CN114845640B - 导航支气管路径 - Google Patents
导航支气管路径Info
- Publication number
- CN114845640B CN114845640B CN202080087689.XA CN202080087689A CN114845640B CN 114845640 B CN114845640 B CN 114845640B CN 202080087689 A CN202080087689 A CN 202080087689A CN 114845640 B CN114845640 B CN 114845640B
- Authority
- CN
- China
- Prior art keywords
- intrathoracic
- bronchial
- navigation
- ray
- image data
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/12—Arrangements for detecting or locating foreign bodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
- A61B6/4064—Arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
- A61B6/4085—Cone-beams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/44—Constructional features of apparatus for radiation diagnosis
- A61B6/4417—Constructional features of apparatus for radiation diagnosis related to combined acquisition of different diagnostic modalities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/46—Arrangements for interfacing with the operator or the patient
- A61B6/461—Displaying means of special interest
- A61B6/463—Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/46—Arrangements for interfacing with the operator or the patient
- A61B6/461—Displaying means of special interest
- A61B6/466—Displaying means of special interest adapted to display 3D data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/486—Diagnostic techniques involving generating temporal series of image data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
- A61B6/5247—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5258—Devices using data or image processing specially adapted for radiation diagnosis involving detection or reduction of artifacts or noise
- A61B6/5264—Devices using data or image processing specially adapted for radiation diagnosis involving detection or reduction of artifacts or noise due to motion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/10—Segmentation; Edge detection
- G06T7/11—Region-based segmentation
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/20—Analysis of motion
- G06T7/246—Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
- A61B2034/107—Visualisation of planned trajectories or target regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2051—Electromagnetic tracking systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2065—Tracking using image or pattern recognition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/486—Diagnostic techniques involving generating temporal series of image data
- A61B6/487—Diagnostic techniques involving generating temporal series of image data involving fluoroscopy
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10016—Video; Image sequence
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10072—Tomographic images
- G06T2207/10081—Computed x-ray tomography [CT]
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10116—X-ray image
- G06T2207/10121—Fluoroscopy
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10132—Ultrasound image
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30021—Catheter; Guide wire
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30061—Lung
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30096—Tumor; Lesion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Optics & Photonics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Theoretical Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Human Computer Interaction (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pulmonology (AREA)
- Robotics (AREA)
- Multimedia (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19217043.9 | 2019-12-17 | ||
| EP19217043.9A EP3838159A1 (en) | 2019-12-17 | 2019-12-17 | Navigating bronchial pathways |
| PCT/EP2020/085661 WO2021122344A1 (en) | 2019-12-17 | 2020-12-11 | Navigating bronchial pathways |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114845640A CN114845640A (zh) | 2022-08-02 |
| CN114845640B true CN114845640B (zh) | 2025-11-28 |
Family
ID=68944254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080087689.XA Active CN114845640B (zh) | 2019-12-17 | 2020-12-11 | 导航支气管路径 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12048494B2 (https=) |
| EP (2) | EP3838159A1 (https=) |
| JP (1) | JP2023506079A (https=) |
| CN (1) | CN114845640B (https=) |
| WO (1) | WO2021122344A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7714431B2 (ja) * | 2021-10-18 | 2025-07-29 | Hoya株式会社 | プログラム、情報処理方法、情報処理装置及び診断支援システム |
| EP4205690A1 (en) | 2021-12-30 | 2023-07-05 | Koninklijke Philips N.V. | Endobronchial probe tracking |
| WO2023126216A1 (en) | 2021-12-30 | 2023-07-06 | Koninklijke Philips N.V. | Endobronchial probe tracking |
| CN119300767A (zh) * | 2022-06-01 | 2025-01-10 | 皇家飞利浦有限公司 | 引导介入成像设备 |
| EP4285832A1 (en) * | 2022-06-01 | 2023-12-06 | Koninklijke Philips N.V. | Guiding an interventional imaging device |
| CN120643307B (zh) * | 2025-06-20 | 2026-03-03 | 广州医科大学附属第一医院(广州呼吸中心) | 一种基于增强现实的支气管镜路径规划系统、设备及存储介质 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103562959A (zh) * | 2011-03-02 | 2014-02-05 | 皇家飞利浦有限公司 | 用于导航引导的可视化 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6580938B1 (en) * | 1997-02-25 | 2003-06-17 | Biosense, Inc. | Image-guided thoracic therapy and apparatus therefor |
| US7697972B2 (en) | 2002-11-19 | 2010-04-13 | Medtronic Navigation, Inc. | Navigation system for cardiac therapies |
| WO2008086430A1 (en) * | 2007-01-09 | 2008-07-17 | Cyberheart, Inc. | Method for depositing radiation in heart muscle |
| US8219179B2 (en) * | 2008-03-06 | 2012-07-10 | Vida Diagnostics, Inc. | Systems and methods for navigation within a branched structure of a body |
| JP5662326B2 (ja) * | 2008-10-23 | 2015-01-28 | コーニンクレッカ フィリップス エヌ ヴェ | インターベンション・ラジオ波焼灼療法またはペースメーカー設置手順における、仮想的な解剖学的構造を豊かにしたリアルタイム2d撮像のための、心臓および/または呼吸同期画像取得システム |
| US9098899B2 (en) | 2010-05-27 | 2015-08-04 | Koninklijke Philips N.V. | Determining the specific orientation of an object |
| CN102949240B (zh) * | 2011-08-26 | 2014-11-26 | 高欣 | 一种影像导航肺部介入手术系统 |
| US9044254B2 (en) | 2012-08-07 | 2015-06-02 | Covidien Lp | Microwave ablation catheter and method of utilizing the same |
| US10912523B2 (en) * | 2014-03-24 | 2021-02-09 | Intuitive Surgical Operations, Inc. | Systems and methods for anatomic motion compensation |
| WO2016187456A1 (en) * | 2015-05-20 | 2016-11-24 | Gravitas Medical, Inc. | Methods and apparatus for guiding medical care based on sensor data from the gastrointestinal tract |
| CN108024693B (zh) * | 2015-09-10 | 2021-07-09 | 直观外科手术操作公司 | 在图像引导医疗程序中利用跟踪的系统和方法 |
| CN108778113B (zh) * | 2015-09-18 | 2022-04-15 | 奥瑞斯健康公司 | 管状网络的导航 |
| CN119856989A (zh) * | 2016-02-12 | 2025-04-22 | 直观外科手术操作公司 | 用于在图像引导手术中使用配准荧光透视图像的系统和方法 |
| EP4375934A3 (en) * | 2016-02-12 | 2024-07-31 | Intuitive Surgical Operations, Inc. | Systems and methods of pose estimation and calibration of perspective imaging system in image guided surgery |
| EP3503834B1 (en) * | 2016-08-23 | 2024-06-12 | Intuitive Surgical Operations, Inc. | Systems for monitoring patient motion during a medical procedure |
| CN110381841B (zh) * | 2016-10-31 | 2023-10-20 | 博迪维仁医疗有限公司 | 用于医疗成像的夹具及其使用方法 |
| WO2018106950A1 (en) * | 2016-12-08 | 2018-06-14 | Intuitive Surgical Operations, Inc. | Systems and methods for navigation in image-guided medical procedures |
| JP7167030B2 (ja) * | 2017-01-03 | 2022-11-08 | コーニンクレッカ フィリップス エヌ ヴェ | 形状検知デバイスを使用した医療ナビゲーションシステム及びその動作方法 |
| WO2018144636A1 (en) * | 2017-02-01 | 2018-08-09 | Intuitive Surgical Operations, Inc. | Systems and methods of registration for image-guided procedures |
| EP3629882A4 (en) | 2017-05-24 | 2021-05-19 | Body Vision Medical Ltd. | METHODS OF USING RADIAL ENDOBRONCHIC ULTRASONIC PROBES FOR THREE-DIMENSIONAL IMAGE RECONSTRUCTION AND IMPROVED TARGET LOCATION |
| US11801114B2 (en) * | 2017-09-11 | 2023-10-31 | Philipp K. Lang | Augmented reality display for vascular and other interventions, compensation for cardiac and respiratory motion |
| US10650585B2 (en) * | 2018-06-08 | 2020-05-12 | Data Integrity Advisors, Llc | System and method for geometrically-resolved radiographic X-ray imaging |
| US20220142714A1 (en) * | 2019-03-15 | 2022-05-12 | Intuitive Surgical Operations, Inc. | Systems for enhanced registration of patient anatomy |
| US12310770B2 (en) * | 2021-09-14 | 2025-05-27 | GE Precision Healthcare LLC | Method and systems for motion-stabilized clinical tool tracking and visualization |
-
2019
- 2019-12-17 EP EP19217043.9A patent/EP3838159A1/en not_active Withdrawn
-
2020
- 2020-12-11 EP EP20821208.4A patent/EP4076203B1/en active Active
- 2020-12-11 CN CN202080087689.XA patent/CN114845640B/zh active Active
- 2020-12-11 US US17/786,052 patent/US12048494B2/en active Active
- 2020-12-11 JP JP2022536770A patent/JP2023506079A/ja active Pending
- 2020-12-11 WO PCT/EP2020/085661 patent/WO2021122344A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103562959A (zh) * | 2011-03-02 | 2014-02-05 | 皇家飞利浦有限公司 | 用于导航引导的可视化 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3838159A1 (en) | 2021-06-23 |
| JP2023506079A (ja) | 2023-02-14 |
| EP4076203B1 (en) | 2025-02-12 |
| EP4076203A1 (en) | 2022-10-26 |
| WO2021122344A1 (en) | 2021-06-24 |
| CN114845640A (zh) | 2022-08-02 |
| US12048494B2 (en) | 2024-07-30 |
| US20230135733A1 (en) | 2023-05-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11925493B2 (en) | Visualization, navigation, and planning with electromagnetic navigation bronchoscopy and cone beam computed tomography integrated | |
| CN114845640B (zh) | 导航支气管路径 | |
| US20230145993A1 (en) | Apparatuses and Methods for Registering a Real-Time Image Feed From an Imaging Device to a Steerable Catheter | |
| US9265468B2 (en) | Fluoroscopy-based surgical device tracking method | |
| US20200146588A1 (en) | Apparatuses and methods for endobronchial navigation to and confirmation of the location of a target tissue and percutaneous interception of the target tissue | |
| CN110123449B (zh) | 使用标准荧光镜进行局部三维体积重建的系统和方法 | |
| CN110120095B (zh) | 用于使用标准荧光镜的局部三维体积重构的系统和方法 | |
| US12208232B2 (en) | Localization needle | |
| JP2023506079A5 (https=) | ||
| US20150042643A1 (en) | Medical x-ray apparatus | |
| CN106068451A (zh) | 手术装置及其使用方法 | |
| CN117412724A (zh) | 在程序内成像期间评估屏气的系统和方法 | |
| CN121443240A (zh) | 结合影像-体部偏差缩减的内窥镜手术规划与引导方法 | |
| WO2023126216A1 (en) | Endobronchial probe tracking | |
| CN119300785A (zh) | 中空解剖结构中的导航 | |
| CN119300767A (zh) | 引导介入成像设备 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |