CN114955241A - Gene diagnosis kit for systemic lupus erythematosus and use method thereof - Google Patents
Gene diagnosis kit for systemic lupus erythematosus and use method thereof Download PDFInfo
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- CN114955241A CN114955241A CN202210597789.8A CN202210597789A CN114955241A CN 114955241 A CN114955241 A CN 114955241A CN 202210597789 A CN202210597789 A CN 202210597789A CN 114955241 A CN114955241 A CN 114955241A
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- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 77
- 201000000596 systemic lupus erythematosus Diseases 0.000 title claims abstract description 49
- 238000003745 diagnosis Methods 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title claims abstract description 20
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 148
- 239000002184 metal Substances 0.000 claims description 74
- 229920000742 Cotton Polymers 0.000 claims description 19
- 238000009007 Diagnostic Kit Methods 0.000 claims description 16
- 238000007789 sealing Methods 0.000 claims description 10
- 238000003825 pressing Methods 0.000 claims description 9
- 238000007598 dipping method Methods 0.000 claims description 6
- 230000000903 blocking effect Effects 0.000 claims description 3
- 230000006835 compression Effects 0.000 claims description 2
- 238000007906 compression Methods 0.000 claims description 2
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000001514 detection method Methods 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
- B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
- B65D77/0446—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid or semi-rigid and the outer container being of polygonal cross-section not formed by folding or erecting one or more blanks
- B65D77/0453—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid or semi-rigid and the outer container being of polygonal cross-section not formed by folding or erecting one or more blanks the inner container having a polygonal cross-section
- B65D77/046—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid or semi-rigid and the outer container being of polygonal cross-section not formed by folding or erecting one or more blanks the inner container having a polygonal cross-section and being a tray or like shallow container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/02—Internal fittings
- B65D25/10—Devices to locate articles in containers
- B65D25/101—Springs, elastic lips, or other resilient elements to locate the articles by pressure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/36—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents adapted to be used for non-packaging purposes after removal of contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2577/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks, bags
- B65D2577/04—Articles or materials enclosed in two or more containers disposed one within another
- B65D2577/041—Details of two or more containers disposed one within another
- B65D2577/042—Comprising several inner containers
- B65D2577/045—Comprising several inner containers stacked
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a gene diagnosis kit for systemic lupus erythematosus and a using method thereof, and provides a scheme which comprises a kit and a plurality of reagent tubes positioned in the kit, wherein the kit is connected with a sliding plate in a sliding way, the inner wall of the bottom of the kit is fixedly connected with a plurality of first springs, the top ends of the first springs are fixedly connected with the bottom of the sliding plate, and the top of the sliding plate is rotatably connected with a rotating shaft. The patient can be made to perform multiple sets of diagnoses for obtaining accurate data.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a gene diagnosis kit for systemic lupus erythematosus and a using method thereof.
Background
Systemic lupus erythematosus is an autoimmune disease, the course of disease is slow, and the disease is difficult to be found by people at the early stage of disease, the systemic lupus erythematosus can cause the pathological changes of multiple tissues and multiple organs of a body, and causes serious damage to the body, and the cause of the systemic lupus erythematosus is unknown, so that the treatment is difficult, the systemic lupus erythematosus cannot be cured radically by the existing medicine, and only can relieve the disease to a certain extent.
In the detection of systemic lupus erythematosus, the diagnosis of gene collection requiring systemic lupus erythematosus, however, in the prior art, when the reagent kit is carried, the reagent tube in the reagent kit often shakes, so that the reagent tube collides with the inner wall of the reagent kit, and therefore the detection reagent in the reagent tube may be poured out, but also needs the patient to search for a cotton swab to collect when collecting the systemic lupus erythematosus gene, in addition, after the collection is finished, the gene collected by the cotton swab is inserted into the reagent tube, so that the reagent in the reagent tube is mixed with the gene, in order to rapidly mix the reagent and the gene, the patient is often required to forcibly shake the reagent tube to uniformly mix the reagent and the gene, in addition, only one reagent tube is used in the existing kit, and multiple gene acquisition can not be carried out to compare multiple groups of data.
Disclosure of Invention
The invention aims to solve the problems that in the prior art, a reagent tube in a reagent box often shakes, a patient needs to forcibly shake the reagent tube, and genes cannot be collected for multiple times for comparison of multiple groups of data, and provides a gene diagnosis kit for systemic lupus erythematosus and a using method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the gene diagnosis kit for the systemic lupus erythematosus comprises a kit body and a plurality of reagent tubes positioned in the kit body, wherein a sliding plate is connected in the kit body in a sliding mode, a plurality of first springs are fixedly connected to the inner wall of the bottom of the kit body, the top ends of the first springs are fixedly connected with the bottom of the sliding plate, a rotating shaft is rotatably connected to the top of the sliding plate, a clamping plate is fixedly connected to the top end of the rotating shaft, the sliding box is connected to the inner wall of the bottom of the kit body in a sliding mode, arc-shaped wedge plates are fixedly connected to the inner walls of the sides, far away from each other, of the kit body, and a broken groove is formed in the arc-shaped wedge plate positioned on the right side;
a sealing component capable of sealing the kit is arranged in the kit;
a fixing component for fixing the reagent tube is arranged in the clamping plate;
the top of the sliding plate is provided with a rotating assembly for driving the clamping disc to rotate;
the inner wall of the bottom of the kit is provided with a control component for controlling the sliding of the sliding box.
Preferably, the closed component comprises two symmetrical support plates fixedly connected to the top of the kit, one side of the two support plates, which are close to each other, is rotatably connected with a rotating rod, the outer wall of the rotating rod is fixedly sleeved with a cover plate, the outer wall of the rotating rod is sleeved with two torsional springs, one ends, which are close to each other, of the two torsional springs are fixedly connected with the cover plate, the other ends, which are far away from each other, of the two torsional springs are respectively and fixedly connected with the support plates, the top of the kit is provided with a first groove, the bottom of the cover plate is fixedly connected with a fixing lug which extends into the first groove, one side of the kit is provided with a second groove, a pin penetrates through the inner wall of one side, which is close to the support plates, in a sliding manner, one end, which is close to the support plates, the other end of the pin is fixedly connected with a fixing plate which is located in the second groove, and the outer wall of the pin is sleeved with a tension spring fixedly connected with the fixing plate, the other end of the tension spring is fixedly connected with the inner wall of one side of the second groove close to the support plate.
