CN114886470A - Automatic throat swab nucleic acid sampling device and nucleic acid sampling method - Google Patents
Automatic throat swab nucleic acid sampling device and nucleic acid sampling method Download PDFInfo
- Publication number
- CN114886470A CN114886470A CN202210444255.1A CN202210444255A CN114886470A CN 114886470 A CN114886470 A CN 114886470A CN 202210444255 A CN202210444255 A CN 202210444255A CN 114886470 A CN114886470 A CN 114886470A
- Authority
- CN
- China
- Prior art keywords
- cotton swab
- nucleic acid
- shell
- reagent tube
- swab
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005070 sampling Methods 0.000 title claims abstract description 115
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 84
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 84
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 84
- 238000000034 method Methods 0.000 title claims abstract description 18
- 229920000742 Cotton Polymers 0.000 claims abstract description 134
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 99
- 230000007246 mechanism Effects 0.000 claims abstract description 90
- 238000007789 sealing Methods 0.000 claims abstract description 38
- 238000005192 partition Methods 0.000 claims description 20
- 230000036541 health Effects 0.000 claims description 9
- 230000009471 action Effects 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 6
- 230000007306 turnover Effects 0.000 claims description 5
- 210000000078 claw Anatomy 0.000 claims description 3
- 230000005484 gravity Effects 0.000 claims description 3
- 239000002906 medical waste Substances 0.000 claims description 3
- 238000012795 verification Methods 0.000 claims description 2
- 238000010008 shearing Methods 0.000 claims 1
- 230000006872 improvement Effects 0.000 description 8
- 241000700605 Viruses Species 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J11/00—Manipulators not otherwise provided for
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K17/00—Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations
- G06K17/0022—Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations arrangements or provisions for transferring data to distant stations, e.g. from a sensing device
-
- G—PHYSICS
- G07—CHECKING-DEVICES
- G07F—COIN-FREED OR LIKE APPARATUS
- G07F17/00—Coin-freed apparatus for hiring articles; Coin-freed facilities or services
- G07F17/04—Coin-freed apparatus for hiring articles; Coin-freed facilities or services for anthropometrical measurements, such as weight, height, strength
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Robotics (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses an automatic throat swab nucleic acid sampling device and a nucleic acid sampling method, and the automatic throat swab nucleic acid sampling device comprises a shell, an identity input system, a cotton swab supply mechanism, a nucleic acid sampling mechanism, a reagent tube arrangement mechanism and a controller, wherein the shell is provided with a first cavity and a second cavity; the identity input system comprises a magnetic card reader and a sticker printer; the cotton swab feeding mechanism is connected into the shell, a cotton swab throwing opening is formed in the shell at the top of the cotton swab feeding mechanism, and a sealing door B is arranged at the cotton swab throwing opening; the nucleic acid sampling mechanism is positioned at the bottom of the cotton swab supply mechanism, grabs the cotton swab from the cotton swab supply mechanism and extends out of the sampling port for rotary sampling; the reagent tube arrangement mechanism is arranged on the side part of the nucleic acid sampling mechanism, and a reagent tube feeding opening is formed in the shell at the top of the cotton swab supply mechanism. According to the invention, nucleic acid sampling is completed in sequence by a mechanized mechanism in a self-service sampling mode, so that the working pressure of medical staff is relieved, and the risk coefficient of the medical staff is reduced.
Description
Technical Field
The invention relates to the technical field of medical detection, in particular to an automatic throat swab nucleic acid sampling device and a nucleic acid sampling method.
Background
Based on the fact that the current global new crown pneumonia epidemic situation virus has strong transmission capability, wide transmission chain and high hiding performance and is difficult to distinguish, nucleic acid detection becomes a unique and accurate mode for detecting virus carriers, along with the diffusion of the virus transmission chain, the whole member nucleic acid detection becomes one of important means for blocking and finding out the infection source, in order to further block the infection of the virus and ensure the safety of lives and properties of people, the whole member nucleic acid collection work is developed in a large range nationwide at present, the work volume is large, the danger is high, and great work pressure is brought to medical workers, the main mode of the current nucleic acid collection is manual single collection, the cotton swabs are sequentially carried out to the personnel by mainly depending on the medical workers wearing protective clothing, the complicated step flow needs to be repeated hundreds of thousands of times, the work efficiency is low, the work environment is boring, and the work in the long-time isolation clothing brings serious physical quality tests to the medical workers, the risk of virus infection of medical personnel is greatly increased by using a manual face-to-face collection mode. At present, no automatic nucleic acid collection equipment with applicability is available on the market to help medical staff to collect nucleic acid.
Disclosure of Invention
The invention aims to provide an automatic throat swab nucleic acid sampling device and a nucleic acid sampling method, which mainly complete nucleic acid sampling in sequence by a mechanical mechanism in a self-service sampling mode, relieve the working pressure of medical personnel and reduce the risk coefficient of the medical personnel so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
an automatic throat swab nucleic acid sampling device comprises a shell, an identity input system, a cotton swab supply mechanism, a nucleic acid sampling mechanism, a reagent tube arrangement mechanism and a controller; the device comprises a shell, a controller and a paper cup box, wherein at least one sealing door A is arranged on two sides of the shell, the bottom of the shell is provided with a sample storage box for storing collected samples, the outer wall of the front side of the shell is connected with the paper cup box, a conical sampling port and a sample putting port, and the controller is arranged in the shell; the identity input system comprises a magnetic card reader and a sticker printer; the magnetic card reader is of an integrated structure and is connected to the outer wall of the front face of the shell, a scanning screen is arranged on the magnetic card reader, the printer is connected to the inner wall of the shell, and a sticker outlet is formed in the front face of the shell; the cotton swab feeding mechanism is connected into the shell, a cotton swab throwing opening is formed in the shell at the top of the cotton swab feeding mechanism, and a sealing door B is arranged at the cotton swab throwing opening; the nucleic acid sampling mechanism is positioned at the bottom of the cotton swab supply mechanism, grabs the cotton swab from the cotton swab supply mechanism and extends out of the sampling port for rotary sampling; the reagent tube arranging mechanism is arranged on the side portion of the nucleic acid sampling mechanism, a reagent tube feeding opening is formed in a shell at the top of the cotton swab supplying mechanism, a sealing door C is arranged at the reagent tube feeding opening, one end of the reagent tube arranging mechanism leads to a conveying opening in the front face of the shell, and a sealing door D is connected to the conveying opening.
