CN114869830B - Whitening acne-removing essence and preparation method thereof - Google Patents
Whitening acne-removing essence and preparation method thereof Download PDFInfo
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- CN114869830B CN114869830B CN202210571211.5A CN202210571211A CN114869830B CN 114869830 B CN114869830 B CN 114869830B CN 202210571211 A CN202210571211 A CN 202210571211A CN 114869830 B CN114869830 B CN 114869830B
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- extract
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- acne
- oat
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Abstract
The application relates to the field of cosmetics, and in particular discloses a whitening acne-removing essence which comprises the following components in percentage by mass: 0.08% -0.12% of tricholoma matsutake extract; 0.06% -0.15% of Hamamelis virginiana extract; 0.10% -0.18% of oat extract; 0.15% -0.42% of thickener; the balance being solvent. The application also discloses a preparation method of the whitening acne-removing essence, which comprises the following steps: s1: mixing Tricholoma matsutake extract, hamamelis virginiana extract and herba Avenae Fatuae extract, heating to 45-48deg.C, and stirring to obtain a first mixed solution; s2: heating the solvent and the thickener to 65-70 ℃, and uniformly stirring to obtain a second mixed solution; s3: and cooling the second mixed solution to 45-48 ℃, and uniformly stirring the first mixed solution and the second mixed solution to obtain the whitening acne-removing essence. The essence has the effects of whitening and acne removing.
Description
Technical Field
The application relates to the field of cosmetics, in particular to a whitening and acne-removing essence and a preparation method thereof.
Background
In recent years, with the improvement of life quality and the continuous enhancement of health care consciousness, and the increase of people's chong and returning to natural demands, more and more cosmetics are developed, and especially, plant extract cosmetics with small side effects and less toxicity are more and more favored by people. The plant extract is a plant product mainly composed of biological small molecules and high molecules, which is formed by separating and purifying one or more active ingredients in plant raw materials by physical, chemical, biological and other means. At present, the plant extract is widely applied to the fields of natural pharmaceutical preparations, health-care foods, cosmetics and the like.
At present, researches report that more natural plant extracts mainly comprise saponins, alkaloids, polysaccharides, tea polyphenols, flavonoids, volatile oil and the like, and the functional components and related action mechanisms of the natural plant extracts are gradually discovered and proved by people, and the natural plant extracts have remarkable effects on whitening, anti-aging, acne removal and the like, so that the effective components of the plant extracts are fully applied to essence, and are welcomed by people.
When people want the essence to have the whitening effect and the acne removing effect, the plant extracts with the whitening effect and the plant extracts with the acne removing effect are usually selected to be matched with each other, but when different plant extracts are matched, the problem that the drug effects are mutually influenced can exist, so that the whitening effect and the acne removing effect of the essence are influenced. Thus, there is still room for improvement.
Disclosure of Invention
In order to enable the essence to have good whitening and acne removing effects at the same time, the application provides a whitening and acne removing essence and a preparation method thereof.
In a first aspect, the application provides a whitening and acne-removing essence, which adopts the following technical scheme:
the application provides a whitening acne-removing essence, which adopts the following technical scheme:
the whitening acne-removing essence comprises the following components in percentage by mass:
0.08% -0.12% of tricholoma matsutake extract;
0.06% -0.15% of Hamamelis virginiana extract;
0.10% -0.18% of oat extract;
0.15% -0.42% of thickener;
the balance being solvent;
the total mass percentage is 100%.
By adopting the technical scheme, the tricholoma matsutake crude polysaccharide in the tricholoma matsutake extract has good inhibition effect on tyrosinase, the purpose of whitening skin can be achieved by intervening in the occurrence process of melanin deposition, and the essence has the effect of whitening and tightening the skin by adding the tricholoma matsutake extract.