Preferably, the fixing component comprises a plurality of placing grooves arranged in the clamping plate, the reagent tubes are positioned in the placing grooves, a cavity is arranged in the clamping plate, the bottom inner wall of the cavity is rotatably connected with a rotating shaft, the outer wall of the rotating shaft is fixedly sleeved with a turntable, a plurality of arc-shaped sliding grooves are arranged in the turntable, the outer wall of the clamping plate is provided with a plurality of rectangular grooves, the inner wall of one side, close to each other, of the rectangular grooves is provided with a sliding rod in a sliding way, one end, close to each other, of the sliding rods extends into the cavity, the top of each sliding rod is fixedly connected with a convex block matched with the arc-shaped sliding grooves, the outer wall of each sliding rod is sleeved with a second spring positioned in the rectangular groove, one end, far away from the cavity, of each sliding rod is fixedly connected with a clamping plate contacted with the reagent tubes, and the two ends of the second spring are fixedly connected with the clamping plate and the inner wall of one side of the rectangular groove respectively, one side fixedly connected with and arc wedge matched with wedge of cavity are kept away from to splint, the top fixedly connected with of slide two with kit sliding connection's dead lever, and the top of dead lever touches with the bottom of apron.
Preferably, the runner assembly includes stopper and the fixed horizontal pole of fixed connection at the slide top, the fixed cover of outer wall of pivot is equipped with the gear, the top of slide is equipped with the metal rack with gear engaged with, one side fixedly connected with slider that fixed horizontal pole is close to the metal rack, one side that the gear was kept away from to the metal rack is equipped with the rectangle spout with slider sliding fit.
Preferably, the control assembly comprises a transverse plate fixedly connected to the inner wall of the bottom of the kit, the transverse plate is elastically connected with the sliding box through a plurality of third springs, a plurality of cotton collecting sticks are arranged in the sliding box, one side of the sliding box, which is close to the transverse plate, is fixedly connected with a connecting block, the bottom of the sliding plate is provided with a sliding groove, a trapezoidal block extending into the connecting block is slidably connected in the sliding groove, a fourth spring is fixedly connected to the top end of the trapezoidal block, and the top end of the fourth spring is fixedly connected with the inner wall of the top of the sliding groove.
Preferably, one side that the backup pad was kept away from to the kit is equipped with the through-hole, and the metal rack is corresponding with the through-hole, be equipped with the magnet that touches mutually with the metal rack in the through-hole, the other end fixedly connected with of magnet supports the feeler lever, the one end fixedly connected with fixed block that the metal rack was kept away from to the feeler lever, and the bottom of fixed block and the top fixed connection of sliding box.
Preferably, one side fixedly connected with arc briquetting that splint are close to the axis of rotation, and the bottom of arc briquetting and reagent pipe touch mutually, can fix the reagent pipe from the top through the arc briquetting.
Preferably, two arc-shaped grooves matched with the arc-shaped wedge plates are formed in the sliding plate, and the arc-shaped wedge plates can just penetrate through the arc-shaped grooves when the sliding plate moves up and down.
Preferably, a plurality of sliding rods are fixedly connected to the inner wall of the bottom of the reagent box, the top ends of the sliding rods penetrate through the sliding plate in a sliding mode, and the sliding plate can be guided when the sliding plate slides through the sliding rods.
The using method of the gene diagnosis kit for systemic lupus erythematosus comprises the following steps:
s1, pulling the fixing plate and the pin outwards, separating the pin from the fixing lug, stretching the tension spring, and opening the reagent box because the first spring and the second spring are both in a compressed state because the torsion spring is in a power storage state before, and after the pin releases the brake on the fixing lug, the cover plate starts to rotate anticlockwise;
s2, when the cover plate rotates anticlockwise, the sliding plate slides upwards under the action of the elastic force of the first spring, the sliding plate drives the clamping disc to slide upwards, when the sliding plate slides, the arc wedge plate can penetrate through the sliding plate, the clamping disc is separated from the two arc wedge plates, after the wedge block loses the blocking of the arc wedge plate, the wedge block, the clamping plates and the sliding rod slide outwards under the action of the elastic force of the second spring, and under the matching of the arc sliding groove and the convex block, the rotating disc starts to rotate clockwise, so that the clamping of a plurality of reagent tubes is simultaneously released by the plurality of clamping plates, and the clamping disc is separated from the reagent box at this time;
s3, when the sliding plate moves upwards, firstly, the sliding box is abutted by hands, so that the sliding box is fixed temporarily, after the sliding plate moves for a certain distance, the metal rack and the magnet are staggered, the abutment on the sliding box is released, and the trapezoidal block is separated from the connecting block;
s4, taking out the collecting cotton swab from the sliding box, dipping the genes from the systemic lupus erythematosus through the collecting cotton swab, inserting the genes dipped by the collecting cotton swab into a reagent tube, mixing the reagent in the reagent tube with the systemic lupus erythematosus genes, dipping a plurality of groups of genes, and respectively inserting the genes into the reagent tube;
s5, reinserting the reagent tube mixed with the gene and the reagent into the placing groove, reversely rotating the cover plate, and reclosing the reagent box, wherein when the cover plate rotates clockwise, the cover plate pushes the fixing rod to enable the sliding plate and the clamping disc to move downwards again, the first spring starts to compress, in the downward movement process of the clamping disc, the clamping plates and the sliding rods can move towards the middle through the matching of the arc-shaped wedge plate and the wedge block, the second spring starts to compress, then the rotary disc rotates anticlockwise under the action of the arc-shaped sliding groove and the convex block, and meanwhile, the clamping plates respectively clamp and fix the reagent tube;
s6, the sliding box and the fixing block are pushed to slide towards the inner wall of the reagent box, the touch rod and the magnet extend into the reagent box, the magnet can be close to the metal rack, the bottom end of the trapezoidal block is in contact with the top of one side of the connecting block at the moment, the trapezoidal block cannot extend into the connecting block, the magnetic attraction of the magnet on the metal rack is large enough, the metal rack can be sucked out of the reagent box, the metal rack is pulled outwards quickly through manpower, and due to the fact that the gear is meshed with the metal rack, in the process that the metal rack slides outwards, the metal rack drives the rotating shaft and the clamping disc to rotate quickly through the gear, the reagent tube can be driven to rotate, and reagents and genes in the reagent tube are fully mixed;
s7, after reagent and gene intensive mixing in the reagent tube were accomplished, with sliding box and fixed block to the inside promotion of kit, the connecting block extends to in the reagent box under the drive of sliding box, the trapezoidal piece card system to sliding box in extending to the connecting block again under the cooperation of trapezoidal piece and fourth spring, and magnet can promote metal rack and remove to the stopper direction, and then the cooperation of magnet and stopper can be fixed with metal rack, avoid the kit to appear rocking when the clamping dish appear rotating.
