogenated castor oil is 0.15%, and water is 73.42%.

The preparation method is the same as example 4.

Example 7 acne-removing skin care product of the invention and preparation thereof

The formula is as follows: the acne-removing composition of example 2 was 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS LIMON) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

The preparation method is the same as example 4.

Example 8 acne-removing skin care product of the invention and preparation thereof

The formula is as follows: example 3 acne-removing composition 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS LIMON) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

The preparation method is the same as example 4.

Comparative example 4

The formula is as follows: comparative example 1 acne removal composition 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS LIMON) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

Comparative example 5

The formula is as follows: comparative example 2 acne removing composition 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS limo) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

Comparative example 6

The formula is as follows: comparative example 3 acne removal composition 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS LIMON) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

The preparation method is the same as example 4.

Experimental example a bacteriostatic experiment of acne removing composition acnes propionicum

The experimental method comprises the following steps: selecting a herpetic meat culture medium, and preparing a Propionibacterium acnes plate by a double-layer plate method, wherein the bacterial content of the plate is 10 ⁵ -10 ⁶ CFU/plate, 0.1g of the acne removing composition in the examples 1-3 and the comparative example 1 is taken and put on the plate, cultured for 24 hours under the anaerobic condition at 36 +/-1 ℃, and the bacteriostatic efficacy of the acne removing composition in the examples 1-3 and the comparative example 1 is compared by using a paper sheet diffusion method, namely a K-B method, through the area size of a bacteriostatic circle, and the specific experimental result is shown in Table 1.

TABLE 1 anti-acne composition bacteriostatic effect analysis

And (4) conclusion: the results in table 1 show that the acne removing compositions in examples 1 to 3 and comparative examples 1 to 3 have antibacterial effects, but the antibacterial effects of the examples 1 to 3 are obviously better than those of the comparative examples 1 and 2, and the antibacterial effect is not greatly influenced by the fact that no coated salicylic acid is added in the comparative example 3. In the acne-removing composition, a better antibacterial effect can be achieved through the synergistic effect of the asiatic pennywort herb extract, the paeonol and the sophora flavescens extract and the addition of a small amount of proud.

Test example two stability test of anti-acne skin care product

The experimental method comprises the following steps: the cold and heat resistance tests of examples 4-8 were performed by placing the test samples in a-10 ℃ cold box and a 40 ℃ oven, respectively, taking out the samples at 15, 30 and 60 days, respectively, and observing whether the test samples were not significantly different from those before the test after returning to room temperature, the specific results are shown in table 2.

TABLE 2 stability test results of acne-removing skin care products

And (4) conclusion: the results in table 2 show that the acne-removing skin care products prepared in examples 4 to 8 have no abnormal condition in the cold resistance and heat resistance experiments, which indicates that the acne-removing skin care products of the present invention have good stability and can be stored for a long time.

Test example three safety investigation of acne-removing skin care product

The experimental method comprises the following steps: the safety performance of the acne-removing skin care product is investigated by using a skin patch experiment. And selecting 50 volunteers as the skin patch experimental subjects, wherein the volunteers have no history of skin allergy and are 18-50 years old. Examining the acne-removing skin care products prepared in examples 4-8, volunteers were divided into 5 groups of 10 persons each. The selected area is not more than 50mm ² And qualified spot test equipment with the depth of about 1mm, adding about 0.02-0.025g of a test object into a small chamber of a spot test device, placing no substance in a control hole, sticking the spot test device added with the test object on the curved side of the forearm of a subject by using a hypoallergenic adhesive tape, and lightly pressing the test object by hands and palms to uniformly stick the test object on the skin for 24 hours. After 24h, the test article is removed, the skin reaction is observed according to the standard of table 3 after the indentation disappears, and the observation result is recorded.

TABLE 3 skin response grading Standard for skin Enclosed Patch test

The experimental results are as follows: through the skin patch experiment of the acne-removing skin care products prepared in examples 4-8, the skin reaction of the volunteers is observed after 24 hours, and no adverse skin reaction occurs in 50 volunteers, which indicates that the acne-removing skin care products prepared in examples 4-8 are safe to use.

