CN114981310A - 一种全过程靶向分子及其药物复合物在构建递药系统中的应用 - Google Patents

一种全过程靶向分子及其药物复合物在构建递药系统中的应用 Download PDF

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CN114981310A
CN114981310A CN202180008713.0A CN202180008713A CN114981310A CN 114981310 A CN114981310 A CN 114981310A CN 202180008713 A CN202180008713 A CN 202180008713A CN 114981310 A CN114981310 A CN 114981310A
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drug
molecule
tumor
drugs
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陆伟跃
周建芬
柴芝兰
吴荪奕
谢操
王浩
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Fudan University
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Abstract

本发明属于药学领域，披露了一种具有靶向脑毛细血管内皮细胞(跨血‑脑屏障)、肿瘤新生血管内皮细胞(跨血‑肿瘤屏障)、肿瘤拟态血管、肿瘤细胞和肿瘤干细胞的全过程靶向分子，以及其修饰的药物复合物、纳米载药系统在肿瘤诊断和靶向治疗中的用途。本发明的全过程靶向分子、其药物复合物及其构建的纳米载药系统，可将所携带的影像分子、治疗药物、纳米载药系统靶向递送至脑内肿瘤组织，或靶向递送至具备脑转移特征的外周肿瘤组织。

Description

PCT国内申请，说明书已公开。

Claims (16)

  1. PCT国内申请，权利要求书已公开。
CN202180008713.0A 2020-01-23 2021-01-20 一种全过程靶向分子及其药物复合物在构建递药系统中的应用 Pending CN114981310A (zh)

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CN115825442A (zh) * 2021-11-23 2023-03-21 中国人民解放军总医院第一医学中心 钙钛矿纳米晶在制备用于肿瘤诊断或治疗的探针中的应用
CN114522245B (zh) * 2022-03-04 2024-06-18 宿州学院 一种靶向端粒酶纳米药物递送系统及其制备方法与应用
CN114806546A (zh) * 2022-05-18 2022-07-29 南京大学 基于荧光分子的有机框架材料及其制备方法和应用
CN115006368B (zh) * 2022-07-01 2023-03-14 重庆大学 细胞膜包被纳米药物及其应用
CN115919766B (zh) * 2022-12-27 2023-10-24 国科宁波生命与健康产业研究院 一种复合纳米胶束及其制备方法和应用

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