Compared with the prior art, the invention provides a gene diagnosis kit for systemic lupus erythematosus, which has the following beneficial effects:
1. this a slip box for systemic lupus erythematosus's gene diagnosis kit's one side fixedly connected with connecting block that is close to the diaphragm, sliding connection has the trapezoidal piece that extends to in the connecting block in the sliding tray, and in slide up-moving, the trapezoidal piece breaks away from the connecting block, and the slip box can pop out from the kit under the spring action of third spring, and then can pop out the slip box from the kit when opening the kit and make the arc wall shift up, makes things convenient for the patient to take out the collection cotton stick and carries out gene collection.
2. This a stopper and fixed horizontal pole at slide top for gene diagnosis kit for systemic lupus erythematosus, the top of slide is equipped with the metal rack with gear engaged with, one side fixedly connected with slider that fixed horizontal pole is close to metal rack, one side that metal rack kept away from the gear is equipped with the rectangle spout with slider sliding fit, when through magnet with metal rack from kit suction, can be through the manual work with metal rack outside quick pulling, and then drive the quick rotation of clamping dish, and then can make reagent and gene in the reagent pipe mix, need not to rock the reagent pipe through manual round trip.
3. This a gene diagnosis kit for systemic lupus erythematosus's one side fixedly connected with of fixed block extends to the conflict pole in the through-hole, the magnet that other end fixedly connected with and the metal rack of feeler lever touched mutually, when feeler lever and magnet moved to the outside, can take out metal rack from the kit through the magnetic attraction of magnet to metal rack, make things convenient for the later stage to rotate clamping dish, and when will be to feeler lever and magnet insert in the through-hole, can fix metal rack through the cooperation of magnet and stopper, avoid clamping dish to appear rocking.
4. This a gene diagnosis kit for systemic lupus erythematosus's equal fixedly connected with arc wedge of one side inner wall that the kit kept away from each other, it is a plurality of the equal fixedly connected with of one side and arc wedge matched with wedge of splint keeping away from each other, at the in-process that the slide drove the clamping dish rebound, the braking to the wedge is gradually relieved to the arc wedge, wedge and splint move to the outside under the spring action of second spring, and then relieve the fixed to the reagent pipe, conveniently take out the reagent pipe from the clamping dish, otherwise, equally can be fixed with the reagent pipe through splint rotating the in-process that the apron seals the kit.
The sliding plate type gene analyzer is simple in structure, the reagent box is opened by rotating the cover plate, so that the sliding plate can move upwards, the fixing of the clamping plate on the reagent tube is released, the sliding box can be popped out of the reagent box, a user can conveniently and quickly collect genes and mix the genes with the reagents in the reagent tube, in addition, the clamping plate can be quickly driven to rotate by pulling the metal rack outwards, the reagents in the reagent tube and the genes are fully mixed, and a plurality of reagent tubes are arranged in the clamping plate, so that a patient can carry out multi-group diagnosis and accurate data can be obtained.
Drawings
FIG. 1 is a three-dimensional view of the whole of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 2 is a sectional front view showing the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 3 is an enlarged view of the site A of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 4 is an enlarged view of the site B of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 5 is a three-dimensional view of the kit and the arc wedge plate of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 6 is a three-dimensional sectional view of a slide cassette of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 7 is a three-dimensional view of a clamping member of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 8 is a three-dimensional sectional view of the holding plate of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 9 is a three-dimensional sectional view of the holder assembly of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 10 is a three-dimensional sectional view of a rotary member of the gene diagnostic kit for systemic lupus erythematosus according to the present invention;
FIG. 11 is a three-dimensional view of the interior of the kit of the gene diagnostic kit for systemic lupus erythematosus according to the second embodiment of the present invention.
In the figure: 1. a kit; 2. a support plate; 3. rotating the rod; 4. a cover plate; 5. a torsion spring; 6. fixing the ear; 7. a first groove; 8. a second groove; 9. a pin; 10. a fixing plate; 11. a tension spring; 12. a first spring; 13. an arc-shaped slot; 14. a slide plate; 15. a rotating shaft; 16. a clamping disc is arranged; 17. a placement groove; 18. a reagent tube; 19. a cavity; 20. a rotating shaft; 21. a turntable; 22. an arc-shaped chute; 23. a slide bar; 24. a bump; 25. a rectangular groove; 26. a second spring; 27. a splint; 28. a wedge block; 29. an arc wedge plate; 30. breaking the groove; 31. a fixing rod; 32. a slide cassette; 33. collecting cotton swabs; 34. a transverse plate; 35. a third spring; 36. a gear; 37. a limiting block; 38. a metal rack; 39. fixing the cross bar; 40. a rectangular chute; 41. a slider; 42. a sliding groove; 43. a trapezoidal block; 44. a fourth spring; 45. connecting blocks; 46. a fixed block; 47. a touch bar; 48. a magnet; 49. an arc-shaped pressing block; 50. a slide bar; 51. and a through hole.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example 1:
referring to fig. 1-10, a gene diagnostic kit for systemic lupus erythematosus includes a kit 1 and a plurality of reagent tubes 18 located in the kit 1, a slide plate 14 is slidably connected in the kit 1, a plurality of first springs 12 are fixedly connected to the bottom inner wall of the kit 1, the top ends of the first springs 12 are fixedly connected to the bottom of the slide plate 14, a rotating shaft 15 is rotatably connected to the top of the slide plate 14, a clamping plate 16 is fixedly connected to the top end of the rotating shaft 15 through a bolt, a sliding box 32 is slidably connected to the bottom inner wall of the kit 1, arc wedge plates 29 are fixedly connected to the inner walls of the sides of the kit 1 away from each other through bolts, a break groove 30 is provided in the arc wedge plate 29 on the right side, a fixing component for fixing the reagent tubes 18 is provided in the clamping plate 16 which is a sealing component capable of sealing the kit 1 is provided in the kit 1, a rotating component for driving the clamping plate 16 to rotate is provided at the top of the slide plate 14, the inner wall of the bottom of the kit 1 is provided with a control component for controlling the sliding of the sliding box 32, one side of the kit 1, which is far away from the support plate 2, is provided with a through hole 51, the metal rack 38 corresponds to the through hole 51, a magnet 48 which is in contact with the metal rack 38 is arranged in the through hole 51, the other end of the magnet 48 is fixedly connected with a touch rod 47 through a bolt, one end of the touch rod 47, which is far away from the metal rack 38, is fixedly connected with a fixed block 46 through a bolt, the bottom end of the fixed block 46 is fixedly connected with the top of the sliding box 32 through a bolt, the metal rack 38 can be taken out of the kit 1 through the magnetic attraction of the magnet 48 to the metal rack 38, the clamping plate 16 is convenient to rotate in the later period, when the touch rod 47 and the magnet 48 are inserted into the through hole 51, the metal rack 38 can be fixed through the matching of the magnet 48 and the limiting block 37, the shaking of the clamping plate 16 is avoided, two arc-shaped grooves 13 which are matched with the arc-shaped wedge plate 29 are arranged in the sliding plate 14, the arc wedge plate 29 just can pass through the arc slot 13 when the sliding plate 14 moves up and down.