The invention has the further improvement scheme that disposable paper cups in the paper cup box can be folded and orderly stacked in the paper cup box, the paper cups can be sleeved on the outer wall of the sampling opening after being unfolded, and the sampling opening is provided with a first proximity switch; the sealing doors A are two symmetrically arranged sliding doors, and handles are connected to the sealing doors A; the sealing door B and the sealing door C are sliding doors; the sample storage box is of a drawing structure.
The invention has the further improvement scheme that the cotton swab feeding mechanism comprises a cotton swab feeding box, a first cylinder and a pneumatic suction rod; a horizontally arranged partition plate is arranged above the inner part of the shell, the upper part of the cotton swab putting box is V-shaped, the lower part of the cotton swab putting box is rectangular, the top of the cotton swab putting box is opened and communicated with the cotton swab putting opening, and the bottom of the cotton swab putting box is connected to the partition plate and provided with a swab outlet hole; the first air cylinder is connected to the partition plate, the power output end of the first air cylinder is connected with the support plate, the partition plate is connected with a slide rail parallel to the first air cylinder, the bottom of the support plate is connected with a slide block, and the slide block support plate is connected to the slide rail in a sliding mode through the slide block; the pneumatic suction rod is connected to the other end of the supporting plate, the soft suction nozzle is connected to the end portion of the pneumatic suction rod, and the first air cylinder drives the pneumatic suction rod to be close to the label outlet hole.
The invention has the further improvement that the cotton swab feeding mechanism also comprises a stop lever and a turnover box; pneumatic suction rod below is equipped with the logical groove that the overall dimension is greater than the cotton swab size, and the pin is connected in keeping away from logical groove of a hole one end of signing, the upset box is connected in the baffle bottom, and upset box open-top and intercommunication notch, the upset box keep away from in a hole one side open and be equipped with the breach to make the cotton swab afterbody expose in the outside of upset box.
The invention has the further improvement scheme that the nucleic acid sampling mechanism comprises a motor, a screw rod, a nut block, a second cylinder, a steering engine and a manipulator a; the screw rod is rotationally connected to the inner wall of the shell and parallel to the central axis of the sampling port, the motor is connected to the outer wall of the back of the shell and is connected to the screw rod in a driving mode; the interior of the shell is at least connected with a guide rod parallel to the lead screw, the nut block is in threaded fit with the lead screw, and the nut block is connected to the guide rod in a sliding manner through a guide hole; the second cylinder is vertically connected to two sides of the nut block, the top end of the second cylinder is connected with a lifting plate, the steering engine is connected to the top end of the lifting plate, a power output end of the steering engine is connected with an eccentric disc, a manipulator a is horizontally connected to the eccentric disc, and an infrared distance measuring device is connected to the manipulator a.
In a further improvement of the invention, the nucleic acid sampling mechanism further comprises a third air cylinder and pneumatic scissors; the positive inner wall of casing is connected with the support, and third cylinder transverse connection is on the support, and pneumatic scissors is connected in the power take off end of third cylinder, and takes the clamping jaw on the pneumatic scissors in order to snatch the cotton swab head after cutting off, and pneumatic scissors of third cylinder drive removes to reagent pipe arrangement mechanism department.
The invention has the further improvement that the reagent tube arrangement mechanism comprises a reagent tube putting box, a baffle ring and a cone hopper; the reagent tube throwing box is connected to the top of the shell, the upper part of the reagent throwing box is V-shaped, the bottom of the reagent throwing box is connected with a ramp, and the top of the reagent tube throwing box is opened and communicated with a reagent tube throwing port; the three baffle rings are connected in series in parallel and are connected in series through the rotating shaft, the baffle rings are rotatably connected to the intersection of the ramp and the reagent tube feeding port, the driving device drives the rotating shaft to rotate, and the baffle rings are provided with arc-shaped bayonets; one side in the ramp is connected with the raised bump, the conical hopper is vertically connected to the bottom of the ramp, and the conical hopper is connected with a second proximity switch.
According to a further improvement scheme of the invention, the reagent tube arrangement mechanism further comprises a conveyor belt, a fourth cylinder, a fifth cylinder, a manipulator b and a manipulator c; the conveying belt is connected to the shell at the bottom of the conical hopper, a plurality of positioning pipes are connected to the conveying belt, and one end of the conveying belt extends to the conveying opening; the fourth cylinder is vertically connected to the bottom of the partition plate above the conveyor belt, and the manipulator b is connected to the power output end of the fourth cylinder; the fifth cylinder is connected to the shell on the side of the conveyor belt, and the manipulator c is connected to the power output end of the fifth cylinder.
The invention has the further improvement scheme that the sealing door D is a hidden automatic door, a blanking table is connected on the shell outside the conveying port, and a plurality of ultraviolet lamps are connected on the partition board in the shell.