By adding the Hamamelis virginiana extract, the Hamamelis virginiana contains a plurality of compounds with antibacterial and anti-inflammatory effects, including gallic acid and tannin, which are helpful for treating skin inflammation problems, such as acne, eczema or psoriasis, so that the essence has the acne-removing effect.
By adding oat extract, oat extract is rich in a plurality of nutrients, has the effect of nourishing skin, and beta-glucan contained in oat extract can promote collagen synthesis, eliminate free radicals, and has the effects of resisting oxidation, reducing skin wrinkles and preventing aging; the essence has good moisturizing effect and long-lasting moisturizing effect.
The tricholoma matsutake extract and the witch hazel extract are added simultaneously to be matched, so that the whitening effect of the tricholoma matsutake extract is promoted. By adding the oat extract, the oat extract and the tricholoma matsutake extract are mutually cooperated, the inhibition of the tricholoma matsutake extract on the antibacterial and anti-inflammatory effects of the tricholoma matsutake extract are relieved, and the oat extract, the tricholoma matsutake extract and the witch hazel extract are mutually cooperated, so that the whitening effect of the tricholoma matsutake extract is promoted, the antibacterial and anti-inflammatory effects of the tricholoma matsutake extract are promoted, and the essence has good whitening and acne removing effects.
Preferably, the whitening acne-removing essence also comprises the following components in percentage by mass:
0.04% -0.10% of coconut extract;
0.02% -0.09% of hibiscus flower extract.
By adopting the technical scheme, the coconut extract has good inhibition effect on metalloprotease, and the activity of the metalloprotease can be regarded as an index of organism aging, so that the coconut extract has good anti-aging effect; the hibiscus flower extract can effectively inhibit melanin generation, prevent freckle generation, has good freckle-lightening effect, can supplement needed nutrition for skin, and ensures smooth and white skin. Therefore, the coconut extract and the hibiscus flower extract are mutually matched in a synergistic way, so that the anti-aging effect of the essence is obviously improved, and meanwhile, the whitening and freckle-removing effects of the essence are also improved, so that the essence can meet the demands of people.
Preferably, the whitening acne-removing essence also comprises the following components in percentage by mass:
2.2% -4.0% of humectant;
the humectant comprises ceramide and vitamin B, wherein the mass ratio of the ceramide to the vitamin B is 0.5:0.8.
By adopting the technical scheme, the ceramide and the vitamin B with specific proportions are adopted as the humectant, so that the antibacterial and anti-inflammatory effects of the Hamamelis mollis extract are promoted, the essence has good acne removing effects, the skin is relieved, and the skin is not easy to be allergic.
Preferably, the whitening acne-removing essence also comprises the following components in percentage by mass:
0.02% -0.05% of extract of radix polygoni multiflori;
0.06% -1.1% of centella asiatica extract;
hyaluronic acid 0.15% -0.20%;
0.1% -0.2% of nicotinamide.
By adopting the technical scheme, the substances are added into the essence, so that free radicals are eliminated, skin metabolism is increased, skin elasticity is increased, the essence has good anti-wrinkle effect, sebum is improved, skin is soft, and the essence has an anti-allergy effect.
Preferably, the solvent is one or more of butanediol, ethanol, glycerol and isopropanol.
By adopting the technical scheme, the solvent is harmless to human bodies, so that the essence is not easy to stimulate the skin, and the solvent is also beneficial to improving the compatibility among the components, so that the components are better matched, and the whitening and acne removing effects of the essence are better promoted.
Preferably, the thickener consists of xanthan gum and guar gum in a mass ratio of 0.8:1.
By adopting the technical scheme, the xanthan gum and guar gum with specific proportions are adopted as the thickening agent, so that the whitening and acne removing effects of the essence are further improved, the essence has better performance, and the requirements of people are met.
