CN114939139B - A Chinese medicinal composition for treating osteoarthropathy, and its preparation method - Google Patents
A Chinese medicinal composition for treating osteoarthropathy, and its preparation method Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating bone joint diseases and a preparation method thereof, wherein the traditional Chinese medicine composition for treating bone joint diseases comprises the following components: radix Aconiti Kusnezoffii Preparata, radix Aconiti Preparata, rhizoma Ligustici Chuanxiong, caulis Spatholobi, radix Dipsaci, radix Paeoniae Rubra, notopterygii rhizoma, olibanum, myrrha, radix astragali, radix rehmanniae Preparata, herba Taxilli, carthami flos, eucommiae cortex, achyranthis radix, and Eupolyphaga Seu Steleophaga. The traditional Chinese medicine composition for treating the bone joint diseases can be used for treating symptoms such as general joint acid, numbness, wood, distension and pain of a human body, is a plurality of traditional Chinese medicine optimized formulas, effectively treats hyperosteogeny, protrusion of cervical and lumbar intervertebral discs, distension and lumbar spinal stenosis and the like in clinical treatment, and has the characteristics of short curative effect, quick response, low cost, no side effect, no recurrence and the like.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating bone joint diseases and a preparation method thereof.
Background
The root cause of the osteoarthropathy, including degenerative arthritis, bursitis, synovitis, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, rheumatic arthritis, rheumatoid arthritis, femoral head necrosis and the like, is not that bones are diseased, and the modern medical research finds that the root of the osteoarthropathy is the loss of joint protection capability of the joint protection system, such as cartilage and the like. Patients with bone joint disease are lightly painful and uncomfortable, heavily restricted in movement or need to be bedridden for maintenance. The traditional Chinese medicine has a certain traditional Chinese medicine treatment medicine and method for the osteoarthropathy, which are called as arthralgia, but the treatment course is longer and the effect is slower.
Disclosure of Invention
The invention aims to solve the technical problems of long treatment course and slow effect of the medicine for treating the bone joint diseases in the prior art.
In order to solve the technical problems, the technical scheme of the invention is as follows:
a traditional Chinese medicine composition for treating bone joint diseases, comprising: radix Aconiti Kusnezoffii Preparata, radix Aconiti Preparata, rhizoma Ligustici Chuanxiong, caulis Spatholobi, radix Dipsaci, radix Paeoniae Rubra, notopterygii rhizoma, olibanum, myrrha, radix astragali, radix rehmanniae Preparata, herba Taxilli, carthami flos, eucommiae cortex, achyranthis radix, and Eupolyphaga Seu Steleophaga.
Preferably, the traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
300-900 parts of prepared kusnezoff monkshood root; 300-900 parts of prepared radix aconiti; 600-1500 parts of ligusticum wallichii; 900-1500 parts of spatholobus stem; 600-1500 parts of teasel root; 600-1500 parts of red paeony root; 600-1500 parts of notopterygium root; 600-1500 parts of frankincense; 600-1500 parts of myrrh; 900-2000 parts of astragalus; 900-1500 parts of prepared rehmannia root; 900-1500 parts of mistletoe; 600-1200 parts of safflower; 600-1200 parts of eucommia ulmoides; 600-1500 parts of achyranthes root; 600-1200 parts of ground beetle.
Preferably, the traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle.
Preferably, the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
Preferably, the traditional Chinese medicine composition for treating bone joint diseases further comprises 900-1500 parts of garden balsam stem.
Preferably, the traditional Chinese medicine composition for treating bone joint diseases further comprises 900-1500 parts of lycopodium clavatum.
Preferably, the traditional Chinese medicine composition for treating bone joint diseases also comprises 20-30 parts by weight of veratrum.