In the invention, the closed component comprises two symmetrical support plates 2 fixedly connected to the top of a reagent kit 1 through bolts, one sides of the two support plates 2 close to each other are rotatably connected with a rotating rod 3, the outer wall of the rotating rod 3 is fixedly sleeved with a cover plate 4, the outer wall of the rotating rod 3 is sleeved with two torsion springs 5, the ends of the two torsion springs 5 close to each other are fixedly connected with the cover plate 4, the ends of the two torsion springs 5 far away from each other are respectively fixedly connected with the support plates 2, the top of the reagent kit 1 is provided with a first groove 7, the bottom of the cover plate 4 is fixedly connected with a fixing lug 6 extending into the first groove 7 through the bolts, one side of the reagent kit 1 is provided with a second groove 8, the inner wall of one side of the second groove 8 close to the support plate 2 is provided with a pin 9 in a sliding way, one end of the pin 9 close to the support plate 2 extends into the fixing lug 6, and the other end of the pin 9 is fixedly connected with a fixing plate 10 positioned in the second groove 8 through the bolts, the outer wall cover of round pin 9 is equipped with the extension spring 11 with fixed plate 10 fixed connection, and the other end of extension spring 11 and the one side inner wall fixed connection that second recess 8 is close to backup pad 2.
In the invention, the fixing component comprises a plurality of placing grooves 17 arranged in a clamping disc 16, a reagent tube 18 is positioned in the placing grooves 17, a cavity 19 is arranged in the clamping disc 16, the inner wall of the bottom of the cavity 19 is rotatably connected with a rotating shaft 20, the outer wall of the rotating shaft 20 is fixedly sleeved with a rotating disc 21, a plurality of arc-shaped sliding grooves 22 are arranged in the rotating disc 21, a plurality of rectangular grooves 25 are arranged on the outer wall of the clamping disc 16, sliding rods 23 penetrate through the inner walls of one sides of the plurality of rectangular grooves 25, the ends of the plurality of sliding rods 23 close to each other extend into the cavity 19, the tops of the sliding rods 23 are fixedly connected with convex blocks 24 matched with the arc-shaped sliding grooves 22 through bolts, a second spring 26 positioned in the rectangular grooves 25 is sleeved on the outer wall of the sliding rods 23, one end of the sliding rod 23 far away from the cavity 19 is fixedly connected with a clamping plate 27 contacted with the reagent tube 18 through the bolts, and two ends of the second spring 26 are respectively and fixedly connected with the inner walls of one sides of the clamping plate 27 and the rectangular grooves 25, one side fixedly connected with that cavity 19 is kept away from to splint 27 and arc wedge 29 matched with wedge 28, the top fixedly connected with of slide 14 two dead levers 31 with kit 1 sliding connection, and the top of dead lever 31 touches with the bottom of apron 4, when slide 14 upwards moves, trapezoidal piece 43 breaks away from connecting block 45, slide box 32 can pop out from kit 1 under the spring action of third spring 35, and then can pop out slide box 32 from kit 1 when opening kit 1 and making arc 13 shift up, make things convenient for the patient to take out collection cotton stick 33 and carry out gene collection.
In the invention, in the process that the clamping disc 16 is driven by the sliding plate 14 to move upwards, the arc wedge plate 29 gradually releases the brake on the wedge block 28, the wedge block 28 and the clamping plate 27 move outwards under the action of the elastic force of the second spring 26, so that the fixing of the reagent tube 18 is released, the reagent tube 18 is conveniently taken out of the clamping disc 16, and on the contrary, the reagent tube 18 can be fixed through the clamping plate 27 in the process of rotating the cover plate 4 to close the reagent kit 1.
According to the invention, the rotating assembly comprises a limiting block 37 and a fixed cross bar 39 which are fixedly connected to the top of the sliding plate 14, a gear 36 is fixedly sleeved on the outer wall of the rotating shaft 15, a metal rack 38 meshed with the gear 36 is arranged at the top of the sliding plate 14, a sliding block 41 is fixedly connected to one side, close to the metal rack 38, of the fixed cross bar 39 through a bolt, a rectangular sliding groove 40 in sliding fit with the sliding block 41 is arranged on one side, far away from the gear 36, of the metal rack 38, when the metal rack 38 is sucked out of the reagent kit 1 through a magnet 48, the metal rack 38 can be pulled outwards quickly through manpower, the clamping disc 16 is driven to rotate quickly, and then reagents and genes in the reagent tube 18 can be mixed without shaking the reagent tube 18 back and forth through the manpower.
According to the invention, the control assembly comprises a transverse plate 34 fixedly connected to the inner wall of the bottom of the kit 1, the transverse plate 34 is elastically connected with the sliding box 32 through a plurality of third springs 35, a plurality of cotton collecting sticks 33 are arranged in the sliding box 32, one side of the sliding box 32 close to the transverse plate 34 is fixedly connected with a connecting block 45 through bolts, the bottom of the sliding plate 14 is provided with a sliding groove 42, a trapezoidal block 43 extending into the connecting block 45 is slidably connected in the sliding groove 42, the top end of the trapezoidal block 43 is fixedly connected with a fourth spring 44, and the top end of the fourth spring 44 is fixedly connected with the inner wall of the top of the sliding groove 42.