Preferably, the oat extract extraction method comprises the following steps:
s1: firstly, crushing oat in a crusher, then adding 75% ethanol, and uniformly mixing to obtain oat mixed solution;
s2: adding cellulase into the oat mixed solution, adjusting the pH value to 5.5, and stirring to fully perform enzymolysis reaction to obtain a product;
s3: and (3) carrying out centrifugal separation on the product after the enzymolysis reaction is finished, carrying out subcritical extraction on the separated solid, extracting the solvent with dimethyl ether as an extracting agent, and then carrying out reduced pressure distillation to recover the solvent to obtain the oat extract.
By adopting the technical scheme, the oat extract obtained by the method is matched with the tricholoma matsutake extract and the witch hazel extract in a synergistic manner, so that the whitening effect of the tricholoma matsutake extract is promoted, and meanwhile, the acne removing effect of the witch hazel extract is further improved, so that the essence has good whitening and acne removing effects.
Preferably, beta-amylase is also added into the S2, and the mass ratio of the beta-amylase to the cellulase is 1.2:1.
By adopting the technical scheme, the beta-amylase and the cellulase in a specific proportion are matched with each other, so that the synergistic effect of the oat extract, the tricholoma matsutake extract and the witch hazel extract is promoted, and the whitening and acne removing effects of the essence are further improved.
In a second aspect, the application provides a preparation method of whitening and acne-removing essence, which adopts the following technical scheme:
a preparation method of whitening and acne-removing essence comprises the following steps:
s1: mixing Tricholoma matsutake extract, hamamelis virginiana extract and herba Avenae Fatuae extract according to the formula, heating to 45-48deg.C, and stirring to obtain a first mixed solution;
s2: mixing the solvent and the thickener, heating to 65-70 ℃, stirring uniformly, and preserving heat for 15-20min after the thickener is completely dissolved to obtain a second mixed solution;
s3: and cooling the second mixed solution to 45-48 ℃, adding the first mixed solution into the second mixed solution, and uniformly stirring to obtain the whitening acne-removing essence.
By adopting the technical scheme, the tricholoma matsutake extract, the witch hazel extract and the oat extract are heated to 45-48 ℃ to keep the optimal activity, then the thickener and the solvent are heated to 65-70 ℃ to ensure that the thickener is dispersed in the solvent more uniformly, further the thickening effect of the thickener is improved, and finally the first mixed solution and the second mixed solution are uniformly mixed at the temperature of 45-48 ℃ to ensure that the activity of the essence is optimal.
Preferably, glycerol monostearate and sodium laurate sulfate are also added to S2.
Through adopting above-mentioned technical scheme, research and development personnel occasionally find that layering phenomenon always appears when first mixed solution and second mixed solution are stirred for a small amount of precipitation appears in the essence, and through a large amount of experimental researches, it is found that adding glycerol monostearate and sodium laurate, when making second mixed solution and first mixed solution mix, layering phenomenon is difficult to appear, and then the precipitation is difficult to appear in the essence that makes the preparation obtain, thereby makes the quality and the efficiency of essence obtain better assurance.
In summary, the present application includes at least one of the following beneficial technical effects:
1. by adopting oat extract, the oat extract and the tricholoma matsutake extract are mutually cooperated, the inhibition of the tricholoma matsutake extract on the antibacterial and anti-inflammatory effects of the tricholoma matsutake extract are relieved, and the whitening effect of the tricholoma matsutake extract and the antibacterial and anti-inflammatory effects of the tricholoma matsutake extract are facilitated.
2. The coconut extract and the hibiscus flower extract are mutually matched in a synergistic way, so that the anti-aging effect of the essence is improved, and meanwhile, the whitening and freckle-removing effects of the essence are remarkably improved, so that the essence can meet the demands of people.
3. By adopting the method for extracting the oat extract, the oat extract is matched with the tricholoma matsutake extract and the witch hazel extract in a synergistic manner, so that the whitening effect of the tricholoma matsutake extract is promoted, and meanwhile, the acne removing effect of the witch hazel extract is further improved, so that the essence has good whitening and acne removing effects.
4. The essence prepared by the method has simple process and better activity.
Detailed Description
The present application is described in further detail below with reference to examples.
Example 1
The embodiment discloses a whitening acne-removing essence, which comprises the following components:
an extract of matsutake; hamamelis virginiana extract; oat extract; the thickener is carbomer; the solvent is deionized water.
Wherein the Tricholoma matsutake extract is obtained from JGT150 sold by Shaanxi Jiaguo peptide bioengineering Co., ltd; hamamelis virginiana extract is sold by Siam Rui Biotechnology Co., ltd. Under the product number RY; oat extract was sold under the trade designation BCSW191204-6 from sialon biotechnology limited.
The embodiment also discloses an extraction method of the oat extract, which comprises the following steps:
s1: firstly, crushing oat in a crusher, then adding 75% ethanol, and uniformly mixing to obtain oat mixed solution;
s2: adding cellulase and beta-amylase into the oat mixed solution, wherein the mass ratio of the beta-amylase to the cellulase is 1.2:1, regulating the pH value to be 5.5, and uniformly stirring at the rotating speed of 60r/min to ensure that the enzymolysis reaction is complete, thus obtaining a product;
s3: and (3) carrying out centrifugal separation on the product after the enzymolysis reaction is finished, carrying out subcritical extraction on the separated solid, extracting the solvent with dimethyl ether as an extracting agent, and then carrying out reduced pressure distillation to recover the solvent to obtain the oat extract.
The embodiment also discloses a preparation method of the whitening acne-removing essence, which comprises the following steps:
s1: mixing Tricholoma matsutake extract, hamamelis virginiana extract and herba Avenae Fatuae extract according to formula (specific dosage is shown in Table 1), heating to 45deg.C, and stirring at 80r/min to obtain first mixed solution;
s2: mixing the solvent and the thickener, heating to 65 ℃, uniformly stirring at a rotating speed of 100r/min, and preserving heat for 15min after the thickener is completely dissolved to obtain a second mixed solution;
s3: and cooling the second mixed solution to 45 ℃, adding the first mixed solution into the second mixed solution, and uniformly stirring at a rotating speed of 120r/min to obtain the whitening acne-removing essence.
Example 2
The difference from example 1 is that: a preparation method of whitening and acne-removing essence comprises the following steps:
s1: mixing Tricholoma matsutake extract, hamamelis virginiana extract and herba Avenae Fatuae extract according to formula (specific dosage is shown in Table 1), heating to 48deg.C, and stirring at 80r/min to obtain first mixed solution;
s2: mixing the solvent and the thickener, heating to 70 ℃, uniformly stirring at a rotating speed of 100r/min, and preserving heat for 20min after the thickener is completely dissolved to obtain a second mixed solution;
s3: and cooling the second mixed solution to 48 ℃, adding the first mixed solution into the second mixed solution, and uniformly stirring at a rotating speed of 120r/min to obtain the whitening acne-removing essence.
Example 3
The difference from example 1 is that: a preparation method of whitening and acne-removing essence comprises the following steps:
s1: mixing Tricholoma matsutake extract, hamamelis virginiana extract and herba Avenae Fatuae extract according to formula (specific dosage is shown in Table 1), heating to 46 deg.C, and stirring at 80r/min to obtain first mixed solution;
s2: mixing the solvent and the thickener, heating to 68 ℃, uniformly stirring at a rotating speed of 100r/min, and preserving heat for 18min after the thickener is completely dissolved to obtain a second mixed solution;
s3: and cooling the second mixed solution to 46 ℃, adding the first mixed solution into the second mixed solution, and uniformly stirring at a rotating speed of 120r/min to obtain the whitening acne-removing essence.
The amounts of the components used in examples 1 to 3 are shown in Table 1, and the unit of the amounts of the components used is kg.
