CN114929747A - 多发性骨髓瘤的靶向bcma的car-t细胞疗法 - Google Patents

多发性骨髓瘤的靶向bcma的car-t细胞疗法 Download PDF

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CN114929747A
CN114929747A CN202080091870.8A CN202080091870A CN114929747A CN 114929747 A CN114929747 A CN 114929747A CN 202080091870 A CN202080091870 A CN 202080091870A CN 114929747 A CN114929747 A CN 114929747A
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car
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尤巴尼 E·祖代尔
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Janssen Biotech Inc
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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CN202080091870.8A 2019-11-05 2020-11-04 多发性骨髓瘤的靶向bcma的car-t细胞疗法 Pending CN114929747A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962931065P 2019-11-05 2019-11-05
US62/931065 2019-11-05
US201962943627P 2019-12-04 2019-12-04
US62/943627 2019-12-04
PCT/US2020/058788 WO2021091945A1 (en) 2019-11-05 2020-11-04 Bcma-targeted car-t cell therapy of multiple myeloma

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CN114929747A true CN114929747A (zh) 2022-08-19

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US (1) US12522645B2 (https=)
EP (1) EP4055049A1 (https=)
JP (1) JP2023500338A (https=)
KR (1) KR20220100612A (https=)
CN (1) CN114929747A (https=)
AU (1) AU2020378263A1 (https=)
BR (1) BR112022008633A2 (https=)
CA (1) CA3159808A1 (https=)
IL (1) IL292701A (https=)
JO (1) JOP20220099A1 (https=)
MX (1) MX2022005443A (https=)
PH (1) PH12022551032A1 (https=)
WO (1) WO2021091945A1 (https=)

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US20240156962A1 (en) * 2022-11-02 2024-05-16 Legend Biotech Usa Inc. Bcma-targeted car-t cell therapy of multiple myeloma
CN117186229B (zh) * 2022-12-06 2024-03-29 成都赛恩吉诺生物科技有限公司 具有长cdr3序列的抗人bcma纳米抗体及car-t和应用
CA3205511A1 (en) * 2023-04-19 2025-03-17 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2026072671A1 (en) 2024-09-24 2026-04-02 City Of Hope Methods comprising oncolytic viruses expressing bcmat and bcma-targeted therapies

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IL292701A (en) 2022-07-01
US20210128618A1 (en) 2021-05-06
PH12022551032A1 (en) 2023-04-24
KR20220100612A (ko) 2022-07-15
WO2021091945A1 (en) 2021-05-14
BR112022008633A2 (pt) 2022-07-19
CA3159808A1 (en) 2021-05-14
EP4055049A1 (en) 2022-09-14
AU2020378263A1 (en) 2022-06-23
JOP20220099A1 (ar) 2023-01-30
US12522645B2 (en) 2026-01-13
MX2022005443A (es) 2022-08-10

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