A nucleic acid sampling method using the automatic throat swab nucleic acid sampling device comprises the following steps:
s1, the identity information of the detected person can be input into the integrated magnetic card reader, the scanning screen on the magnetic card reader is used for scanning the health code data of the person, the health code data and the identity information are unified into authentication data on the premise that a chip arranged in the magnetic card reader is based on big data of the person information, the read authentication data can be printed into a sticker of a two-dimensional code data bar code through a printer, and the sticker flows out from the outlet of the sticker;
s2, after the magnetic card reader records the identity information and the health code data, the controller receives the signal and sends a working instruction to the label supply mechanism; cotton swabs in the cotton swab putting box are sequentially arranged, the cotton swab head at the bottommost part is right opposite to the cotton swab outlet, and the first air cylinder drives the soft suction nozzle of the pneumatic suction rod to move towards the cotton swab outlet and suck the cotton swabs; then the first cylinder drives the cotton swab to move backwards and slowly, when the cotton swab is completely separated from the cotton swab putting box, the soft suction nozzle loses suction, the cotton swab can fall freely under the action of gravity, and due to the action of the stop lever, the cotton swab can turn over after falling freely, so that the cotton swab head is turned to the direction of the sampling port and falls into the turning box, and the cotton swab rod is partially exposed out of the turning box;
s3, the collected personnel take the disposable paper cup from the bottom of the paper cup box and unfold the disposable paper cup to be sleeved on the outer wall of the conical sampling opening, and the personnel hold the paper cup in the mouth to avoid cross contact; after the former detected person finishes the detection, the paper cup needs to be taken down and thrown into a special garbage can for medical wastes;
s4, after the collected person is ready, the first proximity switch feeds back a signal to the controller, and the controller sends a working instruction to the nucleic acid sampling mechanism; the motor and the second cylinder act in a matched mode, the mechanical arm a grabs the cotton swab, the motor drives the nut block to move transversely to the sampling opening, the infrared distance measuring device detects the actual distance between the head of the cotton swab and the throat of a human body, and the mechanical arm a reaches a proper position and stops after calculation inside the controller; the steering engine drives the manipulator a to rotate to sample nucleic acid; after sampling is finished, the manipulator a retreats; the third cylinder drives the pneumatic scissors to extend out to cut the cotton swab rod, and the pneumatic scissors grab and rotate the cotton swab head so that the cotton swab head is kept in a vertical state.
S5, arranging the reagent tubes in the reagent tube feeding box in order, and clamping the reagent tube at the bottommost part at the bayonet of the baffle ring; after the second proximity switch on the cone bucket detects the positioning tube, the driving device drives the rotating shaft to rotate, the reagent tube falls onto the ramp and touches the bump, and the reagent tube falls into the positioning tube along the cone bucket; the reagent tube is conveyed to the end of the conveying port by the conveying belt, after the reagent tube is detected by the mechanical arm c, the tube body of the reagent tube is grasped, meanwhile, the cover of the reagent tube is grabbed by the mechanical arm b and is unscrewed and lifted, the swab head is conveyed to the upper part of the tube body by the pneumatic scissors and is loosened, the swab head falls into the reagent tube, the pneumatic scissors return, and the cover is screwed by the mechanical arm b; the conveyor belt continues to move forwards, the sealing door D at the conveying opening is opened at the moment, the reagent tube is sent out along the conveying opening and falls on the blanking table, and the sealing door D is closed;
s6, the collected person takes up the reagent tube, information on the sticker is verified, the sticker is pasted on the outer wall of the reagent tube after the information is verified to be correct, and the reagent tube is put into the sample storage box from the sample putting port.
The invention has the beneficial effects that:
firstly, the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method of the invention complete nucleic acid sampling in sequence by a mechanical mechanism mainly in a self-service sampling mode, relieve the working pressure of medical staff and reduce the risk coefficient of the medical staff.
Secondly, the automatic throat swab nucleic acid sampling device and the automatic throat swab nucleic acid sampling method adopt the disposable and foldable paper cup to be sleeved on the outer wall of the sampling opening, thereby preventing cross infection and being more sanitary and safer.
Thirdly, the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method of the invention take out the cotton swab put in the box by adopting a software suction nozzle negative pressure suction mode, thereby ensuring that the cotton swab head is not damaged.
Fourthly, according to the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method, the cotton swab is turned over and falls into the turning box in the falling process, and the cotton swab rod is exposed outside the turning box, so that the nucleic acid sampling mechanism is convenient to take and use.
Fifth, the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method of the invention have the advantages that the mechanical arm a is arranged on the eccentric disc, and the steering engine drives the eccentric disc to rotate, so that the coverage range of the swab head is increased, and the sampling result is more accurate.
Sixthly, according to the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method, the clamping claws are arranged on the pneumatic scissors, so that the cut cotton swab heads can be grabbed and sent to the reagent tube.
Seventhly, according to the automatic throat swab nucleic acid sampling device and the nucleic acid sampling method, the blocking ring with the bayonet is arranged between the reagent tube feeding box and the ramp, so that the falling of the reagent tube can be controlled in order.
Eighth, according to the automated pharyngeal swab nucleic acid sampling device and the nucleic acid sampling method of the present invention, the ramp is connected with a bump to ensure that the horizontal reagent tube can enter the conical funnel in a standing manner.
Ninth, according to the automated pharyngeal swab nucleic acid sampling device and the nucleic acid sampling method of the present invention, the partition board inside the housing is connected with a plurality of ultraviolet lamps, which can meet the requirement of disinfection inside the device.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
Fig. 2 is a schematic view of the overall structure of the present invention.
Fig. 3 is a schematic view of the overall structure of the present invention.
Fig. 4 is a schematic view of the overall structure of the present invention.
FIG. 5 is a partial schematic structural view of the reagent vessel aligning mechanism of the present invention.
Fig. 6 is a partial structural view of the swab feeding mechanism of the present invention.
FIG. 7 is a schematic structural view of a cotton swab feeding mechanism and a nucleic acid sampling mechanism according to the present invention.
FIG. 8 is a schematic structural view of a nucleic acid sampling mechanism of the present invention.
Fig. 9 is a partial structural view of the swab feeding mechanism of the present invention.
In the figure: 1-shell, 101-sealing door A, 102-sampling port, 103-sample putting port, 104-sticker outlet, 105-cotton swab putting port, 106-sealing door B, 107-reagent tube putting port, 108-sealing door C, 109-conveying port, 110-sealing door D, 111-clapboard, 112-through groove, 113-support, 114-blanking table, 115-sample storage box, 2-identity recording mechanism, 201-magnetic card reader, 202-scanning screen, 203-printer, 3-cotton swab supply mechanism, 301-cotton swab putting box, 302-first cylinder, 303-pneumatic suction rod, 304-output hole, 305-support plate, 306-slide rail, 307-soft suction nozzle, 308-stop rod, 309-turnover box, 4-nucleic acid sampling mechanism, 401-motor, 402-lead screw, 403-nut block, 404-second cylinder, 405-steering engine, 406-manipulator a, 407-guide rod, 408-lifting plate, 409-eccentric disc, 410-third cylinder, 411-pneumatic scissors, 5-reagent tube arranging mechanism, 501-reagent tube putting box, 502-baffle ring, 503-cone bucket, 504-ramp, 505-bayonet, 506-lug, 507-conveyor belt, 508-fourth cylinder, 509-fifth cylinder, 510-manipulator b, 511-manipulator c, 512-positioning tube, 6-paper cup box, 7-ultraviolet lamp, 8-cotton swab, 801-cotton swab head, 802-cotton swab rod, 9-reagent tube, 901-tube, 902-cap.
Detailed Description
The invention is further elucidated with reference to the drawings and the embodiments.
Example 1: as shown in fig. 1 to 9, an automated pharyngeal swab nucleic acid sampling device comprises a shell 1, an identity recording system 2, a cotton swab supply mechanism 3, a nucleic acid sampling mechanism 4, a reagent tube arrangement mechanism 5 and a controller; the device comprises a shell 1, a paper cup box 6, a conical sampling port 102 and a sample putting port 103, wherein at least one sealing door A101 is arranged on two sides of the shell 1, a sample storage box 115 for storing collected samples is arranged at the bottom of the shell 1, the outer wall of the front side of the shell 1 is connected with the paper cup box 6, the conical sampling port 102 and the sample putting port 103, and a controller is arranged in the shell 1; the identity input system 2 comprises a magnetic card reader 201 and a sticker printer 203; the magnetic card reader 201 is of an integrated structure and is connected to the outer wall of the front side of the shell 1, the magnetic card reader 201 is provided with a scanning screen 202, the printer 203 is connected to the inner wall of the shell 1, and the front side of the shell 1 is provided with a sticker outlet 104; the cotton swab feeding mechanism 3 is connected into the shell 1, a cotton swab putting opening 105 is formed in the shell 1 at the top of the cotton swab feeding mechanism 3, and a sealing door B106 is arranged at the cotton swab putting opening 105; the nucleic acid sampling mechanism 4 is positioned at the bottom of the cotton swab supply mechanism 3, and the nucleic acid sampling mechanism 4 grabs the cotton swab 8 from the cotton swab supply mechanism 3 and extends out of the sampling port 102 for rotary sampling; the reagent tube arraying mechanism 5 is arranged on the side part of the nucleic acid sampling mechanism 4, a reagent tube feeding port 107 is arranged on the shell 1 at the top of the cotton swab supplying mechanism 3, a sealing door C108 is arranged at the reagent tube feeding port 107, one end of the reagent tube arraying mechanism 5 leads to a conveying port 109 on the front surface of the shell 1, and the conveying port 109 is connected with a sealing door D110.
The disposable paper cups in the paper cup box 6 can be folded and orderly stacked in the paper cup box 6, the paper cups can be sleeved on the outer wall of the sampling port 102 after being unfolded, and a first proximity switch is arranged at the sampling port 102; the sealing doors A101 are sliding doors and are symmetrically arranged, and the handles are connected to the sealing doors A101; the sealing door B106 and the sealing door C108 are sliding doors; the sample storage cassette 115 has a drawer-type structure.
The cotton swab feeding mechanism 3 comprises a cotton swab putting box 301, a first air cylinder 302 and a pneumatic suction rod 303; a partition board 111 which is horizontally arranged is arranged above the inner part of the shell 1, the upper part of the cotton swab putting box 301 is V-shaped, the lower part of the cotton swab putting box 301 is rectangular, the top of the cotton swab putting box 301 is opened and communicated with the cotton swab putting opening 105, and the bottom of the cotton swab putting box 301 is connected to the partition board 111 and is provided with a swab outlet hole 304; the first air cylinder 302 is connected to the partition plate 111, the power output end of the first air cylinder 302 is connected with a support plate 305, the partition plate 111 is connected with a slide rail 306 parallel to the first air cylinder 302, the bottom of the support plate 305 is connected with a slide block, and the slide block support plate 305 is connected to the slide rail 306 in a sliding manner through the slide block; the pneumatic suction rod 303 is connected to the other end of the support plate 305, the soft suction nozzle 307 is connected to the end of the pneumatic suction rod 303, and the first air cylinder 302 drives the pneumatic suction rod 303 to approach the label outlet 304.
The cotton swab feeding mechanism 3 further comprises a stop lever 308 and an overturning box 309; the pneumatic suction rod 303 is provided with a through groove 112 with the inner size larger than the size of the cotton swab 8, the stop rod 308 is connected in the through groove 112 far away from one end of the swab outlet 304, the turning box 309 is connected to the bottom of the partition board 111, the top of the turning box 309 is opened and is connected with the through groove 112, one side of the turning box 309 far away from the swab outlet 304 is opened and is provided with a notch, so that the tail of the cotton swab 8 is exposed out of the turning box 309.
The nucleic acid sampling mechanism 4 comprises a motor 401, a lead screw 402, a nut block 403, a second cylinder 404, a steering engine 405 and a manipulator a 406; the screw 402 is rotatably connected to the inner wall of the shell 1, the screw 402 is parallel to the central axis of the sampling port 102, the motor 401 is connected to the outer wall of the back of the shell 1, and the motor 401 is connected to the screw 402 in a driving manner; at least one guide rod 407 parallel to the screw 402 is connected to the inside of the housing 1, the nut block 403 is in threaded fit with the screw 402, and the nut block 403 is slidably connected to the guide rod 407 through a guide hole; the second cylinder 404 is vertically connected to two sides of the nut block 403, the top end of the second cylinder 404 is connected with a lifting plate 408, the steering engine 405 is connected to the top end of the lifting plate 408, the power output end of the steering engine 405 is connected with an eccentric disc 409, the manipulator a406 is horizontally connected to the eccentric disc 409, and the manipulator a406 is connected with an infrared distance measuring device.
Wherein the nucleic acid sampling mechanism 4 further comprises a third cylinder 410 and a pneumatic scissors 411; the inner wall of the front surface of the housing 1 is connected with a support 113, a third air cylinder 410 is transversely connected to the support 113, a pneumatic scissors 411 is connected to the power output end of the third air cylinder 410, the pneumatic scissors 411 are provided with clamping claws to grab the cut cotton swab head 801, and the third air cylinder 410 drives the pneumatic scissors 411 to move to the reagent tube arranging mechanism 5.
The reagent tube arrangement mechanism 5 comprises a reagent tube feeding opening 501, a baffle ring 502 and a conical hopper 503; the reagent tube feeding port 501 is connected to the top of the shell 1, the upper part of the reagent feeding box is V-shaped, the bottom of the reagent feeding box is connected with a ramp 504, and the top of the reagent tube feeding port 501 is opened and communicated with the reagent tube feeding port 107; the baffle rings 502 are three in parallel and series connection, are connected in series through rotating shafts, are rotatably connected to the intersection of the ramp 504 and the reagent tube feeding port 501, the driving device drives the rotating shafts to rotate, and an arc-shaped bayonet 505 is arranged on the baffle ring 502; a raised bump 506 is connected to one side in the ramp 504, the conical hopper 503 is vertically connected to the bottom of the ramp 504, and a second proximity switch is connected to the conical hopper 503.
The reagent tube arrangement mechanism 5 further comprises a conveyor belt 507, a fourth cylinder 508, a fifth cylinder 509, a manipulator b510 and a manipulator c 511; the conveyor belt 507 is connected to the shell 1 at the bottom of the conical hopper 503, the conveyor belt 507 is connected with a plurality of positioning pipes 512, and one end of the conveyor belt 507 extends to the conveying port 109; the fourth cylinder 508 is vertically connected to the bottom of the partition board 111 above the conveyor 507, and the manipulator b510 is connected to the power output end of the fourth cylinder 508; the fifth cylinder 509 is connected to the casing 1 on the side of the conveyor 507, and the robot c511 is connected to a power output end of the fifth cylinder 509.
The sealing door D110 is a hidden automatic door, the casing 1 outside the delivery port 109 is connected to a blanking table 114, and a plurality of ultraviolet lamps 7 are connected to a partition plate 111 inside the casing 1.
Example 2: the embodiment discloses a nucleic acid sampling method, which uses an automatic throat swab nucleic acid sampling device in the embodiment, and comprises the following steps:
s1, the identity information of the detected person can be input into the integrated magnetic card reader 201, the scanning screen 202 on the magnetic card reader 201 is used for scanning the health code data of the person, the health code data and the identity information are unified into authentication data on the premise that a chip arranged in the magnetic card reader 201 is based on big data of the person information, the read authentication data can be printed into a two-dimensional code data bar-code sticker through the printer 203, and the two-dimensional code data bar-code sticker flows out from the sticker outlet 104;
s2, after the magnetic card reader 201 inputs the identity information and the health code data, the controller receives the signal and sends a working instruction to the label supply mechanism; the cotton swabs 8 in the cotton swab putting box 301 are arranged in sequence, the cotton swab head 801 at the bottommost part faces the swab outlet hole 304, and the first air cylinder 302 drives the soft suction nozzle 307 of the pneumatic suction rod 303 to move towards the swab outlet hole 304 and suck the cotton swabs 8; then the first cylinder 302 drives the cotton swab 8 to move backwards and slowly, when the cotton swab 8 is completely separated from the cotton swab putting box 301, the soft suction nozzle 307 loses suction force, the cotton swab 8 falls freely under the action of gravity, and due to the action of the stop rod 308, the cotton swab 8 turns over after falling freely, the cotton swab head 801 is turned to the sampling port 102 and falls into the turning box 309, and the cotton swab rod 802 is partially exposed out of the turning box 309;
s3, the collected personnel takes out the disposable paper cup from the bottom of the paper cup box 6 and unfold the disposable paper cup to be sleeved on the outer wall of the conical sampling opening 102, and the personnel can avoid cross contact when holding the paper cup in the mouth; after the former detected person finishes the detection, the paper cup needs to be taken down and thrown into a special garbage can for medical wastes;
s4, after the collected person is ready, the first proximity switch feeds back a signal to the controller, and the controller sends a working instruction to the nucleic acid sampling mechanism 4; the motor 401 and the second cylinder 404 act in a matched mode, the mechanical arm a406 grabs the cotton swab 8, the motor 401 drives the nut block 403 to move transversely to the sampling port 102, the infrared distance measuring device detects the actual distance between the cotton swab head 801 and the throat of a human body, and after calculation in the controller, the mechanical arm a406 reaches a proper position and stops; the steering engine 405 drives the manipulator a406 to rotate to sample nucleic acid; after sampling is completed, the manipulator a406 retreats; the third cylinder 410 drives the pneumatic scissors 411 to extend out to cut the cotton swab shaft 802, and the pneumatic scissors 411 grab the cotton swab head 801 and rotate, so that the cotton swab head 801 is kept in a vertical state.
S5, arranging the reagent tubes 9 in the reagent tube feeding port 501 in order, and clamping the reagent tube 9 at the bottommost part at the bayonet 505 of the baffle ring 502; after the second proximity switch on the cone bucket 503 detects the positioning tube 512, the driving device drives the rotating shaft to rotate, the reagent tube 9 falls onto the ramp 504 and touches the bump 506, and the reagent tube 9 falls into the positioning tube 512 along the cone bucket 503; the reagent tube 9 is conveyed to the end of the conveying opening 109 by the conveying belt 507, after the manipulator c511 detects the reagent tube 9, the manipulator c grasps the tube body 901 of the reagent tube 9, meanwhile, the manipulator b510 grasps the cover 902 of the reagent tube 9 and screws down and lifts up, the swab head 801 is conveyed to the position above the tube body 901 by the pneumatic scissors 411 and is loosened, the swab head 801 falls into the reagent tube 9, the pneumatic scissors 411 retracts, and the manipulator b510 screws up the cover 902; the conveyor 507 continues to move forward, and at this time, the sealing door D110 at the conveyor opening 109 is opened, the reagent tube 9 is sent out along the conveyor opening 109 and falls on the blanking table 114, and the sealing door D110 is closed;
s6, the person to be collected picks up the reagent tube 9, verifies the information on the sticker, attaches the sticker to the outer wall of the reagent tube 9 after verification, and drops the reagent tube 9 into the sample storage box 115 from the sample drop port 103.