TABLE 1
Examples 4 to 5
The difference from example 3 is that: the components of the whitening acne-removing essence also comprise coconut extract and hibiscus flower extract, and the input amounts (unit kg) of the coconut extract and the hibiscus flower extract are shown in table 2.
TABLE 2
| Example 4 | Example 5 | |
| Coconut extract | 0.04 | 0.10 |
| Hibiscus flower extract | 0.02 | 0.09 |
Example 6
The difference from example 5 is that: the extract of hibiscus flower is replaced by the same amount of coconut extract.
Example 7
The difference from example 5 is that: the coconut extract was replaced with an equivalent amount of hibiscus flower extract.
Examples 8 to 9
The difference from example 3 is that: the whitening acne-removing essence also comprises a humectant, wherein the humectant comprises ceramide and vitamin B, and the specific dosage is shown in Table 3 and the unit kg.
TABLE 3 Table 3
| Example 8 | Example 9 | |
| Ceramide | 0.85 | 1.54 |
| Vitamin B | 1.35 | 2.46 |
| Totals to | 2.2 | 4.0 |
Examples 10 to 11
The difference from example 3 is that: the whitening acne-removing essence also comprises the components of the extract of the root of Boschniakia rossica, the extract of centella asiatica, hyaluronic acid and nicotinamide, wherein the specific dosage is shown in Table 4, and the unit kg.
TABLE 4 Table 4
| Example 10 | Example 11 | |
| Extract of radix seu cortex Heteropanacis | 0.02 | 0.05 |
| Centella asiatica extract | 0.06 | 1.10 |
| Hyaluronic acid | 0.15 | 0.20 |
| Nicotinamide | 0.10 | 0.20 |
Example 12
The difference from example 3 is that: and the S2 is also added with glycerin monostearate and sodium laurate sulfate, wherein the mass of the glycerin monostearate and the mass of the sodium laurate sulfate are respectively 0.10kg and 0.13kg.
Example 13
The difference from example 3 is that:
a whitening and acne-removing essence comprises the following components in mass:
0.12kg of tricholoma matsutake extract; 0.10kg of Hamamelis virginiana extract; 0.15kg of oat extract; 0.08kg of coconut extract; 0.06kg of hibiscus flower extract; the humectant comprises ceramide and vitamin B, wherein the mass of the ceramide and the vitamin B is respectively 0.85kg and 1.35kg; 0.04kg of a yellow carefully root extract; 1.0kg of centella asiatica extract; hyaluronic acid 0.18kg; 0.14kg of nicotinamide; the thickener consists of xanthan gum and guar gum, wherein the mass of the xanthan gum is 0.8kg, and the mass of the guar gum is 1.0kg; the solvent is ethanol, and the mass of the ethanol is 94.13kg.
Comparative example 1
The difference from example 3 is that: the matsutake extract, witch hazel extract and oat extract are replaced with equal amounts of deionized water.
Comparative example 2
The difference from example 3 is that: the extracts of Hamamelis virginiana and Avena sativa are replaced with equal amount of deionized water.
Comparative example 3
The difference from example 3 is that: the matsutake extract and oat extract are replaced with equal amounts of deionized water.
Comparative example 4
The difference from example 3 is that: the pine mushroom extract and Hamamelis mollis extract are replaced with equal amount of deionized water.
Comparative example 5
The difference from example 3 is that: the oat extract was replaced with an equal amount of deionized water.
Comparative example 6
The difference from example 3 is that: the matsutake extract was replaced with an equal amount of deionized water.
Comparative example 7
The difference from example 3 is that: the witch hazel extract was replaced with an equal amount of deionized water.
Comparative example 8
The difference from example 3 is that: the oat extract is replaced by the same amount of aloe stem and leaf extract.
Comparative example 9
The difference from example 3 is that: a whitening and acne-removing essence comprises the following components in mass:
0.21kg of tricholoma matsutake extract; 0.02kg of Hamamelis virginiana extract; 0.25kg of oat extract; the thickener is carbomer, and the mass is 0.08kg; 99.44kg of deionized water.