In the invention, one side of the clamping plate 27 close to the rotating shaft 20 is fixedly connected with an arc-shaped pressing block 49 through a bolt, the bottom of the arc-shaped pressing block 49 is contacted with the reagent tube 18, and the reagent tube 18 can be fixed from the upper part through the arc-shaped pressing block 49.
Example 2:
referring to fig. 1-11, a gene diagnosis kit for systemic lupus erythematosus, includes a kit 1 and a plurality of reagent tubes 18 located in the kit 1, the kit 1 is slidably connected with a slide plate 14, the bottom inner wall of the kit 1 is fixedly connected with a plurality of first springs 12, the top ends of the first springs 12 are fixedly connected with the bottom of the slide plate 14, the top of the slide plate 14 is rotatably connected with a rotating shaft 15, the top end of the rotating shaft 15 is fixedly connected with a clamping plate 16 through bolts, the bottom inner wall of the kit 1 is slidably connected with a sliding box 32, the inner walls of the sides of the kit 1 away from each other are fixedly connected with arc wedge plates 29 through bolts, a break groove 30 is arranged in the arc wedge plate 29 on the right side, a fixing component for fixing the reagent tubes 18 is arranged in the clamping plate 16 which is provided with a sealing component capable of sealing the kit 1, the top of the slide plate 14 is provided with a rotating component for driving the clamping plate 16 to rotate, the inner wall of the bottom of the kit 1 is provided with a control component for controlling the sliding of the sliding box 32, one side of the kit 1, which is far away from the support plate 2, is provided with a through hole 51, the metal rack 38 corresponds to the through hole 51, a magnet 48 which is in contact with the metal rack 38 is arranged in the through hole 51, the other end of the magnet 48 is fixedly connected with a touch rod 47 through a bolt, one end of the touch rod 47, which is far away from the metal rack 38, is fixedly connected with a fixed block 46 through a bolt, the bottom end of the fixed block 46 is fixedly connected with the top of the sliding box 32 through a bolt, the metal rack 38 can be taken out of the kit 1 through the magnetic attraction of the magnet 48 to the metal rack 38, the clamping plate 16 is convenient to rotate in the later period, when the touch rod 47 and the magnet 48 are inserted into the through hole 51, the metal rack 38 can be fixed through the matching of the magnet 48 and the limiting block 37, the shaking of the clamping plate 16 is avoided, two arc-shaped grooves 13 which are matched with the arc-shaped wedge plate 29 are arranged in the sliding plate 14, the arc wedge plate 29 just can pass through the arc slot 13 when the sliding plate 14 moves up and down.
In the invention, the closed component comprises two symmetrical support plates 2 fixedly connected to the top of a reagent kit 1 through bolts, one sides of the two support plates 2 close to each other are rotatably connected with a rotating rod 3, the outer wall of the rotating rod 3 is fixedly sleeved with a cover plate 4, the outer wall of the rotating rod 3 is sleeved with two torsion springs 5, the ends of the two torsion springs 5 close to each other are fixedly connected with the cover plate 4, the ends of the two torsion springs 5 far away from each other are respectively fixedly connected with the support plates 2, the top of the reagent kit 1 is provided with a first groove 7, the bottom of the cover plate 4 is fixedly connected with a fixing lug 6 extending into the first groove 7 through the bolts, one side of the reagent kit 1 is provided with a second groove 8, the inner wall of one side of the second groove 8 close to the support plate 2 is provided with a pin 9 in a sliding way, one end of the pin 9 close to the support plate 2 extends into the fixing lug 6, and the other end of the pin 9 is fixedly connected with a fixing plate 10 positioned in the second groove 8 through the bolts, the outer wall cover of round pin 9 is equipped with the extension spring 11 with fixed plate 10 fixed connection, and the other end of extension spring 11 and the one side inner wall fixed connection that second recess 8 is close to backup pad 2.
In the invention, the fixing component comprises a plurality of placing grooves 17 arranged in a clamping disc 16, a reagent tube 18 is positioned in the placing grooves 17, a cavity 19 is arranged in the clamping disc 16, the inner wall of the bottom of the cavity 19 is rotatably connected with a rotating shaft 20, the outer wall of the rotating shaft 20 is fixedly sleeved with a rotating disc 21, a plurality of arc-shaped sliding grooves 22 are arranged in the rotating disc 21, a plurality of rectangular grooves 25 are arranged on the outer wall of the clamping disc 16, sliding rods 23 penetrate through the inner walls of one sides of the plurality of rectangular grooves 25, the ends of the plurality of sliding rods 23 close to each other extend into the cavity 19, the tops of the sliding rods 23 are fixedly connected with convex blocks 24 matched with the arc-shaped sliding grooves 22 through bolts, a second spring 26 positioned in the rectangular grooves 25 is sleeved on the outer wall of the sliding rods 23, one end of the sliding rod 23 far away from the cavity 19 is fixedly connected with a clamping plate 27 contacted with the reagent tube 18 through the bolts, and two ends of the second spring 26 are respectively and fixedly connected with the inner walls of one sides of the clamping plate 27 and the rectangular grooves 25, one side fixedly connected with that cavity 19 is kept away from to splint 27 and arc wedge 29 matched with wedge 28, the top fixedly connected with of slide 14 two dead levers 31 with kit 1 sliding connection, and the top of dead lever 31 touches with the bottom of apron 4, when slide 14 upwards moves, trapezoidal piece 43 breaks away from connecting block 45, slide box 32 can pop out from kit 1 under the spring action of third spring 35, and then can pop out slide box 32 from kit 1 when opening kit 1 and making arc 13 shift up, make things convenient for the patient to take out collection cotton stick 33 and carry out gene collection.
In the invention, in the process that the clamping disc 16 is driven by the sliding plate 14 to move upwards, the arc wedge plate 29 gradually releases the brake on the wedge block 28, the wedge block 28 and the clamping plate 27 move outwards under the action of the elastic force of the second spring 26, so that the fixing of the reagent tube 18 is released, the reagent tube 18 is conveniently taken out of the clamping disc 16, and on the contrary, the reagent tube 18 can be fixed through the clamping plate 27 in the process of rotating the cover plate 4 to close the reagent kit 1.
According to the invention, the rotating assembly comprises a limiting block 37 and a fixed cross bar 39 which are fixedly connected to the top of the sliding plate 14, a gear 36 is fixedly sleeved on the outer wall of the rotating shaft 15, a metal rack 38 meshed with the gear 36 is arranged at the top of the sliding plate 14, a sliding block 41 is fixedly connected to one side, close to the metal rack 38, of the fixed cross bar 39 through a bolt, a rectangular sliding groove 40 in sliding fit with the sliding block 41 is arranged on one side, far away from the gear 36, of the metal rack 38, when the metal rack 38 is sucked out of the reagent kit 1 through a magnet 48, the metal rack 38 can be manually pulled outwards quickly, the clamping disc 16 is driven to rotate quickly, and then reagents and genes in the reagent tube 18 can be mixed without manually shaking the reagent tube 18 back and forth.
According to the invention, the control component comprises a transverse plate 34 fixedly connected to the inner wall of the bottom of the kit 1, the transverse plate 34 is elastically connected with the sliding box 32 through a plurality of third springs 35, a plurality of cotton collecting sticks 33 are arranged in the sliding box 32, one side of the sliding box 32 close to the transverse plate 34 is fixedly connected with a connecting block 45 through bolts, the bottom of the sliding plate 14 is provided with a sliding groove 42, a trapezoidal block 43 extending into the connecting block 45 is slidably connected in the sliding groove 42, the top end of the trapezoidal block 43 is fixedly connected with a fourth spring 44, and the top end of the fourth spring 44 is fixedly connected with the inner wall of the top of the sliding groove 42.
In the invention, one side of the clamping plate 27 close to the rotating shaft 20 is fixedly connected with an arc-shaped pressing block 49 through a bolt, the bottom of the arc-shaped pressing block 49 is contacted with the reagent tube 18, and the reagent tube 18 can be fixed from the upper part through the arc-shaped pressing block 49.
In the present invention, a plurality of slide rods 50 are fixedly connected to the inner wall of the bottom of the reagent cartridge 1 by bolts, the top ends of the slide rods 50 slidably penetrate the slide plate 14, and the slide plate 14 can be guided by the slide rods 50 when the slide plate 14 slides.
The use method of the gene diagnosis kit for systemic lupus erythematosus comprises the following steps:
s1, pulling the fixing plate 10 and the pin 9 outwards, separating the pin 9 from the fixing lug 6, stretching the tension spring 11, keeping the torsion spring 5 in a power storage state, keeping the first spring 12 and the second spring 26 in a compression state, and after the pin 9 releases the brake on the fixing lug 6, starting the cover plate 4 to rotate anticlockwise, so as to open the reagent box 1;
s2, when the cover plate 4 rotates anticlockwise, the sliding plate 14 slides upwards under the action of the elastic force of the first spring 12, the sliding plate 14 drives the clamping disc 16 to slide upwards, when the sliding plate 14 slides, the arc wedge plate 29 can pass through the sliding plate 14, the clamping disc 16 is separated from the two arc wedge plates 29, after the wedge block 28 loses the blocking of the arc wedge plate 29, the wedge block 28, the clamping plate 27 and the sliding rod 23 slide outwards under the action of the elastic force of the second spring 26, and under the matching of the arc sliding groove 22 and the convex block 24, the rotary disc 21 starts to rotate clockwise, so that the clamping plates 27 simultaneously release the clamping of the reagent tubes 18, and the clamping disc 16 is separated from the reagent kit 1;
s3, when the slide plate 14 moves upward, the slide box 32 is firstly abutted by hand to temporarily fix the slide box 32, after the slide plate 14 moves a certain distance, the metal rack 38 and the magnet 48 are staggered to release the abutment on the slide box 32, and the trapezoidal block 43 is already separated from the connecting block 45, because the third spring 35 is always in a compressed state before, the slide box 32 slides to the outside of the reagent kit 1 under the elastic force of the third spring 35, the slide box 32 slides to the outside of the reagent kit 1, and the fixed block 46 and the abutting rod 47 are simultaneously separated from the inside of the reagent kit 1;
s4, taking out the collecting cotton swab 33 from the sliding box 32, dipping the genes from the systemic lupus erythematosus through the collecting cotton swab 33, inserting the genes dipped by the collecting cotton swab 33 into the reagent tube 18, mixing the reagent in the reagent tube 18 with the systemic lupus erythematosus genes, dipping a plurality of groups of genes, and respectively inserting the genes into the reagent tube 18;
s5, reinserting the reagent tube 18 mixed with the gene and the reagent into the placing groove 17, reversely rotating the cover plate 4, and reclosing the reagent kit 1, wherein when the cover plate 4 rotates clockwise, the cover plate 4 pushes the fixing rod 31 to enable the sliding plate 14 and the clamping disc 16 to move downwards again, the first spring 12 starts to compress, in the downward movement process of the clamping disc 16, the clamping plates 27 and the sliding rod 23 can move towards the middle due to the matching of the arc-shaped wedge plate 29 and the wedge block 28, the second spring 26 starts to compress, further the rotary disc 21 rotates anticlockwise under the action of the arc-shaped sliding groove 22 and the convex block 24, and meanwhile, the clamping plates 27 clamp and fix the reagent tube 18 respectively;
s6, the sliding box 32 and the fixing block 46 are pushed to slide towards the inner wall of the reagent box 1, the abutting rod 47 and the magnet 48 extend into the reagent box 1, the magnet 48 can be close to the metal rack 38, the bottom end of the trapezoidal block 43 is in contact with the top of one side of the connecting block 45 at the moment, the trapezoidal block 43 cannot extend into the connecting block 45, the magnetic attraction of the magnet 48 to the metal rack 38 is large enough, the metal rack 38 can be sucked out of the reagent box 1, then the metal rack 38 is pulled outwards quickly by manpower, due to the fact that the gear 36 is meshed with the metal rack 38, in the process that the metal rack 38 slides outwards, the metal rack 38 drives the rotating shaft 15 and the clamping plate 16 to rotate quickly through the gear 36, the reagent tube 18 can be driven to rotate, and reagents in the reagent tube 18 are fully mixed with genes;
s7, after reagent in the reagent tube 18 and gene intensive mixing are completed, the sliding box 32 and the fixing block 46 are pushed towards the inside of the reagent box 1, the connecting block 45 extends into the reagent box 1 under the driving of the sliding box 32, the trapezoidal block 43 extends into the connecting block 45 again under the matching of the trapezoidal block 43 and the fourth spring 44 to clamp the sliding box 32, the magnet 48 can push the metal rack 38 to move towards the direction of the limiting block 37, and then the cooperation of the magnet 48 and the limiting block 37 can fix the metal rack 38, so that the rotation of the clamping plate 16 when the reagent box 1 shakes is avoided.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be able to cover the technical scope of the present invention and the equivalent alternatives or modifications according to the technical solution and the inventive concept of the present invention within the technical scope of the present invention.