The above embodiments are merely illustrative of the technical concepts and features of the present invention, and the purpose of the embodiments is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and not to limit the protection scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.
Claims (10)
1. An automated pharyngeal swab nucleic acid sampling device, comprising: comprises a shell (1), an identity recording system (2), a cotton swab supply mechanism (3), a nucleic acid sampling mechanism (4), a reagent tube arrangement mechanism (5) and a controller;
the device is characterized in that at least one sealing door A (101) is arranged on each of two sides of the shell (1), a sample storage box (115) for storing collected samples is arranged at the bottom of the shell (1), a paper cup box (6), a conical sampling port (102) and a sample putting port (103) are connected to the outer wall of the front of the shell (1), and the controller is arranged in the shell (1);
the identity entry system (2) comprises a magnetic card reader (201) and a sticker printer (203); the magnetic card reader (201) is of an integrated structure and is connected to the outer wall of the front side of the shell (1), a scanning screen (202) is arranged on the magnetic card reader (201), the printer (203) is connected to the inner wall of the shell (1), and a sticker outlet (104) is arranged on the front side of the shell (1);
the cotton swab feeding mechanism (3) is connected into the shell (1), a cotton swab putting opening (105) is formed in the shell (1) at the top of the cotton swab feeding mechanism (3), and a sealing door B (106) is arranged at the cotton swab putting opening (105);
the nucleic acid sampling mechanism (4) is positioned at the bottom of the cotton swab supply mechanism (3), and the nucleic acid sampling mechanism (4) grabs the cotton swab (8) from the cotton swab supply mechanism (3) and extends out of the sampling port (102) for rotary sampling;
the reagent tube arraying mechanism (5) is arranged on the side of the nucleic acid sampling mechanism (4), a reagent tube putting-in opening (107) is formed in the shell (1) at the top of the cotton swab supplying mechanism (3), a sealing door C (108) is arranged at the reagent tube putting-in opening (107), one end of the reagent tube arraying mechanism (5) leads to a conveying opening (109) in the front of the shell (1), and a sealing door D (110) is connected to the conveying opening (109).
2. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 1, wherein: disposable paper cups in the paper cup box (6) can be folded and stacked in the paper cup box (6) in order, the paper cups can be sleeved on the outer wall of the sampling port (102) after being unfolded, and a first proximity switch is arranged at the sampling port (102); the sealing door A (101) is a sliding door and is symmetrically arranged, and the handle is connected to the sealing door A (101); the sealing door B (106) and the sealing door C (108) are sliding doors; the sample storage box (115) is of a drawing structure.
3. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 2, wherein: the cotton swab feeding mechanism (3) comprises a cotton swab feeding box (301), a first air cylinder (302) and a pneumatic suction rod (303); a partition plate (111) is horizontally arranged above the inner part of the shell (1), the upper part of the cotton swab putting box (301) is V-shaped, the lower part of the cotton swab putting box is rectangular, the top of the cotton swab putting box (301) is opened and communicated with the cotton swab putting opening (105), and the bottom of the cotton swab putting box (301) is connected to the partition plate (111) and is provided with a swab outlet hole (304); the first air cylinder (302) is connected to the partition plate (111), the power output end of the first air cylinder (302) is connected with a support plate (305), the partition plate (111) is connected with a slide rail (306) parallel to the first air cylinder (302), the bottom of the support plate (305) is connected with a slide block, and the slide block support plate (305) is connected to the slide rail (306) in a sliding manner through the slide block; the pneumatic suction rod (303) is connected to the other end of the supporting plate (305), the soft suction nozzle (307) is connected to the end of the pneumatic suction rod (303), and the first air cylinder (302) drives the pneumatic suction rod (303) to be close to the swab outlet hole (304).
4. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 3, wherein: the cotton swab feeding mechanism (3) further comprises a stop lever (308) and a turning box (309); pneumatic pole (303) below is equipped with logical groove (112) that the overall dimension is greater than cotton swab (8) size, and pin (308) are connected in keeping away from logical groove (112) of a hole (304) one end of signing out, upset box (309) are connected in baffle (111) bottom, and upset box (309) open-top parallel connection leads to groove (112) mouth, and one side of keeping away from in a hole (304) of signing out is opened and is equipped with the breach in upset box (309) to make cotton swab (8) afterbody expose in the outside of upset box (309).
5. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 3 or claim 4, wherein: the nucleic acid sampling mechanism (4) comprises a motor (401), a lead screw (402), a nut block (403), a second cylinder (404), a steering engine (405) and a manipulator a (406); the screw rod (402) is rotatably connected to the inner wall of the shell (1), the screw rod (402) is parallel to the central axis of the sampling port (102), the motor (401) is connected to the outer wall of the back of the shell (1), and the motor (401) is connected to the screw rod (402) in a driving mode; at least one guide rod (407) parallel to the lead screw (402) is connected to the interior of the shell (1), the nut block (403) is in threaded fit with the lead screw (402), and the nut block (403) is connected to the guide rod (407) in a sliding mode through a guide hole; second cylinder (404) vertical connection is in the both sides of nut piece (403), and the top of second cylinder (404) is connected with lifter plate (408), and steering wheel (405) are connected in the top of lifter plate (408), and the power take off end of steering wheel (405) is connected with eccentric disc (409), and manipulator a (406) horizontal connection is on eccentric disc (409), and is connected with infrared distance measuring device on manipulator a (406).
6. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 5, wherein: the nucleic acid sampling mechanism (4) further comprises a third air cylinder (410) and a pneumatic scissors (411); the inner wall of the front side of the shell (1) is connected with a support (113), a third air cylinder (410) is transversely connected onto the support (113), a pneumatic scissors (411) is connected onto the power output end of the third air cylinder (410), clamping claws are arranged on the pneumatic scissors (411) to grab the cut cotton swab head (801), and the third air cylinder (410) drives the pneumatic scissors (411) to move to the reagent tube arranging mechanism (5).
7. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 6, wherein: the reagent tube arrangement mechanism (5) comprises a reagent tube feeding opening (501), a baffle ring (502) and a conical hopper (503); the reagent tube feeding port (501) is connected to the top of the shell (1), the upper part of the reagent feeding box is V-shaped, the bottom of the reagent feeding box is connected with a ramp (504), and the top of the reagent tube feeding port (501) is opened and communicated with the reagent tube feeding port (107); the three baffle rings (502) are connected in series in parallel and in series through rotating shafts, and are rotatably connected to the intersection of the ramp (504) and the reagent tube feeding port (501), the driving device drives the rotating shafts to rotate, and an arc-shaped bayonet (505) is arranged on each baffle ring (502); a raised bump (506) is connected to one side in the ramp (504), the conical hopper (503) is vertically connected to the bottom of the ramp (504), and a second proximity switch is connected to the conical hopper (503).
8. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 7, wherein: the reagent tube arrangement mechanism (5) further comprises a conveyor belt (507), a fourth cylinder (508), a fifth cylinder (509), a manipulator b (510) and a manipulator c (511); the conveying belt (507) is connected to the shell (1) at the bottom of the conical hopper (503), the conveying belt (507) is connected with a plurality of positioning pipes (512), and one end of the conveying belt (507) extends to the conveying opening (109); the fourth cylinder (508) is vertically connected to the bottom of the partition plate (111) above the conveyor belt (507), and the manipulator b (510) is connected to the power output end of the fourth cylinder (508); the fifth cylinder (509) is connected to the shell (1) on the side of the conveyor belt (507), and the manipulator c (511) is connected to the power output end of the fifth cylinder (509).
9. An automated pharyngeal swab nucleic acid sampling apparatus as recited in claim 3, wherein: the sealing door D (110) is a hidden automatic door, a blanking table (114) is connected to the shell (1) on the outer side of the conveying opening (109), and a plurality of ultraviolet lamps (7) are connected to a partition plate (111) in the shell (1).
10. A method of nucleic acid sampling using an automated pharyngeal swab nucleic acid sampling device as claimed in any one of claims 1 to 9, comprising the steps of:
s1, identity information of a detected person can be input into the integrated magnetic card reader (201), a scanning screen (202) on the magnetic card reader (201) is used for scanning health code data of the person, the health code data and the identity information are unified into authentication data on the premise that a chip arranged in the magnetic card reader (201) is based on big data of the person information, the read authentication data can be printed into a two-dimensional code data bar code sticker through a printer (203), and the two-dimensional code data bar code sticker flows out from a sticker outlet (104);
s2, after the magnetic card reader (201) inputs the identity information and the health code data, the controller receives the signal and sends a working instruction to the label supply mechanism; cotton swabs (8) in the cotton swab throwing box (301) are sequentially arranged, the cotton swab head (801) at the bottommost part faces the swab outlet hole (304), and the first air cylinder (302) drives the soft suction nozzle (307) of the pneumatic suction rod (303) to move towards the swab outlet hole (304) and suck the cotton swabs (8); then the first cylinder (302) drives the cotton swab (8) to move backwards and slowly, when the cotton swab (8) is completely separated from the cotton swab putting box (301), the soft suction nozzle (307) loses suction, the cotton swab (8) can fall freely under the action of gravity, due to the action of the stop lever (308), the cotton swab (8) can turn over after falling freely, the direction that the cotton swab head (801) is turned to the sampling port (102) falls into the turnover box (309), and the cotton swab rod (802) is partially exposed out of the turnover box (309);
s3, the collected personnel take the disposable paper cup from the bottom of the paper cup box (6) and unfold the disposable paper cup to be sleeved on the outer wall of the tapered sampling port (102), and the personnel hold the paper cup in the mouth to avoid cross contact; after the former detected person finishes the detection, the paper cup needs to be taken down and thrown into a special garbage can for medical wastes;
s4, after the collected person is ready, the first proximity switch feeds back a signal to the controller, and the controller sends a working instruction to the nucleic acid sampling mechanism (4); the motor (401) and the second cylinder (404) act in a matched mode, the mechanical arm a (406) grabs the cotton swab (8), the motor (401) drives the nut block (403) to move transversely to the sampling port (102), the infrared distance measuring device detects the actual distance between the cotton swab head (801) and the throat of a human body, and after calculation in the controller, the mechanical arm a (406) reaches a proper position and stops; the steering engine (405) drives the manipulator a (406) to rotate to sample nucleic acid; after sampling is finished, the manipulator a (406) retreats; the third air cylinder (410) drives the pneumatic scissors (411) to extend out of the cotton swab shearing rod (802), and the pneumatic scissors (411) grab and rotate the cotton swab head (801) so that the cotton swab head (801) is kept in a vertical state;