The invention also provides a preparation method of the traditional Chinese medicine composition for treating the bone joint diseases, which comprises the following steps: mixing radix Aconiti Kusnezoffii Preparata, radix Aconiti Preparata, rhizoma Ligustici Chuanxiong, caulis Spatholobi, radix Dipsaci, radix Paeoniae Rubra, notopterygii rhizoma, olibanum, myrrha, radix astragali, radix rehmanniae Preparata, herba Taxilli, carthami flos, eucommiae cortex, achyranthis radix, and Eupolyphaga Seu Steleophaga, and making into clinically acceptable preparation.
Preferably, the preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases of powder.
Preferably, the preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200 meshes of powder, sieved and uniformly mixed to prepare the traditional Chinese medicine composition for treating the bone joint diseases.
Preferably, the preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to prepare the traditional Chinese medicine composition for treating the osteoarthropathy of the water-honeyed pill.
The scheme of the invention at least comprises the following beneficial effects:
(1) The invention relates to a traditional Chinese medicine composition for treating bone joint diseases, which comprises the following components: radix Aconiti Kusnezoffii Preparata, radix Aconiti Preparata, rhizoma Ligustici Chuanxiong, caulis Spatholobi, radix Dipsaci, radix Paeoniae Rubra, notopterygii rhizoma, olibanum, myrrha, radix astragali, radix rehmanniae Preparata, herba Taxilli, carthami flos, eucommiae cortex, achyranthis radix, and Eupolyphaga Seu Steleophaga. The traditional Chinese medicine composition for treating the bone joint diseases can be used for treating symptoms such as general joint acid, numbness, wood, swelling and pain of a human body, is a plurality of traditional Chinese medicine optimized formulas, effectively treats the bone joint diseases such as hyperosteogeny, protrusion of cervical and lumbar intervertebral discs, swelling, cervical and lumbar spinal stenosis, osteoarthritis and the like in clinical treatment, and has the characteristics of short curative effect, quick response, low cost, no side effect, no recurrence and the like. Wherein:
radix Aconiti Kusnezoffii Preparata, pungent and bitter in flavor, and warm in nature, enters heart, liver, kidney and spleen meridians. Has effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain, and can be used for treating arthralgia due to wind-cold-dampness, arthralgia, and pain due to heart and abdomen, and cold hernia.
Processed Chuan Wu is pungent and bitter in flavor, and is toxic in nature and enters heart, liver, kidney and spleen meridians. Has effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain, and can be used for treating arthralgia due to wind-cold-dampness, breast pain, chest pain, joint pain, cold pain of heart and abdomen, cold hernia pain, and anesthesia and pain.
Chuan Xiong, pungent in flavor, warm in nature, enters liver and gallbladder meridians. Has effects in activating qi-flowing, resolving stagnation, dispelling pathogenic wind, removing dampness, promoting blood circulation, and relieving pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, chest and hypochondrium pain, traumatic injury, headache, and rheumatalgia.
Caulis Spatholobi is bitter and slightly sweet in taste and warm in nature, and enters liver, heart and kidney meridians. It has effects of promoting blood circulation, relaxing muscles and tendons, nourishing blood, and regulating menstruation, and can be used for treating rheumatalgia, numbness of limbs, paralysis of limbs, menoxenia, unsmooth menstruation, dysmenorrhea, amenorrhea, and leukopenia.
Radix dipsaci, slightly warm in nature, bitter and pungent in flavor, enter liver and kidney meridians. Has effects of nourishing liver and kidney, strengthening tendons and bones, relieving fracture and injury, and can be used for treating liver and kidney deficiency, soreness and weakness of waist and knee, rheumatalgia, tendons injury fracture, metrorrhagia, fetal leakage, traumatic injury, etc.
Red peony root, radix Paeoniae Rubra, bitter in flavor, slightly cold in nature, enters liver meridian. Has effects in nourishing yin, removing blood stasis, relieving pain, cooling blood, and relieving swelling, and can be used for treating amenorrhea due to blood stasis, abdominal pain, hypochondriac pain, epistaxis, bloody dysentery, intestinal wind, blood stasis, conjunctival congestion, carbuncle, and traumatic injury.
Qiang Huo is pungent and bitter in flavor and warm in nature, enters bladder and kidney meridians. Has effects of dispelling exterior cold, dispelling pathogenic wind and dampness, benefiting articulation, and relieving pain, and can be used for treating wind cold, headache without sweat, oil-printed cold-dampness arthralgia, edema of wind-water, and pyocutaneous disease.
Boswellia is pungent and bitter in flavor, warm in nature, entering heart, liver and spleen meridians. Has effects of regulating qi and promoting blood circulation, relieving pain, and removing toxic substances, and can be used for treating stagnation of qi and blood, heart and abdomen pain, carbuncle, sore, toxic swelling, traumatic injury, dysmenorrhea, puerperal blood stasis and pricking pain.
Myrrh, bitter in taste, neutral in nature and nontoxic. Has effects of dispelling blood stasis, relieving swelling and pain, and can be used for treating traumatic injury, sore, tendons and bones, pain in heart and abdomen, abdominal mass, amenorrhea, carbuncle, swelling and pain, anal fistula, and eye obstacle.
Huang Qi is sweet in flavor and slightly warm in nature, and enters lung, spleen, liver and kidney meridians. Has effects of invigorating and consolidating superficial resistance, and promoting granulation, and can be used for treating spontaneous perspiration due to asthenia, chronic diarrhea, rectocele, uterine prolapse, chronic nephritis, edema due to asthenia, chronic ulcer, and chronic sore.
Prepared rhizome of rehmannia, radix rehmanniae, sweet in flavor, slightly warm in nature, enters liver and kidney meridians. Has effects of replenishing blood, nourishing yin, replenishing essence, and nourishing marrow, and can be used for treating yin deficiency fever, diabetes, hematemesis, epistaxis, metrorrhagia, menoxenia, fetal movement anxiety, and constipation due to yin injury.
Loranthus mulberry mistletoe, herba Taxilli, bitter in flavor, sweet in flavor, and neutral in nature, enters liver and kidney meridians. Has effects in nourishing liver and kidney, strengthening tendons and bones, eliminating rheumatism, dredging channels and collaterals, tonifying blood, and preventing miscarriage, and can be used for treating soreness of waist and knees, tendons and bones debility, tinea pedis, arthralgia due to wind-cold-dampness, metrorrhagia, puerperal galactostasis, chronic cough, and longitudinal vertigo.
Safflower, carthami flos, with pungent taste, warm nature, enters heart and liver meridians. Has effects of dredging channels and promoting blood circulation, and can be used for treating female diseases.
Eucommia ulmoides is warm in nature and sweet in taste, and enters liver meridian and kidney meridian. Has effects in nourishing liver and kidney, strengthening tendons and bones, and preventing miscarriage, and can be used for treating lumbago due to kidney deficiency, weakness of tendons and bones, blood leakage of pregnancy, fetal movement disorder, and hypertension.
Achyranthes root, radix Achyranthis bidentatae, bitter in taste, sour, neutral in nature, enters liver and kidney meridians. Has effects in nourishing liver and kidney, strengthening tendons and bones, dispelling blood stasis, dredging channels, and promoting blood circulation, and can be used for treating soreness of waist and knees, weakness of tendons and bones, amenorrhea, and dizziness due to liver yang.
Eupolyphaga Seu Steleophaga is salty in taste, cold in nature, and has little toxicity, and enters liver meridian. Has effects of removing blood stasis and promoting reunion of bones and muscles, and can be used for treating fracture injury of tendons and bones, amenorrhea due to blood stasis, and abdominal mass.
For the symptoms of 'arthralgia' in traditional Chinese medicine, namely wind-cold-dampness evil invades the body when the vital energy is insufficient and the defensive qi is deficient, and the evil invades the body to cause pain caused by blockage of channels and collaterals, among the components, the prepared kusnezoff monkshood root and prepared common monkshood mother root jointly play a role in warming channels and relieving pain, the szechuan lovage rhizome and the suberect spatholobus stem jointly play a role in promoting blood circulation and relieving pain, the red paeony root and the myrrh jointly play a role in detumescence and relieving pain, the teasel root, the mistletoe, the eucommia bark and the achyranthes root jointly play a role in nourishing liver and kidney and strengthening tendons and bones, the notopterygium root plays a role in dispelling exterior cold, the frankincense and safflower jointly play a role in regulating qi and promoting blood circulation, the astragalus root and promoting granulation, the ground beetle continues tendons and bones, and the prepared rehmannia root enriches blood and nourishes yin. The components have comprehensive effects, have obvious relieving effects on symptoms of pain discomfort and limited movement of the bone joint diseases, and have comprehensive regulating effects on qi and blood circulation in vivo and the like, so that the treatment effect of both principal and secondary aspects of the disease is achieved, and the treatment course is greatly shortened.
(2) The invention relates to a traditional Chinese medicine composition for treating bone joint diseases, which also comprises 900-1500 parts of garden balsam stem and 900-1500 parts of lycopodium clavatum. Herba speranskiae tuberculatae, sweet and pungent in flavor, warm in nature, enters lung and liver meridians, and has the effects of activating blood circulation to dissipate blood stasis, promoting urination and removing toxicity, and dredging meridians and bone. Bitter in flavor, pungent in property and warm in nature, enters liver meridian, has the effects of dispelling wind and cold, removing dampness and detumescence, and relaxing tendons and activating collaterals, and can be used for wind-cold-dampness arthralgia, spasm pain and carbuncle of tendons and vessels, and swelling and pain caused by traumatic injury and sprain. The speranskia herb and the lycopodium clavatum have the effects of dispelling wind, dispelling cold and eliminating dampness together so as to treat bone joint diseases invaded by exogenous evil.
(3) The invention relates to a traditional Chinese medicine composition for treating bone joint diseases, which also comprises 20-30 parts by weight of veratrum. The veratrum is pungent and bitter in taste, cold in nature and toxic, and is opposite to red paeony root, but a small amount of use can play a role in strengthening bones and muscles, so that the efficacy of the whole formula is remarkably improved, the traditional Chinese medicine composition for treating the bone joint diseases is difficult to exert the efficacy when being used excessively, and certain toxic and side effects can be generated along with the increase of the use amount.
Detailed Description
The specific conditions not noted in the examples of the present invention were carried out according to the conventional conditions or the conditions suggested by the manufacturer. The reagents or instruments used are not marked for manufacturers, are conventional products which can be obtained through commercial purchase, and the implementation of the technical scheme and the realization of the technical effect of the invention are not influenced by raw materials of different manufacturers and models.
Example 1
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
300 parts of prepared kusnezoff monkshood root; 900 parts of prepared radix aconiti; 1050 parts of ligusticum wallichii; 900 parts of spatholobus stem; 1500 parts of teasel root; 1050 parts of red paeony root; 600 parts of notopterygium root; 1500 parts of frankincense; 1000 parts of myrrh; 900 parts of astragalus; 1500 parts of prepared rehmannia root; 1200 parts of mistletoe; 600 parts of safflower; 1200 parts of eucommia ulmoides; 1000 parts of achyranthes root; 600 parts of ground beetle. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases of powder.
As an alternative implementation manner of this embodiment, the traditional Chinese medicine composition for treating bone joint diseases may be prepared into capsules, water-honeyed pills or decoction.
Example 2
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
900 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 600 parts of ligusticum wallichii; 1500 parts of spatholobus stem; 1000 parts of teasel root; 600 parts of red paeony root; 1500 parts of notopterygium root; 1000 parts of frankincense; 600 parts of myrrh; 2000 parts of astragalus; 1200 parts of prepared rehmannia root; 900 parts of mistletoe; 1200 parts of safflower; 900 parts of eucommia ulmoides; 600 parts of achyranthes root; 1200 parts of ground beetle; 900 parts of garden balsam stem; 1500 parts of lycopodium clavatum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases of powder.
Example 3
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 300 parts of prepared radix aconiti; 1500 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 600 parts of teasel root; 1500 parts of red paeony root; 1000 parts of notopterygium root; 600 parts of frankincense; 1500 parts of myrrh; 1500 parts of astragalus; 900 parts of prepared rehmannia root; 1500 parts of mistletoe; 900 parts of safflower; 600 parts of eucommia ulmoides; 1500 parts of achyranthes root; 900 parts of ground beetle. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases of powder.
Example 4
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root and ground beeltle are taken, crushed into 200-mesh powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases of powder.
Example 5
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 900 parts of garden balsam stem; 1500 parts of lycopodium clavatum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem and common clubmoss herb are taken, crushed into 200 meshes of powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases.
Example 6
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1500 parts of garden balsam stem; 900 parts of lycopodium clavatum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem and common clubmoss herb are taken, crushed into 200 meshes of powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases.
Example 7
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1200 parts of garden balsam stem; 1200 parts of lycopodium clavatum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem and common clubmoss herb are taken, crushed into 200 meshes of powder, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating bone joint diseases.
Example 8
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1200 parts of garden balsam stem; 1200 parts of lycopodium clavatum; 20 parts of veratrum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, the powder is crushed into 200 meshes of powder, and the powder is obtained by sieving and uniformly mixing.
Example 9
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1200 parts of garden balsam stem; 1200 parts of lycopodium clavatum; 30 parts of veratrum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, the powder is crushed into 200 meshes of powder, and the powder is obtained by sieving and uniformly mixing.
Example 10
The traditional Chinese medicine composition for treating bone joint diseases comprises the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1200 parts of garden balsam stem; 1200 parts of lycopodium clavatum; 50 parts of veratrum. Wherein the myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
The preparation method of the traditional Chinese medicine composition for treating bone joint diseases comprises the following steps:
according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, the powder is crushed into 200 meshes of powder, and the powder is obtained by sieving and uniformly mixing.
Effect comparative example
In order to verify the technical effects of the traditional Chinese medicine composition for treating bone joint diseases, the following tests are carried out:
(1) Experiment of drug efficacy
200 patients with osteoarthropathy were randomly selected, and 20 patients were grouped into 7 groups, and each group of patients was administered with the Chinese medicinal composition for treating osteoarthropathy obtained in examples 1 to 10, at a dose of 2.58g every 4 hours. Each patient is scored according to the WOMC scoring scale before treatment, two weeks and four weeks of treatment, the scoring condition of each group of patients is counted, the average value of each group of patients before treatment, two weeks and four weeks of treatment is calculated, and the difference value between the WOMC score of each group of patients before treatment and the WOMC score of four weeks of treatment is calculated.
Wherein, the total scoring items of the WOMAC scoring scale are 24, including the bone joint pain degree, difficulty degree and bone joint stiffness degree when each activity is carried out, the score of each item is 0-4, the total score is 0-96, the higher the score is, the more serious the symptom is, and the higher the score is, the more slight the symptom is.
The test results were as follows:
the results show that the traditional Chinese medicine composition for treating the bone joint diseases has obvious medicine effect, and patients can be obviously improved after receiving treatment for two weeks, and the traditional Chinese medicine composition has quick response and short treatment course. According to the comparison of examples 1-4 and examples 5-7, the traditional Chinese medicine composition for treating bone joint diseases can improve the treatment effect when added with garden balsam stem and lycopodium clavatum. As can be seen from the comparison of examples 1-7 and examples 8-10, the traditional Chinese medicine composition for treating bone joint diseases can obviously improve the treatment effect when a small amount of veratrum is added, but can lead to the reduction of the treatment effect when the amount of veratrum is excessive.
(2) Typical cases:
patient 1, men, 6l years old, CT of Tianjin sea hospital confirms lumbar vertebra hyperosteogeny, chest 11-12 to lumbar and sacral facet joint damage, indicating that there is intervertebral disc origin pain in waist 3-5, and fat deposition signal of waist 4 vertebral body changes, orally taking the traditional Chinese medicine composition for treating bone joint diseases described in the embodiment 8 of the invention every 4 hours, taking 2.58g every 4 hours for three times, without adverse reaction of medicine usage, and basically recovering in 2020 12 months after 8 weeks of medicine usage.
Patient 2, woman, 48 years old, the occurrence of lumbago at 44 years old, the established diagnosis is lumbar intervertebral 2-3 protrusion, lumbar vertebra 1-5 hyperosteogeny, patient walk inconvenient, daily bedridden maintenance, oral administration of the traditional Chinese medicine composition for treating bone joint diseases described in example 8 of the invention, every 4 hours, 2.58g, three times daily, no adverse reaction of medication, obvious improvement of symptoms after 2 weeks of medication, CT review after 8 weeks of medication, complete disappearance of hyperosteogeny and lumbar disc herniation, and normal operation.
It will be appreciated by those skilled in the art that the present invention can be carried out in other embodiments without departing from the spirit or essential characteristics thereof. Accordingly, the above disclosed embodiments are illustrative in all respects, and not exclusive. All changes that come within the scope of the invention or equivalents thereto are intended to be embraced therein.
Claims (6)
1. The traditional Chinese medicine composition for treating the bone joint diseases is characterized by being prepared from the following raw materials in parts by weight:
600 parts of prepared kusnezoff monkshood root; 600 parts of prepared radix aconiti; 1000 parts of ligusticum wallichii; 1200 parts of spatholobus stem; 1000 parts of teasel root; 1000 parts of red paeony root; 1000 parts of notopterygium root; 1000 parts of frankincense; 1000 parts of myrrh; 1500 parts of astragalus; 1200 parts of prepared rehmannia root; 1200 parts of mistletoe; 900 parts of safflower; 900 parts of eucommia ulmoides; 1000 parts of achyranthes root; 900 parts of ground beetle; 1200 parts of garden balsam stem; 1200 parts of lycopodium clavatum; 20 parts of veratrum.
2. The traditional Chinese medicine composition for treating osteoarticular diseases according to claim 1, wherein said myrrh is prepared myrrh; the Olibanum is prepared from Olibanum.
3. A method for preparing a traditional Chinese medicine composition for treating bone joint diseases, which is characterized in that the traditional Chinese medicine composition is the traditional Chinese medicine composition according to claim 1 or 2, and comprises the following steps: mixing radix Aconiti Kusnezoffii Preparata, radix Aconiti Preparata, rhizoma Ligustici Chuanxiong, caulis Spatholobi, radix Dipsaci, radix Paeoniae Rubra, notopterygii rhizoma, olibanum, myrrha, radix astragali, radix rehmanniae Preparata, herba Taxilli, carthami flos, eucommiae cortex, achyranthis radix, eupolyphaga Seu Steleophaga, herba Speranskiae Tuberculatae, herba Lycopodii, and rhizoma et radix Veratri, and making into clinically acceptable preparation.
4. The method for preparing a traditional Chinese medicine composition for treating osteoarticular diseases according to claim 3, comprising the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, is crushed into 200-mesh powder, sieved and uniformly mixed to obtain powder.
5. The method for preparing a traditional Chinese medicine composition for treating osteoarticular diseases according to claim 3, comprising the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, is crushed into powder of 200 meshes, sieved, uniformly mixed and prepared into capsules.
6. The method for preparing a traditional Chinese medicine composition for treating osteoarticular diseases according to claim 3, comprising the following steps: according to the selected weight portions, prepared kusnezoff monkshood root, prepared common monkshood mother root, szechuan lovage rhizome, suberect spatholobus stem, himalayan teasel root, red paeony root, incised notopterygium rhizome, frankincense, myrrh, astragalus root, prepared rehmannia root, mistletoe, safflower, eucommia bark, twotooth achyranthes root, ground beeltle, garden balsam stem, common clubmoss herb and veratrum, is crushed into 200 meshes of powder, sieved, uniformly mixed and prepared into water-honeyed pills.
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