Experiment 1 tyrosinase activity inhibition assay
According to the cosmetic-tyrosinase activity inhibition test method (T/SHRH 015-2018), the inhibition rate (%) of tyrosinase of the whitening and acne-removing essence prepared in the above examples and comparative examples is respectively detected, and the higher the inhibition rate, the better the whitening effect of the whitening and acne-removing essence is.
Experiment 2DPPH free radical scavenging experiment
According to the experiment method (T/SHRH 006-2018) of scavenging free radicals of cosmetics (DPPH), the scavenging rate (%) of DPPH free radicals of the whitening and acne-removing essence prepared in the above examples and comparative examples is respectively detected, and the higher the scavenging rate is, the better the anti-wrinkle effect of the whitening and acne-removing essence is.
Experiment 3 test for inhibition of Propionibacterium acnes
(1) Test sample: the extracts prepared in examples 1 to 13 and the extracts prepared in comparative examples 1 to 9 were propionibacterium acnes strain 3 (isolated from skin lesions of acne patients).
(2) The test method comprises the following steps:
(1) culturing, separating and identifying anaerobic bacteria: inoculating the sample obtained by separating skin lesions of acne patients into THl culture medium, culturing in anaerobic jar at 37deg.C for 72 hr by air bag method, and taking blue as indicator and palladium particles as catalytic thorns.
(2) Separation of anaerobic bacteria
Picking single bacterial colony, transferring to 2 flat plates, placing one plate into an anaerobic tank, and performing pure culture at 37 ℃ under anaerobic conditions; the other block was cultivated aerobically at 37 ℃; after 48h the results were observed.
(3) Identification of anaerobic bacteria no bacterial growth under aerobic culture; colonies with uniform, off-white, fine and round protrusions with diameters of about 1.0mm and slightly aligned edges appear on the anaerobic culture plates, and the colonies are subjected to microscopic examination to visualize the purple bacillus under the microscope. Microbending is in a rod shape or a rod shape, one end of the microbending is blunt, the other end of the microbending is thin, the cells are single, and the microbending can be arranged in pairs or in a shape like a human body or a v. And the propionibacterium acnes are identified by an oxygen-resistant test, a thixotropic enzyme test, an indole test and a biochemical series test.
(4) Anaerobic drug sensitivity test
Strain inoculation: 1 colony of the cultured colonies is picked and inoculated on an LB plate medium, aerobic culture is carried out for 24 hours at 370 ℃, propionibacterium acnes which are aerobically cultured for 24 hours is washed by sterile normal saline, and the washing liquid is put into a sterile test tube; turbidimetry is adopted, the turbidimetry is carried out for 12 times before the turbidimetry tube is used, the turbidimetry is carried out to 3X 108/mL, and then the turbidimetry is diluted to 106/mL for standby.
Inoculating LB plate medium: dipping sterilized cotton sticks in bacterial liquid, squeezing excessive bacterial liquid on the pipe wall, uniformly coating on an LB plate culture medium, sweeping a circle along the edge of a plate, covering the plate, and drying for 2min. The sterile steel cup (diameter of 6 mm) was placed on a plate culture medium, the essence obtained in examples and comparative examples was filled up, and the plate was placed in 37℃for aerobic culture for 24 hours, and no bacterial growth was found in the plate, and after continuing the aerobic culture at 37℃for 24 hours, a zone of inhibition was found to be formed. The diameter of the inhibition zone is measured, and the diameter values of the 3 groups of inhibition zones are averaged.
Test results:
the antibacterial sensitization of traditional Chinese medicines is classified according to corresponding antibiotic standards. The diameter of the inhibition ring is higher than 20mm, the inhibition ring is middle sensitivity and is 10-20 mm, the inhibition ring is larger in diameter, the better acne removing effect of the essence is shown in table 6.