Claims (10)
1. A gene diagnosis kit for systemic lupus erythematosus comprises a kit (1) and a plurality of reagent tubes (18) positioned in the kit (1), and is characterized in that a sliding plate (14) is connected in the kit (1) in a sliding manner, the inner wall of the bottom of the kit (1) is fixedly connected with a plurality of first springs (12), the top ends of the first springs (12) are fixedly connected with the bottom of the sliding plate (14), the top of the sliding plate (14) is rotatably connected with a rotating shaft (15), the top end of the rotating shaft (15) is fixedly connected with a clamping plate (16), the inner wall of the bottom of the kit (1) is connected with a sliding box (32) in a sliding manner, the inner wall of one side, far away from each other, of the kit (1) is fixedly connected with an arc wedge plate (29), and a broken groove (30) is arranged in the arc wedge plate (29) positioned on the right side;
a sealing component capable of sealing the kit (1) is arranged in the kit (1);
a fixing component for fixing the reagent tube (18) is arranged in the clamping plate (16);
the top of the sliding plate (14) is provided with a rotating assembly for driving the clamping disc (16) to rotate;
the inner wall of the bottom of the kit (1) is provided with a control component for controlling the sliding of the sliding box (32).
2. The gene diagnostic kit for systemic lupus erythematosus according to claim 1, the sealing component comprises two symmetrical supporting plates (2) fixedly connected to the top of the kit (1), one side of each supporting plate (2) close to each other is rotatably connected with a rotating rod (3), the outer wall of the rotating rod (3) is fixedly sleeved with a cover plate (4), the outer wall of the rotating rod (3) is sleeved with two torsion springs (5), one ends of the two torsion springs (5) close to each other are fixedly connected with the cover plate (4), the other ends of the two torsion springs (5) far away from each other are respectively fixedly connected with the supporting plate (2), the top of kit (1) is equipped with first recess (7), the bottom fixedly connected with of apron (4) extends to fixed ear (6) in first recess (7).
3. The gene diagnostic kit for systemic lupus erythematosus as claimed in claim 1, wherein the fixing assembly comprises a plurality of placing grooves (17) disposed in a holding plate (16), and a reagent tube (18) is disposed in the placing grooves (17), a cavity (19) is disposed in the holding plate (16), a rotating shaft (20) is rotatably connected to the bottom inner wall of the cavity (19), a rotating plate (21) is fixedly sleeved on the outer wall of the rotating shaft (20), a plurality of arc-shaped sliding grooves (22) are disposed in the rotating plate (21), a plurality of rectangular grooves (25) are disposed on the outer wall of the holding plate (16), a sliding rod (23) penetrates through the inner wall of one side of the plurality of rectangular grooves (25) adjacent to each other in a sliding manner, one ends of the plurality of sliding rods (23) adjacent to each other extend into the cavity (19), and a bump (24) matched with the arc-shaped sliding grooves (22) is fixedly connected to the top of the sliding rods (23), and a second spring (26) positioned in the rectangular groove (25) is sleeved on the outer wall of the sliding rod (23).
4. The gene diagnosis kit for systemic lupus erythematosus as claimed in claim 1, wherein the rotating assembly comprises a limiting block (37) and a fixed cross bar (39) which are fixedly connected to the top of the sliding plate (14), a gear (36) is fixedly sleeved on the outer wall of the rotating shaft (15), a metal rack (38) meshed with the gear (36) is arranged on the top of the sliding plate (14), a sliding block (41) is fixedly connected to one side of the fixed cross bar (39) close to the metal rack (38), and a rectangular sliding groove (40) in sliding fit with the sliding block (41) is arranged on one side of the metal rack (38) far away from the gear (36).
5. The gene diagnosis kit for systemic lupus erythematosus as claimed in claim 1, wherein the control assembly comprises a transverse plate (34) fixedly connected to the inner wall of the bottom of the kit (1), the transverse plate (34) and a sliding box (32) are elastically connected through a plurality of third springs (35), a plurality of cotton collecting sticks (33) are arranged in the sliding box (32), a connecting block (45) is fixedly connected to one side of the sliding box (32) close to the transverse plate (34), a sliding groove (42) is arranged at the bottom of the sliding plate (14), a trapezoidal block (43) extending into the connecting block (45) is slidably connected in the sliding groove (42), a fourth spring (44) is fixedly connected to the top end of the trapezoidal block (43), and the top end of the fourth spring (44) is fixedly connected to the inner wall of the top of the sliding groove (42).
6. The gene diagnosis kit for systemic lupus erythematosus as claimed in claim 1, wherein a through hole (51) is provided at one side of the kit (1) away from the support plate (2), the metal rack (38) corresponds to the through hole (51), a magnet (48) which is in contact with the metal rack (38) is provided in the through hole (51), a contact rod (47) is fixedly connected to the other end of the magnet (48), a fixing block (46) is fixedly connected to one end of the contact rod (47) away from the metal rack (38), and the bottom end of the fixing block (46) is fixedly connected to the top of the sliding box (32).
7. The gene diagnosis kit for systemic lupus erythematosus as claimed in claim 2, wherein the sealing member further comprises a second groove (8) disposed at one side of the kit (1), a pin (9) slidably penetrates through an inner wall of one side of the second groove (8) close to the support plate (2), one end of the pin (9) close to the support plate (2) extends into the fixing lug (6), the other end of the pin (9) is fixedly connected with a fixing plate (10) located in the second groove (8), an extension spring (11) fixedly connected with the fixing plate (10) is sleeved on an outer wall of the pin (9), and the other end of the extension spring (11) and the inner wall of one side of the second groove (8) close to the support plate (2) are fixedly connected.