s5, arranging the reagent tubes (9) in the reagent tube feeding port (501) in order, and clamping the reagent tube (9) at the bottommost part at the bayonet (505) of the baffle ring (502); after a second proximity switch on the cone bucket (503) detects the positioning tube (512), the driving device drives the rotating shaft to rotate, the reagent tube (9) falls onto the ramp (504) and touches the bump (506), and the reagent tube (9) falls into the positioning tube (512) along the cone bucket (503); the reagent tube (9) is conveyed to the end of the conveying opening (109) by a conveying belt (507), after the reagent tube (9) is detected by a manipulator c (511), a tube body (901) of the reagent tube (9) is grabbed, meanwhile, a cover (902) of the reagent tube (9) is grabbed by a manipulator b (510) and is unscrewed and lifted, a cotton swab head (801) is conveyed to the upper part of the tube body (901) by a pneumatic scissor (411) and is loosened, the cotton swab head (801) falls into the reagent tube (9), the pneumatic scissor (411) retracts, and the cover (902) is screwed by the manipulator b (510); the conveyor belt (507) continues to move forwards, at the moment, a sealing door D (110) at the position of the conveying opening (109) is opened, the reagent tube (9) is sent out along the conveying opening (109) and falls on a blanking table (114), and the sealing door D (110) is closed;
s6, the person to be collected picks up the reagent tube (9), verifies the information on the sticker, attaches the sticker to the outer wall of the reagent tube (9) after verification, and puts the reagent tube (9) into the sample storage box (115) from the sample putting port (103).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210444255.1A CN114886470A (en) | 2022-04-24 | 2022-04-24 | Automatic throat swab nucleic acid sampling device and nucleic acid sampling method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210444255.1A CN114886470A (en) | 2022-04-24 | 2022-04-24 | Automatic throat swab nucleic acid sampling device and nucleic acid sampling method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114886470A true CN114886470A (en) | 2022-08-12 |
Family
ID=82718664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210444255.1A Pending CN114886470A (en) | 2022-04-24 | 2022-04-24 | Automatic throat swab nucleic acid sampling device and nucleic acid sampling method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114886470A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115212773A (en) * | 2022-09-21 | 2022-10-21 | 融越医疗科技(江苏)有限公司 | Mixer for nucleic acid mixing detection and use method thereof |
| CN115402743A (en) * | 2022-08-16 | 2022-11-29 | 上海弗睿思医疗科技有限公司 | Automatic cotton swab delivery device and nucleic acid collection and sorting platform adopting same |
| CN115504213A (en) * | 2022-09-04 | 2022-12-23 | 百福泰(青岛)防护科技有限公司 | Automatic broken collecting system of breaking off with fingers and thumb of throat swab head |
| CN115736995A (en) * | 2022-11-08 | 2023-03-07 | 黑龙江中医药大学 | Integrated intelligent swab sampler |
| CN115770069A (en) * | 2022-12-23 | 2023-03-10 | 东海县裕隆医学检验实验室有限公司 | Self-service nucleic acid sampling machine |
| CN116814407A (en) * | 2023-08-31 | 2023-09-29 | 泰州蕾灵百奥生物科技有限公司 | Integrated nucleic acid sample detection device and detection method |
-
2022
- 2022-04-24 CN CN202210444255.1A patent/CN114886470A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115402743A (en) * | 2022-08-16 | 2022-11-29 | 上海弗睿思医疗科技有限公司 | Automatic cotton swab delivery device and nucleic acid collection and sorting platform adopting same |
| CN115504213A (en) * | 2022-09-04 | 2022-12-23 | 百福泰(青岛)防护科技有限公司 | Automatic broken collecting system of breaking off with fingers and thumb of throat swab head |
| CN115212773A (en) * | 2022-09-21 | 2022-10-21 | 融越医疗科技(江苏)有限公司 | Mixer for nucleic acid mixing detection and use method thereof |
| CN115736995A (en) * | 2022-11-08 | 2023-03-07 | 黑龙江中医药大学 | Integrated intelligent swab sampler |
| CN115770069A (en) * | 2022-12-23 | 2023-03-10 | 东海县裕隆医学检验实验室有限公司 | Self-service nucleic acid sampling machine |
| CN115770069B (en) * | 2022-12-23 | 2023-10-13 | 东海县裕隆医学检验实验室有限公司 | Self-help nucleic acid sampling machine |
| CN116814407A (en) * | 2023-08-31 | 2023-09-29 | 泰州蕾灵百奥生物科技有限公司 | Integrated nucleic acid sample detection device and detection method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN114886470A (en) | Automatic throat swab nucleic acid sampling device and nucleic acid sampling method | |
| JP6739531B2 (en) | Vacuum blood collection tube labeling machine, vacuum blood collection tube transporting and labeling method | |
| WO2018209906A1 (en) | Automatic medication dispensing device | |
| CN111975799A (en) | Nasal oropharynx swab sampling robot | |
| CN212471524U (en) | Nasal oropharynx swab sampling robot | |
| CN214632201U (en) | Integral type pharynx swab self-service sampling device | |
| CN112263283B (en) | Self-help sampling method for throat swab | |
| CN112107334A (en) | Integral type pharynx swab self-service sampling device | |
| CN112137656A (en) | Split type pharynx swab self-service sampling device | |
| CN109294897B (en) | Intelligent robot for pretreatment of microbial samples | |
| CN109520882A (en) | Coal ' moisture analysis system | |
| CN115478004A (en) | Self-service nucleic acid detection device and self-service nucleic acid detection method | |
| CN115399812A (en) | Automatic workstation is gathered to pharynx swab | |
| CN110631877B (en) | Tripping and separating mechanism for liquid-based cell film production | |
| CN115478713A (en) | Oropharynx sampling robot system | |
| CN116835155A (en) | Intelligent formula machine for small-package traditional Chinese medicine decoction pieces | |
| CN113576545A (en) | Pharynx examination unmanned on duty's automatic sampling device | |
| CN114214183A (en) | Automatic nucleic acid extraction equipment and nucleic acid extraction method thereof | |
| CN113043307A (en) | Clinical laboratory uses safe sampling device | |
| CN111439713A (en) | Automatic auxiliary cover opening and closing machine | |
| CN215739122U (en) | Pharynx examination unmanned on duty's automatic sampling device | |
| CN217872037U (en) | Automatic workstation is gathered to pharynx swab | |
| CN214694093U (en) | Nucleic acid sampling storehouse limit structure | |
| CN109669016A (en) | It is a kind of based on the food safety detection equipment transferred at random and its working method | |
| CN207409266U (en) | A kind of clinical labororatory's sample core receives system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |