CN114901808A - 生产car-t细胞的方法 - Google Patents

生产car-t细胞的方法 Download PDF

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CN114901808A
CN114901808A CN202080090599.6A CN202080090599A CN114901808A CN 114901808 A CN114901808 A CN 114901808A CN 202080090599 A CN202080090599 A CN 202080090599A CN 114901808 A CN114901808 A CN 114901808A
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cells
cell
gene
gly
ala
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Chinese (zh)
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J.卡森
D.卡莱齐迪斯
S.谭
于慧
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CRISPR Therapeutics AG
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CRISPR Therapeutics AG
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CN202080090599.6A 2019-11-13 2020-11-13 生产car-t细胞的方法 Pending CN114901808A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962934999P 2019-11-13 2019-11-13
US62/934,999 2019-11-13
PCT/IB2020/060722 WO2021095012A1 (en) 2019-11-13 2020-11-13 Methods of manufacturing car-t cells

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CN114901808A true CN114901808A (zh) 2022-08-12

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US (1) US20210139935A1 (https=)
EP (1) EP4058559A1 (https=)
JP (1) JP2023501617A (https=)
KR (1) KR20220097985A (https=)
CN (1) CN114901808A (https=)
AR (1) AR120470A1 (https=)
AU (1) AU2020382017A1 (https=)
BR (1) BR112022009137A2 (https=)
CA (1) CA3158118A1 (https=)
CO (1) CO2022006800A2 (https=)
IL (1) IL292351A (https=)
MX (1) MX2022005817A (https=)
TW (1) TW202132560A (https=)
WO (1) WO2021095012A1 (https=)

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EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
AU2021286655A1 (en) 2020-06-12 2023-01-05 Nkarta, Inc. Genetically modified natural killer cells for CD70-directed cancer immunotherapy
KR20230118887A (ko) 2020-12-03 2023-08-14 센츄리 쎄라퓨틱스 인코포레이티드 유전자 조작 세포 및 이의 용도
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
TW202328444A (zh) * 2021-07-26 2023-07-16 瑞士商Ｃｒｉｓｐｒ治療公司 用於製造基因工程化ｃａｒ－ｔ細胞之方法
CN116023496B (zh) * 2021-10-27 2026-02-27 菲鹏弘济生物(深圳)有限公司 一种制备通用型car-t细胞的方法及其应用
AU2023314130A1 (en) * 2022-07-25 2025-02-06 Memorial Hospital For Cancer And Allied Diseases Manufacturing processes for adoptive cell therapies
AU2023373900A1 (en) * 2022-11-02 2025-05-15 Medisix Therapeutics, Inc. Methods and systems for production of engineered t-cells
US12473529B2 (en) 2023-07-18 2025-11-18 Nanotein Technologies, Inc. Reagents, reagent kits, and culture media for activating and expanding immune cells and uses thereof

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CN107206024A (zh) * 2014-10-31 2017-09-26 宾夕法尼亚大学董事会 改变cart细胞中的基因表达及其用途
CN109790517A (zh) * 2016-04-15 2019-05-21 纪念斯隆-凯特林癌症中心 转基因t细胞和嵌合抗原受体t细胞组合物和相关方法
WO2019097305A2 (en) * 2017-05-12 2019-05-23 Crispr Therapeutics Ag Materials and methods for engineering cells and uses thereof in immuno-oncology
WO2019152742A1 (en) * 2018-02-01 2019-08-08 Pfizer Inc. Chimeric antigen receptors targeting cd70

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