Experimental example four acne-removing skin care product effect evaluation

The experimental method comprises the following steps: 120 volunteers were selected to participate in the evaluation of the effects of the acne-removing skin care products prepared in examples 4 to 8 and comparative example 2, and the 120 volunteers were 18 to 50 years old, had significant acne, acne or pox on the face, and had no history of skin allergy. 120 volunteers were divided into 6 groups of 20 persons each, and the volunteers wiped the acne-removing skin care products prepared in examples 4 to 8 and comparative example 23 times a day, scored for acne removal, oil control, acne scar removal, skin color brightening effects and application feeling of the acne-removing skin care products every week for 4 weeks, and counted to obtain an average value, and specific results are shown in table 4.

TABLE 4 evaluation results of the effectiveness of acne-removing skin care products

In the table, 9-10 points represent good, 7-8 points represent good, 5-6 points represent general, 3-4 points represent poor, and 1-2 points represent poor.

And (4) conclusion: the results in table 4 show that the acne removal skin care products prepared in examples 4-8 have obviously better effects of removing acne, controlling oil, removing acne marks and improving skin color than comparative examples 4-6, and the comparative example 6 does not contain wrapping salicylic acid, so that the acne removal effect is not obvious, and the smearing comfort level is greatly reduced. The acne-removing composition disclosed by the invention has the advantages that through proper component proportion, the effective components are mutually synergistically promoted, the synergistic effect is remarkable, and the optimal synergistic effect is presented. The acne-removing skin care product disclosed by the invention can reduce the irritation of the anti-inflammatory and bactericidal component as far as possible, so that the effects of high-efficiency and mild acne removing, oil control, inflammation resistance and soothing are achieved, and meanwhile, the skin repair function can be enhanced, acne marks can be recovered, acne marks can be removed, and the skin color can be brightened.

Example 9

On embodiment 4's basis, as shown in fig. 1, the emulsification pot includes the pot body 2, and the inside of the pot body 2 is equipped with stirring chamber 21, and pot cover 3 is installed to the upper end of the pot body 2, and motor 1 is installed at the top of pot cover 3, and motor 1 and drive shaft 11 fixed connection, drive shaft 11 run through in pot cover 3 gets into stirring chamber 21, and a plurality of stirring pieces 12 of fixedly connected with on the drive shaft 11 are equipped with feed inlet 4 on the pot cover 3, and the lower extreme of the pot body 2 is equipped with discharge gate 5.

The working principle and the beneficial effects of the technical scheme are as follows:

feed inlet 4 is arranged in adding the material to stirring chamber 21, and the emulsifying pot during operation, starter motor 1, motor 1 drive shaft 11 and rotate, and drive shaft 11 drives stirring piece 12 and rotates, stirs the material in driving chamber 21, and discharge gate 5 is used for discharging the material that stirs, and pot cover 3 and the installation of the pot body 2 can be dismantled pot cover 3 when 2 cleanness pot bodies, make things convenient for the clean step of the pot body 2.

Example 10

On the basis of embodiment 9, as shown in fig. 2-3, the pot further comprises a stabilizing mechanism, the stabilizing mechanism is fixedly connected with the pot body 2, and the stabilizing mechanism comprises:

the upper end of the mounting plate 621 is fixedly connected with the lower end of the pot body 2, the left end and the right end of the mounting plate 621 are symmetrically provided with fixed blocks 616, the fixed blocks 616 are fixedly connected with the side end of the pot body 2, one end of the fixed blocks 616, which is far away from the pot body 2, is fixedly connected with a first sliding block 617, one end of the first sliding block 617, which is far away from the fixed blocks 616, is fixedly connected with a rack 633, and the rack 633 is meshed with a gear 637;

the device comprises a base plate 6, wherein first fixing plates 61 are symmetrically arranged at the left end and the right end of the base plate 6, the first fixing plates 61 are fixedly connected with second fixing plates 62, the second fixing plates 62 are fixedly connected with third fixing plates 63, guide columns 615 are symmetrically arranged at the left side and the right side of the upper end of the base plate 6, second sliding blocks 618 are arranged at the upper side and the lower side of each guide column 615 in a sliding mode, a first spring 619 is fixedly arranged between the second sliding blocks 618 at the upper side and the lower side, the first spring 619 is sleeved on the guide columns 615, the second sliding blocks 618 are rotatably connected with a rotating rod 634, and the second sliding blocks 618 at the upper side are fixedly connected with a first sliding block 617;