8. The gene diagnostic kit for systemic lupus erythematosus according to claim 3, the fixing component also comprises a clamping plate (27) which is fixedly connected with one end of the sliding rod (23) far away from the cavity (19) and is contacted with the reagent tube (18), two ends of the second spring (26) are respectively fixedly connected with the clamping plate (27) and the inner wall of one side of the rectangular groove (25), one side of the clamping plate (27) far away from the cavity (19) is fixedly connected with a wedge-shaped block (28) matched with the arc-shaped wedge plate (29), the top of the sliding plate (14) is fixedly connected with two fixed rods (31) which are in sliding connection with the reagent kit (1), the top end of the fixing rod (31) is in contact with the bottom of the cover plate (4), one side of the clamping plate (27) close to the rotating shaft (20) is fixedly connected with an arc-shaped pressing block (49), and the bottom of the arc-shaped pressing block (49) is in contact with the reagent tube (18).
9. The gene diagnosis kit for systemic lupus erythematosus of claim 1, wherein two arc-shaped grooves (13) matched with the arc-shaped wedge plates (29) are formed in the sliding plate (14), a plurality of sliding rods (50) are fixedly connected to the inner wall of the bottom of the kit (1), and the top ends of the sliding rods (50) penetrate through the sliding plate (14) in a sliding manner.
10. The use method of the gene diagnostic kit for systemic lupus erythematosus according to any one of claims 1 to 9, characterized by comprising the steps of:
s1, pulling the fixing plate (10) and the pin (9) outwards, separating the pin (9) from the fixing lug (6), stretching the tension spring (11), keeping the torsion spring (5) in a force storage state before, keeping the first spring (12) and the second spring (26) in a compression state, and opening the reagent box (1) after the pin (9) releases the brake on the fixing lug (6) and the cover plate (4) starts to rotate anticlockwise;
s2, when the cover plate (4) rotates anticlockwise, the sliding plate (14) slides upwards under the action of the elastic force of the first spring (12), the sliding plate (14) drives the clamping disc (16) to slide upwards, when the sliding plate (14) slides, the arc wedge plate (29) can penetrate through the sliding plate (14), the clamping disc (16) is separated from the two arc wedge plates (29), after the wedge block (28) loses the blocking of the arc wedge plates (29), the wedge block (28), the clamping plate (27) and the sliding rod (23) slide outwards under the action of the elastic force of the second spring (26), and under the matching of the arc sliding chute (22) and the convex block (24), the rotary disc (21) starts to rotate clockwise, so that the clamping plates (27) simultaneously release the clamping of the reagent tubes (18), and the clamping disc (16) is separated from the reagent kit (1);
s3, when the sliding plate (14) moves upwards, firstly, the sliding box (32) is abutted by hands, so that the sliding box (32) is temporarily fixed, after the sliding plate (14) moves for a certain distance, the metal rack (38) and the magnet (48) are staggered, the abutment on the sliding box (32) is released, the trapezoidal block (43) is already separated from the connecting block (45), the sliding box (32) slides to the outer side of the reagent kit (1) under the action of the elastic force of the third spring (35) because the third spring (35) is always in a compressed state, the sliding box (32) slides to the outer side of the reagent kit (1), and the fixed block (46) and the abutment rod (47) are separated from the reagent kit (1) at the same time;
s4, taking out the collecting cotton swab (33) from the sliding box (32), dipping the genes from the systemic lupus erythematosus through the collecting cotton swab (33), inserting the genes dipped by the collecting cotton swab (33) into a reagent tube (18), mixing the reagent in the reagent tube (18) with the systemic lupus erythematosus genes, dipping a plurality of groups of genes, and respectively inserting the genes into the reagent tube (18);
s5, reinserting the reagent tube (18) mixed with the gene and the reagent into the placing groove (17), reversely rotating the cover plate (4), and reclosing the reagent box (1), wherein when the cover plate (4) rotates clockwise, the cover plate (4) pushes the fixing rod (31) to enable the sliding plate (14) and the clamping disc (16) to move downwards again, the first spring (12) starts to compress, in the downward movement process of the clamping disc (16), the clamping plate (27) and the sliding rod (23) can move towards the middle through the matching of the arc wedge plate (29) and the wedge block (28), the second spring (26) starts to compress, further, the rotary disc (21) rotates anticlockwise under the action of the arc sliding groove (22) and the bump (24), and meanwhile, the clamping plates (27) clamp and fix the reagent tube (18) respectively;
s6, the sliding box (32) and the fixing block (46) are pushed to slide towards the inner wall of the reagent box (1), the contact rod (47) and the magnet (48) extend into the reagent box (1), the magnet (48) can be close to the metal rack (38), at the moment, the bottom end of the trapezoidal block (43) is contacted with the top of one side of the connecting block (45), the trapezoidal block (43) can not extend into the connecting block (45), the magnetic attraction of the magnet (48) to the metal rack (38) is large enough to suck the metal rack (38) out of the reagent box (1), then the metal rack (38) is pulled outwards rapidly by manpower, because the gear (36) is meshed with the metal rack (38), and in the process that the metal rack (38) slides outwards, the metal rack (38) drives the rotating shaft (15) and the clamping disc (16) to rotate rapidly through the gear (36), and then the reagent tube (18) can be driven to rotate;
s7, after the reagent in the reagent tube (18) is fully mixed with the gene, the sliding box (32) and the fixing block (46) are pushed towards the inside of the reagent box (1), the connecting block (45) extends into the reagent box (1) under the driving of the sliding box (32), the trapezoidal block (43) extends into the connecting block (45) again to clamp the sliding box (32) under the matching of the trapezoidal block (43) and the fourth spring (44), and the magnet (48) can push the metal rack (38) to move towards the direction of the limiting block (37).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210597789.8A CN114955241A (en) | 2022-05-30 | 2022-05-30 | Gene diagnosis kit for systemic lupus erythematosus and use method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210597789.8A CN114955241A (en) | 2022-05-30 | 2022-05-30 | Gene diagnosis kit for systemic lupus erythematosus and use method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN114955241A true CN114955241A (en) | 2022-08-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210597789.8A Pending CN114955241A (en) | 2022-05-30 | 2022-05-30 | Gene diagnosis kit for systemic lupus erythematosus and use method thereof |
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| CN (1) | CN114955241A (en) |
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| CN115447895A (en) * | 2022-10-21 | 2022-12-09 | 广西金域医学检验实验室有限公司 | Warehouse reagent management system |
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