Experiment 4 subject use feeling test
4.1 test crowd
The temperature of the test environment is 20-22 ℃, the humidity is 40-60%, and real-time dynamic monitoring is carried out. The subjects were 18-45 years old, 30 subjects were all, and each subject was numbered separately, and the essence prepared in experimental examples 1-13 and comparative examples 1-9 was applied to the face and neck using the same method.
4.2 test samples: experimental examples 1 to 13, comparative examples 1 to 9.
4.3 test procedure
4.3.1 preparation before testing
No product (cosmetic or topical medicine) can be used 2-3 days before testing the test site. 1h-3h cannot contact water. Prior to testing, subjects were required to uniformly clean the face and neck, and were wiped clean with dry facial tissues. After cleaning, the face and neck of the subject are marked with measurement areas. Before formal test, the test bed should sit still for 30min in a room meeting the standard, can not drink water, and is placed in a test state to be kept relaxed.
4.3.2 test procedure
In the experiment, the face and neck were marked with 2cm x 2cm test areas, and the face and neck were marked with multiple areas at 1cm intervals. The plurality of regions are evenly distributed over the face and neck. The subjects were respectively smeared with the essences of experimental examples 1-13 and comparative examples 1-9, and the test samples were measured at a ratio of (3.0.+ -. 0.1) mg/cm 2 The test product was uniformly coated in the test area using latex fingerstall, and each sample was applied for each week in the morning and evening, respectively.
After application, 30 volunteers were scored for skin lightening changes, wrinkle changes, and acne treatment effects on the skin, respectively (0-100 points).
The scoring criteria for each of the above are shown in Table 5.
TABLE 5
After the subjects smear the essence, whether the whitening effect of the essence is good can be obtained through the grading of the change of the skin brightness of the subjects on the skin; the anti-wrinkle effect of the essence can be obtained by scoring the change of the wrinkles of the skin by a subject; through scoring the acne removing effect of the subject on the skin, whether the acne removing effect of the essence is good or not can be obtained.
The above experimental data are shown in Table 6.
TABLE 6
From the data analysis of comparative examples 1 to 7 in Table 6, comparative example 2 was newly added with Tricholoma matsutake extract based on comparative example 1, and the inhibition rate was increased from 0.42% to 32.51%, which indicates that the Tricholoma matsutake extract has whitening effect; comparative example 3 the addition of the witch hazel extract of comparative example 1, the diameter of the zone of inhibition increased from 1.2mm to 15.3mm, shows that the witch hazel extract of north america has the effect of acne removal; comparative example 4 the oat extract was newly added on the basis of comparative example 1, and the free radical scavenging rate was increased from 0.15% to 39.72%, indicating that the oat extract has anti-wrinkle effect.
Comparative example 5, which is based on comparative example 2, further added with hamamelis extract, the inhibition rate is increased from 32.51% to 63.43%, which means that the addition of tricholoma matsutake extract and hamamelis extract is beneficial to improving the whitening effect of the essence; the diameter of the inhibition zone is reduced from 15.3mm to 8.8mm, which shows that the tricholoma matsutake extract inhibits the acne-removing effect of the witch hazel extract.
According to the comparison of the data of the comparative example 5 and the data of the example 3, the example 3 is newly added with oat extract on the basis of the comparative example 5, the inhibition rate is increased from 63.43% to 69.53%, and the diameter of a bacteriostasis zone is increased from 8.8mm to 20.5mm, which shows that the addition of oat extract is beneficial to alleviating the inhibition effect of the tricholoma matsutake extract on the acne removing effect of the witch hazel extract, not only is beneficial to promoting the whitening effect of the essence, but also is beneficial to promoting the acne removing effect of the essence, so that the essence has better whitening and acne removing effects at the same time.