the movable end of the first telescopic rod 636 is rotatably connected with the rotating rod 634 on the left side, the fixed end of the first telescopic rod 636 is rotatably connected with the rotating rod 634 on the right side, and a second spring 635 is fixedly sleeved on the movable end of the first telescopic rod 636;

the fixed end of the second telescopic rod 64 is rotatably connected with the upper end of the bottom plate 6, the movable end of the second telescopic rod 64 penetrates through the mounting plate 621 and the lower end of the pot body 2 to enter the lower side of the stirring cavity 21, the movable end of the second telescopic rod 64 is fixedly connected with the stirring blade 620 on the lower side of the stirring cavity 21, the fixed end of the second telescopic rod 64 is fixedly connected with a first belt wheel 65 and a second belt wheel 66, the first belt wheel 65 is connected with a third belt wheel 610 through a first conveying belt 67, and the second belt wheel 66 is connected with a fourth belt wheel 69 through a second conveying belt 68;

the two first rotating shafts 611 are respectively and rotatably connected with the second fixing plates 62 on the left side and the right side, the first rotating shaft 611 on the right side is fixedly connected with the third belt wheel 610, and the first rotating shaft 611 on the left side is fixedly connected with the fourth belt wheel 69;

the two second rotating shafts 614 are respectively and rotatably connected with the third fixing plates 63 on the left side and the right side, the second rotating shafts 614 are fixedly connected with a gear 637, a first bevel gear 613, a fixing sleeve 629 and a rotating disc 622, the first bevel gear 613 is meshed with a second bevel gear 612, and the second bevel gear 612 is fixedly connected with the first rotating shafts 611;

the contact blocks 630 are uniformly distributed on the third fixing plate 63 in the circumferential direction, a spring third 631 is arranged between the contact blocks 630 and the third fixing plate 63, the contact blocks 630 are in contact with the lugs 632, and the lugs 632 are uniformly distributed on the fixing sleeve 629 in the circumferential direction;

the two connecting shafts 623, the two connecting shafts 623 are respectively eccentrically connected with the rotating discs 622 on the left side and the right side, the connecting shafts 623 are rotatably connected with the connecting rods 624, the connecting rods 624 are rotatably connected with the connecting rods 626 through the connecting shafts 625, the connecting rods 626 are in threaded connection with the pressure plate 627 through bolts 628, and the pressure plate 627 is in contact with the upper end of the pot body 2.

through the installation of the stabilizing mechanism, when the emulsifying pot works, the emulsifying pot vibrates up and down, the mounting plate 621 is driven to move up and down, the mounting plate 621 drives the first sliding block 617 to slide up and down through the fixing block 616, the first sliding block 617 drives the second sliding block 618 on the upper side to slide up and down, the guide post 615 plays a role in guiding the up and down sliding of the first sliding block 617, the second sliding block 618 on the upper side slides up and down, the second sliding block 618 on the lower side is driven to slide up and down through the rotating rod 634, the second sliding blocks 618 on the upper side and the lower side move oppositely, the first spring 619 is compressed, the first telescopic rod 636 is driven to compress when the rotating rods 634 on the left side and the right side rotate, the second spring 635 is compressed, the up and down movement of the mounting plate 621 is buffered and damped under the combined action of the first spring 619 and the second spring 635, the up and down vibration phenomenon of the emulsifying pot is slowed down, and the working stability of the emulsifying pot is improved, and when the first sliding block 617 moves up and down, the rack 633 is driven to move up and down, the rack 633 is driven to drive the gear 636 to rotate, the gear 636 is driven to drive the second rotating shaft 614 to rotate, the second rotating shaft 614 is driven to drive the first bevel gear 613, the fixing sleeve 629 and the rotating disc 622 to rotate, the first bevel gear 613 is driven to drive the second bevel gear 612 to rotate, the second bevel gear 612 is driven to drive the fourth pulley 69 and the third pulley 610 to rotate through the first rotating shaft 611, the third pulley 610 is driven to drive the first pulley 65 to rotate through the first conveyor belt 67, the fourth pulley 69 is driven to rotate through the second conveyor belt 68, the first pulley 65 and the second pulley 66 are driven to rotate the second telescopic rod 64, the second telescopic rod 64 drives the stirring blade 620 to rotate, and can drive the second telescopic rod 64 to stretch and retract when the pot body 2 moves up and down, so that the stirring blade 620 always moves down and under the stirring cavity 21, the stirring blade 620 rotates, and material deposition under the stirring cavity 21 is avoided, further improve the stirring homogeneity of the material in stirring chamber 21, fixed cover 629 rotates, it rotates to drive lug 632, lug 632 promotes contact block 630 to rotate when rotating, contact block 630 rotates and makes spring three 631 compress, under the spring action of spring three 631, emulsion pot job stabilization nature has further been improved, rolling disc 622 rotates, it rotates to drive two 624 connecting rods to rotate through connecting axle 623, two 624 connecting rods drive two 626 connecting rods to reciprocate through two 625 connecting axles, two 626 connecting rods drive the clamp plate 627 to reciprocate, the clamp plate 627 reciprocates with the pot body 2 is synchronous, be used for keeping the stability of being connected of pot cover 3 and pot body 2, avoid pot cover 3 and pot body 2 to take place to become flexible.

Example 11

On the basis of embodiment 9, as shown in fig. 1, the cooling device includes a cooling tank 7, a cooling cavity 71 is provided inside the cooling tank 7, the cooling cavity 71 is used for placing an emulsifying pot, the pot body 2 is installed in the cooling cavity 71, a power pump is installed outside the cooling tank 7, the power pump is communicated with the liquid storage tank, a condensing device is provided in the liquid storage tank and used for cooling the cooling liquid in the liquid storage tank, and the power pump is used for circulating the cooling liquid in the cooling tank 7 and the liquid storage tank;

a first temperature sensor: the first temperature sensor is arranged in the stirring cavity 21 and used for detecting the temperature in the stirring cavity 21;

a second temperature sensor: the second temperature sensor is arranged in the cooling cavity 71 and is used for detecting the temperature of the cooling liquid in the cooling cavity 71;

an alarm device: the alarm is arranged outside the cooling box 7;

a controller: the controller is electrically connected with the temperature sensor I, the temperature sensor II and the alarm;

the controller controls the alarm to work based on the detection value of the first temperature sensor and the detection value of the second temperature sensor, and the method comprises the following steps:

step 1: the controller calculates the theoretical heat flux density of the cooling liquid in the cooling cavity 71 according to the temperature in the stirring cavity 21 detected by the first temperature sensor, the temperature in the cooling cavity 71 detected by the second temperature sensor and the formula (1);

where P is the theoretical heat flux density of the cooling fluid in the cooling cavity 71 and T ₁ Is the detected value of a temperature sensor one, T ₂ The detected value of the temperature sensor II is K, the heat conductivity coefficient of the side wall of the pot body 2 is S, the thickness of the side wall of the pot body 2 is S, and the thickness of the bottom of the pot body 2 is D;

step 2: the controller calculates the theoretical heat dissipation capacity of the pot body 2 when the cooling device works according to the theoretical heat flux density of the cooling liquid in the cooling cavity 71 calculated in the step 1 and a formula (2), compares the calculated theoretical heat dissipation capacity of the pot body 2 when the cooling device works with a preset heat dissipation capacity, and controls the alarm to give an alarm if the calculated theoretical heat dissipation capacity of the pot body 2 when the cooling device works is smaller than the preset heat dissipation capacity;

Q＝P*(C+B) (2)

q is the theoretical heat dissipation capacity of the pot body 2 when the cooling device works, C is the surface area of the side wall of the pot body 2, and B is the surface area of the bottom of the pot body 2;

wherein, T in the formula (1) ₁ Taking at 60 ℃, T ₂ Taking 10 deg.C, K73W/(m), S1 cm, D2 cm, and P to obtain 547.5 KJ/(m) ² *s)；

In the formula (2), C is 2m ² B is 0.5m ² And if the Q is calculated to be 4927.5MJ/h and is less than 5000MJ/h, the alarm gives an alarm.

the cooling device comprises a cooling box 7, a cooling cavity 71 is arranged in the cooling box 7, the pot body 2 is arranged in the cooling cavity 71, a power pump is arranged outside the cooling box 7 and communicated with the liquid storage box, a condensing device is arranged in the liquid storage box and used for cooling the cooling liquid in the liquid storage box, and the power pump is used for circulating the cooling box 7 and the cooling liquid in the liquid storage box; arranging a first temperature sensor in the stirring cavity 21 for detecting the temperature in the stirring cavity 21; a second temperature sensor is arranged in the cooling cavity 71 and used for detecting the temperature of the cooling liquid in the cooling cavity 71; the controller calculates the theoretical heat flux density of the cooling liquid in the cooling cavity 71 according to the temperature in the stirring cavity 21 detected by the first temperature sensor, the temperature in the cooling cavity 71 detected by the second temperature sensor and the formula (1); and then, calculating the theoretical heat dissipation capacity of the pot body 2 when the cooling device works according to the theoretical heat flux density of the cooling liquid in the cooling cavity 71 calculated in the step 1 and a formula (2), comparing the calculated theoretical heat dissipation capacity of the pot body 2 when the cooling device works with a preset heat dissipation capacity by using the controller, and if the calculated theoretical heat dissipation capacity of the pot body 2 when the cooling device works is smaller than the preset heat dissipation capacity, controlling an alarm to give an alarm by using the controller to remind a user to increase the circulating flow rate of the cooling liquid in the cooling tank 7 and the liquid storage tank or reduce the temperature of the cooling liquid in the liquid storage tank so as to improve the heat dissipation capacity of the pot body 2 and avoid the influence of too slow heat dissipation of the pot body 2 on the preparation efficiency of the acne-removing skin care product.

Finally, it should be noted that: the above-mentioned embodiments only represent some embodiments of the present invention, and are not intended to limit the present invention, and it should be understood that any modifications, equivalent substitutions, improvements, etc. made by those skilled in the art without departing from the spirit of the present invention should be included in the protection scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The acne removing composition is characterized by comprising the following components in parts by weight: 1-30 parts of package salicylic acid, 1-10 parts of paeonol, 1-20 parts of sophora flavescens root extract, 0.01-0.05 part of Piaoning, 1-15 parts of ecological nutrient solution, 1-15 parts of hydroxyethyl piperate sulfonic acid, 1-5 parts of beta-glucan, 1-5 parts of centella extract and 100 parts of water.

2. The acne treatment composition according to claim 1, wherein the acne treatment composition comprises the following components in parts by weight: 25 parts of package salicylic acid, 5 parts of paeonol, 15 parts of sophora flavescens root extract, 0.02 part of proud, 10 parts of ecological nutrient solution, 10 parts of hydroxyethyl piperazine ethane sulfonic acid, 3 parts of beta-glucan, 4 parts of centella extract and 27.98 parts of water.

3. The acne-removing composition according to claim 1, wherein the encapsulated salicylic acid is salicylic acid, dextrin or sesame amino acids, and is prepared by ultrasonic embedding, membrane filtration and spray drying;

the paeonol is a derivative of paeonol included by cyclodextrin;

4. The acne-removing skin care product is characterized by comprising the following raw materials in percentage by weight: 1-20% of the acne-removing composition of any one of claims 1-3, 2-5% trehalose, 0.1-0.5% xanthan gum, 5-10% butanediol, 0.4-0.6% 1, 2-hexanediol, 0.4-0.6% p-hydroxyacetophenone, 0.01-0.05% lemon (CITRUS LIMON) peel oil, 0.05-0.25% PEG-40 hydrogenated castor oil, and 60-80% water.

5. The acne-removing skin care product according to claim 4, which is characterized by comprising the following raw materials in percentage by weight: the acne treatment composition of any one of claims 1-3 20%, trehalose 3%, xanthan gum 0.25%, butylene glycol 8%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5%, lemon (CITRUS LIMON) peel oil 0.03%, PEG-40 hydrogenated castor oil 0.15%, and water 67.57%.

6. A preparation method of the acne-removing skin care product for preparing the acne-removing skin care product according to any one of claims 4 to 5, which is characterized by comprising the following steps:

7. The preparation method of the acne-removing skin care product according to claim 6, wherein the stirring speed in step (1) is 30-40r/min, and the stirring homogenization conditions in step (1) are as follows: the homogenizing speed is 1500-.

8. The preparation method of the acne-removing skin care product according to claim 6, wherein the stirring speed in the step (2) and the step (3) is 20-30 r/min.

9. The preparation method of the acne-removing skin care product according to claim 6, wherein the emulsifying pot comprises a pot body (2), a stirring cavity (21) is arranged inside the pot body (2), a pot cover (3) is installed at the upper end of the pot body (2), a motor (1) is installed at the top of the pot cover (3), the motor (1) is fixedly connected with a driving shaft (11), the driving shaft (11) penetrates through the pot cover (3) and enters the stirring cavity (21), a plurality of stirring sheets (12) are fixedly connected to the driving shaft (11), a feeding hole (4) is formed in the pot cover (3), and a discharging hole (5) is formed in the lower end of the pot body (2).

10. The preparation method of the acne-removing skin care product according to claim 6, characterized by further comprising a stabilizing mechanism, wherein the stabilizing mechanism is fixedly connected with the pot body (2), and the stabilizing mechanism comprises:

the pot body is characterized by comprising a mounting plate (621), the upper end of the mounting plate (621) is fixedly connected with the lower end of the pot body (2), fixing blocks (616) are symmetrically arranged at the left end and the right end of the mounting plate (621), the fixing blocks (616) are fixedly connected with the side end of the pot body (2), one end, far away from the pot body (2), of each fixing block (616) is fixedly connected with a first sliding block (617), one end, far away from the fixing blocks (616), of each sliding block (617) is fixedly connected with a rack (633), and the rack (633) is meshed with a gear (637);

the guide post structure comprises a base plate (6), wherein first fixing plates (61) are symmetrically arranged at the left end and the right end of the base plate (6), the first fixing plates (61) are fixedly connected with second fixing plates (62), the second fixing plates (62) are fixedly connected with third fixing plates (63), guide posts (615) are symmetrically arranged at the left side and the right side of the upper end of the base plate (6), second sliding blocks (618) are arranged at the upper side and the lower side of each guide post (615) in a sliding mode, a first spring (619) is fixedly arranged between the second sliding blocks (618) at the upper side and the lower side, the first spring (619) is sleeved on the guide posts (615), the second sliding blocks (618) are rotatably connected with rotating rods (634), and the second sliding blocks (618) at the upper side are fixedly connected with the first sliding blocks (617);

the telescopic rod I (636), the movable end of the telescopic rod I (636) is rotatably connected with the rotating rod (634) on the left side, the fixed end of the telescopic rod I (636) is rotatably connected with the rotating rod (634) on the right side, and a spring II (635) is fixedly sleeved on the movable end of the telescopic rod I (636);

the fixed end of the second telescopic rod (64) is rotatably connected with the upper end of the bottom plate (6), the movable end of the second telescopic rod (64) penetrates through the mounting plate (621) and the lower end of the pot body (2) to enter the lower side of the stirring cavity (21), the movable end of the second telescopic rod (64) is fixedly connected with the stirring blade (620) on the lower side of the stirring cavity (21), the fixed end of the second telescopic rod (64) is fixedly connected with the first belt wheel (65) and the second belt wheel (66), the first belt wheel (65) is connected with the third belt wheel (610) through the first conveying belt (67), and the second belt wheel (66) is connected with the fourth belt wheel (69) through the second conveying belt (68);

the two first rotating shafts (611), the two first rotating shafts (611) are respectively and rotatably connected with the second fixing plates (62) on the left side and the right side, the first rotating shaft (611) on the right side is fixedly connected with the third belt wheel (610), and the first rotating shaft (611) on the left side is fixedly connected with the fourth belt wheel (69);

the two second rotating shafts (614), the two second rotating shafts (614) are respectively and rotatably connected with the third fixing plates (63) on the left side and the right side, the second rotating shafts (614) are fixedly connected with the gear (637), the first bevel gear (613), the fixing sleeve (629) and the rotating disc (622), the first bevel gear (613) is meshed with the second bevel gear (612), and the second bevel gear (612) is fixedly connected with the first rotating shaft (611);

the contact blocks (630) are circumferentially and uniformly distributed on the third fixing plate (63), a third spring (631) is arranged between the contact blocks (630) and the third fixing plate (63), the contact blocks (630) are in contact with the lugs (632), and the lugs (632) are circumferentially and uniformly distributed on the fixing sleeve (629);

the two connecting shafts (623), the two connecting shafts I (623) are respectively eccentrically connected with the rotating discs (622) on the left side and the right side, the connecting shafts I (623) are rotatably connected with the connecting rods I (624), the connecting rods I (624) are rotatably connected with the connecting rods II (626) through the connecting shafts II (625), the connecting rods II (626) are in threaded connection with the pressing plate (627) through bolts (628), and the pressing plate (627) is in contact with the upper end of the pot body (2).