From the comparison of the data in Table 6 for examples 4-7 with example 3, respectively, the inhibition rate was substantially similar to that of example 3, and the radical scavenging rate was also substantially similar to that of example 3, with the addition of coconut extract alone in example 6 based on example 3; example 7 the extract of hibiscus flower was added alone on the basis of example 3, the inhibition rate was substantially similar to that of example 3, and the free radical scavenging rate was also substantially similar; however, examples 4-5 added coconut extract and hibiscus flower extract simultaneously on the basis of example 3, the inhibition rate increased from 69.53% to about 75%, and the free radical scavenging rate increased from 48.52% to about 63%, which means that the addition of coconut extract and hibiscus flower extract simultaneously cooperate with each other, which is not only beneficial to improving the whitening effect of the essence, but also beneficial to improving the anti-wrinkle effect of the essence.
According to the data of examples 8-9 in Table 6, which are respectively compared with example 3, the data of examples 8-9 are obtained, and on the basis of example 3, ceramide and vitamin B are added simultaneously, so that the diameter of a inhibition zone is increased from 20.5mm to about 22mm, and the fact that the ceramide and the vitamin B with specific proportions are adopted as a humectant is beneficial to promoting the antibacterial and anti-inflammatory effects of the Hamamelis virginiana extract, so that the essence has a good acne removing effect.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.
Claims (5)
1. A whitening acne-removing essence is characterized in that: comprises the following components in percentage by mass:
0.08% -0.12% of tricholoma matsutake extract;
0.06% -0.15% of Hamamelis virginiana extract;
0.10% -0.18% of oat extract;
0.15% -0.42% of thickener;
0.04% -0.10% of coconut extract;
0.02% -0.09% of hibiscus flower extract;
0.02% -0.05% of extract of radix polygoni multiflori;
0.06% -1.1% of centella asiatica extract;
hyaluronic acid 0.15% -0.20%;
0.1% -0.2% of nicotinamide;
2.2% -4.0% of humectant;
the humectant comprises ceramide and vitamin B, wherein the mass ratio of the ceramide to the vitamin B is 0.5:0.8;
the balance being solvent;
the total mass percentage is 100%.
2. The whitening and acne-removing essence according to claim 1, wherein the essence is characterized in that: the solvent is one or more of butanediol, ethanol, glycerol and isopropanol.
3. The whitening and acne-removing essence according to claim 1, wherein the essence is characterized in that: the thickener consists of xanthan gum and guar gum in a mass ratio of 0.8:1.
4. The whitening and acne-removing essence according to claim 1, wherein the essence is characterized in that: the extraction method of the oat extract comprises the following steps:
s1: firstly, crushing oat in a crusher, then adding 75% ethanol, and uniformly mixing to obtain oat mixed solution;
s2: adding cellulase into the oat mixed solution, adjusting the pH value to 5.5, and stirring to fully perform enzymolysis reaction to obtain a product;
s3: and (3) carrying out centrifugal separation on the product after the enzymolysis reaction is finished, carrying out subcritical extraction on the separated solid, extracting the solvent with dimethyl ether as an extracting agent, and then carrying out reduced pressure distillation to recover the solvent to obtain the oat extract.
5. The whitening and acne-removing essence according to claim 4, wherein the essence is characterized in that: and beta-amylase is also added into the S2, and the mass ratio of the beta-amylase to the cellulase is 1.2:1.
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| CN109199985A (en) * | 2018-11-16 | 2019-01-15 | 董志林 | A kind of anti-ageing Essence factory formula |
| CN111821230A (en) * | 2020-06-01 | 2020-10-27 | 钟意生物技术(广州)有限公司 | Anti-allergy repairing cosmetic composition and application thereof |
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| CN109199985A (en) * | 2018-11-16 | 2019-01-15 | 董志林 | A kind of anti-ageing Essence factory formula |
| CN111821230A (en) * | 2020-06-01 | 2020-10-27 | 钟意生物技术(广州)有限公司 | Anti-allergy repairing cosmetic composition and application thereof |
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